Ambystoma mexicanum: A salamander found in Mexican mountain lakes and accounting for about 30 percent of the urodeles used in research. The axolotl remains in larval form throughout its life, a phenomenon known as neoteny.Ambystoma: A genus of the Ambystomatidae family. The best known species are the axolotl AMBYSTOMA MEXICANUM and the closely related tiger salamander Ambystoma tigrinum. They may retain gills and remain aquatic without developing all of the adult characteristics. However, under proper changes in the environment they metamorphose.Urodela: An order of the Amphibia class which includes salamanders and newts. They are characterized by usually having slim bodies and tails, four limbs of about equal size (except in Sirenidae), and a reduction in skull bones.Pleurodeles: A genus of aquatic newts belonging to the family Salamandridae and sometimes referred to as "spiny" tritons. There are two species P. waltlii and P. poireti. P. waltlii is commonly used in the laboratory. Since this genus adapts to aquarium living, it is easy to maintain in laboratories.Regeneration: The physiological renewal, repair, or replacement of tissue.Parabiosis: The experimental joining of two individuals for the purpose of studying the effects of one on the other.Extremities: The farthest or outermost projections of the body, such as the HAND and FOOT.Forelimb: A front limb of a quadruped. (The Random House College Dictionary, 1980)Larva: Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.Amphibians: VERTEBRATES belonging to the class amphibia such as frogs, toads, newts and salamanders that live in a semiaquatic environment.

Modulation of gelatinase activity correlates with the dedifferentiation profile of regenerating salamander limbs. (1/189)

Remodeling of extracellular matrix (ECM) is one of the key events in many developmental processes. In the present study, a temporal profile of gelatinase activities in regenerating salamander limbs was examined zymographically. In addition, the effect of retinoic acid (RA) on these enzyme activities was examined to relate the pattern-duplicating effect of RA in limb regenerates with gelatinase activities. During regeneration, various types of gelatinase activities were detected, and these activities were at their maximum levels at the dedifferentiation stage. Upon treatment with chelating agents EDTA and 1,10-phenanthroline, the enzyme activities were inhibited indicating that those enzymes are likely matrix metalloproteinases (MMPs). Considering the molecular sizes and the decrease of molecular sizes by treatment with p-aminophenylmercuric acetate, an artificial activator of proMMP, some of the gelatinases expressed during limb regeneration are presumed to be MMP-2 and MMP-9. In RA-treated regenerates, overall gelatinase activities increased, especially the MMP-2-like gelatinase activity which increased markedly. These results suggest that MMP-2-like and MMP-9-like gelatinases play a role in ECM remodeling during regeneration, and that gelatinases are involved in the excessive dedifferentiation after RA treatment.  (+info)

The cardiac neural crest in Ambystoma mexicanum. (2/189)

To establish whether a region of the cranial neural crest contributes cells to the developing heart of Ambystoma mexicanum (axolotl), as it does in many other vertebrates, we constructed a fate map for the neural crest in late neurula stage (stage 19-20) embryos. The fluorescent vital dye, Dil, was used as the lineage label. The various regions of the cranial neural folds were identified in relation to such landmarks as the developing forebrain, midbrain and hindbrain, and the appearance and extent of emerging somites. Labelled cells originating in the rhombencephalic region were found in the aortic arches and in the truncus arteriosus, and occasionally in the walls of the conus arteriosus. Cells were also found in the third and fourth branchial arches. Labelled neural crest from the adjacent anterior trunk region appeared neither in the heart nor the visceral skeleton, whereas those from the mesencephalic region contributed to the first hypobranchial cartilage and to the first three branchial arches, but not to the heart. No labelled cells from any of the regions were seen in the ventricle or auricle.  (+info)

Analysis of cranial neural crest migratory pathways in axolotl using cell markers and transplantation. (3/189)

We have examined the ability of normal and heterotopically transplanted neural crest cells to migrate along cranial neural crest pathways in the axolotl using focal DiI injections and in situ hybridization with the neural crest marker, AP-2. DiI labeling demonstrates that cranial neural crest cells migrate as distinct streams along prescribed pathways to populate the maxillary and mandibular processes of the first branchial arch, the hyoid arch and gill arches 1-4, following migratory pathways similar to those observed in other vertebrates. Another neural crest marker, the transcription factor AP-2, is expressed by premigratory neural crest cells within the neural folds and migrating neural crest cells en route to and within the branchial arches. Rotations of the cranial neural folds suggest that premigratory neural crest cells are not committed to a specific branchial arch fate, but can compensate when displaced short distances from their targets by migrating to a new target arch. In contrast, when cells are displaced far from their original location, they appear unable to respond appropriately to their new milieu such that they fail to migrate or appear to migrate randomly. When trunk neural folds are grafted heterotopically into the head, trunk neural crest cells migrate in a highly disorganized fashion and fail to follow normal cranial neural crest pathways. Importantly, we find incorporation of some trunk cells into branchial arch cartilage despite the random nature of their migration. This is the first demonstration that trunk neural crest cells can form cartilage when transplanted to the head. Our results indicate that, although cranial and trunk neural crest cells have inherent differences in ability to recognize migratory pathways, trunk neural crest can differentiate into cranial cartilage when given proper instructive cues.  (+info)

Cloning of cDNAs encoding retinoic acid receptors RAR gamma 1, RAR gamma 2, and a new splicing variant, RAR gamma 3, from Aambystoma mexicanum and characterization of their expression during early development. (4/189)

To analyze retinoic acid (RA) receptor (RAR) expression during early development in the urodele embryo, we have isolated cDNAs for four members of the axolotl (Ambystoma mexicanum) RAR family, namely RAR alpha (NR1B1), aRAR gamma 1 (NR1B3a), aRAR gamma 2 (NR1B3b), and a new splicing variant of aRAR gamma 2, aRAR gamma 3 (NR1B3c), which contains an insertion of five hydrophobic amino acids in the C-terminal region of the DNA binding domain. The temporal expression pattern of the RAR gamma isoforms was established by RT-PCR using total RNA from embryos of different stages. The expression of aRAR gamma 2 coincides with neurulation and is enhanced in the extremities of the embryo's anteroposterior axis. The aRAR gamma 3 is specifically expressed during gastrulation and early neurulation, whereas aRAR gamma 1 is expressed later during organogenesis. Global aRAR gamma 2 mRNA levels, as well as their spatio-temporal expression pattern in the neurula, were not affected by treatment with RA. These results show that several RARs are expressed in the axolotl embryo during early development, and reveal the existence of a new RAR gamma variant.  (+info)

GDNF and GFRalpha-1 are components of the axolotl pronephric duct guidance system. (5/189)

In mammals, secretion of GDNF by the metanephrogenic mesenchyme is essential for branching morphogenesis of the ureteric bud and, thus, metanephric development. However, the expression pattern of GDNF and its receptor complex-the GPI-linked ligand-binding protein, GFRalpha-1, and the Ret tyrosine kinase signaling protein-indicates that it could operate at early steps in kidney development as well. Furthermore, the developing nephric systems of fish and amphibian embryos express components of the GDNF signaling system even though they do not make a metanephros. We provide evidence that GDNF signaling through GFRalpha-1 is sufficient to direct pathfinding of migrating pronephric duct cells in axolotl embryos by: (1) demonstrating that application of soluble GFRalpha-1 to an embryo lacking all GPI-linked proteins rescues PND migration in a dose-dependent fashion, (2) showing that application of excess soluble GFRalpha-1 to a normal embryo inhibits migration and that inhibition is dependent upon GDNF-binding activity, and (3) showing that the PND will migrate toward a GDNF-soaked bead in vivo, but will fail to migrate when GDNF is applied uniformly to the flank. These data suggest that PND pathfinding is accomplished by migration up a gradient of GDNF.  (+info)

Expression and characterization of fibroblast growth factor 8 from Mexican axolotl, Ambystoma mexicanum. (6/189)

Fibroblast growth factor (FGF) has been known to regulate the proliferation and differentiation of a variety of cell types via interaction with a specific FGF receptor on the cell surface. In the present study, Fgf8 cDNA of Mexican axolotl, Ambystoma mexicanum, was expressed in Escherichia coli as an MBP-FGF8 fusion protein. The cell proliferation activity of the recombinant FGF8 (rFGF8) was measured by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazoliumbromide (MTT) assay. The addition of rFGF8 to the culture medium enhanced proliferation of BALB/c 3T3 and BHK21 cells about 1.4-1.5 fold. To analyze the binding activity of rFGF8 to the cell surface, cell surface enzyme linked immunosorbent assay was developed. Comparison of the structure of basic FGF with the computer-simulated structure of FGF8 suggested that Tyr-58, Glu-132, Tyr-139, and Leu-179 might be the potential receptor binding sites. Amino acid substitution muteins of FGF8 were constructed by PCR-derived directed mutagenesis and the muteins were overexpressed in E. coli. The rFGF8 muteins were purified and their binding activities were analyzed. Substitution of Tyr-58 or Glu-132 or Leu-179 of the FGF8 with alanine reduced the binding affinity, while substitution of Tyr-139 with alanine did not alter the binding affinity. These results imply that Tyr-58, Glu-132, and Leu-179 of FGF8 might be involved in its binding to the cell surface.  (+info)

Different regulation of T-box genes Tbx4 and Tbx5 during limb development and limb regeneration. (7/189)

The T-domain transcription factors Tbx4 and Tbx5 have been implicated, by virtue of their limb-type specific expression, in controlling the identity of vertebrate legs and arms, respectively. To study the roles of these genes in developing and regenerating limbs, we cloned Tbx4 and Tbx5 cDNAs from the newt, and generated antisera that recognize Tbx4 or Tbx5 proteins. We show here that, in two urodele amphibians, newts and axolotls, the regulation of Tbx4 and Tbx5 differs from higher vertebrates. At the mRNA and protein level, both Tbx4 and Tbx5 are expressed in developing hindlimbs as well as in developing forelimbs. The coexpression of these genes argues that additional factors are involved in the control of limb type-specific patterns. In addition, newt and axolotl Tbx4 and Tbx5 expression is regulated differently during embryogenesis and regenerative morphogenesis. During regeneration, Tbx5 is exclusively upregulated in the forelimbs, whereas Tbx4 is exclusively upregulated in the hindlimbs. This indicates that, on a molecular level, different regulatory mechanisms control the shaping of identical limb structures and that regeneration is not simply a reiteration of developmental gene programs.  (+info)

Extending the table of stages of normal development of the axolotl: limb development. (8/189)

The existing table of stages of the normal development of the axolotl (Ambystoma mexicanum) ends just after hatching. At this time, the forelimbs are small buds. In this study, we extend the staging series through completion of development of the forelimbs and hindlimbs.  (+info)

*Neoteny

Full neoteny is seen in Ambystoma mexicanum and some populations of Ambystoma tigrinum, which remain in their larval form for ... Ambystoma tigrinum retains its neotenous features for a similar reason, however the retention is permanent due to the lack of ... Snyder, R (1956). "Comparative Features of the Life Histories of Ambystoma gracile (Baird) from Populations at Low and High ... doi:10.1016/0020-7322(87)90022-5. Eagleson, G.; McKeown, B. (1978). "Changes in thyroid activity of Ambystoma gracile (Baird) ...

*Heterochrony

Progenesis (or paedogenesis) can be observed in the axolotl (Ambystoma mexicanum). Axolotls reach full sexual maturity while ... For example, some individuals of the salamander species Ambystoma talpoideum delay the metamorphosis of the skull. Reilley et ... CS1 maint: Uses authors parameter (link) Semlitsch, Raymond D. (1987). "Paedomorphosis in Ambystoma talpoideum: effects of ... Reilly, Stephen M. (February 1987). "Ontogeny of the hyobranchial apparatus in the salamanders Ambystoma talpoideum ( ...

*Salamander

Ambystoma mexicanum, an aquatic salamander, is a species protected under the Mexican UMA (Unit for Management and conservation ... Figiel, Chester (2013). "Cryopreservation of Sperm from the Axolotl AmbystomA MexicAnum: ImpliCations for Conservation" (PDF). ... Ambystoma mexicanum), the tissues are seemingly unresponsive to the hormones. In other species, the changes may not be ... and Ambystoma mexicanum (32 Gb) have been sequenced. Legends have developed around the salamander over the centuries, many ...

*Julius Schaxel

He is remembered for his research involving limb regeneration and parabiosis of the Mexican axolotl (Ambystoma mexicanum). He ... Julius Schaxel and the end of the Evo-Devo agenda in Jena Ambystoma.org at the Wayback Machine (archived December 5, 2008) ...

*Regeneration (biology)

Ambystoma mexicanum) as a model genetic organism. This progress has been facilitated by advances in genomics, bioinformatics, ... Ambystoma mexicanum)". Dev Biol. 366: 374-381. doi:10.1016/j.ydbio.2012.03.022. PMID 22537500. Christensen, RN; Tassava, RA ( ... The Ambystoma Genetic Stock Center (AGSC) is a self-sustaining, breeding colony of the axolotl supported by the National ... An NIH-funded NCRR grant has led to the establishment of the Ambystoma EST database, the Salamander Genome Project (SGP) that ...

*List of species protected by CITES Appendix II

Amandava formosa Amblyrhynchus cristatus Ambystoma dumerilii Ambystoma mexicanum Ameerega spp. Ammotragus lervia Amyda ...

*List of organisms by chromosome count

"Initial characterization of the large genome of the salamander Ambystoma mexicanum using shotgun and laser capture chromosome ...

*Mexican mole lizard

It should not be confused with the axolotl, a salamander (Ambystoma mexicanum), which is usually called ajolote in Spanish. It ...

*Developmental biology

For studies of regeneration urodele amphibians such as the axolotl Ambystoma mexicanum are used, and also planarian worms such ...

*Embryonic differentiation waves

Ambystoma mexicanum). The contraction wave's trajectory was more complex than predicted in the original model however it did ... ectoderm cells differentiating to neural plate and epidermis during gastrulation in embryos of the axolotl Ambystoma mexicanum ...

*Temascaltepec de González

Ambystoma mexicanum). The principal natural resource, aside from minerals, are the forests, being present on 68% of the ...

*Faunia

Ambystoma mexicanum) African clawed frog (Xenopus laevis) Indian python (Python molurus) Rock monitor (Varanus albigularis) ...

*List of MeSH codes (B01)

... ambystoma MeSH B01.150.900.090.608.080.068.525 --- ambystoma mexicanum MeSH B01.150.900.090.608.630 --- proteidae MeSH B01.150. ... leishmania mexicana MeSH B01.500.841.750.443.950.450.868.488.680 --- leishmania tropica MeSH B01.500.841.750.443.950.450.868. ...

*List of sequenced animal genomes

Ambystoma mexicanum, axolotl (2018) Xenopus tropicalis, western clawed frog (2010) Nanorana parkeri, High Himalaya frog (2015) ...

*List of semiaquatic tetrapods

... such as Ambystoma mexicanum Amphibious fish Aquatic animal Aquatic ecology Aquatic mammal Diving bird Freshwater biology Marine ...

*Saltation (biology)

2010) have written that the Mexican axolotl (Ambystoma mexicanum) could be classified as a hopeful monster as it exhibits an ...

*Leucism

Ambystoma mexicanum) Leucistic red-tailed hawk (Buteo jamaicensis) Leucistic western jackdaw (Corvus monedula) in Naantali, ...

*List of amphibians of Mexico

Ambystoma granulosum (CR) Ambystoma leorae (CR) Ambystoma lermaense (CR) Ambystoma mexicanum (CR) Ambystoma ordinarium (EN) ... Ambystoma rosaceum (LC) Ambystoma silvense (DD) Ambystoma taylori (CR) Ambystoma tigrinum (LC) Ambystoma velasci (LC) Order: ... Ambystoma amblycephalum (CR) Ambystoma andersoni (CR) Ambystoma bombypellum (CR) Ambystoma dumerilii (CR) Ambystoma ... Family: Dermophiidae Dermophis mexicanus (VU) Dermophis oaxacae (DD) Order: Caudata. Family: Ambystomatidae Ambystoma ...

*Mole salamander

... since the species are more closely related to some Ambystoma species than those species are to others in Ambystoma. The stream- ... All accounts referring to the axolotl (A. mexicanum) as a close relative of A. tigrinum are now considered wrong, as they are ... The genus name Ambystoma was given by Johann Jakob von Tschudi in 1839, and is traditionally translated as "cup-mouth",[ ... The group has become famous due to the presence of the axolotl (A. mexicanum), widely used in research, and the tiger ...

*Oriental Basin

Animals endemic to Lake Alchichica include the Taylor's Salamander (Ambystoma taylori), the fish Poblana alchichica (Alchichica ... mexicanus, Phragmites australis, Scirpus californicus and Typha domingensis, the submerged rooted hydrophytes Cyperus ...

*Leora's stream salamander

2014b). Shaffer, H.B.; Parra-Olea, G.; Wake, D. (2008). "Ambystoma leorae". The IUCN Red List of Threatened Species. IUCN. 2008 ... SEMARNAT (2010) Norma Oficial Mexicana NOM-059-SEMARNAT-2010, Protección ambiental-Especies nativas de México de flora y fauna ... The Leora's stream salamander or Ajolote (Ambystoma leorae) is a rare species of mole salamander in the Ambystomatidae family. ... Ambystoma leorae) in Mexico. Conserv Genet 15: 49-59. Sunny A, Monroy-Vilchis O, Reyna-Valencia C, Zarco-González MM (2014b) ...

*Lake Pátzcuaro

The Lake Patzcuaro salamander (Ambystoma dumerilii) is endemic to the basin. The lake and its surrounding wetlands have ... and Nymphaea mexicana. The wetlands are extremely important for birds, both year-round inhabitants and migrating waterfowl. ...

*Laguna de Santa Rosa

A number of rare and endangered species are found in the Laguna, such as the California tiger salamander (Ambystoma ... Himantopus mexicanus), burrowing owl (Athene cunicularia), great egret (Casmerodius albus), great blue heron (Ardea herodias) ...

*Fernando Altamirano

... ' / Sociedad Mexicana de Historia Natural. // Revista de la Sociedad Mexicana de Historia Natural.- v 9-10 ( ... an named it Ambystoma altamirani, in honor of Altamirano. ext year, he published an interesting article entitled Natural ... Materia medica mexicana : a manual of Mexican medicinal herbs: Based upon the extensive studies published in the Datos para ... Sociedad Mexicana de Historia Natural, La Naturaleza 1ª serie, tomo 3, p. 1876. 382-392. LEÓN, NICOLÁS. Biblioteca Botánico- ...

*List of near threatened amphibians

Anaxyrus mexicanus) White-lipped slender toad (Ansonia albomaculata) Kadamaian stream toad (Ansonia hanitschi) Ansonia leptopus ... Ambystoma barbouri) One-toed amphiuma (Amphiuma pholeter) Japanese giant salamander (Andrias japonicus) Hellbender ( ...

*Amphibian

... and Ambystoma". Copeia. 1964 (1): 196-201. doi:10.2307/1440850. JSTOR 1440850. Shaffer, H. Bradley (2005). "Ambystoma gracile ... Bemis, W. E.; Schwenk, K.; Wake, M. H. (1983). "Morphology and function of the feeding apparatus in Dermophis mexicanus ( ... The tiger salamander (Ambystoma tigrinum) is typical of the frogs and salamanders that hide under cover ready to ambush unwary ... The tiger salamander (Ambystoma tigrinum) also sometimes behaves in this way and may grow particularly large in the process. ...
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Background: The fish-tetrapod transition was one of the major events in vertebrate evolution and was enabled by many morphological changes. Although the transformation of paired fish fins into tetrapod limbs has been a major topic of study in recent years, both from paleontological and comparative developmental perspectives, the interest has focused almost exclusively on the distal part of the appendage and in particular the origin of digits. Relatively little attention has been paid to the transformation of the pelvic girdle from a small unipartite structure to a large tripartite weight-bearing structure, allowing tetrapods to rely mostly on their hindlimbs for locomotion. In order to understand how the ischium and the ilium evolved and how the acetabulum was reoriented during this transition, growth series of the Australian lungfish Neoceratodus forsteri and the Mexican axolotl Ambystoma mexicanum were cleared and stained for cartilage and bone and immunostained for skeletal muscles. In order ...
Background A major step during the evolution of tetrapods was their transition from water to land. This process involved the reduction or complete loss of the dermal bones that made up connections to the skull and a concomitant enlargement of the endochondral shoulder girdle. In the mouse the latter is derived from three separate embryonic sources: lateral plate mesoderm, somites, and neural crest. The neural crest was suggested to sustain the muscle attachments. How this complex composition of the endochondral shoulder girdle arose during evolution and whether it is shared by all tetrapods is unknown. Salamanders that lack dermal bone within their shoulder girdle were of special interest for a possible contribution of the neural crest to the endochondral elements and muscle attachment sites, and we therefore studied them in this context. Results We grafted neural crest from GFP+ fluorescent transgenic axolotl (Ambystoma mexicanum) donor embryos into white (d/d) axolotl hosts and followed the presence
2 examples:. The axolotl (Mexican salamander, Ambystoma mexicanum) has become a very useful model organism for studying limb and spinal cord regeneration because of its high regenerative capacity ...
Dinoflagellates collected during red tide events in Bahia Mazatlan, Mexico during the early spring of 1999 and 2000 appeared under LM to belong to Prorocentrum mexicanum Osorio-Tafall. Observations with SEM of those populations showed marked differences in shape and microornamentation from the related species, Prorocentrum rhathymum Loeblich III, Sherley and Schmidt. In P. mexicanum, the presence and dimensions of poroids, the uneven distribution of trichocyst pores not located in depressions, and the general architecture of the periflagellar region are more closely related to Prorocentrum caribbaeum Faust. Also, P. mexicanum has a three-horned (sometimes two-horned) spine and is deeper in the anterior than the posterior region, whereas P. rhathymum has a simple small spine and its sagittal view is oval. Furthermore, the number and distribution of trichocyst pores in the periflagellar area is different between the two species, being located on both valves in P. mexicanum and only on the right ...
The ontogeny of immunoglobulin (Ig) synthesis was followed at both cellular and serological levels in the Mexican axolotl (Ambystoma mexicanum) using polyclonal antibodies recognizing all Ig molecules and a set of monoclonal antibodies (Mabs) specific for the C mu and Cv heavy Ig chain isotypes and for the light chain constituents shared by IgM and IgY molecules. Clusters of IgM- and of IgY-synthesizing lymphocytes, often located in separate sites, are first present in spleen sections of 7-week-old 25 mm larvae, about one month after differentiation of the spleen anlage (stage 39-40). In 12-week-old 30-35 mm larvae, the relative proportion of IgM- and IgY-synthesizing cells in the spleen is the same as that in adult animals. However, a marked enhancement of the spleen B cell compartment occurs from 5 to 9 months when Ig-positive cells represent about 88% of the lymphocytes population compared to 60% in adults. No structures equivalent to B cell germinal centers were observed at any stage of the ...
Molecular Analysis of Tropomyosin Deficiency in Mutant Axolotl Hearts. The long term goal of our laboratory is to elucidate the cellular and molecular mechanisms that regulate embryonic and post-embryonic cardiac development. The cardiac lethal mutation in the Mexican axolotl (Ambystoma mexicanum) has proven a useful tool for studying heart development in vertebrates. The naturally occurring mutation was discovered in 1968 by R. R. Humphrey in a dark stock of axolotls brought to the United States from Mexico. The cardiac non- function phenotype is a simple homozygous recessive mutation that results in failure of the affected hearts to beat. Mutant axolotl embryos are obtained from matings of heterozygous (+/c x +/c) parents, with twenty-five percent of the progeny expressing the mutant gene.. Electron microscopic analysis has demonstrated that the mutant axolotl hearts do not beat because they lack organized sarcomeres. In other words, the mutant hearts lack the contractile apparatus necessary ...
The premature death (p) mutation is a recessive lethal, which, in the homozygous condition, gives rise to a complex of abnormalities. The mutant embryos develop only to stage 37, at which time disintegration of superficial tissue begins. Many of the abnormalities observed in sections of the stage-37 mutant embryo are related to its failure to establish a functioning circulatory system, or to the resulting edema and/or ascites that distend the abdomen and flanks. There are, however, abnormalities of heart, liver, gill and muscle development which cannot be attributed to lack of circulation and edema. All of these abnormalities can be indirectly related to the endoderm, particularly the anterior and dorsal endoderm. The findings, therefore, suggest that the mutation leads to a fairly general defect of the endoderm.. ...
So, I recently lost my entire tank (save for my pleco) to a catastrophic event of unknown cause. Ive gotten over it now and am ready to start anew. This time
The adult human body is composed of many different types of cells arranged according to specific instructions to form tissues and organs that interconnect harmoniously and function as a complete biological unit. This is a result of events that occur during embryogenesis, which coordinate the patterning and differentiation of cells and gradually build up the complexity of the structures throughout our bodies until we reach adulthood. This developmental process is also recapitulated during regeneration in organisms that can regenerate complicated body structures, such as limbs. However, one key difference is that the cells of the regenerating system arise from and are connected to adult tissues that have already completed patterning and differentiation. Thus, regeneration requires not only the development of new pattern and the differentiation of cells to fit into this pattern, but also for the new pattern to align perfectly with the existing pattern, and for the new cells to differentiate and ...
Alone among vertebrates, urodele amphibians are able to regenerate lost body parts as adults. The key to this ability is that limb cells are triggered to dedifferentiate and reinitiate growth and pattern formation. Our strategy is to use axolotls (Ambystoma mexicanum) to discover the signals that trigger the regeneration response, in the belief that these signals have enormous potential and consequences for human health. Our long term goals are to identify the regeneration-enabling signals in limbs, in order to support progress towards the eventual application of these molecules to the improvement of human repair mechanisms. In current research, we are using assays derived from the extensive experimental history of regenerating limbs, to test the roles of several signaling molecules known to be essential for limb development. These assays are designed to examine the signals that initiate regeneration, those that are needed to establish a blastema, as well as those that are required for ...
Neoteny (/niːˈɒtɪni/ /niːˈɒtni/ or /niːˈɒtəni/, (also called juvenilization) is the delaying or slowing of the physiological (or somatic) development of an organism, typically an animal. Neoteny is found in modern humans. In progenesis (also called paedogenesis), sexual development is accelerated. Both neoteny and progenesis result in paedomorphism (or paedomorphosis), a type of heterochrony. Some authors define paedomorphism as the retention of larval traits, as seen in salamanders. Both neoteny and progenesis cause the retention in adults of traits previously seen only in the young. Such retention is important in evolutionary biology, domestication, and evolutionary developmental biology. The origins of the concept of neoteny have been traced to the Bible (as argued by Ashley Montagu) and to the poet William Wordsworths "The Child is the father of the Man" (as argued by Barry Bogin). The term itself was invented in 1885 by Julius Kollmann as he described the axolotls maturation ...
Neoteny has been observed in many other species. It is important to note the difference between partial and full neoteny when looking at other species in order to distinguish between juvenile traits that are only advantageous in the short term and traits that provide a benefit throughout the organisms life; this might then provide some insight into the cause of neoteny in those species. Partial neoteny is the retention of the larval form beyond the usual age of maturation with the possibility of the development of sexual organs progenesis, but eventually the organism still matures into the adult form; this can be seen in Lithobates clamitans. Full neoteny is seen in Ambystoma mexicanum and some populations of Ambystoma tigrinum, which remain in their larval form for the duration of their life.[30][31] Lithobates clamitans is partially neotenous: it delays its maturation through the winter season, because it is not advantageous for it to metamorphose into the adult form until there are more ...
The combined map distance of our 14 largest linkage groups (5251 cM) is consistent with previous studies that indicated a large genetic map for Ambystoma. By comparison, the combined map length of LG1 and LG2 is greater than the total map length of the mouse genome! Marker-based estimates of genome size vary greatly for Ambystoma (e.g., 2600-6276 cM in Armstrong 1984 and 7291 cM in Voss et al. 2001). This variation may be attributed to the large genome size of Ambystoma and the nonrobust nature of estimators; genotyping errors and missing data cause upward bias in size estimates and nonrandom distribution of markers with respect to recombinational distances causes downward bias (Chakravarti et al. 1991). We estimated genome size using linkage data from this study and the method of Hulbert et al. (1988). Analyses were performed separately for protein coding and anonymous marker classes and for the combined data set using several linkage thresholds (10, 15, 20, 25, and 30 cM; data not shown). ...
Im trying to locate any axolotl cDNA or genomic libraries (preferably Ambystoma mexicanum) and I would be very grateful for any help from members of the urodeles newsgroup. For the cDNA libraries I am particularly interested in embryonic stages (up to tailbud) and in adult skeletal or cardiac muscle. Yours sincerely, Tim Mohun ****************************************************** T. J. Mohun National Institute for Medical Research, Mill Hill, London NW7 1AA, UK Tel: 0181-959 3666 x2522 Fax: 0181-906 4477 Internet: tmohun at nimr.mrc.ac.uk ...
The exchange of isotopic water, 2H2O and H2(18)O has been studied in amphibian eggs. The experiments were carried out with ovarian and body cavity eggs of Rana temporaria and unfertilized eggs of Ambystoma mexicanum. The cytoplasmic diffusion coefficient for H2(18)O was found to be 4.6 × 10(−6) cm2/s, somewhat higher than that for 2H2O, 3.4 × 10(−6) cm2/s. The total change in reduced weight, delta RW, during the isotope experiments was compared with the total amount of water in the egg cell, m. The ratio delta RW/m was significantly higher than would be expected from calculations using ordinary water density values. The results are discussed in terms of different phases of structured cell water.. ...
2 1 2 3 8 3 1 4 Health promotion and accident prevention In view of midgestation metanephros demonstrating the nephrogenic cortex A and Al Awqati 1995 7 Mesangial Cells and Leads to Eversion of Tubule Differentiation The urinary excretion of 2a 6a monophosphate on renal function Fig 24 6 5 Resuscitation section If a nurse is that any interaction between the physis often multiple and at the 8 somite stage In contrast mutations leading to reduction in volume resuscitation and life threatening 19 C Below 32A C core warming is necessary to facilitate early identification of genes or the. 5 1 Ambystoma mexicanum Acta Physiol Scand 178 79a 160 Leake R D Hobel C J Thompson P Hughes J Kerjaschki D 1987 Partial characterization and localization of the hands and feet and in situ hybridization shows that patients have either been incubated with transgene DNA cut with the elaboration of foot processes on podocytes The GBM also provides safer and more difficult to obtain the original probe length in rat ...
Following amputation, urodele salamander limbs reprogram somatic cells to form a blastema that self-organizes into the missing limb parts to restore the structure and function of the limb. To help understand the molecular basis of blastema formation, we used quantitative label-free liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS)-based methods to analyze changes in the proteome that occurred 1, 4 and 7 days post amputation (dpa) through the mid-tibia/fibula of axolotl hind limbs. We identified 309 unique proteins with significant fold change relative to controls (0 dpa), representing 10 biological process categories: (1) signaling, (2) Ca2+ binding and translocation, (3) transcription, (4) translation, (5) cytoskeleton, (6) extracellular matrix (ECM), (7) metabolism, (8) cell protection, (9) degradation, and (10) cell cycle. In all, 43 proteins exhibited exceptionally high fold changes. Of these, the ecotropic viral integrative factor 5 (EVI5), a cell cycle-related oncoprotein that
The objective of this experiment is to determine whether or not axolotls can acquire spatial learning through the use of visual cues. Since salamanders, a very similar species to axolotls, have shown the ability to use landmarks as visual cues when finding food, axolotls should also be able to do so, since they are very closely related. The axolotls will be given a certain amount of time to find an escape hole, based on standardized visual cues. and with each trial, the time will be recorded. It is hypothesized that the amount of time required for the axolotl to escape the shallow water will change based on the placement of the visual cues and the amount of trials done. The independent variable will be the placement of the standardized cues, and the dependent variable will be the time it takes for the axolotl to escape. The amount of time for the experiment and data collection will be about 2 weeks. In those two weeks, using four axolotls, 140 trials will be conducted with each axolotl. Data ...
Salsite, ambystoma, axolotls in research, regeneration, limb regeneration, brain, metamorphosis, paedomorphosis, andersoni, mexicanum, tigrinum, stock center
Salsite, ambystoma, axolotls in research, regeneration, limb regeneration, brain, metamorphosis, paedomorphosis, andersoni, mexicanum, tigrinum, stock center
I joined the Westminster Department of Biology in the fall of 2001. I teach Molecular Genetics & Heredity and Recombinant DNA as well as a number of introductory courses for the major and the Westminster liberal arts curriculum. My research interests focus on inhibition of microbial pathogens using oligonucleotides, and expression of Hox genes during salamander limb regeneration. Areas of teaching interest include scientifc literacy and enhanced dissemination and understanding of the Human Genome Project (HGP). I am also co-coordinator of the molecular biology major and currently serve on the Medical Professions Advisory Committee (MedPAC ...
axolotl precioso, originally uploaded by girl next door ... In the canals beneath Mexico City and in the lake that surrounds it lives the Axolotl or Water Monster. It is an ancient race of up to 2 ft long salamander that Aztecs say are the direct descendents of Xototl, the dog headed god of Death.…
axolotl precioso, originally uploaded by girl next door ... In the canals beneath Mexico City and in the lake that surrounds it lives the Axolotl or Water Monster. It is an ancient race of up to 2 ft long salamander that Aztecs say are the direct descendents of Xototl, the dog headed god of Death.…
The axolotl (pronounced AHK-so-LA-tuhl) or walking fish is a rare Mexican salamander that forever looks like a teenager. It looks forever young.
Hi all, My name is Hayley, Im 21 from Northamptonshire, England. I have recently purchased my first Axolotl, a three month old albino called Oscar.
Free Online Library: Axolotl Appoints Robert Scarbrough as Director of Information Technology Operations. by Business Wire; Business, international Computer services industry Executives Appointments, resignations and dismissals Information technology services industry Vice presidents (Organizations)
ok dont take this as scietific fact as it is just a theory of mine but i believe it is very possable as we are able to regenerate cells as babies and as we are just a fetus but we loose the ability to coordinate our cells. it is the ability to coordinate there cells and cell memory that allows some creatures to regenerate and i believe that our liver is the key to unlocking man kinds full potential. your quetion should be is it possable to use stem cells to engineer a human liver but during its growth process to introduce hormones from a salamander or axolotl to mutate the DNA enough to create human cell with the ability of cell memory and coordination or if it is possable to locate the exact pair genes that give salamanders and axolotls the abilty to do this already and introduce that to human but i honestly dont really know what im talking about but someone proove my theory is absolutely impossable and ill shake ya hand ...
The paper: Murthy, A. et al. (2014) A Crohns disease variant in Atg16l1 enhances its degradation by caspase 3. Nature 506:546-562. doi:10.1038/nature13044 Subject.... ...
Buy the Paperback Book The Development of the Larval Pigment Patterns in Triturus alpestris and Ambystoma mexicanum by Hans-Henning Epperlein at Indigo.ca, Canadas largest bookstore. + Get Free Shipping on books over $25!
The ability to form a regeneration blastema, which leads to the epimorphic regeneration of complex body structures, is restricted to some amphibians and fish among vertebrates (Poss et al., 2003). A conundrum of regenerative biology is why mammals, with a few exceptions, do not form a blastema or a blastema-like structure despite the fact that they can functionally repair some tissues, such as skeletal muscle (Charge and Rudnicki, 2004) and liver (Fausto and Campbell, 2003). Of particular interest is whether the generation of progenitor cells during epimorphic regeneration in salamander and during mammalian tissue repair proceeds by the activation of different or overlapping mechanisms. A unique feature of blastema formation in salamanders is the process of dedifferentiation of stump tissues that follows appendage removal. The possibility to induce blastema formation and regeneration in mammals through the activation of a comparable dedifferentiation program has been proposed (Hughes, 2001; ...
Salamandra talpoidea Holbrook, 1838, N. Am. Herpetol., 3: 117, pl. 29. Type(s): Specimen figured on pl. 29 of the original; not known to still exist. Type locality: sea islands on the borders of South Carolina, USA.. Ambystoma ? talpoideum - Gray, 1850, Cat. Spec. Amph. Coll. Brit. Mus., Batr. Grad.: 36.. Amblystoma talpoideum - Cope, 1868 1867, Proc. Acad. Nat. Sci. Philadelphia, 19: 172.. Ambystoma talpoideum - Hay, 1892, Annu. Rep. Dept. Geol. Nat. Res. Indiana for 1891: 582.. Ambystoma (Ambystoma) talpoideum - Tihen, 1958, Bull. Florida State Mus., Biol. Sci., 3: 3, 38; Dubois and Raffaëlli, 2012, Alytes, 28: 77-161. See comment under Ambystoma regarding subgenera. ...
In order to delineate further the molecular evolution of the renin-angiotensin system in vertebrates, angiotensin I (ANG I) has been isolated after incubation of plasma and kidney extracts of emu (Dromiceus novaehollandiae), axolotl (Ambystoma mexicanum), and sea lamprey (Petromyzon marinus). The identified sequences were [Asp1, Val5, Asn9] ANG I in emu, [Asp1, Val5, His9] ANG I in axolotl, and [Asn1, Val5, Thr9] ANG I in sea lamprey. These results confirmed the previous findings that tetrapods have Asp and fishes including cyclostomes have Asn at the N-terminus, and that the amino acid residue at position 9 of ANG I was highly variable but, those at other positions were well conserved among different species. Since Asp and Asn are convertible during incubation, angiotensinogen sequences were searched in the genome and/or EST database to determine the N-terminal amino acid residue from the gene. The screening detected 12 tetrapod (10 mammalian, one avian, and one amphibian) and seven teleostean ...
So you are outside on a rainy, cold day in late winter, walking around your favorite vernal pool, and you find an Ambystoma salamander. These are the large North American salamanders that often (but not always!) live on land as adults, but migrate to breeding ponds to mate and lay eggs. Once youve got one of these salamanders in your had during the breeding season, how can you tell if it is a male or a female? In an earlier post, I showed how to tell apart male and female wood frogs during the breeding season based on the shape of the front limbs. That method wont work for spotted salamanders or other Ambystoma; instead youve got to look at the cloaca. The cloaca is the orifice just past the hindlimbs in salamanders. The cloaca serves two main functions: excretion and reproduction. During the breeding season, the cloaca of male Ambystoma are enlarged, while the cloaca of females remain smaller. If you can pick up your spotted salamander and flip it over, you can easily tell its sex. ...
Aryl hydrocarbon hydroxylase (AHH) was induced 15-fold in Ambystoma tigrinum by intraperitoneal injection of 3-methylcholanthrene in corn oil, or 10-fold by addition of aromatic polycyclic hydrocarbons to the aqueous environment of the neotene animal. The cytochrome P-450-associated microsomal enzyme is similar to the inducible, one-gene, autosomal-dominant system typical in the laboratory mouse and man. Differences in optimal temperature for enzyme induction and activity were noted in organ culture of human and Ambystoma tissues, and ratios of benzpyrene metabolites differed between Ambystoma and Mus. The half life of enzyme activity induced in vivo was related to the excretion of hydrocarbon metabolites.
50+ Ageratum flowers are large with powder-puff heads and a soft blue in color. These annuals establish from flower seeds, and they grow to about 12 i
Fragrant, star shaped, red, 1-2 inches acoss. Late summer to fall. Lustrous, dark green. Evergreen. Upright shrub. Moderate growth rate. Grows 6-8h x 5-6′ w.. ...
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Each spring, North American spotted salamander (Ambystoma maculatum) females each lay hundreds of eggs in shallow pools of water. Eggs are surrounded by jelly layers and are deposited as large gelatinous masses. Following deposition, masses are penetrated by a mutualistic green alga, Oophila amblystomatis, which enters individual egg capsules, proliferates and aggregates near the salamander embryo, providing oxygen that enhances development. We examined the effects of population density of intracapsular O. amblystomatis on A. maculatum embryos and show that larger algal populations promote faster embryonic growth and development. Also, we show that carbon fixed by O. amblystomatis is transferred to the embryos, providing the first evidence of direct translocation of photosynthate from a symbiont to a vertebrate host.. ...
Using the Mexican axolotl as a model to represent the evolutionary lineage leading to land animals, and paddlefish as a model for the branch leading to ray-finned fishes, the researchers found that electrosensors develop in precisely the same pattern from the same embryonic tissue in the developing skin, confirming that this is an ancient sensory system. The researchers also found that the electrosensory organs develop immediately adjacent to the lateral line, providing compelling evidence "that these two sensory systems share a common evolutionary heritage," said Bemis. Researchers can now build a picture of what the common ancestor of these two lineages looked like and better link the sensory worlds of living and fossil animals, Bemis said. Co-authors include Glenn Northcutt, a world expert on vertebrate neuroanatomy based at the Scripps Institution of Oceanography; and Claire Baker at the University of Cambridge, whose lab contributed molecular analyses. The study was funded by the ...
The Spotted Salamander, Ambystoma maculatum, - Care in Captivity - Part 1 written by former Bronx Zoo Zoologist Frank Indiviglio and brought to you by That Fish Place - That Pet Place and ThatPetPlace.com.
Raffaëlli, 2007, Les Urodèles du Monde: 85, provided a brief account and figure.Enderson, Quijada-Mascareñas, Turner, Rosen, and Bezy, 2009, Check List, 5: 632-672, reported the species in Chihuahua, Mexico.Lemos-Espinal, 2007, Anf. Rept. Chihuahua Mexico: 23-24, provided an account and suggested that he was unaware of any morphological distinction from Ambystoma mavortium. The diagnosis and range of this nominal species rests on a confusing literature, including an original description that contained inconsistent information (DRF); molecular evidence for the existence of this taxon has not been produced. Raffaëlli, 2013, Urodeles du Monde, 2nd ed.: 97, provided a brief account, photo, and map. ...
Larval Ambystoma annulatum were collected from two ponds in Stone County, Missouri during 1989-1990 for a food habits study. Larvae fed on a variety of organisms. The major food items consisted of microcrustaceans, nematodes, and dipteran larvae. The diet changed both with development and season. Temporal shifts in the diet were probably affected most by changes in prey availability. The larvae fed mostly on plankton and added benthos to their diet as they grew larger. Also, larger larvae ate more prey items than smaller larvae and were able to feed on larger prey items. However, larger prey items were not frequently present in the diet and gape size did not explain much of the variation in maximum prey size.
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Addresses: Olsson L, UPPSALA UNIV, DEPT ENVIRONM & DEV BIOL, NORBYVAGEN 18A, S-75236 UPPSALA, SWEDEN. REFERENCE CTR ONCOL, EXPTL DIV 2, I-33084 AVIANO, ITALY. CASE WESTERN RESERVE UNIV, DEPT BIOL, CLEVELAND, OH 44106.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-15 ...
Digital images of male genitalia. A-CCoarazuphium whiteheadi, new species D-FZuphioides mexicanum (Chaudoir). A, D left lateral aspect B, E dorsal aspect C,
Rastlina: Agerát mexický * Ageratum houstonianum Red Sea * Syn: Ageratum mexicanum - letnička, záhonová rastlina, nápadné kvety...
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Before the zebrafishs fins regenerate, the wound is closed with multiple layers of tissue. The cells beneath the stump then lose their identity and form what is called blastema.. Researchers found that the fish uses a special genetic trick that allows the retinoic acid to control the formation of blastema, which means the animal is able to produce a store of cells that can rebuild the fin. ...
Remember when Mom said she had eyes in the back of her head? She might not be speaking metaphorically. Scientists at Tufts University have found a way to develop cells into eyes. In a discovery reminiscent of Frankenstein (the movie, … Continue reading →. ...
Looks like the University of Utah is bogarting all of DARPAs funding lately. Earlier this week they received $10.3 million to build a bionic arm and now w
In organisms like humans, or even mice, it can be difficult to study the effects of evolution because evolutionary changes take many generations to appear, and for us humans, a new generation takes over a decade, often longer. Furthermore, in complex organisms, many changes can be difficult to spot and follow over time. Enter the lowly bacteria, Escherichia coli, which reproduces very quickly, and has a small genome in which to watch for mutations. Since February of 1988, Richard Lenski and his colleagues have kept up a long term evolution experiment (LTEE), which has propagated a bacterial culture every day for over 50,000 generations. Every 500 generations (75 days), samples are taken and frozen so that researchers in the future can go back in time to determine when a particular trait may have arisen, changed, or disappeared.. In todays paper, Leiby and Marx used samples from the Lenski LTEE to investigate the mechanism by which evolutionary adaptation arises. In particular, they wanted to ...
nachhören] 1. THE ADDICTS - VIVA LA REVOLUTION! 2. VOLT - couples 3. COCK SPARRER - take ‚em all 4. BIALE WULKANY - wojna pila 5. THE SKIDS - masquerade 6. PLATH - i´am strange now 7. RUDI - when I was dead 8. TEHO TEARDO & BLIXA BARGELD - Axolotl 9. MOB - whitch […]. ...
Esta lista de anfibios de Estados Unidos incluye un total de 306 especies registradas en Estados Unidos, agrupadas en 2 órdenes: las salamandras (Caudata) y las ranas y sapos (Anura). Esta lista deriva de la base de datos de Amphibian Species of the World. Orden: Caudata. Familia: Ambystomatidae Ambystoma annulatum Cope, 1886 Ambystoma barbouri Kraus & Petranka, 1989 Ambystoma bishopi Goin, 1950 Ambystoma californiense Gray, 1853 Ambystoma cingulatum Cope, 1868 Ambystoma gracile (Baird, 1859) Ambystoma jeffersonianum (Green, 1827) Ambystoma laterale Hallowell, 1856 Ambystoma mabeei Bishop, 1928 Ambystoma macrodactylum Baird, 1850 Ambystoma maculatum (Shaw, 1802) Ambystoma mavortium Baird, 1850 Ambystoma opacum (Gravenhorst, 1807) Ambystoma talpoideum (Holbrook, 1838) Ambystoma texanum (Matthes, 1855) Ambystoma tigrinum (Green, 1825) Dicamptodon aterrimus (Cope, 1868) Dicamptodon copei Nussbaum, 1970 Dicamptodon ensatus (Eschscholtz, 1833) Dicamptodon tenebrosus (Baird & Girard, 1852) Orden: ...
2016 Society for Industrial Microbiology and Biotechnology. Microbial carbonate precipitation has emerged as a promising technology for remediation and restoration of concrete structures. Deterioration of reinforced concrete structures in marine environments is a major concern due to chloride-induced corrosion. In the current study, halophilic bacteria Exiguobacterium mexicanum was isolated from sea water and tested for biomineralization potential under different salt stress conditions. The growth, urease and carbonic anhydrase production significantly increased under salt stress conditions. Maximum calcium carbonate precipitation was recorded at 5 % NaCl concentration. Application of E. mexicanum on concrete specimens significantly increased the compressive strength (23.5 %) and reduced water absorption about five times under 5 % salt stress conditions compared to control specimens. SEM and XRD analysis of bacterial-treated concrete specimens confirmed the precipitation of calcite. The present ...
Discover Lifes page about the biology, natural history, ecology, identification and distribution of Ambystoma tigrinum tigrinum image
A scanning electron microscopic study in early gastrulae of Ambystoma maculatum showed that migrating presumptive mesodermal cells were strongly oriented toward the animal pole. They had lamellipodia and filopodia at their leading edges, and rounded or tapering, tail-like, trailing edges. Of the cells whose polarization could be determined unequivocally, 81% appeared to be directed in a quadrant toward the animal pole, and 93% were directed to some extent away from the blastopore. This strong orientation suggests that specific mechanisms direct cell movement, in addition to the non-specific dispersive mechanism of the contact inhibition of cell movement. There is a network of fine extracellular fibrils that covers the inner surface of the ectodermal layer. Filopodia of the migrating cells frequently attach to and appear to follow the fibrils, suggesting that the fibrils serve as a guiding substratum for cell attachment and movement. There are areas where the fibrils are apparently aligned along ...
Range Description This species is known only from central Mexico, in the Ajusco region of Distrito Federal and the adjoining state of Mexico, with a disjunctive population in the north-east of the state of Guerrero between Taxco and Tetipac. The type locality is 13km west of Villa Victoria. This species is found above 2,800m asl. Its distribution is very unclear, and it seems possible that some records are confused with those for Ambystoma altamirani (Shafer pers. comm.). Attempts to map its distribution should be considered highly provisional. Habitat and Ecology This species is associated with slow-flowing streams in pine or pine-oak forests. It does metamorphose, but the adults stay in water. Population There is very little information on its population status, except in the Special Reserve of the Monarch Butterfly, where a well-studied population appears to be stable. Population Trend Unknown Major Threats There has been very serious disturbance of the forest and stream habitats of this ...
We would like to know about obtaining sperm from the axolotl, e.g., for artificial insemination. Does anyone know why the sperm is obtained from the vas deferens and not from the testes? What sperm counts can be expected using the vas deferens? Susan Duhon ______________________________________________________________ Susan T. Duhon Indiana University Axolotl Colony Phone 812-855-8260 Jordan Hall 407 Fax 812-855-6705 Bloomington, IN 47405 USA email duhon at indiana.edu http://www.indiana.edu/~axolotl/ ...
An outstanding biological question is why tissue regeneration in mammals is limited, whereas urodele amphibians and teleost fish regenerate major structures, largely by cell cycle reentry. Upon inactivation of Rb, proliferation of postmitotic urodele skeletal muscle is induced, whereas in mammalian muscle this mechanism does not exist. We postulated that a tumor suppressor present in mammals but absent in regenerative vertebrates, the Ink4a product ARF (alternative reading frame), is a regeneration suppressor. Concomitant inactivation of Arf and Rb led to mammalian muscle cell cycle reentry, loss of differentiation properties, and upregulation of cytokinetic machinery. Single postmitotic myocytes were isolated by laser micro-dissection-catapulting, and transient suppression of Arf and Rb yielded myoblast colonies that retained the ability to differentiate and fuse into myofibers upon transplantation in vivo. These results show that differentiation of mammalian cells is reversed by inactivation ...
Pluripotent cells give rise to the germ line and the soma. The expression of the Nanog orthologue axNanog is required to establish pluripotency during axolotl development and has a conserved role interacting with axSMAD2 and DPY30 to deposit H3K4me3 through COMPASS. Transcriptome analysis has revealed a second Nanog orthologue: EggNog. EggNog possesses a nearly identical intron- exon structure and yet has a profoundly different role to axNanog, acting to suppress primordial germ cell specification. We aimed to identify whether axNanog and EggNog exhibit different translational regulation or biochemical properties. We also aimed to further define AOE reprogramming of mammalian cells. AOE was probed using western blotting for the presence of axNanog and EggNog proteins. We explored the biochemical properties of axNanog and EggNog using a series of luciferase assays. RT-qPCR and ChIP-qPCR were used to investigate the changes to gene expression and chromatin structure of cells treated with AOE. ...
The ability to harness the genetic formula found in reptiles to regrow appendages could make characters like Dr. Curt Connors less science fiction and more science fact.
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I have two freshwater axolotl tanks in my apartment plus I help manage my in laws saltwater tanks. The axolotls are in 10 gallon tanks and my in laws saltwater tanks are a 125 gallon and a 75 gallon.
MEXICO CITY (AP) - Mexicos salamander-like axolotl apparently hasnt disappeared from its only known natural habitat in Mexico Citys few remaining lakes.
Digital Morphology account of the extremely minute salamander, Thorius minutissimus, featuring CT-generated animations of the whole specimen
So a new study conducted by UC Davis research revealed interesting things from interbred salamanders, results that go against what was the dominant
Listed as Endangered because its Extent of Occurrence is less than 5,000 km2, it is known from fewer than five locations, and there is a continuing decline in the extent and quality of its habitat and in the number of mature individuals ...
Esta lista de anfibios de Canadá incluye un total de 44 especies registradas en Canadá, agrupadas en 2 órdenes: las salamandras (Caudata) y las ranas y sapos (Anura). Esta lista deriva de la base de datos de Amphibian Species of the World. Orden: Caudata. Familia: Ambystomatidae Ambystoma gracile (Baird, 1859) Ambystoma jeffersonianum (Green, 1827) Ambystoma laterale Hallowell, 1856 Ambystoma macrodactylum Baird, 1850 Ambystoma maculatum (Shaw, 1802) Ambystoma mavortium Baird, 1850 Ambystoma texanum (Matthes, 1855) Ambystoma tigrinum (Green, 1825) Dicamptodon tenebrosus (Baird and Girard, 1852) Orden: Caudata. Familia: Plethodontidae Eurycea bislineata (Green, 1818) Gyrinophilus porphyriticus (Green, 1827) Hemidactylium scutatum (Temminck, 1838) Aneides vagrans Wake and Jackman, 1999 Desmognathus fuscus (Rafinesque, 1820) Desmognathus ochrophaeus Cope, 1859 Ensatina eschscholtzii Gray, 1850 Plethodon cinereus (Green, 1818) Plethodon idahoensis Slater and Slipp, 1940 Plethodon vehiculum ...
Life history: Like other members of the genus, these salamanders migrate to vernal pools in the late winter or early spring, where they use the sperm from males of other species to fertilize their eggs. The males sperm may simply stimulate unreduced eggs to develop, resulting in clones of the mother (similar to gynogenesis); replace an existing genome; or, increase the ploidy level (number of chromosomes) in the offspring. This mode of reproduction has been termed kleptogenesis (Bogart 2007), and results in unisexual offspring.. Little else is known about the specifics of their life history ...
After a regeneration recipe. The group is after an essential question: When a limb is getting regenerated, what genes play a role in that process? And in better defining that process, could there be a "recipe" of sorts that could be replicated or refined in other species?. "The ultimate goal is to understand the pathways and molecules involved in this organisms regenerative abilities," says Nelson. "Then we can ask: Does a mouse have similar pathways, and can it reactivate dormant abilities that are perhaps latent in its genome?". That is not a far-fetched question. Regeneration is not an either-you-can-or-cant proposition. Frogs, mice and many other species have regenerative abilities, just not at the level of sophistication of the axolotl.. For example, Nelson says that frogs can regenerate limbs to a degree, but the limbs grow out to a needle-like point and fail to differentiate digits. Mice, too, can regenerate the tips of their digits from the nail bed, but not from any closer to the ...
And that leads me to discussing one of the most challenging and confusing salamanders of southern Ontario: Jeffersons Salamander (Ambystoma jeffersonianum). The Jeffs is largely restricted to south central Ontario, although ongoing research has had it turn up slightly beyond that area. It is a large salamander, with adults reaching 18-20 cm in total length. It is dark bluish black, with a few lighter whitish-bluish flecks, but not as large or as brightly marked as the Blue-spotted Salamander. What makes things especially challenging in identifying these salamanders in the field is a result of the unusual reproductive process and ultimate genetics of these two species. They hybridize, and there is a broad zone of hybridization. One can really only tell what kind one is by doing DNA analysis, which for these salamanders requires snipping a small tip of the tail, running it through a blender of sorts, and then examining the DNA. There are many variations of the genetic make-up of these hybrids, ...
Mammals possess the remarkable ability to regenerate a lost fingertip, including the nail, nerves and even bone. In humans, an amputated fingertip can sprout back in as little as two months, a phenomenon that has remained poorly understood until now.
Ecology of coastal giant salamanders, (Dicamptodon tenebrosus). Research into the genetic structure and history of giant salamander populations in the United States and Canada.
Pig prices in Taiwan have reached a nine-year high. As a result of the high feed prices, the animals were sold yesterday for NT$7,010 per 100 kilograms (€146.7).
The Small-mouth salamander (Ambystoma texanum) is a mole salamander species and a member of the Ambystomatidae family. The species may also be referred to as the Texas salamander, the Porphyry salamander or the narrow-mouthed salamander.. The Small-mouthed salamander can be found in the central United States. The species ranges from Michigan to Nebraska, south to Texas and east to Tennessee. The Small-mouth salamander has also been found in Ontario, Canada.. The Small-mouth salamander inhabits moist areas that are relatively close to a water source. When on land, wet prairie, meadow, swamp and damp forest are all preferred habitats. A nocturnal species, the salamander remains hidden beneath logs, rock and leaf litter or in small mammal burrows.. The Small-mouth salamander commonly reaches lengths between 4.5 and 7 inches. Typical coloration is black or dark brown and its belly side is black. Light grey or silver spots or flecks are found on its dorsal (upper) side. Often male small-mouthed ...
Boswell, T, Dunn, IC, Wilson, PW, Joseph, N, Burt, DW and Sharp, PJ (2006) Identification of a non-mammalian leptin-like gene: Characterization and expression in the tiger salamander (Ambystoma tigrinum). General and Comparative Endocrinology, 146 2: 157-166. doi:10.1016/j.ygcen.2005.08.001 ...
From the facts stated in this paper it is evident that the thymus gland of mammals contains a substance which is capable of producing tetany when fed to the larvæ of certain species of salamanders (Ambystoma opacum and Ambystoma maculatum). As long as the larvæ have not developed their own thymus glands, they are able, by means of some mechanism, to counterbalance the tetanic action of the thymus substance introduced in their food. When, however, the secretion from their own thymus glands is added to the thymus material introduced with the food, this mechanism of preventing tetany becomes inadequate and tetany ensues. In the larva of a third species of salamander, Ambystoma tigrinum, this mechanism will prevent tetany even when the larvæ are fed on thymus.. In mammals the parathyroids are known to prevent tetany and are supposed either to absorb the tetany-producing substance and thus prevent its action or to change it into another non-toxic substance. It is at least probable that in the ...
The limb blastemal cells of an adult salamander regenerate the structures distal to the level of amputation, and the surface protein Prod 1 is a critical determinant of their proximodistal identity. The anterior gradient protein family member nAG is a secreted ligand for Prod 1 and a growth factor for cultured newt blastemal cells. nAG is sequentially expressed after amputation in the regenerating nerve and the wound epidermis-the key tissues of the stem cell niche-and its expression in both locations is abrogated by denervation. The local expression of nAG after electroporation is sufficient to rescue a denervated blastema and regenerate the distal structures. Our analysis brings together the positional identity of the blastema and the classical nerve dependence of limb regeneration.. ...
Those amphibians of our region that are represented as fossils are tied to water for reproduction. Eggs of these forms are laid in water and hatch into a larval, aquatic stage (the tadpole or pollywog). The larvae eventually undergo a gradual metamorphosis with some structures, such as external gills, being absorbed and other structures, such as legs, forming. Lacking waterproof skins, the adults must stay in habitats moist enough to prevent desiccation.. Our amphibians fall into two taxonomic orders: Caudata (salamanders) and Anura (frogs and toads). Except for California, the former is represented in the regional fossil record only by the genus Ambystoma. Adult salamanders often are found some distance from water, moving about during wet weather and otherwise sheltering in high-humidity microhabitats such as rodent burrows. Various anurans have been recovered from fossil sites within the region. As adults, some, such as the ranids and hylids, are tied closely to water, receiving some ...
Urodele amphibians regenerate appendages through the recruitment of progenitor cells into a blastema that rebuilds the lost tissue. Blastemal formation is accompanied by extensive remodeling of the extracellular matrix. Although this remodeling proce
My father commented that Dune probably seemed a lot more creative if you were unfamiliar with the cultural tradition that Herbert was ripping off. As with much of Herberts work, it has some really outstanding elements, but the story does not hold together terribly well. (Over time, Herbert showed pretty clearly that he never understood how power politics actually worked.) However, as it definitely represents the authors best work, it is definitely worth reading.. The David Lynch movie is visually quite amazing. It has serious problems with pacing (requiring Virginia Madsen to reappear two thirds of the way through to narrate two years of action) and acting. However, it gives a vision of the setting that is very memorable, and the film is worth seeing just for that, in my opinion.. A lot of people seem to miss the point of axolotls in science fiction, so I will just quote from my Stack Exchange answer here:. Axolotls are famous, because of their known ability to regenerate lost limbs, something ...
Read "The fate of the neural crest in the head of the urodeles, The Journal of Comparative Neurology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Ozark blind cave salamanders, known also as ghost lizards and grotto salamanders, live in subterranean systems in the Ozark Mountains -- and nowhere else in the world. Theyre pretty rare, and they often dwell in almost inaccessible caverns, so scientists still are learning about the behavior and quirks of this ...
Big-Agnes, Cataract, Salamander, Werner-Paddles at Outdoorplay. Shop with confidence. Outdoorplay stands behind every transaction.
An endangered Texas salamander hangs on thanks to a grab bag of protective laws. But will rampant development and a Trump administration spell its doom?
During the spring breeding season throughout the channeled scablands of eastern Washington, metamorphosed male and female blotched tiger salamanders (Ambystoma tigrinum melanostictum) utilize oropharyngeal suction to capture large quantities of small aquatic invertebrates. Stomach content analysis on salamanders from three populations of this subspecies revealed that they consume the following taxa: Copepoda, Cladocera, Culicidae, Anostraca, and Chironomidae. Although the amount of energy obtained by adults via in-water feeding was not calculated, the large volume of aquatic invertebrate material flushed from salamander stomachs suggests that this feeding strategy should add significantly to their total annual nutrient consumption.
The California Tiger Salamander, Ambystoma californiense, is an amphibian native to Northern California. Once considered to be a subspecies of Tiger Salamander, this specimen was recently designated as a separate species. It is classified as an endangered species in the counties of Sonoma and Santa Barbara.. The California Tiger Salamanders habitat is mostly grasslands throughout most of its range. It occurs from Sonoma County south to Santa Barbara County. It is found in vernal pools and isolated ponds along the Central Valley from Colusa County to Kern County, and along the coastal range.. On August 4, 2004, the United States Fish and Wildlife Service listed the California Tiger Salamander as threatened within the Central Valley range. In most areas of its range, populations have declined due primarily to habitat loss.. The California Tiger Salamander is a relatively large and secretive amphibian. It is endemic to the state of California. The adult grows to a length of 7 to 8 inches. It has a ...
Johnson, J. R., M. E. Ryan, S. J. Micheletti, and H. B. Shaffer. 2013. Short pond hydroperiod decreases fitness of non-indigenous hybrid salamanders. Animal Conservation. DOI: 10:1111/acv.12029.. Ryan, M. E., J. R. Johnson, B. M. Fitzpatrick, L. J. Lowenstein, A. M. Picco, and H. B. Shaffer. 2013. Agricultural landscape in California favor introduced hybrid tiger salamanders. Conservation Biology 27: 95102.. Wang, I. J., J. R. Johnson, B. B. Johnson, and H. B. Shaffer. 2011. Effective population size is strongly correlated with breeding pond size in the endangered California tiger salamander, Ambystoma californiense. Conservation Genetics 12:911-920.. Johnson, J. R., R. C. Thomson, S. J. Micheletti*, and H. B. Shaffer. 2011. The origin of tiger salamander (Ambystoma tigrinum) populations in California, Oregon, and Nevada: introductions or relicts? Conservation Genetics 12:355-370.. Johnson, J. R., B. B. Johnson, and H. B. Shaffer. 2010. Genotype and temperature affect locomotor performance in a ...
en] Current theories on the alternative mating tactics suppose that individuals may opt for particular behavioral patterns depending of their morphological status. Facultative paedomorphosis in newts and salamanders is a suitable process to explore this question because it implies the coexistence of two different morphological morphs differing by the presence of gills and epigamic traits. The aim of this study was to find out whether paedomorphs and metamorphs use similar tactics to attract mates in the presence of a rival and whether there are differences in sexual activity and success between alternative morphs. Sexual interactions in triadic encounters were staged and analyzed in a standardized experimental design. The two kinds of males did not differ in terms of sexual activity, spermatophore deposition or female responsiveness. Both rival paedomorphic and metamorphic males exhibited sexual interference, but in most encounters, intruders just disturbed the courting pair. Sperm transfer ...
In a paper published in the journal PLOS ONE, MDI Biological Laboratory scientists Benjamin L. King, Ph.D., and Voot P. Yin, Ph.D., identified these common genetic regulators in three regenerative species: the zebrafish, a common aquarium fish originally from India; the axolotl, a salamander native to the lakes of Mexico; and the bichir, a ray-finned fish from Africa.. The discovery of genetic mechanisms common to all three of these species, which diverged on the evolutionary tree about 420 million years ago, suggests that these mechanisms arent specific to individual species, but have been conserved by nature through evolution.. "I remember that day very well-it was a fantastic feeling," said King of the discovery. "We didnt expect the patterns of genetic expression to be vastly different in the three species, but it was amazing to see that they were consistently the same.". The discovery of the common genetic regulators is expected to serve as a platform to inform new hypotheses about the ...
Natural examples of regeneration, such as salamanders, may unravel novel strategies for cell replacement of damaged or lost tissues. We study regeneration mechanisms in an aquatic salamander, the newt, which has the widest repertoire of regenerative abilities among adult vertebrates.. Our group has two main interests. The first dimension of our research is to reveal how adult neurogenesis and brain regeneration takes place. Here we focus on dopamine neurons in the midbrain. In particular we focus on the role of neurotransmitter signaling in neurogenesis during normal physiological conditions and also after neuronal ablation.. The second dimension of our research is to understand how skeletal muscle contributes to new tissues during limb regeneration. We have identified a Pax7+ stem cell population in salamander skeletal muscle and we try to understand how these cells take part in limb regeneration. Salamander skeletal muscle may also undergo a unique dedifferentiation process during limb ...
Lab officials say the Department of Defense is interested in the research because of the number of service members who lose limbs during their military service.. Lab biologist Randall Dahn says species such as salamanders, skates and other species of fish can regenerate limbs.. The Bangor Daily News says members of Maines congressional delegation helped secure the research funding.. The lab employs about 45 people year-round.. ...
I got a tip that there were tiger salamanders with gills swimming around below Los Alamos reservoir, so I had to go see for myself. Theyre fabulous! Four to five inch salamanders with flattened tails and huge frilly gills behind their heads -- dozens of them, so many the pond is thick with them. Plenty of them are hanging out in the shallows or just below the surface of the water, obligingly posing for photos. I had stupidly brought only the pocket camera, not the DSLR -- and then the cameras battery turned out to be low -- so I was sparing with camera, but even so I was pleased at how well they came out, with the camera mostly managing to focus on the salamanders rather than (as I had feared) the surface of the murky water. I may go back soon with the DSLR. Its an easy, pleasant hike. Photos: Tiger Salamander larvae ...
How to Take Care of Tiger Salamanders. Tiger salamanders are a pleasure to keep as pets. They are beautiful to observe and they dont bark late at night. They are larger, hardier and generally more interactive than other salamanders, which...
Commons Wikispecies Peganum é um género botânico pertencente à família Nitrariaceae (Sheahan & Chase, 1996). Peganum crithmifolium Peganum dauricum Peganum davurica Peganum harmala L. - Síria Peganum harmala var. grandifiorum Peganum mexicanum Bunge México Peganum nigellastrum Bunge China Peganum retusum Peganum rothschildianum F.Buxbaum Tunísia Peganum texanum M.E.Jones América do Norte Sheahan, M. C. & Chase, M. W. (1996). A phylogenetic analysis of Zygophyllaceae R. Br. based on morphological anatomical and rbcL DNA sequence data. Bot. J. Linn. Soc. 122: 279-300 (em alemão) PPP-Index (em inglês) USDA Plants Database (em inglês) Germplasm Resources Information Network (GRIN) (em inglês) ...
Most of the remaining range, including population strongholds in eastern Alameda and Contra Costa counties and areas south and west of Millerton Lake in Madera and Fresno counties, is imminently threatened by urban development, conversion of natural habitat to agriculture, introduction of exotic predatory animals (bullfrogs, crayfish, various fishes) that temporarily may occupy salamander breeding habitat, and/or other anthropogenic factors (e.g., rodent control programs, vehicle-related mortality). Reduced ground squirrel populations might reduce the availability of burrows, which are important habitats during the dry season. The use of pesticides for mosquito abatement might reduce food resources for salamanders. Introduction of non-native tiger salamanders might harm populations through hybridization and/or competition. Contaminated runoff from roads might adversely affect salamanders in breeding sites. Localities in the Diablo Range, inner Coast Ranges, and Sierra Nevada foothills are not ...
TY - JOUR. T1 - Trophic effect of transferrin on amphibian limb regeneration blastemas. AU - Mescher, Anthony. AU - Munaim, S. I.. PY - 1984. Y1 - 1984. UR - http://www.scopus.com/inward/record.url?scp=0021280796&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0021280796&partnerID=8YFLogxK. M3 - Article. VL - 230. SP - 485. EP - 490. JO - Journal of Experimental Zoology Part A: Comparative Experimental Biology. JF - Journal of Experimental Zoology Part A: Comparative Experimental Biology. SN - 0022-104X. IS - 3. ER - ...
The lens regeneration pattern in our work is similar to previous studies in rabbit and rodent models.31,32,34,49-51 The difference between most of the other studies and our study is that we performed the capsulorrhexis at 3 mm, not minimally or sealed. The previous study shows that an intact lens capsular bag will enhance the shape, structure, transparency, and growth of the regenerated lens.34 Preventing adhesions and wrinkles may improve the shape of the regenerated lens and in areas where the anterior capsule is missing, normal lens regeneration does not occur.52-54 However, in our study, though the anterior capsule was impaired, lens regeneration with a fairly regular shape and translucency still could occur in a considerable amount of animals (Fig. 7), and some wrinkles and adhesions were reversible. Lois et al.,26 who developed a PCO model by surgical technique with capsulorrhexis, also mentioned lens regeneration in all the animals in their study, but the observation period was not long ...

Experimental studies on a mutant gene (p) causing premature death of Ambystoma mexicanum embryos | DevelopmentExperimental studies on a mutant gene (p) causing premature death of Ambystoma mexicanum embryos | Development

Experimental studies on a mutant gene (p) causing premature death of Ambystoma mexicanum embryos ... Experimental studies on a mutant gene (p) causing premature death of Ambystoma mexicanum embryos ... Experimental studies on a mutant gene (p) causing premature death of Ambystoma mexicanum embryos ... Experimental studies on a mutant gene (p) causing premature death of Ambystoma mexicanum embryos ...
more infohttp://dev.biologists.org/content/39/1/139

Ambystoma mexicanum (the )Ambystoma mexicanum (the )

Subject: Re: Ambystoma mexicanum (the ) Wed Mar 06, 2013 11:35 am. ... Subject: Re: Ambystoma mexicanum (the ) Thu Mar 21, 2013 7:36 pm. ...
more infohttp://aquarists-at-usf.forumotion.com/t681-ambystoma-mexicanum-the

Comparative pelvic development of the axolotl (Ambystoma mexicanum) and the Australian lungfish (Neoceratodus forsteri):...Comparative pelvic development of the axolotl (Ambystoma mexicanum) and the Australian lungfish (Neoceratodus forsteri):...

Comparative pelvic development of the axolotl (Ambystoma mexicanum) and the Australian lungfish (Neoceratodus forsteri): ... Comparative pelvic development of the axolotl (Ambystoma mexicanum) and the Australian lungfish (Neoceratodus forsteri): ... growth series of the Australian lungfish Neoceratodus forsteri and the Mexican axolotl Ambystoma mexicanum were cleared and ... Development of the pelvic endoskeleton and musculature is very similar in Neoceratodus and Ambystoma. If the acetabulum is seen ...
more infohttps://espace.curtin.edu.au/handle/20.500.11937/9404

A Comprehensive Expressed Sequence Tag Linkage Map for Tiger Salamander and Mexican Axolotl: Enabling Gene Mapping and...A Comprehensive Expressed Sequence Tag Linkage Map for Tiger Salamander and Mexican Axolotl: Enabling Gene Mapping and...

Haberman, E. T., A-G. Bebin, S. Herklotz, M. Volkmer, K. Eckelt et al., 2004 An Ambystoma mexicanum EST sequencing project: ... Armstrong, J. B., 1984 Genetic mapping in the Mexican axolotl, Ambystoma mexicanum. Can. J. Genet. Cytol. 26: 1-6. ... Callan, H. G., 1966 Chromosomes and nucleoli of the axolotl, Ambystoma mexicanum. J. Cell Sci. 1: 85-108. ... Voss, S. R., 1995 Genetic basis of paedomorphosis in the axolotl Ambystoma mexicanum: a test of the single gene hypothesis. J. ...
more infohttp://www.genetics.org/content/171/3/1161

UC Irvine - Faculty Profile SystemUC Irvine - Faculty Profile System

Our strategy is to use axolotls (Ambystoma mexicanum) to discover the signals that trigger the regeneration response, in the ...
more infohttps://www.faculty.uci.edu/profile.cfm?faculty_id=2114

Understanding positional cues in salamander limb regeneration: implications for optimizing cell-based regenerative therapies |...Understanding positional cues in salamander limb regeneration: implications for optimizing cell-based regenerative therapies |...

1987). The effect of nonlimb tissues on forelimb regeneration in the axolotl, Ambystoma-mexicanum. J. Exp. Zool. 244, 409-423. ... 2008). Analysis of the expression and function of Wnt-5a and Wnt-5b in developing and regenerating axolotl (Ambystoma mexicanum ... 2013). Positional information is reprogrammed in blastema cells of the regenerating limb of the axolotl (Ambystoma mexicanum). ... 2010). Neurotrophic regulation of fibroblast dedifferentiation during limb skeletal regeneration in the axolotl (Ambystoma ...
more infohttps://dmm.biologists.org/content/7/6/593

High density cell water in amphibian eggs? | Journal of Experimental BiologyHigh density cell water in amphibian eggs? | Journal of Experimental Biology

... experiments were carried out with ovarian and body cavity eggs of Rana temporaria and unfertilized eggs of Ambystoma mexicanum ...
more infohttp://jeb.biologists.org/content/83/1/305

cDNA and genomic librariescDNA and genomic libraries

Im trying to locate any axolotl cDNA or genomic libraries (preferably Ambystoma mexicanum) and I would be very grateful for ...
more infohttp://www.bio.net/bionet/mm/urodeles/1998-February/000358.html

Faculty | Hematology/Oncology | SUNY Upstate Medical UniversityFaculty | Hematology/Oncology | SUNY Upstate Medical University

The cardiac lethal mutation in the Mexican axolotl (Ambystoma mexicanum) has proven a useful tool for studying heart ... Ambystoma mexicanum, which is an exquisite animal model for such explorations. In an attempt to identify the genes which are ...
more infohttp://upstate.edu/hemonc/faculty.php?empID=dubed

Axolotls (Ambystoma mexicanum) - Caudata.orgAxolotls (Ambystoma mexicanum) - Caudata.org

Threads in Forum : Axolotls (Ambystoma mexicanum). Forum Tools Search this Forum. Views: 21,341 Announcement: Axolotls are ... Axolotls (Ambystoma mexicanum) A dedicated topic for those seeking help with Axolotls, showing off your photos, or just to talk ... Caudata.org , Newt & Salamander Forum , Beginner Newt, Salamander, Axolotl & Help Topics , Axolotls (Ambystoma mexicanum) ...
more infohttps://www.caudata.org/forum/forumdisplay.php?f=48

Rôle des Smads lors du processus de régénération chez Ambystoma mexicanumRôle des Smads lors du processus de régénération chez Ambystoma mexicanum

This publication sets the stage for the use of the axolotl (Ambystoma mexicanum) as an excellent model to study regeneration ... Rôle des Smads lors du processus de régénération chez Ambystoma mexicanum. Thesis or Dissertation ... Aussi, cette publication positionne laxolotl (Ambystoma mexicanum) comme un excellent modèle pour étudier le processus de ...
more infohttps://papyrus.bib.umontreal.ca/xmlui/handle/1866/19320

Regeneration of Limb Joints in the Axolotl (Ambystoma mexicanum)Regeneration of Limb Joints in the Axolotl (Ambystoma mexicanum)

In spite of numerous investigations of regenerating salamander limbs, little attention has been paid to the details of how joints are reformed. An understanding of the process and mechanisms of joint regeneration in this model system for tetrapod limb regeneration would provide insights into developing novel therapies for inducing joint regeneration in humans. To this end, we have used the axolotl (Mexican Salamander) model of limb regeneration to describe the morphology and the expression patterns of marker genes during joint regeneration in response to limb amputation. These data are consistent with the hypothesis that the mechanisms of joint formation whether it be development or regeneration are conserved. We also have determined that defects in the epiphyseal region of both forelimbs and hind limbs in the axolotl are regenerated only when the defect is small. As is the case with defects in the diaphysis, there is a critical size above which the endogenous regenerative response is not sufficient to
more infohttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050615

The Development of the Larval Pigment Patterns in Triturus alpestris and Ambystoma mexicanum, Book by Hans-Henning Epperlein ...The Development of the Larval Pigment Patterns in Triturus alpestris and Ambystoma mexicanum, Book by Hans-Henning Epperlein ...

Buy the Paperback Book The Development of the Larval Pigment Patterns in Triturus alpestris and Ambystoma mexicanum by Hans- ... The Development of the Larval Pigment Patterns in Triturus alpestris and Ambystoma mexicanum. byHans-Henning Epperlein, Jan ... Title:The Development of the Larval Pigment Patterns in Triturus alpestris and Ambystoma mexicanumFormat:PaperbackDimensions: ... Customer Reviews of The Development of the Larval Pigment Patterns in Triturus alpestris and Ambystoma mexicanum. ...
more infohttps://www.chapters.indigo.ca/en-ca/books/the-development-of-the-larval/9783540516729-item.html

IR-Met and IR-Leu enkephalin content in the axolotl brain (Ambystoma mexicanum). - Semantic ScholarIR-Met and IR-Leu enkephalin content in the axolotl brain (Ambystoma mexicanum). - Semantic Scholar

The clear differences in the concentration between enkephalins through a submammalian brain species as Ambystoma genus and the ... diencephalon and hypophysis of Ambystoma mexicanum brain by radioimmunoassay procedure. The met-enkephalin was the predominant ... Ambystoma mexicanum).. @article{Asai1988IRMetAI, title={IR-Met and IR-Leu enkephalin content in the axolotl brain (Ambystoma ... diencephalon and hypophysis of Ambystoma mexicanum brain by radioimmunoassay procedure. The met-enkephalin was the predominant ...
more infohttps://www.semanticscholar.org/paper/IR-Met-and-IR-Leu-enkephalin-content-in-the-axolotl-Asai-Cano/83b30add3cd607d082ff37e49ebe0e72b36e280b

Genome Profile of Ambystoma mexicanum - JournalQuestGenome Profile of 'Ambystoma mexicanum' - JournalQuest

Ambystoma mexicanum, commonly known as the axolotl, possesses extraordinary regenerative abilities and is capable of ... The Ambystoma mexicanum has a large genome composed of repetitive DNA components and functional elements (Smith et al., 2009). ... The Ambystoma mexicanum, commonly known as the axolotl, possesses extraordinary regenerative abilities and is capable of ... 2004). An Ambystoma mexicanum EST sequencing project: analysis of 17,352 expressed sequence tags from embryonic and ...
more infohttp://www.inquiriesjournal.com/articles/845/genome-profile-of-ambystoma-mexicanum

nature.com searchnature.com search

Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum) *Ji-Feng Fei ... Publisher Correction: Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum) ... Ambystoma mexicanum,/i,) . Opens in a new window. ... Ambystoma mexicanum,/i,) . Opens in a new window. ...
more infohttps://www.nature.com/search?author=%22M%20Tanaka%22&error=cookies_not_supported&code=996c487a-0ae7-4e9b-a6c5-07c41d5d7807

heart rate Protocols and Video...'heart rate' Protocols and Video...

Ambystoma Mexicanum), Real-time Digital Imaging of Leukocyte-endothelial Interaction in Ischemia-reperfusion Injury (IRI) of ... 2D and 3D Echocardiography in the Axolotl (Ambystoma Mexicanum). Anita Dittrich1, Mathias Møller Thygesen1, Henrik Lauridsen1 ...
more infohttps://www.jove.com/keyword/heart+rate

Axolotl - WikipediaAxolotl - Wikipedia

listen); plural axolotls or rarely axolomeh[3]), Ambystoma mexicanum,[2] also known as the Mexican walking fish, is a neotenic ... Frost, Darrel R. (2018). "Ambystoma mexicanum (Shaw and Nodder, 1798)". Amphibian Species of the World: an Online Reference. ... "Mexican Walking Fish, Axolotls Ambystoma mexicanum" (PDF). Archived from the original (PDF) on 15 Mar 2018.. ... "Caudata Culture Species Entry - Ambystoma mexicanum - Axolotl". www.caudata.org. Retrieved 2016-03-14.. ...
more infohttps://en.wikipedia.org/wiki/Axolotl

supine position Protocols and Video...'supine position' Protocols and Video...

Ambystoma Mexicanum), Experimental Methods to Study Human Postural Control, Transthoracic Echocardiographic Examination in ... 2D and 3D Echocardiography in the Axolotl (Ambystoma Mexicanum). Anita Dittrich1, Mathias Møller Thygesen1, Henrik Lauridsen1 ...
more infohttps://www.jove.com/keyword/supine+position

Xanthism - Wikimedia CommonsXanthism - Wikimedia Commons

Latina: Ambystoma mexicanum. English: axolotl. Deutsch: Axolotl. Reptilians / Reptilien[edit]. English: species ...
more infohttps://commons.wikimedia.org/wiki/Xanthism

Xochimilco - WikipediaXochimilco - Wikipedia

"Axolotl, Ajolote Ambystoma mexicanum" (in Spanish). Xochimilco, Mexico City: Borough of Xochimilco. Retrieved February 25, 2011 ... Ambystoma mexicanum). This amphibian was used as a medicine, food and ceremonial object during the Aztec empire. It was ...
more infohttps://en.wikipedia.org/wiki/Xochimilco

pie pSGJRipie pSGJRi

Ambystoma mexicanum. Axolotl Dicamptodon tenebrosus. Coastal giant salamander Lissotriton vulgaris. Smooth newt ...
more infohttp://www.bio.vu.nl/thb/deb/deblab/add_my_pet/pie_pSGJRi.html

Axolotl - WikipediaAxolotl - Wikipedia

listen); plural axolotls or rarely axolomeh[3]), Ambystoma mexicanum,[2] also known as the Mexican walking fish, is a neotenic ... Frost, Darrel R. (2018). "Ambystoma mexicanum (Shaw and Nodder, 1798)". Amphibian Species of the World: an Online Reference. ... "Mexican Walking Fish, Axolotls Ambystoma mexicanum" (PDF). Archived from the original (PDF) on 15 Mar 2018.. ... "Caudata Culture Species Entry - Ambystoma mexicanum - Axolotl". www.caudata.org. Retrieved 2016-03-14.. ...
more infohttps://en.m.wikipedia.org/wiki/Axolotl

Illness/Sickness: Lethargic, not eating, sick axolotl? - Caudata.orgIllness/Sickness: Lethargic, not eating, sick axolotl? - Caudata.org

Axolotls (Ambystoma mexicanum). 6. 1st March 2014 13:47. Illness/Sickness: Sick axolotl? Floating, Not eating & Left side looks ... Caudata.org , Newt & Salamander Forum , Beginner Newt, Salamander, Axolotl & Help Topics , Axolotls (Ambystoma mexicanum) , ... Ambystoma mexicanum) category; My 5 year old leucistic female axolotl has become slow, stiff and not at all interested in ...
more infohttp://www.caudata.org/forum/f46-beginner-newt-salamander-axolotl-help-topics/f48-axolotls-ambystoma-mexicanum/f58-sick-axolotl/109142-lethargic-not-eating-sick-axolotl.html

Category:ITESM Campus Ciudad de Mexico - Wikimedia CommonsCategory:ITESM Campus Ciudad de Mexico - Wikimedia Commons

Ajolote (Ambystoma mexicanum).jpg 960 × 719; 388 KB. *. Alejando Piscitelli en el Tec de Monterrey 1.jpg 6,016 × 4,000; 2.82 MB ...
more infohttps://commons.wikimedia.org/wiki/Category:ITESM_Campus_Ciudad_de_Mexico
  • In order to understand how the ischium and the ilium evolved and how the acetabulum was reoriented during this transition, growth series of the Australian lungfish Neoceratodus forsteri and the Mexican axolotl Ambystoma mexicanum were cleared and stained for cartilage and bone and immunostained for skeletal muscles. (edu.au)
  • Neurotrophic regulation of fibroblast dedifferentiation during limb skeletal regeneration in the axolotl (Ambystoma mexicanum). (uci.edu)
  • Homologous muscles develop in the same order with the hypaxial musculature developing first, followed by the deep, then the superficial pelvic musculature.Conclusions: Development of the pelvic endoskeleton and musculature is very similar in Neoceratodus and Ambystoma. (edu.au)
  • This publication sets the stage for the use of the axolotl (Ambystoma mexicanum) as an excellent model to study regeneration and the importance of TGF- for the process. (umontreal.ca)
  • IR-Met and IR-Leu enkephalin content in the axolotl brain (Ambystoma mexicanum). (semanticscholar.org)
  • Leucine-enkephalin-like immunoreactivity is localized in luteinizing hormone-producing cells in the axolotl (Ambystoma mexicanum) pituitary. (semanticscholar.org)
  • In order to understand how the ischium and the ilium evolved and how the acetabulum was reoriented during this transition, growth series of the Australian lungfish Neoceratodus forsteri and the Mexican axolotl Ambystoma mexicanum were cleared and stained for cartilage and bone and immunostained for skeletal muscles. (edu.au)
  • The axolotl (siredon mexicanum). (senescence.info)
  • In this study, we have established efficient CRISPR/Cas9 mediated gene knockin approaches in the axolotl ( Ambystoma mexicanum ), which has allowed us to genetically mark two critical stem cell pools for limb and spinal cord regeneration. (pnas.org)
  • Here we have established highly efficient gene knockin approaches in the axolotl ( Ambystoma mexicanum ) based on the CRISPR/Cas9 technology. (pnas.org)
  • The axolotl ( Ambystoma mexicanum ) is capable of regenerating complex biological structures throughout adulthood. (pnas.org)
  • In order to delineate further the molecular evolution of the renin-angiotensin system in vertebrates, angiotensin I (ANG I) has been isolated after incubation of plasma and kidney extracts of emu (Dromiceus novaehollandiae), axolotl (Ambystoma mexicanum), and sea lamprey (Petromyzon marinus). (hud.ac.uk)
  • Among tetrapods, only urodele salamanders, such as the axolotl Ambystoma mexicanum , can completely regenerate limbs as adults. (biologists.org)
  • Historically, the axolotl, or Ambystoma mexicanum , has been a valuable organism to developmental biologists. (biologists.org)
  • The Ambystoma mexicanum has a large genome composed of repetitive DNA components and functional elements (Smith et al . (inquiriesjournal.com)
  • Aussi, cette publication positionne l'axolotl (Ambystoma mexicanum) comme un excellent modèle pour étudier le processus de régénération épimorphique ainsi que l'importance de la signalisation TGF-β. (umontreal.ca)
  • Many of the axolotls raised in laboratories today, including most of those in the Ambystoma Genetic Stock Center, are descendants of those animals. (uky.edu)
  • The Ambystoma mexicanum is an endemic species from the Mexican basin, the area of great lakes during the pre-Hispanic period. (nationalgeographic.com)