Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.Expectorants: Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here.Bromhexine: A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p744)Guaifenesin: An expectorant that also has some muscle relaxing action. It is used in many cough preparations.Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)Pleurodynia, Epidemic: An acute, febrile, infectious disease generally occurring in epidemics. It is usually caused by coxsackieviruses B and sometimes by coxsackieviruses A; echoviruses; or other enteroviruses.Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)Prolactin: A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.Milk, HumanFeces: Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.Administration, Oral: The giving of drugs, chemicals, or other substances by mouth.Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)Pilot Projects: Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.Sodium Channels: Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.Bromine: A halogen with the atomic symbol Br, atomic number 36, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested.Pharmaceutical Preparations: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.Photography: Method of making images on a sensitized surface by exposure to light or other radiant energy.Respiratory Distress Syndrome, Adult: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.Respiratory Distress Syndrome, Newborn: A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.Respiration, Artificial: Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).Pulmonary Surfactants: Substances and drugs that lower the SURFACE TENSION of the mucoid layer lining the PULMONARY ALVEOLI.Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).Positive-Pressure Respiration: A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange.Chromatography, Reverse-Phase: A chromatography technique in which the stationary phase is composed of a non-polar substance with a polar mobile phase, in contrast to normal-phase chromatography in which the stationary phase is a polar substance with a non-polar mobile phase.Pseudoephedrine: A phenethylamine that is an isomer of EPHEDRINE which has less central nervous system effects and usage is mainly for respiratory tract decongestion.Tablets: Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)Dosage Forms: Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.Drug Stability: The chemical and physical integrity of a pharmaceutical product.Pharmaceutical Services, Online: Pharmacy services accessed via electronic means.Counterfeit Drugs: Drugs manufactured and sold with the intent to misrepresent its origin, authenticity, chemical composition, and or efficacy. Counterfeit drugs may contain inappropriate quantities of ingredients not listed on the label or package. In order to further deceive the consumer, the packaging, container, or labeling, may be inaccurate, incorrect, or fake.Legislation, Pharmacy: Laws and regulations, pertaining to the field of pharmacy, proposed for enactment or enacted by a legislative body.Pharmacies: Facilities for the preparation and dispensing of drugs.Drug and Narcotic Control: Control of drug and narcotic use by international agreement, or by institutional systems for handling prescribed drugs. This includes regulations concerned with the manufacturing, dispensing, approval (DRUG APPROVAL), and marketing of drugs.Glucosephosphate Dehydrogenase Deficiency: A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia.Glucosephosphate DehydrogenaseFavism: Hemolytic anemia due to the ingestion of fava beans or after inhalation of pollen from the Vicia fava plant by persons with glucose-6-phosphate dehydrogenase deficient erythrocytes.Glyceraldehyde-3-Phosphate Dehydrogenases: Enzymes that catalyze the dehydrogenation of GLYCERALDEHYDE 3-PHOSPHATE. Several types of glyceraldehyde-3-phosphate-dehydrogenase exist including phosphorylating and non-phosphorylating varieties and ones that transfer hydrogen to NADP and ones that transfer hydrogen to NAD.Mediterranean Islands: Scattered islands in the Mediterranean Sea. The chief islands are the Balearic Islands (belong to Spain; Majorca and Minorca are among these), Corsica (belongs to France), Crete (belongs to Greece), CYPRUS (a republic), the Cyclades, Dodecanese and Ionian Islands (belong to Greece), MALTA (a republic), Sardinia and SICILY (belong to Italy). (From Webster's New Geographical Dictionary, 1988, p747)Sodium Channel Blockers: A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.SemicarbazonesVoltage-Gated Sodium Channel Blockers: A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.Tetrodotoxin: An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order TETRAODONTIFORMES, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Manufactured Materials: Substances and materials manufactured for use in various technologies and industries and for domestic use.Industry: Any enterprise centered on the processing, assembly, production, or marketing of a line of products, services, commodities, or merchandise, in a particular field often named after its principal product. Examples include the automobile, fishing, music, publishing, insurance, and textile industries.Industrial Oils: Oils which are used in industrial or commercial applications.Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.EuropeDiet: Regular course of eating and drinking adopted by a person or animal.

Transferability of cephalothin to the alveolar cavity in thoroughbreds. (1/26)

Five Thoroughbreds were classified into 4 groups according to the administration method used for saline solution (saline), ambroxol, and cephalothin sodium (cephalothin). In group A, cephalothin was injected intravenously after oral administration of ambroxol. In group B, cephalothin was injected intravenously after oral administration of saline. Groups C and D were used as control groups. The dose of cephalothin or ambroxol was clinically administrated. Venous blood and bronchoalveolar lavage fluid (BALF) were sampled from each group. In groups A and B, cephalothin concentrations in plasma reached their maximum level 5 min after cephalothin administration and then declined over time. In plasma obtained from groups A and B, there were no significant differences in pharmacokinetic parameters (T1/2, Kel, Vd). By contrast, cephalothin concentrations in BALF reached their peak at 180 min after cephalothin administration in both groups A and B and maintained a relatively high level even after 300 min. These findings indicate that cephalothin requires a relatively long period of time to move from the blood stream to the alveolar cavity, but once transferred to the alveolar cavity, it is preserved for a long time. In groups A and B, cephalothin concentrations in BALF were approximately at the same level. However, in group A, total protein in BALF was lower at 60, 180, and 300 min than the other groups. Then, cephalothin concentration was adjusted to total protein in BALF. After adjustment to total protein in BALF, group A showed a concentration level of cephalothin approximately 1.5-fold higher than that of group B. This suggests that the transferability of cephalothin to the alveolar cavity improves as a result of the oral administration of ambroxol.  (+info)

Effect of early ambroxol treatment on lung functions in mechanically ventilated preterm newborns who subsequently developed a bronchopulmonary dysplasia (BPD). (2/26)

In a randomized trial in 102 preterm newborns with respiratory distress syndrome (RDS) it has been shown that early Ambroxol treatment (30 mg kg(-1) over the first 5 days) significantly reduces the incidence of RDS-associated complications [bronchopulmonary dysplasia (BPD), intraventricular haemorrhage, post-natal acquired pneumonia]. The aim of the present analysis was to investigate the effect of Ambroxol treatment on lung function in newborns who developed BPD. Respiratory function testing (RFT) was performed immediately after extubation and at day 28. Tidal volume (VT) and respiratory frequency (f) were measured during tidal breathing using the deadspace free flow-through technique. The lung mechanic parameter VT/maxPes was determined by measuring the maximal oesophageal pressure changes, maxPes, with a catheter tip pressure transducer. In the placebo group 36/50 infants were extubated within the first 28 days of life and 13/36 (36%) developed BPD. In the Ambroxol group 44/52 were extubated and 9/44 (20%) developed BPD. After extubation, RFT showed (i) no statistically significant difference in the ventilatory parameters of either treatment group, (ii) improved (P<0.05) lung mechanics (VT/maxPes) in Ambroxol group compared to controls (94+/-27 ml kPa(-1) vs. 8.1+/-2.6 ml kPa(-1)) and (iii) no statistically significant difference in lung function between infants with and without BPD. At day 28 we found (i) no effect of early Ambroxol treatment on lung functions, (ii) significantly (P < 0.05) higher f (58.5+/-11.7 min(-1) vs. 49.7+/-10.1 min(-1)) and significantly (P<0.01) lower V(T) (9.6+/-1.9 ml vs. 12.3+/-2.7 ml) and V(T)/maxPes (8.9+/-2.6 ml kPa(-1)] vs. 12.0+/-2.9 ml kPa(-1)) in infants with BPD compared to infants without and (iii) these differences are not influenced by early Ambroxol treatment. If the process of BPD development is induced, early Ambroxol treatment has no influence on impaired lung function at day 28.  (+info)

Effects of N-acetylcysteine and ambroxol on the production of IL-12 and IL-10 in human alveolar macrophages. (3/26)

BACKGROUND: N-acetylcysteine (NAC) and ambroxol (AMB) have recently been proposed as possible therapeutic agents in the treatment of pulmonary disorders. IL-12 plays an important role in host resistance to infection and the development of Th-1 cells. In contrast, IL-10 is involved in anti-inflammatory and immunoregulatory mechanisms. OBJECTIVE: We investigated the effects of NAC and AMB on secretions of IL-12 and IL-10 from human alveolar macrophages. METHODS: Alveolar macrophages were obtained from 7 healthy nonsmokers by bronchoalveolar lavage. The cells were first incubated with either NAC or AMB for 2 h and then cultured in lipopolysaccharide (LPS) solution for 24 h. IL-12 and IL-10 secretions were measured by ELISA. RESULT: Both NAC and AMB enhanced LPS-induced secretion of IL-12. NAC also enhanced LPS-induced IL-10 secretion, while AMB did not. The ratio IL-12/IL-10 secretion was increased by AMB, but NAC did not affect it. CONCLUSIONS: The results suggest that NAC enhances inflammatory and immune responses and prevents excessive responses reciprocally, through keeping local balance of IL-12 and IL-10 production in alveolar macrophages at inflammatory sites of bacterial pneumonia. AMB appears to strengthen inflammatory responses and cell-mediated immunity, facilitating the development of Th-1 cells, through shifting the local balance to IL-12 dominance.  (+info)

Depressant effect of ambroxol on stimulated functional responses and cell death in rat alveolar macrophages exposed to silica in vitro. (4/26)

The present study examined the effect of ambroxol on free radical production, granule enzyme release, and cell death in silica-activated rat alveolar macrophages. The action of ambroxol was assayed by measuring changes in the activities of protein kinase C (PKC) and tyrosine kinase (PTK) and in the intracellular calcium level. Ambroxol attenuated the production of superoxide, hydrogen peroxide, and nitric oxide and the release of acid phosphatase and lysozyme in macrophages activated by silica. Staurosporine, genistein, EGTA, and trifluoperazine inhibited the silica-induced free radical production and granule enzyme release. Silica induced the increase in PKC and PTK activities and the elevation of intracellular calcium level in macrophages, which was decreased by ambroxol. Silica induced a cell death and increased the caspase-3 activity in macrophages in a concentration-dependent manner. Ambroxol decreased the silica-induced cell viability loss in macrophages. The results show that ambroxol decreases the stimulated responses and cell death in rat alveolar macrophages exposed to silica, which may be accomplished by inhibition of activation processes, protein kinases, and calcium transport. The inhibitory effect of ambroxol on silica-induced cell death appears to provide the protective effect on pulmonary tissues against the toxic action of silica.  (+info)

Ambroxol suppresses influenza-virus proliferation in the mouse airway by increasing antiviral factor levels. (5/26)

The protective effect of ambroxol, a mucolytic agent which has antioxidant properties and stimulates the release of pulmonary surfactant, against influenza-virus proliferation in the airway was investigated in mice. Ambroxol or the vehicle was administered intraperitoneally twice a day for 5-7 days to mice shortly after intranasal infection with a lethal dose of influenza A/Aichi/68 (H3N2) virus, and the survival rate, virus titre and levels of factors regulating virus proliferation in the airway fluid were analysed. Ambroxol significantly suppressed virus multiplication and improved the survival rate of mice. The effect of ambroxol reached a peak at 10 mg x kg(-1) x day(-1), higher doses being less effective. Ambroxol stimulated the release of suppressors of influenza-virus multiplication, such as pulmonary surfactant, mucus protease inhibitor, immunoglobulin (Ig)-A and IgG, although it stimulated the release of a trypsin-type protease that potentiates virus proliferation. In addition, ambroxol transiently suppressed release of the cytokines, tumour necrosis factor-alpha, interferon-gamma and interleukin-12, into airway fluid. Although ambroxol had several negative effects on the host defence system, overall it strikingly increased the concentrations of suppressors of influenza-virus multiplication in the airway.  (+info)

Inhibition of tetrodotoxin (TTX)-resistant and TTX-sensitive neuronal Na(+) channels by the secretolytic ambroxol. (6/26)

Ambroxol has a long history for the treatment of airway diseases because of its beneficial effects on surfactant synthesis and mucus-modifying properties. Some findings, however, point to an additional effect on neuronal signal transduction: ambroxol can suppress reflexes such as the cough or the corneal reflex. The airways and the cornea are innervated by C-fibers, which express voltage-gated Na(+) channels with and without sensitivity to tetrodotoxin (TTX). In this study, we performed voltage-clamp experiments to investigate whether ambroxol affects these channel types. In rat dorsal root ganglia, TTX-resistant Na(+) currents were suppressed in a concentration-dependent manner with IC(50) values of 35.2 and 22.5 microM for tonic and phasic block, respectively. Depolarizing prepulses increased the potency of ambroxol, and steady-state inhibition curves were shifted to more negative values. The inhibition was not frequency-dependent. TTX-sensitive currents were inhibited with lower potency (approximately 50% inhibition with 100 microM). Recombinant rat brain IIA channels in Chinese hamster ovary cells were blocked with IC(50) values of 111.5 and 57.6 microM for tonic and phasic block, respectively; in contrast to TTX-resistant channels the block was frequency-dependent. Thus, ambroxol indeed blocks neuronal voltage-gated Na(+) channels, and TTX-resistant channels in sensory neurons were more sensitive than TTX-sensitive. Compared with known local anesthetics (e.g., lidocaine or benzocaine), the potency for Na(+) channel block was relatively high. A recent clinical trial has further confirmed that ambroxol relieved pain and was beneficial in patients who suffered from sore throat.  (+info)

Pulmonary alveolar proteinosis successfully treated with ambroxol. (7/26)

A 79-year-old woman was admitted to hospital due to a four-month history of a cough and dyspnea on exertion. Chest CT scans revealed ground glass opacity with thickened interlobular septa in both lungs. Bronchoalveolar lavage fluid (BALF) had milky appearance and revealed large acellular eosinophilic amorphous bodies positively stained with periodic acid-Schiff (PAS). Autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF) were present in sera and BALF from the patient. Ambroxol was started in a daily dose of 45 mg orally. Her oxygen saturation improved and abnormal shadows in CT scan disappeared 6 months after beginning the therapy.  (+info)

In vitro inhibition of human neutrophil histotoxicity by ambroxol: evidence for a multistep mechanism. (8/26)

Neutrophils are major culprits for the protease/antiprotease imbalance during various lung diseases, that is, chronic obstructive pulmonary disease, cystic fibrosis, idiopathic pulmonary fibrosis and adult respiratory distress syndrome. Thus, these cells are presently considered an ideal target for the pharmacologic control of tissue injury during these diseases. This study was planned in order to investigate if ambroxol and its precursor bromhexine are actually capable of preventing alpha-1-antitrypsin (A1AT) inactivation by stimulated neutrophils and possibly to look into the mechanisms underlying this event. Ambroxol inhibited the production of superoxide anion by activated neutrophils, whereas bromhexine had no inhibitory effect. Ambroxol decreased the production of hypochlorous acid (HOCl) from activated neutrophils with high efficiency, whereas bromhexine had a modest activity. Ambroxol and bromhexine were capable of limiting the chlorination of monochlorodimedon by HOCl, displaying the capacity of directly scavenging the oxidant. Ambroxol decreased the release of elastase and myeloperoxidase from activated neutrophils, whereas bromhexine was ineffective. Ambroxol prevented the A1AT inactivation by neutrophils, whereas bromhexine was completely ineffective. Among drugs currently available for in vivo use in humans, ambroxol is unique by virtue of its ability to prevent neutrophil-mediated A1AT inactivation via inhibition of HOCl production as well as HOCl scavenging. Also taking into account its capacity for curbing elastase release, the drug displays the potential to lessen the burden of oxidants/proteases and to increase the antiprotease shield at the site of inflammation. Thus, ambroxol appears to be a good candidate for raising attempts to develop new therapeutic histoprotective approaches to inflammatory bronchopulmonary diseases.  (+info)

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AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 uM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.
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Ambroxol secretolytic drug molecule. Also often used in treatment of soar throat. Atoms are represented as spheres with conventional colour coding: hydrogen (white), carbon (grey), oxygen (red), nitrogen (blue), bromine (brown). - Stock Image F011/3692
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Alkarex-PD information about active ingredients, pharmaceutical forms and doses by Symbiosis, Alkarex-PD indications, usages and related health products lists
Generics: Ambroxol, Form: SYRUP, Pack Size: 1, Brand name: COFCEL 100ML SYRUP, Manufacturer: ACEL PHARMA PVT LTD, Contains: Ambroxol 15 MG+Terbutaline 1.25 MG+Guaifenesin 50 MG+Menthol 2.5 MG, Drug ...
Different Asthma Phenotypes in Adult Asthma: Comparison of Allergic Asthma and Nonallergic Asthma Chih-Hao Chang, Horng-Chyuan Lin, Meng-Heng Hsieh, Guan-Yuan Chen, Fu-Tsai Chung, Chih-Teng Yu, Han-Pin Kuo Anti-inflammatory Activity and Mucolytic Effect of Ambroxol in Patients with Stable Chronic Bronchitis ─ A Preliminary Report Chien-Ming Chu, Chung-Chieh Yu, Huang-Ping Wu, Bor-Yiing Jiang, Jo-Chi Tseng, Chung-Ching Hua, Teng-Jen Yu, Yu-Chih Liu, Wen-Pin Shieh Spontaneous Remission in Goodpasture Syndrome and Relapse 5 Years Later - A Case Report Fang-Chuan Dai, Mei-Chin Wen, Jeng-Yuan Hsu, Gwan-Han Shen IgG4-Related Sclerosing Disease of the Lung ─ Case Report Chih-Heng Kuo, Wen-Hu Hsu, Yi-Chen Yeh Wegeners Granulomatosis with Tracheal Involvement and Severe Pulmonary Hemorrhage Hui-Wen Shih, Hou-Tai Chang, Cheng-Yu Chang, Shin-Lung Cheng Late Onset Non-Infectious Interstitial Lung Disease Following Bone Marrow Transplantation: A Case Report Mei-Ling Chen, Yung-Hsiang Hsu, En-Ting Chang
Specific respiratory drugs, Mucolytics, , All forms of tracheobronchitis, emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, bronchiectasis, bronchitis with bronchospasm asthma. During acute exacerbations of bronchitis it should be given with the appropriate antibiotic.
A consistent line of investigation proposes that fibromyalgia is a sympathetically maintained neuropathic pain syndrome. Dorsal root ganglia sodium channels may play a major role in fibromyalgia pain
Medicines With Alo Vera It was Europe who first started to use this drug together with diet and exercise with patients having a BMI of greater than 30. - bu
Hello-hello! Am căutat pentru băiețelul cel mare un sirop de tuse bun, mai bine de o lună. Odată cu intrarea în colectivitate am avut parte de mici răceli de care am scăpat relativ ușor însă tusea nu s-a lăsat doborâtă cu una cu două. A dat gata dragul de el două sticle de sirop, fără …. ...
Journal of Science and Pharmacy, Jan-Mar, 2004. "Analgesic activity of stem bark of Helicteresisora Linn." "HPTLC method for determination of Carvedilol from tablet formulation" "Validated HPTLC method for estimation of Desloratadine from tablet formulation" Journal of Science and Pharmacy, Jul. - Sept. 2005 "Analgesic activity of stem bark of Kigeliapinnata Linn." Journal of Science and Pharmacy, Jan. - Mar. 2006 "CNS depressant activity of stem bark of Kigeliapinnata Linn." Indian Journal of Natural Products, 22 (2) , 2006 "Antimicrobial activity of stem bark of Helicteresisora" Indian Journal of Natural Products, 22 (3), 2006 "Antimicrobial activity of stem bark of Kigeliapinnata" Journal of Pharmacy Research, 2009, 2(8), 1311-1312. Spectrophotometric determination of Ambroxol hydrochloride from bulk and Journal of Pharmacy Research, 2009, 2 (9), 1370-1372 Quantitative determination of β - sitosterol from stem bark of Helicteresisoralinn. Asian Journal of Pharmaceutical and Clinical Research ...
Manufacturer of Pharmaceutical Syrup - Deromine Syrup Essential Amino Acid, Ambroxol Hydrochloride Levosalbutamol and Guaiphenesin Syrup, Utrine Tonic Syrup and Cyproheptadine Hydrochloride and Tricholine Citrate Syrup offered by Deepar Pharmaceuticals Pvt Ltd, Jaipur, Rajasthan.
Wholesaler of Pharmaceutical Syrup - ENCYCLO ZYME-5G SYRUP, Calcium Carbonate & Vitamin D3 Suspension, Haematnic Syrup of Ferric Ammonium Eibate Folic Acid & Cyanocobalamin and Ambroxol Hydrochloride Guaiphenesin Terbutaline Sulphate & Menthol Syrup offered by Encyclo Healthcare, Hisar, Haryana.
ZYLIG LIFESCIENCES - Manufacturer, Distributor & Supplier of Syrups A COMPLETE DIGESTIVE ENZYME SYRUP,A COMPLETE LIVER RESTORATIVE,An herbal alkaliser syrup,Digestive Enzymes,Multivitamin & Body Flora Tablets,Cough Reliever Enriched With Honey & Tulsi,Ambroxol Hydrochloride 15Mg+ Guaiphenesin 50Mg+ Terbutaline 1.25 Mg + Menthol 2.5Mg/5Ml,Ofloxacin + Metronidazole banzoate + Simethicone,Parecetamol+Phenyl +Dipenhydramine +Caffien, India
DEVELOPMENT AND VALIDATION OF FIRST ORDER DERIVATIVE SPECTROSCOPIC METHOD FOR ESTIMATION OF OLOPATADINE HYDROCHLORIDE AND AMBROXOL HYDROCHLORIDE IN THEIR SYNTHETIC MIXTURE ...
Ambroxol hydrochloride and glucose infusions are used in the treatment of respiratory diseases which include tracheobronchitis, emphysema and others.
Mucoslovan, also known by its generic name of ambroxol hydrochloride, can cause mild gastrointestinal problems occasionally in some people, according to Drugs.com. Known as a mucolytic agent, this...
Wholesale Trader of Pharmaceutical Syrup - An Ayurvedic Blood Purifier Tonic, Levocetirizine Syrup, Levosalbutamol, Ambroxol HCI & Guaiphensin Syrup and Levocetirizine Dihydrochloride & Montelukast Oral Syrup offered by SOINSVIE PHARMACIA PRIVATE LIMITED, Panchkula, Haryana.
Ria Lifesciences Private Limited, Vashisht Park, New Delhi, Delhi - Established in 2012, we are Manufacturer of Amoxycillin 500 mg & Potassium Clavulanate 125 mg with Lactic Acid 60 Million Spores, Ambroxol HCI Levosulbactum Sulphate & Guaiphenesin Syrup, Multimineral Capsule, Pantoprazole Injection and Anti Infective Drugs & Medicines
Therapeutic segment: Cough & Cold Composition: LEVOSALBUTAMOL 1 MG + AMBROXOL 30 MG + GUAIPHENESIN 50 MG Packaging details: 100 ml Pet Bott [...]. ...
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Acti doxy, Actidox, Ambrodoxy, Ambroxol, Amermycin, Antodox, Apdox, Asidox, Asolmicina, Atridox, Bactidox, Bassado, Bidoxi, Bio-doxi, Biodoxi, Biomoxin, Bistor, Bronmycin, By-mycin, Calierdoxina, Ciclidoxan, Ciclonal, Clinofug d, Compomix, Cyclidox, Deoxymykoin, Docdoxycy, Dohixat, Doksiciklin, Doksin, Doksy, Doksycyklina, Doprovet, Doryx, Dosil, Dotur, Dovicin, Doxacil, Doxacin, Doxakne, Doxam, Doxat, Doxi-1, Doxiac, Doxibiot, Doxibiotic, Doxibrom, Doxicap, Doxiciclina, Doxicin, Doxiclat, Doxiclin, Doxicline, Doxiclival, Doxiclor, Doxicon, Doxicor, Doxicrisol, Doxigen, Doxil, Doxilina, Doximal, Doximar, Doximicina, Doximycin, Doxine, Doxinyl, Doxipan, Doxiplus, Doxirobe, Doxiryl, Doxitab, Doxiten bio, Doxitin, Doxivet, Doxivit, Doxlin, Doxoral, Doxsig, Doxy, Doxybene, Doxycap, Doxycat, Doxycin, Doxyclin, Doxycyclin, Doxycyclinum, Doxycyl, Doxydar, Doxyderm, Doxyderma, Doxydyn, Doxyfar, Doxyferm, Doxyhexal, Doxylag, Doxylan, Doxylets, Doxylin, Doxylis, Doxymax, Doxymed, Doxymina, Doxymix, ...
R05CB06 Ambroxol. R05CB07 Sobrerol. R05CB08 Domiodol. R05CB09 Letosteine. R05CB10 Combinations. R05CB11 Stepronin. R05CB13 ...
Ambroxol is a lysosomotropic drug of clinical use to treat conditions of productive cough for its mucolytic action. Ambroxol ... "A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca2+ release from acidic Ca2+ stores". Cell ... Presumably for this reason, Ambroxol was also found to improve cellular function in some disease of lysosomal origin such as ... "Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells". Brain. 137 (5): 1481- ...
Ambroxol has recently been shown to increase activity of the lysosomal enzyme glucocerebrosidase, so it may be a useful ... Ambroxol triggers the secretion of lysosomes from cells by inducing a pH-dependent calcium release from acidic calcium stores. ... "A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca2+ release from acidic Ca2+ stores". Cell ... "Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells". Brain. 137 (5): 1481- ...
LCT has supported trials in ambroxol, exenatide, simvastatin, liraglutide and others. A month later, in October, the Institute ...
Sometimes it is replaced by its metabolite ambroxol, as in Mucosolvan or Mucoangin. Broncholyte Elixir Bisolvon Paxirasol ...
2008). "Upregulation of AQP3 and AQP5 induced by dexamethasone and ambroxol in A549 cells". Respiratory physiology & ...
R05CB06 Ambroxol. R05CB07 Sobrerol. R05CB08 Domiodol. R05CB09 Letosteine. R05CB10 Combinations. R05CB11 Stepronin. R05CB12 ...
Cefuroxime and ambroxol". Arzneimittel-Forschung. 50 (8): 700-11. doi:10.1055/s-0031-1300276. PMID 10994153. ...
In contrast to Bay K8644, which is not for clinical use, Ambroxol is a frequently used mucolytic drug that triggers lysosomal ... "A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca2+ release from acidic Ca2+ stores". Cell ...
... ambroxol, salbutamol, phenylephrine, and dexamethasone. The marketing of the Claritin brand is important in the history of ...
... ambroxol, carbocisteine, erdosteine, mecysteine, and dornase alfa (some brand names are listed in the related articles). Adams ...
... ambroxol MeSH D02.092.146.290 --- benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide MeSH ... ambroxol MeSH D02.092.471.200 --- cystamine MeSH D02.092.471.245 --- dibenzylchlorethamine MeSH D02.092.471.302 --- ...
... ambroxol) Pharmaton (standardized ginseng extract, vitamins, minerals, trace elements) Silomat(dextromethorphan) Thomapyrin ( ...
... ambroxol (INN) ambruticin (INN) ambucaine (INN) ambucetamide (INN) ambuside (INN) Amcill amcinafal (INN) amcinafide (INN) ...
As of 2017, in a combination drug with ambroxol, it was available as Aliviatos, Ambroclar, Antitusivo L Labsa, Bronar, ... and in a combination drug with ambroxol and salbutamol as Sibilex.[25] ...
... is also anti-inflammatory, reducing redness in a sore throat. Ambroxol has recently been shown to increase activity of ... Ambroxol is often administered as an active ingredient in cough syrup. Ambroxol is indicated as "secretolytic therapy in ... Ambroxol also provides pain relief in acute sore throat. Pain in sore throat is the hallmark of acute pharyngitis. Sore throat ... Ambroxol is a potent inhibitor of the neuronal Na+ channels. This property led to the development of a lozenge containing 20 mg ...
Ipecac was used in cough mixtures as an expectorant or an emetic from the 18th until the early 20th century.[citation needed] For instance, Ipecac and opium were used to produce Dover's powder, which was used in syrup form.[citation needed] In 1965, the FDA approved the sale of up to one ounce of syrup of ipecac without a prescription. At the time it was approved, its use was recommended by the AAP, AAPCC, AMA, and the FDA's medical advisory board as a method to induce vomiting "for quick first-aid use in the home, under medical supervision", for use in cases of accidental poisoning.[2][3] Current guidelines from the American Academy of Pediatrics, however, strongly advise against this and in fact recommend the disposal of any syrup of ipecac present in the home.[4] Many toxicological associations have also issued position papers recommending against its use as a first-line treatment for most ingested poisons,[5] because of a lack of evidence that syrup of ipecac actually helps improve the ...
In the translation of messenger RNA molecules to produce polypeptides, cysteine is coded for by the UGU and UGC codons. Cysteine has traditionally been considered to be a hydrophilic amino acid, based largely on the chemical parallel between its sulfhydryl group and the hydroxyl groups in the side chains of other polar amino acids. However, the cysteine side chain has been shown to stabilize hydrophobic interactions in micelles to a greater degree than the side chain in the nonpolar amino acid glycine and the polar amino acid serine.[19] In a statistical analysis of the frequency with which amino acids appear in different chemical environments in the structures of proteins, free cysteine residues were found to associate with hydrophobic regions of proteins. Their hydrophobic tendency was equivalent to that of known nonpolar amino acids such as methionine and tyrosine (tyrosine is polar aromatic but also hydrophobic[20]), those of which were much greater than that of known polar amino acids such ...
Since mannitol is found in a wide variety of natural products, including almost all plants, it can be directly extracted from natural products, rather than chemical or biological syntheses. In fact, in China, isolation from seaweed is the most common form of mannitol production.[18] Mannitol concentrations of plant exudates can range from 20% in seaweeds to 90% in the plane tree. It is a constituent of saw palmetto (Serenoa).[25] Traditionally, mannitol is extracted by the Soxhlet extraction, using ethanol, water, and methanol to steam and then hydrolysis of the crude material. The mannitol is then recrystallized from the extract, generally resulting in yields of about 18% of the original natural product. Another method of extraction is using supercritical and subcritical fluids. These fluids are at such a stage that no difference exists between the liquid and gas stages, so are more diffusive than normal fluids. This is considered to make them much more effective mass transfer agents than ...
Reports of recreational use of glaucine have recently been published, and effects include dissociative-type symptoms; feeling detached and 'in another world', as well as nausea, vomiting and dilated pupils. These reports mirror those about the effects of clinical use, which state dissociative-type symptoms as well as lethargy, fatigue, hallucinations.[8][9] Investigation of side effects in a clinical setting also reports that the hallucinatory effects manifest as bright and colorful visualizations. They also report that patients perceive their environments clearly yet feel detached from it; "the patient sees and understands everything and is oriented well enough, but cannot take a clear and adequate action".[8]. One particular report of recreational use gone awry described the form of distribution as tablets being marketed as a 1-benzylpiperazine (BZP)-free "herbal high" which the patient referred to as "head candy".[9]. ...
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Examples are carbocisteine, ambroxol, and bromhexine.. *Expectorants are substances claimed to make coughing easier while ... ambroxol, and guaifenesin, sometimes with analgesics, antipyretics, anti inflammatories, and anticholinergics - and for ...
Ez a szócikk szaklektorálásra, tartalmi javításokra szorul. A felmerült kifogásokat a szócikk vitalapja részletezi. Ha nincs indoklás a vitalapon, bátran távolítsd el a sablont! ...
അഥവാ ഉള്ളടക്കം മറയ്ക്കാൻ നിർദേശിക്കുന്ന മറ്റേതെങ്കിലും പട്ടികകൾ ഉൾപ്പെടുത്തിയിട്ടുണ്ടെങ്കിൽ ഉള്ളടക്കം ...
Incluye indicaciones de AMBROXOL TEVAPHARMA y información detallade de Ambroxol hidrocloruro. ... oral 6 mg/ml,efectos secundarios, efectos adversos, precio (Ambroxol hidrocloruro) de TEVA PHARMA, B.V. es indicado para ... AMBROXOL RATIOPHARM EFG (RATIOPHARM ESPAÑA). AMBROXOL RATIOPHARM EFG Jarabe 3 mg/ml Composición:. Ambroxol hidrocloruro , 3.0 ... Ambroxol. Ambroxol pasa a la leche materna. Aunque no son de esperar efectos adversos en el lactante, no se recomienda su ...
... ambroxol + chlorpheniramine including usage, side effects, drug interaction, expert advice along with medicines associated with ... ambroxol + chlorpheniramine is used in the treatment of .get complete information about guaifenesin + ... Information about Guaifenesin + Ambroxol + Chlorpheniramine. Guaifenesin + ambroxol + chlorpheniramine uses. Common side ...
Ambroxol is also anti-inflammatory, reducing redness in a sore throat. Ambroxol has recently been shown to increase activity of ... Ambroxol is often administered as an active ingredient in cough syrup. Ambroxol is indicated as "secretolytic therapy in ... Ambroxol also provides pain relief in acute sore throat. Pain in sore throat is the hallmark of acute pharyngitis. Sore throat ... Ambroxol is a potent inhibitor of the neuronal Na+ channels. This property led to the development of a lozenge containing 20 mg ...
A list of US medications equivalent to Ambroxol Teva is available on the Drugs.com website. ... Ambroxol Teva is a medicine available in a number of countries worldwide. ... Ambroxol Teva may be available in the countries listed below.. Ingredient matches for Ambroxol Teva. Ambroxol. Ambroxol ...
A list of US medications equivalent to Ambroxol RUP Borisov is available on the Drugs.com website. ... Ambroxol RUP Borisov is a medicine available in a number of countries worldwide. ... Ingredient matches for Ambroxol RUP Borisov. Ambroxol. Ambroxol is reported as an ingredient of Ambroxol RUP Borisov in the ... Ambroxol RUP Borisov. Ambroxol RUP Borisov may be available in the countries listed below. ...
Find treatment reviews for ambroxol-amoxicillin from other patients. Learn from their experiences about effectiveness, side ...
Ambroxol hydrochloride is a medication indicated to alleviate chest congestion associated with conditions that include ... Ambroxol hydrochloride is not currently marketed in the United States but is used in other parts of the world. Patients should ... Treatment with ambroxol hydrochloride can lead to bowel movement changes in patients. This side effect can cause certain ... Rarely, patients taking ambroxol hydrochloride can experience an allergic reaction to this medication upon initial use. ...
Find the most comprehensive real-world treatment information on Ambroxol at PatientsLikeMe. 2 patients with fibromyalgia, ... bipolar I disorder or psoriasis currently take Ambroxol. ... Stopped taking Ambroxol Duration. Patients. This item is ... Why patients stopped taking Ambroxol. Multiple reasons could be selected. Reason. Patients. This item is relevant to you: ... What is Ambroxol?. Category: Prescription Drugs Most popular types: Frubizin Akut Mucoangin Mucopect Mucosal Mucosolvan Retard ...
The recently published report titled United States Ambroxol Industry 2017 Market Research Report is an in depth study providing ... United States Ambroxol Market 2018 1 Ambroxol Overview. 1.1 Product Overview and Scope of Ambroxol. 1.2 Classification of ... 4.2 United States Ambroxol Revenue and Market Share by Type (2012-2017). 4.3 United States Ambroxol Price by Type (2012-2017). ... 6.1.2 Ambroxol Product Category, Application and Specification. 6.1.2.1 Product A. 6.1.2.2 Product B. 6.1.3 Teva Ambroxol Sales ...
Find out how to take Ambroxol (drug) and its dose. Describes the best time to take the drug and precautions if any that should ... How to Take Ambroxol and Dose of Ambroxol Written & Compiled by Madhumathi Palaniappan , Medically Reviewed by The Medindia ... Ambroxol - Information. Ambroxol is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with ... Find out how to take Ambroxol (drug) and its dose. Describes the best time to take the drug and precautions if any that should ...
... ambroxol hydrochloride manufacturers, ambroxol hydrochloride suppliers, ambroxol hcl exporters and manufacturing companies from ... Here you will find listings of ambroxol hcl, ... Ambroxol is a mucolytic agent which reduces the thickness of ... Ambroxol Hydrochloride Syrup Erlotinib Hydrochloride Thiamine Hydrochloride Glucosamine Hydrochloride L Cysteine Hydrochloride ... Ambroxol Hydrochloride is a clinically proven systemically active mucolytic agent. When administered orally onset of action ...
Effect of ambroxol on blood and CSF biomarkers [ Time Frame: Day 1-186 ]. Quantify the effects of ambroxol on biomarkers of ... Glucocerebrosidase and ambroxol levels in blood and cerebrospinal fluid [ Time Frame: Day 1-186 ]. Assess ambroxols central ... Ambroxol in Disease Modification in Parkinson Disease (AiM-PD). The safety and scientific validity of this study is the ... Tolerability and Pharmacodynamic Effects of Ambroxol in Patients With Parkinson Disease: Ambroxol in Disease Modification in ...
Tussefar information about active ingredients, pharmaceutical forms and doses by Faran Laboratories, Tussefar indications, usages and related health products lists
Puntol information about active ingredients, pharmaceutical forms and doses by Velka Hellas, Puntol indications, usages and related health products lists
A k sz tm ny ambroxol (br mhexin-sz rmaz k) tartalm , ny ko ... Milyen t pus gy gyszer az Ambroxol-TEVA tabletta s milyen ... 1. Milyen t pus gy gyszer az Ambroxol-TEVA tabletta s milyen betegs gek eset n alkalmazhat ?. A k sz tm ny ambroxol (br mhexin- ... 2. Tudnival k az Ambroxol-TEVA tabletta szed se el tt. Ne szedje az Ambroxol-TEVA tablett t. - ha allergi s az ambroxolra, ... Az Ambroxol-TEVA tabletta egy ttad sa ker lend a k h g si reflexet g tl k h g scsillap t kkal, mert azok az ambroxol ltal ...
Ambroxol(Aeroflux) generic is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis ... Ambroxol +Pharma, Ambroxol Abz, Ambroxol Acis, Ambroxol Al Comp, Ambroxol Al, Ambroxol Aphar, Ambroxol Aristo, Ambroxol Arrow, ... Ambroxol Cinfa, Ambroxol Domesco, Ambroxol Genfar, Ambroxol Germed, Ambroxol Jaba, Ambroxol Jarabe, Ambroxol LCh, Ambroxol La ... Ambroxol Stada, Ambroxol Temmler, Ambroxol Teva Conseil, Ambroxol Vramed, Ambroxol, Ambroxol-1a Pharma, Ambroxol-Ct, Ambroxol- ...
Ambroxol. Drug Summary. 2015 Full text (in our servers) *DGF. Dirección General de Farmacia. Servicio Canario de la Salud. ... Ambroxol. Ficha técnica. 2016 Full text (in our servers) *MRI-CTS. ... Celltius™. Contains other elements than Ambroxol in its composition *Coricidin Expec (Mexico)™. Contains other elements than ... The pharmacokinetics and bioequivalence of various dosage forms of ambroxol]. Arzneimittelforschung. 1985;35(10):1591-5. German ...
... ambroxol inn:ban, ambroxol ep impurity d, ambroxol base, ambroxolum inn-latin, rac-cis-ambroxol. ... ambroxol inn:ban, ambroxol ep impurity d, ambroxol base, ambroxolum inn-latin, rac-cis-ambroxol. ... ambroxol inn:ban, ambroxol ep impurity d, ambroxol base, ambroxolum inn-latin, rac-cis-ambroxol. ... Preclinically, ambroxol, the active ingredient of Mucosolvan, has been shown to increase respiratory tract secretion. It ...
We evaluated the add-on effect of ambroxol to the treatment of fibromyalgia. We studied 25 patients with fibromyalgia. Ambroxol ... Ambroxol is a secretolytic agent used in the treatment of various airway disorders. Recently, it was discovered that this ... Chenot JF, Weber P, Friede T (2014) Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis. BMC Fam Pract 15:45. doi: ... In this pilot study, the use of ambroxol was associated to decreased fibromyalgia pain and improved fibromyalgia symptoms. The ...
Ambroxol secretolytic drug molecule. Also often used in treatment of soar throat. Atoms are represented as spheres with ... Caption: Ambroxol secretolytic drug molecule. Also often used in treatment of soar throat. Atoms are represented as spheres ... Keywords: 3 dimensional, 3d, ambroxol, ambroxole, anaesthetic, antitussive, artwork, atomic structure, atoms, biological, ...
The Investigation Report on Chinas Ambroxol Market, 2018-2022 report has been added to ResearchAndMarkets.coms offering. ... The chemical constituent of Ambroxol is ambroxol hydrochloride, an active metabolite of Bromhexine. In 1981, Ambroxol (trade ... Ambroxol is sold in China in the dosage forms of injections, solutions, syrups, granules, tablets and capsules. Injections ... After years of development, third-generation expectorant Ambroxol has become the most common drug in the clinical treatment of ...
Efficacy and Safety Study of New Ambroxol Hardboiled Lozenges in Acute Pharyngitis (DELICIOUS). The safety and scientific ... To assess the efficacy of the new hard boiled Ambroxol lozenges 20 mg for the relief of sore throat pain in patients with acute ... Active Comparator: Ambroxol hydrochloride (BIH1526) One lozenge 20 mg on as-needed basis, up to 6 times per day ... To assess the safety of the new hard boiled Ambroxol lozenges 20 mg in patients with acute pharyngitis. ...
Market Research Report 2018 aims at providing comprehensive data on ambroxol hydrochloride market globally and ... Ambroxol hydrochloride prices in other regions. 7. AMBROXOL HYDROCHLORIDE END-USE SECTOR 7.1. Ambroxol hydrochloride market by ... Ambroxol hydrochloride market forecast. 6. AMBROXOL HYDROCHLORIDE MARKET PRICES. 6.1. Ambroxol hydrochloride prices in Europe. ... Ambroxol hydrochloride application spheres, downstream products. 3. AMBROXOL HYDROCHLORIDE MANUFACTURING METHODS. 4. AMBROXOL ...
Experimental: Ambroxol Ambroxol therapy will be dosed up to 600 mg/day divided to twice a day starting 150 mg for the first ... Drug: Ambroxol Ambroxol Hydrochloride therapy will be dosed up to 600 mg/day divided to twice a day starting 150 mg for the ... In addition to a mucolytic action, ambroxol has antioxidant and anti-inflammatory properties. Importantly, ambroxol therapy was ... Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy. The safety and ...
of Ambroxol Hydrochloride and Cetirizine Hydrochloride in pH 6.8 phosphate buffer. Both of these drugs obeyed Beer-Lamberts ... Ambroxol Hydrochloride and Cetirizine Hydrochloride are used for the treatment of bronchitis, cough, and allergy. A simple, ... Simultaneous Estimation of Ambroxol Hydrochloride and Cetirizine Hydrochloride in Pharmaceutical Tablet Dosage Form by ... Hence, the proposed method can be employed for quantitative estimation of Ambroxol Hydrochloride and Cetirizine Hydrochloride ...
  • SUBSTANCE: present invention refers to application of antiinflammatory and local anaesthetic pharmaceutical compositions containing ambroxol or one of its pharmacologically acceptable salts for local application for skin diseases chosen from the group including anaesthesia, burning, itching, inflammation, mosquito stings and skin redness of allergic, immunologic or idiopathic origin, applied directly on the skin. (russianpatents.com)
  • The present invention relates to possess anti-inflammatory and mestnoanesteziruushim properties, pharmaceutical compositions containing Ambroxol or one of its pharmacologically acceptable salts, preferably Ambroxol in the form of its hydrochloride, and intended for local use by direct application or applying to the skin and/or mucous membrane. (russianpatents.com)
  • With the invention it has been unexpectedly found that pharmaceutical compositions for topical application containing Ambroxol or one of its pharmacologically acceptable salts and intended for direct application or applying to the skin and/or mucous membranes, anti-inflammatory and mestnoanesteziruushim properties. (russianpatents.com)
  • Preferred pharmaceutical compositions for topical application containing Ambroxol in the form of its hydrochloride. (russianpatents.com)
  • Especially preferred pharmaceutical compositions for topical application in the form of a dosage form selected from the group including gels, hydrophilic paste, mash and solutions containing Ambroxol from 0.1 to 20 wt. (russianpatents.com)
  • In another preferred embodiment, the invention provides pharmaceutical compositions for topical application in the form mucoadhesive patches containing Ambroxol from 1 to 50 wt. (russianpatents.com)
  • Apart from Dextromethorphan Cetirizine Phenylephrine Ambroxol Tablets Manufacturers Suppliers, we at Trumac Healthcare provide range of other products across several divisions. (trumachealthcare.net)
  • However, with therapeutic effect of a composition containing Ambroxol or its salt as the act is its substance and intended for local use by direct application to the skin, accordingly, the mucous membrane and to treat them in the level technique is not described. (russianpatents.com)
  • Exceptional Toxicological profile of Ambroxol also allows the use of such containing compositions on large areas of skin and/or mucous membranes, as well as to increase the duration of their application. (russianpatents.com)
  • De asemenea, AMBROXOL EGIS comprimate este indicat pre- si postoperator. (egis.ro)
  • Acordati atentie utilizarii AMBROXOL EGIS comprimate In cazul in care suferiti de ulcer gastroduodenal. (egis.ro)
  • Deoarece, foarte rar, au fost descrise cefalee si vertij in timpul tratamentului cu AMBROXOL EGIS comprimate, se recomanda prudenta la pacientii care conduc vehicule sau folosesc utilaje. (egis.ro)
  • Datorita continutului in lactoza al AMBROXOL EGIS comprimate pacientii cu afectiuni ereditare de intoleranta la galactoza, deficit de lactaza (Lapp), sau sindrom de malabsorbtie la glucoza-galactoza nu trebuie sa utilizeze acest medicament. (egis.ro)
  • Administrarea concomitenta de AMBROXOL EGIS comprimate si antibiotice (amoxicilina, cefuroxima, eritromicina, doxiciclina) duce la cresterea concentratiei de antibiotice la nivelul pulmonar. (egis.ro)
  • AMBROXOL EGIS comprimate nu se administreaza concomitent cu antitusive si/sau cu substante care scad secretia bronsica (de exemplu, de tip atropinic), aceste asocieri fiind nejustificate. (egis.ro)
  • Daca aveti impresia ca efectul AMBROXOL EGIS comprimate este prea puternic sau prea slab intrebati medicul dumneavoastra sau farmacistul. (egis.ro)
  • Daca ati utilizat mai mult AMBROXOL EGIS comprimate decat trebuie, anuntati imediat medicul dumneavoastra sau farmacistul. (egis.ro)
  • AMBROXOL EGIS comprimate este in general bine tolerat dar, ca toate medicamentele poate determina reactii adverse. (egis.ro)
  • Ambroxol+Cetirizine+Dextromethorphan Hydrobromide+Phenylephrine is used in the treatment of dry cough . (trumachealthcare.net)
  • Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome. (thedojo.mobi)
  • Lazzarin, A, Luerti, M & Uberti-Foppa, C 1984, ' Polymorphonuclear leucocytes functions from premature infants after prevention of respiratory distress syndrome with betamethasone and ambroxol ', Biological Research in Pregnancy and Perinatology , vol. 5, no. 3, pp. 130-134. (elsevier.com)
  • Ambroxol also provides pain relief in acute sore throat. (wikipedia.org)
  • The main property of Ambroxol for treating sore throat is the local anaesthetic effect, described first in the late 1970s, but explained and confirmed in more recent work. (wikipedia.org)
  • Many state-of-the-art clinical studies have demonstrated the efficacy of Ambroxol in relieving pain in acute sore throat, with a rapid onset of action, with its effect lasting at least three hours. (wikipedia.org)
  • Ambroxol is also anti-inflammatory, reducing redness in a sore throat. (wikipedia.org)
  • To assess the efficacy of the new hard boiled Ambroxol lozenges 20 mg for the relief of sore throat pain in patients with acute pharyngitis. (clinicaltrials.gov)
  • In WO 00/38653 described improved dosage form intended for transdermal administration of corticosteroids, and along with many other antioxidants also mentioned Ambroxol as excipients, suitable for protection against oxidative decomposition. (russianpatents.com)
  • Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. (wikipedia.org)
  • In these samples the Investigators will measure ambroxol drug levels, assess whether the glucocerebrosidase enzyme has been stimulated and the levels of other substances thought to be associated with the development of PD and confirm whether the study drug has penetrated the cerebrospinal fluid and CNS. (clinicaltrials.gov)
  • If the study proves ambroxol penetrates the CNS and replicates our current findings in the laboratory, the Investigators shall move on to a much larger drug trial to test whether the study drug may be able to slow the progression of PD. (clinicaltrials.gov)
  • Thus, ambroxol, an oral available drug on the market, may be a safe option for GD patients with potential disease-specific efficacy and should be expanded into a clinical trial using higher doses and placebo-controlled design. (clinicaltrials.gov)
  • Ambroxol (Ax) is a frequently prescribed drug used to facilitate mucociliary clearance, but its mode of action is yet poorly understood. (salford.ac.uk)
  • Patients should discuss the limited ambroxol hydrochloride side effects with a doctor before beginning treatment. (livestrong.com)
  • To limit the development of these side effects, ambroxol hydrochloride should be taken with food. (livestrong.com)
  • Gastrointestinal reactions are the common side effects linked to Ambroxol. (knoji.com)
  • If any of these Ambroxol side effects become pertinent or bothersome, seek for immediate medical help. (knoji.com)
  • Dry mouth, problem in urination, headache, weakness and continuous running nose are rare Ambroxol side effects reported in patients. (knoji.com)
  • In case any of these side effects occur, stop using Ambroxol, and consult a doctor immediately. (knoji.com)
  • These are not the complete list of possible Ambroxol side effects, for further information, consult your doctor. (knoji.com)
  • Ambroxol may interact and cause severe side effects, if administered in combination with other drugs. (knoji.com)