In vitro activities of two antimitotic compounds, pancratistatin and 7-deoxynarciclasine, against Encephalitozoon intestinalis, a microsporidium causing infections in humans. (1/54)

The antiparasitic effect of a collection of compounds with antimitotic activity has been tested on a mammalian cell line infected with Encephalitozoon intestinalis, a microsporidian causing intestinal and systemic infection in immunocompromised patients. The antiparasitic effect was evaluated by counting the number of parasitophorous vacuoles detected by immunofluorescence. Out of 526 compounds tested, 2 (pancratistatin and 7-deoxynarciclasine) inhibited the infection without affecting the host cell. The 50% inhibitory concentrations (IC(50)s) of pancratistatin and 7-deoxynarciclasine for E. intestinalis were 0.18 microM and 0.2 microM, respectively, approximately eightfold lower than the IC(50)s of these same compounds against the host cells. Electron microscopy confirmed the gradual decrease in the number of parasitophorous vacuoles and showed that of the two life cycle phases, sporogony was more sensitive to the inhibitors than merogony. Furthermore, the persistence of meronts in some cells apparently devoid of sporonts and spores indicated that the inhibitors block development rather than entry of the parasite into the host cell. The occurrence of binucleate sporoblasts and spores suggests that these inhibitors blocked a specific phase of cell division.  (+info)

Lycobetaine acts as a selective topoisomerase II beta poison and inhibits the growth of human tumour cells. (2/54)

The phenanthridine alkaloid lycobetaine is a minor constituent of Amaryllidaceae. Inhibition of cell growth was studied in the clonogenic assay on 21 human tumour xenografts (mean IC(50) = 0.8 microM). The growth of human leukaemia cell lines was also potently inhibited (mean IC(50) = 1.3 microM). Athymic nude mice, carrying s.c. implanted human gastric tumour xenograft GXF251, were treated i.p. with lycobetaine for 4 weeks, resulting in a marked tumour growth delay. Lycobetaine was found to act as a specific topoisomerase II beta poison. In the presence of calf thymus DNA, pure recombinant human topoisomerase II beta protein was selectively depleted from SDS-gels, whereas no depletion of topoisomerase II alpha protein was observed. In A431 cells immunoband-depletion of topoisomerase II beta was induced, suggesting stabilization of the covalent catalytic DNA-intermediate in living cells. It is reasonable to assume that this mechanism will cause or at least contribute significantly to the antitumour activity.  (+info)

Inhibition of cell cycle progression through specific phase by pancratistatin derivatives. (3/54)

Pancratistatin derivatives, 1-O-(3-hydroxybutyryl)pancratistatin (HBP) and 1-O-(3-O-beta-D-glucopyranosylbutyryl)pancratistatin (GBP), showed strong cytostatic activity against rat embryo fibroblast 3Y1 at concentrations less than 1 microM. When the effect on cell cycle progression was examined in 3Y1 fibroblasts arrested at G0/G1 phase by serum deprivation, HBP, GBP, and pancratistatin inhibited the progression of 3Y1 fibroblasts from G0/G1 to S phase. In addition, when the effect on cell cycle progression was studied in 3Y1 fibroblasts synchronized at late G1/early S phases by treating with hydroxyurea, HBP blocked further progression through S phase, while GBP and pancratistatin did not affect the progression, but retarded it. On the other hand, when the effect of HBP and GBP on the progression was evaluated in promyelocytic leukemia HL-60RG cells synchronized at G0/G1 phase, the cells did not progress into S phase and accumulated in sub G0/G1 phase, which indicated apoptotic cells. These findings suggest that of Amaryllidaceae alkaloids, HBP blocks the progression of cell cycle at least at G0/G1 and S phases and GBP does at least at G0/G1 phase, resulting in apoptosis induction in tumor cells.  (+info)

Isolation of the acetylcholinesterase inhibitor ungeremine from Nerine bowdenii by preparative HPLC coupled on-line to a flow assay system. (4/54)

In an attempt to isolate the active compound while detecting acetylcholinesterase inhibitory activity, we applied a fluorometric flow assay system to an on-line coupled preparative HPLC. The MeOH extract of Nerine bowdenii showed a strong inhibitory peak in the on-line assay, and the active compound was isolated by CPC and HPLC. It was identified as ungeremine by analysis of its (1)H-NMR, 2D-NMR, and NOESY spectra. The assignment of the active N. bowdenii constituent was also confirmed by co-TLC, co-HPLC, and co-(1)H-NMR experiments using an authentic sample of synthetic ungeremine. The IC(50) value of ungeremine was 0.35 microM, showing stronger activity than galanthamine (2.2 microM).  (+info)

Localization of ascorbic acid, ascorbic acid oxidase, and glutathione in roots of Cucurbita maxima L. (5/54)

To understand the function of ascorbic acid (ASC) in root development, the distribution of ASC, ASC oxidase, and glutathione (GSH) were investigated in cells and tissues of the root apex of Cucubita maxima. ASC was regularly distributed in the cytosol of almost all root cells, with the exception of quiescent centre (QC) cells. ASC also occurred at the surface of the nuclear membrane and correspondingly in the nucleoli. No ASC could be observed in vacuoles. ASC oxidase was detected by immunolocalization mainly in cell walls and vacuoles. This enzyme was particularly abundant in the QC and in differentiating vascular tissues and was absent in lateral root primordia. Administration of the ASC precursor L-galactono-gamma-lactone markedly increased ASC content in all root cells, including the QC. Root treatment with the ASC oxidized product, dehydroascorbic acid (DHA), also increased ASC content, but caused ASC accumulation only in peripheral tissues, where DHA was apparently reduced at the expense of GSH. The different pattern of distribution of ASC in different tissues and cell compartments reflects its possible role in cell metabolism and root morphogenesis.  (+info)

Effects of lycorine on HL-60 cells via arresting cell cycle and inducing apoptosis. (6/54)

As a natural anti-cancer alkaloid extracted from Amaryllidaceae, lycorine shows various biological effects on tumor cells. The survival rate of HL-60 cells exposed to lycorine was decreased in a dose-dependent manner with 1 microM as the 50% inhibitory concentration (IC50), cell growth was slowed down by arresting cell cycle at G2/M phase, and cell regeneration potential was inhibited. HL-60 cells exhibited typical apoptotic morphological changes, apoptotic DNA "ladder" pattern, and sub-G1 peak in cell phase distribution, showing apoptosis of HL-60 cells. To further understand the apoptotic molecular mechanism of lycorine on HL-60 cells, caspase activity was tested by colorimetric assay, and the expression of Bcl-2 and Bax proteins was examined by Western blotting. The increase of caspase-8, -9, -3 activities demonstrated that caspase was a key mediator of apoptotic pathways induced by lycorine. Under-expression of Bcl-2 and increase of Bax:Bcl-2 ratio showed that Bcl-2 family proteins were involved in apoptosis. Our finding suggests that lycorine can suppress leukemia growth and reduce cell survival via arresting cell cycle and inducing apoptosis of tumor cells.  (+info)

Antineoplastic agents. 553. The Texas grasshopper Brachystola magna. (7/54)

Bioassay (P388 lymphocytic leukemia cell line and human cancer cell lines) guided separation of an extract prepared from the previously chemically uninvestigated Texas grasshopper Brachystola magna led to isolation of the cancer cell growth inhibitory pancratistatin (1), narciclasine (2), and ungeremine (3). Pancratistatin (1) was first isolated from the bulbs of Hymenocallis littoralis), and the original crystal structure was deduced by X-ray analysis of a monomethyl ether derivative. In the present study pancratistatin (1) was isolated from an extract of B. magna, which led to the X-ray crystal structure of this anticancer drug. Since isoquinoline derivatives 1-3 are previously known only as constituents of amaryllidaceous plants, some of the interesting implications of their rediscovery in the grasshopper B. magna that does not appear to utilize amaryllis family plants were discussed.  (+info)

An efficient synthesis of (+/-)-Lycoricidine featuring a Stille-IMDAF cycloaddition cascade. (8/54)

[reaction: see text] A highly efficient total synthesis of (+/-)-Lycoricidine is described. The synthesis features the ready preparation of the Lycoricidine skeleton by a Stille-IMDAF cycloaddition cascade. The resulting cycloadduct is then used for the stereocontrolled installation of the other functionality present in the C-ring of the target molecule.  (+info)

*4-Methylcatechol

The Amaryllidaceae Alkaloids. In.: Arnold Brossi (ed.) The Alkaloids, Chapter 3. Academic Press.. ... Members of the monocot subfamily Amaryllidoideae present a unique type of alkaloids, the norbelladine alkaloids, which are 4- ...

*Scadoxus puniceus

Koorbanally, N. A.; Raghoo, M. & Crouch, N. R. (2006). "Amaryllidaceae alkaloids from Scadoxus puniceus" (PDF). The American ... The alkaloids in the plant include haemanthamines, haemanthidine, 6-β-hydroxycrinamine, scapunine, and scadoxucines. ...

*Homolycorine

... is one of a number of toxic alkaloids found in various Amaryllidaceae species such as daffodils (Narcissus). Four ... "CHEMICAL AND BIOLOGICAL ASPECTS OF Narcissus ALKALOIDS", in "The Alkaloids: Chemistry and Biology" (G. A. Cordell, ed.), Vol. ... new Amaryllidaceae alkaloids from Zephyranthes candida. Shitara N, Hirasawa Y, Hasumi S, Sasaki T, Matsumoto M, Wong CP, Kaneda ...

*Hamayne

... is an alkaloid present in plants of the family Amaryllidaceae, including Iberian Narcissus species and two Nigerian ... "Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts". Life Sciences. 71 (21): 2521 ... "The Total Synthesis of the Crinine Alkaloid Hamayne via a Pd[0]-Catalyzed Intramolecular Alder-Ene Reaction". Organic Letters. ...

*Aza-Cope rearrangement

Crinine is an alkaloid of the Amaryllidaceae family, and its asymmetric total synthesis was one of the first using the aza-Cope ... Total synthesis of Amaryllidaceae alkaloids of the 5,11-methanomorphanthridine type. Efficient total syntheses of (−)- ... Stereoselective preparation of cis-3a-aryloctahydroindoles and a new short route to Amaryllidaceae alkaloids". J. Am. Chem. Soc ... A short synthesis of the amaryllidaceae alkaloid d,1-crinine". Tetrahedron Lett. 67 (51): 2741-2744. doi:10.1016/S0040-4039(00) ...

*Galantamine total synthesis

"Approaches to the Biogenetic-type Asymmetric Synthesis of Some Amaryllidaceae Alkaloids". Heterocycles. 6 (9): 1752. doi: ... "A Biogenetic-type Asymmetric Synthesis of Optically Active Amaryllidaceae Alkaloids: (+)- and (−)-Galanthamine from L-Tyrosine ... 3-diones and Total Synthesis of Diverse Families of Sterically Congested Alkaloids". The Journal of Organic Chemistry. 73 (19 ...

*Pancratistatin

Nair JJ, Bastida J, Codina C, Viladomat F, van Staden J (September 2013). "Alkaloids of the South African Amaryllidaceae: a ... Amaryllidaceae isocarbostyril alkaloids and their derivatives as promising antitumor agents. Transl Oncol 2008, 1, 1-13. ... "Cytotoxic agents of the crinane series of amaryllidaceae alkaloids". Nat Prod Commun (Review). 7 (12): 1677-88. PMID 23413581. ... Synthesis of Amaryllidaceae Constituents and Unnatural Derivatives M. Ghavre, J. Froese, M. Pour, T. Hudlicky, Angew. Chem. Int ...

*Zephyranthes rosea

"Analysis of Amaryllidaceae alkaloids from Zephyranthes grandiflora by GC/MS and their cholinesterase activity" (PDF). Brazilian ... S. L. (Amaryllidaceae, Hippeastreae), with Notes on the Genus in Colombia" (PDF). Rev. Acad. Colomb. Cienc. 28 (107): 177-186. ... The bulbs of Z. rosea, like other members of Zephyranthes and Habranthus, contain various toxic alkaloids including lycorine ... "Hippeastreae". Amaryllidaceae.org. Retrieved August 9, 2011. "Zephyranthes rosea Lindl". Germplasm Resources Information ...

*Habranthus robustus

Lucie Cahlíková; Irena Valterová; Kateřina Macáková; Lubomír Opletal (2010). "Analysis of Amaryllidaceae alkaloids from ... S. L. (Amaryllidaceae, Hippeastreae), with Notes on the Genus in Colombia" (PDF). Rev. Acad. Colomb. Cienc. 28 (107): 177-186. ... Mainly galanthamine-type alkaloids which can be lethal for humans. "Habranthus robustus Herb". Germplasm Resources Information ... It is classified under the subfamily Amaryllidoideae of the Amaryllis family (Amaryllidaceae). In broader classifications, they ...

*Zephyranthes carinata

Lucie Cahlíková; Irena Valterová; Kateřina Macáková & Lubomír Opletal (2010). "Analysis of Amaryllidaceae alkaloids from ... S. L. (Amaryllidaceae, Hippeastreae), with Notes on the Genus in Colombia" (PDF). Rev. Acad. Colomb. Cienc. 28 (107): 177-186. ... Ji Zhanhe & Alan W. Meerow (2000). "Amaryllidaceae" (PDF). Flora of China (中国植物志). Science Press & the Missouri Botanical ... It is classified under the subfamily Amaryllidoideae of the Amaryllis family (Amaryllidaceae). In broader classifications, they ...

*Hippeastrum

Takos, Adam; Rook, Fred (31 May 2013). "Towards a Molecular Understanding of the Biosynthesis of Amaryllidaceae Alkaloids in ... Vigneron, Pascal (2008). "Amaryllidaceae". Amaryllidaceae.org (in French). Retrieved 2 April 2014. Vigneron, Pascal. " ... and psychopharmacological activity due to their high alkaloid content. One alkaloid isolated from Hippeastrum vittatum ( ... Herbert, William (1837). Amaryllidaceae: Preceded by an Attempt to Arrange the Monocotyledonous Orders, and Followed by a ...

*Lycorine

... is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (Clivia ... Lycorine is the most frequent alkaloid of Amaryllidaceae. Lycorine inhibits protein synthesis, and may inhibit ascorbic acid ... was most likely in North Africa and the Iberian peninsula and that lycorine is one of the oldest in the Amaryllidaceae alkaloid ... Lycorine is found in different species of Amaryllidaceae which include flowers and bulbs of daffodil, snowdrop (Galanthus) or ...

*Galantheae

... approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe ... "Amaryllidaceae". Amaryllidaceae.org (in French). Retrieved 23 October 2014. Stevens, P.F. (2001-2012), Angiosperm Phylogeny ... 1998 Amaryllidaceae. In K. Kubitzki [ed.], Families and genera of vascular plants, vol. 3, 83-110. Springer-Verlag, Berlin.* ... 1999 Systematics of Amaryllidaceae based on cladistic analysis of plastid sequence data. American Journal of Botany. 86: 1325. ...

*Narciclasine

... is a toxic alkaloid found in various Amaryllidaceae species. Kornienko A, Evidente A (2008). "Chemistry, biology, ... "Narciclasine as well as other Amaryllidaceae Isocarbostyrils are Promising GTP-ase Targeting Agents against Brain Cancers". ...

*Nina Rønsted

... approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe ... 2012). "Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae". ... Snowdrops falling slowly into place: An improved phylogeny for Galanthus (Amaryllidaceae). Molecular Phylogenetics and ...

*Narcissus asturiensis

Lewis, John R. (2000). "Amaryllidaceae, muscarine, imidazole, oxazole, thiazole and peptide alkaloids, and other miscellaneous ... This plant contains a number of alkaloids including hemanthamine, hemanthidine, tazettine and epimacronine. Santos, A.; Fidalgo ... a threatened species of the Amaryllidaceae". Journal of horticultural science & biotechnology. 77 (2): 149-152. ... alkaloids" (PDF). Nat. Prod. Rep. 17 (1): 57-84. doi:10.1039/a809403i. PMID 10714899. ...

*Brunsvigia bosmaniae

"Alkaloids of the amaryllidaceae: Brunsvigine" - Tetrahedron, Volume 31, Issue 16, Pages 1855-1859 - R.C. Clark, F.L. Warren, K. ... Brunsvigia bosmaniae is a gregarious South African geophyte belonging to the family Amaryllidaceae, and occurring along the dry ... Brunsvigia species are rich in alkaloids, particularly brunsvigine or 5,11b-methanomorphanthridine, and may be extremely toxic ...

*Alkaloid

260-263 Plemenkov, p. 242 Begley, Cofactor Biosynthesis John R. Lewis (2000). "Amaryllidaceae, muscarine, imidazole, oxazole, ... of those contain alkaloids. Therefore, in the past the term "alkaloid" was associated with plants. The alkaloids content in ... attributed to isoquinoline alkaloids. Main classes of monomeric alkaloids are listed in the table below: Most alkaloids contain ... Most alkaloids are present in the raw plants in the form of salts of organic acids. The extracted alkaloids may remain salts or ...

*Boophone

A variety of alkaloids with affinity for the serotonin transporter have been isolated from Boophone alkaloids. Appendix: 18 ( ... Boophone is a genus of herbaceous, perennial and bulbous plants in the Amaryllis family (Amaryllidaceae, subfamily ... Sandager M, Nielsen ND, Stafford GI, van Staden J, Jäger AK (2005). "Alkaloids from Boophane disticha with affinity to the ... Neergaard J, Andersen J, Pedersen ME, Stafford GI, van Staden J, Jäger AK (2009). "Alkaloids from Boophone disticha with ...

*Hymenocallis pimana

They say that the bulbs were boiled in lye to remove toxic alkaloids before consumption. This is the only known instance of any ... is a member of the genus Hymenocallis, in the family Amaryllidaceae. Common name in English is Pima spider-lily; in Spanish it ... Hymenocallis pimana (Amaryllidaceae): a new species from northwestern Mexico. Phytologia 68(4):255-259. Laferrière, Joseph E., ... Native detoxification of bulbs of Mountain Pima spider-lily (Hymenocallis pimana, Amaryllidaceae). Economic Botany 52(2):207- ...

*Families of Asparagales

The amaryllis subfamily of the Amaryllidaceae sensu lato is treated in some systems as a separate family, the Amaryllidaceae ... the presence of saponins and the absence of the alkaloids typical of amaryllids. Agapanthus is widely grown as an ornamental in ... Amaryllidaceae and Agapanthaceae (e.g. in the APG II system). 'Amaryllidaceae' is used as a conserved name in APG III. The name ... The allium subfamily of the Amaryllidaceae sensu lato is treated in some systems as a separate family, the Alliaceae. Members ...

*Galantamine

It is an alkaloid that has been isolated from the bulbs and flowers of Galanthus caucasicus (Caucasian snowdrop), Galanthus ... woronowii (Voronov's snowdrop), and some other members of the family Amaryllidaceae, such as Narcissus (daffodil), Leucojum ... Mashkovsky, MD; Kruglikova-Lvova, RP (1951). "On the pharmacology of the new alkaloid galantamine". Farmakologia Toxicologia. ...

*Ismene amancaes

Willaman, John James; Schubert, Bernice (1961). Alkaloid-bearing Plants and Their Contained Alkaloids. U.S. Department of ... Ismene amancaes, commonly called amancae or amancay, is a herbaceous plant species in the Amaryllidaceae family and native to ... It is reported that I. amancaes contains the alkaloid substances galantamine and narcissidine. Remains of I. amancaes have been ... Glasby, John (2012). Encyclopedia of the Alkaloids: Volume 2 (I-Z). Springer Science & Business Media. p. 988. ISBN ...

*Iris iberica subsp. elegantissima

John James Willaman and Bernice Schubert Alkaloid-bearing Plants and Their Contained Alkaloids (August 1961), p. 94, at Google ... Dönmez, Emel Oybak; Işik, Serap (2008). "Pollen morphology of Turkish Amaryllidaceae, Ixioliriaceae and Iridaceae" (PDF). Grana ... It has a chromosome count: 2n=20, and has an unnamed alkaloid (as of 1961), contained within its rhizome. A study in 2014, was ...

*Clivia

They are from the family Amaryllidaceae, subfamily Amaryllidoideae. Common names are Natal lily or bush lily. They are ... Some species of Clivia, including Clivia miniata (sometimes called the kaffir lily), produce small amounts of the alkaloid ... Conrad, Ferozah (February 2008). Molecular Systematics, Biogeography and Dating of the tribe Haemantheae (Amaryllidaceae) and ... "Generic relationships among the baccate-fruited Amaryllidaceae (tribe Haemantheae) inferred from plastid and nuclear non-coding ...

*Narcissus pseudonarcissus

Like all Narcissus species, daffodils contain the alkaloid poison lycorine, mostly in the bulb, but also in the leaves. Because ... Amaryllidaceae)". Botanical Journal of the Linnean Society. 177 (2): 246-262. doi:10.1111/boj.12240. Media related to Narcissus ...
Detail záznamu - Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity - Detail záznamu - Knihovna Akademie věd České republiky
TY - JOUR. T1 - Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors. AU - Cortes, Natalie. AU - Sierra, Karina. AU - Tallini, Luciana. AU - Borges, Warley de S.. AU - de Andrade, Jean Paulo. AU - Bastida, Jaume. AU - Osorio, Edison. PY - 2019/8/12. Y1 - 2019/8/12. U2 - 10.3390/proceedings2019022066. DO - 10.3390/proceedings2019022066. M3 - Artículo. VL - 22. JO - Proceedings. JF - Proceedings. SN - 2504-3900. IS - 66. ER - ...
Except where otherwise noted, content on this site is licensed under a Creative Commons Attribution, Non-Commercial, Share Alike CC BY-NC-SA Licence.. ...
Pancratistatin has been selected for pre-clinical development but is sparingly soluble in water. A disodium phosphate derivative has been synthesized which is water soluble and is bioequivalent thereof. The critical step in the synthesis of the phenolic phosphate was phosphorylation of 1,2,3,4-tetraacetoxy-pancratistatin with dibenzyloxy(N,N-diisopropylamido)phosphine. This pancratistatin prodrug has the structure set forth below: ##STR1##
Alkaloids pancratistatin and narciclasine, isolated from Amaryllidaceae, have been shown to present antitumor activity on preclinical models, including melanoma. Despite extensive investigations, pancratistatin or narciclasine analogues did not succeed to provide sufficient therapeutic benefit, [1] mostly hampered by poor water solubility and systemic toxicity [1]. To overcome those limitations, we developed a chemistry program aimed at improving both their physicochemical and pharmacological properties. A literature survey suggests that any structural modification of this highly oxigenated isocarbostiryl specific scaffold would lead to a loss of activity except on position 1, difficult to achieve but interesting to explore.. A series of 40 novel 1-aminopancratistatin derivatives was synthesised starting from large quantities of narciclasine extracted from Narcissus bulbs. These novel compounds exhibit an improved pharmaceutical profile facing standard solubility, plasmatic and microsomal ...
Description from Flora of China. Herbs perennial, rarely shrubby or treelike, often with bulbs, corms, rhizomes, or tubers. Leaves basal or cauline, often narrow, margin entire or spiny. Inflorescence a terminal spike, umbel, raceme, panicle, or flowers solitary. Flowers bisexual, actinomorphic or zygomorphic, usually subtended by 1 to several spathaceous involucres. Perianth segments 6, in 2 whorls, free or connate to form a short tube, with or without a corona. Stamens 6, inserted at perianth throat or at base of segments; filaments sometimes basally connate; anther dorsifixed or basifixed, mostly introrse. Ovary inferior, 3-loculed; ovules few to many per locule; placentation axile. Style slender; stigma capitate or 3-lobed. Fruit a capsule, usually loculicidal, sometimes dehiscing irregularly, rarely a berry. Seeds with endosperm.. Qian Xiao-hu, Chen Sing-chi, Hsu Yin, Hu Zhi-bi, Huang Xiu-lan & Fan Quan-jin. 1985. Amaryllidaceae. In: Pei Chien & Ting Chih-tsun, eds., Fl. Reipubl. Popularis ...
Pancratieae are a small European tribe of subfamily Amaryllidoideae (family Amaryllidaceae), consisting of two genera including the type genus, Pancratium. The placement of Pancratieae within subfamily Amaryllidoideae is shown in the following cladogram: Two genera: Pancratium Vagaria Anal. Fam. Pl.: 58. 1829. Meerow et al 2006a. Meerow A. 1995. Towards a phylogeny of the Amaryllidaceae. In P. J. Rudall, P. J. Cribb, D. F. Cutler, and C. J. Humphries [eds.], Monocotyledons: systematics and evolution, 169-179. Royal Botanic Gardens, Kew. Müller-Doblies, U.; Müller-Doblies, D. (1996). "Tribes and subtribes and some species combinations in Amaryllidaceae J St Hil R Dahlgren & al. 1985". Feddes Repertorium. 107 (5-6): S.c.1-S.c.9. Meerow A. and D. A. Snijman. 1998 Amaryllidaceae. In K. Kubitzki [ed.], Families and genera of vascular plants, vol. 3, 83-110. Springer-Verlag, Berlin. Meerow, Alan W. Michael F. Fay, Charles L Guy, Qin-BaoLi, Faridah Q Zaman and Mark W. Chase. 1999 Systematics of ...
Galantheae es una tribu perteneciente a la familia Amaryllidaceae. Incluye los géneros Acis, Galanthus, Hannonia, Lapiedra, Leucojum. Galanthus y Leucojum son dos géneros popularmente conocidos en jardinería. USDA, ARS, National Genetic Resources Program. Germplasm Resources Information Network - (GRIN) [Base de Datos en Línea]. National Germplasm Resources Laboratory, Beltsville, Maryland. URL: http://www.ars-grin.gov/cgi-bin/npgs/html/family.pl?2570 (24 June 2014) Müller-Doblies, D., and U. Müller-Doblies. 1978. Studies on tribal systematics of Amaryllidaceae. 1 The systematic position of Lapiedra Lag.. Lagascalia 8: 13-23. Meerow A. 1995. Towards a phylogeny of the Amaryllidaceae. In P. J. Rudall, P. J. Cribb, D. F. Cutler, and C. J. Humphries [eds.], Monocotyledons: systematics and evolution, 169-179. Royal Botanic Gardens, Kew. Müller-Doblies, D., and U. Müller-Doblies. 1996 Tribes and subtribes and some species combinations in Amaryllidaceae J. St.-Hil. emend. R. Dahlgren and al. ...
Pictures of amaryllidaceae wildflowers of West USA. Largeflower onion, Fort Bowie National Historic Site, southeast Arizona. High resolution version
Except where otherwise noted, content on this site is licensed under a Creative Commons Attribution, Non-Commercial, Share Alike CC BY-NC-SA Licence.. ...
Pictures of amaryllidaceae wildflowers of West USA. Stems and narrow basal leaves - allium cernuum along the Snow Pass Trail, Yellowstone National Park, Wyoming. High resolution version
Interests in the field of plant cell culture development, preferably from medicinal plants, induction of bioactive natural product biosynthesis, identification, isolation, purification. Developed radio- and enzymeimmunoassays for the quantitation of Galanthamine, an Amaryllidaceae alkaloid with potent reversible acetylcholinesterase inhibiting activity. Galanthamine HBr is commercially available as Nivalin®. Established immunoassays for quantitation of Colchicine, which is a water soluble alkaloid with cytotoxic activity, present in several species of Liliaceae. Isolated soil microorganisms capable of highly efficient regioselective demethylation at C-3 of the Colchicine structure - an important reaction toward semi-synthetical modification of the molecule, aimed to the synthesis of less toxic derivatives ...
One of the biggest hurdles in the fight against cancer is the non‐selective nature of most current treatments. On the other hand, opioids‐refractive cancer pain is a most important unsolved problem. Consequently, the search and development of new drugs that are tumor‐killing (while non‐cytotoxic to normal cells) and/or potent analgesics are major goals in cancer research. In this context, pancratistatin and tetrodotoxin, the most prominent representatives of two different families of natural products, have been identified as highly promising leads for cancer treatment and cancer pain, respectively; in fact, they are currently at the focus of some initiatives for pharmaceutical development.. Interest in pancratistatin stems from its high level of in vitro and in vivo cell growth inhibitory activity on a wide variety of human cancer cell lines, but particularly from its mode of action that, while yet unknown, is very selective: pancratistatin does not affect normal cells in clear contrast ...
Løkfamilien (Amaryllidaceae) er en plantefamilie i ordenen Asparagales. I APG III og APG IV-systemene er familien utvidet i forhold til eldre systematikk ved at tre eldre familier Agapanthaceae, Alliaceae (løkfamilien i snever betydning) og Amaryllidaceae (narsissfamilien) er slått sammen. Artsdatabanken har valgt å kalle den utvidede Amaryllidaceae for løkfamilien, ikke narsissfamilien. Artene er for det meste flerårige urter med løk. Bladene er linjeformede, og blomstene er tvekjønnede, symmetriske og sitter i skjermer på stilken. Amaryllidoideae har oversittende blomster, mens de to andre underfamiliene har undersittende blomster. De er utbredt i de fleste landområder. Alle arter som vokser naturlig i Norge, tilhører løkslekta (Allium). Familien omfatter mange prydplanter og grønnsaker. ...
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dependent on fire to flower. Like most members of the Amaryllidaceae, the seeds have a characteristic black or blue crust of the ... is the new name for two species of bulbs belonging in the Amaryllidaceae family. These plants were previously thought to be of the genus .... ...
Nuclear DNA content (2C) is used as a new criterion to investigate nearly all species of the genus Nerine Herb. The species have the same chromosome number (2n = 2x = 22), with the exception of three
Strumariinae is one of four subtribes within the tribe Amaryllideae (subfamily Amaryllidoideae, family Amaryllidaceae), found in southern Africa. The leaves are often prostrate (on the ground). The flowers may be zygomorphic or actinomorphic, and may or may not have a perigone tube. The stamens are connate (fused) into a tube at their proximal end. However Strumaria has one whorl of the stamens fused to the style. The fruit is dehiscent with seeds that have a well-developed integument that is chlorophyllous with a stomatose testa. Strumariinae are placed within Amaryllideae as follow: These are phylogenetically related as follows: Strumariinae consists of six genera, related as follows, with number of species in each genus in (parentheses): Bot. Jahrb. 107: 18. 1985 emend Meerow & Snijman, 2001 Meerow & Snijman 2001. Vigneron 2008. Müller-Doblies, U.; Müller-Doblies, D. (1996). "Tribes and subtribes and some species combinations in Amaryllidaceae J St Hil R Dahlgren & al. 1985". Feddes ...
Root bulbous (in all European genera). Leaves radical.; Perianth petal-like, with 6 segments. Stamens 6, the anthers turned inwards. Ovary 3-celled, inferior or adherent to the perianth-tube. Fruit a ...
RESULTS. The analyzed parameters are summarized in Table II. Mitotic metaphases and diploid karyotypes of the species are shown in Figures 1 and 2, respectively.. All seven accessions analyzed showed a common karyotype constitutedby eight chromosome pairs of different sizes and the common karyotype formula was 4m + 10sm + 2st. In most of the taxa, the longest pair corresponded to the first metacentric pair and the shortest pair was the sixth pair (submetacentric) (Table II). The shortest chromosomes were observed in P. aff. davidii and P. lutea, while the longest chromosomes were found in P. amoena. Chromosomes of P. amoena were 30% longer than chromosomes of P. aff. davidii.. For TCL, ANOVA discriminated among taxa (F= 18.22 5, P , 0.001). Considering the CL of each chromosomal pair, all the chromosomal pairs were different among taxa (Table II). In all the assessments, with exception of the seventh and eighth chromosome pairs, P. amoena was different from each other species. In general, the ...
Two low-molecular-weight fractions of sodium hyaluronate (Na-HA), denominated Hyalastin® and Hyalectin®, were investigated as potential adjuvants for ophthalmic vehicles containing pilocarpine nitrate (PiN). Tests were also performed on an ionic complex (HA/PiB) prepared from hyaluronic acid (derived from Hyalastin®) and pilocarpine base. The performance of the vehicles under study was verified by miosis and ocular retention tests carried out on albino rabbits, against a series of reference vehicles, three of which contained a high-molecular-weight fraction of Na-HA (Healon®). The group of 14 reference and test preparations exhibited Newtonian or pseudoplastic flow characteristics and encompassed a wide range of apparent viscosities (1 to 1054 mPa s). The results indicate that the HA/PiB salt and the high-MW Na-HA can significantly increase the bioavailability of pilocarpine with respect to reference vehicles of comparable viscosity: an effect that can be reasonably attributed to ...
white yellow blue brown red white flowers Amaryllidaceae Allium haematochiton Red-Skinned Onion Feb-Apr Asparagaceae Chlorogalum pomeridianum Waxy leaved soap lily Apr-July Hesperoyucca whipplei Chaparral yucca Apr-Aug Liliaceae Calochortus albus White fairy lantern Mar-July Calochortus catalinae Catalina Mariposa Lily Feb-June Calochortus venustus Butterfly Mariposa lily Apr-June Melanthiaceae Toxicoscordion fremontii Star Lily Feb-July Orchidaceae Epipactis gigantea Stream…
As the plots have emptied Matthew and I have replanted them. We have planted winter hardy varieties to feed us early in the following season. In the crop rotation beds the Solanaceae and Cucurbitaceae plants (potatoes and courgettes) have gone. They have been replaced by next years crop of Amaryllidaceae and Fabaceae plants (garlic, onions, peas and beans).. We have planted garlic Picardy Wight. Other good varieties we have grown here at the Garden include Vallelado and Early Purple Wight. We have also planted broad beans Super Aquadulce. Many visitors argue its not worth bothering with autumn sown broad beans. I disagree, it is worth it if only to have something planted in the soil. It can provide winter protection to the soil. It is also a nitrogen fixing plant and useful in crop rotations and managing soil fertility.. ...
Zephyranthes candida produces small daisy like flower sprouting from clumps of small bulbs. The flowers close up at night and open during the day. This makes an attractive border plant.. ...
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Buy Unbeaten Tracks in Japan (Dodo Press) by Professor Isabella Lucy Bird (9781406592054) from Boomerang Books, Australias Online Independent Bookstore
Looking for online definition of lycorine in the Medical Dictionary? lycorine explanation free. What is lycorine? Meaning of lycorine medical term. What does lycorine mean?
Allcosmeticsource.com Galanthamine Hydrobromide(Lycoris P.E.) 98%/Galanthamine HBr, 100gram/bag [257]- Galanthamine Hydrobromide(Lycoris P.E.)99%/Galanthamine HBr, 100gram/bag(N.W. 100grams) Product Name: Galanthamine Hydrobromide Original Plant: Shorttube Lycoris Appearance: White to whitish crystal powder Specification: 99%min. Synonym(s): Reminyl, Nivalin Chemical name: (4aS,6R,8aS)-6-Hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-e,f][2]benzazepine hydrobromide Test Method: HPLC Molecular Formula: C17H21NO3.HBr; C17H22BrNO3 Molecular Weight: 368.27 CAS No.:1953-04-4 Packing size: 100gram/bag, 500gram/carton, or according to the
China High Purity Natural 99% Galantamine Hydrobromide, Find details about China Galantamine Hydrobromide, Lycoris Radiata Extract from High Purity Natural 99% Galantamine Hydrobromide - Shaanxi Yi An Biological Technology Co., Ltd.
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Sixteen more Amaryllidaceae alkaloids have been isolated from bulbs of Crinum kirkii Baker of which noraugustamine and 4a,N-dedihydronoraugustamine are hitherto unknown. Their structures and those of earlier known alkaloids have been established by physical and spectroscopic analysis. Application of 2D NMR techniques was used for complete characterization of the alkaloids as well as of 3-O-acetylsanguinine. 1,2-Diacetyllycorine and 3-O-acetylsanguinine showed activity against Trypanosoma brucci rhodesiense, the parasite associated with sleeping sickness. 3-O-acetylsanguinine also showed some activity against Trypanosoma cruzi ...
Lycoris species have been known since long ago as a multi-utility ethnomedicinal herbal in China. It has been reported to exhibit a number of properties such as anticancer, neuroprotective, and antibacterial activities. In the present study, the anticancer efficacy of dichloromethane extracts of Lycoris aurea (DELA), was evaluated both in vivo and in vitro using murine sarcoma 180 cells. To evaluate the effects of DELA on apoptotic cell death, flow cytometry and Western blotting were performed. DELA demonstrated promising inhibition effects on sarcoma 180 cells in vitro and a 53.49% inhibitory rate on cancer cells in vivo. DELA treatment increased thymus indices and spleen indices in vivo, indicating that it reduced tumours, but did not damage the main immune organs. The DELA-evoked increase in apoptotic cell death was accompanied by occurrence of cleaved caspase-3 and decreases in the ratio of Bcl-2/Bax. Further purification and LCMS analysis showed DELA contained homolycorine, 2α-hydroxyoduline,
Graell, Antònia Roselló; Isabel (1 de janeiro de 2003). «Segunda localidad de Narcissus cavanillesii A. Barra & G. López (Amaryllidaceae) para Portugal». Acta botánica malacitana (28): 196-197. ISSN 0210-9506 A referência emprega parâmetros obsoletos ,coautores= (ajuda) Marques, Isabel; Antònia Roselló (1 de janeiro de 2009). «Narcissus cavanillesii en la Cuenca del Guadiana: hacia una conservación transfronteriza». Acta botánica malacitana (34): 269-272. ISSN 0210-9506 A referência emprega parâmetros obsoletos ,coautores= (ajuda) Marques, Isabel; Antònia (1 de agosto de 2007). «Pollination patterns limit hybridization between two sympatric species of Narcissus (Amaryllidaceae)». American Journal of Botany. 94 (8): 1352-1359. ISSN 0002-9122. PMID 21636503. doi:10.3732/ajb.94.8.1352 A referência emprega parâmetros obsoletos ,coautores= (ajuda) Marques, Isabel; Gonzalo Nieto (1 de agosto de 2010). «Unraveling Cryptic Reticulate Relationships and the Origin of Orphan Hybrid ...
Lo scalogno persiano (Allium stipitatum Regel, 1881) è una specie della famiglia delle Liliaceae (attribuita alle Amaryllidaceae dalla classificazione APG), originaria dei monti Zagros nella regione del Kurdistan. ^ The Angiosperm Phylogeny Group, An update of the Angiosperm Phylogeny Group classification for the orders and families of flowering plants: APG II, in Botanical Journal of the Linnean Society 2003; 141: 399-436. ^ Allium stipitatum, in World Checklist of Amaryllidaceae, Board of Trustees of the Royal Botanic Gardens, Kew. URL consultato il 28 gennaio 2012. Specie di Allium Altri progetti Wikimedia Commons Wikispecies Wikimedia Commons contiene immagini o altri file su Allium stipitatum Wikispecies contiene informazioni su Allium ...
Pseudonarcissi es una sección de plantas bulbosas perteneciente al género Narcissus dentro de la familia de las amarilidáceas.[1]​ Narcissus abscissus (Haworth) Schultes & Schultes f. Narcissus albescens Pugsley Narcissus alcaracensis Ríos, D.Rivera, Alcaraz & Obón Narcissus alpestris Pugsley Narcissus asturiensis (Jordan) Pugsley Narcissus bicolor L. Narcissus confusus Pugsley Narcissus enemeritoi (Sánchez-Gómez, Carrillo, Hernández, Carrión-Vilches & Güemes) Sánchez-Gómez, Carrillo, Hernández, Carrión-Vilches & Güemes Narcissus fontqueri Fernández Casas & Rivas Ponce Narcissus gayi Pugsley Narcissus hispanicus Gouan subsp. hispanicus subsp. bujei (Fernández Casas) Fernández Casas, Narcissus jacetanus Fernández Casas subsp. jacetanus subsp. vasconicus (Fernández Casas) Fernández Casas Narcissus lagoi Merino Narcissus lobularis (Haworth) Schultes & Schultes f. Narcissus longispathus Pugsley Narcissus macrolobus (Jordan) Pugsley Narcissus minor L. Narcissus moleroi ...
Tropica sells Hemigraphis :). ----------------- Louis Lin TickQuest Inc www.tickquest.com ----- Original Message ----- From: piaba ,piabinha at yahoo_com, To: ,aquatic-plants at actwin_com, Sent: Thursday, February 26, 2004 5:05 PM Subject: [APD] Zephyranthes candida , oh my god, i cannot believe people would sell a , terrestrial plant as an aquarium plant. what is the , world coming to???? :-) , , thanks, nick. im familiar with the genus , Zephyranthes but i just assumed this was perhaps an , aquatic member of the genus, as are some Crinum. , , tsuh yang , , , If I were you, Id pot up the Zephyranthes candida , , and put it on your windowsill. , , Cultural notes here: , , http://www.paghat.com/rainlily.html , , , __________________________________ , Do you Yahoo!? , Get better spam protection with Yahoo! Mail. , http://antispam.yahoo.com/tools , _______________________________________________ , Aquatic-Plants mailing list , Aquatic-Plants at actwin_com , ...
Stock images and information on Naked Lady, Surprise Lily, Resurrection Lily, Magic Lily, Lu cong, Lycoris squamigera, Amaryllis hallii, Photos by Steven Foster, Steven Foster Group, Inc., Eureka Springs, Arkansas
Narcissus: Narcissus, (genus Narcissus), genus of about 40 species of bulbous, often fragrant, plants in the amaryllis family (Amaryllidaceae). The genus is native primarily to Europe and includes a number of garden ornamentals such as daffodil (or trumpet narcissus, Narcissus pseudonarcissus), jonquil (N.
Narcissus × odorus - Checklist da Flora de Portugal (Continental, Açores e Madeira) - Sociedade Lusitana de Fitossociologia Checklist da Flora do Arquipélago da Madeira (Madeira, Porto Santo, Desertas e Selvagens) - Grupo de Botânica da Madeira Narcissus × odorus - Portal da Biodiversidade dos Açores Narcissus × odorus - The Plant List (2010). Version 1. Published on the Internet; http://www.theplantlist.org/ (consultado em 29 de setembro de 2014). Narcissus × odorus - International Plant Names Index Castroviejo, S. (coord. gen.). 1986-2012. Flora iberica 1-8, 10-15, 17-18, 21. Real Jardín Botánico, CSIC, Madrid. Narcissus × odorus - Flora Digital de Portugal. jb.utad.pt/flora. Narcissus × odorus - Flora-on Narcissus × odorus - The Euro+Med PlantBase Narcissus × odorus - Flora Vascular Narcissus × odorus - Biodiversity Heritage Library - Bibliografia Narcissus × odorus - JSTOR Global Plants Narcissus × odorus - Flora Europaea Narcissus × odorus - NCBI Taxonomy Database ...
Gliomas are the most common primary brain tumors. Of these, glioblastoma multiforme (GBM) is the most malignant; characterized by its heterogeneity and aggressive invasive behavior into normal brain tissue. Cell motility and resistance to apoptosis characterize GBM growth and malignancy. Narciclasine is a plant growth modulator isolated from Narcissus bulbs which has been shown to exhibit inhibitory effects on a wide range of plant growth aspects including seed germination, seedling growth, the growth and plastid development of excised radish cotyledons and chloroplast development. We have recently shown that narciclasine at 1µM in vitro induces marked apoptosis-mediated cytotoxicity in certain human cancer cell lines but not in normal fibroblasts. This cytotoxicity is triggered by the activation of initiator caspases in the death receptor pathway (caspases 8 & 10) at least in human MCF-7 breast and PC3 prostate carcinoma cells. However, the compound failed to induce apoptosis in GBM cells. ...
In chronic heart failure (CHF), the heart muscle does not pump blood well enough to meet the bodys need for blood and oxygen. CHF is caused by high blood pressure, coronary artery disease, and other cardiovascular conditions. It is a common cause of death in older people. Garlic (Allium sativum, Amaryllidaceae) bulb has been shown…
In high summer Crinums are often seen blooming in old Southern gardens. Like their cousins amaryllis, crinums are also within the Amaryllidaceae family. Blooming still In abandoned gardens they may...
Cite this page: "Crinum cordofanum" Text available under a CC-BY-SA Creative Commons Attribution License. www.llifle.com 14 Nov. 2005. 17 Nov 2017. ,/Encyclopedia/BULBS/Family/Amaryllidaceae/29714/Crinum_cordofanum ...
TopTropicals exotic plant encyclopedia. Plant%20profile%20-%20Species:%20Crinum%20sp.%2c%20Botanical%20Family:%20Amaryllidaceae%2c%20Plant%20common%20name:%20River%20Lily%2c%20Plant%20origin:%20Australia%2c%20tropical%20Asia%2c%20South%20Africa
Laglio napoletano (Allium neapolitanum) è una specie della famiglia delle Liliaceae (o Amaryllidaceae secondo la classificazione APG), endemica delle Alpi e degli Appennini. ^ Angiosperm Phylogeny Group, An update of the Angiosperm Phylogeny Group classification for the orders and families of flowering plants: APG III, in Botanical Journal of the Linnean Society 2009; 161(2): 105-121. Specie di Allium Altri progetti Wikimedia Commons Wikispecies Wikimedia Commons contiene immagini o altri file su Allium neapolitanum Wikispecies contiene informazioni su Allium neapolitanum (FR) Ail à fleurs de narcisse, in Flore des Hautes-Alpes ...
Botanical Name : Allium scorodoprasum rotundum Family: Amaryllidaceae Subfamily: Allioideae Tribe: Allieae Genus: Allium Kingdom: Plantae Order: Asparagales
Botanical Name: Allium obliquum Family: Amaryllidaceae Subfamily: Allioideae Tribe: Allieae Genus: Allium Species: A. obliquum Kingdom: Plantae Order:
OSNews is Exploring the Future of Computing with news on desktop, server, mobile, and specialty operating systems and new computing technology.
Previous studies have demonstrated that microinjections of the α2-AR agonist guanabenz produce dose-dependent vasodepressor responses (Lim et al., 1985). It has also been shown that the systemic vasodepressor effects of guanabenz could be blocked by local application of the α2-AR antagonist yohimbine into the gigantocelluar reticular formation (Lim et al., 1988), supporting the idea that α2-ARs in the gigantocelluar reticular formation participate in the vasodepressor actions of α2-AR agonists (Chen and Chan, 1980; Lim and Chan, 1986). The present results extend these findings to show that local application of an even more potent antihypertensive agent, clonidine, can produce dose-dependent falls in arterial pressure after the application of volumes and doses (20 nl volume, 750 pmol total dose) that are a fraction of the volumes used in many other studies. These results also show that the vasodepressor and bradycardic responses to clonidine can be completely blocked in a dose-dependent ...
Definition of Narcissus in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is Narcissus? Meaning of Narcissus as a legal term. What does Narcissus mean in law?
The orientation of the organofibrous structure plays an important role not only in the biomineralization process but also in the extracellular matrix (ECM) of articular cartilage by providing cells with biomechanical cues. Here, it is reported that a long range nanofibrous orientation can be realized by a self-assembling ionic complex between (+)-charged amphiphilic peptide block copolymers with a rigid-flexible block structure (polyalanine-PLX-polyalanine; PA-PLX-PA) and (-)-charged hyaluronic acid (HA). A biomimetic 3D culture system encapsulating chondrocytes is formed by a temperature-sensitive sol-to-gel transition of the PA-PLX-PA/HA complex aqueous solution, which provides a compatible microenvironment for the cells. The cell proliferation and biomarker expression for articular cartilage are significantly improved in the PA-PLX-PA/HA complex system relative to the PA-PLX-PA or the commercially available Matrigel systems. In particular, noticeable cell clustering is observed in the ...
A memory cell is provided with a pair of electrodes, and an active layer sandwiched between the electrodes and including a molecular system and ionic complexes distributed in the molecular system. The active layer having a high-impedance state and a low-impedance state switches from the high-impedance state to the low-impedance state when an amplitude of a writing signal exceeds a writing threshold level, to enable writing information into the memory cell. The active layer switches from the low-impedance state to the high-impedance state when an amplitude of an erasing signal having opposite polarity with respect to the writing signal exceeds an erasing threshold level, to enable erasing information from the memory cell.
Narcissus Wallpaper Originals provides free original Nature - Flowers Narcissus - desktop wallpapers for Mac & PC. ALL Narcissus Wallpapers @ Wallpaper Originals are 100% FREE & ORIGINAL!
name conserved] Rain-lily, fairy-lily, zephyr-lily [Greek Zephyros, west wind, and anthos, flower] Raymond O. Flagg, Gerald L. Smith & Walter S. Flory† Atamosco Adanson 1763, name rejected; Cooperia Herbert. Herbs, perennial, scapose, from bulbs. Bulbs black or brown, tunicate, ovoid or globose, sometimes with long neck. Leaves sessile, erect or recumbent, with overlapping sheathing bases; blade linear, rarely exceeding 1 cm wide, smooth. Scape hollow. Inflorescence 1-flowered (rarely 2-flowered in Z. drummondii), spathaceous, otherwise ebracteate; spathe proximally tubular. Flowers erect to declinate, actinomorphic; perianth subrotate to funnelform to salverform, connate basally into tube, 2-16 cm; tepals subequal; stamens 6, of 2 different lengths, appearing equal or subequal (anthers in 2 overlapping sets of 3) to unequal (anthers of the sets not overlapping in Z. longifolia); filaments inserted just above perianth tube, erect, diverging except when shorter than tube, long-filiform to ...
The Atlas of Florida Plants provides a source of information for the distribution of plants within the state and taxonomic information. The website also provides access to a database and images of herbarium specimens found at the University of South Florida and other herbaria.
Welcome to my personal plant/design directory. I try my best to be curious. I love photographing nature. As a tutor, I feel there is a need to equip myself with necessary information so I wont mislead my students. We are all students & we are all educators to one another. Lets not mis-educate each other :) ...
A good horticulture therapy exercise is the forcing of narcissus bulbs...as they awaken more than one sense! Narcissus are great because they do not require advance chilling to get the bulbs to bloom indoors. This is an activity that uses gross motor movements, has a low cost, low maintenance, and quick results. I picked up 2 boxes of paperwhite narcissus that were on the clearance table at Lowes(pictured below) and proceeded to awake the magic that is locked up inside by following the instructions written on the outside of the box ...
Englisch ⇔ Deutsch: small narcissus flies bersetzung Englisch zu Deutsch ✐ Alle bersetzungen f r das Wort small narcissus flies
Complete summary of Hermann Hesses Narcissus and Goldmund. eNotes plot summaries cover all the significant action of Narcissus and Goldmund.
Read 4. NARCISSUS OFF DUTY of This Side of Paradise by F. Scott Fitzgerald. The text begins: BOOK ONE The Romantic Egotist CHAPTER 4 Narcissus Off Duty DURING Princetons transition period, that is, during Amorys last two years there, while he saw it change and broaden and live up to its Gothic beauty by better means than night parades, certain individuals arrived who stirred it to its plethoric depths. Some of them had been freshmen, and wild freshmen, with Amory; some were in the class below; and it was in the beginning of his last year and around small tables at the Nassau Inn that they began questioning aloud the institutions that Amory and countless others before him had questioned so long in secret. First, and partly by accident, they struck on certain books, a definite ...
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Species: N. albimarginatus - N. atlanticus - N. calcicola - N. cuatrecasasii - N. marvieri - N. rupicola - N. scaberulus - N. watieri. Name. Narcissus sect. Apodanthi A. Fernandes. ...
See Mac apps for narcissus. Download, install, and explore always updated Mac apps. Find your new favorite Mac app today at MacUpdate!
It is a time of rejoicing amongst the thought-commune known as Deus Ex fans. The Narcissus Entity has deigned to break its silence and - once again -
Mårten Mickos, CEO of MySQL, recently shared his thoughts on why MySQL decided to join Sun rather than continuing towards an IPO. Interesting reading, though I suggest running it through sed /\!/\./g first. Read it here.
AMD gave away this booklet at their Supercomputing 06 booth. Its a marketing blurb and not a technical document, but it does cover the basics of the value proposition at a high level. I have a few copies if anyone (at Sun) is interested in taking a look.
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Allcosmeticsource.com Galanthamine Hydrobromide(Lycoris P.E.)98%/Galanthamine HBr, 100gram/bag [257]- Galanthamine Hydrobromide(Lycoris P.E.)98%/Galanthamine HBr, 100gram/bag Product Name: Galanthamine Hydrobromide Original Plant: Shorttube Lycoris Appearance: White to whitish crystal powder Specification: 99%min. Synonym(s): Reminyl, Nivalin Chemical name:(4aS,6R,8aS)-6-Hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-e,f][2]benzazepine hydrobromide Test Method: HPLC Molecular Formula: C17H21NO3.HBr;C17H22BrNO3 Molecular Weight: 368.27 CAS No.:1953-04-4 Packing size: 100gram/bag, 500gram/carton, 25 kg/barrel or according to the customer request Pharmacology Action: Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is
Background and Aims. Although there is evidence that both allopolyploid and homoploid hybridization lead to rapid genomic changes, much less is known about hybrids from parents with different basic numbers without further chromosome doubling. Two natural hybrids, Narcissus × alentejanus (2n = 19) and N. × perezlarae (2n = 29), originated by one progenitor (N. cavanillesii, 2n = 28) and two others (N. serotinus, 2n = 10 and N. miniatus, 2n = 30, respectively) allow us to study how DNA content and composition varies in such hybrids.. Methods. Flow cytometry measurements with two staining techniques, PI and DAPI, were used to estimate 2C values and base composition (AT/GC ratio) in 390 samples from 54 wild populations of the two natural hybrids and their parental species. In addition, 20 synthetic F1 hybrid individuals were also studied for comparison.. Key Results. Natural hybrids presented 2C values intermediate between those found in their parental species, although intra-population variance ...
We get a lot of questions about flower bulbs, but most involve when to plant them. Quite simply, fall flower bulbs are planted in the fall, grow roots into winter, then sprout and bloom in the spring. These include favorites such as tulips, daffodils, hyacinth and others. Spring flower bulbs are also known as tender bulbs (they dont survive cold ground temperatures); theyre planted in the spring and flower throughout the summer. They include dahlias, glads, cannas, calla lilies and others.
We get a lot of questions about flower bulbs, but most involve when to plant them. Quite simply, fall flower bulbs are planted in the fall, grow roots into winter, then sprout and bloom in the spring. These include favorites such as tulips, daffodils, hyacinth and others. Spring flower bulbs are also known as tender bulbs (they dont survive cold ground temperatures); theyre planted in the spring and flower throughout the summer. They include dahlias, glads, cannas, calla lilies and others.
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc. Health benefits 1. Anti cancer In the evaluation of Garlic (Allium …. ...
2-propenesulfenic acid, AGE, aged garlic extract, aglio (Italian), aglio commune (Italian), ail (French), ail blanc (French), ail commun (French), ail cultiv (French), ail de printemps (French), ail rose sans b ton (French), ajo (Spanish), ajo com n (Spanish), ajo vulgar (Spanish), ajoene, akashneem, alho (Portuguese - Portugal, Portuguese - Brazil), ), alho-bravo (Portuguese - Brazil), alho-comum (Portuguese - Brazil), alho-hortense (Portuguese - Brazil), alisat, alk(en)yl thiosulfates, Alliaceae (family), allicin, Allicor (a long-action, garlic-based preparation), Allii sativi bulbus, alliinase, allitridium, allium, allyl mercaptan, Alterswurzel (German), alubosa elewe, Amaryllidaceae (family), ayo-ishi, ayu, banlasun, bawang (Tagalog), bawang bodas (Sundanese), bawang puteh (Malay), bawang putih (Malay - Indonesia, Malay - Java), beli luk (Serbian), bellulli (Kannada), bhabang pot (Madurese), ca suan (Chinese), ca suan tou (Chinese), camphor of the poor, cesen (Slovenian), cesnak kuchynsk ...
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Open Access (290) the Searching for Lost Frogs (5) Worlds Smallest Frogs (2) 1800s (3) 1910s (2) 1930s (2) 1940s (1) 1950s (2) 1960s (5) 1970s (3) 1980s (19) 1991 (6) 1992 (2) 1993 (5) 1994 (6) 1995 (12) 1996 (8) 1997 (13) 1998 (18) 1999 (30) 2000 (19) 2001 (25) 2002 (35) 2003 (39) 2004 (41) 2005 (68) 2006 (68) 2007 (79) 2008 (108) 2009 (128) 2010 (157) 2011 (196) 2012 (237) 2013 (366) 2014 (384) 2015 (418) 2016 (668) 2017 (914) 2018 (142) Abelisaur (6) Abelisauridae (6) Acanthaceae (4) Acanthuridae (1) Acanthuriformes (1) Accipitridae (4) Acoustics (37) Acta Phytotax. Geobot. (2) Actinopterygii (67) Advertisement Call (18) Aepyornithidae (1) Aetiocetidae (1) Aetosaur (1) Afghanistan (1) Africa (321) African Amphibian (35) African Bird (18) African Botany (20) African Fish (25) African Great Lakes (1) African Invertebrates (10) African Mammal (39) African Reptile (48) Afromontane (9) Afrotheria (1) Afrotropic (28) Agamidae (55) Agaricales (2) Akysidae (3) Algeria (1) Alligatoridae (1) ...
Open Access (245) the Searching for Lost Frogs (5) Worlds Smallest Frogs (2) 1800s (3) 1910s (2) 1930s (2) 1940s (1) 1950s (2) 1960s (5) 1970s (3) 1980s (19) 1991 (6) 1992 (2) 1993 (5) 1994 (6) 1995 (12) 1996 (8) 1997 (13) 1998 (18) 1999 (30) 2000 (19) 2001 (25) 2002 (34) 2003 (38) 2004 (41) 2005 (67) 2006 (68) 2007 (78) 2008 (107) 2009 (126) 2010 (156) 2011 (196) 2012 (237) 2013 (366) 2014 (380) 2015 (417) 2016 (658) 2017 (647) Abelisaur (6) Abelisauridae (6) Acanthaceae (4) Acanthuridae (1) Acanthuriformes (1) Accipitridae (4) Acoustics (36) Acta Phytotax. Geobot. (1) Actinopterygii (50) Advertisement Call (15) Aepyornithidae (1) Aetiocetidae (1) Aetosaur (1) Africa (284) African Amphibian (29) African Bird (18) African Botany (14) African Fish (22) African Great Lakes (1) African Invertebrates (3) African Mammal (36) African Reptile (42) Afromontane (9) Afrotheria (1) Afrotropic (22) Agamidae (54) Agaricales (1) Akysidae (3) Alligatoridae (1) Allosaur (1) Alsodidae (1) Amaryllidaceae ...
0100] The ability of toothpaste formulations containing superloaded CPP-ACP (sCPP-ACP) to remineralize enamel sub-surface lesions was investigated in a randomized, cross-over, double-blind in situ clinical study using the protocol of Reynolds et al. [Reynolds E. C. et al., (2003) J Dent Res. 82, 206-211]. Ten subjects wore removable palatal appliances with six, human enamel, half-slabs containing sub-surface demineralized lesions prepared as described in Example 3. The other half of each enamel slab was stored in a humidified container and was used as the control demineralized lesion. There were seven treatments in the study, toothpaste B containing 0.2% w/w normal CPP-ACP, toothpaste C containing 0.2% CPP-ACP/1.0% CaHPO4 (referred to in FIG. 2 and Example 5 as "1.2% sCPP-ACP"), toothpaste E containing 1.0% CaHPO4, toothpaste F containing 1000 ppm F, toothpaste G containing 1.2% sCPP-ACP plus 1000 ppmF, toothpaste D containing 0.2% CPP-ACP/1.8% CaHPO4 (referred to in FIG. 2 and Example 5 as ...
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Removal of endothelial cells on rings of rat aorta increased the sensitivity to the selective alpha-1 adrenoceptor agonist phenylephrine, to the nonselective alpha adrenoceptor agonist norepinephrine and to the selective alpha-2 adrenoceptor agonist clonidine. In the case of the first two, which are strong agonists for the alpha-1 adrenoceptor-mediating contraction, removal of endothelium increased sensitivity 4- and 6-fold at the EC30 level, but produced little or no increase in maximum. In the case of clonidine, a partial agonist for the alpha-1 adrenoceptor, which gave only about 15% of the maximum given by phenylephrine on endothelium-containing rings, removal of the endothelium not only shifted the curve to the left but also increased the maximum to about 50% of that given by phenylephrine. The depression of sensitivity to these agonists in rings with endothelium appeared to be due to the vasodepressor action of endothelium-derived relaxing factor (EDRF), as hemoglobin, a specific blocking ...
There are a number of fragrant flower bulbs available, ranging from mildly scented to stronger aromas, making it easy to enhance your garden with a colorful spectrum of fragrant blooms throughout the seasons. - Fragrant Flower Bulbs - Gardening at BellaOnline
Quinolones are synthetic broad-spectrum antibiotics with good oral absorption and excellent bioavailability. Due to the chemical functions found on their nucleus (a carboxylic acid function at the 3-position, and in most cases a basic piperazinyl ring (or another N-heterocycle) at the 7-position, and a carbonyl oxygen atom at the 4-position) quinolones bind metal ions forming complexes in which they can act as bidentate, as unidentate and as bridging ligand, respectively. In the polymeric complexes in solid state, multiple modes of coordination are simultaneously possible. In strongly acidic conditions, quinolone molecules possessing a basic side nucleus are protonated and appear as cations in the ionic complexes. Interaction with metal ions has some important consequences for the solubility, pharmacokinetics and bioavailability of quinolones, and is also involved in the mechanism of action of these bactericidal agents. Many metal complexes with equal or enhanced antimicrobial activity compared to the
Get expert gardening tips on the RAIN LILY, ZEPHYR FLOWER, FAIRY LILY. How much sun, shade, water and care does it need? Read on to find out.
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There were twenty two Plant Heritage members in all at the event hosted at Hullwood Barn on Sunday 2nd of April. Darren Andrews gave an introduction to the International Horticultural Classification system for Daffodils, explaining which species had been used for breeding in each group, and how a knowledge of this is very relevant to the cultivation of Narcissus within each division. Neil Bradfield talked about aesthetic considerations when planting and growing Narcissus, which made everyone think about the plant associations in … Continue reading →. ...
Salvador Dalí, Metamorphosis of Narcissus, 1937, oil on canvas, 51.1 x 78.1 cm (Tate Modern, London). The ancient source of this subject is Ovids Metamorphosis (Book 3, lines 339-507). It tells of Narcissus, who upon seeing his own image reflected in a pool, so falls in love that he cannot look away. Eventually he vanishes and in his place is a "sweet flower, gold and white, the white around the gold.". Dalís poem, below, accompanied the painting when it was initially exhibited:. ...
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Narcissus major. Great Daffodil. Class and Order: Hexandria Monogynia. Generic Character: Petala 6 aequalia: Nectario infundibuliformi, 1-phyllo. Stamina intra nectarium. Specific Character and S...
Plants Images. Biology Encyclopedia. Source: Wikispecies: All text is available under the terms of the GNU Free Documentation License. ...
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Narzissmus und die eigenen Abgründe vom Höhenflug. Das israelische Duo lebt im kalifornischen Exil und hat mit ihrem zweiten Release ein Meisterwerk abgeliefert, das so sperrig, kantig und unvorhersehbar ist, das man getrost das alte Einstürzende Neubauten Motto „Hör mit Schmerzen" bemühen darf ...
/r/TwoDeeArt is a place to post art that you dont feel fits in: - /r/awwnime - /r/pantsu - /r/moescape - /r/patchuu , but you still...
A. stipitatum (Synonym: A. hirtifolium) or Persian shallot from Amaryllidaceae family with indigenous name of Mooseer is one of the important edible Alliums in Iran. It is native and endemic from northwestern to southern of Iran and grows as a wild plant in the Zagross Mountains at high elevations of different provinces with the climate of very cold to moderate cold. In this study, essential oil constituents of A. stipitatum were investigated through gas chromatography/mass spectrometry (GC-MS) technique. After obtaining the chromatograms and mass spectra, the essential compounds of the essential oil were determined. As shown 1-Butene,1-(methylthio)-(Z) (18.21%), Methyl methylthiomethyl disulfide (8.41%), Dimethyl tetrasulfide (6.47%), Piperitenone oxide (4.55%) were the most abundant components and comprised 37.64% of the essential oil (Figure 1). While 2,5-Diethylthiophene (0.07%) and n-Nonanal (0.06%) were detected in lower amounts. The presence of compounds showed mono-sulfur (22.42%), ...
Open Access (245) the Searching for Lost Frogs (5) Worlds Smallest Frogs (2) 1800s (3) 1910s (2) 1930s (2) 1940s (1) 1950s (2) 1960s (5) 1970s (3) 1980s (19) 1991 (6) 1992 (2) 1993 (5) 1994 (6) 1995 (12) 1996 (8) 1997 (13) 1998 (18) 1999 (30) 2000 (19) 2001 (25) 2002 (34) 2003 (38) 2004 (41) 2005 (67) 2006 (68) 2007 (78) 2008 (107) 2009 (126) 2010 (156) 2011 (196) 2012 (237) 2013 (366) 2014 (380) 2015 (417) 2016 (658) 2017 (647) Abelisaur (6) Abelisauridae (6) Acanthaceae (4) Acanthuridae (1) Acanthuriformes (1) Accipitridae (4) Acoustics (36) Acta Phytotax. Geobot. (1) Actinopterygii (50) Advertisement Call (15) Aepyornithidae (1) Aetiocetidae (1) Aetosaur (1) Africa (284) African Amphibian (29) African Bird (18) African Botany (14) African Fish (22) African Great Lakes (1) African Invertebrates (3) African Mammal (36) African Reptile (42) Afromontane (9) Afrotheria (1) Afrotropic (22) Agamidae (54) Agaricales (1) Akysidae (3) Alligatoridae (1) Allosaur (1) Alsodidae (1) Amaryllidaceae ...
definition of narcissus - bulbous plant having erect linear leaves and showy yellow or white flowers either solitary or in clusters
Narcissus pseudonarcissus lectin (NPL) is isolated from daffodils. It exists as a dimeric protein (molecular weight 26 kDa) composed of two subunits of 13 kDa each. NPL dissociates into its monomers below pH 5.0 and above pH 9.0. NPL is mitogenic for human lymphocytes. Specificity for blood group: non-reactive with human erythrocytes. Narcissus pseudonarcissus lectin is supplied as a white lyophilized powder in 10 mM CHsub3COONHsub4. For laboratory use only.
We have demonstrated that GLUT1 protein and intracellular glucose are differentially elevated in neointimal VSMCs compared with medial VSMCs after balloon injury. To understand the link between metabolic signaling and lesion formation, we created cultured VSMCs with constitutive upregulation of GLUT1. Upregulation of GLUT1 resulted in increases in both nonoxidative and oxidative glucose metabolism, as assessed by 13C-NMR spectroscopy. This enhanced glucose transport and utilization was sufficient to inhibit apoptosis induced by serum withdrawal as well as Fas-ligand. The inhibition of apoptosis in response to two mechanistically distinct proapoptotic stimuli suggests a fundamental effect on the final common pathways regulating cell death. The coordinate increase in cell proliferation and decrease in VSMC apoptosis provides a mechanism by which enhanced glucose transport and metabolism may promote vascular lesion formation.. Coincident with the upregulation in GLUT1 expression in neointimal ...
Detail záznamu - Glycosides of benzodioxole-indole alkaloids from Narcissus having axial chirality - Detail záznamu - Knihovna Akademie věd České republiky
Allium spp.are members of the family Amaryllidaceae. This genus consists of over 400 species including: ampeloprasum (leek), cepa (common onion), fistulosum (bunching onion), sativum (garlic), schoenoprasum (common chives), and tuberosum (garlic chives). Alliums have perfect flowers but, can not self-pollinate because the male anthers shed pollen before the female stigma is receptive. Therefore they cross-pollinate via insects (flies and bees) or by manually pollinating (hand-pollinating) the flowers in a controlled environment. Seed producers must keep in mind that varieties of the same species will cross-pollinate with other varieties of the same species. Chives reproduce by division of bulbs and produces seed. To reproduce garlic you must save healthy heads and replant the individual cloves separately. Topsetting or hardneck varieties of garlic will produce a seedhead with bubils. These can be planted, but it will take several successive years to get good-sized heads.. Many alliums (A. cepa) ...
This is the painting Dali took to show Freud in London. It belonged formerly to Edward James." (Caption); "At Zürs […] Dali embarked on a new experiment: the composition, in French, of a paranoaic poem, The Myth of Narcissus, to be concurrently illustrated, word by word, in a painting. […] The subtitle of the poem explained that the latter constituted a way of visually observing the course of the metamorphosis of Narcissus […]. Dalis interest in the Narcissus myth may have been stimulated by Albert Skiras edition of Ovids Metamorphoses, illustrated by Picasso. Given his own, Narcissus-style self-absorption it was hardly surprising that he considered the myth of great personal relevance. In this he was assisted by Freuds Three Essays on Sexuality and, particularly, Psycho-Analytic Notes on an Autobiographical Account of a Case of Paranoia. In the latter Freud uses the term narcissism (defined in The Interpretation of Dreams as the unbounded self-love of children) to ...
Apoptosis is a controlled form of cellular demolition, catalyzed by a family of cysteine proteases called caspases. In response to diverse proapoptotic stimuli, caspase-9 is recruited and activated within an oligomeric complex called the apoptosome. The apoptosome drives autocatalytic processing of caspase-9, triggering a proteolytic caspase cascade that results in the biochemical and morphological changes characteristic of cell death. It is unclear why caspase-9 undergoes autocatalytic processing following apoptosome recruitment, because interdomain processing is dispensable for caspase-9 activity. A study has shed light on this issue by demonstrating that caspase-9 processing within the apoptosome promotes its displacement from the complex, leading to inactivation of this protease. Thus, autoprocessing of caspase-9 within the apoptosome serves as a "molecular timer" that limits the proteolytic activity of this complex through displacement of bound caspase-9 molecules. This timer mechanism may ...
Cet article ou une de ses sections doit être recyclé (février 2007). Une réorganisation et une clarification du contenu paraissent nécessaires. Discutez des points à améliorer en page de discussion ou précisez les sections à recycler en utilisant {{section à recycler}}. Liste des familles dangiospermes. Abolbodaceae Nakai ~ Acanthaceae Juss. ~ Aceraceae Juss. ~ Achariaceae Harms ~ Achatocarpaceae Heimerl. ~ Acoraceae Martinov ~ Actinidiaceae Gilg & Werderm. ~ Adoxaceae E.Mey.~ Aegicerataceae Blume ~ Aextoxicaceae Engl. & Gilg ~ Agavaceae Endl. ~ Agdestidaceae Nak. ~ Aitoniaceae Harv. & Sond. ~ Aizoaceae Rudolphi ~ Akaniaceae Stapf ~ Alangiaceae DC. ~ Alismataceae Vent. ~ Alliaceae Borkh. ~ Alseuosmiaceae Airy Shaw ~ Alstroemeriaceae Dumort. ~ Altingiaceae Lindl. ~ Alzateaceae S.Graham ~ Amaranthaceae Juss. ~ Amaryllidaceae J.St.-Hil. ~ Amborellaceae Pichon. ~ Anacardiaceae Lindl. ~ Anarthriaceae Cutler & Airy Shaw ~ Ancistrocladaceae Planch. ex Walp ~ Androstachydaceae Airy Shaw ~ ...
387460129 - EP 0879596 A3 2000-08-16 - Use of cholinesterase inhibitors to reduce benzodiazepine side effects - [origin: US5336675A] Mania is treated by administering, to a patient in need thereof, galanthamine or a salt or derivative thereof or a functional equivalent of galanthamine, the functional equivalent being an acetylcholinesterase inhibitor which is active substantially selectively at nicotinic receptor sites.[origin: US5336675A] Mania is treated by administering, to a patient in need thereof, galanthamine or a salt or derivative thereof or a functional equivalent of galanthamine, the functional equivalent being an acetylcholinesterase inhibitor which is active substantially selectively at nicotinic receptor sites.
Galantamine Hydrobromide is the hydrobromide salt form of galantamine, a tertiary alkaloid with anticholinesterase and neurocognitive-enhancing activities. It is an alkaloid acetylcholinesterase inhibitor. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). This agent may improve neurocognitive function in mild and moderate Alzheimer s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.

Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-…Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-…

Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity - Detail záznamu - ... belonging to four structural types of Amaryllidaceae alkaloids, were identified and quantified by GC-MS. The alkaloid extract ... Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity. *. 1.. 0346356 - ... Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity. Natural Product ...
more infohttps://asep.lib.cas.cz/arl-cav/sk/detail-cav_un_epca-0346356-Analysis-of-Amaryllidaceae-Alkaloids-from-Zephyranthes-robusta-by-GCMS-and-Their-Cholinesterase-Act/

Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors<...Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors<...

Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors. En: ... Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors. / Cortes ... Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors. ... Cortes, N, Sierra, K, Tallini, L, Borges, WDS, de Andrade, JP, Bastida, J & Osorio, E 2019, Amaryllidaceae Alkaloids from ...
more infohttps://pure.unibague.edu.co/es/publications/amaryllidaceae-alkaloids-from-zephyrantes-carinata-and-their-eval

Glycosides of benzodioxole-indole alkaloids from Narcissus having axi…Glycosides of benzodioxole-indole alkaloids from Narcissus having axi…

Glycosides of benzodioxole-indole alkaloids from Narcissus having axial chirality - Detail záznamu - Knihovna Akademie věd ... Klíčová slova: Amaryllidaceae * 6-Hydroxy-galanthindole * Benzodioxole-indol alkaloids. Kód oboru RIV: EE - Mikrobiologie, ... Glycosides of benzodioxole-indole alkaloids from Narcissus having axial chirality. *. 1.. 0340863 - MBU-M 2010 RIV GB eng J - ... Glycosides of benzodioxole-indole alkaloids from Narcissus having axial chirality. Phytochemistry. Roč. 71, 2-3 (2010), s. 301- ...
more infohttps://asep.lib.cas.cz/arl-cav/sk/detail-cav_un_epca-0340863-Glycosides-of-benzodioxoleindole-alkaloids-from-Narcissus-having-axial-chirality/

Analysis of Amaryllidaceae alkaloids from Zephyranthes grandiflora by GC/MS and their cholinesterase activityAnalysis of Amaryllidaceae alkaloids from Zephyranthes grandiflora by GC/MS and their cholinesterase activity

Alkaloids of Amaryllidaceae XV. The alkaloids of Nerine bowdenii W. Wats. and Crinum moorei J. D. Hook. J Am Chem Soc 82: 2620- ... Alkaloids from Leucojum vernum and antiretroviral activity of Amaryllidaceae alkaloids. Planta Med 70: 871-873. [ Links ]. ... Seven known compounds, belonging to five structural types of Amaryllidaceae alkaloids, were identified. The alkaloid extract ... are common alkaloids in family Amaryllidaceae. Both alkaloids were tested for their AChE inhibition activity, but they were ...
more infohttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400003

Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma...Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma...

Alkaloids pancratistatin and narciclasine, isolated from Amaryllidaceae, have been shown to present antitumor activity on ... Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma ... Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma ... Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma ...
more infohttp://cancerres.aacrjournals.org/content/71/8_Supplement/3261

Cloning and characterization of norbelladine synthase catalyzing the first committed reaction in Amaryllidaceae alkaloid...Cloning and characterization of norbelladine synthase catalyzing the first committed reaction in Amaryllidaceae alkaloid...

Background Amaryllidaceae alkaloids (AAs) are a large group of plant-specialized metabolites displaying an array of biological ... Amaryllidaceae alkaloid Pathogenesis related protein 10 Alkaloid biosynthesis Narcissus pseudonarcissus Norcoclaurine synthase ... Singh A, Desgagné-Penix I: Chapter 3 : Biosynthesis of Amaryllidaceae alkaloids: A biochemical outlook. In: Alkaloids: ... Influence of precursor feeding on Amaryllidaceae alkaloid accumulation. J Nat Prod. 2011;74(11):2356-61.CrossRefPubMedGoogle ...
more infohttps://rd.springer.com/article/10.1186%2Fs12870-018-1570-4

Herbal Medicines - Amaryllidaceae Alkaloids - ALPF Medical ResearchHerbal Medicines - Amaryllidaceae Alkaloids - ALPF Medical Research

Considering that narcissus are a rich source of alkaloids see Chapter 6, this volume , it is not surprising that the genus has ... Last Updated on Tue, 26 Jan 2016 , Amaryllidaceae Alkaloids Considering that narcissus are a rich source of alkaloids (see ...
more infohttps://www.alpfmedical.info/amaryllidaceae-alkaloids/herbal-medicines.html

Total Synthesis of Bioactive Natural Products | Research groups | Imperial College LondonTotal Synthesis of Bioactive Natural Products | Research groups | Imperial College London

Amaryllidaceae alkaloids. Flowering Clivia minita plant. The Amarylidaceae genus of plant has a venerable history in relation ... Lycorine is the most widespread and abundant of the Amaryllidaceae alkaloids. It is a potent emetic, exhibits anti-viral and ... Clivonine is a lycorenine-class Amaryllidaceae alkaloid which displays insect antifeedant activity. Biosynthetically it is ... Total Synthesis of the Amaryllidaceae Alkaloid Clivonine, Org.Biomol. Chem. 2011, 9, 2809-2820 [PDF‌ (558KB)]; ...
more infohttp://www.imperial.ac.uk/spivey-group/research/total-synthesis-of-bioactive-natural-products/

Cytotoxicity and acetylcholinesterase inhibitory activity of an isolated crinine alkaloid from Boophane disticha ...Cytotoxicity and acetylcholinesterase inhibitory activity of an isolated crinine alkaloid from Boophane disticha ...

Boophane disticha of the family Amaryllidaceae is used traditionally by the indigenous people of southern Africa in the ... The present study describes for the first time, the isolation of 6-hydroxycrinamine, a crinine alkaloid, from the methanol ... Cytotoxicity and acetylcholinesterase inhibitory activity of an isolated crinine alkaloid from Boophane disticha ( ... Amaryllidaceae). Adekanmi, AE; Fouché, Gerda; Steenkamp, V URI: http://www.sciencedirect.com/science/article/pii/ ...
more infohttp://researchspace.csir.co.za/dspace/handle/10204/6381

The influence of several anticancer agents on cell proliferation, differentiation and the cell cycle of murine erythroleukemia...The influence of several anticancer agents on cell proliferation, differentiation and the cell cycle of murine erythroleukemia...

Alkaloids / pharmacology. Amaryllidaceae Alkaloids*. Animals. Antibiotics, Antineoplastic / pharmacology. Antineoplastic Agents ... 0/Alkaloids; 0/Amaryllidaceae Alkaloids; 0/Antibiotics, Antineoplastic; 0/Antineoplastic Agents; 0/Harringtonines; 0/ ...
more infohttp://www.biomedsearch.com/nih/influence-several-anticancer-agents-cell/6964028.html

Molecules | Free Full-Text | Wild Argentinian Amaryllidaceae, a New Renewable Source of the Acetylcholinesterase Inhibitor...Molecules | Free Full-Text | Wild Argentinian Amaryllidaceae, a New Renewable Source of the Acetylcholinesterase Inhibitor...

... an Amaryllidaceae alkaloid, is an effective, selective, reversible, and competitive AchE inhibitor. This work was aimed at ... Alkaloid content was characterized by means of GC-MS analysis. Chloroform basic extracts from Habranthus jamesonii, Phycella ... no previous reports on alkaloid profiles and AChEIs activity of wild Argentinian Amarillydaceae species have been publisihed. ... studying the alkaloid composition of four wild Argentinian Amarillydaceae species for the first time, as well as analyzing ...
more infohttps://www.mdpi.com/1420-3049/17/11/13473

謝仁傑謝仁傑

"Synthesis of Phenanthridine Skeletal Amaryllidaceae Alkaloids". 6. Jhang, Y.-Y.; Fan-Chiang, T.-T.; Huang, J.-M.; Hsieh, J.-C. ...
more infohttp://www2.tku.edu.tw/~tscx/chinese/teachers/teacher_view.php?id=26

Current Medicinal Chemistry | Bentham ScienceCurrent Medicinal Chemistry | Bentham Science

Apoptosis-Inducing Effects of Amaryllidaceae Alkaloids Volume:23 Issue:2 Pp: 161-185. Jerald J. Nair, Johannes van Staden and ...
more infohttp://www.eurekaselect.com/node/602/current-medicinal-chemistry/issue/23/1800/2/6836

Jansa P[au] - PubMed - NCBIJansa P[au] - PubMed - NCBI

Enantioselective Synthesis of All-Carbon Quaternary Centers Structurally Related to Amaryllidaceae Alkaloids. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Jansa+P%5Bau%5D&dispmax=50

Jagtap P[au] - PubMed - NCBIJagtap P[au] - PubMed - NCBI

Enantioselective Synthesis of All-Carbon Quaternary Centers Structurally Related to Amaryllidaceae Alkaloids. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Jagtap+P%5Bau%5D&dispmax=50

Frontiers | Naturally Occurring Acetylcholinesterase Inhibitors and Their Potential Use for Alzheimers Disease Therapy |...Frontiers | Naturally Occurring Acetylcholinesterase Inhibitors and Their Potential Use for Alzheimer's Disease Therapy |...

However, several plant species producing diverse classes of alkaloids, coumarins, terpenes, and polyphenols have been assessed ... However, several plant species producing diverse classes of alkaloids, coumarins, terpenes, and polyphenols have been assessed ... consisting of an alkaloid extracted from Amaryllidaceae family (Heinrich, 2010; Murray et al., 2013). Galantamine reversibly ... Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts. Life Sci. 71, 2521-2529. doi ...
more infohttps://www.frontiersin.org/articles/10.3389/fphar.2018.01192/full

4-Methylcatechol - Wikipedia4-Methylcatechol - Wikipedia

The Amaryllidaceae Alkaloids. In.: Arnold Brossi (ed.) The Alkaloids, Chapter 3. Academic Press.. ... Members of the monocot subfamily Amaryllidoideae present a unique type of alkaloids, the norbelladine alkaloids, which are 4- ...
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Five-membered Monoheterocyclic Compounds Alkaloids (continued): Amaryllidaceae Alkaloids. Sainsbury, M., 1964, Rodds Chemistry ... The Quinoline Alkaloids. Sainsbury, M., 1964, Rodds Chemistry of Carbon Compounds: A Modern Comprehensive Treatise. 2nd ed. ... The Isoquinoline Alkaloids. Dyke, S. F., 1964, Rodds Chemistry of Carbon Compounds: A Modern Comprehensive Treatise. 2nd ed. ...
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Five-membered Monoheterocyclic Compounds Alkaloids (continued): Amaryllidaceae Alkaloids. Sainsbury, M., 1964, Rodds Chemistry ... The Quinoline Alkaloids. Sainsbury, M., 1964, Rodds Chemistry of Carbon Compounds: A Modern Comprehensive Treatise. 2nd ed. ... The Isoquinoline Alkaloids. Dyke, S. F., 1964, Rodds Chemistry of Carbon Compounds: A Modern Comprehensive Treatise. 2nd ed. ...
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Concentration-dependent effects of narciclasine on cell cycle progression in Arabidopsis root tips. | Sigma-AldrichConcentration-dependent effects of narciclasine on cell cycle progression in Arabidopsis root tips. | Sigma-Aldrich

Narciclasine (NCS) is an Amaryllidaceae alkaloid isolated from Narcissus tazetta bulbs. NCS has inhibitory effects on a broad ...
more infohttps://www.sigmaaldrich.com/catalog/papers/22204558

Scadoxus puniceus - WikipediaScadoxus puniceus - Wikipedia

Koorbanally, N. A.; Raghoo, M. & Crouch, N. R. (2006). "Amaryllidaceae alkaloids from Scadoxus puniceus" (PDF). The American ... The alkaloids in the plant include haemanthamines, haemanthidine, 6-β-hydroxycrinamine, scapunine, and scadoxucines. ...
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J. Braz. Chem. Soc. -
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Studies toward the synthesis of Amaryllidaceae alkaloids from Morita-Baylis-Hillman adducts: a straightforward synthesis of ...
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JoVE | Peer Reviewed Scientific Video Journal - Methods and ProtocolsJoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols

Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimers disease. This compound is primarily ...
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Dr. Snezna Rogelj: New Mexico TechDr. Snezna Rogelj: New Mexico Tech

5, 10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against ... A Crinine-Type Amaryllidaceae Alkaloid Exhibiting Cytostatic Activity towards Apoptosis-Resistant Glioma Cells. ChemMedChem. 7( ... 5. Discovery of a Novel Tubulin-Targeting Scaffold Derived from the Rigidin Family of Marine Alkaloids. Journal of Medicinal ... Jonquailine, a new pretazettine-type alkaloid isolated from Narcissus jonquilla quail, with activity against drug-resistant ...
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IJMS  | Free Full-Text | Whartons Jelly-Derived Mesenchymal Stem Cells:  Phenotypic Characterization and Optimizing Their ...IJMS | Free Full-Text | Wharton's Jelly-Derived Mesenchymal Stem Cells: Phenotypic Characterization and Optimizing Their ...

Towards a Molecular Understanding of the Biosynthesis of Amaryllidaceae Alkaloids in Support of Their Expanding Medical Use ...
more infohttp://mdpi.com/1422-0067/14/6/11692/htm
  • From the bulbs of Zephyranthes robusta Baker (Amaryllidaceae), seven known compounds, belonging to four structural types of Amaryllidaceae alkaloids, were identified and quantified by GC-MS. The alkaloid extract from the bulbs showed promising acetylcholinesterase and butyrylcholinesterase inhibitory activities against HuAChE (IC50 = 35.9 ± 3.5 μg/mL) and HuBuChE (IC50 = 190.9 ± 8.2 μg/mL). (cas.cz)
  • Specifically, norcoclaurine synthase (NCS) which catalyzes the condensation of dopamine and 4-hydroxyphenylacetaldehyde as the first step in benzylisoquinoline alkaloid biosynthesis. (springer.com)
  • The Amarylidaceae genus of plant has a venerable history in relation to the development of organic chemistry as the result of being the source of a wide range of highly bio-active natural products and also because speculation about the biosynthesis of various alkaloids from these plants led to the first postulation of oxidative phenolic coupling as a major mechanism of structural diversity in nature. (imperial.ac.uk)
  • To explore the mode of action of these alkaloids derivatives, we tested their capacity to inhibit protein synthesis, compared their pharmacological profile with 80 anticancer compounds on 16 tumor cell lines (oncoprofile.16) and explored their impact on major cellular functions such as cellular integrity, cell cycle, topoisomerases inhibition, DNA damage and synthesis. (aacrjournals.org)
  • The present study describes for the first time, the isolation of 6-hydroxycrinamine, a crinine alkaloid, from the methanol extract of the bulbs of Boophane disticha. (csir.co.za)
  • 11.Artem Kireev (2005): Synthesis and Comparative Biological Evaluation of Structurally Simplified Analogues of Selected Amaryllydaceae Alkaloids with Potent Anticancer and Antiviral Activities. (nmt.edu)
  • However, several plant species producing diverse classes of alkaloids, coumarins, terpenes, and polyphenols have been assessed for their anti-AChE activity, becoming potential candidates for new anti-AD drugs. (frontiersin.org)
  • Our approach to this alkaloid uses a retro -Cope elimination to establish the crucial trans -B-C ring fusion. (imperial.ac.uk)
  • 2006), as well as other alkaloids with interesting pharmacological activities: antimalarial, antiviral and antiproliferative (Campbell et al. (scielo.br)
  • Amaryllidaceae alkaloids (AAs) are a large group of plant-specialized metabolites displaying an array of biological and pharmacological properties. (springer.com)