Alkaloids derived from TYRAMINE combined with 3,4-dihydroxybenzaldehyde via a norbelladine pathway, including GALANTAMINE, lycorine and crinine. They are found in the Amaryllidaceae (LILIACEAE) plant family.
A monocot family within the order Liliales. This family is divided by some botanists into other families such as Convallariaceae, Hyacinthaceae and Amaryllidaceae. Amaryllidaceae, which have inferior ovaries, includes CRINUM; GALANTHUS; LYCORIS; and NARCISSUS and are known for AMARYLLIDACEAE ALKALOIDS.
A plant genus of the family LILIACEAE. Members contain radiatine, vittatine, haemanthamine, lycorenine, dihydrolycorine, lycorine, lycoricidinol and lycoricidine.
A plant genus of the family LILIACEAE. Members contain ungiminorine and LECTINS.
Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)
A genus of the plant family Liliaceae (sometimes classified as Alliaceae) in the order Liliales. Many produce pungent, often bacteriostatic and physiologically active compounds and are used as VEGETABLES; CONDIMENTS; and medicament, the latter in traditional medicine.
Cycloalkanes containing three or more hydroxyl groups on the ring atoms. Some polyhydroxypiperidines (PIPERIDINES) are called iminocyclitols or aza-sugars.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
A republic in western Africa, south of GUINEA and west of LIBERIA. Its capital is Freetown.
Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
A publication issued at stated, more or less regular, intervals.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).
Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.
The continuous sequential physiological and psychological maturing of an individual from birth up to but not including ADOLESCENCE.
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.
Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which VEGETABLE PROTEINS is available.
Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)
The functional hereditary units of PLANTS.
The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)
The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
Activities performed to identify concepts and aspects of published information and research reports.
Extensive collections, reputedly complete, of references and citations to books, articles, publications, etc., generally on a single subject or specialized subject area. Databases can operate through automated files, libraries, or computer disks. The concept should be differentiated from DATABASES, FACTUAL which is used for collections of data and facts apart from bibliographic references to them.
Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.
Derivatives of ethylene, a simple organic gas of biological origin with many industrial and biological use.
Compounds similar to hydrocarbons in which a tetravalent silicon atom replaces the carbon atom. They are very reactive, ignite in air, and form useful derivatives.
Organic compounds that contain silicon as an integral part of the molecule.
Organic or inorganic compounds that contain the -N3 group.
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

In vitro activities of two antimitotic compounds, pancratistatin and 7-deoxynarciclasine, against Encephalitozoon intestinalis, a microsporidium causing infections in humans. (1/54)

The antiparasitic effect of a collection of compounds with antimitotic activity has been tested on a mammalian cell line infected with Encephalitozoon intestinalis, a microsporidian causing intestinal and systemic infection in immunocompromised patients. The antiparasitic effect was evaluated by counting the number of parasitophorous vacuoles detected by immunofluorescence. Out of 526 compounds tested, 2 (pancratistatin and 7-deoxynarciclasine) inhibited the infection without affecting the host cell. The 50% inhibitory concentrations (IC(50)s) of pancratistatin and 7-deoxynarciclasine for E. intestinalis were 0.18 microM and 0.2 microM, respectively, approximately eightfold lower than the IC(50)s of these same compounds against the host cells. Electron microscopy confirmed the gradual decrease in the number of parasitophorous vacuoles and showed that of the two life cycle phases, sporogony was more sensitive to the inhibitors than merogony. Furthermore, the persistence of meronts in some cells apparently devoid of sporonts and spores indicated that the inhibitors block development rather than entry of the parasite into the host cell. The occurrence of binucleate sporoblasts and spores suggests that these inhibitors blocked a specific phase of cell division.  (+info)

Lycobetaine acts as a selective topoisomerase II beta poison and inhibits the growth of human tumour cells. (2/54)

The phenanthridine alkaloid lycobetaine is a minor constituent of Amaryllidaceae. Inhibition of cell growth was studied in the clonogenic assay on 21 human tumour xenografts (mean IC(50) = 0.8 microM). The growth of human leukaemia cell lines was also potently inhibited (mean IC(50) = 1.3 microM). Athymic nude mice, carrying s.c. implanted human gastric tumour xenograft GXF251, were treated i.p. with lycobetaine for 4 weeks, resulting in a marked tumour growth delay. Lycobetaine was found to act as a specific topoisomerase II beta poison. In the presence of calf thymus DNA, pure recombinant human topoisomerase II beta protein was selectively depleted from SDS-gels, whereas no depletion of topoisomerase II alpha protein was observed. In A431 cells immunoband-depletion of topoisomerase II beta was induced, suggesting stabilization of the covalent catalytic DNA-intermediate in living cells. It is reasonable to assume that this mechanism will cause or at least contribute significantly to the antitumour activity.  (+info)

Inhibition of cell cycle progression through specific phase by pancratistatin derivatives. (3/54)

Pancratistatin derivatives, 1-O-(3-hydroxybutyryl)pancratistatin (HBP) and 1-O-(3-O-beta-D-glucopyranosylbutyryl)pancratistatin (GBP), showed strong cytostatic activity against rat embryo fibroblast 3Y1 at concentrations less than 1 microM. When the effect on cell cycle progression was examined in 3Y1 fibroblasts arrested at G0/G1 phase by serum deprivation, HBP, GBP, and pancratistatin inhibited the progression of 3Y1 fibroblasts from G0/G1 to S phase. In addition, when the effect on cell cycle progression was studied in 3Y1 fibroblasts synchronized at late G1/early S phases by treating with hydroxyurea, HBP blocked further progression through S phase, while GBP and pancratistatin did not affect the progression, but retarded it. On the other hand, when the effect of HBP and GBP on the progression was evaluated in promyelocytic leukemia HL-60RG cells synchronized at G0/G1 phase, the cells did not progress into S phase and accumulated in sub G0/G1 phase, which indicated apoptotic cells. These findings suggest that of Amaryllidaceae alkaloids, HBP blocks the progression of cell cycle at least at G0/G1 and S phases and GBP does at least at G0/G1 phase, resulting in apoptosis induction in tumor cells.  (+info)

Isolation of the acetylcholinesterase inhibitor ungeremine from Nerine bowdenii by preparative HPLC coupled on-line to a flow assay system. (4/54)

In an attempt to isolate the active compound while detecting acetylcholinesterase inhibitory activity, we applied a fluorometric flow assay system to an on-line coupled preparative HPLC. The MeOH extract of Nerine bowdenii showed a strong inhibitory peak in the on-line assay, and the active compound was isolated by CPC and HPLC. It was identified as ungeremine by analysis of its (1)H-NMR, 2D-NMR, and NOESY spectra. The assignment of the active N. bowdenii constituent was also confirmed by co-TLC, co-HPLC, and co-(1)H-NMR experiments using an authentic sample of synthetic ungeremine. The IC(50) value of ungeremine was 0.35 microM, showing stronger activity than galanthamine (2.2 microM).  (+info)

Localization of ascorbic acid, ascorbic acid oxidase, and glutathione in roots of Cucurbita maxima L. (5/54)

To understand the function of ascorbic acid (ASC) in root development, the distribution of ASC, ASC oxidase, and glutathione (GSH) were investigated in cells and tissues of the root apex of Cucubita maxima. ASC was regularly distributed in the cytosol of almost all root cells, with the exception of quiescent centre (QC) cells. ASC also occurred at the surface of the nuclear membrane and correspondingly in the nucleoli. No ASC could be observed in vacuoles. ASC oxidase was detected by immunolocalization mainly in cell walls and vacuoles. This enzyme was particularly abundant in the QC and in differentiating vascular tissues and was absent in lateral root primordia. Administration of the ASC precursor L-galactono-gamma-lactone markedly increased ASC content in all root cells, including the QC. Root treatment with the ASC oxidized product, dehydroascorbic acid (DHA), also increased ASC content, but caused ASC accumulation only in peripheral tissues, where DHA was apparently reduced at the expense of GSH. The different pattern of distribution of ASC in different tissues and cell compartments reflects its possible role in cell metabolism and root morphogenesis.  (+info)

Effects of lycorine on HL-60 cells via arresting cell cycle and inducing apoptosis. (6/54)

As a natural anti-cancer alkaloid extracted from Amaryllidaceae, lycorine shows various biological effects on tumor cells. The survival rate of HL-60 cells exposed to lycorine was decreased in a dose-dependent manner with 1 microM as the 50% inhibitory concentration (IC50), cell growth was slowed down by arresting cell cycle at G2/M phase, and cell regeneration potential was inhibited. HL-60 cells exhibited typical apoptotic morphological changes, apoptotic DNA "ladder" pattern, and sub-G1 peak in cell phase distribution, showing apoptosis of HL-60 cells. To further understand the apoptotic molecular mechanism of lycorine on HL-60 cells, caspase activity was tested by colorimetric assay, and the expression of Bcl-2 and Bax proteins was examined by Western blotting. The increase of caspase-8, -9, -3 activities demonstrated that caspase was a key mediator of apoptotic pathways induced by lycorine. Under-expression of Bcl-2 and increase of Bax:Bcl-2 ratio showed that Bcl-2 family proteins were involved in apoptosis. Our finding suggests that lycorine can suppress leukemia growth and reduce cell survival via arresting cell cycle and inducing apoptosis of tumor cells.  (+info)

Antineoplastic agents. 553. The Texas grasshopper Brachystola magna. (7/54)

Bioassay (P388 lymphocytic leukemia cell line and human cancer cell lines) guided separation of an extract prepared from the previously chemically uninvestigated Texas grasshopper Brachystola magna led to isolation of the cancer cell growth inhibitory pancratistatin (1), narciclasine (2), and ungeremine (3). Pancratistatin (1) was first isolated from the bulbs of Hymenocallis littoralis), and the original crystal structure was deduced by X-ray analysis of a monomethyl ether derivative. In the present study pancratistatin (1) was isolated from an extract of B. magna, which led to the X-ray crystal structure of this anticancer drug. Since isoquinoline derivatives 1-3 are previously known only as constituents of amaryllidaceous plants, some of the interesting implications of their rediscovery in the grasshopper B. magna that does not appear to utilize amaryllis family plants were discussed.  (+info)

An efficient synthesis of (+/-)-Lycoricidine featuring a Stille-IMDAF cycloaddition cascade. (8/54)

[reaction: see text] A highly efficient total synthesis of (+/-)-Lycoricidine is described. The synthesis features the ready preparation of the Lycoricidine skeleton by a Stille-IMDAF cycloaddition cascade. The resulting cycloadduct is then used for the stereocontrolled installation of the other functionality present in the C-ring of the target molecule.  (+info)

Detail záznamu - Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity - Detail záznamu - Knihovna Akademie věd České republiky
TY - JOUR. T1 - Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors. AU - Cortes, Natalie. AU - Sierra, Karina. AU - Tallini, Luciana. AU - Borges, Warley de S.. AU - de Andrade, Jean Paulo. AU - Bastida, Jaume. AU - Osorio, Edison. PY - 2019/8/12. Y1 - 2019/8/12. U2 - 10.3390/proceedings2019022066. DO - 10.3390/proceedings2019022066. M3 - Artículo. VL - 22. JO - Proceedings. JF - Proceedings. SN - 2504-3900. IS - 66. ER - ...
Pancratistatin has been selected for pre-clinical development but is sparingly soluble in water. A disodium phosphate derivative has been synthesized which is water soluble and is bioequivalent thereof. The critical step in the synthesis of the phenolic phosphate was phosphorylation of 1,2,3,4-tetraacetoxy-pancratistatin with dibenzyloxy(N,N-diisopropylamido)phosphine. This pancratistatin prodrug has the structure set forth below: ##STR1##
Alkaloids pancratistatin and narciclasine, isolated from Amaryllidaceae, have been shown to present antitumor activity on preclinical models, including melanoma. Despite extensive investigations, pancratistatin or narciclasine analogues did not succeed to provide sufficient therapeutic benefit, [1] mostly hampered by poor water solubility and systemic toxicity [1]. To overcome those limitations, we developed a chemistry program aimed at improving both their physicochemical and pharmacological properties. A literature survey suggests that any structural modification of this highly oxigenated isocarbostiryl specific scaffold would lead to a loss of activity except on position 1, difficult to achieve but interesting to explore.. A series of 40 novel 1-aminopancratistatin derivatives was synthesised starting from large quantities of narciclasine extracted from Narcissus bulbs. These novel compounds exhibit an improved pharmaceutical profile facing standard solubility, plasmatic and microsomal ...
Description from Flora of China. Herbs perennial, rarely shrubby or treelike, often with bulbs, corms, rhizomes, or tubers. Leaves basal or cauline, often narrow, margin entire or spiny. Inflorescence a terminal spike, umbel, raceme, panicle, or flowers solitary. Flowers bisexual, actinomorphic or zygomorphic, usually subtended by 1 to several spathaceous involucres. Perianth segments 6, in 2 whorls, free or connate to form a short tube, with or without a corona. Stamens 6, inserted at perianth throat or at base of segments; filaments sometimes basally connate; anther dorsifixed or basifixed, mostly introrse. Ovary inferior, 3-loculed; ovules few to many per locule; placentation axile. Style slender; stigma capitate or 3-lobed. Fruit a capsule, usually loculicidal, sometimes dehiscing irregularly, rarely a berry. Seeds with endosperm.. Qian Xiao-hu, Chen Sing-chi, Hsu Yin, Hu Zhi-bi, Huang Xiu-lan & Fan Quan-jin. 1985. Amaryllidaceae. In: Pei Chien & Ting Chih-tsun, eds., Fl. Reipubl. Popularis ...
Pancratieae are a small European tribe of subfamily Amaryllidoideae (family Amaryllidaceae), consisting of two genera including the type genus, Pancratium. The placement of Pancratieae within subfamily Amaryllidoideae is shown in the following cladogram: Two genera: Pancratium Vagaria Anal. Fam. Pl.: 58. 1829. Meerow et al 2006a. Meerow A. 1995. Towards a phylogeny of the Amaryllidaceae. In P. J. Rudall, P. J. Cribb, D. F. Cutler, and C. J. Humphries [eds.], Monocotyledons: systematics and evolution, 169-179. Royal Botanic Gardens, Kew. Müller-Doblies, U.; Müller-Doblies, D. (1996). Tribes and subtribes and some species combinations in Amaryllidaceae J St Hil R Dahlgren & al. 1985. Feddes Repertorium. 107 (5-6): S.c.1-S.c.9. Meerow A. and D. A. Snijman. 1998 Amaryllidaceae. In K. Kubitzki [ed.], Families and genera of vascular plants, vol. 3, 83-110. Springer-Verlag, Berlin. Meerow, Alan W. Michael F. Fay, Charles L Guy, Qin-BaoLi, Faridah Q Zaman and Mark W. Chase. 1999 Systematics of ...
Learn more about Amaryllidaceae. Find helpful websites. Best of the Web. Collection of sites dedicated to the studies and reporting of scientific experimentation and discoveries. Gain knowledge of the latest theories and scientific experiments through journals, forums, online magazines devoted to the sciences.
Pictures of amaryllidaceae wildflowers of West USA. Stems and narrow basal leaves - allium cernuum along the Snow Pass Trail, Yellowstone National Park, Wyoming. High resolution version
Interests in the field of plant cell culture development, preferably from medicinal plants, induction of bioactive natural product biosynthesis, identification, isolation, purification. Developed radio- and enzymeimmunoassays for the quantitation of Galanthamine, an Amaryllidaceae alkaloid with potent reversible acetylcholinesterase inhibiting activity. Galanthamine HBr is commercially available as Nivalin®. Established immunoassays for quantitation of Colchicine, which is a water soluble alkaloid with cytotoxic activity, present in several species of Liliaceae. Isolated soil microorganisms capable of highly efficient regioselective demethylation at C-3 of the Colchicine structure - an important reaction toward semi-synthetical modification of the molecule, aimed to the synthesis of less toxic derivatives ...
Jez JM, Lee SG, Sherp AM (2016) The next green movement: plant biology for the environment and sustainability. Science 353, 1241-4. Kilgore M, Holland CK, Jez JM, Kutchan TM (2016) Identification of a noroxomaritidine reductase with Amaryllidaceae alkaloid biosynthesis-related activities. J Biol Chem 291, 16740-52. Lee SG, Nwumeh R, Jez JM (2016) Structure and mechanism of isopropylmalate dehydrogenase from Arabidopsis thaliana: insights on leucine and aliphatic glucosinolate biosynthesis. J Biol Chem 291, 13421-30. Herrmann J, Nathin D, Lee SG, Sun T, Jez JM (2015) Recapitulating the structural evolution of redox regulation in adenosine-5-phosphosulfate kinase from cyanobacteria to plants. J Biol Chem 290, 24705-14. Korasick DA, Jez JM, Strader LC (2015) Refining the nuclear auxin response pathway through structural biology. Curr Opin Plant Biol 27, 22-8. Cahoon RE, Lutke WK, Cameron JC, Chen S, Lee SG, Rivard RS, Rea PA, Jez JM (2015) Adaptive engineering of phytochelatin-based heavy metal ...
One of the biggest hurdles in the fight against cancer is the non‐selective nature of most current treatments. On the other hand, opioids‐refractive cancer pain is a most important unsolved problem. Consequently, the search and development of new drugs that are tumor‐killing (while non‐cytotoxic to normal cells) and/or potent analgesics are major goals in cancer research. In this context, pancratistatin and tetrodotoxin, the most prominent representatives of two different families of natural products, have been identified as highly promising leads for cancer treatment and cancer pain, respectively; in fact, they are currently at the focus of some initiatives for pharmaceutical development.. Interest in pancratistatin stems from its high level of in vitro and in vivo cell growth inhibitory activity on a wide variety of human cancer cell lines, but particularly from its mode of action that, while yet unknown, is very selective: pancratistatin does not affect normal cells in clear contrast ...
Løkfamilien (Amaryllidaceae) er en plantefamilie i ordenen Asparagales. I APG III og APG IV-systemene er familien utvidet i forhold til eldre systematikk ved at tre eldre familier Agapanthaceae, Alliaceae (løkfamilien i snever betydning) og Amaryllidaceae (narsissfamilien) er slått sammen. Artsdatabanken har valgt å kalle den utvidede Amaryllidaceae for løkfamilien, ikke narsissfamilien. Artene er for det meste flerårige urter med løk. Bladene er linjeformede, og blomstene er tvekjønnede, symmetriske og sitter i skjermer på stilken. Amaryllidoideae har oversittende blomster, mens de to andre underfamiliene har undersittende blomster. De er utbredt i de fleste landområder. Alle arter som vokser naturlig i Norge, tilhører løkslekta (Allium). Familien omfatter mange prydplanter og grønnsaker. ...
Which family the genus belongs to has been a matter of debate since its creation. In the Cronquist system, the genus was placed in a very broadly defined family Liliaceae, along with other lilioid monocots. In 1985, Dahlgren, Clifford, and Yeo placed Agapanthus in Alliaceae, close to Tulbaghia.[9] Their version of Alliaceae also included several genera that would later be transferred to Themidaceae. In 1996, following a phylogenetic analysis of DNA sequences of the gene rbcL, Themidaceae was resurrected and Agapanthus was removed from Alliaceae.[10] The authors found Agapanthus to be sister to Amaryllidaceae and transferred it to that family. This was not accepted by the Angiosperm Phylogeny Group when they published the original APG system in 1998, because the clade consisting of Agapanthus and Amaryllidaceae had only 63% bootstrap support. The APG system recognized three separate families, Agapanthaceae, Alliaceae sensu stricto, and Amaryllidaceae sensu stricto. Agapanthaceae consisted of ...
JoVE publishes peer-reviewed scientific video protocols to accelerate biological, medical, chemical and physical research. Watch our scientific video articles.
dependent on fire to flower. Like most members of the Amaryllidaceae, the seeds have a characteristic black or blue crust of the ... is the new name for two species of bulbs belonging in the Amaryllidaceae family. These plants were previously thought to be of the genus .... ...
Background: During evolution, plants and other organisms have developed a diversity of chemical defences, leading to the evolution of various groups of specialized metabolites selected for their endogenous biological function. A correlation between phylogeny and biosynthetic pathways could offer a predictive approach enabling more efficient selection of plants for the development of traditional medicine and lead discovery. However, this relationship has rarely been rigorously tested and the potential predictive power is consequently unknown ...
Nuclear DNA content (2C) is used as a new criterion to investigate nearly all species of the genus Nerine Herb. The species have the same chromosome number (2n = 2x = 22), with the exception of three
Root bulbous (in all European genera). Leaves radical.; Perianth petal-like, with 6 segments. Stamens 6, the anthers turned inwards. Ovary 3-celled, inferior or adherent to the perianth-tube. Fruit a ...
RESULTS. The analyzed parameters are summarized in Table II. Mitotic metaphases and diploid karyotypes of the species are shown in Figures 1 and 2, respectively.. All seven accessions analyzed showed a common karyotype constitutedby eight chromosome pairs of different sizes and the common karyotype formula was 4m + 10sm + 2st. In most of the taxa, the longest pair corresponded to the first metacentric pair and the shortest pair was the sixth pair (submetacentric) (Table II). The shortest chromosomes were observed in P. aff. davidii and P. lutea, while the longest chromosomes were found in P. amoena. Chromosomes of P. amoena were 30% longer than chromosomes of P. aff. davidii.. For TCL, ANOVA discriminated among taxa (F= 18.22 5, P , 0.001). Considering the CL of each chromosomal pair, all the chromosomal pairs were different among taxa (Table II). In all the assessments, with exception of the seventh and eighth chromosome pairs, P. amoena was different from each other species. In general, the ...
Two low-molecular-weight fractions of sodium hyaluronate (Na-HA), denominated Hyalastin® and Hyalectin®, were investigated as potential adjuvants for ophthalmic vehicles containing pilocarpine nitrate (PiN). Tests were also performed on an ionic complex (HA/PiB) prepared from hyaluronic acid (derived from Hyalastin®) and pilocarpine base. The performance of the vehicles under study was verified by miosis and ocular retention tests carried out on albino rabbits, against a series of reference vehicles, three of which contained a high-molecular-weight fraction of Na-HA (Healon®). The group of 14 reference and test preparations exhibited Newtonian or pseudoplastic flow characteristics and encompassed a wide range of apparent viscosities (1 to 1054 mPa s). The results indicate that the HA/PiB salt and the high-MW Na-HA can significantly increase the bioavailability of pilocarpine with respect to reference vehicles of comparable viscosity: an effect that can be reasonably attributed to ...
As the plots have emptied Matthew and I have replanted them. We have planted winter hardy varieties to feed us early in the following season. In the crop rotation beds the Solanaceae and Cucurbitaceae plants (potatoes and courgettes) have gone. They have been replaced by next years crop of Amaryllidaceae and Fabaceae plants (garlic, onions, peas and beans).. We have planted garlic Picardy Wight. Other good varieties we have grown here at the Garden include Vallelado and Early Purple Wight. We have also planted broad beans Super Aquadulce. Many visitors argue its not worth bothering with autumn sown broad beans. I disagree, it is worth it if only to have something planted in the soil. It can provide winter protection to the soil. It is also a nitrogen fixing plant and useful in crop rotations and managing soil fertility.. ...
Chase, M.W.; Reveal, J.L. & Fay, M.F. (2009), A subfamilial classification for the expanded asparagalean families Amaryllidaceae, Asparagaceae and Xanthorrhoeaceae, Botanical Journal of the Linnean Society, 161 (2): 132-136, doi:10.1111/j.1095-8339.2009.00999.x ...
Zephyranthes candida produces small daisy like flower sprouting from clumps of small bulbs. The flowers close up at night and open during the day. This makes an attractive border plant.. ...
This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.. ...
Buy Unbeaten Tracks in Japan (Dodo Press) by Professor Isabella Lucy Bird (9781406592054) from Boomerang Books, Australias Online Independent Bookstore
Allcosmeticsource.com Galanthamine Hydrobromide(Lycoris P.E.) 98%/Galanthamine HBr, 100gram/bag [257]- Galanthamine Hydrobromide(Lycoris P.E.)99%/Galanthamine HBr, 100gram/bag(N.W. 100grams) Product Name: Galanthamine Hydrobromide Original Plant: Shorttube Lycoris Appearance: White to whitish crystal powder Specification: 99%min. Synonym(s): Reminyl, Nivalin Chemical name: (4aS,6R,8aS)-6-Hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzofuro[3a,3,2-e,f][2]benzazepine hydrobromide Test Method: HPLC Molecular Formula: C17H21NO3.HBr; C17H22BrNO3 Molecular Weight: 368.27 CAS No.:1953-04-4 Packing size: 100gram/bag, 500gram/carton, or according to the
China High Purity Natural 99% Galantamine Hydrobromide, Find details about China Galantamine Hydrobromide, Lycoris Radiata Extract from High Purity Natural 99% Galantamine Hydrobromide - Shaanxi Yi An Biological Technology Co., Ltd.
He studied at the Bronx High School of Science and then at the University of New York. Dropping out after a year, aged 19, he moved to Santa Cruz, California. After living on a farm for four years he decided to resume his studies in botany and horticulture at the University of California. Initially his interest in botany was focused on trees, working for three years in the arboretum of the University. He graduated in December 1978 and continued his postgraduate study at the University of Florida, after working for two years at the Marie Selby Botanical Gardens in Sarasota, Florida, where his interest in Amaryllidaceae was stimulated. His masters thesis, in 1983, was on the taxonomy of the genus Eucharis. He continued with the same subject in his doctoral studies, producing his thesis entitled A Monograph of Eucharis and Caliphruria (Amaryllidaceae) in 1986. He then moved to the University of Floridas Fort Lauderdale Research and Education Center where he was a palm and tropical ornamental ...
Stock images and information on Naked Lady, Surprise Lily, Resurrection Lily, Magic Lily, Lu cong, Lycoris squamigera, Amaryllis hallii, Photos by Steven Foster, Steven Foster Group, Inc., Eureka Springs, Arkansas
Narcissus: Narcissus, (genus Narcissus), genus of about 40 species of bulbous, often fragrant, plants in the amaryllis family (Amaryllidaceae). The genus is native primarily to Europe and includes a number of garden ornamentals such as daffodil (or trumpet narcissus, Narcissus pseudonarcissus), jonquil (N.
Galantamin (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) se koristi za tretiranje blage do umerene Alchejmerove bolesti i raznih drugih memorijskih oštećenja, a posebno za oštećenja vaskularnog porekla. On je alkaloid koji se dobija sintetičkim putem, ili iz lukovica i cveta biljki Galanthus caucasicus, Galanthus woronowii (Amaryllidaceae) i srodnih rodova.[6] Medicinska primena je počela u Sovjetskom Savezu tokom 1950-tih. Aktivni sastojak je ekstrahovan, identifikovan, i izučavan, posebno u pogledu njegovih inhibitornih svojstava enzima acetilholinsteraza.[7][8] ...
In chronic heart failure (CHF), the heart muscle does not pump blood well enough to meet the bodys need for blood and oxygen. CHF is caused by high blood pressure, coronary artery disease, and other cardiovascular conditions. It is a common cause of death in older people. Garlic (Allium sativum, Amaryllidaceae) bulb has been shown…
INTRODUCTION. Chiles position in the international market for cut flowers has had an upward trend over the past 15 yr, but at the end of this period show signs of stagnation (Reyes and Barrera, 2009). However, Chile still has a great level of exportation of cut flowers to Netherland, USA, Japan, Argentina, among others; reaching close to US$4 million annually (Reyes and Barrera, 2009). Nevertheless, still is a weak competitor in relation with the production of traditional flowers. An economic strategy to cope with this problem is to offer species such as Phycella australis (Phil.) Ravenna, a species that is now beginning to be marketed in the Biobío Region, Chile, which due that is an endemic flower would not have any competitors abroad.. The Phycella genus (Amaryllidaceae) is endemic from Chile and Argentina, includes six different species (Arroyo-Leuenberger and Dutilh, 2008) distributed along the central zone of Chile, between Coquimbo and Biobío Regions. Phycella plants are perennial, ...
In high summer Crinums are often seen blooming in old Southern gardens. Like their cousins amaryllis, crinums are also within the Amaryllidaceae family. Blooming still In abandoned gardens they may...
Allium ursinum (Ramsons) is a species of perennial herb in the family Amaryllidaceae. It has a self-supporting growth form. It has simple, broad leaves. Flowers are visited by Myopa. It is a photoautotroph. Individuals can grow to 0.27 m.. ...
TopTropicals exotic plant encyclopedia. Plant%20profile%20-%20Species:%20Crinum%20sp.%2c%20Botanical%20Family:%20Amaryllidaceae%2c%20Plant%20common%20name:%20River%20Lily%2c%20Plant%20origin:%20Australia%2c%20tropical%20Asia%2c%20South%20Africa
Lledó Ma.D., Davis A.P., Crespo M.B., Chase M.W., Fay M.F. 2004. Phylogenetic analysis of Leucojum and Galanthus (Amaryllidaceae) based on plastid matK and nuclear ribosomal spacer (ITS) DNA sequences and morphology. Plant Syst. Evol., 246(3-4): 223-243 ...
Botanical Name : Allium bisceptrum Family: Amaryllidaceae Subfamily:Allioideae Genus: Allium Species:A. bisceptrum Kingdom: Plantae Synonyms: *Allium bisceptrum
Botanical Name : Allium scorodoprasum rotundum Family: Amaryllidaceae Subfamily: Allioideae Tribe: Allieae Genus: Allium Kingdom: Plantae Order: Asparagales
Mike, I would surely be interested in Hanranthua and Zephyranthes even if they could possibly be crossed I am growing a Hippeastrum and looking at other genera to fill in areas that could. E of interest Good luck iPhone 6 Shaund , On 22 Jul 2017, at 12:22 pm, Michael Kent ,[email protected], wrote: , , With the extreme amount of rainfall (in this area) this summer, most of my , rain lilies are blooming non-stop. Earlier today, my Habranthus robustus , (10 pot) had about 30 blooms, in various stages. , , Unfortunately, my growing space is limited. So in an area measuring about , 15 x 20, I have pots of H. robustus, H. martinezii, Cooperanthes , hortensis (Received this as a freebie when ordering bulbs - internet says , name not valid - see attached picture. It looks like H. robustus except the , petal exterior is blushed red, not pink, and the bloom is slightly , smaller.), Z. candida, Z. chlorosolen, Z. citrina, Z. grandiflora, Z. , jonesii, Z. smallii, and Z. primulina. , , Several seed ...
Previous studies have demonstrated that microinjections of the α2-AR agonist guanabenz produce dose-dependent vasodepressor responses (Lim et al., 1985). It has also been shown that the systemic vasodepressor effects of guanabenz could be blocked by local application of the α2-AR antagonist yohimbine into the gigantocelluar reticular formation (Lim et al., 1988), supporting the idea that α2-ARs in the gigantocelluar reticular formation participate in the vasodepressor actions of α2-AR agonists (Chen and Chan, 1980; Lim and Chan, 1986). The present results extend these findings to show that local application of an even more potent antihypertensive agent, clonidine, can produce dose-dependent falls in arterial pressure after the application of volumes and doses (20 nl volume, 750 pmol total dose) that are a fraction of the volumes used in many other studies. These results also show that the vasodepressor and bradycardic responses to clonidine can be completely blocked in a dose-dependent ...
Definition of Narcissus in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is Narcissus? Meaning of Narcissus as a legal term. What does Narcissus mean in law?
The orientation of the organofibrous structure plays an important role not only in the biomineralization process but also in the extracellular matrix (ECM) of articular cartilage by providing cells with biomechanical cues. Here, it is reported that a long range nanofibrous orientation can be realized by a self-assembling ionic complex between (+)-charged amphiphilic peptide block copolymers with a rigid-flexible block structure (polyalanine-PLX-polyalanine; PA-PLX-PA) and (-)-charged hyaluronic acid (HA). A biomimetic 3D culture system encapsulating chondrocytes is formed by a temperature-sensitive sol-to-gel transition of the PA-PLX-PA/HA complex aqueous solution, which provides a compatible microenvironment for the cells. The cell proliferation and biomarker expression for articular cartilage are significantly improved in the PA-PLX-PA/HA complex system relative to the PA-PLX-PA or the commercially available Matrigel systems. In particular, noticeable cell clustering is observed in the ...
A memory cell is provided with a pair of electrodes, and an active layer sandwiched between the electrodes and including a molecular system and ionic complexes distributed in the molecular system. The active layer having a high-impedance state and a low-impedance state switches from the high-impedance state to the low-impedance state when an amplitude of a writing signal exceeds a writing threshold level, to enable writing information into the memory cell. The active layer switches from the low-impedance state to the high-impedance state when an amplitude of an erasing signal having opposite polarity with respect to the writing signal exceeds an erasing threshold level, to enable erasing information from the memory cell.
name conserved] Rain-lily, fairy-lily, zephyr-lily [Greek Zephyros, west wind, and anthos, flower] Raymond O. Flagg, Gerald L. Smith & Walter S. Flory† Atamosco Adanson 1763, name rejected; Cooperia Herbert. Herbs, perennial, scapose, from bulbs. Bulbs black or brown, tunicate, ovoid or globose, sometimes with long neck. Leaves sessile, erect or recumbent, with overlapping sheathing bases; blade linear, rarely exceeding 1 cm wide, smooth. Scape hollow. Inflorescence 1-flowered (rarely 2-flowered in Z. drummondii), spathaceous, otherwise ebracteate; spathe proximally tubular. Flowers erect to declinate, actinomorphic; perianth subrotate to funnelform to salverform, connate basally into tube, 2-16 cm; tepals subequal; stamens 6, of 2 different lengths, appearing equal or subequal (anthers in 2 overlapping sets of 3) to unequal (anthers of the sets not overlapping in Z. longifolia); filaments inserted just above perianth tube, erect, diverging except when shorter than tube, long-filiform to ...
The Atlas of Florida Plants provides a source of information for the distribution of plants within the state and taxonomic information. The website also provides access to a database and images of herbarium specimens found at the University of South Florida and other herbaria.
The Atlas of Florida Plants provides a source of information for the distribution of plants within the state and taxonomic information. The website also provides access to a database and images of herbarium specimens found at the University of South Florida and other herbaria.
A good horticulture therapy exercise is the forcing of narcissus bulbs...as they awaken more than one sense! Narcissus are great because they do not require advance chilling to get the bulbs to bloom indoors. This is an activity that uses gross motor movements, has a low cost, low maintenance, and quick results. I picked up 2 boxes of paperwhite narcissus that were on the clearance table at Lowes(pictured below) and proceeded to awake the magic that is locked up inside by following the instructions written on the outside of the box ...
- Grand Primo is considered one of the oldest and best selections of narcissus. It flowers early to mid-season and is adapted to mild winters like those in zones 8 and 9. It has a most pleasing fragrance.
Englisch ⇔ Deutsch: small narcissus flies bersetzung Englisch zu Deutsch ✐ Alle bersetzungen f r das Wort small narcissus flies
Shop LBT 7 Days Power Bank, 5000 mAh, Black (7DAYSBK) at Staples. Choose from our wide selection of LBT 7 Days Power Bank, 5000 mAh, Black (7DAYSBK) and get fast & free shipping on select orders.
Species: N. albimarginatus - N. atlanticus - N. calcicola - N. cuatrecasasii - N. marvieri - N. rupicola - N. scaberulus - N. watieri. Name. Narcissus sect. Apodanthi A. Fernandes. ...
AMD gave away this booklet at their Supercomputing 06 booth. Its a marketing blurb and not a technical document, but it does cover the basics of the value proposition at a high level. I have a few copies if anyone (at Sun) is interested in taking a look.
Mårten Mickos, CEO of MySQL, recently shared his thoughts on why MySQL decided to join Sun rather than continuing towards an IPO. Interesting reading, though I suggest running it through sed /\!/\./g first. Read it here.
The Amaryllidaceae Alkaloids. In.: Arnold Brossi (ed.) The Alkaloids, Chapter 3. Academic Press.. ... Members of the monocot subfamily Amaryllidoideae present a unique type of alkaloids, the norbelladine alkaloids, which are 4- ...
... is one of a number of toxic alkaloids found in various Amaryllidaceae species such as daffodils (Narcissus). Four ... alkaloids. The Alkaloids: Chemistry and Biology. 63. pp. 87-179. doi:10.1016/S1099-4831(06)63003-4. ISBN 9780124695634. PMC ... new Amaryllidaceae alkaloids from Zephyranthes candida. Shitara N, Hirasawa Y, Hasumi S, Sasaki T, Matsumoto M, Wong CP, Kaneda ...
Nair JJ, Bastida J, Codina C, Viladomat F, van Staden J (September 2013). "Alkaloids of the South African Amaryllidaceae: a ... Amaryllidaceae isocarbostyril alkaloids and their derivatives as promising antitumor agents. Transl. Oncol. 2008, 1, 1-13. ... "Cytotoxic agents of the crinane series of amaryllidaceae alkaloids". Nat Prod Commun (Review). 7 (12): 1677-88. PMID 23413581. ... Ziska, L.; Emche, S.; Johnson, E. Alterations in the production and concentration of selected alkaloids as a function of rising ...
... is a toxic alkaloid found in various Amaryllidaceae species. Kornienko A, Evidente A (2008). "Chemistry, biology, ... "Narciclasine as well as other Amaryllidaceae Isocarbostyrils are Promising GTP-ase Targeting Agents against Brain Cancers". ...
"Approaches to the Biogenetic-type Asymmetric Synthesis of Some Amaryllidaceae Alkaloids". Heterocycles. 6 (9): 1752. doi: ... "A Biogenetic-type Asymmetric Synthesis of Optically Active Amaryllidaceae Alkaloids: (+)- and (−)-Galanthamine from L-Tyrosine ... 3-diones and Total Synthesis of Diverse Families of Sterically Congested Alkaloids". The Journal of Organic Chemistry. 73 (19 ...
... is a crinine-like alkaloid from the Amaryllidaceae plant family. "hemanthamine". MeSH Database. National Center ...
"Analysis of Amaryllidaceae alkaloids from Zephyranthes grandiflora by GC/MS and their cholinesterase activity" (PDF). Brazilian ... S. L. (Amaryllidaceae, Hippeastreae), with Notes on the Genus in Colombia" (PDF). Rev. Acad. Colomb. Cienc. 28 (107): 177-186. ... Ji Zhanhe & Alan W. Meerow (2000). "Amaryllidaceae" (PDF). Flora of China (中国植物志). Science Press & the Missouri Botanical ... It is classified under the subfamily Amaryllidoideae of the Amaryllis family (Amaryllidaceae). In broader classifications, they ...
Juliane Kirst: Synthesis of polyhalogenated carbazoles and total synthesis of amaryllidaceae alkaloids pratosine and hippadine ...
South African National Biodiversity Institute "Alkaloids of the amaryllidaceae: Brunsvigine" - Tetrahedron, Volume 31, Issue 16 ... Brunsvigia bosmaniae is a South African geophyte belonging to the family Amaryllidaceae, and occurring along the dry west coast ... Brunsvigia species are rich in alkaloids, particularly brunsvigine or 5,11b-methanomorphanthridine, and may be extremely toxic ...
A variety of alkaloids with affinity for the serotonin transporter have been isolated from Boophone disticha. Appendix: 18 ( ... "Amaryllidaceae". succulent-plant.com. Retrieved 2018-02-07. Sandager M, Nielsen ND, Stafford GI, van Staden J, Jäger AK (2005 ... Neergaard J, Andersen J, Pedersen ME, Stafford GI, van Staden J, Jäger AK (2009). "Alkaloids from Boophone disticha with ... Boophone is a small genus of herbaceous, perennial and bulbous plants in the Amaryllis family (Amaryllidaceae, subfamily ...
They say that the bulbs were boiled in lye to remove toxic alkaloids before consumption. This is the only known instance of any ... Hymenocallis pimana is a member of the genus Hymenocallis, in the family Amaryllidaceae. Common name in English is Pima spider- ... Hymenocallis pimana (Amaryllidaceae): a new species from northwestern Mexico. Phytologia 68(4):255-259. Laferrière, Joseph E., ... Native detoxification of bulbs of Mountain Pima spider-lily (Hymenocallis pimana, Amaryllidaceae). Economic Botany 52(2):207- ...
"Towards a Molecular Understanding of the Biosynthesis of Amaryllidaceae Alkaloids in Support of Their Expanding Medical Use". ... "Amaryllidaceae.org (in French). Retrieved 2 April 2014.. *. Vigneron, Pascal. "Hippeastrum: Bibliographie". Amaryllidaceae.org. ... and psychopharmacological activity due to their high alkaloid content.[28][99] One alkaloid isolated from Hippeastrum vittatum ... Vigneron 2008, Amaryllidaceae épiphytes. *^ Williams, M.; Dudley, T.R. (1984). "Chromosome Count for Hippeastrum iguazuanum". ...
John R. Lewis (2000). "Amaryllidaceae, muscarine, imidazole, oxazole, thiazole and peptide alkaloids, and other miscellaneous ... Iboga-type alkaloids[81] Ibogamine, ibogaine, voacangine[81] Aspidosperma-type alkaloids[81] Vincamine, vinca alkaloids, ... अ आ इ ई उ ऊ ए ऐ ओ औ क ख ग घ ङ च छ ज झ ञ Chemical Encyclopedia: isoquinoline alkaloids. xumuk.ru ... इन्हें भी देखें: indole alkaloids. Non-isoprene indole alkaloids Simple indole derivatives [80] Tryptophan → tryptamine or 5- ...
... approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe ... "Amaryllidaceae". Amaryllidaceae.org (in French). Retrieved 23 October 2014.. *. Glanfield, Emma (25 January 2015). "Bulbs go ... Meerow, A. W.; Fay, M.F.; Guy, C.L.; Li, Q.-B.; Zaman, F.Q.; Chase, M.W. (1999). "Systematics of Amaryllidaceae based on ... Traub, H.P. (1963). Genera of the Amaryllidaceae. La Jolla, California: American Plant Life Society. Archived from the original ...
... alkaloids. The Alkaloids: Chemistry and Biology. 63. pp. 87-179. doi:10.1016/S1099-4831(06)63003-4. ISBN 9780124695634. PMC ... Herbert, William (1837a). Amaryllidaceae: Preceded by an Attempt to Arrange the Monocotyledonous Orders, and Followed by a ... The eventual position of Narcissus within the Amaryllidaceae family only became settled in the twenty-first century with the ... The genus Narcissus belongs to the Narcisseae tribe, one of 13 within the Amaryllidoideae subfamily of the Amaryllidaceae. It ...
John R. Lewis (2000). "Amaryllidaceae, muscarine, imidazole, oxazole, thiazole and peptide alkaloids, and other miscellaneous ... a b c d e f g h i j k l m n o p q r s t Chemical Encyclopedia: isoquinoline alkaloids. xumuk.ru ... Iboga-type alkaloids[125] Ibogamine, ibogaine, voacangine[125] Aspidosperma-type alkaloids[125] Vincamine, vinca alkaloids,[26] ... a b c d Chemical Encyclopedia: alkaloids. xumuk.ru *^ Roberts, M. F. (Margaret F.) (1998). Alkaloids : Biochemistry, Ecology, ...
On je alkaloid koji se dobija sintetičkim putem, ili iz lukovica i cveta biljki Galanthus caucasicus, Galanthus woronowii ( ... Amaryllidaceae) i srodnih rodova.[6] Medicinska primena je počela u Sovjetskom Savezu tokom 1950-tih. Aktivni sastojak je ... Mashkovsky, MD; Kruglikova-Lvova, RP (1951). "On the pharmacology of the new alkaloid galantamine". Farmakologia Toxicologia 14 ...
Willaman, John James; Schubert, Bernice (1961). Alkaloid-bearing Plants and Their Contained Alkaloids. U.S. Department of ... Ismene amancaes, commonly called amancae or amancay, is a herbaceous plant species in the family Amaryllidaceae and native to ... It is reported that I. amancaes contains the alkaloid substances galantamine and narcissidine. Remains of I. amancaes have been ... Glasby, John (2012). Encyclopedia of the Alkaloids: Volume 2 (I-Z). Springer Science & Business Media. p. 988. ISBN ...
5. 2013). „Towards a Molecular Understanding of the Biosynthesis of Amaryllidaceae Alkaloids in Support of Their Expanding ... 5. 2013). „Towards a Molecular Understanding of the Biosynthesis of Amaryllidaceae Alkaloids in Support of Their Expanding ... Chemical and biological aspects of "Narcissus" alkaloids. The Alkaloids: Chemistry and Biology. 63. Amsterdam: Elsevier Inc. ... 9. 2012). „Alkaloids from Narcissus serotinus". Journal of Natural Products. 75 (9): 1643-1647. PMID 22917000. doi:10.1021/ ...
John James Willaman and Bernice Schubert Alkaloid-bearing Plants and Their Contained Alkaloids (August 1961), p. 94, at Google ... Dönmez, Emel Oybak; Işik, Serap (2008). "Pollen morphology of Turkish Amaryllidaceae, Ixioliriaceae and Iridaceae". Grana. 47 ( ... It has a chromosome count: 2n=20, and has an unnamed alkaloid (as of 1961), contained within its rhizome. A study in 2014, was ...
... is a flowering plant in the Amaryllidaceae family. It is a bulbous plant from South Africa (east Cape ... The genus Scadoxus is known to have some strongly toxic species, containing poisonous alkaloids. These are lethal to animals, ... "Generic relationships among the baccate-fruited Amaryllidaceae (tribe Haemantheae) inferred from plastid and nuclear non-coding ...
Fritillaria in particular contains steroidal alkaloids of the cevanine and solanum type. Solanidine and solanthrene alkaloids ... Cronquist merged the Liliaceae with the Amaryllidaceae, making this one of the largest monocotyledon families. Many other ... Li, H. J.; Jiang Y; Li P. (October 2006). "Chemistry, bioactivity and geographical diversity of steroidal alkaloids from the ... Most Fritillaria (e.g. Fritillaria imperialis, Fritillaria meleagris) bulbs contain poisonous neurotoxic alkaloids such as ...
... alkaloids. The Alkaloids: Chemistry and Biology. 63. pp. 87-179. doi:10.1016/S1099-4831(06)63003-4. ISBN 9780124695634. PMC ... Amaryllidaceae)". Plant Systematics and Evolution. 275 (1-2): 109-132. doi:10.1007/s00606-008-0015-1. Cultural China. " ...
B. disticha is a member of the daffodil family Amaryllidaceae and has also been used in preparations employed as arrow poisons ... The plant is rich in alkaloids, some of which display an action similar to that of scopolamine.[17] ...
Twelve alkaloids were identified in H. reticulatum: eight known alkaloids by GC-MS and four unknown (6α-hydroxymaritidine, 6β- ... The aim of this work was to perform the first detailed study of the alkaloid constituents of Hippeastrum reticulatum ( ... Amaryllidaceae) and to determine the anti-parasitological and cholinesterase (AChE and BuChE) inhibitory activities of the ... The Amaryllidaceae family has proven to be a rich source of active compounds, which are characterized by unique skeleton ...
Alkaloids of Amaryllidaceae XV. The alkaloids of Nerine bowdenii W. Wats. and Crinum moorei J. D. Hook. J Am Chem Soc 82: 2620- ... Alkaloids from Leucojum vernum and antiretroviral activity of Amaryllidaceae alkaloids. Planta Med 70: 871-873. [ Links ]. ... Seven known compounds, belonging to five structural types of Amaryllidaceae alkaloids, were identified. The alkaloid extract ... are common alkaloids in family Amaryllidaceae. Both alkaloids were tested for their AChE inhibition activity, but they were ...
... an Amaryllidaceae alkaloid, is an effective, selective, reversible, and competitive AchE inhibitor. This work was aimed at ... Alkaloid content was characterized by means of GC-MS analysis. Chloroform basic extracts from Habranthus jamesonii, Phycella ... no previous reports on alkaloid profiles and AChEIs activity of wild Argentinian Amarillydaceae species have been publisihed. ... studying the alkaloid composition of four wild Argentinian Amarillydaceae species for the first time, as well as analyzing ...
Alkaloids pancratistatin and narciclasine, isolated from Amaryllidaceae, have been shown to present antitumor activity on ... Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma ... Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma ... Abstract 3261: Novel hemisynthetic derivatives of Amaryllidaceae alkaloids exert antitumor activity on xenograft melanoma ...
Boophane disticha of the family Amaryllidaceae is used traditionally by the indigenous people of southern Africa in the ... The present study describes for the first time, the isolation of 6-hydroxycrinamine, a crinine alkaloid, from the methanol ... Cytotoxicity and acetylcholinesterase inhibitory activity of an isolated crinine alkaloid from Boophane disticha ( ... Amaryllidaceae). Adekanmi, AE; Fouché, Gerda; Steenkamp, V URI: http://www.sciencedirect.com/science/article/pii/ ...
Background Amaryllidaceae alkaloids (AAs) are a large group of plant-specialized metabolites displaying an array of biological ... Amaryllidaceae alkaloid Pathogenesis related protein 10 Alkaloid biosynthesis Narcissus pseudonarcissus Norcoclaurine synthase ... Singh A, Desgagné-Penix I: Chapter 3 : Biosynthesis of Amaryllidaceae alkaloids: A biochemical outlook. In: Alkaloids: ... Influence of precursor feeding on Amaryllidaceae alkaloid accumulation. J Nat Prod. 2011;74(11):2356-61.CrossRefPubMedGoogle ...
The Amaryllidaceae Alkaloids. In.: Arnold Brossi (ed.) The Alkaloids, Chapter 3. Academic Press.. ... Members of the monocot subfamily Amaryllidoideae present a unique type of alkaloids, the norbelladine alkaloids, which are 4- ...
Considering that narcissus are a rich source of alkaloids see Chapter 6, this volume , it is not surprising that the genus has ... Last Updated on Tue, 26 Jan 2016 , Amaryllidaceae Alkaloids Considering that narcissus are a rich source of alkaloids (see ...
Homolycorine is one of a number of toxic alkaloids found in various Amaryllidaceae species such as daffodils (Narcissus). Four ... alkaloids. The Alkaloids: Chemistry and Biology. 63. pp. 87-179. doi:10.1016/S1099-4831(06)63003-4. ISBN 9780124695634. PMC ... new Amaryllidaceae alkaloids from Zephyranthes candida. Shitara N, Hirasawa Y, Hasumi S, Sasaki T, Matsumoto M, Wong CP, Kaneda ...
Amaryllidaceae alkaloids. Flowering Clivia minita plant. The Amarylidaceae genus of plant has a venerable history in relation ... Lycorine is the most widespread and abundant of the Amaryllidaceae alkaloids. It is a potent emetic, exhibits anti-viral and ... Clivonine is a lycorenine-class Amaryllidaceae alkaloid which displays insect antifeedant activity. Biosynthetically it is ... Total Synthesis of the Amaryllidaceae Alkaloid Clivonine, Org.Biomol. Chem. 2011, 9, 2809-2820 [PDF‌ (558KB)]; ...
In this context, the Amaryllidaceae alkaloids have attracted considerable attention in view of their unique structural features ... None of the alkaloids isolated from; C. amabile; gave better results than the reference drugs, so it was possible to conclude ... In this study, twenty-three alkaloids were identified from; Crinum amabile; by GC-MS and two new structures (augustine; N; - ... Anti-parasitic and cholinesterase (AChE and BuChE) inhibitory activities of six alkaloids isolated from this species, including ...
Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity - Detail záznamu - ... belonging to four structural types of Amaryllidaceae alkaloids, were identified and quantified by GC-MS. The alkaloid extract ... Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity. *. 1.. 0346356 - ... Analysis of Amaryllidaceae Alkaloids from Zephyranthes robusta by GC-MS and Their Cholinesterase Activity. Natural Product ...
Analysis of galanthamine-type alkaloids by capillary gas chromatography-mass spectrometry in plants Publication Type:. Journal ... Home » Literature » Analysis of galanthamine-type alkaloids by capillary gas chromatography-mass spectrometry in plants ...
Hippeastrum reticulatum (Amaryllidaceae): alkaloid profiling, biological activities and molecular docking. Molecules, 22 (12). ... Twelve alkaloids were identified in H. reticulatum: eight known alkaloids by GC-MS and four unknown (6α-hydroxymaritidine, 6β- ... The Amaryllidaceae family has proven to be a rich source of active compounds, which are characterized by unique skeleton ... The aim of this work was to perform the first detailed study of the alkaloid constituents of Hippeastrum reticulatum ( ...
Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors. En: ... Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors. / Cortes ... Amaryllidaceae Alkaloids from Zephyrantes Carinata and Their Evaluation as Cholinesterases (AChE and BChE) Inhibitors. ... Cortes, N, Sierra, K, Tallini, L, Borges, WDS, de Andrade, JP, Bastida, J & Osorio, E 2019, Amaryllidaceae Alkaloids from ...
The discovery of CYP96T1 is of special interest because it catalyzes the first major branch in Amaryllidaceae alkaloid ... The discovery of CYP96T1 is of special interest because it catalyzes the first major branch in Amaryllidaceae alkaloid ... Central to the biosynthesis of the majority of these alkaloids is a C-C phenol-coupling reaction that can have para-para, para ... Central to the biosynthesis of the majority of these alkaloids is a C-C phenol-coupling reaction that can have para-para, para ...
Alkaloids / pharmacology. Amaryllidaceae Alkaloids*. Animals. Antibiotics, Antineoplastic / pharmacology. Antineoplastic Agents ... 0/Alkaloids; 0/Amaryllidaceae Alkaloids; 0/Antibiotics, Antineoplastic; 0/Antineoplastic Agents; 0/Harringtonines; 0/ ...
Learn more about Amaryllidaceae. Find helpful websites. Best of the Web. Collection of sites dedicated to the studies and ... Antimalarial Activity Screening of Some Alkaloids and the Plant Extracts from Amaryllidaceae Abstract of the article by B. ... Total Synthesis of Montanine-Type Amaryllidaceae Alkaloids [PDF] Article by C.K. Sha and others. ... Top / Science / Biology / Plants and Animals / Plantae / Magnoliophyta / Liliopsida / Amaryllidaceae * Absolute Astronomy: ...
3. Cytotoxic Alkaloid Constituents of the Amaryllidaceae. 4. Bioactivity and Synthesis of Diarylheptanoids from Alpinia ...
Enantioselective Synthesis of All-Carbon Quaternary Centers Structurally Related to Amaryllidaceae Alkaloids. ...
This new edition contains chapters on cytotoxic phenanthridone alkaloid constituents of the Amaryllidaceae; naphthoquinone- ... phenanthridone alkaloids). The fourth part, containing investigative information on almost 300 individual plant species with ...
However, several plant species producing diverse classes of alkaloids, coumarins, terpenes, and polyphenols have been assessed ... However, several plant species producing diverse classes of alkaloids, coumarins, terpenes, and polyphenols have been assessed ... consisting of an alkaloid extracted from Amaryllidaceae family (Heinrich, 2010; Murray et al., 2013). Galantamine reversibly ... Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts. Life Sci. 71, 2521-2529. doi ...
"Synthesis of Phenanthridine Skeletal Amaryllidaceae Alkaloids". 6. Jhang, Y.-Y.; Fan-Chiang, T.-T.; Huang, J.-M.; Hsieh, J.-C. ...
Synthetic studies on Amaryllidaceae and other terrestrially derived alkaloids. Citation. Banwell, M, Gao, Y, Schwartz, B et al ... Synthetic studies on Amaryllidaceae and other terrestrially derived alkaloids, Topics in Current Chemistry, vol. 309, pp. 163- ...
Cytotoxic and Genotoxic Activities of Alkaloids from the Bulbs of Griffinia gardneriana and Habranthus itaobinus ( ... Amaryllidaceae) , 19(5): 707 - 717. Eduardo R. Cole, Jean P. de Andrade, João F. Allochio Filho, Elisângela F. P. Schmitt, ... Cytotoxic and Genotoxic Activities of Alkaloids from the Bulbs of Griffinia gardneriana and Habranthus itaobinus ( ...
Daphniphyllum Alkaloids, Daphnilactone A. Pyrrolizidine Alkaloids. Amaryllidaceae Alkaloids. Morphine. Indole Alkaloids. ... COMPARATIVE DESIGN: CLASSICS IN ALKALOID SYNTHESIS. Introduction. Lycopodium Alkaloids. ...
Apoptosis-Inducing Effects of Amaryllidaceae Alkaloids Volume:23 Issue:2 Pp: 161-185. Jerald J. Nair, Johannes van Staden and ...
Apoptosis-Inducing Effects of Amaryllidaceae Alkaloids. Current Medicinal Chemistry. * Poly(ADP-Ribose) Polymerase Inhibitors: ...
Narciclasine (NCS) is an Amaryllidaceae alkaloid isolated from Narcissus tazetta bulbs. NCS has inhibitory effects on a broad ...
Studies toward the synthesis of Amaryllidaceae alkaloids from Morita-Baylis-Hillman adducts: a straightforward synthesis of ...
  • Considering that narcissus are a rich source of alkaloids (see Chapter 6, this volume), it is not surprising that the genus has figured in herbal medicine . (alpfmedical.info)
  • Homolycorine is one of a number of toxic alkaloids found in various Amaryllidaceae species such as daffodils (Narcissus). (wikipedia.org)
  • Chemical and biological aspects of "Narcissus" alkaloids. (wikipedia.org)
  • The Amaryllidaceae alkaloids are produced by species of Amaryllidaceae including Narcissus spp. (frontiersin.org)
  • Narciclasine (NCS) is an Amaryllidaceae alkaloid isolated from Narcissus tazetta bulbs. (sigmaaldrich.com)
  • Glycosides of benzodioxole-indole alkaloid 6-hydroxy-galanthindole having axial chirality were isolated from Narcissus. (cas.cz)
  • Galanthamine is one of the toxins produced by several plants from family Amaryllidaceae, such as snowdrop (Galanthus nivalis) and daffodils (Narcissus poeticus). (ku.dk)
  • Lycorine is the most widespread and abundant of the Amaryllidaceae alkaloids. (imperial.ac.uk)
  • The Barbados Lily belongs to the Amaryllidaceae family and is toxic due to lycorine and other alkaloids. (embracepetinsurance.com)
  • Lycorine, a major alkaloid found in many Amaryllidaceae species, has been shown to have FIGURE 1 - Chemical structure of lycorine. (bvsalud.org)
  • Amaryllidaceae, along with the well-known alkaloids lycosinine B and lycorine. (bvsalud.org)
  • Lycorine hydrochloride is a natural alkaloid extracted from the Amaryllidaceae plant family, it is also an HCV inhibitor with strong activity. (abmole.com)
  • Amaryllidaceae are known as ornamental plants, furthermore some species of this family contain galanthamine, an acetylcholinesterase inhibitor approved for the treatment of Alzheimer's disease, and other alkaloids with interesting pharmacological activity. (scielo.br)
  • This work was aimed at studying the alkaloid composition of four wild Argentinian Amarillydaceae species for the first time, as well as analyzing their inhibitory activity on acetylcholinesterase. (mdpi.com)
  • To our knowledge, no previous reports on alkaloid profiles and AChEIs activity of wild Argentinian Amarillydaceae species have been publisihed. (mdpi.com)
  • Anti-parasitic and cholinesterase (AChE and BuChE) inhibitory activities of six alkaloids isolated from this species, including the two new compounds, are described herein. (unibas.ch)
  • However, several plant species producing diverse classes of alkaloids, coumarins, terpenes, and polyphenols have been assessed for their anti-AChE activity, becoming potential candidates for new anti-AD drugs. (frontiersin.org)
  • Established immunoassays for quantitation of Colchicine, which is a water soluble alkaloid with cytotoxic activity, present in several species of Liliaceae . (rutgers.edu)
  • Greek gála "milk", ánthos "flower") is a small genus of approximately 20 species of bulbous perennial herbaceous plants in the family Amaryllidaceae . (wikipedia.org)
  • Larger in stature than most other species of Amaryllidaceae, most crinums are suitable as landscape plants in or near water features while most of the smaller species can be successfully cultivated even in a small garden. (toptropicals.com)
  • 2004). Since the alkaloids are highly toxic, use of Crinum species is not recommended for the novice, as a large dose could easily be fatal. (toptropicals.com)
  • Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. (medchemexpress.com)
  • A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. (harvard.edu)
  • ChemInform Abstract: Oxidative Friedel,Crafts Reaction and Its Application to the Total Syntheses of Amaryllidaceae Alkaloids. (academicconcepts.net)
  • Specifically, norcoclaurine synthase (NCS) which catalyzes the condensation of dopamine and 4-hydroxyphenylacetaldehyde as the first step in benzylisoquinoline alkaloid biosynthesis. (springer.com)
  • The Amarylidaceae genus of plant has a venerable history in relation to the development of organic chemistry as the result of being the source of a wide range of highly bio-active natural products and also because speculation about the biosynthesis of various alkaloids from these plants led to the first postulation of oxidative phenolic coupling as a major mechanism of structural diversity in nature. (imperial.ac.uk)
  • Central to the biosynthesis of the majority of these alkaloids is a C-C phenol-coupling reaction that can have para-para', para-ortho' , or ortho-para' regiospecificity. (frontiersin.org)
  • The discovery of CYP96T1 is of special interest because it catalyzes the first major branch in Amaryllidaceae alkaloid biosynthesis. (frontiersin.org)
  • The limited supply of some Amaryllidaceae alkaloids and diversity of biological activities make the biosynthesis of Amaryllidaceae alkaloids a topic of interest for biotechnology. (frontiersin.org)
  • Kilgore M, Holland CK, Jez JM, Kutchan TM (2016) Identification of a noroxomaritidine reductase with Amaryllidaceae alkaloid biosynthesis-related activities. (wustl.edu)
  • The aim of this work was to perform the first detailed study of the alkaloid constituents of Hippeastrum reticulatum (Amaryllidaceae) and to determine the anti-parasitological and cholinesterase (AChE and BuChE) inhibitory activities of the epimers (6α-hydroxymaritidine and 6β-hydroxymaritidine). (mdpi.com)
  • Described herein is the chemoenzymatic total synthesis of several Amaryllidaceae constituents and their unnatural C-I analogues. (brocku.ca)
  • Isolation, Synthesis, and Semisynthesis of Amaryllidaceae Constituents fromNarcissusandGalanthussp. (mcmaster.ca)
  • The present study describes for the first time, the isolation of 6-hydroxycrinamine, a crinine alkaloid, from the methanol extract of the bulbs of Boophane disticha. (csir.co.za)
  • From the bulbs of Zephyranthes robusta Baker (Amaryllidaceae), seven known compounds, belonging to four structural types of Amaryllidaceae alkaloids, were identified and quantified by GC-MS. The alkaloid extract from the bulbs showed promising acetylcholinesterase and butyrylcholinesterase inhibitory activities against HuAChE (IC50 = 35.9 ± 3.5 μg/mL) and HuBuChE (IC50 = 190.9 ± 8.2 μg/mL). (cas.cz)
  • Galanthamine is an alkaloid found in the bulbs of snowdrops and several Amaryllidaceae plants. (strath.ac.uk)
  • Cytotoxic and antimalarial amaryllidaceae alkaloids from the bulbs of Lycoris radiata. (europills365.com)
  • Hippeastrum is a genus in the family Amaryllidaceae ( subfamily Amaryllidoideae , tribe Hippeastreae , and subtribe Hippeastrineae ). (wikipedia.org)
  • Wagner J, Pham HL, Doepke W (1996) Alkaloids from Hippeastrum equestre Herb. (springer.com)
  • These include several total syntheses of morphine alkaloids, total synthesis of Amaryllidaceae alkaloids and their medicinally useful derivatives, and approaches to other, highly oxygenated compounds such as xylosmin, tetrodotoxin, and idesolide. (msvu.ca)
  • This thesis describes the chemoenzymatic synthesis of three morphine alkaloids. (brocku.ca)
  • The present studies describe, as a primary goal, our recent progess toward the synthesis of morphine alkaloids from aromatic precursors. (brocku.ca)
  • Phytochemical analysis yielded more than 150 different isoquinoline or Amaryllidaceae alkaloids and some of the most noted effects are analgesic, anticholinergic, antitumour and antiviral. (toptropicals.com)
  • A Russian pharmacologist first isolated the plant alkaloid galantamine from Galanthus woronowii in the early 1950s and characterized its reversible physiological effects on muscle as an acetylcholinesterase inhibitor. (naturalproductsinsider.com)
  • While the first patented synthetic pathway for galantamine was developed in 1996-two years after the passage of the U.S. Dietary Supplement Health and Education Act of 1994 (DSHEA)-the alkaloid was being isolated from the snowdrop ( Galanthus spp. (naturalproductsinsider.com)
  • Alkaloid profiling of Galanthus woronowii Losinsk. (ege.edu.tr)
  • The Amaryllidaceae family has proven to be a rich source of active compounds, which are characterized by unique skeleton arrangements and a broad spectrum of biological activities. (mdpi.com)
  • was analyzed by GC/MS. Seven known compounds, belonging to five structural types of Amaryllidaceae alkaloids, were identified. (scielo.br)
  • To explore the mode of action of these alkaloids derivatives, we tested their capacity to inhibit protein synthesis, compared their pharmacological profile with 80 anticancer compounds on 16 tumor cell lines (oncoprofile.16) and explored their impact on major cellular functions such as cellular integrity, cell cycle, topoisomerases inhibition, DNA damage and synthesis. (aacrjournals.org)
  • Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms. (wikipedia.org)
  • [3] Some synthetic compounds of similar structure may also be termed alkaloids. (wikipedia.org)
  • The boundary between alkaloids and other nitrogen-containing natural compounds is not clear-cut. (wikipedia.org)
  • [16] Compounds like amino acid peptides , proteins , nucleotides , nucleic acid , amines , and antibiotics are usually not called alkaloids. (wikipedia.org)
  • [2] Natural compounds containing nitrogen in the exocyclic position ( mescaline , serotonin , dopamine , etc.) are usually classified as amines rather than as alkaloids. (wikipedia.org)
  • 2] Natural compounds containing nitrogen in the exocyclic position (mescaline, serotonin, dopamine, etc.) are usually attributed to amines rather than alkaloids. (scribd.com)
  • 2011). In addition to evaluating the antimicrobial compounds such as Amaryllidaceae alkaloids, which activity, it is also important to investigate the effects of are used in the drug industry. (bvsalud.org)
  • 11.Artem Kireev (2005): Synthesis and Comparative Biological Evaluation of Structurally Simplified Analogues of Selected Amaryllydaceae Alkaloids with Potent Anticancer and Antiviral Activities. (nmt.edu)
  • Six new monoterpenoid indole alkaloids from the aerial part of Gelsemium elegans . (jnu.edu.cn)
  • AbstractZ-Vallesiachotamine is a monoterpene indole alkaloid that has a β-N-acrylate group in its structure. (bvsalud.org)
  • Abdel-Halim OB, Morikawa T, Ando S, Matsuda H, Yoshikawa M (2004) New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense . (springer.com)
  • Amarallidacae alkaloids are widely present in the plant kingdom and have important biological properties such as acetylcholinesterase inhibitory activity, cytotoxicity, antitumoral activity and so on [ 19 ]. (biomedcentral.com)
  • Two new alkaloids from Crinum asiaticum var. (springer.com)
  • Ochi M, Otsuki H, Nagano K (1976) The structure of hamayne, a new alkaloid from Crinum asiaticum L. var. (springer.com)
  • Crinum is a fascinating genus of the large and equally captivating Amaryllidaceae family. (toptropicals.com)
  • 2006), as well as other alkaloids with interesting pharmacological activities: antimalarial, antiviral and antiproliferative (Campbell et al. (scielo.br)
  • Extracts from plants containing toxic alkaloids, such as aconitine and tubocurarine , were used since antiquity for poisoning arrows. (wikipedia.org)
  • Gorer & J.H.Harvey, S. candida extracts and alkaloids of S. clusiana , S. lutea and the B. Mathew & T. Baytop (endemic to Turkey), and S. anti-acetylcholinesterase and antioxidant activities of clusiana (Ker Gawl. (bvsalud.org)
  • Alkaloids pancratistatin and narciclasine, isolated from Amaryllidaceae, have been shown to present antitumor activity on preclinical models, including melanoma. (aacrjournals.org)
  • Specific examples of alkaloids derived from (10b R ,4a S )-noroxomaritidine include haemanthamine, maritidine, vittatine, and pretazettine. (frontiersin.org)
  • The alkaloids of the Amaryllidaceae : the isolation and structures of two new alkaloids from Haemanthus natalensis and Nerine krigeii and contributions to the chemistry of coccinine : the absolute configuration of alkaloids based on the 5:10b-Ethanpohenanthridine nucleus. (ukzn.ac.za)
  • The alkaloids of the Amaryllidaceae : the isolation of the alkaloids of Boophone disticha Herb. (ukzn.ac.za)
  • Plants of the Amaryllidaceae family are well-known for their ornamental value but also for the alkaloids they produce. (scielo.br)
  • Alkaloids are produced by a large variety of organisms including bacteria , fungi , plants , and animals . (wikipedia.org)
  • Alkaloid-containing plants have been used by humans since ancient times for therapeutic and recreational purposes. (wikipedia.org)
  • Developed radio- and enzymeimmunoassays for the quantitation of Galanthamine , an Amaryllidaceae alkaloid with potent reversible acetylcholinesterase inhibiting activity. (rutgers.edu)
  • Amaryllidaceae alkaloids (AAs) are a large group of plant-specialized metabolites displaying an array of biological and pharmacological properties. (springer.com)
  • The third part of the book comprises six chapters dedicated to either plant chemotherapeutical approaches to specific cancer types (e.g. bladder, prostate) or specific groups of plant secondary metabolites with novel and promising properties for cancer treatment (e.g. naphthoquinones, lectins, phenanthridone alkaloids). (routledge.com)
  • The present article reviews the potential efficacy of plant-derived alkaloids, which possess potential therapeutic effects against several NDDs including Alzheimer's disease (AD), Huntington disease (HD), Parkinson's disease (PD), Epilepsy, Schizophrenia, and stroke. (ijbs.com)
  • strychnine is obtained from the seed of the Strychnine tree ( Strychnos nux-vomica L.). [5] Where several alkaloids are extracted from one plant their names are often distinguished by variations in the suffix: "idine", "anine", "aline", "inine" etc. (wikipedia.org)
  • Strychnos nux-vomica L.).[5] If several alkaloids are extracted from one plant then their names often contain suffixes 'idine', 'anine', 'aline', 'inine' etc. (scribd.com)
  • In this context, the Amaryllidaceae alkaloids have attracted considerable attention in view of their unique structural features and various biological activities. (unibas.ch)
  • Alkaloids from all major structural classes of Amaryllidaceae alkaloids have biological activities. (frontiersin.org)
  • Alkaloids constitute positive roles in ameliorating pathophysiology of these illnesses by functioning as muscarinic and adenosine receptors agonists, anti-oxidant, anti-amyloid and MAO inhibitors, acetylcholinestrase and butyrylcholinesterase inhibitor, inhibitor of α-synuclein aggregation, dopaminergic and nicotine agonist, and NMDA antagonist. (ijbs.com)
  • Alkaloids can be toxic too ( e.g. atropine , tubocurarine ). (wikipedia.org)
  • The Amaryllidaceae family is well known for its pharmacologically active alkaloids. (mdpi.com)
  • Boophane disticha of the family Amaryllidaceae is used traditionally by the indigenous people of southern Africa in the treatment of several neurological disorders. (csir.co.za)
  • Galantamine, or galanthamine as it was originally termed, is an alkaloid constituent contained in multiple members of the Amaryllidaceae family. (naturalproductsinsider.com)
  • 9-O-demethyllycosinine B is the third lycosinine variant identified in the Amaryllidaceae family. (bvsalud.org)
  • The toxin belongs to the Amaryllidaceae family of alkaloids, acting as an acetylcholinesterase inhibitor (AChEI). (ku.dk)
  • Members of the monocot subfamily Amaryllidoideae present a unique type of alkaloids, the norbelladine alkaloids, which are 4-methylcatechol derivatives combined with tyrosine. (wikipedia.org)
  • DeAngelis GG, Wildman WC (1969) Identification of Amaryllidaceae alkaloids utilizing ORD and CD spectroscopy. (springer.com)
  • Analogues of Marine Guanidine Alkaloids are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania ( L .) infantum Intracellular Amastigotes" Martins, L. F. et al. (uci.edu)
  • The chemical structures of these alkaloids are very variable as well as their pharmacological properties. (scielo.br)
  • Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimer's disease. (jove.com)
  • Galanthamine, is the most known Amaryllidaceae alkaloid, which is currently being prescribed for the treatment of mild to moderate Alzheimer's disease (AD) due to its anti-acetylcholinesterase activity. (usda.gov)
  • Clivonine is a lycorenine-class Amaryllidaceae alkaloid which displays insect antifeedant activity. (imperial.ac.uk)
  • Study of biological activity of isolated alkaloids from Argemone grandiflora (Papaveraceae)II. (cuni.cz)
  • The chemical investigation of the Amaryllidaceae and Hyacinthaceae. (ukzn.ac.za)