Alveolitis, Extrinsic Allergic: A common interstitial lung disease caused by hypersensitivity reactions of PULMONARY ALVEOLI after inhalation of and sensitization to environmental antigens of microbial, animal, or chemical sources. The disease is characterized by lymphocytic alveolitis and granulomatous pneumonitis.Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.Bird Fancier's Lung: A form of alveolitis or pneumonitis due to an acquired hypersensitivity to inhaled avian antigens, usually proteins in the dust of bird feathers and droppings.Bronchoalveolar Lavage Fluid: Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.Pulmonary Alveoli: Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.Bronchoalveolar Lavage: Washing out of the lungs with saline or mucolytic agents for diagnostic or therapeutic purposes. It is very useful in the diagnosis of diffuse pulmonary infiltrates in immunosuppressed patients.Farnesol: A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Lung: Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.Sarcoidosis, Pulmonary: Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)Dry Socket: A condition sometimes occurring after tooth extraction, particularly after traumatic extraction, resulting in a dry appearance of the exposed bone in the socket, due to disintegration or loss of the blood clot. It is basically a focal osteomyelitis without suppuration and is accompanied by severe pain (alveolalgia) and foul odor. (Dorland, 28th ed)Air Conditioning: The maintenance of certain aspects of the environment within a defined space to facilitate the function of that space; aspects controlled include air temperature and motion, radiant heat level, moisture, and concentration of pollutants such as dust, microorganisms, and gases. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Sarcoidosis: An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.Respiratory Function Tests: Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.Therapeutic Irrigation: The washing of a body cavity or surface by flowing water or solution for therapy or diagnosis.Lung Diseases: Pathological processes involving any part of the LUNG.Connective Tissue Diseases: A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.Lung Diseases, Interstitial: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.Asbestosis: A form of pneumoconiosis caused by inhalation of asbestos fibers which elicit potent inflammatory responses in the parenchyma of the lung. The disease is characterized by interstitial fibrosis of the lung, varying from scattered sites to extensive scarring of the alveolar interstitium.Dust: Earth or other matter in fine, dry particles. (Random House Unabridged Dictionary, 2d ed)Air Microbiology: The presence of bacteria, viruses, and fungi in the air. This term is not restricted to pathogenic organisms.Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.Pulmonary Diffusing Capacity: The amount of a gas taken up, by the pulmonary capillary blood from the alveolar gas, per minute per unit of average pressure of the gradient of the gas across the BLOOD-AIR BARRIER.Sulfamethoxypyridazine: A sulfanilamide antibacterial agent.Precipitins: Antibodies which elicit IMMUNOPRECIPITATION when combined with antigen.Vital Capacity: The volume of air that is exhaled by a maximal expiration following a maximal inspiration.Immune Complex Diseases: Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.Macrophages, Alveolar: Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.Micromonosporaceae: A family of gram-positive, saprophytic bacteria occurring in soil and aquatic environments.CD4-CD8 Ratio: Ratio of T-LYMPHOCYTES that express the CD4 ANTIGEN to those that express the CD8 ANTIGEN. This value is commonly assessed in the diagnosis and staging of diseases affecting the IMMUNE SYSTEM including HIV INFECTIONS.Parakeets: Common name for one of five species of small PARROTS, containing long tails.Wood: A product of hard secondary xylem composed of CELLULOSE, hemicellulose, and LIGNANS, that is under the bark of trees and shrubs. It is used in construction and as a source of CHARCOAL and many other products.Lung Volume Measurements: Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.Pantoea: A genus of gram-negative, facultatively anaerobic, straight rods which are motile by peritrichous flagella. Most strains produce a yellow pigment. This organism is isolated from plant surfaces, seeds, soil, and water, as well as from animals and human wounds, blood, and urine. (From Bergey's Manual of Determinative Bacteriology, 9th ed)Occupational Diseases: Diseases caused by factors involved in one's employment.Industrial Waste: Worthless, damaged, defective, superfluous or effluent material from industrial operations.Neutrophils: Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.Gallium Radioisotopes: Unstable isotopes of gallium that decay or disintegrate emitting radiation. Ga atoms with atomic weights 63-68, 70 and 72-76 are radioactive gallium isotopes.Air Pollutants, Occupational: Air pollutants found in the work area. They are usually produced by the specific nature of the occupation.Cyanates: Organic salts of cyanic acid containing the -OCN radical.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Agricultural Workers' Diseases: Diseases in persons engaged in cultivating and tilling soil, growing plants, harvesting crops, raising livestock, or otherwise engaged in husbandry and farming. The diseases are not restricted to farmers in the sense of those who perform conventional farm chores: the heading applies also to those engaged in the individual activities named above, as in those only gathering harvest or in those only dusting crops.Saccharopolyspora: A genus of gram-positive bacteria whose spores are round to oval and covered by a sheath.Pneumonia: Infection of the lung often accompanied by inflammation.Leukocyte Count: The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.Technetium Tc 99m Pentetate: A technetium imaging agent used in renal scintigraphy, computed tomography, lung ventilation imaging, gastrointestinal scintigraphy, and many other procedures which employ radionuclide imaging agents.Cell Count: The number of CELLS of a specific kind, usually measured per unit volume or area of sample.Occupational Exposure: The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.Antigen-Antibody Complex: The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.Aerosols: Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.Tooth Extraction: The surgical removal of a tooth. (Dorland, 28th ed)Berylliosis: A form of pneumoconiosis caused by inhaled rare metal BERYLLIUM or its soluble salts which are used in a wide variety of industry including alloys, ceramics, radiographic equipment, and vacuum tubes. Berylliosis is characterized by an acute inflammatory reaction in the upper airway leading to BRONCHIOLITIS; PULMONARY EDEMA; and pneumonia.Allergens: Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Radiography, Thoracic: X-ray visualization of the chest and organs of the thoracic cavity. It is not restricted to visualization of the lungs.Dyspnea: Difficult or labored breathing.Skin Transplantation: The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.Biopsy: Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.Lymphocytes: White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.Respiratory Hypersensitivity: A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL.Equipment Contamination: The presence of an infectious agent on instruments, prostheses, or other inanimate articles.Pulmonary Emphysema: Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.Bronchoscopy: Endoscopic examination, therapy or surgery of the bronchi.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Preexisting Condition Coverage: Insurance coverage of a physical or mental health condition, disability, or illness existing before health insurance is applied for or enrolled in.Bronchial Arteries: Left bronchial arteries arise from the thoracic aorta, the right from the first aortic intercostal or the upper left bronchial artery; they supply the bronchi and the lower trachea.Inhalation Exposure: The exposure to potentially harmful chemical, physical, or biological agents by inhaling them.Lymphocyte Subsets: A classification of lymphocytes based on structurally or functionally different populations of cells.Bronchitis: Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.Chemotaxis, Leukocyte: The movement of leukocytes in response to a chemical concentration gradient or to products formed in an immunologic reaction.Macrophages: The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)Acute Disease: Disease having a short and relatively severe course.Autoantibodies: Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.Eosinophils: Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.Forced Expiratory Volume: Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.Immunoglobulins: Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.Death Certificates: Official records of individual deaths including the cause of death certified by a physician, and any other required identifying information.Confidence Intervals: A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.Bleomycin: A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.Smoking: Inhaling and exhaling the smoke of burning TOBACCO.Great BritainEpithelium: One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.Diagnostic Errors: Incorrect diagnoses after clinical examination or technical diagnostic procedures.Interleukin-8: A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.Peptidyl-Dipeptidase A: A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. It may also have endopeptidase activity on some substrates. (From Enzyme Nomenclature, 1992) EC 3.4.15.1.Reference Values: The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.

Hypersensitivity pneumonitis: experimental production in calves with antigens of Micropolyspora faeni. (1/291)

Pneumonitis was induced in calves by exposure to aerosols of Micropolyspora faeni with or without prior sensitization of the animals by subcutaneous injection of antigen. The pneumonitis primarily involved centrolobular areas and was characterized by alveolar septal thickening and loss of air space by cellular infiltration. Vasculitis and focal haemorrhage occurred in certain individuals and haemoproteinaceous exudate appeared within septa and alveolar lumina. The pneumonitis was compared with human farmer's lung, pneumonitis of housed cattle and other experimental hypersensitivity pneumonitides.  (+info)

Mushroom worker's lung resulting from indoor cultivation of Pleurotus osteatus. (2/291)

Indoor cultivation of oyster mushroom Pleurotus osteatus lead to an outbreak of extrinsic allergic alveolitis in two workers. High titer of indirect fluorescent antibody and positive precipitins against basidiospores of P. osteatus were demonstrated in sera of the patients. Mushroom workers should protect themselves from the basidiospores, being aware of their pathogenicity.  (+info)

Compliance and stability of the bronchial wall in a model of allergen-induced lung inflammation. (3/291)

Airway wall remodeling in response to inflammation might alter load on airway smooth muscle and/or change airway wall stability. We therefore determined airway wall compliance and closing pressures in an animal model. Weanling pigs were sensitized to ovalbumin (OVA; ip and sc, n = 6) and were subsequently challenged three times with OVA aerosol. Control pigs received 0.9% NaCl (n = 4) in place of OVA aerosol. Bronchoconstriction in vivo was assessed from lung resistance and dynamic compliance. Semistatic airway compliance was recorded ex vivo in isolated segments of bronchus, after the final OVA aerosol or 0.9% NaCl challenge. Internally or externally applied pressure needed to close bronchial segments was determined in the absence or presence of carbachol (1 microM). Sensitized pig lungs exhibited immediate bronchoconstriction to OVA aerosol and also peribronchial accumulations of monocytes and granulocytes. Compliance was reduced in sensitized bronchi in vitro (P < 0.01), and closing pressures were increased (P < 0.05). In the presence of carbachol, closing pressures of control and sensitized bronchi were not different. We conclude that sensitization and/or inflammation increases airway load and airway stability.  (+info)

Regulatory effects of endogenous protease inhibitors in acute lung inflammatory injury. (4/291)

Inflammatory lung injury is probably regulated by the balance between proteases and protease inhibitors together with oxidants and antioxidants, and proinflammatory and anti-inflammatory cytokines. Rat tissue inhibitor of metalloprotease-2 (TIMP-2) and secreted leukoprotease inhibitor (SLPI) were cloned, expressed, and shown to be up-regulated at the levels of mRNA and protein during lung inflammation in rats induced by deposition of IgG immune complexes. Using immunoaffinity techniques, endogenous TIMP-2 in the inflamed lung was shown to exist as a complex with 72- and 92-kDa metalloproteinases (MMP-2 and MMP-9). In inflamed lung both TIMP-2 and SLPI appeared to exist as enzyme inhibitor complexes. Lung expression of both TIMP-2 and SLPI appeared to involve endothelial and epithelial cells as well as macrophages. To assess how these endogenous inhibitors might affect the lung inflammatory response, animals were treated with polyclonal rabbit Abs to rat TIMP-2 or SLPI. This intervention resulted in significant intensification of lung injury (as revealed by extravascular leak of albumin) and substantially increased neutrophil accumulation, as determined by cell content in bronchoalveolar lavage (BAL) fluids. These events were correlated with increased levels of C5a-related chemotactic activity in BAL fluids, while BAL levels of TNF-alpha and chemokines were not affected by treatment with anti-TIMP-2 or anti-SLPI. The data suggest that endogenous TIMP-2 and SLPI dynamically regulate the intensity of lung inflammatory injury, doing so at least in part by affecting the generation of the inflammatory mediator, C5a.  (+info)

Mycobacterium sp. as a possible cause of hypersensitivity pneumonitis in machine workers. (5/291)

Hypersensitivity pneumonitis (HP) in workers exposed to metal removal fluids (MRFs) is increasing. This study supports the hypothesis that aerosolized mycobacteria colonizing the MRFs likely cause the disease. Three case studies of HP outbreaks among metal workers showed potentially high exposures to a rare and newly proposed Mycobacterium species. Retrospective review of samples submitted to our laboratory showed an association between presence of mycobacteria and HP.  (+info)

Expression of mucosa-related integrin alphaEbeta7 on alveolar T cells in interstitial lung diseases. (6/291)

The expression of alphaEbeta7 integrin has been related to the selective retention of lymphocytes in mucosal tissues of gut, urogenital tract and lung. To identify potential disease-associated alphaEbeta7 expression patterns on cells accounting for lymphocytic alveolitis in interstitial lung disease (ILD), alphaE expression on CD4+ and CD8+ T cell subsets was evaluated by dual-colour flow cytometry in peripheral blood and bronchoalveolar lavage fluid (BALF) of patients with idiopathic pulmonary fibrosis (IPF; n = 18), hypersensitivity pneumonitis (HP; n = 20) and sarcoidosis (n = 44) in comparison with healthy controls (n = 15). In both healthy individuals and all patient groups the proportion of alphaE-bearing T cells in peripheral blood was < 2%, whereas the vast majority of alveolar CD8+ T cells consistently co-expressed alphaE. Absolute alveolar CD8+alphaE+ cell numbers/ml were up to 30-fold increased in HP patients. Proportions of alphaE-bearing CD4+ cells in BALF were significantly elevated in IPF (74.0 +/- 2.7%) and HP (70.0 +/- 2.4%) compared with normals (30.0 +/- 1.8%) (mean +/- s.e.m.; P < 0.01). In sarcoidosis, the alphaE expression on BALF CD4+ cells displayed subgroup dependency: proportions significantly lower than normal were noted in chest radiographic stage I (14.3 +/- 1.5%), but increased proportions in stages II (50.0 +/- 3.8%) and III (64.0 +/- 4.8%). Correlations between common markers of T cell activation or BALF transforming growth factor-beta (TGF-beta ) bioactivity and alphaE expression were not noted. We conclude that the vast majority of alveolar CD8+ T cells consistently express alphaEbeta7 and that distinct patterns of alphaEbeta7 expression on alveolar CD4+ lymphocytes in sarcoidosis are related to the diverse manifestations of the sarcoid inflammatory process in the lung.  (+info)

Viral infection modulates expression of hypersensitivity pneumonitis. (7/291)

Hypersensitivity pneumonitis (HP) is a granulomatous, inflammatory lung disease caused by inhalation of organic Ags, most commonly thermophilic actinomycetes that cause farmer's lung disease. The early response to Ag is an increase in neutrophils in the lung, whereas the late response is a typical Th1-type granulomatous disease. Many patients who develop disease report a recent viral respiratory infection. These studies were undertaken to determine whether viruses can augment the inflammatory responses in HP. C57BL/6 mice were exposed to the thermophilic bacteria Saccharopolyspora rectivirgula (SR) for 3 consecutive days per wk for 3 wk. Some mice were exposed to SR at 2 wk after infection with respiratory syncytial virus (RSV), whereas others were exposed to SR after exposure to saline alone or to heat-inactivated RSV. SR-treated mice developed a typical, early neutrophil response and a late granulomatous inflammatory response. Up-regulation of IFN-gamma and IL-2 gene expression was also found during the late response. These responses were augmented by recent RSV infection but not by heat-inactivated RSV. Mice with a previous RSV infection also had a greater early neutrophil response to SR, with increased macrophage inflammatory protein-2 (MIP-2, murine equivalent of IL-8) release in bronchoalveolar lavage fluid. These studies suggest that viral infection can augment both the early and late inflammatory responses in HP.  (+info)

Polarized type 1 cytokine profile in bronchoalveolar lavage T cells of patients with hypersensitivity pneumonitis. (8/291)

Hypersensitivity pneumonitis (HP) is characterized by an inflammatory lymphocytic alveolitis comprised of both CD8+ and CD4+ T cells. Animal models suggest that HP is facilitated by overproduction of IFN-gamma, and that IL-10 ameliorates severity of the disease, indicating a Th1-type response. To determine whether a Th1 phenotype in HP also exists clinically, bronchoalveolar lavage (BAL) and peripheral blood (PB) T cells were obtained from HP individuals and analyzed for Th1 vs Th2 cytokine profiles. It was determined that soluble OKT3-stimulated BAL T cells cocultured with alveolar macrophages produced more IFN-gamma and less IL-10 than PB T cells cocultured with monocytes, but no difference was observed in IL-4 production. The monocytic cells did not account for this difference, as CD80 and CD86 expressions were similar, and coculturing PB T cells with alveolar macrophages resulted in no difference in IFN-gamma production. Similarly, there was no difference in IL-12 production between stimulated BAL or PB T cells; however, addition of rIL-12 significantly increased production of IFN-gamma by BAL T cells, but not by PB T cells. This effect was due to a difference in IL-12R expression. High affinity IL-12R were only present in association with BAL T cells. These studies indicate that clinical HP is characterized by a predominance of IFN-gamma-producing T cells, perhaps resulting from a reduction in IL-10 production and an increase in high affinity IL-12R compared with blood T cells.  (+info)

*Hypersensitivity pneumonitis

... (HP; also called allergic alveolitis or extrinsic allergic alveolitis, EAA) is an inflammation of ... Extrinsic allergic alveolitis may eventually lead to Interstitial lung disease. Patients with subacute HP gradually develop a ... Ismail T, McSharry C, Boyd G (2006). "Extrinsic allergic alveolitis". Respirology. 11 (3): 262-8. doi:10.1111/j.1440-1843.2006. ... abcnews.go.com/Health/study-brass-wind-instruments-allergic-lung-disease/story?id=11569520&page=2 [1] Oxford Handbook of ...

*Lycoperdonosis

It is classified as a hypersensitivity pneumonitis (also called extrinsic allergic alveolitis)-an inflammation of the alveoli ... Barrios R. (2008). "Hypersensitivity pneumonitis (extrinsic allergic alveolitis)". Dail and Hammar's Pulmonary Pathology (3rd ...

*Neurosarcoidosis

Warren, C. P. (1977). "Extrinsic allergic alveolitis: a disease commoner in non-smokers" (PDF). Thorax. 32 (5): 567-569. doi: ...

*Wheeze

Earis JE, Marsh K, Pearson MG, Ogilvie CM (Dec 1982). "The inspiratory "squawk" in extrinsic allergic alveolitis and other ... Today one child in four is allergic.[citation needed] Early diagnosis of allergy is important for the development of the child ... One out of 3 preschool children and 2 out of 3 school children with recurrent wheezing/coughing are allergic.[citation needed] ...

*Aspergillus clavatus

Extrinsic allergic alveolitis (EAA) is also caused by Aspergillus clavatus with a Type 1 immune reaction. It is described as a ... A. clavatus is known as an agent of allergic aspergillosis and has been implicated in multiple pulmonary infections. It has ...

*Squawk (sound)

The inspiratory "squawk" in extrinsic allergic alveolitis and other pulmonary fibroses. Thorax 1979;37:923-926. Paciej R, ... They are also heard in a variety of conditions in which alveolitis is present. In one study they were found in 10% of patients ...

*Aureobasidium pullulans

... extrinsic allergic alveolitis) or "humidifier lung". This condition is characterized acutely by dyspnea, cough, fever, chest ...

*Sick building syndrome

Extrinsic allergic alveolitis has been associated with the presence of fungi and bacteria in the moist air of residential ... Adult SBS symptoms were associated with a history of allergic rhinitis, eczema and asthma. A 2015 study concerning the ...

*List of MeSH codes (C08)

... alveolitis, extrinsic allergic MeSH C08.381.483.125.125 --- bird fancier's lung MeSH C08.381.483.125.365 --- farmer's lung MeSH ... allergic, perennial MeSH C08.460.799.633 --- rhinitis, allergic, seasonal MeSH C08.460.799.649 --- rhinitis, atrophic MeSH ... allergic bronchopulmonary MeSH C08.730.435.700 --- pneumonia, pneumocystis MeSH C08.730.450.314 --- echinococcosis, pulmonary ... allergic bronchopulmonary MeSH C08.381.472.700 --- pneumonia, pneumocystis MeSH C08.381.483.125 --- ...

*List of MeSH codes (C20)

... alveolitis, extrinsic allergic MeSH C20.543.480.680.075.125 --- bird fancier's lung MeSH C20.543.480.680.075.365 --- farmer's ... allergic, perennial MeSH C20.543.480.680.795 --- rhinitis, allergic, seasonal MeSH C20.543.480.904 --- urticaria MeSH C20.543. ... allergic cutaneous MeSH C20.673.430.500 --- iga deficiency MeSH C20.673.430.750 --- igg deficiency MeSH C20.673.480.040 --- ... allergic MeSH C20.543.480.343 --- dermatitis, atopic MeSH C20.543.480.370 --- food hypersensitivity MeSH C20.543.480.370.150 ...

*List of diseases (A)

... extrinsic allergic Alves Dos Santos Castello syndrome Alzheimer's disease Alzheimer's disease, early-onset Alzheimer's disease ... of childhood Aluminium lung Alveolar capillary dysplasia Alveolar echinococcosis Alveolar soft part sarcoma Alveolitis, ... McLeod syndrome Allergic angiitis Allergic autoimmune thyroiditis Allergic bronchopulmonary aspergillosis Allergic ...

*Pneumonitis

... also known as extrinsic allergic alveolitis (EAA) "pneumonitis" at Dorland's Medical Dictionary Stedman's medical dictionary ( ... bronchoalveolar allergic syndrome) Mercury exposure Smoking Overexposure to chlorine Bronchial obstruction (obstructive ...

*Bilateral hilar lymphadenopathy

Malignancy Lymphoma Carcinoma Mediastinal tumors Inorganic dust disease Silicosis Berylliosis Extrinsic allergic alveolitis ... Eosinophilic granulomatosis with polyangiitis Human immunodeficiency virus Extrinsic allergic alveolitis Adult-onset Still's ...

*Fever of unknown origin

... emboli Complex partial status epilepticus Cyclic neutropenia Drug fever Erdheim-Chester disease Extrinsic allergic alveolitis ...

*List of ICD-9 codes 460-519: diseases of the respiratory system

Extrinsic allergic alveolitis (496) Chronic airway obstruction, not elsewhere classified (496.0) COPD, Not Otherwise Specified ... allergic, due to pollen (477.2) Rhinitis, allergic, due to animal dander (477.9) Rhinitis, allergic, cause unspec. (478) Other ... 475) Peritonsillar abscess (476) Chronic laryngitis and laryngotracheitis (476.0) Laryngitis, chronic (477) Allergic rhinitis ( ... Idiopathic fibrosing alveolitis Hamman-Rich syndrome (517) Lung involvement in conditions classified elsewhere (517.1) ...

*EAA

... primarily for vintage and homebuilt aircraft enthusiasts Extrinsic allergic alveolitis, also known as hypersensitivity ...
The objective of this study was to develop a diagnostic model that allows for a highly specific diagnosis of chronic hypersensitivity pneumonitis using clinical and radiological variables alone. Chronic hypersensitivity pneumonitis and other interstitial lung disease cases were retrospectively identified from a longitudinal database. High-resolution CT scans were blindly scored for radiographic features (eg, ground-glass opacity, mosaic perfusion) as well as the radiologists diagnostic impression. Candidate models were developed then evaluated using clinical and radiographic variables and assessed by the cross-validated C-statistic. Forty-four chronic hypersensitivity pneumonitis and eighty other interstitial lung disease cases were identified. Two models were selected based on their statistical performance, clinical applicability and face validity. Key model variables included age, down feather and/or bird exposure, radiographic presence of ground-glass opacity and mosaic perfusion and ...
Johannes J, Rezayat T, Wallace WD, Lynch JP, Chronic Hypersensitivity Pneumonitis Associated with Inhaled Exposure to Nylon Powder for 3-D Printing: A Variant of Nylon Flock Workers Lung Disease?, Am J Respir Crit Care Med, 2016;193:A7071,http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2016.193.1_MeetingAbstracts.A7071 ...
... extrinsic allergic alveolitis n. Pneumoconiosis resulting from hypersensitivity to inhaled organic dust.
Objective To estimate the reported incidence of occupational hypersensitivity pneumonitis (OHP) in the UK and to consider whether the pattern of attributed causation has changed over time. Methods All cases of OHP reported to the SWORD scheme between January 1996 and December 2015 were classified into 1 of 10 categories of the suspected agent. Cases were grouped into four 5-year time periods to examine any changing pattern in incidence or suspected causation. For each time period, the annual incidence was calculated using the estimated number of reported cases and the working population of the UK. Results Between 1996 and 2015, there were 202 actual cases of OHP reported to SWORD, equating to an estimated 818 cases, when adjusting for the sampling ratio. Over this period, the annual UK incidence was 1.4 per million workers. The mean (SD) age of reported cases was 52 (13) years, and cases were four-times more likely to be men than women. Over the study period, there was a fall in the proportion ...
Extrinsic allergic alveolitis is an uncommon inflammatory disorder of the lungs that results from hypersensitivity responses to inhaled environmental agents. Most varieties are occupational in origin, but sporadic cases arise in domestic settings or from recreational activities. Causal agents chiefly comprise allergenic microbial spores that contaminate stored vegetable produce (e.g. farmers lung caused by ...
Diagnosis and conservative treatment of extrinsic allergic alveolitis (costs for program #126725) ✔ University Hospital Rechts der Isar of the Munich Technical University ✔ Department of Pediatrics ✔ BookingHealth.com
Association between pulmonary disease and IgA nephropathy (IgAN) has been previously reported. However, no association has been reported between hypersensitivity pneumonitis (HP) and IgAN. Here, we report about a patient with no particular medical history, who experienced worsening dyspnoea in the course of 1 month, with ground-glass opacity on chest CT and no improvement after antibiotic therapy. The patient was diagnosed as having HP based on the history of antigen exposure, detection of Trichosporon asahii-specific antibodies and bronchoscopy findings. Concomitantly, findings of renal biopsy revealed the IgAN diagnosis. The patient underwent corticosteroid therapy, with good outcomes for both HP and IgAN. This is the first report in the literature to describe summer-type HP complicated with IgAN. ...
Hypersensitivity pneumonitis is a condition where the lungs become infalmmed due to exposure to an environmental allergen to which the individual has ben previously sensitized. Symptoms: dyspnea cough The disease may be of chronic nature with symptoms lasting more than a year (Lynch et al, 1995). The disease may be chronic and progressive. In some cases…
An esparto dust extract was made with several samples from the esparto fibers of the patients. These samples were crushed to obtain a thin dusty material. Two grams of this dusty material were diluted in 20 ml of phosphate-buffered saline (PBS). The solution was shaken for 24 hours and then passed through a 0.22 ttm Millipore filter (Millipore Corp., Bedford, Mass.) The samples of esparto grass provided by the patients were investigated to identify the presence of microorganisms. The cultures showed a luxuriant growth of Aspergillus fumigatus. We looked for and found other esparto fibers which was not contaminated with molds, and then we performed another extract by the same method.. Skin prick tests with theses extracts, and with a battery of common inhalants were performed. Skin prick testing was negative in father, son 1 and son 2. In sons 3 and 4 skin prick tests were positive to grass pollen. They did not tell any spring-related symptom.. Intradermal test with the fungi-contaminated esparto ...
Significant advances have been noticed in the pathogenesis and the diagnosis of extrinsic allergic alveolitis during the last few years. Indeed the immune mechanism and the enabling conditions have been more precisely defined, the clinical stages and the diagnosis criterias clearly defined, new antigens incriminated and some etiological agents have been reclassified. The present pathogenic explanation insists on the type IV hypersensitivity reaction with sensitization of T lymphocytes, activation macrophages, the formation of IgG type antibodies and immune complexes, activation of complement and secretion of cytokines. The involvement of certain HLA classes (HLA2, DR3, DRB1, DQB1), interaction of genetics and environments factors, the role of infections agents and smoking have been demonstrated in several studies. The development of news clinical and biological diagnosis criteria have led the discovery of new extrinsic allergic alveolitis in the work places, a better knowledge of the prognostic elements
Hypersensitivity pneumonitis (HP), also referred to as extrinsic allergic alveolitis, is a pulmonary disease that occurs due to inhalational exposure to a variety of antigens leading to an inflammatory response of the alveoli and small airways. Systemic manifestations such as fever and fatigue can accompany respiratory symptoms. Although sensitization to an inhaled antigen as manifested by specific circulating IgG antibodies is necessary for the development of HP, sensitization alone is not sufficient as a defining characteristic, because many sensitized individuals do not develop HP. The incidence and prevalence of HP are variable, depending on geography, occupation, avocation, and environment of the cohort being studied. As yet unexplained is the decreased risk of developing HP in smokers. ...
Mayfair Veterinary Clinic, Hobart Allergic alveolitis is a respiratory disease of humans. It is the result of a hypersensitivity to avian antigens. This includes serum, feathers, feather dust, and faecal material. The condition is also called hypersensitivity pneumonitis, bronchiolitis, allergic interstitial pneumonitis, parakeet dander pneumoconiasis, acute psittacokeratopneumoconiosis, and pigeon lung disease. There are acute, subacute, and chronic forms of this disease. The acute form occurs 4 to 8 hours after exposure to a heavy load of avian antigen, such as cleaning out a chook house. Coughing, difficulty breathing, fever, and chills occur. There are rattling sounds when breathing in, and an increase in white blood cells, especially eosinophils. X-rays of the lungs show changes consistent with allergic response. Attacks subside within 24 hours without treatment. The condition is confirmed by the history of exposure and by a skin test. The subacute form results from long-term exposure to a ...
A cross sectional industrial hygiene and medical study was conducted at a mushroom farm in Florida where seven cases of mushroom workers lung (MWL), a form of hypersensitivity pneumonitis, were reported between April 1982 and August 1985. Typically, the episodes started with mild symptoms which increased in severity and frequency, culminating in a severe attack. Severe attacks were characterized
A 41-year-old automobile paint sprayer showed the clinical features of hypersensitivity pneumonitis 1 week after he had begun to work with paint materials containing toluene diisocyanate. His symptoms began 6 to 8 hours after exposure to the agent and spontaneously disappeared by the next morning. He had diffuse, fine reticulonodular shadows on a chest roentgenogram and a restrictive impairment of pulmonary function. Immunoglobulin G antibody to toluene diisocyanate-human serum albumin was present in bronchoalveolar lavage fluid and sera; IgA antibody was present only in bronchoalveolar lavage fluid. Also, the patient had sensitized bronchoalveolar lymphocytes to toluene diisocyanateserum albumin. The histologic findings suggested hypersensitivity pneumonitis. The results of bronchoalveolar lavage, which was repeated on four separate occasions, showed lymphocytosis and a predominance of suppressorcytotoxic T cells. The findings from serial determinations of humoral antibodies showed no changes ...
Objective: To identify the cause of a hypersensitivity pneumonitis and to determine its pathogenesis.. ▪Design: Case study.. ▪Setting: Intensive care unit of a referral hospital.. ▪Patient: A 51-year-old man with chronic bronchitis who developed a hypersensitivity pneumonitis within 1 month after exposure to minocycline, amoxicillin, and erythromycin.. ▪Intervention: Sequential bronchoalveolar lavages after reexposure to minocycline and amoxicillin.. ▪Measurements: Immunologic analysis of the phenotype and function of alveolar lymphocytes.. ▪Results: Reexposure to minocycline but not to amoxicillin was followed by an interstitial pneumonitis. Sequential bronchoalveolar lavages showed a transient rise of eosinophils and neutrophils and a persistent alveolar lymphocytosis. Alveolar lymphocytes consisted predominantly of CD8+ but also CD4+ cells. Two C08+ lymphocyte subsets were identified: CD8+ D44+ cytotoxic T cells that increased rapidly after the drug was resumed and CD8+ CD57+ ...
Persensitivity pneumonitis (HP), also known as extrinsic allergic alveolitis, is a complex condition of varying intensity, clinical presentation, and. Results in itchy, red, swollen, and cracked skin. Neutropenia is a reduction in the blood neutrophil count? Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin. ContainerTube: Preferred: Red top Acceptable: Serum gel Collection instructions: Draw blood in a plain, red top tube(s), serum gel tube(s) is acceptable. Epared by William G! About Idiopathic Pulmonary Fibrosis Idiopathic pulmonary fibrosis (IPF) is a condition in which, over a period of time, lung tissue becomes thickened, stiff and scarred. Eveland, D.. Cal symptoms of. It is severe, the risk and severity of bacterial and fungal infections increase. Neutropenia is a reduction in the blood neutrophil count. About Idiopathic Pulmonary Fibrosis Idiopathic pulmonary fibrosis (IPF) is a condition in which, over a period of time, lung tissue becomes ...
Principal Investigator:UEDA Atsushi, Project Period (FY):1990 - 1992, Research Category:Grant-in-Aid for General Scientific Research (B), Research Field:Hygiene
Hypersensitivity pneumonitis (HP) refers to a group of disorders caused by a nonatopic immunologic response to an inhaled agent. In its acute or subacute form, hypersensitivity pneumonitis may be a cause of recurrent pneumonitis.
What is Hypersensitivity Pneumonitis? "Umm... excuse me, did you say Supercalifragilisticexpialidocious...???" Nope! We said Hypersensitivity Pneumonitis (HP) [click here for pronunciation], but we completely understand your confusion. So, what is ...
Hypersensitivity pneumonitis (HP), also referred to as extrinsic allergic alveolitis (EAA), is an inflammatory lung disease resulting from the inhalation and subsequent sensitization to a wide variety of inhaled organic dusts.1-5 HP is not mediated by IgE. It is associated with progressive pulmonary disability, irreversible lung damage, and mortality in some occupational settings.1-5 Patients often present with intermittent chills, fever, cough, and shortness of breath that begin four to eight hours after exposure to the offending dust. Aspergillus mold can be found in soil, foods, fresh water, and other natural sources including compost, barley, tobacco, and Esparto grass dust (stucco).1,3,5 These organisms grow well in decaying organic material at temperatures often attained during decomposition.5Aspergillus mold can also grow on ceiling and walls where water damage has occurred.6. No single laboratory test is diagnostic for hypersensitivity pneumonitis.1-5 Diagnosis is based on a complete ...
Can methods less invasive than SLB, including BAL and TBB, be useful in the diagnosis of IPF? The short answer is no. BAL cellular analysis has been used for many years in the diagnosis of several ILDs. When evaluating individuals with suspected IPF, BAL is useful in excluding other conditions, especially chronic hypersensitivity pneumonitis, for which a diagnosis is suggested by a lymphocytosis ,40% [2]. A recent publication of retrospective data reported that 8% of individuals with a HRCT UIP pattern may have BAL features that would point to an alternative diagnosis to IPF [2, 15]. The 2011 guidelines recommend, however, that BAL cellular analysis should not be performed in the diagnostic evaluation of IPF in the majority of individuals, but may be appropriate for a minority. The evidence regarding whether or not BAL adds significantly improved diagnostic specificity is presently unclear [2].. TBB has been shown to be useful in the evaluation of conditions that are predominantly bronchocentric ...
Norman Woodward, 75, a poultry farmer from Sandbach, Cheshire, United Kingdom, died from lung disease after a lifetime exposure to chicken waste.. Coroner, Dr. Geoff Roberts, said Normans illness was linked to his time working with poultry.. Norman became ill and increasingly short of breath after his retirement aged 64.. According to Dr. Roberts, Norman exposure to a number of antigens in poultry over the years resulted to develop him the condition of allergic alveolitis. After continued exposure, he developed the lung disease associated with his occupation, and theres no doubt that these led him to his death, said Dr. Roberts.. His widow Heather told during the court hearing at Crewe Law Courts, Cheshire, that she remember once Norman came covered hand to foot in chicken muck.. According to her, on occasions the silage tower would get blocked and he would have to go and find where the blockage was. All he would wear was his own cap, his boiler suit and his rubber boots.. Theres a very ...
Alveolitis can refer to two inflammatory conditions. It can refer to inflammation of the alveoli in the lungs, or the dental alveolus in the jaw. Extrinsic allergic alveolitis is a lung disorder resulting from repeated inhalation of organic dust, usually in a specific occupational setting. In the acute form, respiratory symptoms and fever begin several hours after exposure to the dust. The chronic form is characterized by gradual changes in the lung tissue associated with several years of exposure to the irritant. ...
Quirce S, Vandenplas O, Campo P, Cruz MJ, de Blay F, Koschel D, Moscato G, Pala G, M R, Sastre J, Siracusa A, Tarlo SM, Walusiak-Skorupa J, Cormier Y, Occupational hypersensitivity pneumonitis: An EAACI Position paper, Allergy, 2016;:,10.1111/all.12866 ...
Hypersensitivity pneumonitis (HP) was identified among employees in an automobile parts manufacturing facility. Mycobacteria immunogenum (MI) was identified as a metal removal fluid (MRF) contaminant at this facility and had been identified as a contaminant in other facilities where HP had occurred. We therefore questioned whether measurement of MI-specific cell-mediated immunity would be associat
Hypersensitivity pneumonitis. This is an allergic lung disease caused by a lung inflammation that happens from breathing in many different substances including fungus spores, bacteria, animal or plant protein, or specific chemicals. They can come from moldy hay, bird droppings, and other organic dusts. The disease causes inflamed air sacs in the lungs, and leads to fibrous scar tissue in the lungs and trouble breathing. There are variations of this disease depending on the job. They include cork workers lung, farmers lung, and mushroom workers lung ...
Detergent workers lung, grain handlers lung, and bird breeders lung are part of a group of occupational respiratory illnesses that fall under the umbrella of extrinsic allergic alveolitis.
Wilson, B D.; Sternick, J L.; Yoshizawa, Y; Katzenstein, A; and Moore, V L., "Experimental murine hypersensitivity pneumonitis: multigenic control and influence by genes within the i-b subregion of the h-2 complex." (1982). Subject Strain Bibliography 1982. 3795 ...
Beryllium. Radiation. Extrinsic allergic alveolitis. Ankylosing spondylitis. Sarcoidosis. TB. Scoliosis. Coal workers pneumoconiosis. ...
Occupational asthma is an occupational lung disease and a type of asthma. Like other types of asthma, it is characterized by airway inflammation, reversible airways obstruction, and bronchospasm, but it is caused by something in the workplace environment. Symptoms include shortness of breath, tightness of the chest, nasal irritation, coughing and wheezing. The first person to use it in reference to a medical condition was Hippocrates, and he believed that tailors, anglers and metalworkers were more likely to be affected by the disease. Although much research has been done since, the inflammatory component of asthma was recognized only in the 1960s. Hypersensitivity pneumonitis is a related condition, with many occupational examples (e.g. flock workers lung, farmers lung, and indium lung). However, although overlapping in many cases, hypersensitivity pneumonitis may be distinguished from occupational asthma in that it isnt restricted to only occupational exposure, and involves type III ...
Environmental opportunistic mycobacteria, including Mycobacterium avium, M. terrae, and the new species M. immunogenum, have been implicated in outbreaks of hypersensitivity pneumonitis or respiratory problems in a wide variety of settings. One common feature of the outbreaks has been exposure to aerosols. Aerosols have been generated from metalworking fluid during machining and grinding operations as well as from indoor swimming pools, hot tubs, and water-damaged buildings. Environmental opportunistic mycobacteria are present in drinking water, resistant to disinfection, able to provoke inflammatory reactions, and readily aerosolized. In all outbreaks, the water sources of the aerosols were disinfected. Disinfection may select for the predominance and growth of mycobacteria. Therefore, mycobacteria may be responsible, in part, for many outbreaks of hypersensitivity pneumonitis and other respiratory problems in the workplace and home ...
... u. ... .... _n of lung parenchyma by CD8+ cells ~hl!eOI~cut immunohistological observations f!CU:ii~J CD8+ infiltrate in the group of continued to ~ regularly exposed, and of CD4+ cells after 6 months in the lungs of were not. indicate that alveolitis in RP patients is a and its intensity might be modulated by to relevant antigens, amount of antigen of sensitization, thus explaining the BAL lymphocytosis observed in patients exposed to the specific antigens compared are noL Increased cells with supprcssor/cyin the lung of these patients is related to a local immunological response . These mechanisms may be relevant in the pathogenesis of HP.
If you know any web sites that contain more background information about this article, wed like to know about them. This could be a web site about the author, about a related institute, or also a link to a news article of related content. Let us know the URL and well include it on this page ...
Solid tumors involving glandular organs express mucin glycoprotein which is eventually shed into the circulation. As aresult these proteins can easily be measured in the serum and be used as potential tumor markers. The most commonly used tumor markers for breast cancer are CA 27-29 and CA 15-3, which both measure the glycoprotein product of the mucin-1 (MUC1) gene. CA 27-29 has been approved by the US Food and Drug Administration for monitoring disease activity in breast cancer patients. Most oncology clinical practice guidelines do not recommend the use of tumor markers for routine surveillance of early stage disease but recognize their utility in the metastatic setting ...
Container/Tube: Preferred: Red top Acceptable: Serum gel Collection instructions: Draw blood in a plain, red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 0.6 mL of serum refrigerated in a plastic vial.
The proportion of subjects who achieve a clinical response, defined as at least a 50% reduction in composite FLEET CAP score from baseline in each treatment group ...
Three physicians and researchers from the Capital University of Medical Sciences (Beijing, China) have published a case report in the  describing severe lung
Our studies, evaluating two dosing schedules, reveal that voreloxin is well tolerated and shows clinical activity in patients with a variety of advanced solid tumors. The primary DLT was neutropenia, which was noncumulative. Other toxicities were infrequent, and mild nausea was the main nonhematologic adverse event. In the SPO-0001 study, as anticipated, MP patients tolerated treatment better than HP patients, as shown by the higher MTD (60 versus 48 mg/m2). Based on these findings, the initial recommended phase 2 single-agent dose of voreloxin is 48 mg/m2 administered every 3 weeks in all patients with advanced solid tumors. In SPO-0002 (weekly administration), the MTD was defined as 15 mg/m2.. No differences were observed in the pharmacokinetic profiles for the two dosing schedules tested (once every 3 weeks or weekly for 3 weeks every 28 days). Voreloxin exhibited low clearance (2 L/h/m2) and a long terminal half-life (22 hours). Exposure to voreloxin increased linearly with dose, with no ...
Bird fanciers lung is a type of hypersensitivity pneumonitis caused by bird droppings. The lungs become inflamed with granuloma formation. Bird fanciers lung (BFL), also called bird-breeders lung and pigeon-breeders lung, is a subset of hypersensitivity pneumonitis (HP). This disease is caused by the exposure to avian proteins present in the dry dust of the droppings and sometimes in the feathers of a variety of birds. Birds such as pigeons, parakeets, cockatiels, shell parakeets (budgerigars), parrots, turtle doves, turkeys and chickens have been implicated. People who work with birds or own many birds are at risk. Bird hobbyists and pet store workers may also be at risk. This disease is an inflammation of the alveoli in the lungs. Initial symptoms are breathlessness especially after sudden exertion or when exposed to temperature change and can be very similar to asthma, hyperventilation syndrome or pulmonary embolism. One of the defining characteristics of bird fanciers lung is that many ...
Hypersensitivity pneumonitis may also be caused by fungi or bacteria in humidifiers, heating systems, and air conditioners found in homes and offices. Exposure to certain chemicals, such as isocyanates or acid anhydrides, can also lead to hypersensitivity pneumonitis.. Examples of hypersensitivity pneumonitis include:. Bird fanciers lung: This is the most common type of hypersensitivity pneumonitis. It is caused by repeated or intense exposure to proteins found in the feathers or droppings of many species of birds.. Farmers lung: This type of hypersensitivity pneumonitis is caused by exposure to dust from moldy hay, straw, and grain. ...
Looking for online definition of Farm Workers Lung in the Medical Dictionary? Farm Workers Lung explanation free. What is Farm Workers Lung? Meaning of Farm Workers Lung medical term. What does Farm Workers Lung mean?
Initial symptoms of hypersensitivity pneumonitis are similar to the flu, but it can take several months to a number of years to develop allergy to the dust. Certain occupations may increase your risk of developing hypersensitivity pneumonitis.
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The workforce at a biotechnology plant producing citric acid by fermentation of molasses with a strain of Aspergillus niger was studied. A combination of a respiratory questionnaire and clinical assessment identified 18 subjects (4.9% of the workforce) with work related bronchospasm. In nine of these evidence of sensitisation to A niger was obtained by skin prick tests and radioallergosorbent test (RAST) using as an antigen an extract of the A niger culture fluid from the process. Of the 325 subjects without work related bronchospasm, only nine (2.7%) had a positive prick test. There were no subjects with symptoms of extrinsic allergic alveolitis. Investigation into the source of the antigen showed that whereas, in some areas of the plant, A niger spores were present, in others there were no detectable spores. In these areas, however, extracts of filters from air samplers were shown by RAST inhibition to contain A niger antigens, indicating that the culture fluid was generating airborne antigen. ...
Aspergillosis comprises a spectrum of diseases caused by species of the fungal genus Aspergillus, including allergy (allergic bronchopulmonary aspergillosis, extrinsic allergic alveolitis),...
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Another name for Allergic Pneumonitis is Allergic Alveolitis. Home care for mild wheezing in a person with allergic alveolitis includes: * Avoid exposure ...
Popcorn Workers Lung Disease Prevention Act Report, Together With Minority Views (to Accompany H.R. 2693) (including Cost Estimate of the Congressional Budget Office) (Book) : United States
The first consumer to become afflicted by Popcorn Workers Lung has returned National Jewish Medical and Research Center for further testing. Since being di - November 1, 2007
Free, official information about 2012 (and also 2013-2015) ICD-9-CM diagnosis code 495.9, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.
http://www.ajronline.org/cgi/content/full/174/6/1745. Noriyuki Tomiyama ; Nestor L. Müller ; Takeshi Johkoh ; Osamu Honda ; Naoki Mihara ; Takenori Kozuka ; Seiki Hamada ; Hironobu Nakamura ; Masanori Akira ; Kazuya Ichikado. OBJECTIVE: The purpose of this study was to determine whether acute parenchymal lung diseases can be differentiated on the basis of the pattern and distribution of abnormalities revealed on high-resolution CT.. MATERIALS AND METHODS: High-resolution CT scans of 90 patients with acute parenchymal lung diseases (19 with bacterial pneumonia, 13 with mycoplasmal pneumonia, 21 with acute interstitial pneumonia, 18 with hypersensitivity pneumonitis, 10 with acute eosinophilic pneumonia, and nine with pulmonary hemorrhage) were independently assessed by two observes who had no knowledge of clinical or pathologic data. The observers recorded abnormalities, their first-choice diagnosis, and their degree of confidence in their first-choice diagnosis.. RESULTS: The two observers made ...
The following abstract describes a publication that is intended for print distribution or as a downloadable PDF. Please see links to the PDF file and ordering information on this page.. Cultivating shiitake mushrooms represents an opportunity to utilize healthy low-grade and small-diameter trees thinned from woodlots as well as healthy branch-wood cut from the tops of harvested saw-timber trees. When the mushrooms are collected and marketed, the result is a relatively short-term payback for long-term management of wooded areas.. The cultivation of shiitake mushrooms on solid wood requires a significant amount of shade and wind protection, but not a significant amount of acreage. Therefore it is an excellent opportunity for landowners with smaller acreages to utilize forested or shaded areas. Shiitake producers can often obtain wood for cultivation from land management agencies or private landowners. In addition to making productive use of woodlots and forested acres, logs that have been used for ...
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Colles fracture is a break across the end of the main bone of the forearm (the radius). A Colles fracture results in a backward and outward position of the hand in relation to the forearm.
www.medicalppt.blogspot.com only collects and share links from other websites ,"Everything under one umbrella " .We do not host or modify the presentations.These lecture notes are sole property of original uploaders. We are just sharing them for helping medical education world wide.If you find any copyrighted slides inform me i will take necessary actions.If any of of you have a good personal power point presentation Email me i will upload it here. ...
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These chewy, brown morsels are full of phytonutrients - plant-based compounds that deliver positive health effects. Numerous scientific studies have shown that shiitake phytonutrients can help regulate our immune system, improve our cardiovascular health, and protect us from cancer. Read on to learn more about these delicious and healthful shiitake mushrooms!. ...
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Eritadenine is a substance that might help the Western world to overcome one of the biggest cause of death, cardiovascular disease, by lowering the levels of cholesterol in blood by an accelerated excretion of ingested cholesterol. The aim of this thesis work was to elucidate if enzymatic pre-treatment of shiitake mushrooms increases the yield of the extraction process of the valuable substance eritadenine by increasing the degradation of the fungal cell walls. The enzymes used in this study, had glucanase and chitinase activity and was a gift from Novozymes, Denmark. The extraction process involves treatment with methanol followed by extraction with ether and finally ion exchange in order to obtain a sample as pure as possible for analysis. In contrast to previously used methods the mushrooms are treated with enzymes before the methanol extraction, which hopefully facilitate the degradation of the cell walls. The results obtained with enzymatic pre-treatment showed a deterioration compared to ...
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These days I almost always have a batch of kimchi going in the fridge and my latest batch was ready. I could not wait to to try it and I knew exactly what I wanted to make, a kimchi pizza. Kimchi generally comes with a lot of liquid so you often need to squeeze the excess off. When making some dishes such as the kimchi quesadillas you even need to think about removing some of the moisture from the fermented cabbage to make sure that you do not end up with a soggy quesadilla. With a pizza however, I figured that all of that flavour packed kimchi juice would make the perfect pizza sauce. Bacon goes so well with kimchi that I did not even think about making the kimchi pizza without it and you couldnt have a pizza without some cheese. I still wanted something else on the pizza and I thought that some shiitake mushrooms would do well. Since I had just cooked some bacon I lightly sauteed the mushrooms in the grease before adding to the pizza to get even more of that bacon flavour. After the pizza ...
Savor the rich, meaty flavor and delicate texture of homegrown shiitake mushrooms. Grow them indoors or outdoors with little effort and no mess using our hand-cut hardwood log, which is inoculated with spores that produce a crop of organic shiitak…
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5 good sized shiitake mushrooms, stems discarded, caps diced 1 onion, chopped 1 cup water 1 teaspoon vegan beef style broth mix 1 1/2 tablespoons soy sauce 1 tablespoon oyster sauce 1 1/2 tablespoons vegan margarine 2 1/2 tablespoons whole wheat flour
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Ingredients. 1-16 oz cake of organic traditional firm tofu, pressed and scrambled with a fork or pastry cutter. 2 to 3 tablespoons of Rich & Creamy MELT® Organic. 1 small onion, or ½ medium sized onion, chopped. 5 to 6 large leaves of collard greens, destemmed and chopped. 6 to 8 large shiitake mushrooms, stems removed and chopped. 3 to 4 tablespoons of vegan creamer or half and half. 1 teaspoon turmeric. 1 teaspoon salt. ¼ teaspoon pepper. Tamari to taste. Directions. Tofu preparation. ...
Braised Cod with Shiitake Mushrooms recipe. There is an ingredient listing, instructions on how to make it and a printer friendly version.
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Amiodarone has several potentially fatal toxicities. The most important of these is pulmonary toxicity (hypersensitivity pneumonitis or interstitial/alveolar pneumonitis). This has occurred as clinically manifest disease at rates as high as 17 percent in some series of patients with ventricular arrhythmias given doses of around 400 mg daily, as abnormal diffusion capacity without symptoms in a much higher percentage of patients. Pulmonary toxicity is fatal about 10 percent of the time. Hepatic injury is common with amiodarone, but is usually mild and evidenced only by abnormal liver enzymes. Overt liver disease can occur, however, and has been fatal in a few cases. Amiodarone can exacerbate the ventricular arrhythmia being treated by, for example, making the arrhythmia less well-tolerated or more difficult to reverse. This has occurred in approximately 2 to 5 percent of patients in various series, and significant heart block or sinus bradycardia has been seen in 2 to 5 percent of patients. ...
IgE-mediated reactions. Anecdotal evidence suggests that T. viride may induce symptoms of asthma and hypersensitivity pneumonitis (HP) in sensitised individuals. (17) However, few studies have been reported to date; it is possible that the allergy occurs more frequently than has been reported.. The closely related genus member T. citrinoviride may play a role in the aetiology of adult-onset asthma, or serve as an indicator of other causal factors. (18). A 54-year-old woman presented with dyspnoea, cough, chest pain, and fever. A diagnosis of HP was made by a combination of clinical, radiologic, physiologic, and immunologic studies. T. viride was isolated in cultures of water samples from an ultrasonic humidifier installed in the patients home a year earlier. Precipitating immunoglobulin G antibodies to T viride were detected in the patients serum by enzyme-linked immunosorbent assay. The patient remained symptom-free after the humidifier was removed from her home. (17). A 34-year-old sawmill ...
Mold Exposure and Health Risks. Exposure to damp and moldy environments may cause a variety of health effects. Some people are sensitive to molds. For these people, molds can cause nasal stuffiness, throat irritation, coughing or wheezing, eye irritation, or, in some cases, skin irritation. People with mold allergies may have more severe reactions. Immune-compromised people and people with chronic lung illnesses, such as obstructive lung disease, may get serious infections in their lungs when they are exposed to mold. In 2004 the Institute of Medicine (IOM) found there was sufficient evidence to link indoor exposure to mold with upper respiratory tract symptoms, cough, and wheeze in otherwise healthy people; with asthma symptoms in people with asthma; and with hypersensitivity pneumonitis in individuals susceptible to that immune-mediated condition.. Where is mold found in the home?. Mold is found both indoors and outdoors. Mold can enter your home through open doorways, windows, vents, and ...
The mission of the Johns Hopkins University Dermatology, Allergy and Clinical Immunology (DACI) Reference Laboratory is to provide comprehensive, high-quality diagnostic allergy and immunology testing to patients throughout North America with asthma, allergy and immunologic disorders. We offer an extensive menu of laboratory tests that includes allergen-specific IgE measurements to approximately 300 pollen, epidermal, mold spore, mite, food, drug, venom and occupational allergen specificities. We specialize in Hymenoptera (insect sting) venom-specific IgE and IgG antibody measurements. In addition, the DACI Laboratory performs hypersensitivity pneumonitis precipitin panels, serum cotinine, and environmental mold measurements.. Research Areas: immunology, asthma, allergies, allergens, dermatology ...
Background. Fungal antigens sensibilization is a known cause of hypersensitivity pneumonitis (HP). Nevertheless, the role of fungal colonization in respiratory tract on clinics and prognosis of HP is still unclear.. Aim. To assess the influense of fungal colonization on excercise tolerance in HP.. Methods. 79 pts with morphologically proven HP were enrolled. Mean age 48,8 yrs, males 33. In all cases during work-up BAL was performed with PCR test on DNA of Aspergillus and Candida fungi, as also as PFT and 6MWT. Data were analyzed using Mann-Whitney test.. Results. Fungi were detected in 21/79 (27%) pts. The were no difference between PCR-positive and negative groups for Aspergillus in PFT, but there was significant difference for sPO2 before and after 6MWT (94,1 and 90 %; 91 and 88% respectively, p,0.05), as also as more prominent fatigue on Borg scale (2,9 and 3,9; 5,3 and 6,5 points, respectively p,0.05). There was a trend to lower walking distance in PCR-positive patients vs controls (380 and ...
If you find out that toxigenic molds are growing in such areas in your home and you need great effective treatments, you are also free to contact a mold removal expert immediately. These molds not only harm and irritate different allergy sufferers, but also result in hypersensitivity pneumonitis, blindness, irreversible brain damage, and pushing the growth of cancer in human body.. What aids in the growth of molds?. The most important thing that molds need to trigger their growth is water. As this fungus decomposes dead organic material like cellulose, hemi-cellulose and lignin, it has the ability to develop on wood and paper. The digestive fluids secreted by molds decompose the substrate, thus making the nutrients available for them. Additionally, this fungus is also capable to digest some synthetic supplies such as adhesives, pastes as well as paints. Molds can also grow on the organic dirt/dust layer present on the surfaces of concrete, plastic, glass and metal. When the comparative humidity ...
The FDA is alerting consumers about "potentially life-threatening health problems" linked to Limbrel, a dietary supplement that is marketed to "manage the metabolic processes associated with osteoarthritis." The company is not removing the product from the market. This product is marketed as a medical food, but the FDAs investigation determined that it is an unapproved new drug. And the FDA does not have mandatory recall authority over drug products.. The FDA is reminding consumers "not to use Limbrel because of the risk of drug-induced liver injury, and a lung condition called hypersensitivity pneumonitis. Consumers taking this product should stop immediately and contact their health care provider. Health care providers who are aware that their patients are taking Limbrel should advise them to stop using it." Limbrel is available in capsule form in two dosages: Limbrel250 and Limbrel500.. Public health officials are investigating a rise in reports of serious adverse events involving the ...
When microwaving, use a large- or tall-enough container and add water to the shiitake height, and start with 30-60 seconds. Repeat as necessary. Check frequently, as the water tends to boil over. Dilute the liquid as necessary when using it as dashi stock ...
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Its up to you to teach your Havanese puppy what is appropriate to chew and what isnt. This article covers some helpful hints to get you headed in the right direction.
This recipe is from a vegetarian print-maker I used to work with. Add as much spinach and mushrooms as you like. Remember they will wilt/shrink down. I love them both so I will tend to add a little more. I hope you like it as much as I do.
Cook beans in large pot of boiling water until tender but still bright green, about 5 minutes. Drain. Rinse beans in very cold water, drain again and set aside ...
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A simple slaw is given an Asian twist with bok choy, napa cabbage and a soy-wasabi dressing. The vibrant flavors and rich textures make this a great introduction to tofu for novices and skeptics.
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Fermented black beans add a unique umami flavor and saltiness to this vegan version of the traditional Hunan dish Home-style Tofu.
22,000 becquerels measured in workers lungs Sources at Japans science ministry have told NHK that up to 22,000 becquerels of radioactivity have been detected in the lungs of a worker accidentally exposed to radioactive materials at a nuclear research facility. The worker is one of 5 who were exposed to the contaminants on Tuesday at…
Learn about the veterinary topic of Diffuse Fibrosing Alveolitis in Cattle. Find specific details on this topic and related topics from the Merck Vet Manual.
Amylase An enzyme that is found in saliva and pancreatic secretions (see pancreas). Amylase helps the body to digest dietary starch, breaking it down into smaller components, such as the sugars glucose and maltose. Amsler chart A diagnostic tool used by ophthalmologists to detect changes in the retina, particularly those changes that indicate macular degeneration. A typical Amsler chart consists of a grid of black lines on a white background. In an individual with retinal changes, the lines may appear distorted. CAUSES Alveolitis is commonly caused by an allergic reaction to inhaled dust of animal or plant origin, as in farmers lung (caused by spores from mouldy hay), bagassosis (caused by spores from mouldy sugar-cane residue), and pigeon fanciers lung (caused by particles from bird droppings). This type of alveolitis is known as extrinsic allergic alveolitis. alprostadil A prostaglandin drug used to minimize the effects of congenital (present from birth) heart defects in newborn babies prior ...
Adaptogenic Liver Support The shiitake mushroom is revered throughout Asia as a tonifying mushroom. It is used both as a food and for its health promoting benefits. Shiitake Mushroom Supreme combines the world-renowned Lentinus edodes Mycelia Extract (LEM) form of shiitake with reishi mushroom, and with liver-supporting herbs such as milk thistle, turmeric, schisandra and ligustrum. The result: a supreme shiitake adaptogenic formula, specially designed to support a healthy liver. Shiitake: Prized Adaptogen Shiitake mushroom, one of the most highly prized botanicals of Chinese and Japanese herbalism, is the centerpiece of Shiitake Mushroom Supreme. Traditionally shiitake was used to improve circulation and vigor and to support a wide range of body systems. Today shiitake is valued for its delicious taste and as an adaptogen, and is the number one agricultural export of Japan. Adaptogens are defined as substances that enhance general adaptive response. They increase resistance against external
China Lentinula Edodes (Shiitake) (F1004), Find details about China Shiitake, Shiitake Mushroom from Lentinula Edodes (Shiitake) (F1004) - Shanghai Finc Food Co., Ltd.
An important notice on our inventory and shipping of mushroom logs: Knox County Tennessee (our home sweet home) is currently under a hardwood firewood export ban as the result of Emerald Ash Borer infestation in East Tennessee. The regulation restricts the movement of firewood of all hardwood (non-coniferous) species. Our logs are harvested fresh, plugged quickly, and stored in our protected demonstration garden, and we believe them to be unaffected by the EAB. Although our logs are not firewood and are not exposed to firewood lots, we still feel it is responsible for us to abide by this movement restriction. Therefore, for the foreseeable future, mushroom logs will not be available for shipping. Although this page lists the product as sold out, we still maintain a stock of this product at our demonstration garden and showroom in Knoxville. Customers are more than welcome to stop by for local pickup and purchase.. Now for more on mushroom logs.... Folks have been growing shiitake mushrooms from ...
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BACKGROUND:. Although many investigations have been conducted to characterize the pathogenesis of interstitial lung diseases, few examined the epidemiology of these disorders in a general population. The establishment of the registry represented the first step in a sequence of investigations designed to characterize the epidemiology of the interstitial lung diseases. The registry initially served a descriptive purpose; the incidence of the interstitial lung diseases was measured in a defined population. Subsequently the registry served as a mechanism for ascertaining cases for a case-control study. Finally, the registry provided population-based data for clinical purposes on presentation, physiology, and natural history of the interstitial lung diseases.. DESIGN NARRATIVE:. The resources of the New Mexico Tumor Registry were adapted to identify new cases of interstitial lung disease in Bernalillo County. Other sources of information for identifying new cases included pulmonary physicians, ...
TY - JOUR. T1 - Significance of granulomatous inflammation in usual interstitial pneumonia. AU - Tomic, R.. AU - Kim, H. J.. AU - Bors, M.. AU - Allen, T.. AU - Ritter, J.. AU - Dincer, E. H.. AU - Perlman, D. M.. AU - Bhargava, M.. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Sarcoidosis is a systemic granulomatous disease of unclear etiology with characteristic pulmonary lesions. We describe 2 unique cases of sarcoidosis where after approximately 20 years of clinical quiescence, patients developed interstitial opacities on chest CT scan and an increase in shortness of breath. With lack of therapeutic response to a course of prednisone, both patients underwent a surgical lung biopsy that revealed a pattern consistent with Usual Interstitial Pneumonia (UIP) with honeycombing and fibroblastic foci. Postoperatively, the course of the disease was consistent with what would be expected in Idiopathic Pulmonary Fibrosis. Ultimately the disease progressed with one patient needed lung transplantation and the ...

Extrinsic Allergic Alveolitis | Encyclopedia.comExtrinsic Allergic Alveolitis | Encyclopedia.com

It also is known as "extrinsic" allergic alveolitis, meaning that the antigen that sets up the allergic reaction (also called ... "allergic alveolitis." "Allergic" refers to the antigen-antibody reaction, and "alveolitis" means an inflammation of the tiny ... Hypersensitivity pneumonitis, also called extrinsic allergic alveolitis, is an inflammatory condition of the lung caused by the ... A number of different types of HP are known, since a wide range of allergens may produce an allergic reaction in the lungs. ...
more infohttps://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/extrinsic-allergic-alveolitis

Extrinsic Allergic Alveolitis Imaging: Overview, Radiography, Computed TomographyExtrinsic Allergic Alveolitis Imaging: Overview, Radiography, Computed Tomography

Extrinsic allergic alveolitis, or hypersensitivity pneumonitis, was first described in Iceland in 1874. Radiographic and ... encoded search term (Extrinsic Allergic Alveolitis Imaging) and Extrinsic Allergic Alveolitis Imaging What to Read Next on ... Extrinsic Allergic Alveolitis Imaging. Updated: Nov 16, 2015 * Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: ... Extrinsic allergic alveolitis, or hypersensitivity pneumonitis, was first described in Iceland in 1874. Radiographic and ...
more infohttps://emedicine.medscape.com/article/356120-overview

Extrinsic allergic alveolitisExtrinsic allergic alveolitis

... Subscriber Sign In VisualDx Mobile Feedback Select Language Share Enter a Symptom, Medication, ... Extrinsic allergic alveolitis Print Images (21) Contributors: Mary Anne Morgan MD, Ryan R. Walsh MD, Joshua J. Jarvis MD, ...
more infohttps://www.visualdx.com/visualdx/diagnosis/extrinsic+allergic+alveolitis?diagnosisId=55151&moduleId=101

Extrinsic allergic alveolitisExtrinsic allergic alveolitis

... Subscriber Sign In VisualDx Mobile Feedback Select Language Share Enter a Symptom, Medication, ... Extrinsic allergic alveolitis Print Images (21) Contributors: Mary Anne Morgan MD, Ryan R. Walsh MD, Joshua J. Jarvis MD, ...
more infohttps://www.visualdx.com/visualdx/diagnosis/extrinsic+allergic+alveolitis?moduleId=101&diagnosisId=55151

What is included in patient education about mold-related extrinsic allergic alveolitis (EAA)?What is included in patient education about mold-related extrinsic allergic alveolitis (EAA)?

... Updated: Sep 18, 2017 ... encoded search term (What is included in patient education about mold-related extrinsic allergic alveolitis (EAA)?) and What is ... included in patient education about mold-related extrinsic allergic alveolitis (EAA)? What to Read Next on Medscape. Related ... Allergic bronchopulmonary aspergillosis. Middleton E, Reed CE, Ellis EF, et al. Allergy: Principles and Practice. 4th ed. Mosby ...
more infohttps://www.medscape.com/answers/887374-175528/995056-overview

Alveolitis, extrinsic allergic | definition of Alveolitis, extrinsic allergic by Medical dictionaryAlveolitis, extrinsic allergic | definition of Alveolitis, extrinsic allergic by Medical dictionary

What is Alveolitis, extrinsic allergic? Meaning of Alveolitis, extrinsic allergic medical term. What does Alveolitis, extrinsic ... extrinsic allergic in the Medical Dictionary? Alveolitis, extrinsic allergic explanation free. ... Alveolitis, extrinsic allergic , definition of Alveolitis, extrinsic allergic by Medical dictionary https://medical-dictionary. ... It also is known as extrinsic allergic alveolitis, meaning that the antigen that sets up the allergic reaction (also called ...
more infohttps://medical-dictionary.thefreedictionary.com/Alveolitis%2C+extrinsic+allergic

Hypersensitivity pneumonitis (extrinsic allergic alveolitis) | Primum non nocereHypersensitivity pneumonitis (extrinsic allergic alveolitis) | Primum non nocere

Hypersensitivity pneumonitis (extrinsic allergic alveolitis). Hypersensitivity pneumonitis is a condition where the lungs ... a lymphocytic alveolitis on bronchoalveolar lavage (BAL), and/or a granulomatous reaction on lung biopsies. ...
more infohttps://gardenrain.wordpress.com/2009/04/20/hypersensitivity-pneumonitis-extrinsic-allergic-alveolitis/

Natural cure for Alveolitis, extrinsic allergic and alternative treatmentsNatural cure for Alveolitis, extrinsic allergic and alternative treatments

... extrinsic allergic that can make a difference in your life or the life of someone you love with alternative treatments. ... Alveolitis, extrinsic allergic by state. Alveolitis, extrinsic allergic in Alabama. Alveolitis, extrinsic allergic in Alaska. ... Alveolitis, extrinsic allergic in Iowa. Alveolitis, extrinsic allergic in Kansas. Alveolitis, extrinsic allergic in Kentucky. ... Alveolitis, extrinsic allergic natural cures. Alveolitis, extrinsic allergic Definition. Extrinsic allergic alveolitis (EAA), ...
more infohttp://www.naturalcurefor.com/treatments/alveolitis-extrinsic-allergic

Occupational Asthma Reference: Extrinsic allergic alveolitis caused by a cold water humidifier, Thorax, 1987; 42: 32-37Occupational Asthma Reference: Extrinsic allergic alveolitis caused by a cold water humidifier, Thorax, 1987; 42: 32-37

Robertson AS, Burge PS, Wieland GA, Carmalt MH, Extrinsic allergic alveolitis caused by a cold water humidifier, Thorax, 1987; ... Three workers developed classical extrinsic allergic alveolitis while working in a printing works that had a contaminated cold ... and lung biopsy specimens that showed an alveolitis with giant cells and cholesterol clefts. In two subjects bronchoalveolar ...
more infohttp://occupationalasthma.com/occupational_asthma_viewreference.aspx?id=2926

Bronchoalveolar lavage cell profiles and proteins concentrations can be used to phenotype extrinsic allergic alveolitis...Bronchoalveolar lavage cell profiles and proteins concentrations can be used to phenotype extrinsic allergic alveolitis...

Extrinsic allergic alveolitis (EAA) patients form heterogenous group with different clinical manifestation and different ... Extrinsic allergic alveolitis (EAA) continue to attract the interest of medical doctors and scientists because of the lack of ... a, b, c, d Extrinsic allergic alveolitis - correlations between BALF protein concentrations, DLco, FVC and BALF cell ... Extrinsic allergic alveolitis (EAA) patients form heterogenous group with different clinical manifestation and different ...
more infohttps://mrmjournal.biomedcentral.com/articles/10.1186/s40248-019-0175-6

Overview of Disease Flashcards by Katrina Campbell | BrainscapeOverview of Disease Flashcards by Katrina Campbell | Brainscape

Extrinsic Allergic Alveolitis. Hypersensitivity Penumonitis Type 3 reaction. Farmers Lung - mouldy hay, granulomatous ...
more infohttps://www.brainscape.com/flashcards/overview-of-disease-5546323/packs/8342332

Alasdair Scotts notes Flashcards by Scott Godfrey | BrainscapeAlasdair Scott's notes Flashcards by Scott Godfrey | Brainscape

Extrinsic allergic alveolitis. Def. Ax. Px Def. Acute allergen exposure in sensitised pts. T3HS Chronic exposure = granuloma ...
more infohttps://www.brainscape.com/flashcards/alasdair-scott-s-notes-6572377/packs/10368755

Mold Allergy Differential DiagnosesMold Allergy Differential Diagnoses

Extrinsic allergic alveolitis Individuals who are exposed to mycotoxin in an atmosphere with molds may develop symptoms of ... Allergic bronchopulmonary aspergillosis. Middleton E, Reed CE, Ellis EF, et al. Allergy: Principles and Practice. 4th ed. Mosby ... Allergic aspergillosis: a newly recognized form of sinusitis in the pediatric population. Laryngoscope. 1989 Jul. 99(7 Pt 1): ... Fungal levels in the home and allergic rhinitis by 5 years of age. Environ Health Perspect. 2005 Oct. 113(10):1405-9. [Medline] ...
more infohttps://emedicine.medscape.com/article/887374-differential

Small Airway Involvement in Patients With Chronic Hypersensitivity Pneumonitis - Full Text View - ClinicalTrials.govSmall Airway Involvement in Patients With Chronic Hypersensitivity Pneumonitis - Full Text View - ClinicalTrials.gov

Alveolitis, Extrinsic Allergic. Hypersensitivity. Immune System Diseases. Lung Diseases. Respiratory Tract Diseases. ...
more infohttps://clinicaltrials.gov/ct2/show/NCT02523833

Dail and Hammars Pulmonary Pathology | SpringerLinkDail and Hammar's Pulmonary Pathology | SpringerLink

Hypersensitivity Pneumonitis (Extrinsic Allergic Alveolitis) Roberto Barrios. Pages 650-667 * Sarcoidosis Carol F. Farver ...
more infohttps://link.springer.com/book/10.1007%2F978-0-387-68792-6

Clubbing and Dacryoadenitis - Symptom Checker - check medical symptoms at RightDiagnosisClubbing and Dacryoadenitis - Symptom Checker - check medical symptoms at RightDiagnosis

6. Alveolitis, extrinsic allergic. 7. Aminopterin -- Teratogenic Agent. 8. Amobarbital -- Teratogenic Agent. 9. Amoxicillin -- ...
more infohttps://wrongdiagnosis.com/cosymptoms/clubbing/dacryoadenitis.htm

Clinical investigation of an outbreak of alveolitis and asthma in a car engine manufacturing plant | ThoraxClinical investigation of an outbreak of alveolitis and asthma in a car engine manufacturing plant | Thorax

extrinsic allergic alveolitis. FEV1. forced expiratory volume in 1 s. FVC. forced vital capacity. HF. humidifier fever. MWF. ... Extrinsic allergic alveolitis, Report by the Industrial Injuries Council in accordance with Section 171 of the Social Security ... Background: Exposure to metal working fluid (MWF) has been associated with outbreaks of extrinsic allergic alveolitis (EAA) in ... Table 4 Numbers with work-related respiratory disease according to case definitions for extrinsic allergic alveolitis (EAA), ...
more infohttp://thorax.bmj.com/content/62/11/981

Plus itPlus it

Baur X. Hypersensitivity pneumonitis (extrinsic allergic alveolitis) induced by isocyanates. J Allergy Clin Immunol 1995;95: ...
more infohttp://erj.ersjournals.com/content/32/3/807

A to Z: PneumonitisA to Z: Pneumonitis

May also be called: Hypersensitivity Pneumonitis; HP; Extrinsic Allergic Alveolitis; Bird Fanciers Lung; Farmers Lung; Hot ...
more infohttps://www.rchsd.org/health-articles/a-to-z-pneumonitis/

Wiley: Medicine at a Glance, 3rd Edition - Patrick DaveyWiley: Medicine at a Glance, 3rd Edition - Patrick Davey

109 Extrinsic allergic alveolitis (hypersensitivity pneumonitis) 220. 110 Pulmonary fibrosis 222. 111 Pulmonary eosinophilia ...
more infohttp://www.wiley.com/WileyCDA/WileyTitle/productCd-1118374002.html

Hypersensitivity - Fibromyalgia Message Board - HealthBoardsHypersensitivity - Fibromyalgia Message Board - HealthBoards

Extrinsic allergic alveolitis / hypersensitivity pneumonitis mom2katie. Lung & Respiratory Disorders / COPD. 7. 07-29-2003 08: ...
more infohttps://www.healthboards.com/boards/fibromyalgia/765007-hypersensitivity.html

Systematic assessment of difficult-to-treat asthma | European Respiratory SocietySystematic assessment of difficult-to-treat asthma | European Respiratory Society

... one had consolidation suggestive of extrinsic allergic alveolitis, one changes consistent with obliterative bronchiolitis and ... Patients were specifically asked about allergic triggers for asthma symptoms and the presence of allergic rhinitis. In addition ... Bousquet J, Van Cauwenberge P. Allergic rhinitis and its impact on asthma (ARIA). J Allergy Clin Immunol 2001;108:S1-S147. ... Fireman P. Rhinitis and asthma connection: management of coexisting upper airway allergic diseases and asthma. Allergy Asthma ...
more infohttps://erj.ersjournals.com/content/22/3/478?ijkey=63234c71d2d7e18874f0fd95f67f5ffdca5b772d&keytype2=tf_ipsecsha
  • One out of 3 preschool children and 2 out of 3 school children with recurrent wheezing/coughing are allergic . (wikipedia.org)
  • Describes and comments on 2 cases of extrinsic allergic alveolitis of occupational origin due to contact with domestic fowl (pigeons, chickens) and wet hay, respectively. (ilo.org)