Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.
The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth.
Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
The constricted part of the tooth at the junction of the crown and root or roots. It is often referred to as the cementoenamel junction (CEJ), the line at which the cementum covering the root of a tooth and the enamel of the tooth meet. (Jablonski, Dictionary of Dentistry, 1992, p530, p433)
Infections with bacteria of the family BACTEROIDACEAE.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Bone loss due to osteoclastic activity.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).
The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.
Technique involving the passage of X-rays through oral structures to create a film record while a central tab or wing of dental X-ray film is being held between upper and lower teeth.
Photographic techniques used in ORTHODONTICS; DENTAL ESTHETICS; and patient education.
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
A hollow part of the alveolar process of the MAXILLA or MANDIBLE where each tooth fits and is attached via the periodontal ligament.
Infections with bacteria of the genus ACTINOBACILLUS.
A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.
An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.
Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.
One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.
Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.
Conservative contouring of the alveolar process, in preparation for immediate or future denture construction. (Dorland, 28th ed)
Oral tissue surrounding and attached to TEETH.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.
Application of a ligature to tie a vessel or strangulate a part.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.
Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.
Orthodontic techniques used to correct the malposition of a single tooth.
Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
The emergence of a tooth from within its follicle in the ALVEOLAR PROCESS of the MAXILLA or MANDIBLE into the ORAL CAVITY. (Boucher's Clinical Dental Terminology, 4th ed)
The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821)
A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.
The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992)
The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.
X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.
Extracellular substance of bone tissue consisting of COLLAGEN fibers, ground substance, and inorganic crystalline minerals and salts.
The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
Surgical procedure to add bone to the ALVEOLAR RIDGE in children born with a CLEFT LIP and a CLEFT PALATE.
The process of bone formation. Histogenesis of bone including ossification.
The grafting of bone from a donor site to a recipient site.
Diseases of BONES.
Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.
Tumors or cancer located in bone tissue or specific BONES.
One of a set of bone-like structures in the mouth used for biting and chewing.
The surgical removal of a tooth. (Dorland, 28th ed)
Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.
Radiographic techniques used in dentistry.
The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)
Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.
Horizontal and, to a lesser degree, axial movement of a tooth in response to normal forces, as in occlusion. It refers also to the movability of a tooth resulting from loss of all or a portion of its attachment and supportive apparatus, as seen in periodontitis, occlusal trauma, and periodontosis. (From Jablonski, Dictionary of Dentistry, 1992, p507 & Boucher's Clinical Dental Terminology, 4th ed, p313)
Elements of limited time intervals, contributing to particular results or situations.
Biocompatible materials placed into (endosseous) or onto (subperiosteal) the jawbone to support a crown, bridge, or artificial tooth, or to stabilize a diseased tooth.
A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.
The longest and largest bone of the skeleton, it is situated between the hip and the knee.

Morphological changes in periodontal mechanoreceptors of mouse maxillary incisors after the experimental induction of anterior crossbite: a light and electron microscopic observation using immunohistochemistry for PGP 9.5. (1/419)

Ruffini nerve endings (mechanoreceptors) in the periodontal ligament (PDL) of mouse incisors were examined to elucidate whether experimentally-induced crossbites cause any changes or abnormalities in their morphology and distribution. Anterior guiding planes were attached to the mandibular incisors of 3-week-old C3H/HeSlc mice. At 3 days and 1, 2, 4, 6, and 8 weeks post-attachment of the appliance, the mice were sacrificed by perfusion fixation. Frozen sagittal cryostat sections of the decalcified maxillary incisors were processed for immunohistochemistry of protein gene product 9.5, followed by histochemical determination of tartrate-resistant acid phosphatase activity to reveal sites of alveolar bone resorption. Despite the absence of bone resorption within the lingual PDL of control mice, distinct resorption sites were seen in the respective regions of the experimental animals. Unlike the controls, many Ruffini endings showing vague and swollen contours, with unusually long and pedunculated micro-projections were observed in the affected lingual PDL of the incisors in the experimental animals with short-term anterior crossbite induction. Club-shaped nerve terminations with few, if any, micro-projections were observed in the lingual PDL of experimental animals with long-term induction, as well as in aged control mouse incisors. Differences in the distribution of Ruffini endings were also observed. These results indicate that changing the direction of the force applied to the PDL results in rapid and prolonged changes in the morphology of Ruffini-like mechanoreceptors.  (+info)

Histological and histochemical quantification of root resorption incident to the application of intrusive force to rat molars. (2/419)

This study was conducted to investigate the nature of root resorption resulting from intrusive forces applied to the rat lower molars, by means of histological and histochemical techniques with tartrate resistant acid phosphatase (TRAP). Thirty-eight 13-week-old Wistar strain male rats were used. Intrusive force was created by a fixed appliance which was adjusted to exert an initial force of 50 g for the duration of 1, 2, and 3 weeks. The degree of root resorption and distribution of TRAP positive cells were evaluated. On the root surface, the TRAP positive scores were low in the apical regions. Significant differences in the scores were found in the inter-radicular region of the roots between the experimental and control groups for the 2- and 3-week groups. More active resorption of bone occurred during the experimental period, as denoted by greater TRAP positive scores on the bone than on the root surface. Root resorption scores in the apical root region were larger in the 2- and 3-week groups than in the 1-week group. Significant differences in the root resorption scores were also found between the 1- and 3-week groups in the inter-radicular region, indicating that intrusive force application of a longer duration may lead to a higher frequency of root resorption. It is shown that, irrespective of the level of TRAP positive cells and root resorption scores, the degree of root resorption activity is higher in the apical root region than in the inter-radicular area. These results indicate that cellular cementum may be resorbed more easily because of its richer organic components and low mineralized structure.  (+info)

Host modulation as a therapeutic strategy in the treatment of periodontal disease. (3/419)

Specific microorganisms initiate the immunoinflammatory processes that destroy tissue in periodontitis. Recent work has demonstrated, in addition to bacterial control, that modulation of the host immunoinflammatory response is also capable of controlling periodontitis. Matrix metalloproteinases (MMPs) destroy collagen and other matrix components, and the osteoclastic bone remodeling determines the periodontal bone response to a bacterial challenge. Other components of the biology, including cytokines and prostanoids, regulate MMPs and bone remodeling and are also involved in regulating the production of defensive elements, such as antibody. Agents directed at blocking MMPs or osteoclastic activity are effective in reducing periodontitis. Agents that inhibit prostaglandin E2 and selective blockage of specific cytokines have also been effective. Improved knowledge of bacterium-host interactions and of the processes leading to tissue destruction will help to identify targets for host modulation to reduce periodontitis in selected situations.  (+info)

CD4(+) T cells and the proinflammatory cytokines gamma interferon and interleukin-6 contribute to alveolar bone loss in mice. (4/419)

In this study, we used a mouse model to examine the role of the adaptive immune response in alveolar bone loss induced by oral infection with the human gram-negative anaerobic bacterium Porphyromonas gingivalis. Severe combined immunodeficient mice, which lack B and T lymphocytes, exhibited considerably less bone loss than did immunocompetent mice after oral infection, suggesting that lymphocytes contribute to this process. Bone loss after oral infection was decreased in mice deficient in major histocompatibility complex (MHC) class II-responsive CD4(+) T cells, but no change in bone loss was observed in mice deficient in MHC class I-responsive CD8(+) T cells or NK1(+) T cells. Mice lacking the cytokine gamma interferon or interleukin-6 also demonstrated decreased bone loss. These results suggest that the adaptive immune response, and in particular CD4(+) T cells and the proinflammatory cytokines that they secrete, are important effectors of bone loss consequent to P. gingivalis oral infection. The studies also reinforce the utility of the mouse oral infection model in dissecting the pathobiology of periodontal disease.  (+info)

C-telopeptide pyridinoline cross-links. Sensitive indicators of periodontal tissue destruction. (5/419)

C-telopeptides and related pyridinoline cross-links of bone Type I collagen are sensitive markers of bone resorption in osteolytic diseases such as osteoporosis and osteoarthritis. We have studied the release of C-telopeptide pyridinoline crosslinks of Type I collagen as measures of bone destruction in periodontal disease. Studies in preclinical animal models and humans have demonstrated the relationship between radiographic bone loss and crevicular fluid C-telopeptide levels. We have recently found that C-telopeptide levels correlate strongly with microbial pathogens associated with periodontitis and around endosseous dental implants. Host-modulation of bone-related collagen breakdown has been shown by studies in humans demonstrating that MMP inhibition blocks tissue destruction and release of C-telopeptides in patients with active periodontal disease.  (+info)

Host responses to recombinant hemagglutinin B of Porphyromonas gingivalis in an experimental rat model. (6/419)

Porphyromonas gingivalis, a gram-negative, black-pigmented anaerobe, is among the microorganisms implicated in the etiology of adult periodontal disease. This bacterium possesses a number of factors, including hemagglutinins, of potential importance in virulence. Several hemagglutinin genes have been identified, cloned, and expressed in Escherichia coli. The purpose of this study was to characterize host responses to purified recombinant hemagglutinin B (rHag B), using the conventional Fischer rat as the experimental animal model. The effectiveness of immunization with rHag B on protection against experimental periodontal bone loss following infection with P. gingivalis was also evaluated. Groups of rats were immunized by the subcutaneous route with rHag B in complete Freund's adjuvant, immunized with rHag B and orally infected with P. gingivalis, nonimmunized and noninfected, or orally infected with P. gingivalis only. Serum and saliva samples were collected throughout the experiment and evaluated for serum immunoglobulin G (IgG) and IgM and salivary IgA antibody activity by enzyme-linked immunosorbent assay. No salivary IgA anti-Hag B activity was detected in the various groups of rats. A slight serum IgM response similar to that seen in preimmune samples was observed. Serum IgG antibody activity to Hag B was detected only in samples from rats immunized with rHag B. This response was primarily of the IgG1 and IgG2a subclasses, followed by IgG2b and low levels of IgG2c. Supernatants from rHag B-stimulated splenic lymphoid cell cultures from immunized rats contained high levels of gamma interferon, followed by interleukin-2 (IL-2), IL-10, and then IL-4. These results are consistent with the induction of T helper type 1 (Th1)- and Th2-like responses. Western blot analysis of sera derived from rHag B-immunized rats reacted with trichloroacetic acid (TCA) precipitates of P. gingivalis 33277, 381, A7A1-28, and W50, revealing a 50-kDa band reflective of Hag B. However, sera derived from rats immunized with P. gingivalis whole cells or from rats infected with P. gingivalis only did not react with rHag B but did react with TCA precipitates of P. gingivalis strains. Finally, radiographic measurements of periodontal bone loss indicated that rats immunized with rHag B had less bone loss than those infected with P. gingivalis only. These results demonstrate the effectiveness of purified rHag B in inducing a protective immune response and support the potential usefulness of this component of P. gingivalis in the development of a vaccine against adult periodontitis.  (+info)

Requirement of B7 costimulation for Th1-mediated inflammatory bone resorption in experimental periodontal disease. (7/419)

The CD28 costimulation at TCR signaling plays a pivotal role in the regulation of the T cell response. To elucidate the role of T cells in periodontal disease, a system of cell transfer with TCR/CD28-dependent Th1 or Th2 clones was developed in rats. Gingival injection of specific Ag, Actinobacillus actinomycetemcomitans 29-kDa outer membrane protein, and LPS could induce local bone resorption 10 days after the transfer of Ag-specific Th1 clone cells, but not after transfer of Th2 clone cells. Interestingly, the presence of LPS was required not only for the induction of bone resorption but also for Ag-specific IgG2a production. LPS injection elicited the induction of expression of both B7-1 and B7-2 expression on gingival macrophages, which otherwise expressed only MHC class II when animals were injected with Ag alone. The expression of B7 molecules was observed for up to 3 days, which corresponded to the duration of retention of T clone cells in gingival tissues. Either local or systemic administration of CTLA4Ig, a functional antagonist of CD28 binding to B7, could abrogate the bone resorption induced by Th1 clone cells combined with gingival challenge with both Ag and LPS. These results suggest that local Ag-specific activation of Th1-type T cells by B7 costimulation appeared to trigger inflammatory bone resorption, whereas inhibition of B7 expression by CTLA4Ig might be a therapeutic approach for intervention with inflammatory bone resorption.  (+info)

Long-term follow-up of maxillary incisors with severe apical root resorption. (8/419)

The purpose of the study was to analyse the mobility of teeth with severe orthodontically induced root resorption, at follow-up several years after active treatment, and to evaluate mobility in relation to root length and alveolar bone support. Seventy-three maxillary incisors were examined in 20 patients, 10-15 years after active treatment in 13 patients (age 24-32 years) and 5-10 years after active treatment in seven patients (age 20-25 years). All had worn fixed or removable retainers; seven still had bonded twistflex retainers. Total root length and intra-alveolar root length were measured on intra-oral radiographs. Tooth mobility was assessed clinically according to Miller's Index (0-4) and the Periotest method. Crestal alveolar bone level, periodontal pocket depth, gingival, and plaque indices, occlusal contacts during occlusion and function, and dental wear were recorded. There was a significant correlation (P < 0.05) between tooth mobility, and total root length and intra-alveolar root length. No correlation was found between tooth mobility and retention with twistflex retainers. None of the variables for assessment of periodontal status, occlusion and function were related to total root length or tooth mobility. It is concluded that there is a risk of tooth mobility in a maxillary incisor that undergoes severe root resorption during orthodontic treatment, if the remaining total root length is < or = 9 mm. The risk is less if the remaining root length is > 9 mm. Follow-up of teeth with severe orthodontically induced root resorption is indicated.  (+info)

TY - JOUR. T1 - Effect of an aldose reductase inhibitor on alveolar bone loss associated with periodontitis in diabetic rats. AU - Kador, Peter F.. AU - Hamada, Tomofumi. AU - Reinhardt, Richard A.. AU - Blessing, Karen. PY - 2010/5/1. Y1 - 2010/5/1. N2 - Periodontitis is a lesser known but frequent complication of diabetes mellitus and is the major cause of tooth loss in patients with diabetes. Dental therapy for this complication is primarily focused on the control of oral infections. No current therapy directly addresses the potential effects of diabetes itself on this complication. In studies conducted in young normal control and streptozotocin diabetic rats (100 g) treated with and without the aldose reductase inhibitor (ARI) imirestat, experimental periodontitis was induced in one side of the mouth by 3 injections of lipopolysaccharide (LPS) from Escherichia coli 055:B5 9 into the palatal gingiva between the first and second maxillary molars at 48-hour intervals. The other control side was ...
BACKGROUND AND OBJECTIVES: Strontium ranelate is a medication indicated for the treatment of osteoporosis that presents concomitant anti-resorptive and osteoanabolic dual biological activity. However, the effects of strontium ranelate on alveolar bone have been poorly explored. Furthermore, to date, there are no data on the effects of this medication on alveolar bone loss (BL) during conditions of estrogen deficiency. Therefore, the aim of this study was to evaluate the effects of strontium ranelate on ligature-induced periodontitis in estrogen-deficient and estrogen-sufficient rats. METHODS: Ninety-six rats were assigned to one of the following groups: sham-surgery + water (estrogen-sufficient; n = 24); ovariectomy + water (estrogen-deficient; n = 24), sham-surgery + strontium ranelate (ranelate/estrogen-sufficient; n = 24) and; ovariectomy + strontium ranelate (ranelate/estrogen-deficient; n = 24). The rats received strontium ranelate or water from the 14th day after ovariectomy until the end ...
Objective: In this study we have assessed the renal and cardiac consequences of ligature-induced periodontitis in both normotensive and nitric oxide (NO)-deficient (L-NAME-treated) hypertensive rats.Materials and methods: Oral L-NAME (or water) treatment was started two weeks prior to induction of periodontitis. Rats were sacrificed 3, 7 or 14 days after ligature placement, and alveolar bone loss was evaluated radiographically. Thiobarbituric reactive species (TBARS; a lipid peroxidation index), protein nitrotyrosine (NT; a marker of protein nitration) and myeloperoxidase activity (MPO; a neutrophil marker) were determined in the heart and kidney.Results: In NO-deficient hypertensive rats, periodontitis-induced alveolar bone loss was significantly diminished. In addition, periodontitis-induced cardiac NT elevation was completely prevented by L-NAME treatment. on the other hand L-NAME treatment enhanced MPO production in both heart and kidneys of rats with periodontitis. No changes due to ...
DR could be a supplementary medicine for periodontal therapy as it could reduce bone resorption in rat model of alveolar bone resorption and exert osteogenic effect on osteoblasts.
Journal of Shahid Sadoughi University of Medical Sciences ماهنامه علمی پژوهشی دانشگاه علوم پزشکی و خدمات بهداشتی درمانی شهید صدوقی یزد
This might be one of several explanations as to why elevated bacteria and the combination of specific pathogens in periodontal pockets can be linked to a history of ACS, said Stefan Renvert, DDS, PhD and Department of Health Sciences, Kristianstad University. We also found that the amount of periodontal bacteria results in an inflammatory response that elevates the white blood cell counts and high sensitivity C-reactive protein levels, which has also been linked in past studies to heart disease.. It was also found that the extent of alveolar bone loss was significantly greater among subjects with ACS. Seventy-seven percent of the participants in the ACS group and 42 percent in the control group demonstrated evidence of periodontitis. The extent of bone loss was more severe in the ACS group than in the non-ACS group.. Another reason people diagnosed with ACS may have higher oral bacteria could be due to their infectious susceptibility and lack of an adequate host inflammatory response, which ...
Teens involvement in numerous sports and recreational activities will damage maxillofacial features. Cases like a broken tooth increase the feasibilities of root infections & provide an obnoxious smile. A lot of them also get obstacles in eating & speaking during overbite. The lifestyle choices of teens also influence the challenges of cavities, impacted wisdom teeth, crowding issues, and gum diseases. The hectic schedule of adults demands a restricted brushing routine, not sufficient to remove plaques. Decays develop as a result of this and eventually result in severe conditions like oral cancer or gum infections. They also experience excessive edentulism imposed by smoking & lack of oral hygiene. Such voids spaces left by missing teeth leads to excessive alveolar bone loss in addition to deterioration in facial aesthetics ...
Curcumin is a yellowish polyphenol extracted from the rizome of a herbaceous tropical plant. It has multiple biological activities described, including anti-inflammatory, antioxidant, antiangiogenic, immunomodulatory, cytotoxic, antimicrobial and pro- and antiapoptotic activities. Its therapeutic application is actively evaluated in preclinical models and clinical studies of various diseases. In vivo use of curcumin is limited by its pharmacodynamic propereties, such as poor solubility in aqueous vehicles, low absorption rate in the gastrointestinal tract and short half-life in the peripheral circulation. The aim of this study was to evaluate the dose-response effect of a synthetic compound that is structurally to natural curcumin (CMC2.24) in a model of experimental periodontal disease that mimics the host-microbial interaction and the resultant inflammation and bone resorption that are hallmarks of this conditions in humans. Periodontal disease was induced in mice by injection of 30 ug LPS of ...
OBJECTIVE: The purpose of this study was to evaluate whether local administration of TIL could influence the expression of the inflammatory mediators IL-1β, TNF-α, MMP-8 and COX-2 in rats with experimental periodontitis (EP). METHODS: Twenty-four adult male rats (Rattus norvegicus, albinus, Wistar) were assigned to groups C, EP, EP-TIL (CControl group, EP-Periodontitis groups). On EP groups, a ligature was placed around maxillary 2nd molars on day 1. On group EP-TIL, 20 μL of TIL solution (1 mg/kg body weight) was injected into the subperiosteal palatal area adjacent to the maxillary 2nd molar every other day until euthanasia (day 11 ...
Study Alveolar Bone flashcards from Faith Villaceran's University of the East class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
(2005) Young et al. Tissue Engineering. Tooth loss accompanied by alveolar bone resorption presents a significant clinical problem. We have investigated the utility of a tissue-engineering approach to provide corrective therapies for too...
Particularly suited for treatment of smaller defects and periodontal bone defects. Can be cut to shape and size in dry or wet conditions. Does not stick to itself and to instruments. Can be easily repositioned, if needed. Exceptional adaptability to surface contour after rehydration.. ...
Vitamins and minerals essential for improving the nutritional environment of periodontal bone and tissue.These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
PROTOCOL OUTLINE: This is a randomized, double-blind, placebo controlled study. Patients are randomly assigned to receive placebo or conjugated estrogens and, if no prior hysterectomy, medroxyprogesterone. Patients also receive calcium supplementation therapy daily for 3 years.. Participants in the placebo group may be removed from study if bone loss exceeds 5% per year.. A study duration of 3 years is anticipated. ...
Purpose: The aim of this study was to compare vertical and horizontal mandibular alveolar bone resorption by measuring bone morphological variation in Kennedy Class II removable partial denture (RPD) wearers and non-wearers using cone-beam computed tomography (CBCT).. Materials and Methods: In total, 124 sites in the CBCT scans of 62 (29 RPD non-wearers, 33 RPD wearers) Kennedy Class II patients were analyzed retrospectively. Three-dimensional representations of the mandible with superimposed cross-sectional slices were developed with the CBCT scans to evaluate the mandibular alveolar height and width by measuring distances between the mandibular canal, mylohyoid ridge, alveolar crest, and lower border of the mandible in four regions (eight sites) of Kennedy Class II non-wearers and wearers of RPDs.. Results: Mandibular alveolar bone height and width were significantly lower in edentulous sites when compared with dentate sites in both Kennedy Class II non-wearers and wearers of RPDs (p , 0.05). ...
Oral bone loss is a major concern amongst a large population suffering from estrogen deficiency, osteoporosis and periodontal diseases. The clinical implication of oral bone loss is premature tooth loss. Mechanical loading has proven to be vital in maintaining the quantity and quality of the bone, particularly in impacted bone. Studies have shown that long bones (post-cranial) and alveolar bone (cranial) are both sensitive to mechanical environment through static and dynamic loading. It also has been suggested that whole body vibrations (WBV) at low-magnitude and high frequency are a non-invasive and non-pharmacological method to prevent bone loss, particularly in the long bones. However, not much has been said about the application of these low-magnitude high frequency loads on the alveolar bone. In this pilot study, it is determined if low magnitude of 0.3 g (where g = 9.8ms,super,-2,/super,) and high frequency of 50 Hz, localized vibrations can be transmitted to the alveolar bone and also ...
This study was planned to determine whether a short period dexamethasone treatment induce alveolar bone loss or not, therefore, twenty six male albino rabbits were divided into three groups as follow: Test groups I (10 rabbits) received 1.56 mg/kg dexamethasone intraperitoneal injection daily for two weeks, test group II (10 rabbits) received 3.12 mg/kg dexamethasone intraperitoneal injection daily, and the control group (6 rabbits) received saline solution for same period. The animals were sacrificed and histological sections were prepared from the alveolar bone of molar areas of mandible, as well as morphometric analysis of osteoclasts number was performed. The results showed a significant increase in the number of osteoclasts, which indicates that bone loss, is quite inevitable secondary to dexamethasone treatment even in a short period of treatment for two weeks.
In an article titled Periodontal Assessments of Postmenopausal Women Receiving Risedronate, a graduate of the Case Western Reserve University School of Dental Medicine, reports that drugs that are used to combat
Researchers at the University at Buffalo have been able to identify two key components in saliva that could be used to predict the amount of oral bone loss in future.
The treatment of intrabony defects is a real challenge in molar teeth as it is chronic, slowly progressing disease which needs timely intervention. Periodontal inflammation associated with intrabony defect is not a separate entity as it secondarily affects the pulp causing retrograde pulpitis. However, treatment of these lesions will be complicated due to extensive bone loss. The tooth was endodontically treated followed by periodontal surgery to eliminate the deep periodontal pocket and promote bone fill in osseous defect. PepGen P-15 composited with platelet rich plasma was utilized for enhancing bone formation. The combination of these graft materials provides synergistic effect on bone regeneration.
Researchers compared the effect of a daily atorvastatin 80 mg dose versus a 10 mg dose in a randomized, multi-center trial with 71 subjects with established atherosclerosis or risk factors for atherosclerosis. Patients were evaluated using F-Flurodexoyglucose positron emission tomography (FDG-PET) imaging. After 12 weeks, there was a significant reduction in periodontal inflammation in subjects randomized to the 80 mg dose (p=0.04). Reductions in periodontal inflammation were greatest in individuals with higher levels of periodontal inflammation at baseline (p=0.01) and in those with higher periodontal bone loss at baseline (p=0.03). The reductions in periodontal inflammation correlated with reductions in carotid inflammation (p,0.001). The impact of high-dose statin was greatest in individuals with evidence of active periodontitis and was evident after a four-week treatment period, said lead author Sharath Subramanian, MD, Massachusetts General Hospital and Harvard Medical School, Boston. We ...
Differing theories of the nature of periodontal disease progression have been proposed, but there is no convincing statistical evidence with which to choose between them. Three models for disease progression are developed, and their covariance structures are derived and shown to be hierarchical. The estimation of the covariance structures of...
Purpose: The purpose of this scholarly study is to evalute the anti-inflammatory ramifications of morus migra on experimentally-induced periodontitis in rats. Outcomes: Morus nigra treatment reduced tissues MMP-8 and MMP-13 amounts and there have been significant differences regarding tissue degrees of MMP-8 and MMP-13 between groupings PER and MN+PER (p=0.035, p=0.041). There have been no significant distinctions among all of the groupings serum degrees of MMP-8 and MMP-13 (p=0.067, p=0.082). In the histometric evaluation, alveolar bone loss was higher in the PER group compared to C and MN organizations (p=0.035). Immuno-histochemical staining of RANKL activities were found significantly lower (p=0.037) and OPG activities were found significantly higher in MN+PER group when compared to PER group (p=0.021). Summary: The present study shows that systemic administration of Morus nigra significantly inhibited the regional alveolar bone AC220 manufacturer resorption and contributes to periodontal ...
Results: No significant differences were found between both groups in survival, complications, or marginal bone resorption. One axially placed implant was lost at 58 months in group 1, rendering a cumulative survival estimate at 5 years of 96.7% and 98.3% in group 1 and the total sample, respectively (P = .317). Mechanical complications occurred in 16 patients (26.7%; n = 8 patients in each group; [P > .999]), consisting of fractures in the provisional prosthesis (n = 8 patients), chipped ceramics of the definitive prosthesis (n = 2 patients), loosening of prosthetic components (n = 5 patients), and fracture of an attachment screw (n = 1 patient). Biologic complications occurred in 5 patients (8.3%; group 1 = 4 patients; group 2 = 1 patient; [P = .161]), consisting of peri-implant pathology. The mean ± SD marginal bone loss was 2.02 ± 0.36 mm and 1.90 ± 0.69 mm for groups 1 and 2, respectively (P = .235). In group 1, the mean ± SD marginal bone loss was 1.92 ± 0.48 mm and 2.11 ± 0.44 mm ...
Parathyroid hormone is an endogenous hormone with potent anabolic and catabolic actions in bone. It has recently been approved for the treatment of osteoporosis and is marketed as FORTEO by Eli Lilly and Company. Numerous studies in humans have validated its use to increase bone mineral density and prevent fractures. Interest has also surfaced in its potential application in the treatment of non-osteoporotic fractures and several animal studies have supported this local application. Little is known regarding its use in treating conditions of the oral cavity, but animal studies suggest that bones of the oral cavity are responsive to the anabolic actions of PTH. Furthermore, a recent study indicated that in a canine model, PTH was effective at reversing periodontal bone loss. Studies from our laboratory indicate that patients with hyperparathyroidism (HPT) do not have an increase in periodontal disease as measured by attachment levels. In fact, in our patient population there was an increase in ...
The main finding is that the enhanced alveolar bone loss associated to age may be targeted by an appropriate dietary treatment. Our method uses biological knowledge expressed by Gene Ontology and generates a rule model associating this knowledge with minimal characteristic features of temporal gene expression profiles. The relatively low attack rate and also relative risk requires large sample sizes for free cialis generic testing hypotheses. From genes to function: the next challenge to understanding multiple sclerosis.. Recommendations for early diagnosis and intervention in autism spectrum disorders: an Italian-Israeli consensus conference. The purpose of this article is to reexamine some of the principles of correction. 6-Shogaol was shown to damage microtubules and discount generic cialis induce mitotic arrest. There was a weak association between adduct levels and daily cigarette consumption above 10 cigarettes per day. The results indicate that the PFD could be a useful tool for ...
The Straumann® Bone Level Tapered (BLT) Implant offers all the clinically proven features of the Straumann® Bone Level Implant line plus the advantages of a tapered implant body. This leads to excellent primary stability in soft bone and fresh extraction sockets. The tapered form adequately compresses the underprepared osteotomy. It also lets you effectively master your patients limited anatomy, such as facial undercuts, converging root tips, a concave jaw structure or narrow atrophied ridges ...
Australian Wine Cluster Supplementary Information Case Study Help, Case Study Solution & Analysis & Obesity induces gingival oxidative pressure, thats associated with the development of alveolar bone resorption. The antioxidant influence of hydrogen-load
Current therapeutics such as bisphosphonates or anabolic agents do not always effectively prevent or treat osteoporosis and inflammatory bone loss in rheumatoid...
I am new to the forum and tomorrow I am going in for the beginning of having dental implants due to bone loss! I have been so confused as to why I have had bone loss. I had PE with all 3 of my children and HELLP with my second. My youngest is 8 years old and I am approaching 49. My Mother had PE her first pregnancy and had dental bone loss issues. Back in the 1970s they told her here bone loss was due to her pregnancies. I am glad I decided to search for this. It gives me something to think about ...
31 years-old male patient was loss of anterior teeth for 1 year. . We have treated this case using Geistlich Bio-Oss® and Geistlich Bio-Gide® guide bone regeneration. After 6 months, the post-examination showed that that site had well-developed alveolar bone. After 1 year, permanent restoration was performed.. ...
Periodontal Fiber Definition Periodontal fiber is attached to the dentin of the root of the tooth by cementum and to the bone of the jaws by alveolar bone.
Bone loss is a problem that not only plagues the elderly, but the younger generation as well. This condition does not form overnight. Nobody can say that with just a ...
Implant dentistry in the esthetic zone is highly challenging. In recent years there are several studies, well defined approaches available on how to achieve pleasing outcomes. We must understand the biology of extraction sites and different treatment options for preserving or even reconstructing bony structures for predictable implant placement. This clinical and evidence based presentation will emphasize the importance of proper 3-dimensional implant placement, show different bone preservation techniques i.e P.E.T. (Partial Extraction Therapy) and how soft tissue grafting can effect the final end result. However we must admit that not only surgery but prosthetic skills have a major influence on our work. Implant placement must be determined with the prosthetic plan in mind! On the other hand abutment design, platform shifting concept as tissue molding tools and screw retained solutions will be high-lighted with lots of case presentations.. ...
TY - JOUR. T1 - Incisive canal cysts related to periodontal osseous defects. T2 - case reports.. AU - Mealey, B. L.. AU - Rasch, M. S.. AU - Braun, J. C.. AU - Fowler, C. B.. PY - 1993/6. Y1 - 1993/6. N2 - The incisive canal cyst is the most common non-odontogenic cyst of the oral cavity. While the cyst has frequently been described, the relationship between the lesion and adjacent periodontal osseous defects has rarely been reported. This paper describes the occurrence and treatment of incisive canal cysts in two patients with severe adult periodontitis on maxillary incisor teeth.. AB - The incisive canal cyst is the most common non-odontogenic cyst of the oral cavity. While the cyst has frequently been described, the relationship between the lesion and adjacent periodontal osseous defects has rarely been reported. This paper describes the occurrence and treatment of incisive canal cysts in two patients with severe adult periodontitis on maxillary incisor teeth.. UR - ...
Atherosclerotic vascular disease is a leading cause of myocardial infarction and cerebrovascular accident, and independent associations with periodontal disease (PD) are reported. PD is caused by polymicrobial infections and aggressive immune responses. Genomic DNA of Porphyromonas gingivalis, the best-studied bacterial pathogen associated with severe PD, is detected within atherosclerotic plaque. We examined causal relationships between chronic P. gingivalis oral infection, PD, and atherosclerosis in hyperlipidemic ApoEnull mice. ApoEnull mice (n = 24) were orally infected with P. gingivalis for 12 and 24 weeks. PD was assessed by standard clinical measurements while the aorta was examined for atherosclerotic lesions and inflammatory markers by array. Systemic inflammatory markers serum amyloid A, nitric oxide, and oxidized low-density lipoprotein were analyzed. P. gingivalis infection elicited specific antibodies and alveolar bone loss. Fluorescent in situ hybridization detected viable P. gingivalis
Clinicians very often have seen marginal bone loss around dental implants at the crest level early on after implant placement and uncovering. Early clinical publications had suggested that this bone loss occurred during the first year of loading. Thus, numerous attempts have been made to minimize or eliminate such bone loss. However, the timing and reason for this bone loss are not always apparent. The objective of this study was to review the evidence regarding marginal bone loss around dental implants from the standpoint of biologic consequences to help understand marginal bone changes around dental implants. One hypothesis for the bone loss around these implants was related to the presence of bacteria in the interfaces between the implant and abutment connections. The literature was reviewed regarding the three major types of implant-abutment crestal connections, including butt-joint, platform-switched, and no interface (tissue-level or one-body). This review article revealed that 1.5 to 2.0 ...
TY - JOUR. T1 - Supplementation of broccoli or Bifidobacterium longum-fermented broccoli suppresses serum lipid peroxidation and osteoclast differentiation on alveolar bone surface in rats fed a high-cholesterol diet. AU - Tomofuji, Takaaki. AU - Ekuni, Daisuke. AU - Azuma, Tetsuji. AU - Irie, Koichiro. AU - Endo, Yasumasa. AU - Yamamoto, Tatsuo. AU - Ishikado, Atsushi. AU - Sato, Takehiko. AU - Harada, Kayo. AU - Suido, Hirohisa. AU - Morita, Manabu. N1 - Funding Information: This study was supported by Grants-in-Aid for Scientific Research ( 20791642 ) from the Ministry of Education, Culture, Sports, Science, and Technology, Tokyo, Japan . The authors have no conflicts of interest to declare.. PY - 2012/4. Y1 - 2012/4. N2 - High-cholesterol diet enhances osteoclastic activity on alveolar bone by increasing serum lipid peroxidation. We hypothesized that supplementation with dietary antioxidants, such as found in broccoli and its fermented products, might suppress increases in serum lipid ...
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A range of regenerative treatments have been used for the treatment of periodontal infrabony defects. Guided tissue regeneration (GTR) and enamel matrix derivatives (EMD) are two popular treatment and they have both been used in combination with other treatment. This network meta-analysis was conducted to assess the potential effects of the various combinations. Unlike a [read the full story…]. ...
The suitability of a mouse model for host response in the induction of alveolar bone loss by Porphyromonas gingivalis was explored. The mouths of immunocompetent and severe combined immunodeficient (SCID) mice were infected with P. gingivalis ATCC 53977. P. gingivalis was not isolated from the mouths of these mice before infection, but was present at least 42 days after infection. P. gingivalis-specific IgG was present in sera from the infected, immunocompetent mice at the end of these experiments (42 days). Specific IgG was not present in sham-infected or uninfected immunocompetent mice, nor in any immunodeficient mice. Specific IgM was not present in any sera at 42 days. Infected, immunocompetent mice of two strains showed significant bone loss in comparison to sham-infected or uninfected immunocompetent mice (p | 0.05). Infected SCID mice, which are genetically lacking both B and T lymphocytes, also showed significant bone loss compared with sham-infected or uninfected SCID mice (p | 0.05
PURPOSE: The purpose of this animal study was to confirm that laser Doppler flowmetry (LDF) is a reproducible method for the assessment of maxillary and mandibular alveolar bone vascularity and that there is less vascularity in irradiated mandibular and maxillary bone compared to nonirradiated bone. MATERIALS AND METHODS: All maxillary and mandibular premolars and molars of 6 Gottingen minipigs were extracted. After a 3-month healing period, 3 minipigs received irradiation at a total dose of 24 Gy. Three months after irradiation, 5 holes were drilled in the residual alveolar ridge of each edentulous site in each minipig. Local microvascular blood flow around all 120 holes was recorded by LDF prior to implant placement. In 1 irradiated and 1 nonirradiated minipig, an additional hole was drilled in a right maxillary site to enable repeated LDF recordings. RESULTS: The alveolar bone appeared less vascularized in irradiated than in nonirradiated minipigs. The effect of radiation appeared more ...
Incisor trauma is common in children, and can cause severe complications during adolescent growth and development. This report describes the treatment of a 16-year-old patient with severe anterior open bite due to ankylosis of the maxillary left incisor after dental trauma as an 8-year-old. No examination or active treatment was undertaken until he was 16 years old. Clinical examination revealed that the maxillary left incisor was severely intruded accompanied by a vertical alveolar bone defect. Orthodontic treatment combined with surgical luxation took 3 years and 7 months. During treatment, the intruded incisor was moved to the occlusal level and the alveolar bone defect was restored, achieving normal occlusion. After two years of retention, the maxillary left incisor was retained in a stable normal position with a slightly reduced overbite. This case demonstrates that surgical luxation with orthodontic traction can be an effective approach, especially when the ankylosed tooth has a single root. Long
Dietary fish oil has been shown to inhibit bone resorption and, therefore, the aim of the present study was to test the hypothesis that fish oil alters lipopolysaccharide (LPS)-induced hydroxyapatite loss in rat alveolar bone. Rats were divided into four groups. The animals injected with saline or Escherichia coli-derived LPS into the maxillary alveolar mucosa on the buccoapical site of the molar region daily for 8 days were served as a negative or positive control, respectively. Other groups of animals were injected with LPS and orally treated with fish oil at the same day with or after LPS injection. The results of the present study showed that the hydroxyapatite contents of alveolar bone in rats treated with fish oil at the same day with or before LPS injection were significantly higher than those in rats injected with LPS alone, but still lower than those in untreated animals. Therefore, the present study suggests that oral treatment with fish oil may reduce LPS-induced hydroxyapatite loss ...
Academic Dissertations;Academic Dissertations--South Carolina;Periodontal Ligament;Osteonectin;Cysteine;Collagen;Dental Cementum;Collagen Type I;Tooth Loss;Alveolar Bone Loss;Transglutaminases;Periodontium;Extracellular Matrix; ...
Non-healing bone fractures and periodontal bone loss constitute significant clinical problems with few approved medical options. Bone repair is enhanced by the presence of osteoblasts or osteoblastic precursor cells. Subcutaneous adipose tissue is a plentiful, accessible, and replenishable source of human stromal cells for transplantation. In Phase I of this SBIR, we tested the hypothesis that human adipose tissue-derived stromal cells are capable of osteoblast function. Substantial in vitro data indicates that these stromal cells differentiate into cells biochemically and morphologically similar to osteoblasts. The ability of these cells to form bone in vivo was examined as well. Phase II of this SBIR will extend these in vivo experiments. Specific Aim 1 examines the ability of human adipose tissue-derived stromal cells to form ectopic bone in hydroxyapatite ceramic cubes implanted subcutaneously in immunodeficient mice. Specific Aim 2 explores whether the introduction of a modified bone ...
If you have been in practice long enough, you will have run into something like this eventually. This is a 76 year old farmer who has fairly obviously been grinding his teeth. In fact, you would be making a correct assumption. Note that the tooth wear is much worse anteriorly than it is in the posterior. As we will eventually see, this is diagnostic of abrasion from bruxism. But notice a few other less obvious things. You see no occlusal amalgam fillings in the posterior teeth. You see no plaque or redness around the gingiva. You see no active decay anywhere. Furthermore, the patient has no periodontal bone loss in spite of a serious bruxing habit. On the other hand, you do see a few buccal composite fillings along with severe buccal-cervical wear. We can conclude the following from these observations:. This patient has probably never used too much sugar. We conclude this by the lack of amalgam fillings in the intact molars and the occlusal of #4, the one surviving premolar.. The patient has ...
Our understanding about periodontal disease progression improved tremendously during 1960s, when animal and human experiments demonstrated the role of bacteria in the initiation of gingivitis and periodontitis 1, 2. These studies led to the proposal of the model of bacterial etiology of periodontal disease. Further investigations in this field led to the advancement of our knowledge of pathogenic bacteria causing disease progression. Specific Gram-negative, anaerobic, or microaerophilic bacteria were implicated in the causation of periodontitis 3-7. During late 1970s and early 1980s protective and destructive roles of the immunoinflammatory responses were described in health and disease 8-14.. Most of the models of periodontal disease progression in the late 1980s stated that specific bacteria initiated the disease process by activating host responses, which were protective and destructive. The actual destruction of connective tissue and bone resulted primarily from inflammatory chemical ...
A polylactide-polyglicolide(PLA-PGL) has been documented clinically to enhance bone regeneration in closed bone defects and to sustain periodontal healing in intrabony defects. So far, there are no controlled clinical studies to compare the effect of the PLA-PGL with the effect of other biological agents in treating deep intrabony defects. Aim of the study: to compare treatment of deep intrabony defects with PLA-PGL(Fisiograft®,Ghimas,Italy) to an enamel-matrix-protein-derivative(EMD; Emdogain®,Straumann AG,Waldenburg,Switzerland). Nineteen patients, displaying 26 intrabony defects, were randomly treated with PLA-PGL (test) or with EMD(control). Soft tissue measurements were made at baseline and 6 months after. No differences in the investigated parameters were observed at baseline between groups. Wilcoxon and Mann-Whitney tests were used for statistics. Alpha-error was set 0.05, the power-of-the-study 0.57. No adverse healing response was observed. Six months after, sites treated with ...
Non-contained intrabony defect treated using cerabone®, collprotect® membrane and Straumann® Emdogain® - Dr. T. Schwaar (2 ...
Evaluation of the Effect of Buccolingual and Apicocoronal Positions of Dental Implants on Stress and Strain in Alveolar Bone by Finite Element Analysis
BOSTON, USA: Studies have indicated that individuals with a high body mass index are more prone to developing periodontal disease than other people are. Being overweight or obese might also negatively affect ones response to nonsurgical periodontal therapy. In line with these findings, a recently published study has suggested that overweight or obese patients, particularly men, carrying a certain genetic variant were at an even greater overall risk of developing periodontitis.
MyJournals.org - Science - Displacement in root apex and changes in incisor inclination affect alveolar bone remodeling in adult bimaxillary protrusion patients: a retrospective study (Head & Face Medicine)
Calcium aids in development of strong bones and teeth. It also helps your heart, nerves, and muscles. Calcium deficiency often doesnt show symptoms right away, but leads to serious health problems over time. If calcium consumption isnt enough, your body may use the calcium from your bones instead, leading to bone loss.. Experts also believe that calcium deficiencies may be related to low bone mass and weakening of bones due to osteoporosis.. Calcium deficiency leads to convulsions and abnormal heart rhythm which can be life-threatening. Postmenopausal women experience greater bone loss due to changing hormones experiencing troubles absorbing calcium.The best sources of calcium are dairy products such as milk, yogurt, cheese, calcium-set tofu, and small fish with bones. Vegetables such as kale and broccoli also have calcium, and many cereals and grains are calcium-fortified.. ...
Overall marginal bone loss was not significantly different between the two treatment groups (EHC vs. IHC) at any time point. The mean difference of bone levels between EHC and IHC was 0.25 mm (95% CI: −0.18 to 0.69) at implant placement. Mean difference between IHC and EHC was −0.01 mm (95% CI: −0.34 to 0.36) at 3 months, 0.13 mm (95% CI: −0.48 to 0.22) at 6 months and 0.11 mm (95% CI: −0.45 to 0.25) at 12 months. All the implants showed good periodontal health at the 1-year-in-function visit, with no statistically significant differences between groups. At 12 months mean (± standard deviation) PI was 2 (± 1.5) for the EHC and 1.85 (± 1.58) for the IHC group (P = 0.57) with a mean difference between the two groups of 0.15 (95% CI: −0.56 to 0.85). Mean PD was 2.23 mm (± 0.52) for the EHC and 2.10 mm (± 0.39) for the IHC group (P = 0.39), with a mean difference between the two groups of 0.12 mm (95% CI: −0.08 to 0.33). At 12 months 41.4% of EHC and 43.6% of IHC implants ...
Objective The aim of the present study was to assess interventions and their consequences with regard to further bone loss at sites diagnosed with peri-implantitis. Materials and Methods In 2017, records of 70 patients diagnosed with moderate/severe peri-implantitis at >= 1 implant sites 4 years earlier were obtained. Changes of marginal bone levels during the study period assessed on radiographs and predictors of disease progression were identified by Cox regression and mixed linear modelling. Patient files were analysed for professional interventions related to the treatment of peri-implantitis. Results Mean bone loss (+/- SD) at implants diagnosed with moderate/severe peri-implantitis was 1.1 +/- 2.0 mm over the observation period of 3.3 years. While non-surgical measures including submucosal and/or supra-mucosal cleaning of implants were provided to almost all patients, surgical treatment of peri-implantitis was limited to a subgroup (17 subjects). Surgically treated implant sites ...
The molecular mechanisms controlling the differentiation of bone marrow stromal stem cells into osteoblasts remain mainly unknown. Similar results were found for the knockdown of the receptor- knockdown cells than control cells. Our data provide the first evidence that is involved in the osteogenic differentiation of bone tissue marrow stromal cells the legislation of the signaling pathway. Launch Osteoblasts differentiate from bone tissue marrow stromal cells (BMSCs), also called mesenchymal stem cells, that have the capacity to be adipocytes or fibroblasts [1]. Lately, individual alveolar-derived BMSCs (hAD-BMSCs) have already been effectively isolated and cultured [2]. These cells could be ideal for periodontal bone tissue regenerative medication because marrow bloodstream can be quickly aspirated from alveolar bone tissue during tooth removal and oral implant medical procedures [3, 4]. The bone tissue morphogenetic proteins (BMP) 2 signaling pathway can be an important regulator of ...
Ferreira CEA, Novaes AB Jr, Haraszthy VI, Bittencourt M, Martinelli CB, Luczyszyn SM. A clinical study of 406 sinus augmentations with 100% anorganic bovine bone. J Periodontol 2009;80(12):1920-1927.. Sinus grafting with anorganic bovine bone was performed in 222 patients requiring unilateral sinus grafting and 92 patients requiring bilateral sinus grafting; a total of 1,025 implants were placed (118 simultaneous with grafting and 907 at second stage surgery after 6-12 months). After 3 years, the implant survival rate was 98.1% (19 implants were lost), with no significant differences in survival between implants with rough or machined surfaces, or between implants placed in various heights of native bone. Histomorphometry showed 39.0 ± 12% new bone formation and 52.9% ± 9.3% marrow space.. Song D-W, Lee D-W, Kim C-K, Park K-H, Moon I-S. Comparative analysis of peri-implant marginal bone loss based on microthread location: a 1-year prospective study after loading. J Periodontol ...
Results: One patient (11-mm group) died before the 12-month evaluation and one patient (6-mm group) moved away. In addition, one patient in the 6-mm group lost one implant and no implants were lost in the 11-mm group. Two patients lost three restorations in the 6-mm group and no restorations were lost in the 11-mm group. From loading until the 60-month assessment, the mean marginal bone loss in the 6-mm group and the 11-mm group was 0.12 ± 0.36 mm and 0.14 ± 0.63 mm, respectively, without a significant difference (mean difference 0.02 mm; 95% CI -0.32 to 0.37; P = 0.884). Implant loss, restoration loss, screw loosening and porcelain chipping were defined as complications. Four patients in the 6-mm group and one patient in the 11-mm group had one or more complications, without a significant difference between the groups (95% CI 0.019 to 0.244; P = 0.198). The patient satisfaction was high in both groups (mean overall satisfaction in the 6-mm and the 11-mm groups was 9.4 ± 0.8 and 9.2 ± 0.8, ...
Results: One patient (11-mm group) died before the 12-month evaluation and one patient (6-mm group) moved away. In addition, one patient in the 6-mm group lost one implant and no implants were lost in the 11-mm group. Two patients lost three restorations in the 6-mm group and no restorations were lost in the 11-mm group. From loading until the 60-month assessment, the mean marginal bone loss in the 6-mm group and the 11-mm group was 0.12 ± 0.36 mm and 0.14 ± 0.63 mm, respectively, without a significant difference (mean difference 0.02 mm; 95% CI -0.32 to 0.37; P = 0.884). Implant loss, restoration loss, screw loosening and porcelain chipping were defined as complications. Four patients in the 6-mm group and one patient in the 11-mm group had one or more complications, without a significant difference between the groups (95% CI 0.019 to 0.244; P = 0.198). The patient satisfaction was high in both groups (mean overall satisfaction in the 6-mm and the 11-mm groups was 9.4 ± 0.8 and 9.2 ± 0.8, ...
Cimetidine is a powerful H2 receptor antagonist originally designed to treat ulcers by blocking the acid producing cells in the stomach. In the study three groups of rabbits were simultaneously induced with experimental periodontitis using P. gingivalis and treated with varying levels of topically applied cimetidine three times a week over a six-week period. Results showed that topical application of cimetidine at all concentrations inhibited inflammation and bone loss by approximately 90 ...
The PDL substance has been estimated to be 70% water, which is thought to have a significant effect on the tooths ability to withstand stress loads. The completeness and vitality of the PDL are essential for the functioning of the tooth. The PDL ranges in width from 0.15 to 0.38mm with its thinnest part located in the middle third of the root.[5] The width progressively decreases with age. The PDL is a part of the periodontium that provides for the attachment of the teeth to the surrounding alveolar bone by way of the cementum. The PDL appears as the periodontal space of 0.4 to 1.5 mm on radiographs, a radiolucent area between the radiopaque lamina dura of the alveolar bone proper and the radiopaque cementum. ...
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Historyczne dane o dokładnej lokalizacji autobusów z odbiorników GPS zamontowanych w autobusach próbkowane mniej więcej co 30 sekund. Zbiór danych jest aktualizowany codziennie ...
This results in a net loss of alveolar bone. Alveolar bone loss is closely associated with periodontal disease. Periodontal ... The alveolar process is also called the alveolar bone or alveolar ridge. The curved portion is referred to as the alveolar arch ... The supporting alveolar bone consists of both cortical (compact) bone and trabecular bone. The cortical bone consists of plates ... The loss of alveolar bone, coupled with attrition of the teeth, causes a loss of height of the lower third of the vertical ...
Zadik Y, Bechor R, Shochat Z, Galor S (April 2008). "[Ethnic origin and alveolar bone loss in Israeli adults]". Refu'at Ha-Peh ... Research has shown that smokers have more bone loss, attachment loss and tooth loss compared to non-smokers. This is likely due ... no evidence of bone loss over last five years Grade B: Moderate progression; < 2mm of bone loss over last five years Grade C: ... Amount and percentage bone loss radiographically Clinical attachment loss, probing depth Presence of furcation Vertical bony ...
... is a histologic term for the portion of the bone of the alveolar process that surrounds teeth and into which the ... Bundle bone is functionally dependent in that it resorbs following tooth extraction or loss. Araujo M, Lindhe J (2003). "The ... It can also be referred to as alveolar bone proper. ... Bones of the head and neck, All stub articles, Dentistry stubs) ... Edentulous Alveolar Ridge.". In Lindhe J, Karring T, Lang NP (eds.). Clinical Periodontology and Implant Dentistry (5th ed.). ...
"Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice". Journal of Bone and Mineral Research. 32 (5 ... "A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone ...
ISBN 81-89093-10-X. Levin, Liran (June 2007). "Alveolar Bone Loss and Gingival Recession Due to Lip and Tongue Piercing". N Y ... In some cases, the alveolar tooth-bearing bone is also involved, jeopardizing the stability and durability of the teeth in ... Bone, Angie; Fortune Ncube; Tom Nichols; Norman D Noah (21 June 2008). "Body Piercing in England: a Survey of Piercing at Sites ... It was popular among the Aztecs, the Mayans and the tribes of New Guinea, who adorned their pierced noses with bones and ...
Evidence of alveolar bone loss is also required to differentiate between true bone loss and not attributions of gingival oedema ... The cumulative effects of alveolar bone loss, attachment loss and pocket formation is more apparent with an increase in age. ... Usually, a horizontal pattern of bone loss would be found however, vertical (infrabony) bone loss may also be present on ... However, usually when presenting complaints do arise the effects of mobility and alveolar bone loss have become severe. A full ...
Extension of the lesion into alveolar bone, periodontal ligament with significant bone loss Continued loss of collagen ... The disease consists of a chronic inflammation associated with loss of alveolar bone. Advanced disease features include pus and ... drifting and eventual loss Because bone loss makes its first appearance in the advanced lesion, it is equated with ... Features of the Established Lesion: Predominance of plasma cells without bone loss Presence of extravascular immunoglobulins in ...
... all of them exhibited mild to moderate alveolar bone loss resulting from periodontal disease (the wearing away of the bone ... three exhibited no pathologies of the alveolar bone. Measuring the distance between the alveolar bone and the cementoenamel ... Ripamonti, U. (1989). "The Hard Evidence of Alveolar Bone Loss in Early Hominids of Southern Africa". Journal of Periodontology ... the lower part of the upper arm bone), a proximal right ulna (upper part of a lower arm bone) and a distal phalanx bone of the ...
... seven exhibited mild to moderate alveolar bone loss resulting from periodontal disease (the wearing away of the bone which ... Ripamonti, U. (1989). "The Hard Evidence of Alveolar Bone Loss in Early Hominids of Southern Africa". Journal of Periodontology ... The trabecular bone at the hip joint is distinctly humanlike, which would be inconsistent with the great degrees of hip loading ... The leg bones clearly show that A. africanus habitually engaged in bipedal locomotion, though some aspects of the tibiae are ...
Untreated, these diseases can lead to alveolar bone loss and tooth loss. As of 2013[update], periodontal disease accounted for ... ongoing chronic stress are more likely to have clinical attachment loss and decreased levels of alveolar bone due to ... In periodontal health, the alveolar bone surrounds the teeth and forms the bony socket that supports each tooth. The buccal and ... encompasses a number of diseases of the periodontal tissues that result in attachment loss and destruction of alveolar bone. ...
This condition increase alveolar bone loss, attachment loss, tooth mobility, and finally tooth loss. It can cause other ... involvement in bone infections: a review". International Journal of Antimicrobial Agents. 41 (6): 509-15. doi:10.1016/j. ...
Stage 2 (PD2) - early periodontal disease with less than 25% attachment loss of the tooth from the alveolar bone. The treatment ... The hallmark feature of periodontitis is attachment loss of the tooth from the alveolar bone. Periodontitis is an irreversible ... Stage 4 (PD4) - advanced periodontal disease with more than 50% attachment loss of the tooth from the alveolar bone. Extraction ... Stage 3 (PD3) - established periodontal disease with 25-50% attachment loss of the tooth from the alveolar bone. Treatment ...
They describe the development of lateral plates on the alveolar margins of tooth-bearing bones. These plates can be used to ... strip foliage, the eusauropod's "U-shaped" jaws create a wide bite, and their loss of "fleshy cheeks" increased the gape. The ... Unlike prosauropods and theropods, which have a snout with smooth, unprotruding alveolar and subnarial regions, eusauropods ...
They are also attached to the gingival (gum) tissue that covers the alveolar bone by an attachment apparatus; because this ... Teeth are attached to the surrounding and supporting alveolar bone by periodontal ligament (PDL) fibers; these fibers run from ... of the alveolar bone, it is termed the supracrestal attachment apparatus. The supracrestal attachment apparatus is composed of ... Connective tissue attachment loss refers to the pathological detachment of collagen fibers from cemental surface with the ...
This may further lead to furcal involvement through loss of clinical attachment and alveolar bone. A cursory clinical ... This is because neutrophils, which are rich sources of PGE2, are present when the majority of rapid bone loss occurs during the ... injured site and cause resorption of the periapical alveolar bone. It is possible that after conventional endodontic therapy ... Regeneration of the bone has been demonstrated to occur, on average, at a rate of 3.2 mm² per month, and studies suggest that ...
... the alveolar ridge has a mean loss of width of 3.8mm, and a height loss of 1.24mm within six months. This loss of bone volume, ... loss in bone volume in the first six months. Bone loss, can compromise the ability to place a dental implant (to replace the ... Socket preservation or alveolar ridge preservation is a procedure to reduce bone loss after tooth extraction. After tooth ... Socket preservation attempts to prevent bone loss by bone grafting the socket immediately after extraction. With the procedure ...
Julihn A, Barr Agholme M, Modeer T (June 2008). "Risk factors and risk indicators in relation to incipient alveolar bone loss ... If this is not treated, the inflammation will lead to the bone loss and will eventually lead to the affected teeth becoming ... In the group that was instructed to rinse with saline, the prevalence of alveolar osteitis was less than in the group that did ... Severe gum disease causes at least one-third of adult tooth loss. Since before recorded history, a variety of oral hygiene ...
Effect of dietary vitamin E supplement and rotational stress on alveolar bone loss in rice rats (subscription required). ... Effect of stannous fluoride and iodine on root caries and bone loss in rats. Ohio Journal of Science 88(3):99-100. Benson, D.E ... Vitamin E, fluoride, and iodide protect against bone loss associated with this disease in the rice rat and a high-sucrose diet ... The nasal and premaxillary bones extend back beyond the point where the lacrimal, frontal, and maxillary bones meet. In P. o. ...
Interproximal and horizontal alveolar bone loss in mouse models are seen in coinfections involving P. gingivalis and Treponema ... Vaccines made from P. gingivalis CPS apparently impair oral bone loss in murine models. These vaccines have been able to elicit ... In contrast, germ free mice inoculated with a P. gingivalis monoinfection incur no bone loss, indicating that P. gingivalis ... In these models, P. gingivalis inoculation causes significant bone loss, which is a significant characteristic of the disease. ...
Some loss of connective tissue attachment and alveolar bone loss is normal during a two-year course of orthodontic treatment. ... Tooth loss implies in loss of several orofacial structures, such as bone tissues, nerves, receptors and muscles and ... Dental abscesses can cause resorption of bone and consequent loss of attachment. Depending on the type of abscess, this loss of ... Severe infection at the apex of a tooth can again result in bone loss and this in turn can cause mobility. Depending on the ...
Loss of teeth alters the form of the alveolar bone in 91% of cases. In addition to this resorption of bone in the vertical and ... The alveolar bone is unique in that it exists for the sake of the teeth that it retains; when the teeth are absent, the bone ... Bone loss with missing teeth, partials and complete dentures is progressive. According to Wolff's law, bone is stimulated, ... The alveolar ridges are columns of bone that surround and anchor the teeth and run the entire length, mesiodistally, of both ...
Stippling only presents on the attached gingiva bound to underlying alveolar bone, not the freely moveable alveolar mucosa or ... unless it is smooth due to a loss of previously existing stippling. Stippling is a consequence of the microscopic elevations ...
The alveolar bone typically overgrows, but root surfaces can be exposed to the oral environment increasing likelihood of dental ... The changes are most visible in the first year after the loss of the opposing tooth. A systematic review on the treatment need ... "Occlusal Changes Following Posterior Tooth Loss in Adults. Part 1: A Study of Clinical Parameters Associated with the Extent ...
If done successfully, it is able to ensure stable alveolar bone volume as there is continuous stimulation of the periodontal ... At present, it has been theorised that evolutionary change is working to decrease the human dentition by the loss of an incisor ... The primary molars present also functions as a space maintainer, prevent alveolar bone resorption and delays future ... However, bone grafting can be carried out to overcome this. Hypodontia is less common in the primary dentition, with reported ...
Alveolar crest fibers (I) run from the cervical part of the root to the alveolar bone crest Horizontal fibers (J) attach to the ... All of these can lead to loss of vitality of the PDL and depending on the duration of storage, this can affect the success of ... bone remodelling is initiated by the PDL in which forces are transmitted from the tooth to the alveolar bone. Fibroblasts of ... The PDL is a part of the periodontium that provides for the attachment of the teeth to the surrounding alveolar bone by way of ...
... gingival recession and loss of alveolar bone crest height. In these cases, crown lengthening surgery should be considered. ... Secondly, the biologic width, the mandatory distance (roughly 2 mm) to be left between the height of the alveolar bone and the ... potentially resulting in the loss of healthy, natural tooth structure for this purpose, the all-porcelain CAD/CAM crown can be ... sound tooth structure may need to be sacrificed in order to prevent further more substantial and uncontrolled loss of tooth ...
In cases where recession is not accompanied by periodontal bone loss, complete or near complete coverage of the recession area ... It may exist with or without concomitant decrease in crown-to-root ratio (recession of alveolar bone). Various classifications ... Gingival recession, also known as receding gums, is the exposure in the roots of the teeth caused by a loss of gum tissue and/ ... Depending on the shape of the gum recession and the levels of bone around the teeth, areas of gum recession can be regenerated ...
Patients often present with early-onset aggressive periodontitis associated with advanced alveolar bone loss and tooth mobility ... Bone marrow transplants appear to have been successful in several patients. Infections are treated with antibiotics and ... The diagnosis is confirmed by bone marrow smears that show "giant inclusion bodies" in the cells that develop into white blood ...
The shape of the alveolar bone in regions of bone loss varies depending on the buccal-lingual length (or cheek-to-tongue length ... In healthy situation, there should be no sign of bone loss other than potential bone remodelling at the alveolar crest ... There have been reports of bone loss without any accompanying sign of soft tissue inflammation. Without evidence of bone loss, ... of the bone. Where this length is greater than the extent of the peri-implantitis, the region of bone loss can take the shape ...
A suprabony pocket occurs when there is horizontal bone loss, the bottom of the pocket is coronal to the alveolar bone. An ... infrabony pocket occurs when there is vertical bone loss where the bottom of the pocket is apical to the alveolar bone. ... pockets can cause the loosening and loss of dentition due to destruction of supporting tissues including the alveolar bone, PDL ... There are two types of periodontal pockets that are determined by the type of bone loss present. ...
... as well as surrounding alveolar bone by osteoclasts) and become absorbed by the forming permanent teeth. The process of ... Various cultures have customs relating to the loss of deciduous teeth. In English-speaking countries, the tooth fairy is a ... Also the muscles of the jaw and the formation of the jaw bones depend on the primary teeth to maintain proper spacing for ... The primary teeth maintain the arch length within the jaw, the bone and the permanent teeth replacements develop from the same ...
2. The increased distance between inter-proximal contact position to bone crest, example to that is the naturally occurring ... 5. Periodontal disease and loss of attachment, resulting in recession. 6. Tooth morphology and abnormal crown and restoration ... Between Roots on the Existence of Interdental Papillae According to the Distance From the Contact Point to the Alveolar Crest ...
In practice, at a conventional alveolar pO2 of 135 mmHg, PFCs will not be able to provide sufficient oxygenation to peripheral ... loss of RBCs. Stored RBCs are then reinfused, usually 1 to 7 days before a high-endurance event. As a significant amount of ... is a glycoprotein hormone produced by the interstitial fibroblasts in the kidney that signal for erythropoiesis in bone marrow ...
When the attachments of the teeth to the bone are involved, the term NUP is used. Treatment of ANUG is by removal of dead gum ... Necrotizing ulcerative periodontitis (NUP) is where the infection leads to attachment loss, and involves only the gingiva, ... periodontal ligament and alveolar ligament. Progression of the disease into tissue beyond the mucogingival junction ... lips or the bones of the jaw. As stated, the condition can occur and be especially dangerous in people with weakened immune ...
This injury involves the alveolar bone and may extend beyond the alveolus. There are five different types of alveolar fractures ... Trauma is the most common cause of loss of permanent incisors in childhood. Dental trauma often lead to the main complication ... Dental trauma refers to trauma (injury) to the teeth and/or periodontium (gums, periodontal ligament, alveolar bone), and ... tooth should be gently rinsed under tap water and immediately re-planted in its original socket within the alveolar bone and ...
Becks, H.; Weber, M. (1931). "The Influence of Diet on the Bone System with Special Reference to the Alveolar Process and the ... Excessive plaque formation can lead to severe inflammation of the gums which may result in the loss of teeth. This plaque is ... Deficiencies negatively impact parts of the teeth including the gingivae, periodontal ligaments and the alveolar bone, leading ... it can result in resorption and reduction of the alveolar bone as shown in Henrikson's studies when dogs were fed a low calcium ...
Xing, L.; Bell, P.R.; Rothschild, B.M.; Ran, H.; Zhang, J.; Dong, Z.; Zhang, W.; Currie, P.J. (2013). "Tooth loss and alveolar ... The astragalus bone (ankle bone) was separated from the tibia and the calcaneum, and formed half of the socket for the fibula. ... These bones were coossified together (fusion during bone tissue formation), so the sutures between them cannot be determined. ... CT scans show that air sacs (pockets of air that provide strength for and lighten bones) were present in the bones that ...
This causes proteinuria by damaging the basement membrane and creating a loss of negative charge. These are anionic deposits ... If a patient has DPGN with underlying anti-GBM then they can experience alveolar hemorrhage and respiratory issues.[citation ... and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Kidney Int Suppl. 2017;7:1-59". Kidney ...
The damage to the endothelium and the alveolar epithelium results in the creation of an open interface between the lung and the ... Fluid filled airspaces, loss of surfactant, microvascular thrombosis and disorganized repair (which leads to fibrosis) reduces ... This agent also causes respiratory tract lesions, bone marrow depression, and eye damage, the epithelial tissues of these ... Uchida T, Makita K. (2008) Acute lung injury and alveolar epithelial function. Masui. 57:51-9. Tang PS, Mura M, Seth R, Liu M ...
The soft tissues are protected and resorption of the alveolar bone at the saddle areas is likely to be slow. However, with ' ... fix/replace the prosthesis if damaged Modifications can be made to the prosthesis in some cases following additional tooth loss ... Force placed on these areas dissipates into the alveolar bone and will cause resorption over time. Dentures quickly begin to ... feel ill fitting as the shape of the alveolar ridge changes. When choosing the teeth to support the denture, They must have the ...
Parafunction Following the loss of teeth, there occurs a resorption (or loss) of alveolar bone, which continues throughout life ... Increased retention of prosthesis Reduced alveolar bone resorption and preservation of alveolar ridge Reduced horizontal forces ... recession of alveolar bone causing loss of fit of prosthesis, broken dentures, etc.). Whether or not they are deemed ... with some basilar loss evident Alveolar bone resorption is an important consideration when designing complete dentures. In the ...
... overexpressing rabbits exhibited reduced tissue destruction and bone loss in a model of periodontitis. Finally, Control ... it is less strongly expressed in alveolar macrophages, tissue mast cells, tissue fibroblasts, circulating blood neutrophils, ... Kelavkar and Badr (1999) described experiments yielding data that supported the hypothesis that loss of the TP53 gene, or gain- ...
... and alveolar bone in the oldest herbivorous tetrapods, and their evolutionary significance". PLOS ONE. 8 (9): e74697. Bibcode: ... ISBN 978-1-85391-092-0. Robertshaw, David (2006). "Mechanisms for the control of respiratory evaporative heat loss in panting ... In many amphibians there are also vomerine teeth attached to the bone in the roof of the mouth. The mouths of reptiles are ... The upper teeth are embedded in the upper jaw and the lower teeth in the lower jaw, which articulates with the temporal bones ...
It is thought to be created by an ectopic portion of salivary gland tissue which causes the bone of the mandible to remodel ... Hyposalivation often results in a dry mouth condition called xerostomia, and this can cause tooth decay due to the loss of the ... It appears below the inferior alveolar nerve canal in the posterior region of the mandible. Salivary gland dysfunction affects ...
... alveolar bone loss MeSH C07.465.714.204 - furcation defects MeSH C07.465.714.258 - gingival diseases MeSH C07.465.714.258.250 ... tooth loss MeSH C07.465.714.836 - tooth migration MeSH C07.465.714.836.535 - mesial movement of teeth MeSH C07.465.714.898 - ... periodontal attachment loss MeSH C07.465.714.470 - periodontal cyst MeSH C07.465.714.533 - periodontitis MeSH C07.465.714.533. ...
Artificial grafts such as demineralized bone, recombinent bone morphogenic protein or a mix of harvested bone and artificial ... Late secondary grafting (after eruption of the canine) has also been advocated but has been largely abandoned due to the loss ... where the bone defect is filled with bone or bone substitute, and any holes between the mouth and the nose are closed. An ... Lilja, Jan (2009). "Alveolar bone grafting". Indian Journal of Plastic Surgery. 42 (3): S110-5. doi:10.4103/0970-0358.57200. ...
... alveolar abscess amebic abscess apical abscess appendiceal abscess Bartholin abscess Bezold abscess bicameral abscess bone ... and loss of function. There may also be high temperature (fever) and chills. If superficial, abscesses may be fluctuant when ... periodontal abscess apical periodontal abscess lateral periodontal abscess root abscess gingival abscess lateral alveolar ...
Often, a new nasal bone will have to be interpositioned, using a bone transplant. Complications of this procedure are: bleeding ... Different mutations can occur in the ALX3 gene, but they all lead to the same effect: severe or complete loss of protein ... The severe group presents with a complete cleft of the upper lip and alveolar ridge. Nervous system lipomas are rare congenital ... In those cases, bone tissue from the skull or the ribs is used. However, this may give rise to serious complications such as ...
Labials: /pʼ/ > /pʃʼ/ / /t͡ʃʼ/ /pʰ/ > /pʃʰ/ / /t͡ʃʰ/ /b/ > /bʒ/ / /ʒ/ /f/ > /fʃ/ / /ʃ/ Alveolars: /tʼ/ > /t͡ʃʼ/ /tʰ/ > /t͡ʃʰ/ / ... ke bone‡ ('I saw') [kʼɪbonɪ] ho kena‡ ('to enter') [hʊkʼɛnɑ] > ho kenya‡ ('to insert') [hʊkʼeɲɑ] These changes are usually ... loss of labialization + gaining of ejective quality) *m̩pʃʼa (as found in Northern Sotho) > (heterorganic simplification + ... Originally, this was an alveolar rolled lingual, but today most individuals pronounce it at the back of the tongue, usually at ...
KRT6A Paget disease of bone; 602080; PDB4 Paget disease of bone; 602080; SQSTM1 Paget disease of bone; 602080; TNFRSF11A Paget ... alveolar; 268220; PAX3 Rhabdomyosarcoma 2, alveolar; 268220; PAX7 Rhabdomyosarcoma; 268210; SLC22A1L Rhabdomyosarcoma, alveolar ... ABCA1 Hearing loss, low-frequency sensorineural; 600965; WFS1 Heart block, nonprogressive; 113900; SCN5A Heart block, ... ATP1A2 Alveolar capillary dysplasia with misalignment of pulmonary veins; 265380; FOXF1 Alveolar soft part sarcoma; 606243; ...
Platelet-rich fibrin (PRF) is a postoperative method used to heal the alveolar socket following the removal of the mandibular ... This includes dental factors such as tooth crown size and primary tooth loss. Skeletal factors which include growth of the ... bone restoration and soft tissue healing. Further studies with larger study samples are needed to validate current theories. ... Temporary and permanent inferior alveolar nerve (IAN) damage is a known complication of the surgical removal of impacted lower ...
Bone metabolism can be regulated by central sympathetic outflow, since sympathetic pathways innervate bone tissue. A number of ... The leptin from the mesenchyme, in turn, acts back on the epithelium at the leptin receptor carried in the alveolar type II ... When both leptin and amylin were given to obese, leptin-resistant rats, sustained weight loss was seen. Due to its apparent ... Leptin can affect bone metabolism via direct signalling from the brain. Leptin decreases cancellous bone, but increases ...
Guided bone reconstruction is a technique in which bone growth is enhanced by preventing soft tissue ingrowth into the desired ... Alveolar mucosa is non keratinized oral epithelium and is located apical to the keratinized tissue, delineated by the ... Exposure of the tooth root due to loss of keratinized tissue around the neck of a tooth is referred to as gingival recession. ... Should gum recession continue, bone and keratinized tissue will be at greater risk of being damaged and permanently lost around ...
... together with some intrusion of the anterior teeth and potential growth of the alveolar bone. This will allow the posterior ... The Dahl appliance can increase the height of a patient's face and correct for this loss of facial height. The original Dahl ... No mucosal-bone component should be involved Thickness of the material placed should directly correspond to the required amount ... Tooth preparation and the associated loss of coronal tissue can risk further insult to the pulp and limit the options for ...
... forces by resorbing some of the bone of the alveolar crest, which may result in increased tooth mobility, however these changes ... and does not necessarily indicate that the loss of tooth substance is ongoing. People who clench and perform minimal grinding ... The Geats (the warriors who hunt the troll) alternatively translate the name as "grinder of men's bones" to demonize their prey ...
... the loss of periodontal fiber, the clinical attachment loss (CAL), alveolar bone loss, and help in assessing and determining a ...
... and loss of sensation due to the location of the inferior alveolar nerve. Anti-inflammatory medication can be used to slow the ... is a temporomandibular joint disorder in which one or both of the mandibular condyles are broken down in a bone resorption ... These include: Occlusion Anterior open bite Receding chin Loss of ramus height Antegonial notching Hyperplasia of the coronoid ...
Non-contact activities keep joints and bones healthy and maintain fitness over time. Exercise also helps promote weight loss, ... Agbaje JO, Salem AS, Lambrichts I, Jacobs R, Politis C (2015). "Systematic review of the incidence of inferior alveolar nerve ... As opposed to putting an implant on top of the chin bone to bring it forward, an alternative approach is to cut the chin bone ... The bones are cut, reshaped or partially removed to realign the load-bearing surfaces of the joint. Adjustments are made to ...
... alveolar bone loss MeSH C05.116.264.579 - osteolysis MeSH C05.116.264.579.052 - acro-osteolysis MeSH C05.116.264.579.052.400 - ... MeSH C05.116.070.265 - bone cysts, aneurysmal MeSH C05.116.099.052 - acro-osteolysis MeSH C05.116.099.052.400 - Hajdu-Cheney ... fibrous dysplasia of bone MeSH C05.116.099.708.375.199 - cherubism MeSH C05.116.099.708.375.372 - fibrous dysplasia, monostotic ... bone demineralization, pathologic MeSH C05.116.198.247.400 - decalcification, pathologic MeSH C05.116.198.371 - mucolipidoses ...
Topical injection of osteoprotegerin prevents alveolar bone loss in rat experimental periodontitis DOI 50 References ... systemic administration of OPG has been reported to be effective for decreasing alveolar bone loss in rat models of ... These results demonstrate that topical injection of OPG could prevent alveolar bone loss in rat experimental periodontitis, ... Micro-CT analysis revealed that the distance from the cement-enamel junction to the alveolar bone crest (CEJ-ABC) was higher in ...
Stay connected to all updated on Alveolar Bone Loss ... Tag: Alveolar Bone Loss. You Searched For "Alveolar Bone Loss" ... Convolutional neural networks trained algorithm may help diagnose alveolar bone loss in periapical X-rays Dr. Shravani Dali. 23 ...
Increased adipose tissue may induce alveolar bone loss, neutrophil recruitment, and changes in the oral biofilm, similar to ... Obesity may induce changes in the oral microbiota and neutrophil recruitment, which are associated with alveolar bone loss. ... Dysbiotic oral microbiota contributes to alveolar bone loss associated with obesity in mic ... Dysbiotic oral microbiota contributes to alveolar bone loss associated with obesity in mice. ...
PI3Kγ controls IL-17A expression and attenuates alveolar bone loss in an experimental periodontitis model *Marcelo Franchin ... Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kgamma-dependent fluid-phase ... Neutrophils lacking phosphoinositide 3-kinase γ show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis. ...
Augustine frequently treats Alveolar Bone Loss, Biocon Dental Implants, and Bleeding Gums. See all procedures and conditions Dr ...
Analysis has shown that there is significant difference in alveolar bone loss in experimental group and control group (p=0.002 ... Objective: This retrospective study aims to evaluate the possible effects of antihypertensive drugs on alveolar bone loss in ... Effects of Antihypertensive Drugs on Alveolar Bone Loss in Patients with Chronic Periodontitis: A Retrospective Study/ AL- ... Conclusion: Antihypertensive drugs appear to have a positive effect on alveolar bone loss progression. Patients under these ...
Vertical and horizontal alveolar bone loss follows tooth removal. Maintaining good alveolar ridges has an impact on future ... Review suggests that via socket filling with a bone graft can help preserve alveolar ridge. 11 Responses » ... Tagged with: allograft, alloplast, alveolar ridge preservation., bone grafting, oral and maxillofacial surgery, xenograft ... Shanbhag S, Shanbhag V. Clinical Applications of Cell-Based Approaches in Alveolar Bone Augmentation: A Systematic Review. Clin ...
Alveolar bone loss in obese subjects. Journal of the International Academy of Periodontology, 2005, 7(2):34-8. ... found that obesity was significantly associated with alveolar bone loss among adults, with a stronger association in females [ ... periodontal clinical attachment loss (CAL): this was assessed at 6 sites per tooth using the indirect measurement method ... Normal, overweight and obese females had a mean attachment loss of 0.2 mm, 1.5 mm and 2.1 mm respectively, with a statistically ...
Canadian Research Team to Study Markers of Alveolar Bone Loss. May 25, 2012 Topics: education / diagnosis / systemic disease / ...
... an inflammatory process limited to the mucosal epithelial tissue surrounding the cervical portion of the teeth and the alveolar ... As this persistent inflammation continues, periodontal ligaments break down and destruction of the local alveolar bone occurs. ... Loss of the gingival tissue is seen, making the teeth appear long. Even more effacement of the papillae is present. Heaped up ... Loss of the gingival tissue is seen, making the teeth appear long. Even more effacement of the papillae is present. Heaped up ...
Can nonstandardized bitewing radiographs be used to assess the presence of alveolar bone loss in epidemiologic studies? ... The association between tooth loss and coronary heart disease in men and women. Hung HC, Joshipura KJ, Colditz G, Manson JE, ... The association between tooth loss and the self-reported intake of selected CVD-related nutrients and foods among US women. ...
Keywords: periodontal tissues, sonodynamic therapy, histology, alveolar bone loss, animal studies ... The animals treated by SDT showed less bone loss (P0.05).Conclusion: Our results suggest that HMME-mediated SDT can effectively ... Keywords: periodontal tissues, sonodynamic therapy, histology, alveolar bone loss, animal studies. A corrigendum has been ... significant alveolar bone loss was observed after 7 days; progressive changes continued until the end of the experimental ...
... inflammatory condition that destroys periodontal ligament fibers and alveolar bone and can eventually cause tooth loss. ... Weight loss. * Blurred vision. * Thirst. * Excessive urination. * Enuresis. * Abdominal pain. * Nausea or vomiting. Results of ... Regular aerobic exercise has been shown to be a useful adjunct to weight loss and to have a beneficial effect on lipids, ... Deformed feet will not fit into ordinary shoes, although the patient, because of loss of sensation, may think they fit. The ...
K. Shoji, M. Ohtsuka-Isoya, H. Shimauchi, and H. Shinoda, "Effects of lactation on alveolar bone loss in experimental ... Radiographic films were taken and the lost alveolar bone level was evaluated (Figure 5(a)). The lost alveolar bone level was ... 100%. (b) The periodontal bone-supporting ratio was measured and shown. (. ; ; were compared with control group. ; ; were ... It can destroy the surrounding connective tissue and adjacent alveolar bone and eventually causes tooth loss [2, 3]. The immune ...
... infection and loss of alveolar bone," Lau says. The alveolar bone plays an essential role in keeping your teeth in place, so ... Crooked teeth can also affect your gums, jaw bone, and even your mental well-being. Here are four common consequences of ... In fact, periodontitis is known to cause tooth loss, receding gums, and a misaligned bite. ...
Alveolar bone loss on radiography was used to assess periodontitis.. The researchers report their findings in the May issue of ... "Seeing alveolar bone loss on X-rays indicates the infection has existed for decades, making it clear that periodontitis ... On multivariate analysis, each millimeter reduction in alveolar bone was associated with a 5.23-fold rise in the risk of tongue ...
Professor, Kinesiology (primary) Office: CRN422 905 688 5550 x5157 [email protected] the Nutrition, Bone and Oral Health ... The ovariectomized rat as a model for studying alveolar bone loss in postmenopausal women. BioMed Research International. 2015: ... EARLY DIET FOR PROGRAMMING BONE HEALTH *Wakefield CB, *Yumol JL, *Sacco SM, Sullivan PJ, Comelli EM, Ward WE. Bone structure is ... Bone Reports, 10:100191, 2019. *Yumol JL, *Wakefield CB, *Sacco SM, Sullivan PJ, Comelli EM, Ward WE. Bone development in ...
In EIP, treatment with A.muciniphila resulted in a decreased alveolar bone loss. In vitro, the addition of A.muciniphila to P. ... Bone-marrow macrophages (BMM?) and gingival epithelial cells (TIGK) were exposed to both bacterial strains and the expression ... Akkermansia muciniphila reduces Porphyromonas gingivalis-induced inflammation and periodontal bone destruction  Huck, Olivier ... Results In a model of calvarial infection, A.muciniphila decreased inflammatory cell infiltration and bone destruction. ...
Increased mobility of teeth may also be observed in association with clinical attachment loss and bone loss. ... NUP lesions extend into and destroy the alveolar bone. Patients with NUP frequently present with exposed bone, gingival ... clinical attachment loss, and bleeding on probing. Radiographic analysis can reveal the presence of periodontal bone loss with ... NUP is characterized by rapid destruction of bone that often leads to tooth loss, severe deep jaw pain, widespread soft tissue ...
The extent of alveolar bone loss is associated with impaired glucose tolerance in Japanese men. Saito, T., Murakami, M., ... Mizu-Uchi, H., Matsuda, S., Miura, H., Higaki, H., Okazaki, K. & Iwamoto, Y., Dec 2006, In: Journal of Bone and Joint Surgery ... The effect of hydrogen on fatigue crack growth behavior and ductility loss of austenitic stainless steels. Kanezaki, T., Mine, ...
Indications: 1. Important bone loss around one or several roots. 2. Class II or III furcation exposures. 3. Adjacent tooth ... Infrabony pocket. Periodontal pocket whose bottom is situated coronal to the crest of the surrounding alveolar bone. ... Suprabony pocket. Periodontal pocket whose bottom is situated apical to the crest of the surrounding alveolar bone. ... Attachment loss. It is the absolute measure of the loss of periodontal support. It is measured from the junctional epithelium ...
... they lead to a variable degree of alveolar bone resorption. Raloxifene is an agonist in bone, and acts inhibiting bone loss. ... Alveolar bone volume reduction may interfere with the success of oral rehabilitation treatments. Therefore, loss of this bone ... Bone loss analysis. Bone loss was measured by a single blind, calibrated examiner using image analysis software (Image Tool, ... Bone loss did not vary significantly when EG and CG were compared (Figure 2). Bone loss was observed (CG vs. EG, respectively) ...
I believe it can also cause alveolar bone loss which is causing more space at the base of my teeth. Has anybody had tooth decay ... I believe it can also cause alveolar bone loss which is causing more space at the base of my teeth. Has anybody had tooth decay ...
Clinical parameters improved significantly in both the groups after NSPT (P ≤ 0.05). Alveolar bone loss was greater in ... However, this effect of female sex hormones on periodontal ligament and tooth-supporting alveolar bone has rarely been ... Purpose: Hounsfield unit (HU) provides a quantitative evaluation of bone density. The assessment of bone density is essential ... Background: Oral cancer is known to be governed by the antiapototic and loss of cell adhesion properties which dictate its ...
... alveolar bone resorption and eventually, edentulism. The hosts reaction is orchestrated by proinflammatory cytokines and ... improve clinical outcomes and even prevent tooth loss in severely compromised patients. This work examines the role of pro- ... The host response leads to extracellular matrix (ECM) destruction, loss of attachment, ... The host response leads to extracellular matrix (ECM) destruction, loss of attachment, alveolar bone resorption and eventually ...
... alveolar bone loss, dental prosthesis design, osseointegration, alveolar atrophy. ... Clinical research interests: implant-supported dental prosthesis, endosseous dental implantation, dental implants, alveolar ...
... leads to the loss of tooth-supporting structures and the resorption of the alveolar bone. Since PD and obstructive sleep apnea ... 5 mm and no interproximal alveolar bone loss visible on bitewing radiographs. At baseline, PD patients and non-PD controls ...

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