Alveolar Bone Loss: Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.Alveolar Process: The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth.Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)Tooth Cervix: The constricted part of the tooth at the junction of the crown and root or roots. It is often referred to as the cementoenamel junction (CEJ), the line at which the cementum covering the root of a tooth and the enamel of the tooth meet. (Jablonski, Dictionary of Dentistry, 1992, p530, p433)Bacteroidaceae Infections: Infections with bacteria of the family BACTEROIDACEAE.Maxillary DiseasesBone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Bone Resorption: Bone loss due to osteoclastic activity.Porphyromonas gingivalis: A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.Periodontium: The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Periodontal Ligament: The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).Mandible: The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.Radiography, Bitewing: Technique involving the passage of X-rays through oral structures to create a film record while a central tab or wing of dental X-ray film is being held between upper and lower teeth.Photography, Dental: Photographic techniques used in ORTHODONTICS; DENTAL ESTHETICS; and patient education.Bone Remodeling: The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.Bone Density: The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.Tooth Socket: A hollow part of the alveolar process of the MAXILLA or MANDIBLE where each tooth fits and is attached via the periodontal ligament.Actinobacillus Infections: Infections with bacteria of the genus ACTINOBACILLUS.Aggregatibacter actinomycetemcomitans: A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.Periodontal Pocket: An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.Chronic Periodontitis: Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.Maxilla: One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.Macrophages, Alveolar: Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.Alveoloplasty: Conservative contouring of the alveolar process, in preparation for immediate or future denture construction. (Dorland, 28th ed)Gingiva: Oral tissue surrounding and attached to TEETH.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.RANK Ligand: A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.Ligation: Application of a ligature to tie a vessel or strangulate a part.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Random Allocation: A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.Bone Regeneration: Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.Pulmonary Alveoli: Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.Tooth Movement: Orthodontic techniques used to correct the malposition of a single tooth.Osteonectin: Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.Tooth Eruption: The emergence of a tooth from within its follicle in the ALVEOLAR PROCESS of the MAXILLA or MANDIBLE into the ORAL CAVITY. (Boucher's Clinical Dental Terminology, 4th ed)Molar: The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821)Osteoclasts: A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.Dental Cementum: The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992)Bone Diseases, MetabolicBone Development: The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.X-Ray Microtomography: X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.Bone Matrix: Extracellular substance of bone tissue consisting of COLLAGEN fibers, ground substance, and inorganic crystalline minerals and salts.Bone Marrow: The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.Alveolar Bone Grafting: Surgical procedure to add bone to the ALVEOLAR RIDGE in children born with a CLEFT LIP and a CLEFT PALATE.Osteogenesis: The process of bone formation. Histogenesis of bone including ossification.Bone Transplantation: The grafting of bone from a donor site to a recipient site.Bone Diseases: Diseases of BONES.Bone Marrow Cells: Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Tooth: One of a set of bone-like structures in the mouth used for biting and chewing.Tooth Extraction: The surgical removal of a tooth. (Dorland, 28th ed)Osteoblasts: Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.Radiography, Dental: Radiographic techniques used in dentistry.Tooth Root: The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)Periodontal Attachment Loss: Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.Mandibular DiseasesTooth Mobility: Horizontal and, to a lesser degree, axial movement of a tooth in response to normal forces, as in occlusion. It refers also to the movability of a tooth resulting from loss of all or a portion of its attachment and supportive apparatus, as seen in periodontitis, occlusal trauma, and periodontosis. (From Jablonski, Dictionary of Dentistry, 1992, p507 & Boucher's Clinical Dental Terminology, 4th ed, p313)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Dental Implants: Biocompatible materials placed into (endosseous) or onto (subperiosteal) the jawbone to support a crown, bridge, or artificial tooth, or to stabilize a diseased tooth.Pulmonary Alveolar Proteinosis: A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.Femur: The longest and largest bone of the skeleton, it is situated between the hip and the knee.
Morphological changes in periodontal mechanoreceptors of mouse maxillary incisors after the experimental induction of anterior crossbite: a light and electron microscopic observation using immunohistochemistry for PGP 9.5. (1/419)
Ruffini nerve endings (mechanoreceptors) in the periodontal ligament (PDL) of mouse incisors were examined to elucidate whether experimentally-induced crossbites cause any changes or abnormalities in their morphology and distribution. Anterior guiding planes were attached to the mandibular incisors of 3-week-old C3H/HeSlc mice. At 3 days and 1, 2, 4, 6, and 8 weeks post-attachment of the appliance, the mice were sacrificed by perfusion fixation. Frozen sagittal cryostat sections of the decalcified maxillary incisors were processed for immunohistochemistry of protein gene product 9.5, followed by histochemical determination of tartrate-resistant acid phosphatase activity to reveal sites of alveolar bone resorption. Despite the absence of bone resorption within the lingual PDL of control mice, distinct resorption sites were seen in the respective regions of the experimental animals. Unlike the controls, many Ruffini endings showing vague and swollen contours, with unusually long and pedunculated micro-projections were observed in the affected lingual PDL of the incisors in the experimental animals with short-term anterior crossbite induction. Club-shaped nerve terminations with few, if any, micro-projections were observed in the lingual PDL of experimental animals with long-term induction, as well as in aged control mouse incisors. Differences in the distribution of Ruffini endings were also observed. These results indicate that changing the direction of the force applied to the PDL results in rapid and prolonged changes in the morphology of Ruffini-like mechanoreceptors. (+info)Histological and histochemical quantification of root resorption incident to the application of intrusive force to rat molars. (2/419)
This study was conducted to investigate the nature of root resorption resulting from intrusive forces applied to the rat lower molars, by means of histological and histochemical techniques with tartrate resistant acid phosphatase (TRAP). Thirty-eight 13-week-old Wistar strain male rats were used. Intrusive force was created by a fixed appliance which was adjusted to exert an initial force of 50 g for the duration of 1, 2, and 3 weeks. The degree of root resorption and distribution of TRAP positive cells were evaluated. On the root surface, the TRAP positive scores were low in the apical regions. Significant differences in the scores were found in the inter-radicular region of the roots between the experimental and control groups for the 2- and 3-week groups. More active resorption of bone occurred during the experimental period, as denoted by greater TRAP positive scores on the bone than on the root surface. Root resorption scores in the apical root region were larger in the 2- and 3-week groups than in the 1-week group. Significant differences in the root resorption scores were also found between the 1- and 3-week groups in the inter-radicular region, indicating that intrusive force application of a longer duration may lead to a higher frequency of root resorption. It is shown that, irrespective of the level of TRAP positive cells and root resorption scores, the degree of root resorption activity is higher in the apical root region than in the inter-radicular area. These results indicate that cellular cementum may be resorbed more easily because of its richer organic components and low mineralized structure. (+info)Host modulation as a therapeutic strategy in the treatment of periodontal disease. (3/419)
Specific microorganisms initiate the immunoinflammatory processes that destroy tissue in periodontitis. Recent work has demonstrated, in addition to bacterial control, that modulation of the host immunoinflammatory response is also capable of controlling periodontitis. Matrix metalloproteinases (MMPs) destroy collagen and other matrix components, and the osteoclastic bone remodeling determines the periodontal bone response to a bacterial challenge. Other components of the biology, including cytokines and prostanoids, regulate MMPs and bone remodeling and are also involved in regulating the production of defensive elements, such as antibody. Agents directed at blocking MMPs or osteoclastic activity are effective in reducing periodontitis. Agents that inhibit prostaglandin E2 and selective blockage of specific cytokines have also been effective. Improved knowledge of bacterium-host interactions and of the processes leading to tissue destruction will help to identify targets for host modulation to reduce periodontitis in selected situations. (+info)CD4(+) T cells and the proinflammatory cytokines gamma interferon and interleukin-6 contribute to alveolar bone loss in mice. (4/419)
In this study, we used a mouse model to examine the role of the adaptive immune response in alveolar bone loss induced by oral infection with the human gram-negative anaerobic bacterium Porphyromonas gingivalis. Severe combined immunodeficient mice, which lack B and T lymphocytes, exhibited considerably less bone loss than did immunocompetent mice after oral infection, suggesting that lymphocytes contribute to this process. Bone loss after oral infection was decreased in mice deficient in major histocompatibility complex (MHC) class II-responsive CD4(+) T cells, but no change in bone loss was observed in mice deficient in MHC class I-responsive CD8(+) T cells or NK1(+) T cells. Mice lacking the cytokine gamma interferon or interleukin-6 also demonstrated decreased bone loss. These results suggest that the adaptive immune response, and in particular CD4(+) T cells and the proinflammatory cytokines that they secrete, are important effectors of bone loss consequent to P. gingivalis oral infection. The studies also reinforce the utility of the mouse oral infection model in dissecting the pathobiology of periodontal disease. (+info)C-telopeptide pyridinoline cross-links. Sensitive indicators of periodontal tissue destruction. (5/419)
C-telopeptides and related pyridinoline cross-links of bone Type I collagen are sensitive markers of bone resorption in osteolytic diseases such as osteoporosis and osteoarthritis. We have studied the release of C-telopeptide pyridinoline crosslinks of Type I collagen as measures of bone destruction in periodontal disease. Studies in preclinical animal models and humans have demonstrated the relationship between radiographic bone loss and crevicular fluid C-telopeptide levels. We have recently found that C-telopeptide levels correlate strongly with microbial pathogens associated with periodontitis and around endosseous dental implants. Host-modulation of bone-related collagen breakdown has been shown by studies in humans demonstrating that MMP inhibition blocks tissue destruction and release of C-telopeptides in patients with active periodontal disease. (+info)Host responses to recombinant hemagglutinin B of Porphyromonas gingivalis in an experimental rat model. (6/419)
Porphyromonas gingivalis, a gram-negative, black-pigmented anaerobe, is among the microorganisms implicated in the etiology of adult periodontal disease. This bacterium possesses a number of factors, including hemagglutinins, of potential importance in virulence. Several hemagglutinin genes have been identified, cloned, and expressed in Escherichia coli. The purpose of this study was to characterize host responses to purified recombinant hemagglutinin B (rHag B), using the conventional Fischer rat as the experimental animal model. The effectiveness of immunization with rHag B on protection against experimental periodontal bone loss following infection with P. gingivalis was also evaluated. Groups of rats were immunized by the subcutaneous route with rHag B in complete Freund's adjuvant, immunized with rHag B and orally infected with P. gingivalis, nonimmunized and noninfected, or orally infected with P. gingivalis only. Serum and saliva samples were collected throughout the experiment and evaluated for serum immunoglobulin G (IgG) and IgM and salivary IgA antibody activity by enzyme-linked immunosorbent assay. No salivary IgA anti-Hag B activity was detected in the various groups of rats. A slight serum IgM response similar to that seen in preimmune samples was observed. Serum IgG antibody activity to Hag B was detected only in samples from rats immunized with rHag B. This response was primarily of the IgG1 and IgG2a subclasses, followed by IgG2b and low levels of IgG2c. Supernatants from rHag B-stimulated splenic lymphoid cell cultures from immunized rats contained high levels of gamma interferon, followed by interleukin-2 (IL-2), IL-10, and then IL-4. These results are consistent with the induction of T helper type 1 (Th1)- and Th2-like responses. Western blot analysis of sera derived from rHag B-immunized rats reacted with trichloroacetic acid (TCA) precipitates of P. gingivalis 33277, 381, A7A1-28, and W50, revealing a 50-kDa band reflective of Hag B. However, sera derived from rats immunized with P. gingivalis whole cells or from rats infected with P. gingivalis only did not react with rHag B but did react with TCA precipitates of P. gingivalis strains. Finally, radiographic measurements of periodontal bone loss indicated that rats immunized with rHag B had less bone loss than those infected with P. gingivalis only. These results demonstrate the effectiveness of purified rHag B in inducing a protective immune response and support the potential usefulness of this component of P. gingivalis in the development of a vaccine against adult periodontitis. (+info)Requirement of B7 costimulation for Th1-mediated inflammatory bone resorption in experimental periodontal disease. (7/419)
The CD28 costimulation at TCR signaling plays a pivotal role in the regulation of the T cell response. To elucidate the role of T cells in periodontal disease, a system of cell transfer with TCR/CD28-dependent Th1 or Th2 clones was developed in rats. Gingival injection of specific Ag, Actinobacillus actinomycetemcomitans 29-kDa outer membrane protein, and LPS could induce local bone resorption 10 days after the transfer of Ag-specific Th1 clone cells, but not after transfer of Th2 clone cells. Interestingly, the presence of LPS was required not only for the induction of bone resorption but also for Ag-specific IgG2a production. LPS injection elicited the induction of expression of both B7-1 and B7-2 expression on gingival macrophages, which otherwise expressed only MHC class II when animals were injected with Ag alone. The expression of B7 molecules was observed for up to 3 days, which corresponded to the duration of retention of T clone cells in gingival tissues. Either local or systemic administration of CTLA4Ig, a functional antagonist of CD28 binding to B7, could abrogate the bone resorption induced by Th1 clone cells combined with gingival challenge with both Ag and LPS. These results suggest that local Ag-specific activation of Th1-type T cells by B7 costimulation appeared to trigger inflammatory bone resorption, whereas inhibition of B7 expression by CTLA4Ig might be a therapeutic approach for intervention with inflammatory bone resorption. (+info)Long-term follow-up of maxillary incisors with severe apical root resorption. (8/419)
The purpose of the study was to analyse the mobility of teeth with severe orthodontically induced root resorption, at follow-up several years after active treatment, and to evaluate mobility in relation to root length and alveolar bone support. Seventy-three maxillary incisors were examined in 20 patients, 10-15 years after active treatment in 13 patients (age 24-32 years) and 5-10 years after active treatment in seven patients (age 20-25 years). All had worn fixed or removable retainers; seven still had bonded twistflex retainers. Total root length and intra-alveolar root length were measured on intra-oral radiographs. Tooth mobility was assessed clinically according to Miller's Index (0-4) and the Periotest method. Crestal alveolar bone level, periodontal pocket depth, gingival, and plaque indices, occlusal contacts during occlusion and function, and dental wear were recorded. There was a significant correlation (P < 0.05) between tooth mobility, and total root length and intra-alveolar root length. No correlation was found between tooth mobility and retention with twistflex retainers. None of the variables for assessment of periodontal status, occlusion and function were related to total root length or tooth mobility. It is concluded that there is a risk of tooth mobility in a maxillary incisor that undergoes severe root resorption during orthodontic treatment, if the remaining total root length is < or = 9 mm. The risk is less if the remaining root length is > 9 mm. Follow-up of teeth with severe orthodontically induced root resorption is indicated. (+info)... involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening ... Zadik Y, Bechor R, Shochat Z, Galor S; Bechor; Shochat; Galor (April 2008). "Ethnic origin and alveolar bone loss in Israeli ... of attachment loss Moderate: 3-4 mm (0.12-0.16 in) of attachment loss Severe: ≥ 5 mm (0.20 in) of attachment loss In the early ... periodontal surgery may be needed to stop progressive bone loss and regenerate lost bone where possible. Many surgical ...
Untreated, these diseases lead to alveolar bone loss and tooth loss. As of 2017[update], these continue to be one of the ... The supporting tissues are known as the periodontium, which includes the gingiva (gums), alveolar bone, cementum, and the ... including the treatment of peri-implantitis which is inflammatory bone loss around dental implants. The etiology of peri- ... combined with host immuno-inflammatory mechanisms and other risk factors which lead to destruction of the supporting bone ...
"Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice". Journal of Bone and Mineral Research. doi: ... "A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone ...
ISBN 81-89093-10-X. Liran, Levin (June 2007). "Alveolar Bone Loss and Gingival Recession Due to Lip and Tongue Piercing". N Y ... In some cases, the alveolar tooth-bearing bone is also involved, jeopardizing the stability and durability of the teeth in ... Bone, Angie; Fortune Ncube; Tom Nichols; Norman D Noah (21 June 2008). "Body Piercing in England: a Survey of Piercing at Sites ... It was popular among the Aztecs, the Mayans and the tribes of New Guinea, who adorned their pierced noses with bones and ...
Extension of the lesion into alveolar bone, periodontal ligament with significant bone loss Continued loss of collagen ... The disease consists of a chronic inflammation associated with loss of alveolar bone. Advanced disease features include pus and ... drifting and eventual loss Because bone loss makes its first appearance in the advanced lesion, it is equated with ... Features of the Established Lesion: Predominance of plasma cells without bone loss Presence of extravascular immunoglobulins in ...
This may further lead to furcal involvement through loss of clinical attachment and alveolar bone. A cursory clinical ... This is because neutrophils, which are rich sources of PGE2, are present when the majority of rapid bone loss occurs during the ... injured site and cause resorption of the periapical alveolar bone. It is possible that after conventional endodontic therapy ... Regeneration of the bone has been demonstrated to occur, on average, at a rate of 3.2 mm² per month, and studies suggest that ...
... is a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. ... Alveolar bone is the bone that surrounds the roots of the teeth forming bone sockets. In mammals, tooth sockets are found in ... Polyphyodont Alveolar ridge Peck, Mogammad Thabit; Marnewick, Johan; Stephen, Lawrence (2011). "Alveolar Ridge Preservation ... Dental alveoli (singular alveolus) are sockets in the jaws in which the roots of teeth are held in the alveolar process with ...
In advanced cases the alveolar bone loss may be depicted as a horizontal bone loss pattern radiographically. Mostly in ... Loss of attachment refers to the destruction of periodontium whereas the bone refers to the alveolar bone supporting the teeth ... "Five-year alveolar bone level changes in women of varying skeletal bone mineral density and bone trabeculation". Oral Surgery, ... to the alveolar bone crest is typically in the order of 1mm in young people. If the distance between the ACJ and alveolar bone ...
This condition increase alveolar bone loss, attachment loss, tooth mobility, and finally tooth loss (McGuire &Nunn, 1996). It ... involvement in bone infections: a review. Int J Antimicrob Agents. 2013 Jun;41(6):509-15. Rogers MB, Parker AC, Smith CJ. 1993 ...
Untreated, these diseases can lead to alveolar bone loss and tooth loss. As of 2013[update], Periodontal disease accounted for ... Alveolar Bone[edit]. In periodontal health, the alveolar bone surrounds the teeth and forms the bony socket that supports each ... ongoing chronic stress are more likely to have clinical attachment loss and decreased levels of alveolar bone due to ... Alveolar bone D. Oral epithelium E. Attached gingiva F. Gingival margin G. Gingival sulcus H. Junctional epithelium I. Alveolar ...
Stippling only presents on the attached gingiva bound to underlying alveolar bone, not the freely moveable alveolar mucosa. ... unless it is smooth due to a loss of previously existing stippling. Stippling is a consequence of the microscopic elevations ...
Effect of dietary vitamin E supplement and rotational stress on alveolar bone loss in rice rats (subscription required). ... Effect of stannous fluoride and iodine on root caries and bone loss in rats. Ohio Journal of Science 88(3):99-100. Benson, D.E ... Vitamin E, fluoride, and iodide protect against bone loss associated with this disease in the rice rat and a high-sucrose diet ... The nasal and premaxillary bones extend back beyond the point where the lacrimal, frontal, and maxillary bones meet. In P. o. ...
They describe the development of lateral plates on the alveolar margins of tooth-bearing bones. These plates can be used to ... strip foliage, the eusauropod's "U-shaped" jaws create a wide bite, and their loss of "fleshy cheeks" increased the gape. The ... Unlike prosauropods and theropods, which have a snout with smooth, unprotruding alveolar and subnarial regions, eusauropods ...
Interproximal and horizontal alveolar bone loss in mouse models are seen in coinfections involving P. gingivalis and Treponema ... Vaccines made from P. gingivalis CPS apparently impair oral bone loss in murine models. These vaccines have been able to elicit ... In contrast, germ free mice inoculated with a P. gingivalis monoinfection incur no bone loss, indicating that P. gingivalis ... In these models, P. gingivalis inoculation causes significant bone loss, which is a significant characteristic of the disease. ...
... a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. A ... PRF is used in guided bone and tissue regeneration PRF enhances alveolar bone augmentation and necrotic dental pulp and open ... "Platelet-Rich Fibrin Promotes Periodontal Regeneration and Enhances Alveolar Bone Augmentation". BioMed Research International ... platelet-rich fibrin (PRF) membrane containing bone growth enhancing elements can be stitched over the wound or a graft ...
"Acemannan sponges stimulate alveolar bone, cementum and periodontal ligament regeneration in a canine class II furcation defect ... this approach might provide some advantages in treatment of both cartilage and bone loss. The IVB concept needs to be however ... Upon exposure of the periosteal cells to calcium from the alginate gel, these cells become bone cells and start producing bone ... CS1 maint: Uses authors parameter (link) Bai M., Zhang T., Ling T., Zhou Z., Xie H., Zhang W., Wu H. (2013). "Guided bone ...
They are also attached to the gingival (gum) tissue that covers the alveolar bone by an attachment apparatus; because this ... Teeth are attached to the surrounding and supporting alveolar bone by periodontal ligament (PDL) fibers; these fibers run from ... Although this is technically a loss of clinical attachment, the term clinical attachment loss is used almost exclusively to ... of the alveolar bone, it is termed the supracrestal attachment apparatus. The supracrestal attachment apparatus is composed of ...
... a fracture of the alveolar process of the upper jaw bone which caused severe neurities [sic] with persistent neuralgic pain ... both day and night ... likewise causing the loss of all the teeth of the upper jaw on one side of the face." In 1914 she ...
A suprabony pocket occurs when there is horizontal bone loss, the bottom of the pocket is coronal to the alveolar bone. An ... infrabony pocket occurs when there is vertical bone loss where the bottom of the pocket is apical to the alveolar bone. ... pockets can cause the loosening and loss of dentition due to destruction of supporting tissues including the alveolar bone, PDL ... loss are considered pseudopockets.There are two types of periodontal pockets that are determined by the type of bone loss ...
If the tooth has pre-existing periodontal disease, with pockets and loss of alveolar bone height, it is more likely to be a ... The path of the infection is influenced by such things as the location of the infected tooth and the thickness of the bone, ... If left untreated, a severe tooth abscess may become large enough to perforate bone and extend into the soft tissue eventually ... In some cases, a tooth abscess may perforate bone and start draining into the surrounding tissues creating local facial ...
Loss of teeth alters the form of the alveolar bone in 91% of cases. In addition to this resorption of bone in the vertical and ... bone loss, presenting with a distal horizontal defect and a mesial vertical defect. Tooth #22 exhibits roughly 30% bone loss. ... The alveolar bone is unique in that it exists for the sake of the teeth that it retains; when the teeth are absent, the bone ... Bone loss with missing teeth, partials and complete dentures is progressive. According to Wolff's law, bone is stimulated, ...
This condition increase alveolar bone loss, attachment loss, tooth mobility, and finally tooth loss.[4] It can cause other ... involvement in bone infections: a review. Int J Antimicrob Agents. 2013 Jun;41(6):509-15. ...
In cases where recession is not accompanied by periodontal bone loss, complete or near complete coverage of the recession area ... It may exist with or without concomitant decrease in crown-to-root ratio (recession of alveolar bone). Various classifications ... Gingival recession, also known as receding gums, is the exposure in the roots of the teeth caused by a loss of gum tissue and/ ... This material is usually combined with the cellular matrix to form a soft bone paste that is then covered by the allograft. The ...
Depths greater than 3 mm can be associated with "attachment loss" of the tooth to the surrounding alveolar bone, which is a ...
... implants exhibited less-than-expected initial crestal bone loss-the effect of bone modeling at the crest of the alveolar bone ... "bone loss to the first thread." This vertical loss of bone (X in the diagram at right) diminishes the bone-to-implant contact, ... the lateral extent of this vertical bone loss around implants has been investigated-in other words, the thickness of bone loss ... allowing for a reduction in the horizontal extent of bone loss. Canullo L, et al. Platform switching and marginal bone-level ...
"Bone Marrow Transplant" redirects here. For the journal abbreviated Bone Marrow Transplant, see Bone Marrow Transplantation ( ... In the case of allogeneic transplants, fresh HSC are preferred in order to avoid cell loss that might occur during the freezing ... alveolar hemorrhage, and allergic reactions (usually expressed in first 30 minutes, risk 1 in 300).[43][44][45] In addition, ... In the case of a bone marrow transplant, the HSC are removed from a large bone of the donor, typically the pelvis, through a ...
Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar ... Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar ... Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar ... Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar ...
... were subjected to quantitative radiographic evaluation of alveolar bone loss and tooth loss. There was a high prevalence of ... A significant positive interaction between alveolar bone loss and tooth loss (P < 0.01), implies that the highly prevalent ... were subjected to quantitative radiographic evaluation of alveolar bone loss and tooth loss. There was a high prevalence of ... A significant positive interaction between alveolar bone loss and tooth loss (P < 0.01), implies that the highly prevalent ...
... host immune responses to dysregulated microbiota in dental biofilms leading to degradation of tissues and alveolar bone loss. ...
that the periotest value dependent to a large extent on bone. loss. The greater the alveolar bone height, the lower the. ... 7. Bone factor concept of Glickman: When a generalized. tendency toward bone resorption exists, bone loss initiated. by local ... systemic influence on the response of alveolar bone has been. termed the bone factor in periodontal disease. The bone. factor ... 1. Bone loss or loss of tooth support:. 2. Trauma from occlusion:. 3. Hypofunction:. 4. Extension of inflammation from the ...
... periodontitis can lead to progressive loss of the periodontal bone and subsequent tooth loss [2]. The ultimate goal of ... is located between teeth and alveolar bone and plays an integral role in the maintenance and regeneration of periodontal tissue ... Enhanced bone regeneration with a gold nanoparticle-hydrogel complex. J Mater Chem B Mater Biol Med. 2014;2:1584-93 ... J Bone Miner Res. 2013;28:2414-30 24. Li J, Li JJ, Zhang J, Wang X, Kawazoe N, Chen G. Gold nanoparticle size and shape ...
Immune responses to infection trigger loss of alveolar bone from the jaw and eventual tooth loss. We investigated the ... B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection. Pamela J. Baker,1 Nicole Ryan Boutaugh,1 ... contribution of B cell IgD to alveolar bone loss by comparing the response of B cell normal BALB/cJ mice and IgD deficient BALB ... Specific antibody to P. gingivalis was lower and oral colonization was higher in IgD deficient mice; yet bone loss was ...
"Alveolar Bone Loss" by people in Harvard Catalyst Profiles by year, and whether "Alveolar Bone Loss" was a major or minor topic ... Annual alveolar bone loss in older adults taking oral bisphosphonate: a retrospective cohort study. BMC Oral Health. 2019 11 27 ... "Alveolar Bone Loss" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Prevalence of periodontitis and alveolar bone loss in a patient population at Harvard School of Dental Medicine. BMC Oral ...
403 Bis-enoxacin Inhibited Alveolar Bone Loss and Gingival Inflammation in Rats Thursday, March 22, 2012: 2 p.m. - 3:15 p.m. ... and alendronate in inhibiting osteoclast alveolar bone resorption (ABR) in a polymicrobial periodontal disease rat model. ... Similarly, enoxacin-linked bisphosphonate, bis-enoxacin, inhibits osteoclast formation and bone resorption. Periodontal ...
Quantify periodontal alveolar bone loss rates in postmenopausal women.. II. Evaluate the effects of estrogen on alveolar bone ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. The safety and ... Comparison of reliability of manual and computer-intensive methods for radiodensity measures of alveolar bone loss. ... loss rates in these patients.. III. Determine whether changes in periodontal bone mass relate to bone mass changes in other ...
Quantify periodontal alveolar bone loss rates in postmenopausal women.. II. Evaluate the effects of estrogen on alveolar bone ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. The safety and ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. ... Comparison of reliability of manual and computer-intensive methods for radiodensity measures of alveolar bone loss. ...
... severe alveolar bone loss ranging between 1/3 and 2/3 of the normal alveolar bone height (group 4), or alveolar bone loss ... gingivitis without signs of alveolar bone loss (group 2), moderate alveolar bone loss not exceeding 1/3 of the normal alveolar ... Mean alveolar bone loss varied between 1.51 mm and 2.64 mm depending on smoking status and age. Mean alveolar bone loss was ... Alveolar bone loss was recorded if the distance from the cemento-enamel junction to the alveolar crest exceeded 2 mm measured ...
Effect of Ratio of Residual Alveolar Bone to Graft Material in Contact With Fixture Surface on Marginal Bone Loss of Implants ... The residual bone/implant length ratio and the residual bone/implant area ratio were not associated with marginal bone loss at ... The residual bone/implant length ratio and residual bone/implant area ratio were not associated with marginal bone loss around ... study was to evaluate the influences of height or area ratio of residual alveolar bone to graft material on marginal bone loss ...
... ... as well as severe hypertension and alveolar bone loss (ABL) in older adults. ... Direct measures of alveolar bone level were recorded using CT scans, and different variables were studied (age, sex, Plaque ... The results confirmed a positive association between CHD/VD and periodontal destruction; alveolar bone destruction represented ...
... Grethe Jonasson, Marianne Rythén*Clinical Cosmetic and ...
Morphometric registration of alveolar bone loss was carried out after 30 days of ligature placement to determine the effect of ... Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental ... Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental ... Effect of obesity on alveolar bone loss in experimental periodontitis in Wistar rats. ...
Nakano, M. (2009). Idiopathic external root resorption with alveolar bone loss: Case report and microbiological evaluation. ... Nakano, M 2009, Idiopathic external root resorption with alveolar bone loss: Case report and microbiological evaluation, ... Idiopathic external root resorption with alveolar bone loss: Case report and microbiological evaluation. / Nakano, Michiyo. ... Idiopathic external root resorption with alveolar bone loss: Case report and microbiological evaluation. In: Pediatric Dental ...
Alveolar bone loss • Alveolar bone levels are evaluated by clinical and radiographic examination. • Probing is helpful for ... The periodontal pocket is a soft tissue change • Radiographs indicate areas of bone loss where pockets may be suspected but : 1 ... Changes in the level of attachment can be due only to gain or loss of attachment and afford a better indication of the degree ... If both are the same, the loss of attachment is zero • When the gingival margin coincides with the cementoenamel junction, the ...
Results: The measurements of alveolar bone loss in the mandibular molars revealed significantly higher bone-loss values in the ... Alveolar bone loss was measured. Interleukin 1 beta (IL-1 beta) and interleukin 10 (IL-10) were evaluated in the serum samples ... The aim of this study was to evaluate the effects of systemic curcumin therapy on alveolar bone loss in an experimental ... Effects of Curcumin on Alveolar Bone Loss in Experimental Periodontitis in Rats: A Morphometric and Histopathologic Study ...
The polymicrobial infection triggered significant alveolar bone loss, a heightened antibody response, an elevated cytokine ... Associations were found between bone loss, specific viral and bacterial species, immune genes, and PDL space changes. These ... Although bacterially-mediated mechanisms of alveolar bone destruction have been widely studied, the effects of a polymicrobial ... changes in bone loss, the host immune response, and the microbiome/virome using shotgun sequencing. Periodontal pathogens, ...
Alveolar Bone Loss. *Bad Taste in Mouth. *Black Hairy Tongue. *Bonding Disorders ...
Alveolar Bone Loss. *Anodontia. *Bad Taste in Mouth. *Bleeding Gums. *Bonding Disorders ...
Bone Loss, Alveolar Tooth Loss Bone Atrophy, Alveolar Procedure: AUTOTRANSPLANTATION TOOTH Not Applicable ... Alveolar Bone Loss. Tooth Loss. Atrophy. Pathological Conditions, Anatomical. Periodontal Diseases. Mouth Diseases. ... Change in alveolar bone 12 months after tooth autotransplantation [ Time Frame: 1 year ]. CT-scan evaluation before surgery and ... Tooth Autotransplantation and Bone Dimension Changes. The safety and scientific validity of this study is the responsibility of ...
... the periodontal ligament and alveolar bone). It is highly prevalent... ... pattern of bone loss. Some of the teeth have lost nearly all their supporting alveolar bone as a result of periodontitis ... Alveolar bone levels are normal, with the crest of the alveolar bone being in close proximity to the cemento-enamel junction ( ... Risk indicators for alveolar bone loss. J Periodontol 66:23-29PubMedCrossRefGoogle Scholar ...
Alveolar ridge preservation (ARP) has been shown to prevent postextraction bone loss. The aim of this report is to highlight ... Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft. Andreas O. Parashis,1,2 Charalampos J. ... The XCM was adapted to cover the defect and 2-3 mm of adjacent bone and flaps were repositioned. Healing was uneventful in all ... Radiographic and clinical assessment indicated adequate volume of bone for implant placement, with all planned implants placed ...
Animals , Male , Alveolar Bone Loss/pathology , Periodontitis/etiology , Periodontitis/pathology , Alveolar Bone Loss/ ... and kinetics of the alveolar bone-loss measurement methodologies i Agreement, correlation, and kinetics of the alveolar bone- ... Full text: Available Index: LILACS (Americas) Main subject: Periodontitis / Alveolar Bone Loss Type of study: Evaluation ... Full text: Available Index: LILACS (Americas) Main subject: Periodontitis / Alveolar Bone Loss Type of study: Evaluation ...
PeriodontitisRegenerationGraftsTeethMarrow-derived mesenchymal stemMolarsPeriodontal tissuePeriodontitisConnectiveRadiographic alveolar boneAtrophyGingivitisEdentulous Alveolar RidgeTissueAttachment lossInflammationPostmenopausal womenGumsEtiologyRadiographsRatsMeSHInflammatoryLeft untreatedSevereDeeper periodontalLesionsOsteoclastMarrowPrevalenceMorphometricImmuneEnamelProgressionPosterior regionEvaluateDiseasesExperimentalCollagenBuccalInfectionLeads to tooth lossOral bone lossStudySalivaryAnatomicalCurcumin
- Periodontitis is a lesser known but frequent complication of diabetes mellitus and is the major cause of tooth loss in patients with diabetes. (nebraska.edu)
- If left untreated, periodontitis can lead to progressive loss of the periodontal bone and subsequent tooth loss [ 2 ]. (thno.org)
- These findings revealed that AuNPs affected the osteogenic differentiation of PDLPs in a size-dependent manner with autophagy as a potential explanation, which suggested AuNPs with defined size could be a promising material for periodontal bone regeneration. (thno.org)
- The ultimate goal of periodontal therapy is to achieve periodontal tissue regeneration, in which bone tissue regeneration is a crucial part [ 3 ]. (thno.org)
- The periodontal ligament (PDL) is located between teeth and alveolar bone and plays an integral role in the maintenance and regeneration of periodontal tissue. (thno.org)
- As seen in ankylosed tooth after failing replantation or if autogenous bone grafts are placed in contact with detached root surface. (scribd.com)
- Four teeth in one half of the mandible (P3, P4, M1, M2) were subjected to quantitative radiographic evaluation of alveolar bone loss and tooth loss. (dtu.dk)
- Severe periodontal disease (defined by more than 50% bone loss related to one or more teeth) was not detected in mink aged 7 mo, but affected 15.3% of mink aged 19 mo and 39.6% of mink aged 31 mo. (dtu.dk)
- 11 ] showed that AuNPs facilitated the differentiation of bone marrow-derived mesenchymal stem cells (MSCs) towards osteoblast over adipocytes through activating the p38 MAPK signaling pathway. (thno.org)
- Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar bone on the 2 molars between which the injections were made, and by measuring the ratio of root area/enamel area in the same region. (nebraska.edu)
- Periodontal ligament progenitor cells (PDLPs), with stem-cell-like properties, exhibit great potential for repair periodontal tissue including the formation of new bone [ 5 , 6 ]. (thno.org)
- Prevalence of periodontitis and alveolar bone loss in a patient population at Harvard School of Dental Medicine. (harvard.edu)
- Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental periodontitis in rats. (ufrgs.br)
- Conclusions: In spite of the weak differences, it is possible to conclude that the progression of alveolar bone loss in ligature-induced periodontitis can be potentially influenced by body weight in rats. (ufrgs.br)
- Periodontitis is a lesser known but frequent complication of diabetes mellitus and is the major cause of tooth loss in patients with diabetes. (nebraska.edu)
- The aim of this study was to evaluate the effects of systemic curcumin therapy on alveolar bone loss in an experimental periodontitis model in rats. (cumhuriyet.edu.tr)
- Periodontitis is a common chronic inflammatory disease characterised by destruction of the supporting structures of the teeth (the periodontal ligament and alveolar bone). (springer.com)
- Periodontal diseases include gingivitis (in which the inflammation is confined to the gingiva, and is reversible with good oral hygiene) and periodontitis (in which the inflammation extends and results in tissue destruction and alveolar bone resorption). (springer.com)
- Currently, ligature -induced periodontitis in rats is the main model used in periodontal research , in this model, alveolar bone loss (ABL) is the main parameter evaluated by radiographic, morphometric, and histological techniques . (bvsalud.org)
- Advanced periodontitis can cause damage to the gums, the alveolar bone, and other supportive connective tissue. (prweb.com)
- Periodontitis is an inflammatory disease triggered by a microbial dysbiosis that affects the supporting tissues around teeth and it eventually leads to tooth loss if left untreated. (nature.com)
- Conversely, anti-inflammatory treatments in animal models of periodontitis were shown to diminish the periodontal bacterial load, in addition to protecting from bone loss. (nih.gov)
- The authors used these mixed-effects linear models to calculate the progression of periodontitis (the sum of maximum pocket depths and number of teeth with alveolar bone loss) in each arch. (ada.org)
- Patients with aggressive periodontitis (AP) can undergo orthodontic treatment without added attachment loss, according to a study published in the April issue of American Journal of Orthodontics & Dentofacial Orthopedics. (ada.org)
- This gingivitis associated with bleeding of the gums, can progress to periodontitis when soft tissue attachment loss and/or supporting bone loss is seen. (igi-global.com)
- Anti-inflammatory effect of rosuvastatin decreases alveolar bone loss in experimental periodontitis. (nih.gov)
- Periodontitis is a common human chronic inflammatory disease that results in the destruction of the tooth attachment apparatus and tooth loss. (pubmedcentralcanada.ca)
- Using an oral infection periodontitis model we demonstrate that following F. nucleatum infection no alveolar bone loss is observed in mice deficient for NCR1 expression, whereas around 20% bone loss is observed in wild type mice and in mice infected with P. gingivalis . (pubmedcentralcanada.ca)
- Extra circumstances in which transplantation can be careful include tooth agenesis (particularly of premolars and lateral incisors), shocking tooth loss, atopic outbreak of canines, root resorption , large endodontic lesions, cervical root fractures , localized juvenile periodontitis as well as other pathologies. (omicsonline.org)
- In another study, it reduced alveolar bone loss in rats with ligature-induced periodontitis. (medscape.com)
- To test its effects on humans with chronic periodontitis, the researchers recruited 50 male smokers with sites of probing depths of at least 5 mm, clinical attachment levels of at least 4 mm, and vertical bone loss of at least 3 mm. (medscape.com)
- To investigate the effect of oligodeoxynucleotides (ODNs) on the differentiation of rat bone marrow mesenchymal stem cells (BMSCs) to osteoblasts, in order to find a candidate ODN with potential for the treatment of periodontitis, a series of ODNs were designed and selected to test their effect on the promotion of the differentiation of BMSCs to osteoblasts in vitro and on the repair of periodontal tissue in rats with periodontitis. (mdpi.com)
- In vivo study showed that MT01 prevented the loss of alveolar bone in the rats with periodontitis and induced the production of proteins of OPG and Osterix in the bone tissue. (mdpi.com)
- These results indicated that MT01 could induce differentiation of BMSCs to osteoblasts and inhibit the alveolar bone absorption in rats with periodontitis. (mdpi.com)
- 2003) 18 studied ALP activity in serum from patients with chronic periodontitis and showed a relationship between loss of attachment in periodontal disease and ALP activity in serum. (ispub.com)
- Periodontitis, or gum disease, is a common infection that damages the soft tissue and bone supporting the tooth. (medicalnewstoday.com)
- Untreated periodontitis will eventually result in tooth loss. (medicalnewstoday.com)
- Periodontitis, or gum disease , affects the area around the tooth, including the bone and the gum. (medicalnewstoday.com)
- Periodontitis involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening and subsequent loss of teeth. (wikipedia.org)
- A diagnosis of periodontitis is established by inspecting the soft gum tissues around the teeth with a probe (i.e., a clinical examination) and by evaluating the patient's X-ray films (i.e., a radiographic examination), to determine the amount of bone loss around the teeth. (wikipedia.org)
- According to the American Academy of Periodontology, the classification of severity is as follows: Mild: 1-2 mm (0.039-0.079 in) of attachment loss Moderate: 3-4 mm (0.12-0.16 in) of attachment loss Severe: ≥ 5 mm (0.20 in) of attachment loss In the early stages, periodontitis has very few symptoms, and in many individuals the disease has progressed significantly before they seek treatment. (wikipedia.org)
- Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. (bioportfolio.com)
- Stage 3 moderate periodontitis is diagnosed when 25-50 percent support loss occurs. (veterinarypartner.com)
- In Stage 4, advanced periodontitis is greater than 50 percent support loss. (veterinarypartner.com)
- Early Periodontitis Progression of the gingival inflammation into the deeper periodontal structures and alveolar bone crest, with slight bone loss. (studystack.com)
- Moderate Periodontitis A more advanced stage with increased destruction of the periodontal structures and noticeable loss of bone support, possibly accompanied by an increase in tooth mobility. (studystack.com)
- Advanced Periodontitis Further progression of periodontitis with major loss of alveolar bone support usually accompanied by increased tooth mobility. (studystack.com)
- Using the information obtained from this pilot study, we believe, that applying these LIV on an osteoporotic animal model, using different combinations of mechanical loading can provide critical information on the potential treatment modality to prevent oral bone loss caused by diseases such as osteoporosis and periodontitis. (suny.edu)
- The hallmark clinical feature of established periodontitis is attachment loss. (vin.com)
- As periodontitis progresses, alveolar bone is also lost. (vin.com)
- 9 The percent of alveolar bone loss, in conjunction with clinical parameters, is commonly used to determine the presence, degree, and extent of periodontitis. (jdentaled.org)
- Skin lesions are followed by intense gingivitis that rapidly progresses into periodontitis with alveolar bone lysis and early loss of primary dentition. (nih.gov)
- The disease causes inflammation and bleeding of the gingival tissues as a result of the accumulation of microbial dental plaque, and in its destructive form, periodontitis results in progressive destruction of the supporting structures of the teeth leading to looseness of the teeth and ultimately tooth loss. (springer.com)
- Collagen type III-positive connective tissue resembling periodontal ligament and tooth root structures were present at the interface of bioengineered tooth and bone tissues. (mendeley.com)
- There is usually a slight loss of connective tissue attachment and alveolar bone. (studystack.com)
- A band of connective tissue that connects the calf muscle to the heel bone. (harvard.edu)
- To the best of our knowledge, no study has reported radiographic alveolar bone loss (RABL) associated with betel quid chewing. (ncku.edu.tw)
- Low agreement among dentists has been noted in evaluating radiographic alveolar bone levels at implant fixtures. (jdentaled.org)
- Dental radiography shows atrophy of the alveolar bone. (nih.gov)
- 2 The subjects who smoked were shown to be at greater risk for gingivitis, but no differences were noted in bone loss or increased periodontal pocketing. (dentistryiq.com)
- Stage 1 gingivitis occurs when there is inflammation only without loss of the tooth's support. (veterinarypartner.com)
- Lindhe, J: The Edentulous Alveolar Ridge. (wikipedia.org)
- Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. (healthtap.com)
- Early detection of bony and soft tissue support changes is therefore crucial in relation to the prevention of tooth loss and/or the patient's general health. (igi-global.com)
- There must be enough alveolar bone support in all dimensions with sufficient attached keratinized tissue to allow for stabilization of the transplanted tooth. (omicsonline.org)
- We have investigated the utility of a tissue-engineering approach to provide corrective therapies for tooth-bone loss. (mendeley.com)
- 1 reported low agreement among dentists in evaluating study casts for occlusal stability and tissue loss in malocclusion cases. (jdentaled.org)
- Tissue may be rapidly destroyed, risking tooth loss. (merckmanuals.com)
- In healthy gums, the base of the pocket is coincident with the cemento-enamel junction (CEJ, the boundary between the enamel crown and the root) and there is no attachment loss. (springer.com)
- The base of the pocket is therefore apical to the CEJ, and attachment loss can be measured (in mm, using a periodontal probe) from the CEJ to the base of the pocket. (springer.com)
- Examiners blinded to diabetes status performed random half-mouth periodontal examinations, assessing probing depth (PD) and attachment loss (AL) (four sites/tooth) at baseline and follow-up. (diabetesjournals.org)
- ABSTRACT To assess overall and abdominal obesity and their relation to periodontal disease among young adults, body mass index (BMI) and waist circumference (WC) were measured and clinical attachment loss (CAL), gingival index (GI) and Community Periodontal Index (CPI) were estimated. (who.int)
- The inflammation results in the progressive destruction of the periodontal tissues, leading to attachment loss. (vin.com)
- On oral exam, there are two different presentations of attachment loss. (vin.com)
- This condition increase alveolar bone loss, attachment loss, tooth mobility, and finally tooth loss. (wikipedia.org)
- Prevalence and risk indicators for periodontal attachment loss in a population of older community-dwelling blacks and whites. (springer.com)
- Although dysbiosis of the local microbial community initiates local inflammation, over-activation of the host immune response directly activates osteoclastic activity and alveolar bone loss. (nih.gov)
- They found that bone loss in the jaw correlated with the severity of localized inflammation in the joints of the mice. (elsevier.com)
- OBJECTIVES: I. Quantify periodontal alveolar bone loss rates in postmenopausal women. (clinicaltrials.gov)
- BUFFALO, N.Y. -- A study conducted in a large sample of postmenopausal women by University at Buffalo epidemiologists has provided new information on the prevalence of certain gum-disease-causing oral bacteria in this population and the association of the bacteria with oral bone loss. (bio-medicine.org)
- In its mildest form, it can cause inflamed or bleeding gums, while in its severe form, it leads to bone loss, gum recession and even tooth loss. (medindia.net)
- CONCLUSIONS Diabetes control, but not etiology, was associated with future tooth loss and accelerated AL progression. (diabetesjournals.org)
- Alveolar bone loss was measured on bite-wing radiographs. (arctichealth.org)
- A) Incisor and premolar radiographs revealing an overall horizontal breakdown of bone. (igi-global.com)
- 2 The height of the alveolar bone margin and the shape and form of its outline are also examined with radiographs. (ispub.com)
- 3 Biochemical markers can detect inflammatory changes in short period of time where as longer period is required to detect measurable changes in bone density using radiographs. (ispub.com)
- The articdle presents information on a study which investigated bone level changes determined from periapical radiographs made at annual recall visits of patients for up to nine years after implant placement. (ebscohost.com)
- Conclusion: This study demonstrates that systemic administration of curcumin at the 75 and 150mg/kg doses reduced alveolar bone loss in the periodontal disease in rats. (cumhuriyet.edu.tr)
- The aim was to correlate alveolar bone loss in the buccal/palatal and the mesial/distal surfaces of upper molars in rats . (bvsalud.org)
- Alveolar Bone Loss" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
- The infection leads to an inflammatory process which results in the destruction of the dental attachment apparatus associated with tooth loss in adults over the age of 35. (pubmedcentralcanada.ca)
- It is now appreciated that some of the anti-inflammatory actions of ACTH are mediated via the peripheral MC system on MC receptors expressed in bone cells, fibroblasts, and immune cells. (elsevier.com)
- If left untreated, progressive collagen and bone loss can weaken the tooth's anchoring in the alveolar housing and result in tooth loss. (diabetesjournals.org)
- The objective of this study was to utilise a new methodological approach based on radiographic examinations to demonstrate a potential association between coronary heart diseases (CHD) as well as severe hypertension and alveolar bone loss (ABL) in older adults. (ovid.com)
- You won't find an environmental cause for any bone cancer apart from the rare ones that arise in pre-existing severe Paget's of bone, rare genetic syndromes or an old radiation port. (healthtap.com)
- The extent of bone loss was more severe in the ACS group than in the non-ACS group. (eurekalert.org)
- Results showed that women infected with four bacteria known to cause periodontal disease were more likely to have more severe oral bone loss than those without these oral pathogens. (bio-medicine.org)
- Four Cases of Preprosthetic Surgery for Patients with Severe Absorption and/or Loss of the Alveolar Bone. (nii.ac.jp)
- When periodontal disease is not treated, subgingival bacteria can continue to reproduce, potentially creating deeper periodontal pockets through bone destruction. (veterinarypartner.com)
- Other bone lesions when enlarging such as dysplasias or giant cell tumors as preexisting lesions may result in malignant transformation. (healthtap.com)
- What is the cause of lytic bone lesions and hypercalcemia? (healthtap.com)
- Research has shown that activation of MC receptors by ACTH or other MC peptides can lead to a variety of protective actions against bone loss, including increased matrix deposition, reduced osteoclast activation, and enhanced proliferation of bone-forming cells. (elsevier.com)
- Journal Article] Lineage-committed osteoclast precursors circulate in blood and settle down into bone. (nii.ac.jp)
- Increased IgE + B Cells in Sputum, but Not Blood, Bone Marrow, or Tonsils, after Inhaled Allergen Challenge in Subjects with Asthma. (nih.gov)
- Bony mets can cause bony pain ( depending on the location), fractures, spinal cord compression resulting in significant nerve deficits on extremities/weakness/can develop paralysis etc, suppresion to the blood counts if cancer also involves the bone marrow etc. (healthtap.com)
- What causes bone marrow tumors to form? (healthtap.com)
- There are multiple different types of bone marrow tumors and the cause for almost all is unknown. (healthtap.com)
- Bone implants were generated from osteoblasts induced from bone marrow progenitor cells obtained from the same pig, seeded onto PLGA fused wafer scaffolds, and grown for 10 days in a rotational oxygen-permeable bioreactor system. (mendeley.com)
- The purpose of this research was to describe the prevalence of alveolar bone loss according to smoking status in Norway. (arctichealth.org)
- Morphometric registration of alveolar bone loss was carried out after 30 days of ligature placement to determine the effect of obesity on the progression of experimental peiodontitis. (ufrgs.br)
- Morphometric analysis was used to evaluate alveolar bone loss. (biomedcentral.com)
- Its anatomy is important for evaluating the morphometric symmetry of the mental triangle, microscopic and macroscopic morphology and maturity of the human mandible, bone remodeling activity and paleoanthropologic features of the facial skeleton in different populations. (ispub.com)
- Immune responses to infection trigger loss of alveolar bone from the jaw and eventual tooth loss. (hindawi.com)
- Therefore, the current investigation introduced a new mouse model of periodontal disease to examine the effects of a polymicrobial infection on periodontal ligament (PDL) properties, changes in bone loss, the host immune response, and the microbiome/virome using shotgun sequencing. (nature.com)
- Associations were found between bone loss, specific viral and bacterial species, immune genes, and PDL space changes. (nature.com)
- Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar bone on the 2 molars between which the injections were made, and by measuring the ratio of root area/enamel area in the same region. (nebraska.edu)
- The cemento- enamel junction ( CEJ ) was stained with 1% methylene blue and the alveolar bone loss in the buccal/palatal surfaces was measured linearly in 5 points on standardized digital photographs. (bvsalud.org)
- A comparison between enamel matrix proteins used alone or in combination with bovine porous bone mineral in the treatment of intrabony periodontal defects in humans. (biomedsearch.com)
- Intrabony defects were treated either with enamel matrix proteins (EMP group) or with enamel matrix proteins combined with bovine porous bone mineral (EMP/BPBM group). (biomedsearch.com)
- Histological and immunohistochemical analyses of the excised hybrid tooth-bone constructs revealed the presence of tooth tissues, including primary and reparative dentin and enamel in the tooth portion of hybrid tooth-bone implants, and osteocalcin and bone sialoprotein-positive bone in the bone portion of hybrid tooth-bone constructs. (mendeley.com)
- Eventually, this progression can cause tooth loss and systemic disease. (veterinarypartner.com)
- The articles included in the analysis were published in the English language and reported data on the use of implants with lengths below 10 mm in the posterior region with reduced alveolar bone height making the placement of longer implants impossible without additional surgical interventions. (medscimonit.com)
- Evaluate the effects of estrogen on alveolar bone loss rates in these patients. (clinicaltrials.gov)
- The aim of this study is to evaluate the bone dimension changes followed autotransplantation treatment. (clinicaltrials.gov)
- The purpose of this study was to evaluate the use of short dental implants in distally reduced alveolar bone height. (medscimonit.com)
- Monje A, Insua A, Monje F, Muñoz F, Salvi GE, Buser D, Chappuis V. Diagnostic accuracy of the implant stability quotient in monitoring progressive peri-implant bone loss: An experimental study in dogs. (harvard.edu)
- In this study, researchers first determined whether mice that were induced with experimental arthritis also manifested bone loss in the alveolar (tooth socket) bone. (elsevier.com)
- It was found that MT01, one of the ODNs with the sequences of human mitochondrial DNA, stimulated the proliferation of BMSCs, the differentiation of BMSCs to osteoblasts and mRNA expression of bone-associated factors including Runx2, Osterix, OPG, RANKL and collagen I in vitro . (mdpi.com)
- A positive correlation was found between alveolar bone loss in buccal/palatal and proximal surfaces. (bvsalud.org)
- Areas with and without ligature -induced periodontal destruction allow detection of alveolar bone loss in buccal/palatal and proximal surfaces. (bvsalud.org)
- The biological plausibility has been well documented, and the best evidence suggests the potential influence of diabetes on periodontal disease is likely explained by 1 ) a hyperinflammatory response to infection, 2 ) uncoupling of bone destruction and repair, and/or 3 ) the effects of advanced glycation end products ( 10 , 11 ). (diabetesjournals.org)
- Although bacterially-mediated mechanisms of alveolar bone destruction have been widely studied, the effects of a polymicrobial infection on the periodontal ligament and microbiome/virome have not been well explored. (nature.com)
- Changes in the PDL space were present at sites far away from the site of insult, indicating that the polymicrobial radius of effect extends beyond the bone loss areas and site of initial infection and wider than previously appreciated. (nature.com)
- Using mice deficient in NCR1 (the mouse orthlogue of NKp46), we demonstrate that oral infection of mice with F. nucleatum , but not with P. gingivalis results in an NCR1-dependent alveolar bone loss. (pubmedcentralcanada.ca)
- Untreated, it often leads to tooth loss and alveolar bone loss. (amfs.com)
- Investigators used a measure called alveolar crestal height to determine the amount of oral bone loss. (bio-medicine.org)
- Annual alveolar bone loss in older adults taking oral bisphosphonate: a retrospective cohort study. (harvard.edu)
- Participants in the placebo group may be removed from study if bone loss exceeds 5% per year. (clinicaltrials.gov)
- Regression analyses were performed to study the relationship between smoking duration and alveolar bone loss. (arctichealth.org)
- To test this hypothesis, the relationship between smoking duration and alveolar bone loss should be studied in a prospective study design. (arctichealth.org)
- In this study, 42 patients with Astra implants in sinuses that had been augmented with alloplasts and allografts or xenografts (alveolar bone height ≤ 5 mm) were selected. (ovid.com)
- The Toronto Study: Bone Level Changes. (ebscohost.com)
- It is considered a highly suitable model to study bone remodeling activity and the maturity pattern of the human mandible.Its modal position varies according to age and race and has been cited ranging from sub canine to sub molar in different populations. (ispub.com)
- In this pilot study the research protocol for an in vivo experiment with a new calcium phosphate bone augmenting ceramic material, was evaluated. (uppsatser.se)
- Apart from the pilot study, the master thesis includes a literature review of dental implants, bone augmenting materials and how the rabbit can be used as an animal model in dental implant research. (uppsatser.se)
- Alveolar bone loss using salivary and serum-derived bone markers. (clinicaltrials.gov)
- Salivary ALP levels may be useful as a potential bone turnover marker to establish the diagnosis and prognosis of periodontal disease. (ispub.com)
- Effects of Curcumin on Alveolar Bone Los. (cumhuriyet.edu.tr)