Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.
The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth.
Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
The constricted part of the tooth at the junction of the crown and root or roots. It is often referred to as the cementoenamel junction (CEJ), the line at which the cementum covering the root of a tooth and the enamel of the tooth meet. (Jablonski, Dictionary of Dentistry, 1992, p530, p433)
Infections with bacteria of the family BACTEROIDACEAE.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Bone loss due to osteoclastic activity.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).
The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.
Technique involving the passage of X-rays through oral structures to create a film record while a central tab or wing of dental X-ray film is being held between upper and lower teeth.
Photographic techniques used in ORTHODONTICS; DENTAL ESTHETICS; and patient education.
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
A hollow part of the alveolar process of the MAXILLA or MANDIBLE where each tooth fits and is attached via the periodontal ligament.
Infections with bacteria of the genus ACTINOBACILLUS.
A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.
An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.
Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.
One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.
Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.
Conservative contouring of the alveolar process, in preparation for immediate or future denture construction. (Dorland, 28th ed)
Oral tissue surrounding and attached to TEETH.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.
Application of a ligature to tie a vessel or strangulate a part.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.
Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.
Orthodontic techniques used to correct the malposition of a single tooth.
Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
The emergence of a tooth from within its follicle in the ALVEOLAR PROCESS of the MAXILLA or MANDIBLE into the ORAL CAVITY. (Boucher's Clinical Dental Terminology, 4th ed)
The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821)
A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.
The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992)
The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.
X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.
Extracellular substance of bone tissue consisting of COLLAGEN fibers, ground substance, and inorganic crystalline minerals and salts.
The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
Surgical procedure to add bone to the ALVEOLAR RIDGE in children born with a CLEFT LIP and a CLEFT PALATE.
The process of bone formation. Histogenesis of bone including ossification.
The grafting of bone from a donor site to a recipient site.
Diseases of BONES.
Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.
Tumors or cancer located in bone tissue or specific BONES.
One of a set of bone-like structures in the mouth used for biting and chewing.
The surgical removal of a tooth. (Dorland, 28th ed)
Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.
Radiographic techniques used in dentistry.
The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)
Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.
Horizontal and, to a lesser degree, axial movement of a tooth in response to normal forces, as in occlusion. It refers also to the movability of a tooth resulting from loss of all or a portion of its attachment and supportive apparatus, as seen in periodontitis, occlusal trauma, and periodontosis. (From Jablonski, Dictionary of Dentistry, 1992, p507 & Boucher's Clinical Dental Terminology, 4th ed, p313)
Elements of limited time intervals, contributing to particular results or situations.
Biocompatible materials placed into (endosseous) or onto (subperiosteal) the jawbone to support a crown, bridge, or artificial tooth, or to stabilize a diseased tooth.
A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.
The longest and largest bone of the skeleton, it is situated between the hip and the knee.

Morphological changes in periodontal mechanoreceptors of mouse maxillary incisors after the experimental induction of anterior crossbite: a light and electron microscopic observation using immunohistochemistry for PGP 9.5. (1/419)

Ruffini nerve endings (mechanoreceptors) in the periodontal ligament (PDL) of mouse incisors were examined to elucidate whether experimentally-induced crossbites cause any changes or abnormalities in their morphology and distribution. Anterior guiding planes were attached to the mandibular incisors of 3-week-old C3H/HeSlc mice. At 3 days and 1, 2, 4, 6, and 8 weeks post-attachment of the appliance, the mice were sacrificed by perfusion fixation. Frozen sagittal cryostat sections of the decalcified maxillary incisors were processed for immunohistochemistry of protein gene product 9.5, followed by histochemical determination of tartrate-resistant acid phosphatase activity to reveal sites of alveolar bone resorption. Despite the absence of bone resorption within the lingual PDL of control mice, distinct resorption sites were seen in the respective regions of the experimental animals. Unlike the controls, many Ruffini endings showing vague and swollen contours, with unusually long and pedunculated micro-projections were observed in the affected lingual PDL of the incisors in the experimental animals with short-term anterior crossbite induction. Club-shaped nerve terminations with few, if any, micro-projections were observed in the lingual PDL of experimental animals with long-term induction, as well as in aged control mouse incisors. Differences in the distribution of Ruffini endings were also observed. These results indicate that changing the direction of the force applied to the PDL results in rapid and prolonged changes in the morphology of Ruffini-like mechanoreceptors.  (+info)

Histological and histochemical quantification of root resorption incident to the application of intrusive force to rat molars. (2/419)

This study was conducted to investigate the nature of root resorption resulting from intrusive forces applied to the rat lower molars, by means of histological and histochemical techniques with tartrate resistant acid phosphatase (TRAP). Thirty-eight 13-week-old Wistar strain male rats were used. Intrusive force was created by a fixed appliance which was adjusted to exert an initial force of 50 g for the duration of 1, 2, and 3 weeks. The degree of root resorption and distribution of TRAP positive cells were evaluated. On the root surface, the TRAP positive scores were low in the apical regions. Significant differences in the scores were found in the inter-radicular region of the roots between the experimental and control groups for the 2- and 3-week groups. More active resorption of bone occurred during the experimental period, as denoted by greater TRAP positive scores on the bone than on the root surface. Root resorption scores in the apical root region were larger in the 2- and 3-week groups than in the 1-week group. Significant differences in the root resorption scores were also found between the 1- and 3-week groups in the inter-radicular region, indicating that intrusive force application of a longer duration may lead to a higher frequency of root resorption. It is shown that, irrespective of the level of TRAP positive cells and root resorption scores, the degree of root resorption activity is higher in the apical root region than in the inter-radicular area. These results indicate that cellular cementum may be resorbed more easily because of its richer organic components and low mineralized structure.  (+info)

Host modulation as a therapeutic strategy in the treatment of periodontal disease. (3/419)

Specific microorganisms initiate the immunoinflammatory processes that destroy tissue in periodontitis. Recent work has demonstrated, in addition to bacterial control, that modulation of the host immunoinflammatory response is also capable of controlling periodontitis. Matrix metalloproteinases (MMPs) destroy collagen and other matrix components, and the osteoclastic bone remodeling determines the periodontal bone response to a bacterial challenge. Other components of the biology, including cytokines and prostanoids, regulate MMPs and bone remodeling and are also involved in regulating the production of defensive elements, such as antibody. Agents directed at blocking MMPs or osteoclastic activity are effective in reducing periodontitis. Agents that inhibit prostaglandin E2 and selective blockage of specific cytokines have also been effective. Improved knowledge of bacterium-host interactions and of the processes leading to tissue destruction will help to identify targets for host modulation to reduce periodontitis in selected situations.  (+info)

CD4(+) T cells and the proinflammatory cytokines gamma interferon and interleukin-6 contribute to alveolar bone loss in mice. (4/419)

In this study, we used a mouse model to examine the role of the adaptive immune response in alveolar bone loss induced by oral infection with the human gram-negative anaerobic bacterium Porphyromonas gingivalis. Severe combined immunodeficient mice, which lack B and T lymphocytes, exhibited considerably less bone loss than did immunocompetent mice after oral infection, suggesting that lymphocytes contribute to this process. Bone loss after oral infection was decreased in mice deficient in major histocompatibility complex (MHC) class II-responsive CD4(+) T cells, but no change in bone loss was observed in mice deficient in MHC class I-responsive CD8(+) T cells or NK1(+) T cells. Mice lacking the cytokine gamma interferon or interleukin-6 also demonstrated decreased bone loss. These results suggest that the adaptive immune response, and in particular CD4(+) T cells and the proinflammatory cytokines that they secrete, are important effectors of bone loss consequent to P. gingivalis oral infection. The studies also reinforce the utility of the mouse oral infection model in dissecting the pathobiology of periodontal disease.  (+info)

C-telopeptide pyridinoline cross-links. Sensitive indicators of periodontal tissue destruction. (5/419)

C-telopeptides and related pyridinoline cross-links of bone Type I collagen are sensitive markers of bone resorption in osteolytic diseases such as osteoporosis and osteoarthritis. We have studied the release of C-telopeptide pyridinoline crosslinks of Type I collagen as measures of bone destruction in periodontal disease. Studies in preclinical animal models and humans have demonstrated the relationship between radiographic bone loss and crevicular fluid C-telopeptide levels. We have recently found that C-telopeptide levels correlate strongly with microbial pathogens associated with periodontitis and around endosseous dental implants. Host-modulation of bone-related collagen breakdown has been shown by studies in humans demonstrating that MMP inhibition blocks tissue destruction and release of C-telopeptides in patients with active periodontal disease.  (+info)

Host responses to recombinant hemagglutinin B of Porphyromonas gingivalis in an experimental rat model. (6/419)

Porphyromonas gingivalis, a gram-negative, black-pigmented anaerobe, is among the microorganisms implicated in the etiology of adult periodontal disease. This bacterium possesses a number of factors, including hemagglutinins, of potential importance in virulence. Several hemagglutinin genes have been identified, cloned, and expressed in Escherichia coli. The purpose of this study was to characterize host responses to purified recombinant hemagglutinin B (rHag B), using the conventional Fischer rat as the experimental animal model. The effectiveness of immunization with rHag B on protection against experimental periodontal bone loss following infection with P. gingivalis was also evaluated. Groups of rats were immunized by the subcutaneous route with rHag B in complete Freund's adjuvant, immunized with rHag B and orally infected with P. gingivalis, nonimmunized and noninfected, or orally infected with P. gingivalis only. Serum and saliva samples were collected throughout the experiment and evaluated for serum immunoglobulin G (IgG) and IgM and salivary IgA antibody activity by enzyme-linked immunosorbent assay. No salivary IgA anti-Hag B activity was detected in the various groups of rats. A slight serum IgM response similar to that seen in preimmune samples was observed. Serum IgG antibody activity to Hag B was detected only in samples from rats immunized with rHag B. This response was primarily of the IgG1 and IgG2a subclasses, followed by IgG2b and low levels of IgG2c. Supernatants from rHag B-stimulated splenic lymphoid cell cultures from immunized rats contained high levels of gamma interferon, followed by interleukin-2 (IL-2), IL-10, and then IL-4. These results are consistent with the induction of T helper type 1 (Th1)- and Th2-like responses. Western blot analysis of sera derived from rHag B-immunized rats reacted with trichloroacetic acid (TCA) precipitates of P. gingivalis 33277, 381, A7A1-28, and W50, revealing a 50-kDa band reflective of Hag B. However, sera derived from rats immunized with P. gingivalis whole cells or from rats infected with P. gingivalis only did not react with rHag B but did react with TCA precipitates of P. gingivalis strains. Finally, radiographic measurements of periodontal bone loss indicated that rats immunized with rHag B had less bone loss than those infected with P. gingivalis only. These results demonstrate the effectiveness of purified rHag B in inducing a protective immune response and support the potential usefulness of this component of P. gingivalis in the development of a vaccine against adult periodontitis.  (+info)

Requirement of B7 costimulation for Th1-mediated inflammatory bone resorption in experimental periodontal disease. (7/419)

The CD28 costimulation at TCR signaling plays a pivotal role in the regulation of the T cell response. To elucidate the role of T cells in periodontal disease, a system of cell transfer with TCR/CD28-dependent Th1 or Th2 clones was developed in rats. Gingival injection of specific Ag, Actinobacillus actinomycetemcomitans 29-kDa outer membrane protein, and LPS could induce local bone resorption 10 days after the transfer of Ag-specific Th1 clone cells, but not after transfer of Th2 clone cells. Interestingly, the presence of LPS was required not only for the induction of bone resorption but also for Ag-specific IgG2a production. LPS injection elicited the induction of expression of both B7-1 and B7-2 expression on gingival macrophages, which otherwise expressed only MHC class II when animals were injected with Ag alone. The expression of B7 molecules was observed for up to 3 days, which corresponded to the duration of retention of T clone cells in gingival tissues. Either local or systemic administration of CTLA4Ig, a functional antagonist of CD28 binding to B7, could abrogate the bone resorption induced by Th1 clone cells combined with gingival challenge with both Ag and LPS. These results suggest that local Ag-specific activation of Th1-type T cells by B7 costimulation appeared to trigger inflammatory bone resorption, whereas inhibition of B7 expression by CTLA4Ig might be a therapeutic approach for intervention with inflammatory bone resorption.  (+info)

Long-term follow-up of maxillary incisors with severe apical root resorption. (8/419)

The purpose of the study was to analyse the mobility of teeth with severe orthodontically induced root resorption, at follow-up several years after active treatment, and to evaluate mobility in relation to root length and alveolar bone support. Seventy-three maxillary incisors were examined in 20 patients, 10-15 years after active treatment in 13 patients (age 24-32 years) and 5-10 years after active treatment in seven patients (age 20-25 years). All had worn fixed or removable retainers; seven still had bonded twistflex retainers. Total root length and intra-alveolar root length were measured on intra-oral radiographs. Tooth mobility was assessed clinically according to Miller's Index (0-4) and the Periotest method. Crestal alveolar bone level, periodontal pocket depth, gingival, and plaque indices, occlusal contacts during occlusion and function, and dental wear were recorded. There was a significant correlation (P < 0.05) between tooth mobility, and total root length and intra-alveolar root length. No correlation was found between tooth mobility and retention with twistflex retainers. None of the variables for assessment of periodontal status, occlusion and function were related to total root length or tooth mobility. It is concluded that there is a risk of tooth mobility in a maxillary incisor that undergoes severe root resorption during orthodontic treatment, if the remaining total root length is < or = 9 mm. The risk is less if the remaining root length is > 9 mm. Follow-up of teeth with severe orthodontically induced root resorption is indicated.  (+info)

TY - JOUR. T1 - Effect of an aldose reductase inhibitor on alveolar bone loss associated with periodontitis in diabetic rats. AU - Kador, Peter F.. AU - Hamada, Tomofumi. AU - Reinhardt, Richard A.. AU - Blessing, Karen. PY - 2010/5/1. Y1 - 2010/5/1. N2 - Periodontitis is a lesser known but frequent complication of diabetes mellitus and is the major cause of tooth loss in patients with diabetes. Dental therapy for this complication is primarily focused on the control of oral infections. No current therapy directly addresses the potential effects of diabetes itself on this complication. In studies conducted in young normal control and streptozotocin diabetic rats (100 g) treated with and without the aldose reductase inhibitor (ARI) imirestat, experimental periodontitis was induced in one side of the mouth by 3 injections of lipopolysaccharide (LPS) from Escherichia coli 055:B5 9 into the palatal gingiva between the first and second maxillary molars at 48-hour intervals. The other control side was ...
BACKGROUND AND OBJECTIVES: Strontium ranelate is a medication indicated for the treatment of osteoporosis that presents concomitant anti-resorptive and osteoanabolic dual biological activity. However, the effects of strontium ranelate on alveolar bone have been poorly explored. Furthermore, to date, there are no data on the effects of this medication on alveolar bone loss (BL) during conditions of estrogen deficiency. Therefore, the aim of this study was to evaluate the effects of strontium ranelate on ligature-induced periodontitis in estrogen-deficient and estrogen-sufficient rats. METHODS: Ninety-six rats were assigned to one of the following groups: sham-surgery + water (estrogen-sufficient; n = 24); ovariectomy + water (estrogen-deficient; n = 24), sham-surgery + strontium ranelate (ranelate/estrogen-sufficient; n = 24) and; ovariectomy + strontium ranelate (ranelate/estrogen-deficient; n = 24). The rats received strontium ranelate or water from the 14th day after ovariectomy until the end ...
Objective: In this study we have assessed the renal and cardiac consequences of ligature-induced periodontitis in both normotensive and nitric oxide (NO)-deficient (L-NAME-treated) hypertensive rats.Materials and methods: Oral L-NAME (or water) treatment was started two weeks prior to induction of periodontitis. Rats were sacrificed 3, 7 or 14 days after ligature placement, and alveolar bone loss was evaluated radiographically. Thiobarbituric reactive species (TBARS; a lipid peroxidation index), protein nitrotyrosine (NT; a marker of protein nitration) and myeloperoxidase activity (MPO; a neutrophil marker) were determined in the heart and kidney.Results: In NO-deficient hypertensive rats, periodontitis-induced alveolar bone loss was significantly diminished. In addition, periodontitis-induced cardiac NT elevation was completely prevented by L-NAME treatment. on the other hand L-NAME treatment enhanced MPO production in both heart and kidneys of rats with periodontitis. No changes due to ...
DR could be a supplementary medicine for periodontal therapy as it could reduce bone resorption in rat model of alveolar bone resorption and exert osteogenic effect on osteoblasts.
Journal of Shahid Sadoughi University of Medical Sciences ماهنامه علمی پژوهشی دانشگاه علوم پزشکی و خدمات بهداشتی درمانی شهید صدوقی یزد
This might be one of several explanations as to why elevated bacteria and the combination of specific pathogens in periodontal pockets can be linked to a history of ACS, said Stefan Renvert, DDS, PhD and Department of Health Sciences, Kristianstad University. We also found that the amount of periodontal bacteria results in an inflammatory response that elevates the white blood cell counts and high sensitivity C-reactive protein levels, which has also been linked in past studies to heart disease.. It was also found that the extent of alveolar bone loss was significantly greater among subjects with ACS. Seventy-seven percent of the participants in the ACS group and 42 percent in the control group demonstrated evidence of periodontitis. The extent of bone loss was more severe in the ACS group than in the non-ACS group.. Another reason people diagnosed with ACS may have higher oral bacteria could be due to their infectious susceptibility and lack of an adequate host inflammatory response, which ...
Teens involvement in numerous sports and recreational activities will damage maxillofacial features. Cases like a broken tooth increase the feasibilities of root infections & provide an obnoxious smile. A lot of them also get obstacles in eating & speaking during overbite. The lifestyle choices of teens also influence the challenges of cavities, impacted wisdom teeth, crowding issues, and gum diseases. The hectic schedule of adults demands a restricted brushing routine, not sufficient to remove plaques. Decays develop as a result of this and eventually result in severe conditions like oral cancer or gum infections. They also experience excessive edentulism imposed by smoking & lack of oral hygiene. Such voids spaces left by missing teeth leads to excessive alveolar bone loss in addition to deterioration in facial aesthetics ...
Curcumin is a yellowish polyphenol extracted from the rizome of a herbaceous tropical plant. It has multiple biological activities described, including anti-inflammatory, antioxidant, antiangiogenic, immunomodulatory, cytotoxic, antimicrobial and pro- and antiapoptotic activities. Its therapeutic application is actively evaluated in preclinical models and clinical studies of various diseases. In vivo use of curcumin is limited by its pharmacodynamic propereties, such as poor solubility in aqueous vehicles, low absorption rate in the gastrointestinal tract and short half-life in the peripheral circulation. The aim of this study was to evaluate the dose-response effect of a synthetic compound that is structurally to natural curcumin (CMC2.24) in a model of experimental periodontal disease that mimics the host-microbial interaction and the resultant inflammation and bone resorption that are hallmarks of this conditions in humans. Periodontal disease was induced in mice by injection of 30 ug LPS of ...
OBJECTIVE: The purpose of this study was to evaluate whether local administration of TIL could influence the expression of the inflammatory mediators IL-1β, TNF-α, MMP-8 and COX-2 in rats with experimental periodontitis (EP). METHODS: Twenty-four adult male rats (Rattus norvegicus, albinus, Wistar) were assigned to groups C, EP, EP-TIL (CControl group, EP-Periodontitis groups). On EP groups, a ligature was placed around maxillary 2nd molars on day 1. On group EP-TIL, 20 μL of TIL solution (1 mg/kg body weight) was injected into the subperiosteal palatal area adjacent to the maxillary 2nd molar every other day until euthanasia (day 11 ...
Study Alveolar Bone flashcards from Faith Villaceran's University of the East class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.
(2005) Young et al. Tissue Engineering. Tooth loss accompanied by alveolar bone resorption presents a significant clinical problem. We have investigated the utility of a tissue-engineering approach to provide corrective therapies for too...
Particularly suited for treatment of smaller defects and periodontal bone defects. Can be cut to shape and size in dry or wet conditions. Does not stick to itself and to instruments. Can be easily repositioned, if needed. Exceptional adaptability to surface contour after rehydration.. ...
Vitamins and minerals essential for improving the nutritional environment of periodontal bone and tissue.These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
PROTOCOL OUTLINE: This is a randomized, double-blind, placebo controlled study. Patients are randomly assigned to receive placebo or conjugated estrogens and, if no prior hysterectomy, medroxyprogesterone. Patients also receive calcium supplementation therapy daily for 3 years.. Participants in the placebo group may be removed from study if bone loss exceeds 5% per year.. A study duration of 3 years is anticipated. ...
Purpose: The aim of this study was to compare vertical and horizontal mandibular alveolar bone resorption by measuring bone morphological variation in Kennedy Class II removable partial denture (RPD) wearers and non-wearers using cone-beam computed tomography (CBCT).. Materials and Methods: In total, 124 sites in the CBCT scans of 62 (29 RPD non-wearers, 33 RPD wearers) Kennedy Class II patients were analyzed retrospectively. Three-dimensional representations of the mandible with superimposed cross-sectional slices were developed with the CBCT scans to evaluate the mandibular alveolar height and width by measuring distances between the mandibular canal, mylohyoid ridge, alveolar crest, and lower border of the mandible in four regions (eight sites) of Kennedy Class II non-wearers and wearers of RPDs.. Results: Mandibular alveolar bone height and width were significantly lower in edentulous sites when compared with dentate sites in both Kennedy Class II non-wearers and wearers of RPDs (p , 0.05). ...
Oral bone loss is a major concern amongst a large population suffering from estrogen deficiency, osteoporosis and periodontal diseases. The clinical implication of oral bone loss is premature tooth loss. Mechanical loading has proven to be vital in maintaining the quantity and quality of the bone, particularly in impacted bone. Studies have shown that long bones (post-cranial) and alveolar bone (cranial) are both sensitive to mechanical environment through static and dynamic loading. It also has been suggested that whole body vibrations (WBV) at low-magnitude and high frequency are a non-invasive and non-pharmacological method to prevent bone loss, particularly in the long bones. However, not much has been said about the application of these low-magnitude high frequency loads on the alveolar bone. In this pilot study, it is determined if low magnitude of 0.3 g (where g = 9.8ms,super,-2,/super,) and high frequency of 50 Hz, localized vibrations can be transmitted to the alveolar bone and also ...
This study was planned to determine whether a short period dexamethasone treatment induce alveolar bone loss or not, therefore, twenty six male albino rabbits were divided into three groups as follow: Test groups I (10 rabbits) received 1.56 mg/kg dexamethasone intraperitoneal injection daily for two weeks, test group II (10 rabbits) received 3.12 mg/kg dexamethasone intraperitoneal injection daily, and the control group (6 rabbits) received saline solution for same period. The animals were sacrificed and histological sections were prepared from the alveolar bone of molar areas of mandible, as well as morphometric analysis of osteoclasts number was performed. The results showed a significant increase in the number of osteoclasts, which indicates that bone loss, is quite inevitable secondary to dexamethasone treatment even in a short period of treatment for two weeks.
In an article titled Periodontal Assessments of Postmenopausal Women Receiving Risedronate, a graduate of the Case Western Reserve University School of Dental Medicine, reports that drugs that are used to combat
Researchers at the University at Buffalo have been able to identify two key components in saliva that could be used to predict the amount of oral bone loss in future.
The treatment of intrabony defects is a real challenge in molar teeth as it is chronic, slowly progressing disease which needs timely intervention. Periodontal inflammation associated with intrabony defect is not a separate entity as it secondarily affects the pulp causing retrograde pulpitis. However, treatment of these lesions will be complicated due to extensive bone loss. The tooth was endodontically treated followed by periodontal surgery to eliminate the deep periodontal pocket and promote bone fill in osseous defect. PepGen P-15 composited with platelet rich plasma was utilized for enhancing bone formation. The combination of these graft materials provides synergistic effect on bone regeneration.
Researchers compared the effect of a daily atorvastatin 80 mg dose versus a 10 mg dose in a randomized, multi-center trial with 71 subjects with established atherosclerosis or risk factors for atherosclerosis. Patients were evaluated using F-Flurodexoyglucose positron emission tomography (FDG-PET) imaging. After 12 weeks, there was a significant reduction in periodontal inflammation in subjects randomized to the 80 mg dose (p=0.04). Reductions in periodontal inflammation were greatest in individuals with higher levels of periodontal inflammation at baseline (p=0.01) and in those with higher periodontal bone loss at baseline (p=0.03). The reductions in periodontal inflammation correlated with reductions in carotid inflammation (p,0.001). The impact of high-dose statin was greatest in individuals with evidence of active periodontitis and was evident after a four-week treatment period, said lead author Sharath Subramanian, MD, Massachusetts General Hospital and Harvard Medical School, Boston. We ...
Differing theories of the nature of periodontal disease progression have been proposed, but there is no convincing statistical evidence with which to choose between them. Three models for disease progression are developed, and their covariance structures are derived and shown to be hierarchical. The estimation of the covariance structures of...
Purpose: The purpose of this scholarly study is to evalute the anti-inflammatory ramifications of morus migra on experimentally-induced periodontitis in rats. Outcomes: Morus nigra treatment reduced tissues MMP-8 and MMP-13 amounts and there have been significant differences regarding tissue degrees of MMP-8 and MMP-13 between groupings PER and MN+PER (p=0.035, p=0.041). There have been no significant distinctions among all of the groupings serum degrees of MMP-8 and MMP-13 (p=0.067, p=0.082). In the histometric evaluation, alveolar bone loss was higher in the PER group compared to C and MN organizations (p=0.035). Immuno-histochemical staining of RANKL activities were found significantly lower (p=0.037) and OPG activities were found significantly higher in MN+PER group when compared to PER group (p=0.021). Summary: The present study shows that systemic administration of Morus nigra significantly inhibited the regional alveolar bone AC220 manufacturer resorption and contributes to periodontal ...
Results: No significant differences were found between both groups in survival, complications, or marginal bone resorption. One axially placed implant was lost at 58 months in group 1, rendering a cumulative survival estimate at 5 years of 96.7% and 98.3% in group 1 and the total sample, respectively (P = .317). Mechanical complications occurred in 16 patients (26.7%; n = 8 patients in each group; [P > .999]), consisting of fractures in the provisional prosthesis (n = 8 patients), chipped ceramics of the definitive prosthesis (n = 2 patients), loosening of prosthetic components (n = 5 patients), and fracture of an attachment screw (n = 1 patient). Biologic complications occurred in 5 patients (8.3%; group 1 = 4 patients; group 2 = 1 patient; [P = .161]), consisting of peri-implant pathology. The mean ± SD marginal bone loss was 2.02 ± 0.36 mm and 1.90 ± 0.69 mm for groups 1 and 2, respectively (P = .235). In group 1, the mean ± SD marginal bone loss was 1.92 ± 0.48 mm and 2.11 ± 0.44 mm ...
Parathyroid hormone is an endogenous hormone with potent anabolic and catabolic actions in bone. It has recently been approved for the treatment of osteoporosis and is marketed as FORTEO by Eli Lilly and Company. Numerous studies in humans have validated its use to increase bone mineral density and prevent fractures. Interest has also surfaced in its potential application in the treatment of non-osteoporotic fractures and several animal studies have supported this local application. Little is known regarding its use in treating conditions of the oral cavity, but animal studies suggest that bones of the oral cavity are responsive to the anabolic actions of PTH. Furthermore, a recent study indicated that in a canine model, PTH was effective at reversing periodontal bone loss. Studies from our laboratory indicate that patients with hyperparathyroidism (HPT) do not have an increase in periodontal disease as measured by attachment levels. In fact, in our patient population there was an increase in ...
The main finding is that the enhanced alveolar bone loss associated to age may be targeted by an appropriate dietary treatment. Our method uses biological knowledge expressed by Gene Ontology and generates a rule model associating this knowledge with minimal characteristic features of temporal gene expression profiles. The relatively low attack rate and also relative risk requires large sample sizes for free cialis generic testing hypotheses. From genes to function: the next challenge to understanding multiple sclerosis.. Recommendations for early diagnosis and intervention in autism spectrum disorders: an Italian-Israeli consensus conference. The purpose of this article is to reexamine some of the principles of correction. 6-Shogaol was shown to damage microtubules and discount generic cialis induce mitotic arrest. There was a weak association between adduct levels and daily cigarette consumption above 10 cigarettes per day. The results indicate that the PFD could be a useful tool for ...
The Straumann® Bone Level Tapered (BLT) Implant offers all the clinically proven features of the Straumann® Bone Level Implant line plus the advantages of a tapered implant body. This leads to excellent primary stability in soft bone and fresh extraction sockets. The tapered form adequately compresses the underprepared osteotomy. It also lets you effectively master your patients limited anatomy, such as facial undercuts, converging root tips, a concave jaw structure or narrow atrophied ridges ...
Australian Wine Cluster Supplementary Information Case Study Help, Case Study Solution & Analysis & Obesity induces gingival oxidative pressure, thats associated with the development of alveolar bone resorption. The antioxidant influence of hydrogen-load
Current therapeutics such as bisphosphonates or anabolic agents do not always effectively prevent or treat osteoporosis and inflammatory bone loss in rheumatoid...
I am new to the forum and tomorrow I am going in for the beginning of having dental implants due to bone loss! I have been so confused as to why I have had bone loss. I had PE with all 3 of my children and HELLP with my second. My youngest is 8 years old and I am approaching 49. My Mother had PE her first pregnancy and had dental bone loss issues. Back in the 1970s they told her here bone loss was due to her pregnancies. I am glad I decided to search for this. It gives me something to think about ...
31 years-old male patient was loss of anterior teeth for 1 year. . We have treated this case using Geistlich Bio-Oss® and Geistlich Bio-Gide® guide bone regeneration. After 6 months, the post-examination showed that that site had well-developed alveolar bone. After 1 year, permanent restoration was performed.. ...
Periodontal Fiber Definition Periodontal fiber is attached to the dentin of the root of the tooth by cementum and to the bone of the jaws by alveolar bone.
Bone loss is a problem that not only plagues the elderly, but the younger generation as well. This condition does not form overnight. Nobody can say that with just a ...
Implant dentistry in the esthetic zone is highly challenging. In recent years there are several studies, well defined approaches available on how to achieve pleasing outcomes. We must understand the biology of extraction sites and different treatment options for preserving or even reconstructing bony structures for predictable implant placement. This clinical and evidence based presentation will emphasize the importance of proper 3-dimensional implant placement, show different bone preservation techniques i.e P.E.T. (Partial Extraction Therapy) and how soft tissue grafting can effect the final end result. However we must admit that not only surgery but prosthetic skills have a major influence on our work. Implant placement must be determined with the prosthetic plan in mind! On the other hand abutment design, platform shifting concept as tissue molding tools and screw retained solutions will be high-lighted with lots of case presentations.. ...
TY - JOUR. T1 - Incisive canal cysts related to periodontal osseous defects. T2 - case reports.. AU - Mealey, B. L.. AU - Rasch, M. S.. AU - Braun, J. C.. AU - Fowler, C. B.. PY - 1993/6. Y1 - 1993/6. N2 - The incisive canal cyst is the most common non-odontogenic cyst of the oral cavity. While the cyst has frequently been described, the relationship between the lesion and adjacent periodontal osseous defects has rarely been reported. This paper describes the occurrence and treatment of incisive canal cysts in two patients with severe adult periodontitis on maxillary incisor teeth.. AB - The incisive canal cyst is the most common non-odontogenic cyst of the oral cavity. While the cyst has frequently been described, the relationship between the lesion and adjacent periodontal osseous defects has rarely been reported. This paper describes the occurrence and treatment of incisive canal cysts in two patients with severe adult periodontitis on maxillary incisor teeth.. UR - ...
Atherosclerotic vascular disease is a leading cause of myocardial infarction and cerebrovascular accident, and independent associations with periodontal disease (PD) are reported. PD is caused by polymicrobial infections and aggressive immune responses. Genomic DNA of Porphyromonas gingivalis, the best-studied bacterial pathogen associated with severe PD, is detected within atherosclerotic plaque. We examined causal relationships between chronic P. gingivalis oral infection, PD, and atherosclerosis in hyperlipidemic ApoEnull mice. ApoEnull mice (n = 24) were orally infected with P. gingivalis for 12 and 24 weeks. PD was assessed by standard clinical measurements while the aorta was examined for atherosclerotic lesions and inflammatory markers by array. Systemic inflammatory markers serum amyloid A, nitric oxide, and oxidized low-density lipoprotein were analyzed. P. gingivalis infection elicited specific antibodies and alveolar bone loss. Fluorescent in situ hybridization detected viable P. gingivalis
Clinicians very often have seen marginal bone loss around dental implants at the crest level early on after implant placement and uncovering. Early clinical publications had suggested that this bone loss occurred during the first year of loading. Thus, numerous attempts have been made to minimize or eliminate such bone loss. However, the timing and reason for this bone loss are not always apparent. The objective of this study was to review the evidence regarding marginal bone loss around dental implants from the standpoint of biologic consequences to help understand marginal bone changes around dental implants. One hypothesis for the bone loss around these implants was related to the presence of bacteria in the interfaces between the implant and abutment connections. The literature was reviewed regarding the three major types of implant-abutment crestal connections, including butt-joint, platform-switched, and no interface (tissue-level or one-body). This review article revealed that 1.5 to 2.0 ...
TY - JOUR. T1 - Supplementation of broccoli or Bifidobacterium longum-fermented broccoli suppresses serum lipid peroxidation and osteoclast differentiation on alveolar bone surface in rats fed a high-cholesterol diet. AU - Tomofuji, Takaaki. AU - Ekuni, Daisuke. AU - Azuma, Tetsuji. AU - Irie, Koichiro. AU - Endo, Yasumasa. AU - Yamamoto, Tatsuo. AU - Ishikado, Atsushi. AU - Sato, Takehiko. AU - Harada, Kayo. AU - Suido, Hirohisa. AU - Morita, Manabu. N1 - Funding Information: This study was supported by Grants-in-Aid for Scientific Research ( 20791642 ) from the Ministry of Education, Culture, Sports, Science, and Technology, Tokyo, Japan . The authors have no conflicts of interest to declare.. PY - 2012/4. Y1 - 2012/4. N2 - High-cholesterol diet enhances osteoclastic activity on alveolar bone by increasing serum lipid peroxidation. We hypothesized that supplementation with dietary antioxidants, such as found in broccoli and its fermented products, might suppress increases in serum lipid ...
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A range of regenerative treatments have been used for the treatment of periodontal infrabony defects. Guided tissue regeneration (GTR) and enamel matrix derivatives (EMD) are two popular treatment and they have both been used in combination with other treatment. This network meta-analysis was conducted to assess the potential effects of the various combinations. Unlike a [read the full story…]. ...
The suitability of a mouse model for host response in the induction of alveolar bone loss by Porphyromonas gingivalis was explored. The mouths of immunocompetent and severe combined immunodeficient (SCID) mice were infected with P. gingivalis ATCC 53977. P. gingivalis was not isolated from the mouths of these mice before infection, but was present at least 42 days after infection. P. gingivalis-specific IgG was present in sera from the infected, immunocompetent mice at the end of these experiments (42 days). Specific IgG was not present in sham-infected or uninfected immunocompetent mice, nor in any immunodeficient mice. Specific IgM was not present in any sera at 42 days. Infected, immunocompetent mice of two strains showed significant bone loss in comparison to sham-infected or uninfected immunocompetent mice (p | 0.05). Infected SCID mice, which are genetically lacking both B and T lymphocytes, also showed significant bone loss compared with sham-infected or uninfected SCID mice (p | 0.05
PURPOSE: The purpose of this animal study was to confirm that laser Doppler flowmetry (LDF) is a reproducible method for the assessment of maxillary and mandibular alveolar bone vascularity and that there is less vascularity in irradiated mandibular and maxillary bone compared to nonirradiated bone. MATERIALS AND METHODS: All maxillary and mandibular premolars and molars of 6 Gottingen minipigs were extracted. After a 3-month healing period, 3 minipigs received irradiation at a total dose of 24 Gy. Three months after irradiation, 5 holes were drilled in the residual alveolar ridge of each edentulous site in each minipig. Local microvascular blood flow around all 120 holes was recorded by LDF prior to implant placement. In 1 irradiated and 1 nonirradiated minipig, an additional hole was drilled in a right maxillary site to enable repeated LDF recordings. RESULTS: The alveolar bone appeared less vascularized in irradiated than in nonirradiated minipigs. The effect of radiation appeared more ...
Incisor trauma is common in children, and can cause severe complications during adolescent growth and development. This report describes the treatment of a 16-year-old patient with severe anterior open bite due to ankylosis of the maxillary left incisor after dental trauma as an 8-year-old. No examination or active treatment was undertaken until he was 16 years old. Clinical examination revealed that the maxillary left incisor was severely intruded accompanied by a vertical alveolar bone defect. Orthodontic treatment combined with surgical luxation took 3 years and 7 months. During treatment, the intruded incisor was moved to the occlusal level and the alveolar bone defect was restored, achieving normal occlusion. After two years of retention, the maxillary left incisor was retained in a stable normal position with a slightly reduced overbite. This case demonstrates that surgical luxation with orthodontic traction can be an effective approach, especially when the ankylosed tooth has a single root. Long
Dietary fish oil has been shown to inhibit bone resorption and, therefore, the aim of the present study was to test the hypothesis that fish oil alters lipopolysaccharide (LPS)-induced hydroxyapatite loss in rat alveolar bone. Rats were divided into four groups. The animals injected with saline or Escherichia coli-derived LPS into the maxillary alveolar mucosa on the buccoapical site of the molar region daily for 8 days were served as a negative or positive control, respectively. Other groups of animals were injected with LPS and orally treated with fish oil at the same day with or after LPS injection. The results of the present study showed that the hydroxyapatite contents of alveolar bone in rats treated with fish oil at the same day with or before LPS injection were significantly higher than those in rats injected with LPS alone, but still lower than those in untreated animals. Therefore, the present study suggests that oral treatment with fish oil may reduce LPS-induced hydroxyapatite loss ...
Academic Dissertations;Academic Dissertations--South Carolina;Periodontal Ligament;Osteonectin;Cysteine;Collagen;Dental Cementum;Collagen Type I;Tooth Loss;Alveolar Bone Loss;Transglutaminases;Periodontium;Extracellular Matrix; ...
Non-healing bone fractures and periodontal bone loss constitute significant clinical problems with few approved medical options. Bone repair is enhanced by the presence of osteoblasts or osteoblastic precursor cells. Subcutaneous adipose tissue is a plentiful, accessible, and replenishable source of human stromal cells for transplantation. In Phase I of this SBIR, we tested the hypothesis that human adipose tissue-derived stromal cells are capable of osteoblast function. Substantial in vitro data indicates that these stromal cells differentiate into cells biochemically and morphologically similar to osteoblasts. The ability of these cells to form bone in vivo was examined as well. Phase II of this SBIR will extend these in vivo experiments. Specific Aim 1 examines the ability of human adipose tissue-derived stromal cells to form ectopic bone in hydroxyapatite ceramic cubes implanted subcutaneously in immunodeficient mice. Specific Aim 2 explores whether the introduction of a modified bone ...
If you have been in practice long enough, you will have run into something like this eventually. This is a 76 year old farmer who has fairly obviously been grinding his teeth. In fact, you would be making a correct assumption. Note that the tooth wear is much worse anteriorly than it is in the posterior. As we will eventually see, this is diagnostic of abrasion from bruxism. But notice a few other less obvious things. You see no occlusal amalgam fillings in the posterior teeth. You see no plaque or redness around the gingiva. You see no active decay anywhere. Furthermore, the patient has no periodontal bone loss in spite of a serious bruxing habit. On the other hand, you do see a few buccal composite fillings along with severe buccal-cervical wear. We can conclude the following from these observations:. This patient has probably never used too much sugar. We conclude this by the lack of amalgam fillings in the intact molars and the occlusal of #4, the one surviving premolar.. The patient has ...
Our understanding about periodontal disease progression improved tremendously during 1960s, when animal and human experiments demonstrated the role of bacteria in the initiation of gingivitis and periodontitis 1, 2. These studies led to the proposal of the model of bacterial etiology of periodontal disease. Further investigations in this field led to the advancement of our knowledge of pathogenic bacteria causing disease progression. Specific Gram-negative, anaerobic, or microaerophilic bacteria were implicated in the causation of periodontitis 3-7. During late 1970s and early 1980s protective and destructive roles of the immunoinflammatory responses were described in health and disease 8-14.. Most of the models of periodontal disease progression in the late 1980s stated that specific bacteria initiated the disease process by activating host responses, which were protective and destructive. The actual destruction of connective tissue and bone resulted primarily from inflammatory chemical ...
A polylactide-polyglicolide(PLA-PGL) has been documented clinically to enhance bone regeneration in closed bone defects and to sustain periodontal healing in intrabony defects. So far, there are no controlled clinical studies to compare the effect of the PLA-PGL with the effect of other biological agents in treating deep intrabony defects. Aim of the study: to compare treatment of deep intrabony defects with PLA-PGL(Fisiograft®,Ghimas,Italy) to an enamel-matrix-protein-derivative(EMD; Emdogain®,Straumann AG,Waldenburg,Switzerland). Nineteen patients, displaying 26 intrabony defects, were randomly treated with PLA-PGL (test) or with EMD(control). Soft tissue measurements were made at baseline and 6 months after. No differences in the investigated parameters were observed at baseline between groups. Wilcoxon and Mann-Whitney tests were used for statistics. Alpha-error was set 0.05, the power-of-the-study 0.57. No adverse healing response was observed. Six months after, sites treated with ...
Non-contained intrabony defect treated using cerabone®, collprotect® membrane and Straumann® Emdogain® - Dr. T. Schwaar (2 ...
Evaluation of the Effect of Buccolingual and Apicocoronal Positions of Dental Implants on Stress and Strain in Alveolar Bone by Finite Element Analysis
BOSTON, USA: Studies have indicated that individuals with a high body mass index are more prone to developing periodontal disease than other people are. Being overweight or obese might also negatively affect ones response to nonsurgical periodontal therapy. In line with these findings, a recently published study has suggested that overweight or obese patients, particularly men, carrying a certain genetic variant were at an even greater overall risk of developing periodontitis.
MyJournals.org - Science - Displacement in root apex and changes in incisor inclination affect alveolar bone remodeling in adult bimaxillary protrusion patients: a retrospective study (Head & Face Medicine)
Calcium aids in development of strong bones and teeth. It also helps your heart, nerves, and muscles. Calcium deficiency often doesnt show symptoms right away, but leads to serious health problems over time. If calcium consumption isnt enough, your body may use the calcium from your bones instead, leading to bone loss.. Experts also believe that calcium deficiencies may be related to low bone mass and weakening of bones due to osteoporosis.. Calcium deficiency leads to convulsions and abnormal heart rhythm which can be life-threatening. Postmenopausal women experience greater bone loss due to changing hormones experiencing troubles absorbing calcium.The best sources of calcium are dairy products such as milk, yogurt, cheese, calcium-set tofu, and small fish with bones. Vegetables such as kale and broccoli also have calcium, and many cereals and grains are calcium-fortified.. ...
Overall marginal bone loss was not significantly different between the two treatment groups (EHC vs. IHC) at any time point. The mean difference of bone levels between EHC and IHC was 0.25 mm (95% CI: −0.18 to 0.69) at implant placement. Mean difference between IHC and EHC was −0.01 mm (95% CI: −0.34 to 0.36) at 3 months, 0.13 mm (95% CI: −0.48 to 0.22) at 6 months and 0.11 mm (95% CI: −0.45 to 0.25) at 12 months. All the implants showed good periodontal health at the 1-year-in-function visit, with no statistically significant differences between groups. At 12 months mean (± standard deviation) PI was 2 (± 1.5) for the EHC and 1.85 (± 1.58) for the IHC group (P = 0.57) with a mean difference between the two groups of 0.15 (95% CI: −0.56 to 0.85). Mean PD was 2.23 mm (± 0.52) for the EHC and 2.10 mm (± 0.39) for the IHC group (P = 0.39), with a mean difference between the two groups of 0.12 mm (95% CI: −0.08 to 0.33). At 12 months 41.4% of EHC and 43.6% of IHC implants ...
Objective The aim of the present study was to assess interventions and their consequences with regard to further bone loss at sites diagnosed with peri-implantitis. Materials and Methods In 2017, records of 70 patients diagnosed with moderate/severe peri-implantitis at >= 1 implant sites 4 years earlier were obtained. Changes of marginal bone levels during the study period assessed on radiographs and predictors of disease progression were identified by Cox regression and mixed linear modelling. Patient files were analysed for professional interventions related to the treatment of peri-implantitis. Results Mean bone loss (+/- SD) at implants diagnosed with moderate/severe peri-implantitis was 1.1 +/- 2.0 mm over the observation period of 3.3 years. While non-surgical measures including submucosal and/or supra-mucosal cleaning of implants were provided to almost all patients, surgical treatment of peri-implantitis was limited to a subgroup (17 subjects). Surgically treated implant sites ...
The molecular mechanisms controlling the differentiation of bone marrow stromal stem cells into osteoblasts remain mainly unknown. Similar results were found for the knockdown of the receptor- knockdown cells than control cells. Our data provide the first evidence that is involved in the osteogenic differentiation of bone tissue marrow stromal cells the legislation of the signaling pathway. Launch Osteoblasts differentiate from bone tissue marrow stromal cells (BMSCs), also called mesenchymal stem cells, that have the capacity to be adipocytes or fibroblasts [1]. Lately, individual alveolar-derived BMSCs (hAD-BMSCs) have already been effectively isolated and cultured [2]. These cells could be ideal for periodontal bone tissue regenerative medication because marrow bloodstream can be quickly aspirated from alveolar bone tissue during tooth removal and oral implant medical procedures [3, 4]. The bone tissue morphogenetic proteins (BMP) 2 signaling pathway can be an important regulator of ...
Ferreira CEA, Novaes AB Jr, Haraszthy VI, Bittencourt M, Martinelli CB, Luczyszyn SM. A clinical study of 406 sinus augmentations with 100% anorganic bovine bone. J Periodontol 2009;80(12):1920-1927.. Sinus grafting with anorganic bovine bone was performed in 222 patients requiring unilateral sinus grafting and 92 patients requiring bilateral sinus grafting; a total of 1,025 implants were placed (118 simultaneous with grafting and 907 at second stage surgery after 6-12 months). After 3 years, the implant survival rate was 98.1% (19 implants were lost), with no significant differences in survival between implants with rough or machined surfaces, or between implants placed in various heights of native bone. Histomorphometry showed 39.0 ± 12% new bone formation and 52.9% ± 9.3% marrow space.. Song D-W, Lee D-W, Kim C-K, Park K-H, Moon I-S. Comparative analysis of peri-implant marginal bone loss based on microthread location: a 1-year prospective study after loading. J Periodontol ...
Results: One patient (11-mm group) died before the 12-month evaluation and one patient (6-mm group) moved away. In addition, one patient in the 6-mm group lost one implant and no implants were lost in the 11-mm group. Two patients lost three restorations in the 6-mm group and no restorations were lost in the 11-mm group. From loading until the 60-month assessment, the mean marginal bone loss in the 6-mm group and the 11-mm group was 0.12 ± 0.36 mm and 0.14 ± 0.63 mm, respectively, without a significant difference (mean difference 0.02 mm; 95% CI -0.32 to 0.37; P = 0.884). Implant loss, restoration loss, screw loosening and porcelain chipping were defined as complications. Four patients in the 6-mm group and one patient in the 11-mm group had one or more complications, without a significant difference between the groups (95% CI 0.019 to 0.244; P = 0.198). The patient satisfaction was high in both groups (mean overall satisfaction in the 6-mm and the 11-mm groups was 9.4 ± 0.8 and 9.2 ± 0.8, ...
Results: One patient (11-mm group) died before the 12-month evaluation and one patient (6-mm group) moved away. In addition, one patient in the 6-mm group lost one implant and no implants were lost in the 11-mm group. Two patients lost three restorations in the 6-mm group and no restorations were lost in the 11-mm group. From loading until the 60-month assessment, the mean marginal bone loss in the 6-mm group and the 11-mm group was 0.12 ± 0.36 mm and 0.14 ± 0.63 mm, respectively, without a significant difference (mean difference 0.02 mm; 95% CI -0.32 to 0.37; P = 0.884). Implant loss, restoration loss, screw loosening and porcelain chipping were defined as complications. Four patients in the 6-mm group and one patient in the 11-mm group had one or more complications, without a significant difference between the groups (95% CI 0.019 to 0.244; P = 0.198). The patient satisfaction was high in both groups (mean overall satisfaction in the 6-mm and the 11-mm groups was 9.4 ± 0.8 and 9.2 ± 0.8, ...
Cimetidine is a powerful H2 receptor antagonist originally designed to treat ulcers by blocking the acid producing cells in the stomach. In the study three groups of rabbits were simultaneously induced with experimental periodontitis using P. gingivalis and treated with varying levels of topically applied cimetidine three times a week over a six-week period. Results showed that topical application of cimetidine at all concentrations inhibited inflammation and bone loss by approximately 90 ...
The PDL substance has been estimated to be 70% water, which is thought to have a significant effect on the tooths ability to withstand stress loads. The completeness and vitality of the PDL are essential for the functioning of the tooth. The PDL ranges in width from 0.15 to 0.38mm with its thinnest part located in the middle third of the root.[5] The width progressively decreases with age. The PDL is a part of the periodontium that provides for the attachment of the teeth to the surrounding alveolar bone by way of the cementum. The PDL appears as the periodontal space of 0.4 to 1.5 mm on radiographs, a radiolucent area between the radiopaque lamina dura of the alveolar bone proper and the radiopaque cementum. ...
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Zadik Y, Bechor R, Shochat Z, Galor S (April 2008). "[Ethnic origin and alveolar bone loss in Israeli adults]". Refu'at Ha-Peh ... Research has shown that smokers have more bone loss, attachment loss and tooth loss compared to non-smokers. This is likely due ... no evidence of bone loss over last five years Grade B: Moderate progression; < 2mm of bone loss over last five years Grade C: ... Amount and percentage bone loss radiographically Clinical attachment loss, probing depth Presence of furcation Vertical bony ...
"Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice". Journal of Bone and Mineral Research. 32 (5 ... "A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone ...
ISBN 81-89093-10-X. Levin, Liran (June 2007). "Alveolar Bone Loss and Gingival Recession Due to Lip and Tongue Piercing". N Y ... In some cases, the alveolar tooth-bearing bone is also involved, jeopardizing the stability and durability of the teeth in ... Bone, Angie; Fortune Ncube; Tom Nichols; Norman D Noah (21 June 2008). "Body Piercing in England: a Survey of Piercing at Sites ... It was popular among the Aztecs, the Mayans and the tribes of New Guinea, who adorned their pierced noses with bones and ...
Evidence of alveolar bone loss is also required to differentiate between true bone loss and not attributions of gingival oedema ... The cumulative effects of alveolar bone loss, attachment loss and pocket formation is more apparent with an increase in age. ... Usually, a horizontal pattern of bone loss would be found however, vertical (infrabony) bone loss may also be present on ... However, usually when presenting complaints do arise the effects of mobility and alveolar bone loss have become severe. A full ...
Extension of the lesion into alveolar bone, periodontal ligament with significant bone loss Continued loss of collagen ... The disease consists of a chronic inflammation associated with loss of alveolar bone. Advanced disease features include pus and ... drifting and eventual loss Because bone loss makes its first appearance in the advanced lesion, it is equated with ... Features of the Established Lesion: Predominance of plasma cells without bone loss Presence of extravascular immunoglobulins in ...
... all of them exhibited mild to moderate alveolar bone loss resulting from periodontal disease (the wearing away of the bone ... three exhibited no pathologies of the alveolar bone. Measuring the distance between the alveolar bone and the cementoenamel ... Ripamonti, U. (1989). "The Hard Evidence of Alveolar Bone Loss in Early Hominids of Southern Africa". Journal of Periodontology ... the lower part of the upper arm bone), a proximal right ulna (upper part of a lower arm bone) and a distal phalanx bone of the ...
7 exhibited mild to moderate alveolar bone loss resulting from periodontal disease (the wearing away of the bone which supports ... Ripamonti, U. (1989). "The Hard Evidence of Alveolar Bone Loss in Early Hominids of Southern Africa". Journal of Periodontology ... The trabecular bone at the hip joint is distinctly humanlike, which would be inconsistent with the great degrees of hip loading ... The leg bones clearly show that A. africanus habitually engaged in bipedal locomotion, though some aspects of the tibiae are ...
Untreated, these diseases can lead to alveolar bone loss and tooth loss. As of 2013[update], Periodontal disease accounted for ... ongoing chronic stress are more likely to have clinical attachment loss and decreased levels of alveolar bone due to ... In periodontal health, the alveolar bone surrounds the teeth and forms the bony socket that supports each tooth. The buccal and ... encompasses a number of diseases of the periodontal tissues that result in attachment loss and destruction of alveolar bone. ...
This condition increase alveolar bone loss, attachment loss, tooth mobility, and finally tooth loss. It can cause other ... involvement in bone infections: a review". International Journal of Antimicrobial Agents. 41 (6): 509-15. doi:10.1016/j. ...
Untreated, these diseases can lead to alveolar bone loss and tooth loss. As of 2013[update], Periodontal disease accounted for ... Alveolar Bone[edit]. In periodontal health, the alveolar bone surrounds the teeth and forms the bony socket that supports each ... ongoing chronic stress are more likely to have clinical attachment loss and decreased levels of alveolar bone due to ... Alveolar bone D. Oral epithelium E. Attached gingiva F. Gingival margin G. Gingival sulcus H. Junctional epithelium I. Alveolar ...
This may further lead to furcal involvement through loss of clinical attachment and alveolar bone. A cursory clinical ... This is because neutrophils, which are rich sources of PGE2, are present when the majority of rapid bone loss occurs during the ... injured site and cause resorption of the periapical alveolar bone. It is possible that after conventional endodontic therapy ... Regeneration of the bone has been demonstrated to occur, on average, at a rate of 3.2 mm² per month, and studies suggest that ...
... is a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. ... Alveolar bone is the bone that surrounds the roots of the teeth forming bone sockets. In mammals, tooth sockets are found in ... Alveolar ridge Polyphyodont Peck, Mogammad Thabit; Marnewick, Johan; Stephen, Lawrence (2011). "Alveolar Ridge Preservation ... Dental alveoli (singular alveolus) are sockets in the jaws in which the roots of teeth are held in the alveolar process with ...
In advanced cases the alveolar bone loss may be depicted as a horizontal bone loss pattern radiographically. Mostly in ... Loss of attachment refers to the destruction of periodontium whereas the bone refers to the alveolar bone supporting the teeth ... Jonasson G (July 2015). "Five-year alveolar bone level changes in women of varying skeletal bone mineral density and bone ... to the alveolar bone crest is typically in the order of 1mm in young people. If the distance between the ACJ and alveolar bone ...
Mitsis, F.J.; Taramidis, G.(1995) "Alveolar bone loss on neolithic man remains on 38 skulls of Khirokitia's (Cyprus) ...
Julihn A, Barr Agholme M, Modeer T (June 2008). "Risk factors and risk indicators in relation to incipient alveolar bone loss ... If this is not treated, the inflammation will lead to the bone loss and will eventually lead to the affected teeth becoming ... In the group that was instructed to rinse with saline, the prevalence of alveolar osteitis was less than in the group that did ... Severe gum disease causes at least one-third of adult tooth loss. Since before recorded history, a variety of oral hygiene ...
... the alveolar ridge has a mean loss of width of 3.8mm, and a height loss of 1.24mm within six months. This loss of bone volume, ... loss in bone volume in the first six months. Bone loss, can compromise the ability to place a dental implant (to replace the ... Socket preservation or alveolar ridge preservation is a procedure to reduce bone loss after tooth extraction. After tooth ... Socket preservation attempts to prevent bone loss by bone grafting the socket immediately after extraction. With the procedure ...
Effect of dietary vitamin E supplement and rotational stress on alveolar bone loss in rice rats (subscription required). ... Effect of stannous fluoride and iodine on root caries and bone loss in rats. Ohio Journal of Science 88(3):99-100. Benson, D.E ... Vitamin E, fluoride, and iodide protect against bone loss associated with this disease in the rice rat and a high-sucrose diet ... The nasal and premaxillary bones extend back beyond the point where the lacrimal, frontal, and maxillary bones meet. In P. o. ...
They describe the development of lateral plates on the alveolar margins of tooth-bearing bones. These plates can be used to ... strip foliage, the eusauropod's "U-shaped" jaws create a wide bite, and their loss of "fleshy cheeks" increased the gape. The ... Unlike prosauropods and theropods, which have a snout with smooth, unprotruding alveolar and subnarial regions, eusauropods ...
... gingival recession and alveolar bone loss. Therefore, thorough cleaning with a toothbrush, toothpaste and interdental cleaning ... the surrounding periodontal fibres adapt to changes in the bone which can help minimize any changes to the final tooth position ...
Interproximal and horizontal alveolar bone loss in mouse models are seen in coinfections involving P. gingivalis and Treponema ... Vaccines made from P. gingivalis CPS apparently impair oral bone loss in murine models. These vaccines have been able to elicit ... In contrast, germ free mice inoculated with a P. gingivalis monoinfection incur no bone loss, indicating that P. gingivalis ... In these models, P. gingivalis inoculation causes significant bone loss, which is a significant characteristic of the disease. ...
Stippling only presents on the attached gingiva bound to underlying alveolar bone, not the freely moveable alveolar mucosaor ... unless it is smooth due to a loss of previously existing stippling. Stippling is a consequence of the microscopic elevations ...
Some loss of connective tissue attachment and alveolar bone loss is normal during a 2-year course of orthodontic treatment. ... Tooth loss implies in loss of several orofacial structures, such as bone tissues, nerves, receptors and muscles and ... Dental abscesses can cause resorption of bone and consequent loss of attachment. Depending on the type of abscess, this loss of ... Severe infection at the apex of a tooth can again result in bone loss and this in turn can cause mobility. Depending on the ...
They are also attached to the gingival (gum) tissue that covers the alveolar bone by an attachment apparatus; because this ... Teeth are attached to the surrounding and supporting alveolar bone by periodontal ligament (PDL) fibers; these fibers run from ... of the alveolar bone, it is termed the supracrestal attachment apparatus. The supracrestal attachment apparatus is composed of ... Connective tissue attachment loss refers to the pathological detachment of collagen fibers from cemental surface with the ...
If done successfully, it is able to ensure stable alveolar bone volume as there is continuous stimulation of the periodontal ... At present, it has been theorised that evolutionary change is working to decrease the human dentition by the loss of an incisor ... The primary molars present also functions as a space maintainer, prevent alveolar bone resorption and delays future ... However, bone grafting can be carried out to overcome this. Hypodontia is less common in the primary dentition with reported ...
This condition increase alveolar bone loss, attachment loss, tooth mobility, and finally tooth loss.[4] It can cause other ... involvement in bone infections: a review. Int J Antimicrob Agents. 2013 Jun;41(6):509-15. ...
... gingival recession and loss of alveolar bone crest height. In these cases, crown lengthening surgery should be considered. ... Secondly, the biologic width, the mandatory distance (roughly 2 mm) to be left between the height of the alveolar bone and the ... potentially resulting in the loss of healthy, natural tooth structure for this purpose, the all-porcelain CAD/CAM crown can be ... sound tooth structure may need to be sacrificed in order to prevent further more substantial and uncontrolled loss of tooth ...
Alveolar crest fibers (I) run from the cervical part of the root to the alveolar bone crest Horizontal fibers (J) attach to the ... All of these can lead to loss of vitality of the PDL and depending on the duration of storage, this can affect the success of ... bone remodelling is initiated by the PDL in which forces are transmitted from the tooth to the alveolar bone. Fibroblasts of ... The PDL is a part of the periodontium that provides for the attachment of the teeth to the surrounding alveolar bone by way of ...
Patients often present with early-onset aggressive periodontitis associated with advanced alveolar bone loss and tooth mobility ... Bone marrow transplants appear to have been successful in several patients. Infections are treated with antibiotics and ... The diagnosis is confirmed by bone marrow smears that show "giant inclusion bodies" in the cells that develop into white blood ...
"Bone Marrow Transplant" redirects here. For the journal abbreviated Bone Marrow Transplant, see Bone Marrow Transplantation ( ... In the case of allogeneic transplants, fresh HSC are preferred in order to avoid cell loss that might occur during the freezing ... alveolar hemorrhage, and allergic reactions (usually expressed in first 30 minutes, risk 1 in 300).[43][44][45] In addition, ... In the case of a bone marrow transplant, the HSC are removed from a large bone of the donor, typically the pelvis, through a ...
This injury involves the alveolar bone and may extend beyond the alveolus.[5][6] There are 5 different types of alveolar ... Trauma is the most common cause of loss of permanent incisors in childhood. Dental trauma often lead to the main complication ... Dental trauma refers to trauma (injury) to the teeth and/or periodontium (gums, periodontal ligament, alveolar bone), and ... tooth should be gently rinsed under tap water and immediately re-planted in its original socket within the alveolar bone and ...
The damage to the endothelium and the alveolar epithelium results in the creation of an open interface between the lung and the ... Fluid filled airspaces, loss of surfactant, microvascular thrombosis and disorganized repair (which leads to fibrosis) reduces ... This agent also causes respiratory tract lesions, bone marrow depression, and eye damage, the epithelial tissues of these ... Uchida T, Makita K. (2008) Acute lung injury and alveolar epithelial function. Masui. 57:51-9. Tang PS, Mura M, Seth R, Liu M ...
Ears: conductive hearing loss due to auditory tube dysfunction, sensorineural hearing loss (unclear mechanism) ... Oral cavity: strawberry gingivitis, underlying bone destruction with loosening of teeth, non-specific ulcerations throughout ... such as diffuse alveolar hemorrhage, glomerulonephritis (as seen in pulmonary-renal syndrome), or mesenteric ischemia, are ... hearing loss, and deafness.[11] The risk of relapse is increased in people with GPA who test positive for anti-PR3 ANCA ...
The main symptoms and signs of a skin abscess are redness, heat, swelling, pain, and loss of function. There may also be high ...
Except for its loss from the state of South Australia, the platypus occupies the same general distribution as it did prior to ... However, the external opening of the ear still lies at the base of the jaw.[15] The platypus has extra bones in the shoulder ... which are kidney-shaped alveolar glands connected by a thin-walled duct to a calcaneus spur on each hind limb. The female ... the tiny bones that conduct sound in the middle ear are fully incorporated into the skull, rather than lying in the jaw as in ...
The finger bones of bats are much more flexible than those of other mammals, owing to their flattened cross-section and to low ... In bats, the relative alveolar surface area and pulmonary capillary blood volume are larger than in most other small ... and this loss may derive from a common bat ancestor, as a single mutation.[133][b] At least two species of bat, the frugivorous ... The patagium is the wing membrane; it is stretched between the arm and finger bones, and down the side of the body to the hind ...
Other common causes of low hemoglobin include loss of blood, nutritional deficiency, bone marrow problems, chemotherapy, kidney ... Newton DA, Rao KM, Dluhy RA, Baatz JE (2006). "Hemoglobin Is Expressed by Alveolar Epithelial Cells". Journal of Biological ... Even after the loss of the nucleus in mammals, residual ribosomal RNA allows further synthesis of Hb until the reticulocyte ... Other cells that contain haemoglobin include the A9 dopaminergic neurons in the substantia nigra, macrophages, alveolar cells, ...
Sudden cabin pressure loss activates chemical oxygen generators above each seat, causing oxygen masks to drop. Pulling on the ... and bone. Most of the mass of living organisms is oxygen as a component of water, the major constituent of lifeforms. Oxygen is ... Alveolar pulmonary. gas pressures. Arterial blood oxygen. Venous blood gas kPa. 14.2. 11[75]-13[75]. 4.0[75]-5.3[75] ... 2 at higher than normal pressure and a spark led to a fire and the loss of the Apollo 1 crew. ...
Sudden cabin pressure loss activates chemical oxygen generators above each seat, causing oxygen masks to drop. Pulling on the ... and bone. Most of the mass of living organisms is oxygen as a component of water, the major constituent of lifeforms. Oxygen is ... Alveolar pulmonary. gas pressures. Arterial blood oxygen. Venous blood gas kPa. 14.2. 11[75]-13[75]. 4.0[75]-5.3[75]. ... 2 at higher than normal pressure and a spark led to a fire and the loss of the Apollo 1 crew. ...
This theory is based on the fact that, during galloping, the absence of any bone attachment of the forelegs to the spine in the ... Hemosiderophages are alveolar macrophages that have ingested and digested red blood cells from previous episodes of EIPH. The ... with consequent loss of lung function. ...
It is attached to the alveolar bone (C) by the fibers of the periodontal ligament and to the soft tissue of the gingiva by the ... resulting in restorative obstacles and increased tooth loss.[2] ... Thus again, cementum is more similar to alveolar bone, with its ... The cementum is the part of the periodontium that attaches the teeth to the alveolar bone by anchoring the periodontal ligament ... Unlike those in bone, however, these canals in cementum do not contain nerves, nor do they radiate outward. Instead, the canals ...
Periapical, mandibular and maxillary hard tissues - Bones of jaws. *Agnathia. *Alveolar osteitis ...
Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1) ... The most typical disorder induced by thalidomide were reductional deformities of the long bones of the extremities. Phocomelia ... Chromosomal disorders involve the loss or duplication of larger portions of a chromosome (or an entire chromosome) containing ... shortness of the 4th metacarpal or metatarsal bones, or dimples over the lower spine (sacral dimples). Some minor anomalies may ...
Periapical, mandibular and maxillary hard tissues - Bones of jaws. *Agnathia. *Alveolar osteitis ... Deardorff J (March 5, 2014). "Loss of canker sore toothpaste angers loyal users". Chicago Tribune. Retrieved April 12, 2014.. ... In severe cases, this prevents adequate nutrient intake leading to malnutrition and weight loss.[3] ... The severe forms may be debilitating, even causing weight loss due to malnutrition. ...
The juvenile, acute form is characterised by symptoms, such as fever, weight loss and feeling unwell together with enlarged ... and bone involvement may occur in severe cases.[10] This acute, severe presentation may mimic tuberculosis, lymphoma or ... whereas in the chronic form plain X-rays may show interstitial and alveolar infiltrates in the central and lower lung fields.[ ...
The mental nerve is a branch of the mandibular branch ( via the inferior alveolar nerve). It supplies the skin and mucous ... People who have hearing loss may unconsciously or consciously lip read to understand speech without needing to perceive the ... Clevosaurids like Clevosaurus are notable for the presence of bone "lips"; in these species the tooth-like jaw projections ...
The resultant alveolar rupture can lead to pneumothorax, pulmonary interstitial emphysema (PIE) and pneumomediastinum.[26] ... Mechanical trauma to the inner ear can lead to varying degrees of conductive and sensorineural hearing loss as well as vertigo ... Brain and cranium (temporal lobe injury secondary to temporal bone rupture)[11] ... Bason, R.; Yacavone, D. W. (May 1992). "Loss of cabin pressurization in U.S. Naval aircraft: 1969-90". Aviation, Space, and ...
Periapical, mandibular and maxillary hard tissues - Bones of jaws. *Agnathia. *Alveolar osteitis ... The main cause of DH is gingival recession (receding gums) with exposure of root surfaces, loss of the cementum layer and smear ... especially in areas of periodontal attachment loss.[9] ...
There is almost complete loss of final syllables and very widespread loss of other unstressed syllables (e.g. mik, 'friend' ... In most of the dialects, as also in standard Albanian, the single "r" changes from an alveolar flap /ɾ/ into a retroflex flap [ ... h₂osti 'bone'. asht 'bone' th[* 8]. *suh₁s 'swine'. thi 'boar' ... ɽ], or even an alveolar approximant [ɹ] when it is at the end of a word. ...
WITHDRAWNCalcium supplementation on bone loss in postmenopausal women PMID 17636765 https://doi.org/10.1002/14651858.CD004526. ... Interventions for iatrogenic inferior alveolar and lingual nerve injury PMID 24740534 https://doi.org/10.1002/14651858.CD005293 ... Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant treatment ... Processed versus fresh frozen bone for impaction bone grafting in revision hip arthroplasty PMID 19821362 https://doi.org/ ...
In these animals, it causes hair loss, though the nature and distribution of the hair loss differs greatly.[46] ... "The effect of 5alpha-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, ... Lars Mecklenburg; Monika Linek; Desmond J. Tobin (15 September 2009). Hair Loss Disorders in Domestic Animals. John Wiley & ...
One of the advantages of a full-face diving mask is prevention of regulator loss in the event of a seizure. As there is an ... high oxygen concentrations may contribute to bone damage.[14] Hyperoxia can also indirectly cause carbon dioxide narcosis in ... with evidence of diffuse alveolar damage and the onset of acute respiratory distress syndrome usually occurring after 48 hours ...
14 Middle Korean has /je-(sɨs)/ "6", which may fit here, but the required loss of initial /nʲ/- "is not quite regular" ( ... bone', 'blood', 'water', 'stone', 'sun', and 'two'.[23] This work has not changed the minds of any of the principal authors in ... Alveolar or dental. Alveolopalatal. Postalveolar. Palatal Velar Plosives. aspirated. /pʰ/. /tʰ/. /kʰ/. ... They reasoned that, if all three families had a common ancestor, we should expect losses to happen at random and not only at ...
10). It consisting of the alveolar epithelial cells, their basement membranes and the endothelial cells of the alveolar ... It is formed by a vascularized expansion of the epibranchial bone of the first gill arch, and is used for respiration in air.[ ... along with coordinated spiracle contraction and relaxation to generate cyclical gas exchange patterns and to reduce water loss ... changing the composition of the 3 liters of alveolar air slightly. Similarly, since the blood arriving in the alveolar ...
Injection methodology: The periodontal ligament space provides an accessible route to the cancellous alveolar bone, and the ... When it is used on specific nerve pathways (local anesthetic nerve block), paralysis (loss of muscle power) also can be ... Bone and joint surgery of the pelvis, hip, and leg (spinal/epidural anesthesia, peripheral nerve blocks, or intravenous ... This thereby results in enhanced hydrodynamic diffusion of solution into bone or the target area of deposition,[49][50] thus ...
Periapical, mandibular and maxillary hard tissues - Bones of jaws. *Agnathia. *Alveolar osteitis ...
Immune responses to infection trigger loss of alveolar bone from the jaw and eventual tooth loss. We investigated the ... B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection. Pamela J. Baker,1 Nicole Ryan Boutaugh,1 ... contribution of B cell IgD to alveolar bone loss by comparing the response of B cell normal BALB/cJ mice and IgD deficient BALB ... Specific antibody to P. gingivalis was lower and oral colonization was higher in IgD deficient mice; yet bone loss was ...
"Alveolar Bone Loss" by people in Harvard Catalyst Profiles by year, and whether "Alveolar Bone Loss" was a major or minor topic ... Annual alveolar bone loss in older adults taking oral bisphosphonate: a retrospective cohort study. BMC Oral Health. 2019 11 27 ... "Alveolar Bone Loss" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Prevalence of periodontitis and alveolar bone loss in a patient population at Harvard School of Dental Medicine. BMC Oral ...
Systemic administration of Morus nigra significantly inhibited the regional alveolar bone resorption and contributes to ... and alveolar bones were evaluated histopathologically and histometrically analyzed to obtain level of alveolar bone loss. The ... The effects of morus nigra on the alveolar bone loss in experimentally-induced periodontitis. ... alveolar bone loss was greater in the PER group compared to C and MN groups (p=0.035). Immuno-histochemical staining of RANKL ...
403 Bis-enoxacin Inhibited Alveolar Bone Loss and Gingival Inflammation in Rats Thursday, March 22, 2012: 2 p.m. - 3:15 p.m. ... and alendronate in inhibiting osteoclast alveolar bone resorption (ABR) in a polymicrobial periodontal disease rat model. ... Similarly, enoxacin-linked bisphosphonate, bis-enoxacin, inhibits osteoclast formation and bone resorption. Periodontal ...
Quantify periodontal alveolar bone loss rates in postmenopausal women.. II. Evaluate the effects of estrogen on alveolar bone ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. The safety and ... Comparison of reliability of manual and computer-intensive methods for radiodensity measures of alveolar bone loss. ... loss rates in these patients.. III. Determine whether changes in periodontal bone mass relate to bone mass changes in other ...
Quantify periodontal alveolar bone loss rates in postmenopausal women.. II. Evaluate the effects of estrogen on alveolar bone ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. The safety and ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. ... Comparison of reliability of manual and computer-intensive methods for radiodensity measures of alveolar bone loss. ...
... severe alveolar bone loss ranging between 1/3 and 2/3 of the normal alveolar bone height (group 4), or alveolar bone loss ... gingivitis without signs of alveolar bone loss (group 2), moderate alveolar bone loss not exceeding 1/3 of the normal alveolar ... Mean alveolar bone loss varied between 1.51 mm and 2.64 mm depending on smoking status and age. Mean alveolar bone loss was ... Alveolar bone loss was recorded if the distance from the cemento-enamel junction to the alveolar crest exceeded 2 mm measured ...
The mean alveolar bone difference was 5.5 per cent of the mean root length, which corresponds to an average bone loss of 0.09 ... The progression of proximal alveolar bone loss (ABD index) in an unselected material comprising 406 individuals was analysed by ... the alveolar bone loss 1970 (ABL index 1970), Age, Number of lost teeth and Russells Periodontal Index (PI). The ... Proximal alveolar bone loss in a longitudinal radiographic investigation. https://arctichealth.org/en/permalink/ ...
... deterioration of the mandibular bone and a potential alveolar bone loss needs to be considered regardless whether other signs ... Deterioration of teeth and alveolar bone loss due to chronic environmental high-level fluoride and low calcium exposure. Author ... Categories: Bones/Joints, Bone Density, Bone Mineralization/Quality, Susceptible Populations, Nutritional Status, Calcium ... Therefore, we studied the tooth and alveolar bone structures of Dorper sheep chronically exposed to very highly fluoridated and ...
Effect of Ratio of Residual Alveolar Bone to Graft Material in Contact With Fixture Surface on Marginal Bone Loss of Implants ... The residual bone/implant length ratio and the residual bone/implant area ratio were not associated with marginal bone loss at ... The residual bone/implant length ratio and residual bone/implant area ratio were not associated with marginal bone loss around ... study was to evaluate the influences of height or area ratio of residual alveolar bone to graft material on marginal bone loss ...
... ... as well as severe hypertension and alveolar bone loss (ABL) in older adults. ... Direct measures of alveolar bone level were recorded using CT scans, and different variables were studied (age, sex, Plaque ... The results confirmed a positive association between CHD/VD and periodontal destruction; alveolar bone destruction represented ...
... Grethe Jonasson, Marianne Rythén*Clinical Cosmetic and ...
... fusing to your own alveolar ridge bone. Not all patients are good candidates for ridge augmentation bone grafting. If you or ... The alveolar ridge of the jaw is the bone that surrounds the roots of teeth. When a tooth is removed an empty socket is left in ... This procedure helps recreate the natural contour of the gums and jaw that may have been lost due to bone loss from a tooth ... the alveolar ridge bone. Usually this empty socket will heal on its own, filling with bone and tissue. Sometimes when a tooth ...
Effect of caloric restriction on alveolar bone loss in rats *Evelyn Lopez Soares ... Bone mineral density and Hounsfield unit measurements were obtained using Microwave Software ABA (Advanced Bone Analysis), ... is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss. J. Exp. Med. 201, 1677-1687 ( ... Values of Hounsfield units (HU) and bone mineral density (BMD) for all the femurs are shown. (c) Wound-healing assay in ⩾2-year ...
Targeting NLRP3 Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss. Y. Zang, J. H. Song, S. H. Oh, J. W. Kim, M. ... Targeting NLRP3 Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss. / Zang, Y.; Song, J. H.; Oh, S. H.; Kim, J. W ... Our results suggest that the NLRP3 inflammasome is a critical mediator in age-related alveolar bone loss and that targeting the ... Our results suggest that the NLRP3 inflammasome is a critical mediator in age-related alveolar bone loss and that targeting the ...
Morphometric registration of alveolar bone loss was carried out after 30 days of ligature placement to determine the effect of ... Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental ... Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental ... Effect of obesity on alveolar bone loss in experimental periodontitis in Wistar rats. ...
Re-imagining discovery and access to research: grants, datasets, publications, citations, clinical trials, patents and policy documents in one place.
... does demonstrate the anatomical changes that occur in the alveolar bone ridge of the maxillary bone after the loss of teeth, ... KEY WORDS: Anatomy; Maxilla; Total prosthesis; Alveolar bone loss; Dental implantation.. RESUMEN: Este estudio propuso medir y ... In conclusion, as the tooth loss occurs, irreversible anatomical changes take place in the maxillary bone, occurring alveolar ... A. Alveolar ridge (AR) to the anterior nasal spine (ANS), B. Alveolar ridge (AR) to the incisive foramen (IF), C. Alveolar ...
... ... induced hydroxyapatite loss in rat alveolar bone. Rats were divided into four groups. The animals injected with saline or ... the present study suggests that oral treatment with fish oil may reduce LPS-induced hydroxyapatite loss in rat alveolar bone ... The results of the present study showed that the hydroxyapatite contents of alveolar bone in rats treated with fish oil at the ...
These results suggest that levels aluminum in the blood and alveolar bone induce alveolar bone loss, besides present ... we evaluated the concentration of Al in the blood and alveolar bone, as well as the Al measurement in alveolar bone. The ... Here, we investigated the effects of sub-chronic intoxication with Al citrate in a model of alveolar bone loss, induced by ... The Al exposure per si results in alveolar bone loss as well as potentiates damages of periodontitis induced cases. ...
Alveolar bone lossAlveolar bone levels are evaluated by clinical and radiographic examination. • Probing is helpful for ... The periodontal pocket is a soft tissue change • Radiographs indicate areas of bone loss where pockets may be suspected but : 1 ... Changes in the level of attachment can be due only to gain or loss of attachment and afford a better indication of the degree ... If both are the same, the loss of attachment is zero • When the gingival margin coincides with the cementoenamel junction, the ...
Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar ... Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar ... Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar ... Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar ...
Results: The measurements of alveolar bone loss in the mandibular molars revealed significantly higher bone-loss values in the ... Alveolar bone loss was measured. Interleukin 1 beta (IL-1 beta) and interleukin 10 (IL-10) were evaluated in the serum samples ... The aim of this study was to evaluate the effects of systemic curcumin therapy on alveolar bone loss in an experimental ... Effects of Curcumin on Alveolar Bone Loss in Experimental Periodontitis in Rats: A Morphometric and Histopathologic Study ...
Alveolar Bone Loss. *Bad Taste in Mouth. *Black Hairy Tongue. *Bonding Disorders ...
Burton frequently treats Abscess, Alveolar Bone Loss, and Clicking of Temporomandibular Joint. See all procedures and ...
Bone Loss, Alveolar Tooth Loss Bone Atrophy, Alveolar Procedure: AUTOTRANSPLANTATION TOOTH Not Applicable ... Alveolar Bone Loss. Tooth Loss. Atrophy. Pathological Conditions, Anatomical. Periodontal Diseases. Mouth Diseases. ... Change in alveolar bone 12 months after tooth autotransplantation [ Time Frame: 1 year ]. CT-scan evaluation before surgery and ... Tooth Autotransplantation and Bone Dimension Changes. The safety and scientific validity of this study is the responsibility of ...
... the periodontal ligament and alveolar bone). It is highly prevalent... ... pattern of bone loss. Some of the teeth have lost nearly all their supporting alveolar bone as a result of periodontitis ... Alveolar bone levels are normal, with the crest of the alveolar bone being in close proximity to the cemento-enamel junction ( ... Risk indicators for alveolar bone loss. J Periodontol 66:23-29PubMedCrossRefGoogle Scholar ...
DR could be a supplementary medicine for periodontal therapy as it could reduce bone resorption in rat model of alveolar bone ... Objective: To investigate if Drynariae rhizoma (DR) and its main ingredient Naringin could reduce alveolar bone loss by ... DR could be a supplementary medicine for periodontal therapy as it could reduce bone resorption in rat model of alveolar bone ... Osteogenic effect of Drynariae rhizoma extracts and Naringin on MC3T3-E1 cells and an induced rat alveolar bone resorption ...
Alveolar Bone Loss/chemically induced , Alveolar Bone Loss/drug effects , Alveolar Process/drug effects , Alveolar Process/ ... These findings indicate that heavy chronic alcohol exposure from adolescent to adulthood can induce alveolar bone loss in rats ... Alveolar Bone Loss / Age Factors / Rats, Wistar Language: English Journal: Indian J Exp Biol Year: 2015 Type: Article ... Alveolar Bone Loss / Age Factors / Rats, Wistar Language: English Journal: Indian J Exp Biol Year: 2015 Type: Article ...
... bone loss with a doubling of the probability ratios of CHD compared to those at 7.5% bone loss. Conclusions: To our knowledge, ... bone loss with a doubling of the probability ratios of CHD compared to those at 7.5% bone loss. Conclusions: To our knowledge, ... bone loss with a doubling of the probability ratios of CHD compared to those at 7.5% bone loss. Conclusions: To our knowledge, ... bone loss with a doubling of the probability ratios of CHD compared to those at 7.5% bone loss. Conclusions: To our knowledge, ...
  • Zoizner R, Arbel Y, Yavnai N, Becker T, Birnboim-Blau G. Effect of orthodontic treatment and comorbidity risk factors on interdental alveolar crest level: A radiographic evaluation. (harvard.edu)
  • Proximal alveolar bone loss in a longitudinal radiographic investigation. (arctichealth.org)
  • Currently, ligature -induced periodontitis in rats is the main model used in periodontal research , in this model, alveolar bone loss (ABL) is the main parameter evaluated by radiographic, morphometric, and histological techniques . (bvsalud.org)
  • To the best of our knowledge, no study has reported radiographic alveolar bone loss (RABL) associated with betel quid chewing. (ncku.edu.tw)
  • The aim of this report is to highlight the clinical, radiographic, and histological outcomes following use of a bilayer xenogeneic collagen matrix (XCM) in combination with freeze-dried bone allograft (FDBA) for ARP. (hindawi.com)
  • Radiographic and clinical assessment indicated adequate volume of bone for implant placement, with all planned implants placed in acceptable positions. (hindawi.com)
  • II Alveolar bone loss: radiographic findings. (thejcdp.com)
  • Papillon Lefevre Syndrome is an autosomal recessive disorder.1 Clinical presentation include palmoplantar keratoderma with a rapidly progressive periodontal disease.2 This may lead to premature loss of both the deciduous and permanent dentitions.2 Characteristic radiographic features include generalized horizontal and vertical bone loss with a classical "floating in air" appearance. (thefreelibrary.com)
  • Radiographic features include generalized severe bone loss. (thefreelibrary.com)
  • CONCLUSIONS: The current study suggests that chronic environmental fluoride exposure with levels above the recommended limits in combination with low calcium uptake can cause significant attrition of teeth and a significant impaired mandibular bone quality. (fluoridealert.org)
  • The alveolar ridge of the jaw is the bone that surrounds the roots of teeth. (thompsonoralsurgery.com)
  • Periodontitis is a common chronic inflammatory disease characterised by destruction of the supporting structures of the teeth (the periodontal ligament and alveolar bone). (springer.com)
  • Periodontal disease is a microbially-mediated inflammatory disease of tooth-supporting tissues that leads to bone and tissue loss around teeth. (nature.com)
  • Periodontitis is an inflammatory disease triggered by a microbial dysbiosis that affects the supporting tissues around teeth and it eventually leads to tooth loss if left untreated. (nature.com)
  • It minimizes gum tissue loss, leaving more tissue in place to protect the teeth. (prweb.com)
  • This helps the teeth attach more firmly to the bone, making tooth loss less likely. (prweb.com)
  • Periodontal diseases are chronic inflammatory diseases that result in both loss of attachment between teeth and periodontium and osteoclastic resorption of alveolar bone [ 1 ]. (hindawi.com)
  • Periodontal disease in the anterior teeth was defined as per arch sum of maximum pocket depth per tooth and sum of teeth with any alveolar bone loss in the anterior sextants. (ada.org)
  • The authors used these mixed-effects linear models to calculate the progression of periodontitis (the sum of maximum pocket depths and number of teeth with alveolar bone loss) in each arch. (ada.org)
  • Generally all gingival diseases share common features such as signs and symptoms being restricted to gingiva, clinically detectable inflammation, and the potential for the gum tissues to return to a state of health once the cause is removed, without irreversible loss of attachment of the teeth. (wikipedia.org)
  • Hunt EE Jr, Gleiser I (1955) The estimation of age and sex of preadolescent children from bones and teeth. (springer.com)
  • Haavikko K (1970) The formation and the alveolar and clinical eruption of the permanent teeth. (springer.com)
  • Alveolar bone loss of maxillary anterior teeth in adult orthodontic patients. (thejcdp.com)
  • All the remaining teeth had no bone support. (thefreelibrary.com)
  • In its more serious form, called periodontitis, the gums can pull away from the tooth, bone can be lost, and the teeth may loosen or fall out. (wikipedia.org)
  • Diagnosis is by inspecting the gum tissue around the teeth both visually and with a probe and X-rays looking for bone loss around the teeth. (wikipedia.org)
  • The periodontium consists of four tissues: gingiva, or gum tissue, cementum, or outer layer of the roots of teeth, alveolar bone, or the bony sockets into which the teeth are anchored, and periodontal ligaments (PDLs), which are the connective tissue fibers that run between the cementum and the alveolar bone. (wikipedia.org)
  • Ultimately, from a broader perspective, our application of LIV on the teeth seeks to explore the potential benefits of brushing teeth with an electric toothbrush, to not only clean teeth, but also to maintain healthy teeth caused by LIV, in order to improve the quantity and quality of the alveolar bone. (suny.edu)
  • Extensive edentulism or loss of teeth affects the choice of food and causes weight loss and difficulty in communication. (medindia.net)
  • Periodontitis causes loss of alveolar bones leading to loosening and loss of teeth. (medindia.net)
  • Bundle bone is a histologic term for the portion of the bone of the alveolar process that surrounds teeth and into which the collagen fibers of the periodontal ligament are embedded. (wikipedia.org)
  • The inferior alveolar nerve and artery, after traveling through the mandibular foramen, exit at the mental foramen as the mental nerves and vessels which innervate the lower teeth, lip, gingiva and lower face. (ispub.com)
  • After 21 days, the rats were sacrificed, and alveolar bones were evaluated histopathologically and histometrically analyzed to obtain level of alveolar bone loss. (greenmedinfo.com)
  • Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental periodontitis in rats. (ufrgs.br)
  • Conclusions: In spite of the weak differences, it is possible to conclude that the progression of alveolar bone loss in ligature-induced periodontitis can be potentially influenced by body weight in rats. (ufrgs.br)
  • The results of the present study showed that the hydroxyapatite contents of alveolar bone in rats treated with fish oil at the same day with or before LPS injection were significantly higher than those in rats injected with LPS alone, but still lower than those in untreated animals. (unej.ac.id)
  • Here, we investigated the effects of sub-chronic intoxication with Al citrate in a model of alveolar bone loss , induced by ligature , in male Wistar rats . (bvsalud.org)
  • This study has aimed at evaluating the effect of Andrographolide (AND) on alveolar bone resorption in rats induced by Pg . (hindawi.com)
  • We can conclude that AND suppresses alveolar bone resorption caused by Pg in rats. (hindawi.com)
  • It stimulates bone resorption in rat calvaria cultures via its lipopolysaccharide [ 6 ] and causes osteoclastic bone resorption in the hind paws of mice and alveolar bone resorption in rats [ 7 ]. (hindawi.com)
  • Biochanin A alleviates gingival inflammation and alveolar bone loss in rats with experimental periodontitis. (greenmedinfo.com)
  • Intermittent administration of parathyroid hormone ameliorated alveolar bone loss in experimental periodontitis in streptozotocin-induced diabetic rats. (nih.gov)
  • Oral administration of 5-hydroxytryptophan aggravated periodontitis-induced alveolar bone loss in rats. (nih.gov)
  • Mandibles and femurs of the rats were extracted and bone mineral density of the extracted specimens were determined. (scielo.cl)
  • Alveolar bone loss was measured on bite-wing radiographs. (arctichealth.org)
  • The best alternative in periapical radiographs to measuring the alveolar bone height in relation to the root length was to measure it in relation to the tooth length. (arctichealth.org)
  • Methods: Digital panoramic radiographs were used to assess alveolar bone loss (ABL) using a Schei ruler. (elsevier.com)
  • Photostimulable-phosphor, posterior bitewing radiographs were taken to assess alveolar bone. (nih.gov)
  • 2 The height of the alveolar bone margin and the shape and form of its outline are also examined with radiographs. (ispub.com)
  • 3 Biochemical markers can detect inflammatory changes in short period of time where as longer period is required to detect measurable changes in bone density using radiographs. (ispub.com)
  • The articdle presents information on a study which investigated bone level changes determined from periapical radiographs made at annual recall visits of patients for up to nine years after implant placement. (ebscohost.com)
  • Periodontal diseases include gingivitis (in which the inflammation is confined to the gingiva, and is reversible with good oral hygiene) and periodontitis (in which the inflammation extends and results in tissue destruction and alveolar bone resorption). (springer.com)
  • The supporting tissues are known as the periodontium, which includes the gingiva (gums), alveolar bone, cementum, and the periodontal ligament. (amfs.com)
  • The periodontium is composed of alveolar bone, periodontal ligament, cementum and gingiva. (wikipedia.org)
  • The tissues that sit above the alveolar bone crest are considered the free gingiva. (wikipedia.org)
  • [4] Collagen fibres bind the attached gingiva tightly to the underlying periodontium including the cementum and alveolar bone and varies in length and width, [4] depending on the location in the oral cavity and on the individual. (wikipedia.org)
  • Anatomically the periodontium is composed of the gingiva (gum), cementum, periodontal ligament, and alveolar supporting bone. (veterinarypartner.com)
  • To investigate if Drynariae rhizoma (DR) and its main ingredient Naringin could reduce alveolar bone loss by stimulating the proliferation and differentiation of osteoblasts. (nih.gov)
  • The findings of this study provide morphologic and histologic evidence that propolis, when administered systemically, prevents alveolar bone loss in the rat model. (ovid.com)
  • Subgingival microorganisms (those that exist under the gum line) colonize the periodontal pockets and cause further inflammation in the gum tissues and progressive bone loss. (wikipedia.org)
  • T cell-produced cytokines play a pivotal role in the bone loss caused by inflammation, infection, and estrogen deficiency. (jci.org)
  • Analysis of the in vivo effects of IFN-γ in 3 mouse models of bone loss - ovariectomy, LPS injection, and inflammation via silencing of TGF-β signaling in T cells - reveals that the net effect of IFN-γ in these conditions is that of stimulating bone resorption and bone loss. (jci.org)
  • Under conditions of estrogen deficiency, infection, and inflammation, the net balance of these 2 opposing forces is biased toward bone resorption. (jci.org)
  • Stage 1 gingivitis occurs when there is inflammation only without loss of the tooth's support. (veterinarypartner.com)
  • Early Periodontitis Progression of the gingival inflammation into the deeper periodontal structures and alveolar bone crest, with slight bone loss. (studystack.com)
  • The inflammation results in the progressive destruction of the periodontal tissues, leading to attachment loss. (vin.com)
  • Ankylosis is an anomaly of tooth eruption characterized by the fusion of cementum and alveolar bone, and may affect from small regions to the entire root surface. (scielo.cl)
  • Advanced periodontitis can cause damage to the gums, the alveolar bone, and other supportive connective tissue. (prweb.com)
  • The soft tissues and connective fibres that cover and protect the underlying cementum, periodontal ligament and alveolar bone are known as the gingivae. (wikipedia.org)
  • Collagen type III-positive connective tissue resembling periodontal ligament and tooth root structures were present at the interface of bioengineered tooth and bone tissues. (mendeley.com)
  • There is usually a slight loss of connective tissue attachment and alveolar bone. (studystack.com)
  • A band of connective tissue that connects the calf muscle to the heel bone. (harvard.edu)
  • RESULTS: Mean alveolar bone loss varied between 1.51 mm and 2.64 mm depending on smoking status and age. (arctichealth.org)
  • Mean alveolar bone loss was lowest in non-smokers and highest in current smokers. (arctichealth.org)
  • Given identical smoking status, the mean alveolar bone loss increased with increasing age except for the 2 oldest age groups of current smokers. (arctichealth.org)
  • The mean alveolar bone difference was 5.5 per cent of the mean root length, which corresponds to an average bone loss of 0.09 mm per year. (arctichealth.org)
  • OBJECTIVES: I. Quantify periodontal alveolar bone loss rates in postmenopausal women. (clinicaltrials.gov)
  • To determine if adjuvant AI therapy use is associated with greater alveolar bone loss or increased levels of bone turnover biomarkers in postmenopausal women with cancer undergoing adjuvant AI therapy compared to postmenopausal women not receiving AI therapy. (clinicaltrials.gov)
  • BUFFALO, N.Y. -- A study conducted in a large sample of postmenopausal women by University at Buffalo epidemiologists has provided new information on the prevalence of certain gum-disease-causing oral bacteria in this population and the association of the bacteria with oral bone loss. (bio-medicine.org)
  • The study involved 1,256 postmenopausal women who were part of a larger population-based investigation of risk factors for osteoporosis and oral bone loss in postmenopausal women, which is an offshoot of the observational portion of the national Womens Health Initiative (WHI). (bio-medicine.org)
  • All respondents in 2012 reported required coursework on osteoporosis and alveolar bone loss in postmenopausal women. (adea.org)
  • Usually this empty socket will heal on its own, filling with bone and tissue. (thompsonoralsurgery.com)
  • Bone graft material is placed through a small incision in the gum tissue. (thompsonoralsurgery.com)
  • Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. (healthtap.com)
  • There must be enough alveolar bone support in all dimensions with sufficient attached keratinized tissue to allow for stabilization of the transplanted tooth. (omicsonline.org)
  • The periodontium is composed largely of the gingival tissue and the supporting bone. (wikipedia.org)
  • We have investigated the utility of a tissue-engineering approach to provide corrective therapies for tooth-bone loss. (mendeley.com)
  • These results demonstrate the utility of a hybrid tooth-bone tissue-engineering approach for the eventual clinical treatment of tooth loss accompanied by alveolar bone resorption. (mendeley.com)
  • Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. (curehunter.com)
  • Alveolar bone loss in osteoporosis: a loaded and cellular affair? (growkudos.com)
  • Epigenetic Mechanisms in Bone Biology and Osteoporosis: Can They Drive Therapeutic Choices? (mdpi.com)
  • Indeed, epigenetic factors, representing a link between individual genetic aspects and environmental influences, are also strongly suspected to be involved in bone biology and osteoporosis. (mdpi.com)
  • Exogenous and environmental stimuli, influencing the functionality of epigenetic mechanisms involved in the regulation of bone metabolism, may contribute to the development of osteoporosis and other bone disorders, in synergy with genetic determinants. (mdpi.com)
  • Oral bone loss is a major concern amongst a large population suffering from estrogen deficiency, osteoporosis and periodontal diseases. (suny.edu)
  • Using the information obtained from this pilot study, we believe, that applying these LIV on an osteoporotic animal model, using different combinations of mechanical loading can provide critical information on the potential treatment modality to prevent oral bone loss caused by diseases such as osteoporosis and periodontitis. (suny.edu)
  • Porphyromonas gingivalis ( Pg ) causes alveolar bone resorption, and morphologic measurements are the most frequent methods to identify bone resorption in periodontal studies. (hindawi.com)
  • Both groups revealed higher alveolar wall resorption on the buccal than on the lingual side at both time periods. (biomedsearch.com)
  • In healthy gums, the base of the pocket is coincident with the cemento-enamel junction (CEJ, the boundary between the enamel crown and the root) and there is no attachment loss. (springer.com)
  • Systemic administration of Morus nigra significantly inhibited the regional alveolar bone resorption and contributes to periodontal healing. (greenmedinfo.com)
  • Tooth height and mandibular bone quality were significantly decreased in sheep, exposed to very high levels of fluoride and low levels of calcium in drinking water. (fluoridealert.org)
  • Particularly, bone volume and cortical thickness of the mandibular bone were significantly reduced in these sheep. (fluoridealert.org)
  • In line with this finding, treatment with MCC950, a potent inhibitor of the NLRP3 inflammasome, significantly suppressed alveolar bone loss with reduced caspase-1 activation in aged mice but not in young mice. (elsevier.com)
  • In addition, our in vitro studies showed that the addition of IL-1β encourages RANKL-induced osteoclastogenesis from bone marrow-derived macrophages and that treatment with MCC950 significantly suppresses osteoclastic differentiation directly, irrelevant to the inhibition of IL-1β production. (elsevier.com)
  • They found that maxillary arches with incisor crowding and spacing had a significantly greater increase in periodontal pocket depth but not measured bone loss. (ada.org)
  • However, another study demonstrated that the alveolar bone height was significantly reduced in smokers compared to nonsmokers. (dentistryiq.com)
  • 4 Also, smoking has been shown to significantly increase the risk of tooth loss from periodontal disease. (dentistryiq.com)
  • 5 The effect appears to be dose-related, with heavy smokers exhibiting a significantly greater risk of tooth loss from periodontal disease compared to nonsmokers and lighter smokers. (dentistryiq.com)
  • It was also found that the extent of alveolar bone loss was significantly greater among subjects with ACS. (eurekalert.org)
  • Treatment with an anti-RANKL antibody as well as risedronate, a bisphosphonate, significantly inhibited the alveolar bone loss in OPG KO mice. (nii.ac.jp)
  • Maximum load of the molar alveolar region did not significantly change. (scielo.cl)
  • In the periodontium, ALP is very important enzyme as it is part of normal turnover of periodontal ligament, root cementum and maintenance, and bone homeostasis. (ispub.com)
  • The bone level, that is, the distance from the alveolar bone crest to cementumenamel junction (CEJ), was measured using 6.1 : 1 zoom stereomicroscope and software. (hindawi.com)
  • Lingual and buccal bone height, alveolar wall and total bone width 1, 3 and 5mm underneath the top of the crest were evaluated. (biomedsearch.com)
  • The effect of the distance from the contact point to the crest of bone on the presence or absence of the interproximal dental papilla. (thejcdp.com)
  • The progression of proximal alveolar bone loss (ABD index) in an unselected material comprising 406 individuals was analysed by a longitudinal investigation over a period of ten years. (arctichealth.org)
  • Morphometric registration of alveolar bone loss was carried out after 30 days of ligature placement to determine the effect of obesity on the progression of experimental peiodontitis. (ufrgs.br)
  • CONCLUSIONS Diabetes control, but not etiology, was associated with future tooth loss and accelerated AL progression. (diabetesjournals.org)
  • Eventually, this progression can cause tooth loss and systemic disease. (veterinarypartner.com)
  • Advanced Periodontitis Further progression of periodontitis with major loss of alveolar bone support usually accompanied by increased tooth mobility. (studystack.com)
  • All subjects had at least two interproximal sites with ≥3 mm clinical attachment loss. (nih.gov)
  • The Al exposure per si results in alveolar bone loss as well as potentiates damages of periodontitis induced cases. (bvsalud.org)
  • The cause of chronic inflammatory periodontitis, which leads to the destruction of periodontal ligament and alveolar bone, is multifactorial. (elsevier.com)
  • Fig. 1 ) and the resorption of the alveolar bone that occurs in parallel with the progressing attachment loss. (springer.com)
  • The base of the pocket is therefore apical to the CEJ, and attachment loss can be measured (in mm, using a periodontal probe) from the CEJ to the base of the pocket. (springer.com)
  • Examiners blinded to diabetes status performed random half-mouth periodontal examinations, assessing probing depth (PD) and attachment loss (AL) (four sites/tooth) at baseline and follow-up. (diabetesjournals.org)
  • Patients with aggressive periodontitis (AP) can undergo orthodontic treatment without added attachment loss, according to a study published in the April issue of American Journal of Orthodontics & Dentofacial Orthopedics. (ada.org)
  • Research has shown that smokers have more bone loss, attachment loss and tooth loss compared to non-smokers. (wikipedia.org)
  • The hallmark clinical feature of established periodontitis is attachment loss. (vin.com)
  • On oral exam, there are two different presentations of attachment loss. (vin.com)
  • The procedure also stimulates regeneration in the alveolar bone. (prweb.com)
  • This procedure helps recreate the natural contour of the gums and jaw that may have been lost due to bone loss from a tooth extraction, or for another reason. (thompsonoralsurgery.com)
  • In its mildest form, it can cause inflamed or bleeding gums, while in its severe form, it leads to bone loss, gum recession and even tooth loss. (medindia.net)
  • Alveolar bones of the left and right sides of the mandible were assessed by a morphometric method. (hindawi.com)
  • Morphometric analysis was used to evaluate alveolar bone loss. (biomedcentral.com)
  • Its anatomy is important for evaluating the morphometric symmetry of the mental triangle, microscopic and macroscopic morphology and maturity of the human mandible, bone remodeling activity and paleoanthropologic features of the facial skeleton in different populations. (ispub.com)
  • DR could be a supplementary medicine for periodontal therapy as it could reduce bone resorption in rat model of alveolar bone resorption and exert osteogenic effect on osteoblasts. (nih.gov)
  • When a tooth is removed an empty socket is left in the alveolar ridge bone. (thompsonoralsurgery.com)
  • Rebuilding the original height and width of the alveolar ridge may be required for dental implant placement or for aesthetic purposes. (thompsonoralsurgery.com)
  • Dental implants require bone to support their structure and a ridge augmentation can help rebuild this bone to accommodate the implant. (thompsonoralsurgery.com)
  • Time, usually 4-5 months, is allowed for the newly grafted bone to heal and become solid, fusing to your own alveolar ridge bone. (thompsonoralsurgery.com)
  • Not all patients are good candidates for ridge augmentation bone grafting. (thompsonoralsurgery.com)
  • Alveolar ridge preservation (ARP) has been shown to prevent postextraction bone loss. (hindawi.com)
  • Also, it was 16.16 mm below the alveolar ridge in males and 15.66 mm in females. (ispub.com)
  • You won't find an environmental cause for any bone cancer apart from the rare ones that arise in pre-existing severe Paget's of bone, rare genetic syndromes or an old radiation port. (healthtap.com)
  • The extent of bone loss was more severe in the ACS group than in the non-ACS group. (eurekalert.org)
  • We show that OPG KO but not RANKL-Tg mice exhibit severe alveolar bone destruction. (nii.ac.jp)
  • Results showed that women infected with four bacteria known to cause periodontal disease were more likely to have more severe oral bone loss than those without these oral pathogens. (bio-medicine.org)
  • Annual alveolar bone loss in older adults taking oral bisphosphonate: a retrospective cohort study. (harvard.edu)
  • Using an oral infection periodontitis model we demonstrate that following F. nucleatum infection no alveolar bone loss is observed in mice deficient for NCR1 expression, whereas around 20% bone loss is observed in wild type mice and in mice infected with P. gingivalis . (pubmedcentralcanada.ca)
  • Using mice deficient in NCR1 (the mouse orthlogue of NKp46), we demonstrate that oral infection of mice with F. nucleatum , but not with P. gingivalis results in an NCR1-dependent alveolar bone loss. (pubmedcentralcanada.ca)
  • The single-tooth restoration has become one of the most widely used procedures in implant dentistry.1 In the posterior region of the oral cavity, bone volume and density are often compromised. (zwp-online.info)
  • The clinical implication of oral bone loss is premature tooth loss. (suny.edu)
  • Participants in this study completed questionnaires, had physical measurements taken, had bone-density testing and an oral health examination. (bio-medicine.org)
  • Investigators used a measure called alveolar crestal height to determine the amount of oral bone loss. (bio-medicine.org)
  • In addition, cone-beam computed tomography was performed to evaluate the presence of periapical lesion and periodontal bone loss, and measure the distance from the root apex to the cortical of the maxillary sinus. (wellnessresources.com)
  • Alveolar Bone Loss" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • Changes in alveolar bone levels were clinically measured, and tissues were histopathologically examined to assess the differences among the study groups. (ovid.com)
  • Hybrid tooth-bone tissues were bioengineered as follows. (mendeley.com)
  • Histological and immunohistochemical analyses of the excised hybrid tooth-bone constructs revealed the presence of tooth tissues, including primary and reparative dentin and enamel in the tooth portion of hybrid tooth-bone implants, and osteocalcin and bone sialoprotein-positive bone in the bone portion of hybrid tooth-bone constructs. (mendeley.com)
  • it is a dental condition that damages the supporting structures of the tooth such as the soft tissues and the bone. (medindia.net)
  • Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE. (harvard.edu)
  • It is considered a highly suitable model to study bone remodeling activity and the maturity pattern of the human mandible.Its modal position varies according to age and race and has been cited ranging from sub canine to sub molar in different populations. (ispub.com)
  • However, neither ovariectomy nor naproxen has an effect on the molar alveolar region of the mandible. (scielo.cl)
  • or (4) triangular-shaped crowns associated with or without periodontal problems and alveolar bone resorptions. (thejcdp.com)
  • When periodontal disease is not treated, subgingival bacteria can continue to reproduce, potentially creating deeper periodontal pockets through bone destruction. (veterinarypartner.com)
  • Extra circumstances in which transplantation can be careful include tooth agenesis (particularly of premolars and lateral incisors), shocking tooth loss, atopic outbreak of canines, root resorption , large endodontic lesions, cervical root fractures , localized juvenile periodontitis as well as other pathologies. (omicsonline.org)
  • Prevalence of periodontitis and alveolar bone loss in a patient population at Harvard School of Dental Medicine. (harvard.edu)
  • The purpose of this research was to describe the prevalence of alveolar bone loss according to smoking status in Norway. (arctichealth.org)
  • The animals injected with saline or Escherichia coli-derived LPS into the maxillary alveolar mucosa on the buccoapical site of the molar region daily for 8 days were served as a negative or positive control, respectively. (unej.ac.id)
  • Owing to the loss of vertical bone volumes in the maxillary sinus area, an implantation with sufficient primary stability is often not possible. (zwp-online.info)
  • The enzyme ALP plays a role in bone metabolism. (ispub.com)
  • Also, bone metabolism has been demonstrated to be under the control of epigenetic mechanisms. (mdpi.com)
  • The progressive understanding of roles of epigenetic mechanisms in normal bone metabolism and in multifactorial bone disorders will be very helpful for a better comprehension of disease pathogenesis and translation of this information into clinical practice. (mdpi.com)
  • CLINICAL RELEVANCE: In the presence of high fluoride and low calcium-associated dental changes, deterioration of the mandibular bone and a potential alveolar bone loss needs to be considered regardless whether other signs of systemic skeletal fluorosis are observed or not. (fluoridealert.org)
  • The goal of the present study was to investigate the effects of ovariectomy and naproxen treatment on both femoral and mandibular bone mass and biomechanical competence. (scielo.cl)
  • Al may pose a major threat to humans , causing diseases and bone disorders. (bvsalud.org)
  • What diseases cause alveolar bone loss? (healthtap.com)
  • 2 The subjects who smoked were shown to be at greater risk for gingivitis, but no differences were noted in bone loss or increased periodontal pocketing. (dentistryiq.com)
  • Este documento revisa sistemáticamente la literatura disponible en bases de datos hasta Febrero de 2018 sobre la relación entre macronutrientes y el desarrollo y progresión de enfermedades periodontales (periodontitis y gingivitis) en animales, con particular atención a los posibles mecanismos implicados en estas patologías. (isciii.es)
  • New non-calcified bone-like matrix attached by osteoblasts at the root furcation was also shown. (nih.gov)
  • Bone implants were generated from osteoblasts induced from bone marrow progenitor cells obtained from the same pig, seeded onto PLGA fused wafer scaffolds, and grown for 10 days in a rotational oxygen-permeable bioreactor system. (mendeley.com)
  • Other bone lesions when enlarging such as dysplasias or giant cell tumors as preexisting lesions may result in malignant transformation. (healthtap.com)
  • What is the cause of lytic bone lesions and hypercalcemia? (healthtap.com)
  • Odontoclastic resorptive lesions involve the enamel cementum junction (ECJ, cervix) and root surface, leading to extensive loss of enamel, dentine and cementum. (wiley.com)
  • Together, Wnt5a regulates osteoclastogenesis and osteogenesis in alveolar bone remodeling. (nii.ac.jp)
  • abstract = "Periodontitis is a lesser known but frequent complication of diabetes mellitus and is the major cause of tooth loss in patients with diabetes. (nebraska.edu)
  • Bone mineral density (BMD) detection, osteoclast counting by tartrate resistant acid phosphatase staining, and histopathological analysis were performed in an induced rat model of alveolar bone resorption after gastric perfusion with DR extracts or Naringin. (nih.gov)
  • Axial osteosclerosis is a rare condition that causes increased bone density in areas like the pelvis, hip and spine. (healthtap.com)
  • Journal Article] Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone. (nii.ac.jp)
  • Ovariectomy decreased bone mineral density of the femoral midshaft, however naproxen prevented this decrease. (scielo.cl)
  • Analysis of roles of Wnt5a in alveolar bone remodeling, and their application for orthodontic tooth movement. (nii.ac.jp)
  • The articles included in the analysis were published in the English language and reported data on the use of implants with lengths below 10 mm in the posterior region with reduced alveolar bone height making the placement of longer implants impossible without additional surgical interventions. (medscimonit.com)
  • The tooth and bone implants were harvested, sutured together, reimplanted, and grown in the omenta for an additional 8 weeks. (mendeley.com)
  • 2002) 17 studied ALP in GCF from implants with and without periimplantitis and suggested that ALP could be a promising marker of bone loss around dental implants. (ispub.com)
  • The purpose of this study was to evaluate the use of short dental implants in distally reduced alveolar bone height. (medscimonit.com)
  • Alveolar bone loss using salivary and serum-derived bone markers. (clinicaltrials.gov)
  • Salivary ALP levels may be useful as a potential bone turnover marker to establish the diagnosis and prognosis of periodontal disease. (ispub.com)
  • Emanuel N, Machtei EE, Reichart M, Shapira L. D-PLEX500: a local biodegradable prolonged release doxycycline-formulated bone graft for the treatment for peri-implantitis. (harvard.edu)
  • Alveolar bone loss was measured according to standard methods by determining both the distance between the CEJ and the alveolar bone on the 2 molars between which the injections were made, and by measuring the ratio of root area/enamel area in the same region. (nebraska.edu)
  • Periodontitis is a common human chronic inflammatory disease that results in the destruction of the tooth attachment apparatus and tooth loss. (pubmedcentralcanada.ca)
  • 2003) 18 studied ALP activity in serum from patients with chronic periodontitis and showed a relationship between loss of attachment in periodontal disease and ALP activity in serum. (ispub.com)
  • If left untreated, progressive collagen and bone loss can weaken the tooth's anchoring in the alveolar housing and result in tooth loss. (diabetesjournals.org)
  • Assuming that alveolar bone loss is irreversible after smoking cessation, it could be hypothesized that there is a threshold period for tobacco smoking after which the accumulated effect of smoking becomes clinically observable. (arctichealth.org)
  • However, periodontal bone loss is irreversible (without regenerative surgery). (vin.com)
  • Increased IgE + B Cells in Sputum, but Not Blood, Bone Marrow, or Tonsils, after Inhaled Allergen Challenge in Subjects with Asthma. (nih.gov)
  • Bony mets can cause bony pain ( depending on the location), fractures, spinal cord compression resulting in significant nerve deficits on extremities/weakness/can develop paralysis etc, suppresion to the blood counts if cancer also involves the bone marrow etc. (healthtap.com)
  • What causes bone marrow tumors to form? (healthtap.com)
  • There are multiple different types of bone marrow tumors and the cause for almost all is unknown. (healthtap.com)
  • Neither ovariectomy nor naproxen treatment affected the BMD in the molar alveolar region. (scielo.cl)
  • Ninguna ovariectomía sin tratamiento de naproxeno afectó a la DMO en la región alveolar molar. (scielo.cl)
  • La carga máxima de la región alveolar molar no cambió en ninguna condición. (scielo.cl)
  • Sin embargo, ni la ovariectomía ni el naproxeno tienen un efecto en la región alveolar molar de la mandíbula. (scielo.cl)
  • It was found that the increase in mineralization was not caused by the changes in the chemical composition of the alveolar bone but perhaps attributed to the activation of osteocytes, which caused an increase in the mineralization. (suny.edu)
  • OPG was highly expressed in osteocytes in the alveolar bone, suggesting that OPG secreted from osteocytes prevents the alveolar bone loss induced by the excess amount of RANKL in RANKL-Tg mice. (nii.ac.jp)
  • A comparison between enamel matrix proteins used alone or in combination with bovine porous bone mineral in the treatment of intrabony periodontal defects in humans. (biomedsearch.com)
  • BACKGROUND: It has been shown that clinical improvement of intrabony periodontal defects can be achieved with the use of enamel matrix proteins (EMPs) or by grafting with bovine porous bone mineral (BPBM). (biomedsearch.com)
  • Intrabony defects were treated either with enamel matrix proteins (EMP group) or with enamel matrix proteins combined with bovine porous bone mineral (EMP/BPBM group). (biomedsearch.com)