Alveolar Bone Loss: Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.Alveolar Process: The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth.Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)Tooth Cervix: The constricted part of the tooth at the junction of the crown and root or roots. It is often referred to as the cementoenamel junction (CEJ), the line at which the cementum covering the root of a tooth and the enamel of the tooth meet. (Jablonski, Dictionary of Dentistry, 1992, p530, p433)Bacteroidaceae Infections: Infections with bacteria of the family BACTEROIDACEAE.Maxillary DiseasesBone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Bone Resorption: Bone loss due to osteoclastic activity.Porphyromonas gingivalis: A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.Periodontium: The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Periodontal Ligament: The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).Mandible: The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.Radiography, Bitewing: Technique involving the passage of X-rays through oral structures to create a film record while a central tab or wing of dental X-ray film is being held between upper and lower teeth.Photography, Dental: Photographic techniques used in ORTHODONTICS; DENTAL ESTHETICS; and patient education.Bone Remodeling: The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.Bone Density: The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.Tooth Socket: A hollow part of the alveolar process of the MAXILLA or MANDIBLE where each tooth fits and is attached via the periodontal ligament.Actinobacillus Infections: Infections with bacteria of the genus ACTINOBACILLUS.Aggregatibacter actinomycetemcomitans: A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.Periodontal Pocket: An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.Chronic Periodontitis: Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.Maxilla: One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.Macrophages, Alveolar: Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells.Alveoloplasty: Conservative contouring of the alveolar process, in preparation for immediate or future denture construction. (Dorland, 28th ed)Gingiva: Oral tissue surrounding and attached to TEETH.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.RANK Ligand: A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.Ligation: Application of a ligature to tie a vessel or strangulate a part.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Random Allocation: A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.Bone Regeneration: Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.Pulmonary Alveoli: Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.Tooth Movement: Orthodontic techniques used to correct the malposition of a single tooth.Osteonectin: Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.Tooth Eruption: The emergence of a tooth from within its follicle in the ALVEOLAR PROCESS of the MAXILLA or MANDIBLE into the ORAL CAVITY. (Boucher's Clinical Dental Terminology, 4th ed)Molar: The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821)Osteoclasts: A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.Dental Cementum: The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992)Bone Diseases, MetabolicBone Development: The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.X-Ray Microtomography: X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.Bone Matrix: Extracellular substance of bone tissue consisting of COLLAGEN fibers, ground substance, and inorganic crystalline minerals and salts.Bone Marrow: The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.Alveolar Bone Grafting: Surgical procedure to add bone to the ALVEOLAR RIDGE in children born with a CLEFT LIP and a CLEFT PALATE.Osteogenesis: The process of bone formation. Histogenesis of bone including ossification.Bone Transplantation: The grafting of bone from a donor site to a recipient site.Bone Diseases: Diseases of BONES.Bone Marrow Cells: Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.Tooth: One of a set of bone-like structures in the mouth used for biting and chewing.Tooth Extraction: The surgical removal of a tooth. (Dorland, 28th ed)Osteoblasts: Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.Radiography, Dental: Radiographic techniques used in dentistry.Tooth Root: The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)Periodontal Attachment Loss: Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.Mandibular DiseasesTooth Mobility: Horizontal and, to a lesser degree, axial movement of a tooth in response to normal forces, as in occlusion. It refers also to the movability of a tooth resulting from loss of all or a portion of its attachment and supportive apparatus, as seen in periodontitis, occlusal trauma, and periodontosis. (From Jablonski, Dictionary of Dentistry, 1992, p507 & Boucher's Clinical Dental Terminology, 4th ed, p313)Time Factors: Elements of limited time intervals, contributing to particular results or situations.Dental Implants: Biocompatible materials placed into (endosseous) or onto (subperiosteal) the jawbone to support a crown, bridge, or artificial tooth, or to stabilize a diseased tooth.Pulmonary Alveolar Proteinosis: A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.Femur: The longest and largest bone of the skeleton, it is situated between the hip and the knee.

Morphological changes in periodontal mechanoreceptors of mouse maxillary incisors after the experimental induction of anterior crossbite: a light and electron microscopic observation using immunohistochemistry for PGP 9.5. (1/419)

Ruffini nerve endings (mechanoreceptors) in the periodontal ligament (PDL) of mouse incisors were examined to elucidate whether experimentally-induced crossbites cause any changes or abnormalities in their morphology and distribution. Anterior guiding planes were attached to the mandibular incisors of 3-week-old C3H/HeSlc mice. At 3 days and 1, 2, 4, 6, and 8 weeks post-attachment of the appliance, the mice were sacrificed by perfusion fixation. Frozen sagittal cryostat sections of the decalcified maxillary incisors were processed for immunohistochemistry of protein gene product 9.5, followed by histochemical determination of tartrate-resistant acid phosphatase activity to reveal sites of alveolar bone resorption. Despite the absence of bone resorption within the lingual PDL of control mice, distinct resorption sites were seen in the respective regions of the experimental animals. Unlike the controls, many Ruffini endings showing vague and swollen contours, with unusually long and pedunculated micro-projections were observed in the affected lingual PDL of the incisors in the experimental animals with short-term anterior crossbite induction. Club-shaped nerve terminations with few, if any, micro-projections were observed in the lingual PDL of experimental animals with long-term induction, as well as in aged control mouse incisors. Differences in the distribution of Ruffini endings were also observed. These results indicate that changing the direction of the force applied to the PDL results in rapid and prolonged changes in the morphology of Ruffini-like mechanoreceptors.  (+info)

Histological and histochemical quantification of root resorption incident to the application of intrusive force to rat molars. (2/419)

This study was conducted to investigate the nature of root resorption resulting from intrusive forces applied to the rat lower molars, by means of histological and histochemical techniques with tartrate resistant acid phosphatase (TRAP). Thirty-eight 13-week-old Wistar strain male rats were used. Intrusive force was created by a fixed appliance which was adjusted to exert an initial force of 50 g for the duration of 1, 2, and 3 weeks. The degree of root resorption and distribution of TRAP positive cells were evaluated. On the root surface, the TRAP positive scores were low in the apical regions. Significant differences in the scores were found in the inter-radicular region of the roots between the experimental and control groups for the 2- and 3-week groups. More active resorption of bone occurred during the experimental period, as denoted by greater TRAP positive scores on the bone than on the root surface. Root resorption scores in the apical root region were larger in the 2- and 3-week groups than in the 1-week group. Significant differences in the root resorption scores were also found between the 1- and 3-week groups in the inter-radicular region, indicating that intrusive force application of a longer duration may lead to a higher frequency of root resorption. It is shown that, irrespective of the level of TRAP positive cells and root resorption scores, the degree of root resorption activity is higher in the apical root region than in the inter-radicular area. These results indicate that cellular cementum may be resorbed more easily because of its richer organic components and low mineralized structure.  (+info)

Host modulation as a therapeutic strategy in the treatment of periodontal disease. (3/419)

Specific microorganisms initiate the immunoinflammatory processes that destroy tissue in periodontitis. Recent work has demonstrated, in addition to bacterial control, that modulation of the host immunoinflammatory response is also capable of controlling periodontitis. Matrix metalloproteinases (MMPs) destroy collagen and other matrix components, and the osteoclastic bone remodeling determines the periodontal bone response to a bacterial challenge. Other components of the biology, including cytokines and prostanoids, regulate MMPs and bone remodeling and are also involved in regulating the production of defensive elements, such as antibody. Agents directed at blocking MMPs or osteoclastic activity are effective in reducing periodontitis. Agents that inhibit prostaglandin E2 and selective blockage of specific cytokines have also been effective. Improved knowledge of bacterium-host interactions and of the processes leading to tissue destruction will help to identify targets for host modulation to reduce periodontitis in selected situations.  (+info)

CD4(+) T cells and the proinflammatory cytokines gamma interferon and interleukin-6 contribute to alveolar bone loss in mice. (4/419)

In this study, we used a mouse model to examine the role of the adaptive immune response in alveolar bone loss induced by oral infection with the human gram-negative anaerobic bacterium Porphyromonas gingivalis. Severe combined immunodeficient mice, which lack B and T lymphocytes, exhibited considerably less bone loss than did immunocompetent mice after oral infection, suggesting that lymphocytes contribute to this process. Bone loss after oral infection was decreased in mice deficient in major histocompatibility complex (MHC) class II-responsive CD4(+) T cells, but no change in bone loss was observed in mice deficient in MHC class I-responsive CD8(+) T cells or NK1(+) T cells. Mice lacking the cytokine gamma interferon or interleukin-6 also demonstrated decreased bone loss. These results suggest that the adaptive immune response, and in particular CD4(+) T cells and the proinflammatory cytokines that they secrete, are important effectors of bone loss consequent to P. gingivalis oral infection. The studies also reinforce the utility of the mouse oral infection model in dissecting the pathobiology of periodontal disease.  (+info)

C-telopeptide pyridinoline cross-links. Sensitive indicators of periodontal tissue destruction. (5/419)

C-telopeptides and related pyridinoline cross-links of bone Type I collagen are sensitive markers of bone resorption in osteolytic diseases such as osteoporosis and osteoarthritis. We have studied the release of C-telopeptide pyridinoline crosslinks of Type I collagen as measures of bone destruction in periodontal disease. Studies in preclinical animal models and humans have demonstrated the relationship between radiographic bone loss and crevicular fluid C-telopeptide levels. We have recently found that C-telopeptide levels correlate strongly with microbial pathogens associated with periodontitis and around endosseous dental implants. Host-modulation of bone-related collagen breakdown has been shown by studies in humans demonstrating that MMP inhibition blocks tissue destruction and release of C-telopeptides in patients with active periodontal disease.  (+info)

Host responses to recombinant hemagglutinin B of Porphyromonas gingivalis in an experimental rat model. (6/419)

Porphyromonas gingivalis, a gram-negative, black-pigmented anaerobe, is among the microorganisms implicated in the etiology of adult periodontal disease. This bacterium possesses a number of factors, including hemagglutinins, of potential importance in virulence. Several hemagglutinin genes have been identified, cloned, and expressed in Escherichia coli. The purpose of this study was to characterize host responses to purified recombinant hemagglutinin B (rHag B), using the conventional Fischer rat as the experimental animal model. The effectiveness of immunization with rHag B on protection against experimental periodontal bone loss following infection with P. gingivalis was also evaluated. Groups of rats were immunized by the subcutaneous route with rHag B in complete Freund's adjuvant, immunized with rHag B and orally infected with P. gingivalis, nonimmunized and noninfected, or orally infected with P. gingivalis only. Serum and saliva samples were collected throughout the experiment and evaluated for serum immunoglobulin G (IgG) and IgM and salivary IgA antibody activity by enzyme-linked immunosorbent assay. No salivary IgA anti-Hag B activity was detected in the various groups of rats. A slight serum IgM response similar to that seen in preimmune samples was observed. Serum IgG antibody activity to Hag B was detected only in samples from rats immunized with rHag B. This response was primarily of the IgG1 and IgG2a subclasses, followed by IgG2b and low levels of IgG2c. Supernatants from rHag B-stimulated splenic lymphoid cell cultures from immunized rats contained high levels of gamma interferon, followed by interleukin-2 (IL-2), IL-10, and then IL-4. These results are consistent with the induction of T helper type 1 (Th1)- and Th2-like responses. Western blot analysis of sera derived from rHag B-immunized rats reacted with trichloroacetic acid (TCA) precipitates of P. gingivalis 33277, 381, A7A1-28, and W50, revealing a 50-kDa band reflective of Hag B. However, sera derived from rats immunized with P. gingivalis whole cells or from rats infected with P. gingivalis only did not react with rHag B but did react with TCA precipitates of P. gingivalis strains. Finally, radiographic measurements of periodontal bone loss indicated that rats immunized with rHag B had less bone loss than those infected with P. gingivalis only. These results demonstrate the effectiveness of purified rHag B in inducing a protective immune response and support the potential usefulness of this component of P. gingivalis in the development of a vaccine against adult periodontitis.  (+info)

Requirement of B7 costimulation for Th1-mediated inflammatory bone resorption in experimental periodontal disease. (7/419)

The CD28 costimulation at TCR signaling plays a pivotal role in the regulation of the T cell response. To elucidate the role of T cells in periodontal disease, a system of cell transfer with TCR/CD28-dependent Th1 or Th2 clones was developed in rats. Gingival injection of specific Ag, Actinobacillus actinomycetemcomitans 29-kDa outer membrane protein, and LPS could induce local bone resorption 10 days after the transfer of Ag-specific Th1 clone cells, but not after transfer of Th2 clone cells. Interestingly, the presence of LPS was required not only for the induction of bone resorption but also for Ag-specific IgG2a production. LPS injection elicited the induction of expression of both B7-1 and B7-2 expression on gingival macrophages, which otherwise expressed only MHC class II when animals were injected with Ag alone. The expression of B7 molecules was observed for up to 3 days, which corresponded to the duration of retention of T clone cells in gingival tissues. Either local or systemic administration of CTLA4Ig, a functional antagonist of CD28 binding to B7, could abrogate the bone resorption induced by Th1 clone cells combined with gingival challenge with both Ag and LPS. These results suggest that local Ag-specific activation of Th1-type T cells by B7 costimulation appeared to trigger inflammatory bone resorption, whereas inhibition of B7 expression by CTLA4Ig might be a therapeutic approach for intervention with inflammatory bone resorption.  (+info)

Long-term follow-up of maxillary incisors with severe apical root resorption. (8/419)

The purpose of the study was to analyse the mobility of teeth with severe orthodontically induced root resorption, at follow-up several years after active treatment, and to evaluate mobility in relation to root length and alveolar bone support. Seventy-three maxillary incisors were examined in 20 patients, 10-15 years after active treatment in 13 patients (age 24-32 years) and 5-10 years after active treatment in seven patients (age 20-25 years). All had worn fixed or removable retainers; seven still had bonded twistflex retainers. Total root length and intra-alveolar root length were measured on intra-oral radiographs. Tooth mobility was assessed clinically according to Miller's Index (0-4) and the Periotest method. Crestal alveolar bone level, periodontal pocket depth, gingival, and plaque indices, occlusal contacts during occlusion and function, and dental wear were recorded. There was a significant correlation (P < 0.05) between tooth mobility, and total root length and intra-alveolar root length. No correlation was found between tooth mobility and retention with twistflex retainers. None of the variables for assessment of periodontal status, occlusion and function were related to total root length or tooth mobility. It is concluded that there is a risk of tooth mobility in a maxillary incisor that undergoes severe root resorption during orthodontic treatment, if the remaining total root length is < or = 9 mm. The risk is less if the remaining root length is > 9 mm. Follow-up of teeth with severe orthodontically induced root resorption is indicated.  (+info)

*Periodontitis

... involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening ... Zadik Y, Bechor R, Shochat Z, Galor S; Bechor; Shochat; Galor (April 2008). "Ethnic origin and alveolar bone loss in Israeli ... of attachment loss Moderate: 3-4 mm (0.12-0.16 in) of attachment loss Severe: ≥ 5 mm (0.20 in) of attachment loss In the early ... periodontal surgery may be needed to stop progressive bone loss and regenerate lost bone where possible. Many surgical ...

*Periodontal pathology

Extension of the lesion into alveolar bone, periodontal ligament with significant bone loss Continued loss of collagen ... The disease consists of a chronic inflammation associated with loss of alveolar bone. Advanced disease features include pus and ... drifting and eventual loss Because bone loss makes its first appearance in the advanced lesion, it is equated with ... Features of the Established Lesion: Predominance of plasma cells without bone loss Presence of extravascular immunoglobulins in ...

*Periodontology

Untreated, these diseases lead to alveolar bone loss and tooth loss. As of 2017[update], these continue to be one of the ... The supporting tissues are known as the periodontium, which includes the gingiva (gums), alveolar bone, cementum, and the ... including the treatment of peri-implantitis which is inflammatory bone loss around dental implants. The etiology of peri- ... combined with host immuno-inflammatory mechanisms and other risk factors which lead to destruction of the supporting bone ...

*CMKLR1

"Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice". Journal of Bone and Mineral Research. doi: ... "A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone ...

*Body piercing

ISBN 81-89093-10-X. Liran, Levin (June 2007). "Alveolar Bone Loss and Gingival Recession Due to Lip and Tongue Piercing". N Y ... In some cases, the alveolar tooth-bearing bone is also involved, jeopardizing the stability and durability of the teeth in ... Bone, Angie; Fortune Ncube; Tom Nichols; Norman D Noah (21 June 2008). "Body Piercing in England: a Survey of Piercing at Sites ... It was popular among the Aztecs, the Mayans and the tribes of New Guinea, who adorned their pierced noses with bones and ...

*Healing of periapical lesions

This may further lead to furcal involvement through loss of clinical attachment and alveolar bone. A cursory clinical ... This is because neutrophils, which are rich sources of PGE2, are present when the majority of rapid bone loss occurs during the ... injured site and cause resorption of the periapical alveolar bone. It is possible that after conventional endodontic therapy ... Regeneration of the bone has been demonstrated to occur, on average, at a rate of 3.2 mm² per month, and studies suggest that ...

*Aggressive periodontitis

In advanced cases the alveolar bone loss may be depicted as a horizontal bone loss pattern radiographically. Mostly in ... Loss of attachment refers to the destruction of periodontium whereas the bone refers to the alveolar bone supporting the teeth ... "Five-year alveolar bone level changes in women of varying skeletal bone mineral density and bone trabeculation". Oral Surgery, ... to the alveolar bone crest is typically in the order of 1mm in young people. If the distance between the ACJ and alveolar bone ...

*Capnocytophaga

This condition increase alveolar bone loss, attachment loss, tooth mobility, and finally tooth loss (McGuire &Nunn, 1996). It ... involvement in bone infections: a review. Int J Antimicrob Agents. 2013 Jun;41(6):509-15. Rogers MB, Parker AC, Smith CJ. 1993 ...

*Marsh rice rat

Effect of dietary vitamin E supplement and rotational stress on alveolar bone loss in rice rats (subscription required). ... Effect of stannous fluoride and iodine on root caries and bone loss in rats. Ohio Journal of Science 88(3):99-100. Benson, D.E ... Vitamin E, fluoride, and iodide protect against bone loss associated with this disease in the rice rat and a high-sucrose diet ... The nasal and premaxillary bones extend back beyond the point where the lacrimal, frontal, and maxillary bones meet. In P. o. ...

*Porphyromonas gingivalis

Interproximal and horizontal alveolar bone loss in mouse models are seen in coinfections involving P. gingivalis and Treponema ... Vaccines made from P. gingivalis CPS apparently impair oral bone loss in murine models. These vaccines have been able to elicit ... In contrast, germ free mice inoculated with a P. gingivalis monoinfection incur no bone loss, indicating that P. gingivalis ... In these models, P. gingivalis inoculation causes significant bone loss, which is a significant characteristic of the disease. ...

*Edentulism

Loss of teeth alters the form of the alveolar bone in 91% of cases. In addition to this resorption of bone in the vertical and ... bone loss, presenting with a distal horizontal defect and a mesial vertical defect. Tooth #22 exhibits roughly 30% bone loss. ... The alveolar bone is unique in that it exists for the sake of the teeth that it retains; when the teeth are absent, the bone ... Bone loss with missing teeth, partials and complete dentures is progressive. According to Wolff's law, bone is stimulated, ...

*Dental abscess

If the tooth has pre-existing periodontal disease, with pockets and loss of alveolar bone height, it is more likely to be a ... The path of the infection is influenced by such things as the location of the infected tooth and the thickness of the bone, ... If left untreated, a severe tooth abscess may become large enough to perforate bone and extend into the soft tissue eventually ... In some cases, a tooth abscess may perforate bone and start draining into the surrounding tissues creating local facial ...

*Clinical attachment loss

They are also attached to the gingival (gum) tissue that covers the alveolar bone by an attachment apparatus; because this ... Teeth are attached to the surrounding and supporting alveolar bone by periodontal ligament (PDL) fibers; these fibers run from ... Although this is technically a loss of clinical attachment, the term clinical attachment loss is used almost exclusively to ... of the alveolar bone, it is termed the supracrestal attachment apparatus. The supracrestal attachment apparatus is composed of ...

*Periodontal probe

Depths greater than 3 mm can be associated with "attachment loss" of the tooth to the surrounding alveolar bone, which is a ...

*List of MeSH codes (C07)

... alveolar bone loss MeSH C07.465.714.204 --- furcation defects MeSH C07.465.714.258 --- gingival diseases MeSH C07.465.714.258. ... tooth loss MeSH C07.465.714.836 --- tooth migration MeSH C07.465.714.836.535 --- mesial movement of teeth MeSH C07.465.714.898 ... periodontal attachment loss MeSH C07.465.714.470 --- periodontal cyst MeSH C07.465.714.533 --- periodontitis MeSH C07.465. ...

*Periodontal charting

... the loss of periodontal fiber, the clinical attachment loss (CAL), alveolar bone loss, and help in assessing and determining a ...

*List of MeSH codes (C05)

... alveolar bone loss MeSH C05.116.264.579 --- osteolysis MeSH C05.116.264.579.052 --- acro-osteolysis MeSH C05.116.264.579. ... File "2006 MeSH Trees".) MeSH C05.116.070.265 --- bone cysts, aneurysmal MeSH C05.116.099.052 --- acro-osteolysis MeSH C05.116. ... fibrous dysplasia of bone MeSH C05.116.099.708.375.199 --- cherubism MeSH C05.116.099.708.375.372 --- fibrous dysplasia, ... bone demineralization, pathologic MeSH C05.116.198.247.400 --- decalcification, pathologic MeSH C05.116.198.371 --- ...

*Serial extraction

... periodontium and alveolar process) is preserved, therefore reduced alveolar bone loss Less retention period is indicated More ... Uprighting of incisors and early loss of posterior teeth may result in deep bite. A simple palatal bite plate may correct this ... basal bone discrepancy. Patients with straight profile and pleasing appearance. Class 2 and class 3 malocclusion with skeletal ... Absence of physiologic spacing Unilateral or bilateral premature loss of deciduous canines with midline shift Malpositioned or ...

*Crown lengthening

... chronic pain chronic inflammation of the gingiva unpredictable loss of alveolar bone In addition to crown lengthening to ... The alveolar bone surrounding one tooth will naturally surround an adjacent tooth, and removing bone for a crown lengthening ... it is often recommended to remove enough bone to have 3mm between the restorative margin and the crest of alveolar bone. When ... In other words, it is the height between the deepest point of the gingival sulcus and the alveolar bone crest. This distance is ...

*Debridement (dental)

A suprabony pocket occurs when there is horizontal bone loss, the bottom of the pocket is coronal to the alveolar bone. An ... infrabony pocket occurs when there is vertical bone loss where the bottom of the pocket is apical to the alveolar bone. ... pockets can cause the loosening and loss of dentition due to destruction of supporting tissues including the alveolar bone, PDL ... loss are considered pseudopockets.There are two types of periodontal pockets that are determined by the type of bone loss ...

*Platelet-rich fibrin

... a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. A ... PRF is used in guided bone and tissue regeneration PRF enhances alveolar bone augmentation and necrotic dental pulp and open ... "Platelet-Rich Fibrin Promotes Periodontal Regeneration and Enhances Alveolar Bone Augmentation". BioMed Research International ... platelet-rich fibrin (PRF) membrane containing bone growth enhancing elements can be stitched over the wound or a graft ...

*Bundle bone

... is a histologic term for the portion of the bone of the alveolar process that surrounds teeth and into which the ... Bundle bone is functionally dependent in that it resorbs following tooth extraction or loss. Araujo, M; Lindhe, J: The ... It can also be referred to as alveolar bone proper. ... Edentulous Alveolar Ridge. In Lindhe, J; Karring, T; Lang, NP; ...

*Socket preservation

... is a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. ... loss in bone volume in the six months after dental extraction. The jaw bone will never revert to its original shape once bone ... After extraction, jaw bone has to be preserved to keep the socket in its original shape. Without socket preservation, the bone ... Without socket preservation, residual bones could lose volume resulting in loss of facial vertical and horizontal dimension and ...

*Dental alveolus

... is a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. ... Alveolar bone is the bone that surrounds the roots of the teeth forming bone sockets. In mammals, tooth sockets are found in ... Polyphyodont Alveolar ridge Peck, Mogammad Thabit; Marnewick, Johan; Stephen, Lawrence (2011). "Alveolar Ridge Preservation ... Dental alveoli (singular alveolus) are sockets in the jaws in which the roots of teeth are held in the alveolar process with ...

*Bone destruction patterns in periodontal disease

... defects fenestrations dehiscenses Generalized bone loss occurs most frequently as horizontal bone loss. Horizontal bone loss ... known as alveolar bone, reduce in height in relation to the teeth, but the morphology of the remaining alveolar bone is altered ... Carranza, FA: Bone Loss and Patterns of Bone Destruction. In Newman, MG; Takei, HH; Carranza, FA; editors: Carranza's Clinical ... There are four chief types of bone defects that present in the alveolar bone: horizontal defects vertical, or angular, ...

*Deciduous teeth

... as well as surrounding alveolar bone by osteoclasts) and become absorbed by the forming permanent teeth. The process of ... Various cultures have customs relating to the loss of deciduous teeth. In English-speaking countries, the tooth fairy is a ... Also the muscles of the jaw and the formation of the jaw bones depend on the primary teeth to maintain proper spacing for ... The primary teeth maintain the arch length within the jaw, the bone and the permanent teeth replacements develop from the same ...
Objective: In this study we have assessed the renal and cardiac consequences of ligature-induced periodontitis in both normotensive and nitric oxide (NO)-deficient (L-NAME-treated) hypertensive rats.Materials and methods: Oral L-NAME (or water) treatment was started two weeks prior to induction of periodontitis. Rats were sacrificed 3, 7 or 14 days after ligature placement, and alveolar bone loss was evaluated radiographically. Thiobarbituric reactive species (TBARS; a lipid peroxidation index), protein nitrotyrosine (NT; a marker of protein nitration) and myeloperoxidase activity (MPO; a neutrophil marker) were determined in the heart and kidney.Results: In NO-deficient hypertensive rats, periodontitis-induced alveolar bone loss was significantly diminished. In addition, periodontitis-induced cardiac NT elevation was completely prevented by L-NAME treatment. on the other hand L-NAME treatment enhanced MPO production in both heart and kidneys of rats with periodontitis. No changes due to ...
Aim: The relationship between steroid sex hormones and periodontal disease has been extensively investigated in females; however, studies with males are still scarce. The aim of the present study was to analyze the influence of testosterone deficiency on alveolar bone loss and on the histological structure of the periodontal tissues of castrated rats with experimental periodontitis.. Materials and Methods: To test the hypothesis, we used 28 male Wistar rats obtained from the Unioestes Central Bioterium. When the animals reached 80 days of age, they were separated into four groups (N =7 animals/group): Control without ligature (CON), Control with ligature (CON+LIG), Castrated without ligature (CAST), and Castrated with ligature (CAST+LIG). At 90 days of age, the orchiectomy was performed in the appropriate groups. Sixty days after castration, the periodontal disease was induced by a ligation technique. At the end of the trials (90 days after castration), the animals were weighed and sacrificed ...
Verzeletti, Giliano Nicolini et al. Effect of obesity on alveolar bone loss in experimental periodontitis in Wistar rats. J. Appl. Oral Sci., Apr 2012, vol.20, no.2, p.218-221. ISSN 1678- ...
Koo GC, Blake JT, Shah K, Staruch MJ, Dumont F, Wunderler D, Sanchez M, McManus OB, Sirotina-Meisher A, Fisher P, Boltz RC, Goetz MA, Baker R, Bao J, Kayser F, Rupprecht KM, Parsons WH, Tong XC, Ita IE, Pivnichny J, Vincent S, Cunningham P, Hora D Jr, Feeney W, Kaczorowski G, Springer MS 1999 Correolide and derivatives are novel immunosuppressants blocking the lymphocyte Kv1.3 potassium channels. Cell Immunol 197:99-107 ...
Journal of Shahid Sadoughi University of Medical Sciences ماهنامه علمی پژوهشی دانشگاه علوم پزشکی و خدمات بهداشتی درمانی شهید صدوقی یزد
This might be one of several explanations as to why elevated bacteria and the combination of specific pathogens in periodontal pockets can be linked to a history of ACS," said Stefan Renvert, DDS, PhD and Department of Health Sciences, Kristianstad University. "We also found that the amount of periodontal bacteria results in an inflammatory response that elevates the white blood cell counts and high sensitivity C-reactive protein levels, which has also been linked in past studies to heart disease.". It was also found that the extent of alveolar bone loss was significantly greater among subjects with ACS. Seventy-seven percent of the participants in the ACS group and 42 percent in the control group demonstrated evidence of periodontitis. The extent of bone loss was more severe in the ACS group than in the non-ACS group.. Another reason people diagnosed with ACS may have higher oral bacteria could be due to their infectious susceptibility and lack of an adequate host inflammatory response, which ...
OBJECTIVE: The purpose of this study was to evaluate whether local administration of TIL could influence the expression of the inflammatory mediators IL-1β, TNF-α, MMP-8 and COX-2 in rats with experimental periodontitis (EP). METHODS: Twenty-four adult male rats (Rattus norvegicus, albinus, Wistar) were assigned to groups C, EP, EP-TIL (CControl group, EP-Periodontitis groups). On EP groups, a ligature was placed around maxillary 2nd molars on day 1. On group EP-TIL, 20 μL of TIL solution (1 mg/kg body weight) was injected into the subperiosteal palatal area adjacent to the maxillary 2nd molar every other day until euthanasia (day 11 ...
(2005) Young et al. Tissue Engineering. Tooth loss accompanied by alveolar bone resorption presents a significant clinical problem. We have investigated the utility of a tissue-engineering approach to provide corrective therapies for too...
Vitamins and minerals essential for improving the nutritional environment of periodontal bone and tissue.These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
PROTOCOL OUTLINE: This is a randomized, double-blind, placebo controlled study. Patients are randomly assigned to receive placebo or conjugated estrogens and, if no prior hysterectomy, medroxyprogesterone. Patients also receive calcium supplementation therapy daily for 3 years.. Participants in the placebo group may be removed from study if bone loss exceeds 5% per year.. A study duration of 3 years is anticipated. ...
Purpose: The aim of this study was to compare vertical and horizontal mandibular alveolar bone resorption by measuring bone morphological variation in Kennedy Class II removable partial denture (RPD) wearers and non-wearers using cone-beam computed tomography (CBCT).. Materials and Methods: In total, 124 sites in the CBCT scans of 62 (29 RPD non-wearers, 33 RPD wearers) Kennedy Class II patients were analyzed retrospectively. Three-dimensional representations of the mandible with superimposed cross-sectional slices were developed with the CBCT scans to evaluate the mandibular alveolar height and width by measuring distances between the mandibular canal, mylohyoid ridge, alveolar crest, and lower border of the mandible in four regions (eight sites) of Kennedy Class II non-wearers and wearers of RPDs.. Results: Mandibular alveolar bone height and width were significantly lower in edentulous sites when compared with dentate sites in both Kennedy Class II non-wearers and wearers of RPDs (p , 0.05). ...
In an article titled Periodontal Assessments of Postmenopausal Women Receiving Risedronate, a graduate of the Case Western Reserve University School of Dental Medicine, reports that drugs that are used to combat
Researchers at the University at Buffalo have been able to identify two key components in saliva that could be used to predict the amount of oral bone loss in future.
The treatment of intrabony defects is a real challenge in molar teeth as it is chronic, slowly progressing disease which needs timely intervention. Periodontal inflammation associated with intrabony defect is not a separate entity as it secondarily affects the pulp causing retrograde pulpitis. However, treatment of these lesions will be complicated due to extensive bone loss. The tooth was endodontically treated followed by periodontal surgery to eliminate the deep periodontal pocket and promote bone fill in osseous defect. PepGen P-15 composited with platelet rich plasma was utilized for enhancing bone formation. The combination of these graft materials provides synergistic effect on bone regeneration.
Researchers compared the effect of a daily atorvastatin 80 mg dose versus a 10 mg dose in a randomized, multi-center trial with 71 subjects with established atherosclerosis or risk factors for atherosclerosis. Patients were evaluated using F-Flurodexoyglucose positron emission tomography (FDG-PET) imaging. After 12 weeks, there was a significant reduction in periodontal inflammation in subjects randomized to the 80 mg dose (p=0.04). Reductions in periodontal inflammation were greatest in individuals with higher levels of periodontal inflammation at baseline (p=0.01) and in those with higher periodontal bone loss at baseline (p=0.03). The reductions in periodontal inflammation correlated with reductions in carotid inflammation (p,0.001). "The impact of high-dose statin was greatest in individuals with evidence of active periodontitis and was evident after a four-week treatment period," said lead author Sharath Subramanian, MD, Massachusetts General Hospital and Harvard Medical School, Boston. "We ...
Differing theories of the nature of periodontal disease progression have been proposed, but there is no convincing statistical evidence with which to choose between them. Three models for disease progression are developed, and their covariance structures are derived and shown to be hierarchical. The estimation of the covariance structures of...
Results: No significant differences were found between both groups in survival, complications, or marginal bone resorption. One axially placed implant was lost at 58 months in group 1, rendering a cumulative survival estimate at 5 years of 96.7% and 98.3% in group 1 and the total sample, respectively (P = .317). Mechanical complications occurred in 16 patients (26.7%; n = 8 patients in each group; [P > .999]), consisting of fractures in the provisional prosthesis (n = 8 patients), chipped ceramics of the definitive prosthesis (n = 2 patients), loosening of prosthetic components (n = 5 patients), and fracture of an attachment screw (n = 1 patient). Biologic complications occurred in 5 patients (8.3%; group 1 = 4 patients; group 2 = 1 patient; [P = .161]), consisting of peri-implant pathology. The mean ± SD marginal bone loss was 2.02 ± 0.36 mm and 1.90 ± 0.69 mm for groups 1 and 2, respectively (P = .235). In group 1, the mean ± SD marginal bone loss was 1.92 ± 0.48 mm and 2.11 ± 0.44 mm ...
Parathyroid hormone is an endogenous hormone with potent anabolic and catabolic actions in bone. It has recently been approved for the treatment of osteoporosis and is marketed as FORTEO by Eli Lilly and Company. Numerous studies in humans have validated its use to increase bone mineral density and prevent fractures. Interest has also surfaced in its potential application in the treatment of non-osteoporotic fractures and several animal studies have supported this local application. Little is known regarding its use in treating conditions of the oral cavity, but animal studies suggest that bones of the oral cavity are responsive to the anabolic actions of PTH. Furthermore, a recent study indicated that in a canine model, PTH was effective at reversing periodontal bone loss. Studies from our laboratory indicate that patients with hyperparathyroidism (HPT) do not have an increase in periodontal disease as measured by attachment levels. In fact, in our patient population there was an increase in ...
The main finding is that the enhanced alveolar bone loss associated to age may be targeted by an appropriate dietary treatment. Our method uses biological knowledge expressed by Gene Ontology and generates a rule model associating this knowledge with minimal characteristic features of temporal gene expression profiles. The relatively low attack rate and also relative risk requires large sample sizes for free cialis generic testing hypotheses. From genes to function: the next challenge to understanding multiple sclerosis.. Recommendations for early diagnosis and intervention in autism spectrum disorders: an Italian-Israeli consensus conference. The purpose of this article is to reexamine some of the principles of correction. 6-Shogaol was shown to damage microtubules and discount generic cialis induce mitotic arrest. There was a weak association between adduct levels and daily cigarette consumption above 10 cigarettes per day. The results indicate that the PFD could be a useful tool for ...
The Straumann® Bone Level Tapered (BLT) Implant offers all the clinically proven features of the Straumann® Bone Level Implant line plus the advantages of a tapered implant body. This leads to excellent primary stability in soft bone and fresh extraction sockets. The tapered form adequately compresses the underprepared osteotomy. It also lets you effectively master your patients limited anatomy, such as facial undercuts, converging root tips, a concave jaw structure or narrow atrophied ridges ...
The Straumann® Bone Level Tapered (BLT) Implant offers all the clinically proven features of the Straumann® Bone Level Implant line plus the advantages of a tapered implant body. This leads to excellent primary stability in soft bone and fresh extraction sockets. The tapered form adequately compresses the underprepared osteotomy. It also lets you effectively master your patients limited anatomy, such as facial undercuts, converging root tips, a concave jaw structure or narrow atrophied ridges ...
Current therapeutics such as bisphosphonates or anabolic agents do not always effectively prevent or treat osteoporosis and inflammatory bone loss in rheumatoid...
I am new to the forum and tomorrow I am going in for the beginning of having dental implants due to bone loss! I have been so confused as to why I have had bone loss. I had PE with all 3 of my children and HELLP with my second. My youngest is 8 years old and I am approaching 49. My Mother had PE her first pregnancy and had dental bone loss issues. Back in the 1970s they told her here bone loss was due to her pregnancies. I am glad I decided to search for this. It gives me something to think about ...
31 years-old male patient was loss of anterior teeth for 1 year. . We have treated this case using Geistlich Bio-Oss® and Geistlich Bio-Gide® guide bone regeneration. After 6 months, the post-examination showed that that site had well-developed alveolar bone. After 1 year, permanent restoration was performed.. ...
Bone loss is a problem that not only plagues the elderly, but the younger generation as well. This condition does not form overnight. Nobody can say that with just a ...
Objective The prevalence of periodontitis is increased in patients with rheumatoid arthritis (RA), and the severity of periodontitis can affect the level of arthritis. Porphyromonas gingivalis is one of the main bacteria involved in periodontitis. Our aim was to determine if there are differences in the innate immune response against ... read more P gingivalis between healthy controls and RA patients. Methods Monocyte-derived dendritic cells (DCs) from healthy controls, RA patients, and patients with psoriatic arthritis (PsA) were stimulated with P gingivalis, a range of other bacteria, and Toll-like receptor agonists. Cytokine production was determined, and blocking studies were performed to determine which receptors were involved in differential recognition of P gingivalis. Effects on T cell cytokines were also determined in cultures of peripheral blood mononuclear cells (PBMCs). Results Upon stimulation with P gingivalis, RA patient DCs produced less tumor necrosis factor as compared to ...
Clinicians very often have seen marginal bone loss around dental implants at the crest level early on after implant placement and uncovering. Early clinical publications had suggested that this bone loss occurred during the first year of loading. Thus, numerous attempts have been made to minimize or eliminate such bone loss. However, the timing and reason for this bone loss are not always apparent. The objective of this study was to review the evidence regarding marginal bone loss around dental implants from the standpoint of biologic consequences to help understand marginal bone changes around dental implants. One hypothesis for the bone loss around these implants was related to the presence of bacteria in the interfaces between the implant and abutment connections. The literature was reviewed regarding the three major types of implant-abutment crestal connections, including butt-joint, platform-switched, and no interface (tissue-level or one-body). This review article revealed that 1.5 to 2.0 ...
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A range of regenerative treatments have been used for the treatment of periodontal infrabony defects. Guided tissue regeneration (GTR) and enamel matrix derivatives (EMD) are two popular treatment and they have both been used in combination with other treatment. This network meta-analysis was conducted to assess the potential effects of the various combinations. Unlike a [read the full story…]. ...
The suitability of a mouse model for host response in the induction of alveolar bone loss by Porphyromonas gingivalis was explored. The mouths of immunocompetent and severe combined immunodeficient (SCID) mice were infected with P. gingivalis ATCC 53977. P. gingivalis was not isolated from the mouths of these mice before infection, but was present at least 42 days after infection. P. gingivalis-specific IgG was present in sera from the infected, immunocompetent mice at the end of these experiments (42 days). Specific IgG was not present in sham-infected or uninfected immunocompetent mice, nor in any immunodeficient mice. Specific IgM was not present in any sera at 42 days. Infected, immunocompetent mice of two strains showed significant bone loss in comparison to sham-infected or uninfected immunocompetent mice (p | 0.05). Infected SCID mice, which are genetically lacking both B and T lymphocytes, also showed significant bone loss compared with sham-infected or uninfected SCID mice (p | 0.05
Abstract. Background: Chronic periodontitis is an inflammatory disease that affects the supporting tissues of the teeth and its common among adults. Smoking is an important risk factor for periodontitis induces alveolar bone loss. Alkaline phosphatase enzyme is involved in the destruction of the human periodontium. It is produced by many cells such as polymorphonuclear leukocytes, osteoblasts, macrophages and fibroblasts within the area of the periodontium and gingival crevice. Osteocalcin is one of the most abundant matrix proteins found in bones and the only matrix protein synthesized exclusively there. Smaller Osteocalcin fragments are found in areas of bone remodeling and are actually degradation products of the bone matrix.The purpose of this study was to evaluatethe effect of smoking on the salivary alkaline phosphatase and Osteocalcin in subjects with chronic periodontitis compared to control subjects. Materials and Methods: Five ml of unstimulated whole saliva samples and full-mouth ...
Parathyroid hormone (PTH) functions as a major mediator of bone remodeling and as an essential regulator of calcium homeostasis. In addition to the well-established catabolic effects (activation of bone resorption) of PTH, it is now recognized that intermittent PTH administration has anabolic effects (promotion of bone formation). The aim of this study was to investigate whether intermittent administration of PTH in rodents would block the alveolar bone loss observed in rats when a ligature model of periodontitis is used. Morphometric analysis showed that intermittent PTH administration (40 microg/kg) was able to protect the tooth site from periodontitis-induced bone resorption. In addition, there was a significant reduction in the number of inflammatory cells at the marginal gingival area in sections obtained from animals receiving PTH compared with control animals. These findings demonstrated that intermittent PTH administration was able to protect against periodontitis-associated bone loss in ...
Stress distribution in the mini-screw and alveolar bone during orthodontic treatment : a finite element study analysisStress distribution in the mini-screw and alveolar bone during orthodontic treatment : a finite element study analysisAN0009999X ...
The soft and hard tissues that surround an implant can be easily exposed to infection. A natural tooth has and is prepared for a certain level of mobility. When its exposed to extreme forces, the tooth is allowed to move a little, as the dental ligaments take upon them an important percentage of those forces. The dental implant is not sustained by dental ligaments and thats why all the pressure that is put on them is transmitted directly to the surrounding tissues. Those forces damage the hard and soft surrounding tissues and lead to infections, gum recession and alveolar bone resorption.. There are three types of peri-implantitis, which can all be treated in our dental clinics using minimally invasive techniques (tisular regeneration - Electronic Doctor , occlusal adjustment):. ...
Non-healing bone fractures and periodontal bone loss constitute significant clinical problems with few approved medical options. Bone repair is enhanced by the presence of osteoblasts or osteoblastic precursor cells. Subcutaneous adipose tissue is a plentiful, accessible, and replenishable source of human stromal cells for transplantation. In Phase I of this SBIR, we tested the hypothesis that human adipose tissue-derived stromal cells are capable of osteoblast function. Substantial in vitro data indicates that these stromal cells differentiate into cells biochemically and morphologically similar to osteoblasts. The ability of these cells to form bone in vivo was examined as well. Phase II of this SBIR will extend these in vivo experiments. Specific Aim 1 examines the ability of human adipose tissue-derived stromal cells to form ectopic bone in hydroxyapatite ceramic cubes implanted subcutaneously in immunodeficient mice. Specific Aim 2 explores whether the introduction of a modified bone ...
If you have been in practice long enough, you will have run into something like this eventually. This is a 76 year old farmer who has fairly obviously been "grinding his teeth". In fact, you would be making a correct assumption. Note that the tooth wear is much worse anteriorly than it is in the posterior. As we will eventually see, this is diagnostic of abrasion from bruxism. But notice a few other less obvious things. You see no occlusal amalgam fillings in the posterior teeth. You see no plaque or redness around the gingiva. You see no active decay anywhere. Furthermore, the patient has no periodontal bone loss in spite of a serious bruxing habit. On the other hand, you do see a few buccal composite fillings along with severe buccal-cervical wear. We can conclude the following from these observations:. This patient has probably never used too much sugar. We conclude this by the lack of amalgam fillings in the intact molars and the occlusal of #4, the one "surviving" premolar.. The patient has ...
The bottom teeth are used more for the grinding of food and the top front teeth are mainly used for biting. Dental anatomy is a field of anatomy dedicated to the study of tooth structures. The development, appearance, and classification of teeth fall within its field of study, though dental occlusion, or contact among teeth, does not. Dental anatomy is also a taxonomical science as it is concerned with the naming of teeth and their structures. This information serves a practical purpose for dentists, enabling them to easily identify teeth and structures during treatment. The anatomic crown of a tooth is the area covered in enamel above the cementoenamel junction (CEJ).[3] The majority of the crown is composed of dentin with the pulp chamber in the center.[4] The crown is within bone before eruption.[5] After eruption, it is almost always visible. The anatomic root is found below the cementoenamel junction and is covered with cementum. As with the crown, dentin composes most of the root, which ...
Our understanding about periodontal disease progression improved tremendously during 1960s, when animal and human experiments demonstrated the role of bacteria in the initiation of gingivitis and periodontitis 1, 2. These studies led to the proposal of the model of bacterial etiology of periodontal disease. Further investigations in this field led to the advancement of our knowledge of pathogenic bacteria causing disease progression. Specific Gram-negative, anaerobic, or microaerophilic bacteria were implicated in the causation of periodontitis 3-7. During late 1970s and early 1980s protective and destructive roles of the immunoinflammatory responses were described in health and disease 8-14.. Most of the models of periodontal disease progression in the late 1980s stated that specific bacteria initiated the disease process by activating host responses, which were protective and destructive. The actual destruction of connective tissue and bone resulted primarily from inflammatory chemical ...
Evaluation of the Effect of Buccolingual and Apicocoronal Positions of Dental Implants on Stress and Strain in Alveolar Bone by Finite Element Analysis
Calcium aids in development of strong bones and teeth. It also helps your heart, nerves, and muscles. Calcium deficiency often doesnt show symptoms right away, but leads to serious health problems over time. If calcium consumption isnt enough, your body may use the calcium from your bones instead, leading to bone loss.. Experts also believe that calcium deficiencies may be related to low bone mass and weakening of bones due to osteoporosis.. Calcium deficiency leads to convulsions and abnormal heart rhythm which can be life-threatening. Postmenopausal women experience greater bone loss due to changing hormones experiencing troubles absorbing calcium.The best sources of calcium are dairy products such as milk, yogurt, cheese, calcium-set tofu, and small fish with bones. Vegetables such as kale and broccoli also have calcium, and many cereals and grains are calcium-fortified.. ...
Ferreira CEA, Novaes AB Jr, Haraszthy VI, Bittencourt M, Martinelli CB, Luczyszyn SM. A clinical study of 406 sinus augmentations with 100% anorganic bovine bone. J Periodontol 2009;80(12):1920-1927.. Sinus grafting with anorganic bovine bone was performed in 222 patients requiring unilateral sinus grafting and 92 patients requiring bilateral sinus grafting; a total of 1,025 implants were placed (118 simultaneous with grafting and 907 at second stage surgery after 6-12 months). After 3 years, the implant survival rate was 98.1% (19 implants were lost), with no significant differences in survival between implants with rough or machined surfaces, or between implants placed in various heights of native bone. Histomorphometry showed 39.0 ± 12% new bone formation and 52.9% ± 9.3% marrow space.. Song D-W, Lee D-W, Kim C-K, Park K-H, Moon I-S. Comparative analysis of peri-implant marginal bone loss based on microthread location: a 1-year prospective study after loading. J Periodontol ...
Results: One patient (11-mm group) died before the 12-month evaluation and one patient (6-mm group) moved away. In addition, one patient in the 6-mm group lost one implant and no implants were lost in the 11-mm group. Two patients lost three restorations in the 6-mm group and no restorations were lost in the 11-mm group. From loading until the 60-month assessment, the mean marginal bone loss in the 6-mm group and the 11-mm group was 0.12 ± 0.36 mm and 0.14 ± 0.63 mm, respectively, without a significant difference (mean difference 0.02 mm; 95% CI -0.32 to 0.37; P = 0.884). Implant loss, restoration loss, screw loosening and porcelain chipping were defined as complications. Four patients in the 6-mm group and one patient in the 11-mm group had one or more complications, without a significant difference between the groups (95% CI 0.019 to 0.244; P = 0.198). The patient satisfaction was high in both groups (mean overall satisfaction in the 6-mm and the 11-mm groups was 9.4 ± 0.8 and 9.2 ± 0.8, ...
Cimetidine is a powerful H2 receptor antagonist originally designed to treat ulcers by blocking the acid producing cells in the stomach. In the study three groups of rabbits were simultaneously induced with experimental periodontitis using P. gingivalis and treated with varying levels of topically applied cimetidine three times a week over a six-week period. Results showed that topical application of cimetidine at all concentrations inhibited inflammation and bone loss by approximately 90 ...
... to reshape remove pockets in the alveolar bone surrounding the teeth, Highland Park Periodontics & Dental Implants Dallas TX. 214-559-4670
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This study aimed to investigate the effect of experimental periodontitis on rat penis. Eighteen Wistar rats underwent the placement of a cotton ligature around the first molars to induce periodontitis. It was confirmed that periodontitis was induced in the group with ligature due to the greater number of osteoclasts, decreased osteocytes, greater distance from the cementoenamel junction to the alveolar crest, increase in gingival swelling (p |0.05) and intense bone resorption. Furthermore, there was a higher average concentration of IL-6 in the gingival samples and of TNFα in the penile samples of the rats with ligature (p |0.05). There was a statistically significant thicker and smaller area of the dorsal penile arteries in the experimental group, as well as a smaller area of the vascular spaces of the corpora cavernosa (p|0.05). Therefore, the systemic inflammation caused by periodontal disease can be an important risk factor for erectile dysfunction.
Periodontitis is a chronic inflammatory disease caused by exaggerated host immune responses to dysregulated microbiota in dental biofilms leading to degradation of tissues and alveolar bone loss. Porphyromonas gingivalis is a major periodontal pathogen and expresses several potent virulence factors. Among these factors, arginine and lysine gingipains are of special importance, both for the bacterial survival/proliferation and the pathological outcome. The major aim of this thesis was to develop and test novel methods for diagnosis and prevention of P. gingivalis infection and periodontitis. In study I, anti-P. gingivalis antibodies were developed in vitro for immunodetection of bacteria in clinical samples using a surface plasmon resonance (SPR)-based biosensor. Specific binding of the antibodies to P. gingivalis was demonstrated in samples of patients with periodontitis and the results were validated using real-time PCR and DNA-DNA checkerboard analysis. In study II, we elucidated the ...
in European Journal of Oral Implantology (2015), 8(3), 233-244. PURPOSE: To evaluate the effectiveness of a bone substitute covered with a resorbable membrane versus open flap debridement for the treatment of periodontal infrabony defects. MATERIALS AND METHODS ... [more ▼]. PURPOSE: To evaluate the effectiveness of a bone substitute covered with a resorbable membrane versus open flap debridement for the treatment of periodontal infrabony defects. MATERIALS AND METHODS: Ninety-seven patients with one infrabony defect, which was 3 mm or deeper and at least 2 mm wide were randomly allocated either to grafting with a bone substitute covered with a resorbable barrier (BG group) or open flap debridement (OFD group) according to a parallel group design in five European centres. Blinded outcome measures assessed tooth loss, complications, patients satisfaction with treatment and aesthetics, changes in probing attachment levels (PAL), probing pocket depths (PPD), gingival recessions (REC), ...
DOI: 10.11607/prd.00.0342 The aim of the present study was to evaluate clinically and histologically the treatment of intrabony periodontal defects with a bioresorbable membrane barrier. Fifty-two intrabony periodontal defects were treated according to the principles of guided tissue regeneration (GTR) with a bioresorbable membrane. Results were evaluated by assessing probing pocket depth, recession of the gingival margin, and clinical attachment level at baseline and at 1 and 2 years after therapy. Bone level changes were evaluated radiographically. The postoperative phase was uneventful in all cases. There was a mean probing pocket depth reduction from 8.4 to 3.6 mm, a mean increase of gingival margin recession from 1.5 to 3.0 mm, and a mean clinical attachment level change from 9.9 to 6.5 mm. Mean attachment gain was 3.4 mm. Two teeth scheduled for extraction were also treated with the same bioresorbable membrane. The histologic analysis 6 months after treatment revealed the formation of new ...
Chronic periodontitis is strongly associated with composition of the oral biofilm occupying the gingival crevicular aspect of the tooth and its associated root. Some gram-negative, red complex bacteria instigate periodontal bone loss in patients, principal among these Porphyromonas gingivalis. P. gingivalis is a late colonizer, indicating not only its physical location within the oral biofilm, but also the pathogenic dynamic of the interaction between P. gingivalis and the host innate immunity. Among several other subversive tactics, P. gingivalis has been shown to compel receptors vital to the orchestration of an appropriate immune response to co-associate and consequently signal in a way that directly benefits the pathogen. Upon interaction with human monocytes and murine macrophages, P. gingivalis has been shown to induce TLR2 and CXCR4 to co- associate in lipid rafts via its surface fimbriae. The ensuing crosstalk results in a cAMP dependent, PKA mediated inhibition of NF-KB which in turn leads
Periodontitis is a condition that may be controlled but not cured. It is often seen in pets that are over five years old. Most animals with periodontitis have bad breath, tooth mobility and bleeding gums. Severe inflammation of the gums, gum recession, alveolar bone loss (the bone that supports the tooth is "eaten away"), and pustular discharge are common signs of periodontitis.. ...
Department of Periodontology/Community and Preventive Dentistry, College of Health Sciences, University of Nairobi, P.O. Box 19676-00202, Nairobi, Kenya. OBJECTIVE: To map out the pattern of periodontal disease in individuals who died before 1957 and were not exposed to formal dental services. DESIGN: Descriptive cross-sectional study. SETTING: National Museums of Kenya. SUBJECTS: The skeletons of people who died before independence are preserved at the National Museums of Kenya in Nairobi. Sixty four out of the 170 dry mandibles stored at the Museum were assessed for periodontal bone loss using a calibrated ruler. RESULTS: All the 64 mandibles assessed were of individuals who died before 1957. Two thousand two hundred and seventy four sites were examined. Most of the subjects were adults aged 30-45 years and the age range was 18-80 years. Majority of the mandibles examined were of the ethnic group from Central Kenya. Of the teeth examined, premolars and molars were the teeth most frequently ...
Figure 3: Effect of PRF, PPP, and DMEM media on mineralization behavior of periodontal progenitor populations. (a), (c), (e), and (g) are alkaline phosphatase staining assays and (b), (d), (f), and (h) are alizarin red S mineralization assays. In (a)-(f), alkaline phosphatase ((a), (c), and (e)) or alizarin red ((b), (d), and (f)) staining in periodontal progenitor cells cultured for 7, 14, and 21 days were compared. Different coculture conditions (PRF, PPP, OM, and DMEM) are distinguished by different bar patterns which are identified in the bar legend above (b). The three periodontal progenitor populations compared in this study, dental follicle (DF), periodontal ligament (PDL), and alveolar bone (AB) are labeled on the ...
In my experience, only two implant systems excel at preserving crestal bone. Astra and Ankylos implants are the only two that I have seen published and personal results with preserved marginal bone. This week I delve into several excellent articles and break down the data on marginal bone loss. I currently place mostly Nobel implants followed by Astra implants. One article shows that after the one year mark the bone loss for an Astra implant was the same as a Branemark implant but the key is that this was after close to 1.75mm of bone loss with the Branemark vs the 0.4mm of bone loss with the Astra implant. ...
BACKGROUND: Implants replacing missing teeth provide advantages over clinical orthodontic treatment as compensation for reaction forces is no longer necessary and the lack of teeth is immediately resolved. METHODS: A total of 38 two-stage implants were inserted (16 in maxilla, 22 in mandible) in 10 partially edentulous patients with orthodontic problems. Osseointegration and marginal bone levels were assessed via intra-oral radiographs taken at the abutment stage and at the completion of the orthodontic treatment and also via probing depth, measurement of recession toward the implant/abutment (I/A) interface, and sulcus bleeding index, recorded after completion of orthodontic treatment. RESULTS: In the maxilla, the cumulative survival rate was 87.1% after 2 years; for the mandible, it remained 100%. Mean amount of bone loss was 1.6 mm for maxilla and 0.8 mm for mandible. No correlation could be found between directions of orthodontic forces and marginal bone loss. Mean percentage of bleeding ...
Association of total protein intake with bone mineral density and bone loss in men and women from the Framingham Offspring Study - Public Health Nutr. 2013 Oct 29:1-7 - This suggests that greater protein intake benefits women especially those with lower Ca intakes. However, protein effects are not significant for short-term changes in bone density. Contrastingly, in men, higher protein intakes lead to greater bone loss at the trochanter. Dietary Intake of Vegetables, Fruits, and Meats/Beans as Potential Risk Factors of Acute Myeloid Leukemia: A Texas Case-Control Study - Nutr Cancer. 2013 Oct 29 - This study was conducted at the University of Texas MD Anderson Cancer Center to evaluate associations between consumption of vegetables, fruits, and meats with AML risk among Texas residents ... Overall, AML risk was significantly decreased among those who consumed the most dark green vegetables, seafood, and nuts/seeds; and it was significantly increased among greatest consumers of red meat. Among ...
TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents ...
Kondo T, Hotokezaka H, Hamanaka R, Hashimoto M, Nakano-Tajima T, Arita K, Kurohama T, Ino A, Tominaga JY, Yoshida N.:Types of tooth movement, bodily or tipping, do not affect the displacement of the tooths center of resistance but do affect the alveolar bone resorption.¸Angle Orthodontist¸doi: 10.2319/110416-794.1..¸2017/02 ...
Periodontal disease, a common inflammatory oral disease involved periodontal tissues, has been linked with the evidence of some systemic disorders. Recently, periodontal disease has been suspected ...
ONLINE COVER A Healthy Smile (or Snarl). Periodontitis is chronic inflammation of the tissues surrounding teeth, and is not only the primary cause of tooth loss in adults, but also raises the likelihood of heart disease. Shin and colleagues discovered that an anti-inflammatory protein natural to the human body, called DEL-1, also works to prevent bone loss by acting directly on osteoclasts-the cells that resorb bone. Giving DEL-1 to mice and cynomolgus monkeys (on cover) with periodontitis stopped inflammation, restored healthy tissues, and prevented bone loss, suggesting that this endogenous protein holds therapeutic promise for gum disease and other inflammatory bone loss diseases. [CREDIT: A. SHAH/CORBIS] ...
Method: Before surgery, a composite restoration filled the deepest portion of the NCCL defects and was finished at the level of the maximum root coverage (MRC). The surgical technique adopted for the root coverage procedures was CAF for MGRs without vertical releasing incisions in the maxilla, and with one vertical releasing incision in the mandible. The CM was positioned at the level of the cementoenamel junction (CEJ), and sutured at the base of the anatomic de-epithelialized papillae. The flap was shifted coronally, providing complete coverage of the CM, and sutured coronal to the CEJ with a variable number of sling sutures ...
Straumann has released their new implant - the `bone level` implant. It features the SLActive surface all the way up to the top of the implant. The abutments are anatomically shaped and feature a `platform-switching` concept. It appears that this design is a response to concerns regarding esthetics and recession with implants in the esthetic zone. Straumann reports that `Intermediate data from the first clinical study show excellent esthetic results with regard to both hard and soft tissues indicating a low risk for recession and no esthetic complications.` The BLI implant is available in a limited market release in the US.. ...
3 Brånemark type external implants were placed in the left maxillary posterior area with sinus graft (left). 8 years later, an advanced chronic periimplantis with severe bone loss around the implant was found in the middle implant area (right ...
Health, ...Bone loss around dental implants is far more common than previously re...The study analysed X-rays of over 600 patients. The more implants a pa... Contrary to what we had previously assumed the bone loss in these pa...Smoking is one of several factors that increase the risk of bone loss....,1,in,4,patients,have,lost,bone,around,their,implants,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Principal Investigator:TSUKUBA Tomoko, Project Period (FY):2004 - 2005, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Functional basic dentistry
Normal Periodontium and its components including gingiva, periodontal ligament, cementum, alveolar bone. Formation, classification and functions of these components.
Health,According to recent study researchers have found that bone loss can b... They looked at 15 women and men who had received potassium citrat......,Bone,loss,can,be,reduced,by,Potassium,,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Buried in yesterdays post was the news that Ive been diagnosed with osteoporosis. Yup, just when things are starting to look up, I discover a new problem that will take a long time to heal from. The good news is that at my age it is possible to reverse bone loss and rebuild my skeletal…
Use of an anti-IL-20 antibody, either alone or in combination with an anti-RANKL antibody, for treating breast cancer and inhibiting cancer-associated bone loss.
Well, the man in my lifes been sick for about two days now. Last night, he slept really early, around 9ish (thats early for him, as he usually sleeps between 12MN and 2AM). He told me that the weather was bad the day before. Hes Singaporean- hes used to drizzly weather. My guess is that when he says that the weathers bad, its really bad.. Poor honey was sick all day today. Lucky I was on Globe Powersurf these past few days, thats how I got to Whatsapp with him. Poor guy couldnt even finish his food. I, meanwhile, was suffering from alveolar bone ouchy from a braces adjustment. The only difference was that I could eat, if eating meant just swallowing everything.. Sometimes he thinks that effervescent vitamin Cs solve everything, but today, I pretty much dragged him to the doctor with ny superb word-typing skills. I had to bargain with him, because it was really obvious how he didnt want to go. He was even like, "What am I supposed to tell the doctor?". I being a self-proclaimed HPI ...
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Definition of guided tissue regeneration in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is guided tissue regeneration? Meaning of guided tissue regeneration as a legal term. What does guided tissue regeneration mean in law?
Successful osseointegration is the result of a controlled foreign body reaction to dental implants. Osseointegrated implants have demonstrated excellent long-term survivability, although they may be subject to limited marginal bone loss. Marginal bone loss during the first few years after implant placement seldom represents disease, but is instead the result of an adaptive bone response to surgical trauma and implant loading. It is not uncommon for implants with early marginal bone loss to enter a long-lasting state of bone stability. Extensive bone resorption after the first year is generally due to an exacerbation of adverse body reactions caused by non-optimal implant components, adverse surgery or prosthodontics and/or compromised patient factors. Disease in the form of peri-implantitis is a late complication that affects some implants with suppuration and rapid loss of crestal bone, and is probably caused by bacterial pathogens and immunological reactions. Unfortunately, the literature is ...
PURPOSE: Scalloped implants were developed to better maintain marginal bone. Therefore, this study evaluated marginal bone levels (MBLs) and soft tissue around single implants with scalloped necks in the esthetic zone prospectively over a 3-year period. MBLs were compared to those of conventional flat-platform implants at 1 and 3 years. MATERIALS AND METHODS: Patients received anterior single-tooth implants and were divided into two groups; the test group included implants with a scalloped neck design and the control group included conventional rough-surface implants with external hex. MBLs were compared radiographically at 1 and 3 years after crown insertion. For the test group, soft and hard tissue assessments were made at six different time points, beginning at abutment connection. Mesial and distal interproximal papillae and probing depths were assessed clinically. Data were analyzed with the Student t test and repeated measures analysis of variance on ranks (P , .05). RESULTS: Twenty-four ...
Garden City Dentist specializing in full dental care. Dr. Angela P. Kapetanos is a well-trained Garden City Dentist specializing in Osseous Grafting / Guided Tissue Regeneration .
Find out if guided tissue regeneration can help you regrow lost jaw bone structure by calling our dentists office in Frisco, TX, today at (972) 335-7100.
Abstract An implant-abutment interface at the alveolar bone crest is associated with sustained peri-implant inflammation; however, whether magnitude of inflammation is proportional..
Periodontitis is a common disease that is characterized by resorption of the alveolar bone and mediated by commensal bacteria that trigger host immune responses and bone destruction through unidentified mechanisms. We report that Nod1, an innate intracellular host receptor for bacterial peptidoglycan-related molecules, is critical for commensal-induced periodontitis in a mouse model. Mice lacking Nod1 exhibit reduced bone resorption as well as impaired recruitment of neutrophils to gingival tissues and osteoclasts to the alveolar bone, which mediate tissue and bone destruction. Further analysis showed that accumulation of a Nod1-stimulating commensal bacterium, NI1060, at gingival sites was sufficient to induce neutrophil recruitment and bone resorption. Genomic sequencing revealed that NI1060 is a mouse-specific bacterium that is related to bacteria associated with the development of aggressive periodontitis in humans. These findings provide insight into commensal-host interactions contributing ...
Long-term stability of early implant placement with contour augmentation.. Buser D, Chappuis V, Kuchler U, Bornstein MM, Wittneben JG, Buser R, Cavusoglu Y, Belser UC.. J Dent Res. 2013 Dec;92(12 Suppl):176S-82S. doi: 10.1177/0022034513504949. Epub 2013 Oct 24. PMID: 24158332. Clinical and Radiologic Outcomes after Submerged and Transmucosal Implant Placement with Two-Piece Implants in the Anterior Maxilla and Mandible: 3-Year Results of a Randomized Controlled Clinical Trial.. Sanz M, Ivanoff CJ, Weingart D, Wiltfang J, Gahlert M, Cordaro L, Ganeles J, Bragger U, Jackowski J, Martin WC, Jung RE, Chen S, Hammerle C. Clin Implant Dent Relat Res. 2013 Jul 9. doi: 10.1111/cid.12107. [Epub ahead of print] PMID: 23837502. A prospective noninterventional study to document implant success and survival of the Straumann Bone Level SLActive dental implant in daily dental practice.. Filippi A, Higginbottom FL, Lambrecht T, Levin BP, Meier JL, Rosen PS, Wallkamm B, Will C, Roccuzzo M. Quintessence Int. 2013 ...
The most recent development in periodontal regeneration is the use of proteins to induce the formation of tooth supporting structures lost to periodontal disease. Available since 1999, the procedure calls for placing embryonic cells into the defect, which in turn stimulate production of new bone and tissue cells which reform the normal periodontal complex. These cells are porcine (pig), and carry no risk of disease transmission. While long-term studies are not yet available, the research to date warrants use of this approach under certain circumstances. (See Emdogain) The periodontist must decide in each case whether the chances of improvement warrant the added expense of bone regeneration. However, restoring bone and the periodontal complex is the gold standard, and periodontal regeneration is being used more and more ...
Results: Five treated patients did not fit the original inclusion criteria: 4 because they were not affected by the present definition of peri-implantitis and 1 due to being treated with antibiotics. However, they were included according to an intention-to-treat-analysis concept. Nine patients of the LAD group were treated surgically versus 10 control patients. After 1 year, 3 patients dropped out, all from the LAD group. One implant treated with the LAD therapy failed versus none of the control group. Four complications occurred: 3 in 3 patients of the LAD group and 1 in the control group. Recurrence of peri-implantitis defined as 2 mm of peri-implant bone loss or more recorded on standardised periapical radiographs was observed in 6 patients, 3 from each group. In total, 29 implants were re-treated 1 to 4 times in the LAD group versus 33 implants 1 to 4 times in the control group; the difference was not statistically significant. Peri-implant marginal bone levels remained stable up to 1 year ...
Yes. Theres a lot of discussion about it. So, first of all, its a risk factor. So, often, when you see p. gingivalis, or when you see periodontitis, you often see, also, other diseases like diabetes. So, but, they showed the association. But the problem is: both diseases; or a lot of diseases, like cardiovascular diseases; are so complex and caused by different factors, thats its very difficult to find 1 cause or 1 relation. So, there has never been a causal relationship that has been demonstrated. So, what I can say is, maybe, if you have periodontitis with p. gingivalis, there are studies that demonstrate, so: the invasiveness of p. gingivalis. It can go to the liver, and there it can interact with the process of the glucose mechanism. So, the invasiveness, first of all: p. gingivalis makes that it may ... yes, I would say: induce the diabetes. But, on the other hand; you see, for diabetes patients, the problem is there: they may have a loss in bone density. And when you see to the ...
The Contour Healer® Straumann™ RC Bone Level Compatible product line includes dental abutments designed to serve as a temporary dental prosthesis during the healing process until a permanent crown is made ...
At LaBell Dentistry in Woodinville, WA, we bring you into a discerning family of patients that value a compassionate touch. Your input matters here. Dr. LaBells guidance offers you the freedom to choose a course of treatment that fits you best. Contact us today at 425.402.1246.
Microimplants ranging from 1.2 to 1.6 mm in diameter are small enough to be placed at most anatomical locations in the mouth, including the palate, chin, retromolar area, and interradicular spaces between teeth roots. After placement, at least 6 mm of the total length of the microimplant should be embedded into the bone in the maxilla and 4 mm in the mandible. The author typically prefers to use microimplants 7 to 8 mm long in the maxillary buccal alveolar bone and 5 to 6 mm long in the mandibular buccal side. In the maxillary palatal alveolar bone, 10- to 12-mm-long microimplants need to be placed to compensate for the thick palatal soft tissue and to keep 6 mm of microimplants embedded in the bone. The most common diameter of the microimplants is 1.3 mm in the maxilla and 1.4 mm in the mandible and 1.5 or 1.6 mm in the midpalatal area where there are no teeth. ...
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An endoscopic instrument for the application of ligature binders and a ligature are described. A base body and an actuation part of a handle part are longitudinally displaceable relative to each other against an elastic force within a fixed range. Connected to the actuation part is an actuation rod at whose distal end a first ratchet heat is secured. A shaft, firmly connected to the base body, carries a second ratchet head at its distal end. With the help of the ratchet heads, which are matched to the toothed end zone of a ligature binder, a ligature can be drawn together. A ligature whose end zone has already been inserted into the endoscopic instrument prior to the operation can be brought into a closed shape with the help of a constricted zone in its binding part and of a longitudinal slot in its headpiece.
Principal Investigator:HOSOKAWA Ryuji, Project Period (FY):2002 - 2003, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:補綴理工系歯学
Three-dimensional (3D) printing has been applied extensively not only in human, but also veterinary medicine. However, the technique is still used in the clinical area for a surgical plan or education prior to surgery. Thus, we report a case of reconstruction after tumor removal surgery with the use of a 3D-printed scaffold. A 12-year-old female mixed dog had a left caudal maxillary mass. Based on computed tomography images, a defect was confirmed on the maxillary bone due to the oral mass, and a surgical plan was designed to remove the oral mass and graft the 3D printed scaffold ...
Discussion The mental foramen has been used as a point of reference in morphometric analyses of the mandible, by virtue of its stable relation with the base of this bone (Neiva et al., 2004). In this study, the mean values of the distances between the image of the mental foramen and the mandible base (D1), and of this foramen to the alveolar crest (D2) had no statistically significant differences between the analyzed age groups, confirming the stability of this relation throughout the individuals adult life. The mean values of R1 (D1/D2) did not differ statistically between the four studied groups indicating that it is constant. There are records in the literature that the stability of D1 not depend on the reabsorption of the alveolar process in the region above of the foramen, and that the vertical measurements in panoramic radiography are clinically applicable for quantification of the height of the alveolar bone in this region (Lindh et al.; Güller et al.). The mean values of the ratios ...
A pocket is a dental term that indicates the presence of an abnormal sulcus in the gums, separating them from teeth. A periodontal pocket occurs when a person suffers from periodontal disease and there is loss of alveolar bone under the gums.
The Rovner P-1RL Platinum Alto Saxophone Ligature is a piece of metal ligature that includes a Rovner Cap. Producing a pure, dark, tone this ligature creates a ringing bell-like sound and enables effortless playing with an evenness of scale, smoothing out the difficult transitions between registers. Providing you with superior control for a secure, centered tone and flawless intonation, the Platinum Ligature allows for unprecedented reed-gripping capabilities.
Glass Science and its Applications: Application of Glass Reinforced Hydroxyapatite Composite in the Treatment of Human Intrabony Periodontal Angular Defects - Two Case Reports
A research study from Norway has confirmed a link between psoriasis and gum disease. The study found that people with psoriasis had an increased likelihood of also having periodontitis, a severe form of gum disease. Loss of the alveolar bone, the bone that forms the tooth …. Read More ...
Papillon-Lefevre syndrome. Coloured transmission electron micrograph (TEM) of a cell affected by Papillon-Lefevre syndrome, a rare inherited condition. Plaques of the protein keratin (blue) are seen within the cell. The disease causes hyperkeratosis (thickening of the skin) and severe periodontitis, an inflammation of the tissue that surrounds and supports the teeth. The inflammation results in bone and tooth loss. Magnification: x16,600 when printed at 10 centimetres wide. - Stock Image C020/8722
DOI: 10.11607/jomi.4594 Purpose: Concerns have been expressed about the possibility of high insertion torque (IT) causing necrosis, impaired osseointegration, and crestal bone loss over time. The present study investigated the relationship between primary stability and implant success, including early and late maintenance of crestal bone levels. Materials and Methods: Implants were placed in patients at three study centers. Every effort was made to achieve the highest possible primary stability, which was measured with IT and implant stability quotient (ISQ). The IT and ISQ at insertion and reopening (3 to 4 months), as well as bone levels at several points in time, were recorded. The correlations between IT, ISQ, and immediate and 3-year crestal bone loss were investigated through linear regression analyses. Results: Average IT was 76.1 20.8 Ncm, while the average ISQ score was 80.4 8.4. The implant success rate at 36 months was 98.6%. The crestal bone loss around most implants (41.0%) ranged ...
Regenerate lost gum & bone tissue with guided tissue regeneration from Periodontist Dr. Westbrook in Sunnyvale CA. Call 408-737-1551 or visit our Website.
Figures 5-10: 5. Full-thickness flap divulsion. 6. Disinfection of the surgical cavity with PDT. 7. Radiographic follow-up of the right central incisor (12-month control). 8. Clinical aspect of the left lateral incisor after curettage. The presence of a bony defect surrounding the tooth and apical root resorption were observed (arrow). 9. Filling of the surgical cavity with calcium sulfate. 10. Radiographic follow-up of the left lateral incisor (12-month control. According to some authors,2,4,14 peri-radicular surgery success rates have significantly evolved over the past few decades, with the improvement of retrofilling materials, ultrasonic preparation, and the use of magnification during the endodontic procedures. Periradicular surgery also offers the opportunity to retrieve tissue for histologic and microbiologic analysis,2 contributing to the diagnosis. Nevertheless, Lieblich2 explains that in cases with an expected poor success rate, such as the presence of severe periodontal bone loss ...
MAYWOOD, Il. - Osteoporosis is a growing concern among breast cancer survivors and their doctors, because certain cancer drugs can cause bone loss.. Many breast cancer patients also experience secondary causes of bone loss, such as vitamin D deficiency.. But a Loyola University Health System study has found that bone loss can be halted with a comprehensive regimen that includes both osteoporosis drugs and treatments that target secondary causes of bone loss.. The study by Dr. Pauline Camacho and colleagues was presented at the annual meeting of the American Society for Bone and Mineral Research.. "Doctors evaluating breast cancer patients for possible bone loss should look further than cancer drugs," Camacho said.. Primary causes of osteoporosis are menopause and aging. Secondary causes are diseases or conditions that exacerbate bone loss.. A class of breast cancer drugs called aromatase inhibitors can decrease bone mineral density and increase the risk of fractures in postmenopausal women. The ...

Development of novel tools for prevention and diagnosis of Porphyromonas gingivalis infection and periodontitisDevelopment of novel tools for prevention and diagnosis of Porphyromonas gingivalis infection and periodontitis

... host immune responses to dysregulated microbiota in dental biofilms leading to degradation of tissues and alveolar bone loss. ...
more infohttp://oru.diva-portal.org/smash/record.jsf?pid=diva2:967367

B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral InfectionB Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection

Immune responses to infection trigger loss of alveolar bone from the jaw and eventual tooth loss. We investigated the ... B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection. Pamela J. Baker,1 Nicole Ryan Boutaugh,1 ... contribution of B cell IgD to alveolar bone loss by comparing the response of B cell normal BALB/cJ mice and IgD deficient BALB ... Specific antibody to P. gingivalis was lower and oral colonization was higher in IgD deficient mice; yet bone loss was ...
more infohttps://www.hindawi.com/journals/ipid/2009/864359/abs/

topic:Alveolar Bone Loss - epidemiology found 49 records • Arctic Healthtopic:"Alveolar Bone Loss - epidemiology" found 49 records • Arctic Health

... severe alveolar bone loss ranging between 1/3 and 2/3 of the normal alveolar bone height (group 4), or alveolar bone loss ... gingivitis without signs of alveolar bone loss (group 2), moderate alveolar bone loss not exceeding 1/3 of the normal alveolar ... Mean alveolar bone loss varied between 1.51 mm and 2.64 mm depending on smoking status and age. Mean alveolar bone loss was ... Alveolar bone loss was recorded if the distance from the cemento-enamel junction to the alveolar crest exceeded 2 mm measured ...
more infohttps://arctichealth.org/en/list?q=topic%3A%22Alveolar+Bone+Loss+-+epidemiology%22&p=1&ps=&sort=title_sort+asc

Paper: Bis-enoxacin Inhibited Alveolar Bone Loss and Gingival Inflammation in Rats (AADR Annual Meeting (March 21-24, 2012))Paper: Bis-enoxacin Inhibited Alveolar Bone Loss and Gingival Inflammation in Rats (AADR Annual Meeting (March 21-24, 2012))

403 Bis-enoxacin Inhibited Alveolar Bone Loss and Gingival Inflammation in Rats Thursday, March 22, 2012: 2 p.m. - 3:15 p.m. ... and alendronate in inhibiting osteoclast alveolar bone resorption (ABR) in a polymicrobial periodontal disease rat model. ... Similarly, enoxacin-linked bisphosphonate, bis-enoxacin, inhibits osteoclast formation and bone resorption. Periodontal ...
more infohttp://www-personal.umich.edu/~sbayne/DMG/DMG-Publications/IADR-AADR-Meeting-Program-Books/2012-AADR-Tampa/2012-AADR-Tampa-CD/AADR12/Paper156129.html

Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss - Full Text View ...Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss - Full Text View ...

Quantify periodontal alveolar bone loss rates in postmenopausal women.. II. Evaluate the effects of estrogen on alveolar bone ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. The safety and ... Comparison of reliability of manual and computer-intensive methods for radiodensity measures of alveolar bone loss. ... loss rates in these patients.. III. Determine whether changes in periodontal bone mass relate to bone mass changes in other ...
more infohttps://clinicaltrials.gov/show/NCT00004650

Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss - Tabular View -...Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss - Tabular View -...

Quantify periodontal alveolar bone loss rates in postmenopausal women.. II. Evaluate the effects of estrogen on alveolar bone ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. The safety and ... Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss. ... Comparison of reliability of manual and computer-intensive methods for radiodensity measures of alveolar bone loss. ...
more infohttps://clinicaltrials.gov/ct2/show/record/NCT00004650

Alveolar bone loss and ageing: possible association with coronary heart diseases and/or severe vascular diseasesAlveolar bone loss and ageing: possible association with coronary heart diseases and/or severe vascular diseases

... ... as well as severe hypertension and alveolar bone loss (ABL) in older adults. ... Direct measures of alveolar bone level were recorded using CT scans, and different variables were studied (age, sex, Plaque ... The results confirmed a positive association between CHD/VD and periodontal destruction; alveolar bone destruction represented ...
more infohttps://insights.ovid.com/gero/201609000/01445423-201609000-00011

Effect of obesity on alveolar bone loss in experimental periodontitis in Wistar ratsEffect of obesity on alveolar bone loss in experimental periodontitis in Wistar rats

Morphometric registration of alveolar bone loss was carried out after 30 days of ligature placement to determine the effect of ... Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental ... Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental ... Effect of obesity on alveolar bone loss in experimental periodontitis in Wistar rats. ...
more infohttps://lume.ufrgs.br/handle/10183/61179

Effect of Ratio of Residual Alveolar Bone to Graft Material in Contact With Fixture Surface on Marginal Bone Loss of Implants...Effect of Ratio of Residual Alveolar Bone to Graft Material in Contact With Fixture Surface on Marginal Bone Loss of Implants...

Effect of Ratio of Residual Alveolar Bone to Graft Material in Contact With Fixture Surface on Marginal Bone Loss of Implants ... The residual bone/implant length ratio and the residual bone/implant area ratio were not associated with marginal bone loss at ... The residual bone/implant length ratio and residual bone/implant area ratio were not associated with marginal bone loss around ... study was to evaluate the influences of height or area ratio of residual alveolar bone to graft material on marginal bone loss ...
more infohttps://insights.ovid.com/imden/201702000/00008505-201702000-00013

KAKEN - Research Projects | Analysis of bone remodeling mechanism between osteoblasts and osteoclasts for the alveolar bone...KAKEN - Research Projects | Analysis of bone remodeling mechanism between osteoblasts and osteoclasts for the alveolar bone...

RANKL-Tg mice exhibit osteopenia characterized by excessive bone resorption. Alveolar bone loss in OPG KO mice and RANKL-Tg ... Treatment with an anti-RANKL antibody as well as risedronate, a bisphosphonate, significantly inhibited the alveolar bone loss ... Journal Article] Osteoprotegerin-deficient male mice as a model for severe alveolar bone loss: Comparison with RANKL- ... Analysis of bone remodeling mechanism between osteoblasts and osteoclasts for the alveolar bone regeneration. Research Project ...
more infohttps://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-24390417/

In-Vivo Effect of Andrographolide on Alveolar Bone Resorption Induced by Porphyromonas gingivalis and Its Relation with...In-Vivo Effect of Andrographolide on Alveolar Bone Resorption Induced by Porphyromonas gingivalis and Its Relation with...

The area of alveolar bone loss was evaluated morphometrically by measuring the distance between the CEJ to the alveolar bone ... Evaluation of Alveolar Bone Resorption. Alveolar bone resorption of the left and right sides of the mandible was assessed by a ... Risk indicators for alveolar bone loss," Journal of Periodontology, vol. 66, no. 1, pp. 23-29, 1995. View at Google Scholar · ... Since the results indicate that a high dose of AND has reduced the amount of alveolar bone loss compared to low dose. Pg caused ...
more infohttps://www.hindawi.com/journals/bmri/2013/276329/

AMFS | Periodontics Expert Witness - Personal Injury/Malpractice LawsuitsAMFS | Periodontics Expert Witness - Personal Injury/Malpractice Lawsuits

Untreated, it often leads to tooth loss and alveolar bone loss.. Call today (or complete the contact form) for a free ... The supporting tissues are known as the periodontium, which includes the gingiva (gums), alveolar bone, cementum, and the ...
more infohttps://www.amfs.com/experts/specialties/periodontics-experts/

Clinical diagnosis in periodontologyClinical diagnosis in periodontology

Alveolar bone lossAlveolar bone levels are evaluated by clinical and radiographic examination. • Probing is helpful for ... The periodontal pocket is a soft tissue change • Radiographs indicate areas of bone loss where pockets may be suspected but : 1 ... Changes in the level of attachment can be due only to gain or loss of attachment and afford a better indication of the degree ... If both are the same, the loss of attachment is zero • When the gingival margin coincides with the cementoenamel junction, the ...
more infohttps://www.slideshare.net/pshycopathetic/clinical-diagnosis-in-periodontology

Dr. Mark Looney, DDS - Texarkana, TX - Dentistry | Healthgrades.comDr. Mark Looney, DDS - Texarkana, TX - Dentistry | Healthgrades.com

Alveolar Bone Loss. *Anodontia. *Bad Taste in Mouth. *Bleeding Gums. *Bonding Disorders ...
more infohttps://www.healthgrades.com/dentist/dr-mark-looney-2vltb

Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of...Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of...

Detection of rat alveolar bone damage by stereomicroscopy and immunohistochemical staining. (a) and (b) Alveolar bone loss in ... Alveolar bone loss was inhibited by 100 μg/mL or 400 μg/mL of Nal-P-113 compared to the control group (P , 0.05). Lower amounts ... LST performed the alveolar bone loss analysis. JWC and YPP designed the study and drafted the manuscript. All authors read and ... Alveolar bone loss is a typical characteristic of periodontitis and is usually used as a marker of periodontitis in this model ...
more infohttps://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-017-1931-9/

Direct Recognition of Fusobacterium nucleatum by the NK Cell Natural Cytotoxicity Receptor NKp46 Aggravates Periodontal DiseaseDirect Recognition of Fusobacterium nucleatum by the NK Cell Natural Cytotoxicity Receptor NKp46 Aggravates Periodontal Disease

Quantification of alveolar bone loss. For quantitative 3-dimensional analysis of the alveolar bone loss, the hemi-maxillae were ... no loss of alveolar bone around the teeth is observed, while when mice were infected with P. gingivalis bone loss was observed ... gingivalis and the levels of alveolar bone loss were quantified by micro-CT ([38], [39], Figure 1A). Around 20% bone loss was ... gingivalis also resulted in alveolar bone loss which was similar to that of F. nucleatum. However, this bone loss was observed ...
more infohttp://pubmedcentralcanada.ca/pmcc/articles/PMC3310798/

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Canadian Research Team to Study Markers of Alveolar Bone Loss. May 25, 2012 Topics: education / diagnosis / systemic disease / ...
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Canadian Research Team to Study Markers of Alveolar Bone Loss. May 25, 2012 Topics: education / diagnosis / systemic disease / ...
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Canadian Research Team to Study Markers of Alveolar Bone Loss. May 25, 2012 Topics: education / diagnosis / systemic disease / ...
more infohttps://www.jcda.ca/search?field_type%255B%255D=122&page=2&page=3

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Canadian Research Team to Study Markers of Alveolar Bone Loss. May 25, 2012 Topics: education / diagnosis / systemic disease / ...
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Periodontitis and diabetes: a two-way relationship | SpringerLinkPeriodontitis and diabetes: a two-way relationship | SpringerLink

... the periodontal ligament and alveolar bone). It is highly prevalent... ... pattern of bone loss. Some of the teeth have lost nearly all their supporting alveolar bone as a result of periodontitis ... Alveolar bone levels are normal, with the crest of the alveolar bone being in close proximity to the cemento-enamel junction ( ... Risk indicators for alveolar bone loss. J Periodontol 66:23-29PubMedCrossRefGoogle Scholar ...
more infohttps://link.springer.com/article/10.1007%2Fs00125-011-2342-y
  • The objective of this study was to utilise a new methodological approach based on radiographic examinations to demonstrate a potential association between coronary heart diseases (CHD) as well as severe hypertension and alveolar bone loss (ABL) in older adults. (ovid.com)
  • You won't find an environmental cause for any bone cancer apart from the rare ones that arise in pre-existing severe Paget's of bone, rare genetic syndromes or an old radiation port. (healthtap.com)
  • P. gingivalis -infected normal mice lost bone. (hindawi.com)
  • Alveolar bone loss in OPG KO mice and RANKL-Tg mice was evaluated using micro computed tomography and histological techniques. (nii.ac.jp)
  • OPG was highly expressed in osteocytes in the alveolar bone, suggesting that OPG secreted from osteocytes prevents the alveolar bone loss induced by the excess amount of RANKL in RANKL-Tg mice. (nii.ac.jp)
  • Treatment with an anti-RANKL antibody as well as risedronate, a bisphosphonate, significantly inhibited the alveolar bone loss in OPG KO mice. (nii.ac.jp)
  • Journal Article] Stimulation of bone formation in cortical bone of mice treated with a receptor activator of nuclear factor-kB ligand (RANKL)-binding peptide that possesses osteoclastogenesis inhibitory activity. (nii.ac.jp)
  • Using mice deficient in NCR1 (the mouse orthlogue of NKp46), we demonstrate that oral infection of mice with F. nucleatum , but not with P. gingivalis results in an NCR1-dependent alveolar bone loss. (pubmedcentralcanada.ca)
  • In this study, 42 patients with Astra implants in sinuses that had been augmented with alloplasts and allografts or xenografts (alveolar bone height ≤ 5 mm) were selected. (ovid.com)
  • The residual bone/implant length ratio and residual bone/implant area ratio were not associated with marginal bone loss around implants placed in augmented sinuses during 1 year of functional loading. (ovid.com)
  • Marginal bone level surrounding 1 implant per sinus was assessed by radiographic imaging at the time of final restoration delivery and 12 months after functional loading. (ovid.com)
  • What causes bone marrow tumors to form? (healthtap.com)
  • There are multiple different types of bone marrow tumors and the cause for almost all is unknown. (healthtap.com)
  • Increased IgE + B Cells in Sputum, but Not Blood, Bone Marrow, or Tonsils, after Inhaled Allergen Challenge in Subjects with Asthma. (nih.gov)
  • In healthy gums, the base of the pocket is coincident with the cemento-enamel junction (CEJ, the boundary between the enamel crown and the root) and there is no attachment loss. (springer.com)
  • The base of the pocket is therefore apical to the CEJ, and attachment loss can be measured (in mm, using a periodontal probe) from the CEJ to the base of the pocket. (springer.com)
  • Examiners blinded to diabetes status performed random half-mouth periodontal examinations, assessing probing depth (PD) and attachment loss (AL) (four sites/tooth) at baseline and follow-up. (diabetesjournals.org)
  • Assuming that alveolar bone loss is irreversible after smoking cessation, it could be hypothesized that there is a threshold period for tobacco smoking after which the accumulated effect of smoking becomes clinically observable. (arctichealth.org)
  • After a certain number of years of smoking, the effect on alveolar bone loss seems to level out. (arctichealth.org)
  • An 'S-shaped' relationship between smoking duration and alveolar bone loss: generating a hypothesis. (arctichealth.org)
  • Little is known about the relationship between smoking duration and alveolar bone loss. (arctichealth.org)
  • A dose-response model for duration of tobacco smoking on alveolar bone loss was then developed and discussed. (arctichealth.org)
  • Regression analyses were performed to study the relationship between smoking duration and alveolar bone loss. (arctichealth.org)
  • CONCLUSIONS: Our results generate the hypothesis that the relationship between smoking duration and alveolar bone loss was 'S-shaped. (arctichealth.org)
  • To test this hypothesis, the relationship between smoking duration and alveolar bone loss should be studied in a prospective study design. (arctichealth.org)
  • RESULTS: Mean alveolar bone loss varied between 1.51 mm and 2.64 mm depending on smoking status and age. (arctichealth.org)
  • Direct measures of alveolar bone level were recorded using CT scans, and different variables were studied (age, sex, Plaque index, cigarettes per day, coronary heart disease and vascular disease status). (ovid.com)
  • The bone level, that is, the distance from the alveolar bone crest to cementumenamel junction (CEJ), was measured using 6.1 : 1 zoom stereomicroscope and software. (hindawi.com)
  • Other bone lesions when enlarging such as dysplasias or giant cell tumors as preexisting lesions may result in malignant transformation. (healthtap.com)
  • Simple bone cyst is a common, benign, fluid-containing lesion, most commonly found in the metaphysis of long bones . (healthtap.com)