A species of replication-competent oncogene-containing virus in the genus ALPHARETROVIRUS. It is the original source of the src oncogene (V-SRC GENES) and causes sarcoma in chickens.
A genus of the family RETROVIRIDAE with type C morphology, that causes malignant and other diseases in wild birds and domestic fowl.
Retroviruses that have integrated into the germline (PROVIRUSES) that have lost infectious capability but retained the capability to transpose.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase. The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS; RETROVIRUSES TYPE D; and SPUMAVIRUS. A key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA. After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES).
Virus diseases caused by the RETROVIRIDAE.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
Nucleotide sequences repeated on both the 5' and 3' ends of a sequence under consideration. For example, the hallmarks of a transposon are that it is flanked by inverted repeats on each end and the inverted repeats are flanked by direct repeats. The Delta element of Ty retrotransposons and LTRs (long terminal repeats) are examples of this concept.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.
The systematic arrangement of entities in any field into categories classes based on common characteristics such as properties, morphology, subject matter, etc.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
Indolesulfonic acid used as a dye in renal function testing for the detection of nitrates and chlorates, and in the testing of milk.
A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).
A plant genus of the family Paeoniaceae, order Dilleniales, subclass Dilleniidae, class Magnoliopsida. These perennial herbs are up to 2 m (6') tall. Leaves are alternate and are divided into three lobes, each lobe being further divided into three smaller lobes. The large flowers are symmetrical, bisexual, have 5 sepals, 5 petals (sometimes 10), and many stamens.
The type species of LENTIVIRUS and the etiologic agent of AIDS. It is characterized by its cytopathic effect and affinity for the T4-lymphocyte.
Anomaly of the tooth, found chiefly in upper lateral incisors. It is characterized by invagination of the enamel at the incisal edge.
NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.
A species of mite that causes SCABIES in humans and sarcoptic mange in other animals. Specific variants of S. scabiei exist for humans and animals, but many have the ability to cross species and cause disease.
A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.
A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
A genus of the family RETROVIRIDAE consisting of viruses with either type B or type D morphology. This includes a few exogenous, vertically transmitted and endogenous viruses of mice (type B) and some primate and sheep viruses (type D). MAMMARY TUMOR VIRUS, MOUSE is the type species.
A superfamily of nematodes whose members are free-living saprophytes or parasites of plants. Ova are sometimes found in human feces after ingestion of infected plants.
Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is a DNA nucleotidyltransferase encoded by the pol gene.
Insertion of viral DNA into host-cell DNA. This includes integration of phage DNA into bacterial DNA; (LYSOGENY); to form a PROPHAGE or integration of retroviral DNA into cellular DNA to form a PROVIRUS.
Inhibitors of HIV INTEGRASE, an enzyme required for integration of viral DNA into cellular DNA.
Ribonucleic acid that makes up the genetic material of viruses.
Deoxyribonucleic acid that makes up the genetic material of viruses.
The malignant stem cells of TERATOCARCINOMAS, which resemble pluripotent stem cells of the BLASTOCYST INNER CELL MASS. The EC cells can be grown in vitro, and experimentally induced to differentiate. They are used as a model system for studying early embryonic cell differentiation.
The largest of the three pairs of SALIVARY GLANDS. They lie on the sides of the FACE immediately below and in front of the EAR.
A group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans. (Stedman, 25th ed) EC 3.2.1.-.
A highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad and rarely in other sites. It is rare in the female ovary, but in the male it accounts for 20% of all testicular tumors. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, p1595)
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.
A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)
Family of the suborder HAPLORHINI (Anthropoidea) comprising bipedal primate MAMMALS. It includes modern man (HOMO SAPIENS) and the great apes: gorillas (GORILLA GORILLA), chimpanzees (PAN PANISCUS and PAN TROGLODYTES), and orangutans (PONGO PYGMAEUS).
A strain of PRIMATE T-LYMPHOTROPIC VIRUS 1 isolated from mature T4 cells in patients with T-lymphoproliferation malignancies. It causes adult T-cell leukemia (LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-I-ASSOCIATED), T-cell lymphoma (LYMPHOMA, T-CELL), and is involved in mycosis fungoides, SEZARY SYNDROME and tropical spastic paraparesis (PARAPARESIS, TROPICAL SPASTIC).
A strain of PRIMATE T-LYMPHOTROPIC VIRUS 2 that can transform normal T-lymphocytes and can replicate in both T- and B-cell lines. The virus is related to but distinct from HTLV-1.
A strain of PRIMATE T-LYMPHOTROPIC VIRUS 2, closely related to the human HTLV-1 virus. The clinical, hematological, and histopathological characteristics of the disease in STLV-infected monkeys are very similar to those of human adult T-cell leukemia. Subgroups include the African green monkey subtype (STLV-I-AGM), for which the nucleotide sequence is 95% homologous with that of HUMAN T-LYMPHOTROPIC VIRUS 1, and the Asian rhesus macaque subtype (STLV-I-MM), for which the nucleotide sequence is 90% homologous with that of HUMAN T-LYMPHOTROPIC VIRUS 1.
A strain of PRIMATE T-LYMPHOTROPIC VIRUS 3 that is genetically similar to STLV-3.
Infections caused by the HTLV or BLV deltaretroviruses. They include human T-cell leukemia-lymphoma (LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-I-ASSOCIATED).
The profession of writing. Also the identity of the writer as the creator of a literary production.
Forms of combined immunodeficiency caused by mutations in the gene for INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT. Both severe and non-severe subtypes of the disease have been identified.
Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.

Production and characterization of a soluble, active form of Tva, the subgroup A avian sarcoma and leukosis virus receptor. (1/332)

The receptor for the subgroup A avian sarcoma and leukosis viruses [ASLV(A)] is the cellular glycoprotein Tva. A soluble form of Tva, sTva, was produced and purified with a baculovirus expression system. Using this system, 7 to 10 mg of purified sTva per liter of cultured Sf9 cells was obtained. Characterization of the carbohydrate modification of sTva revealed that the three N glycosylation sites in sTva were differentially utilized; however, the O glycosylation common to Tva produced in mammalian and avian cells was not observed. Purified sTva demonstrates significant biological activity, specifically blocking infection of avian cells by ASLV(A) with a 90% inhibitory concentration of approximately 25 pM. A quantitative enzyme-linked immunosorbent assay, developed to assess the binding of sTva to ASLV envelope glycoprotein, demonstrates that sTva has a high affinity for EnvA, with an apparent dissociation constant of approximately 0.3 nM. Once they are bound, a very stable complex is formed between EnvA and sTva, with an estimated complex half-life of 6 h. The soluble receptor protein described here represents a valuable tool for analysis of the receptor-envelope glycoprotein interaction and for structural analysis of Tva.  (+info)

Substitutions in the receptor-binding domain of the avian sarcoma and leukosis virus envelope uncouple receptor-triggered structural rearrangements in the surface and transmembrane subunits. (2/332)

The retrovirus avian sarcoma and leukosis virus (ASLV) enters cells via pH-independent membrane fusion. This reaction is catalyzed by the viral glycoprotein Env, composed of a membrane-distal subunit, SU, and a membrane-anchored subunit, TM. Previous mutational analysis of a variable region, central within the SU subunit, indicates that this region constitutes part of the receptor-binding domain for subgroup A envelope (EnvA) and furthermore that basic residues (R210, R213, R223, R224, and K227) within this region are critical determinants of efficient ASLV infection. Substitutions of these basic residues exert effects on both receptor binding and postbinding events in EnvA-mediated entry. In this study, we performed biochemical analysis of the EnvA protein from three of the receptor-binding domain mutants (R213A/K227A, R213A/R223A/R224A, and R213S) to define the role of this domain in early molecular events in the entry pathway. Protease sensitivity assays demonstrated that receptor binding was sufficient to trigger conformational changes in the SU subunit of mutants R213A/K227A and R213S similar to those in the wild-type EnvA, while R213A/R223A/R224A was constitutively sensitive to protease. In contrast, all three receptor-binding domain mutants disrupted receptor-triggered conversion of EnvA to an active, membrane-binding conformation as assessed by liposome flotation assays. Our results demonstrate that mutations in the receptor-binding site can dissociate receptor-triggered conformational changes in the SU subunit from membrane binding. Furthermore, they suggest that communication between the receptor-binding subunit, SU, and the fusogenic subunit, TM, is crucial for efficient activation of the fusogenic state of EnvA. Analysis of these mutants continues earlier observations that binding to the cellular receptor provides the trigger for efficient activation of this pH-independent viral envelope protein.  (+info)

Development of a flexible and specific gene delivery system for production of murine tumor models. (3/332)

To develop models of human cancer we have expressed the avian retroviral receptor, TVA, under a variety of mammalian promoters in transgenic mice, thus rendering mice susceptible to infection with avian leukosis virus-derived gene vectors. TVA-based retroviral gene transfer offers advantages over current murine models of human cancer. A single transgenic mouse line can be used to evaluate multiple genetic lesions, individually and in combination. Furthermore, mutant genes are introduced somatically into animals, as occurs in the majority of naturally occurring tumors. Because the avian viral vectors replicate only in avian cells, the viral receptor in infected transgenic mouse cells remains available for multiple rounds of infection with different ASLV vectors. We discuss the theoretical and practical aspects of using recombinant avian retroviruses with TVA transgenic mice to generate cancer models.  (+info)

An Mpsi-containing heterologous RNA, but not env mRNA, is efficiently packaged into avian retroviral particles. (4/332)

Retroviruses preferentially package full-length genomic RNA over spliced viral messages. For most retroviruses, this preference is likely due to the absence of all or part of the packaging signal on subgenomic RNAs. In avian leukosis-sarcoma virus, however, we have shown that the minimal packaging signal, MPsi, is located upstream of the 5' splice site and therefore is present on both genomic and spliced RNAs. We now show that an MPsi-containing heterologous RNA is packaged only 2.6-fold less efficiently than genomic Rous sarcoma virus RNA. Thus, few additional packaging sequences and/or structures exist outside of MPsi. In contrast, we found that env mRNA is not efficiently packaged. These results indicate that either MPsi is not functional on this RNA or the RNA is somehow segregated from the packaging machinery. Finally, deletion of sequences from the 3' end of MPsi was found to reduce the packaging efficiency of heterologous RNAs.  (+info)

Secondary structure analysis of a minimal avian leukosis-sarcoma virus packaging signal. (5/332)

We previously identified a 160-nucleotide packaging signal, MPsi, from the 5' end of the Rous sarcoma virus genome. In this study, we determine the secondary structure of MPsi by using phylogenetic analysis with computer modeling and heterologous packaging assays of point mutants. The results of the in vivo studies are in good agreement with the computer model. Additionally, the packaging studies indicate several structures which are important for efficient packaging, including a single-stranded bulge containing the initiation codon for the short open reading frame, uORF3, as well as adjacent stem structures. Finally, we show that the L3 stem-loop at the 3' end of MPsi is dispensable for packaging, thus identifying an 82-nucleotide minimal packaging signal, microPsi, composed of the O3 stem-loop.  (+info)

The central proline of an internal viral fusion peptide serves two important roles. (6/332)

The fusion peptide of the avian sarcoma/leukosis virus (ASLV) envelope protein (Env) is internal, near the N terminus of its transmembrane (TM) subunit. As for most internal viral fusion peptides, there is a proline near the center of this sequence. Robson-Garnier structure predictions of the ASLV fusion peptide and immediate surrounding sequences indicate a region of order (beta-sheet), a tight reverse turn containing the proline, and a second region of order (alpha-helix). Similar motifs (order, turn or loop, order) are predicted for other internal fusion peptides. In this study, we made and analyzed 12 Env proteins with substitutions for the central proline of the fusion peptide. Env proteins were expressed in 293T cells and in murine leukemia virus pseudotyped virions. We found the following. (i) All mutant Envs form trimers, but when the bulky hydrophobic residues phenylalanine or leucine are substituted for proline, trimerization is weakened. (ii) Surprisingly, the proline is required for maximal processing of the Env precursor into its surface and TM subunits; the amount of processing correlates linearly with the propensity of the substituted residue to be found in a reverse turn. (iii) Nonetheless, proteolytically processed forms of all Envs are preferentially incorporated into pseudotyped virions. (iv) All Envs bind receptor with affinity greater than or equal to wild-type affinity. (v) Residues that support high infectivity cluster with proline at intermediate hydrophobicity. Infectivity is not supported by mutant Envs in which charged residues are substituted for proline, nor is it supported by the trimerization-defective phenylalanine and leucine mutants. Our findings suggest that the central proline in the ASLV fusion peptide is important for the formation of the native (metastable) Env structure as well as for membrane interactions that lead to fusion.  (+info)

Soluble receptor-induced retroviral infection of receptor-deficient cells. (7/332)

Current models of retroviral entry hypothesize that interactions between the host cell receptor(s) and viral envelope protein induce structural changes in the envelope protein that convert it to an active conformation, allowing it to mediate fusion with the membrane. Recent evidence supporting this hypothesis is the demonstration that Tva, the receptor for subgroup A avian sarcoma and leukosis virus (ASLV-A), induces conformational changes in the viral envelope protein. These changes include conversion of the envelope protein to an active, membrane-binding state likely representing a fusogenic conformation. To determine whether binding of the soluble Tva (sTva) receptor was sufficient to activate fully the fusogenic potential of the ASLV-A envelope protein, we have evaluated the ability of ASLV-A to infect receptor-deficient cell lines in the presence of sTva. Soluble receptor efficiently mediated infection of cells devoid of endogenous Tva in a dose-dependent manner, and this infection was dependent absolutely on the addition of sTva. The infectivity of the virus was enhanced dramatically in the presence of the polycationic polymer Polybrene or when centrifugal forces were applied during inoculation, resulting in viral titers comparable to those achieved on cells expressing endogenous receptor. sTva functioned to mediate infection at low concentrations, approaching the estimated binding constant of the receptor and viral envelope protein. These results demonstrate that receptor binding can activate the ASLV-A envelope protein and convert it to a fusogenic conformation competent to mediate the fusion of the viral and cellular membranes.  (+info)

Selection of a subgroup A avian leukosis virus [ALV(A)] envelope resistant to soluble ALV(A) surface glycoprotein. (8/332)

The host developing resistance to retroviral infection is believed to be a major force in the evolution of multiple receptor usage by retroviruses. The avian leukosis-sarcoma virus (ALV) group of retroviruses provides a powerful system for studying the envelope-receptor interactions involved in retrovirus entry; different members of this group of closely related viruses use distinct cellular receptors. Analysis of the ALV envelope subgroups suggests that the different ALVs evolved from a common ancestor by mutations in the env gene. Cells and animals that express subgroup A ALV envelope glycoproteins are highly resistant to ALV(A) infection due to receptor interference. In this study, we tested whether expression of a soluble form of subgroup A surface glycoprotein (SU) would result in receptor interference and whether this interference would select for resistant viruses with altered receptor usage. Chicken cells expressing the secreted ALV(A) SU immunoadhesin SU(A)-rIgG, which contains the subgroup A SU domain fused to the constant region of a rabbit immunoglobulin (IgG) heavy chain, showed significant receptor interference. A variant virus resistant to SU(A)-rIgG receptor interference was obtained. This virus had a six-amino-acid deletion in the subgroup A hr1 that altered receptor usage. This approach may identify regions of SU that play a critical role in receptor specificity.  (+info)

TY - JOUR. T1 - Sequence-specific DNA binding by the v-erbA oncogene protein of avian erythroblastosis virus. AU - Bonde, Beverly Geary. AU - Privalsky, Martin L.. PY - 1990. Y1 - 1990. N2 - The v-erbA oncogene, a transduced copy of a thyroid hormone receptor, plays an important role in establishment of the transformed cell phenotype induced by avian erythroblastosis virus. The ability of thyroid hormone receptors to bind to specific sites on chromatin and to thereby modify the expression of adjacent target genes is a crucial element in their mechanism of action in the normal cell. The v-erbA protein also bound at high affinity to a set of DNA fragments recognized by the rat thyroid hormone receptor, but the relative affinity of the v-erbA protein for the different binding sites was distinct from that previously reported for the thyroid hormone receptors.. AB - The v-erbA oncogene, a transduced copy of a thyroid hormone receptor, plays an important role in establishment of the transformed cell ...
TY - JOUR. T1 - Proper processing of avian sarcoma/leukosis virus capsid proteins is required for infectivity. AU - Xiang, Y.. AU - Thorick, R.. AU - Vana, M. L.. AU - Craven, R.. AU - Leis, J.. N1 - Copyright: Copyright 2007 Elsevier B.V., All rights reserved.. PY - 2001. Y1 - 2001. N2 - The formation of the mature carboxyl terminus of CA in avian sarcoma/leukemia virus is the result of a sequence of cleavage events at three PR sites that lie between CA and NC in the Gag polyprotein. The initial cleavage forms the amino terminus of the NC protein and releases an immature CA, named CA1, with a spacer peptide at its carboxyl terminus. Cleavage of either 9 or 12 amino acids from the carboxyl terminus creates two mature CA species, named CA2 and CA3, that can be detected in avian sarcoma/leukemia virus (R. B. Pepinsky, I. A. Papayannopoulos, E. P. Chow, N. K. Krishna, R. C. Craven, and V. M. Vogt, J. Virol. 69:6430-6438, 1995). To study the importance of each of the three CA proteins, we introduced ...
TY - JOUR. T1 - Transmembrane domain of the AEV erb B oncogene protein is not required for partial manifestation of the transformed phenotype. AU - Bassiri, Mansour. AU - Privalsky, Martin L.. PY - 1987. Y1 - 1987. N2 - The transmembrane domain was deleted from within the v-erb B protein coding region of avian erythroblastosis virus. The mutant oncogene encoded a shortened, apparently soluble form of the normally membrane bound v-erb B protein. Despite this alteration in subcellular distribution, the mutant polypeptide retained the ability to induce fibroblast transformation by several parameters, including the ability to display anchorage-independent growth. It appears that the transmembrane domain, although important for full manifestation of the transformed phenotype, is not essential for v-erb B-mediated oncogenic transformation.. AB - The transmembrane domain was deleted from within the v-erb B protein coding region of avian erythroblastosis virus. The mutant oncogene encoded a shortened, ...
Looking for Erythroblastosis faetalis? Find out information about Erythroblastosis faetalis. a disease manifested at birth or shortly thereafter and generally caused by incompatibility of the mothers blood with that of the fetus with respect to the... Explanation of Erythroblastosis faetalis
ERG antibody, Internal (v-ets avian erythroblastosis virus E26 oncogene homolog) for WB. Anti-ERG pAb (GTX77743) is tested in Human samples. 100% Ab-Assurance.
Extravagant regulations of the erythroblastosis oncogene B (ErbB) family of receptor tyrosine kinases (RTKs) and their ligands is normally common in individual malignancies. fulvestrant, recommending ErbB3 since a focus on designed for breasts cancer tumor treatment hence. Launch Aberrant regulations of the erythroblastosis oncogene C (ErbB) family members of receptor tyrosine kinases (RTKs) and their ligands is normally common in individual malignancies (1C4). This assembled family members consists of 4 related associates, HER1/ErbB1/EGFR, HER2/ErbB2/Neu, HER3/ErbB3, and HER4/ErbB4. Except for ErbB3, which provides extremely vulnerable kinase activity, the ErbB RTKs display dimerization-induced tyrosine phosphorylation and catalytic account activation that outcomes in indication transduction to intracellular goals. ErbBs are capable to type homodimers as well as heterodimers with various other coreceptors of the ErbB family members. ErbB3 depends on transphosphorylation 131436-22-1 IC50 by ...
RecombinantHuman V-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (avian)protein, was expressed in Human HEK293 cells and purified by SDS-PAGE andCoomassie blue staining
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Looking for online definition of leukosis-sarcoma neoplastic diseases in the Medical Dictionary? leukosis-sarcoma neoplastic diseases explanation free. What is leukosis-sarcoma neoplastic diseases? Meaning of leukosis-sarcoma neoplastic diseases medical term. What does leukosis-sarcoma neoplastic diseases mean?
Hamster cells transformed with the Schmidt-Ruppin strain of avian sarcoma virus were selected for resistance to ethidium bromide (EB). The resistant cell lines proliferated in the presence of up to 30 µg/ml EB.. From avian sarcoma virus-transformed hamster cells already resistant to bromodeoxy-uridine (BrdU), ethidium bromide-resistant cells which were able to grow in 10 µg/ml EB were also prepared. These cells remain deficient in thymidine kinase activity and are suitable for selective preparation of hybrid cells.. The EB resistance was genetically stable. The EB-resistant cell lines, and doubly resistant cells (BrdU, EB) showed no differences in mitochondrial ultrastructure compared with the original cell lines. Thymidine incorporation into mitochondrial DNA was not influenced by EB resistance.. All resistant cell lines, including the doubly resistant cell line, contained the avian sarcoma virus genome. The number of cells needed for positive rescue experiments for avian sarcoma virus genome ...
The proto- oncogene c- erbB- 1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v- erbB which was isolated from an avian erythroblastosis virus ( AEV) where it was contained as a fragment of the chicken c- ErbB- 1 gene lacking the amino- terminal ligand- binding domain. Overexpression of erbB- 1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c- erbB- 1 gene is located in the chromosomal region 7p14 and 7p12 ...
Chicken erythroblasts transformed with avian erythroblastosis virus or S13 virus provide suitable model systems with which to analyze the maturation of immature erythroblasts into erythrocytes. The transformed cells are blocked in differentiation at around the colony-forming unit-erythroid stage of development but can be induced to differentiate in vitro. Analysis of the expression and assembly of components of the membrane skeleton indicates that these cells simultaneously synthesize alpha-spectrin, beta-spectrin, ankyrin, and protein 4.1 at levels that are comparable to those of mature erythroblasts. However, they do not express any detectable amounts of anion transporter. The peripheral membrane skeleton components assemble transiently and are subsequently rapidly catabolized, resulting in 20-40-fold lower steady-state levels than are found in maturing erythrocytes. Upon spontaneous or chemically induced terminal differentiation of these cells expression of the anion transporter is initiated ...
Compare E26 avian leukemia oncogene 2, 3 domain Biomolecules from leading suppliers on Biocompare. View specifications, prices, citations, reviews, and more.
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Vogt, P.K., Neil, J.C. , Moscovici, C. and Breitman, M.L. (1981) PRCII, a representative of a new class of avian sarcoma viruses. In: Neth, R., Gallo, R.C., Graf, T., Mannweiler, K. and Winkler, K. (eds.) Modern Trends in Human Leukemia IV. Series: Haematology and blood transfusion, 26. Springer, pp. 424-428. ISBN 9783540106227 (doi:10.1007/978-3-642-67984-1_77) ...
ETS1 (phospho Thr38) antibody (E26 avian leukemia oncogene 1, 5 domain) for ICC/IF, IHC-P, WB. Anti-ETS1 (phospho Thr38) pAb (GTX55307) is tested in Human, Mouse samples. 100% Ab-Assurance.
Looking for online definition of v-ets erythroblastosis virus E26 oncogene homolog 2 in the Medical Dictionary? v-ets erythroblastosis virus E26 oncogene homolog 2 explanation free. What is v-ets erythroblastosis virus E26 oncogene homolog 2? Meaning of v-ets erythroblastosis virus E26 oncogene homolog 2 medical term. What does v-ets erythroblastosis virus E26 oncogene homolog 2 mean?
Define erythroblastosis fetalis. erythroblastosis fetalis synonyms, erythroblastosis fetalis pronunciation, erythroblastosis fetalis translation, English dictionary definition of erythroblastosis fetalis. n. A severe hemolytic disease of a fetus or newborn infant caused by the production of maternal antibodies against the fetal red blood cells, usually...
Description of disease Erythroblastosis fetalis. Treatment Erythroblastosis fetalis. Symptoms and causes Erythroblastosis fetalis Prophylaxis Erythroblastosis fetalis
Avian sarcoma leukosis virus (ASLV) is an endogenous retrovirus that infects and can lead to cancer in chickens; experimentally it can infect other species of birds and mammals. ASLV replicates in chicken embryo fibroblasts, the cells that contribute to the formation of connective tissues. Lymphoid leukosis is the most common form of this disease and with typical presentation of gradual onset, persistent low mortality, and neoplasia of the bursa. Subgroups A, B, E and J are the major subgroups of avian leukosis virus (ALV) infecting chickens. ALV infection has become endemic in many countries and has a significant negative effect on the poultry industry.. ...
The sequence of the human epidermal growth factor (EGF) receptor shows great homology with the avian erythroblastosis virus v-erb B oncogene, raising the possibility that the receptor gene is identical to the c-erb B protooncogene. Human A431 epidermoid carcinoma cells, which have an unusually high number of EGF receptors, were examined to determine whether elevated EGF receptor levels correlate with gene amplification. Southern blots of genomic DNAs from A431 and other human cell lines were probed with either a v-erb B gene fragment or a human EGF receptor complementary DNA clone (pE7), previously isolated from an A431 complementary DNA library. When either probe was used to analyze Eco RI- or Hind III-generated DNA fragments, EGF receptor DNA sequences were amplified about 30-fold in A431. Differences in the banding pattern of A431 DNA fragments relative to normal fibroblast DNA indicate the occurrence of a rearrangement in the region of the receptor gene. Furthermore, A431 cells contain a ...
Four previously uncharacterized avian sarcoma viruses were screened and two of these, RPL30 and CTIO, were found to encode apparently novel oncogenes. Biologically active CTIO DNA was molecularly cloned and the nucleotide sequence was determined. The CTIO genome encodes a gag-fusion polypeptide of 47 kilodaltons, termed p47gag-crk. This protein contains blocks of sequence similarity to a noncatalytic, potentially regulatory region found in the nonreceptor tyrosine kinases, a phosphoinositide-specific phospholipase C, and the ras GTPase activator protein; no homology was found to any known catalytic domain. Potential roles for the homologous domains, termed SH2 and SH3, in normal signal transduction and in the biological activity of p47gag-crk are discussed. Biochemical data demonstrated that phosphotyrosine levels on at least three cellular proteins were greatly elevated in CTI0-infected cells, and that a tyrosine kinase activity was immunoprecipitated in association with p47gag-crk. A specific
At the first baby, there are no antibodies against Rh+, while birth, blood of the baby and the mother mixes and there are some antibodies produced, And those antibodies make the second baby die or born with some abnormalities. IgG can pass through placenta. Actually erythroblastosis fetalis can also be defined as the lysis of fetal RBCs by maternal IgGs ...
Erythroblastosis fetalis occurs due to Rh incompatibility between the mother and the fetus, resulting in severe anemia and sometimes death of the fetus.
Austin, John Holcombe, Erythroblastosis fetalis: Pathogenesis and prognosis. A study of clinical obstetrical data (1965). Yale Medicine Thesis Digital Library. 2367 ...
anti-V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) (pThr358), (AA 340-385) antibody (Cy5.5) ABIN752598 from antibodies-online
Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; ...
Homo sapiens epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (EGFR), transcript variant 4, mRNA. (H00001956-R16) - Products - Abnova
EPA757Hu61, Eukaryotic Epidermal Growth Factor Receptor (EGFR), 表皮生长因子受体(EGFR)真核蛋白, ErbB-1; ErbB1; ER1; ERB-B1; MENA; HER1; Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog,Avian; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 | 仅供体外研究使用,不用于临床诊断!请索取进口关税税单及报关单!
Its another beautiful day on the Old McDonald|farm, and having fed and watered the horses, cows, sheep, and other assorted barnyard animals, you decide...
Kwangsic Joo; Lizhu Yang; Kazushige Tsunoda; Mineo Kondo; Yu Fujinami; Gavin Arno; Toshihide Kurihara; Kazuo Tsubota; Takeshi Iwata; Xuan Zou; Hui Li; Yozo Miyake; Kyu Hyung Park; Kaoru Fujinami; Ruifang Sui; Se Joon ...
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Doç. Dr. Uğur Aydın kim olduğunu ve kısa biyografisi burada bulabilir, hangi hastanede çalıştığına bakıp hemen randevu oluşturabilirsiniz.
芸姬 的使用心得,包含:溫和低刺激,保濕,清爽,不油膩,滋潤,不致痘,感謝ur和薇姿提供試用的機會~~拿到的時候天氣已經變熱了,
Ranthambore has inspired adventurers for centuries, mostly due to its large tiger population. In 1973 Project Tiger was allotted 60 square miles which was later expanded to become Ranthambore National Park. The tiger population has greatly fluctuated since the 80s which has brought much controversy about how authorities have handled the park matters. Since the initial shock of the decline in tigers from 44 in 1982 to a mere 26 in 2005, the government has improved their efforts to increase the tiger population. The Indian government has given $153 million to tiger reserves across India to assist the forest guards in their daily efforts. The ever present threat of poaching, along with the competition for land is a constant struggle. However, these efforts have proven successful in Ranthambore, and the tiger population has increased to a debatable 47 today.. ...
hypothetical protein, transcription factor protein, A306_09622, anon-WO03040301.171, avian myelocytomatosis viral oncogene homolog, avian myelocytomatosis viral (v-myc) oncogene homolog, bHLHe39, bHLHe57, cellular myelocytomatosis oncogene, CG10798 gene product from transcript CG10798-RB, CG10798-PA, CG10798-PB, class E basic helix-loop-helix protein 39, cmyc, c-MYC, c-myc20, c-Myc-a, c-Myc-b, c-myc-like protein, c-myc proto-oncogene, diminuitive, diminutive, DM, dm/dMyc, Dmel_CG10798, dm/myc, d-myc, dMYC, dmyc1, EG:BACN5I9.1, EGK_19271, lethal (1) G0354, lethal (1) G0359, MDA_GLEAN10014535, mMyc, MRTL, Myc2, myc-a, myc-b, MYCC, Myc-PA, Myc-PB, myc proto-oncogene protein, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, N303_07797, N307_12984, N309_06569, Niard, Nird, oncoprotein myc, PAL_GLEAN10003365, Proto-oncogene c-Myc, RNCMYC, transcription factor Myc, transcription factor p64, TREES_T100017263, uncharacterized ...
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species ...
Proteins encoded by oncogenes such as v-fps/fes, v-src, v-yes, v-abl, and v-fgr are cytoplasmic protein tyrosine kinases which, unlike transmembrane receptors, are localized to the inside of the cell. These proteins possess two contiguous regions of sequence identity: a C-terminal catalytic domain of 260 residues with homology to other tyrosine-specific and serine-threonine-specific protein kinases, and a unique domain of approximately 100 residues which is located N terminal to the kinase region and is absent from kinases that span the plasma membrane. In-frame linker insertion mutations in Fujinami avian sarcoma virus which introduced dipeptide insertions into the most stringently conserved segment of this N-terminal domain in P130gag-fps impaired the ability of Fujinami avian sarcoma virus to transform rat-2 cells. The P130gag-fps proteins encoded by these transformation-defective mutants were deficient in protein-tyrosine kinase activity in rat cells. However v-fps polypeptides derived
A DNA fragment size variant for the growth hormone gene, Gh, has been identified among inbred strains of mice. The inbred strains SM/J and CAST/Ei carry the less frequent allele Ghb and 11 other strains carry the Gha allele. Segregation analysis of data from two crosses involving SM/J and NZB/BINJ and a cross involving BALB/cJ and CAST/Ei confirmed the assignment of Gh to mouse chromosome 11 and placed the locus 2.6 +/- 1.8 map units distal to Erba (avian erythroblastosis oncogene A), a position consistent with the assignment of the Gh locus to the q22-q24 region of chromosome 17 on the human map. Segregation analysis also refined the location of Sparc (secreted acidic cysteine-rich glycoprotein) on mouse chromosome 11 to a position 16.7 +/- 4.2 map units proximal to Evi-2 (ecotropic viral integration site 2).
The avian leukemia sarcoma virus S13 transforms chicken and Japanese quail embryo fibroblasts and chicken erythroid cells in tissue culture. S13-induced erythroid transformation requires culture conditions suitable for the growth of normal erythroid precursors (H. Beug and M. J. Hayman (1984), Cell 36, 963-972). S13-transformed erythroid colonies contain a high percentage of cells that differentiate in absence of erythropoietin. S13 is defective in pol and env functions but can code for a complete set of gag proteins. Nonproducer cell clones transformed by S13 release a noninfectious viral particle containing gag but no functional env or pol proteins. They also synthesize a transformation-specific protein of 155,000 molecular weight. This protein reacts with antibody to viral envelope glycoproteins and appears to represent onc as well as env sequences. The 155,000-molecular weight env-linked protein does not cross react immunologically with an antiserum against the v-erb A and v-erb B gene ...
Gene Information This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins such as apoptosis antigen Fas centromere protein C and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications including sumoylation phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq Nov 2008]. ...
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The product of both the viral and cellular myc genes has been implicated as being a primary mediator of events leading to cellular transformation. In addition,...
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BACKGROUND: The majority of prostate cancers harbor gene fusions of the 5-untranslated region of the androgen-regulated transmembrane protease serine 2 (TMPRSS2) promoter with erythroblast transformation-specific transcription factor family members. The common fusion between TMPRESS2 and v-ets erythroblastosis virus E26 oncogene homolog (avian) (ERG) is associated with a more aggressive clinical phenotype, implying the existence of a distinct subclass of prostate cancer defined by this fusion.. METHODS: We used complementary DNA-mediated annealing, selection, ligation, and extension to determine the expression profiles of 6144 transcriptionally informative genes in archived biopsy samples from 455 prostate cancer patients in the Swedish Watchful Waiting cohort (1987-1999) and the United States-based Physicians() Health Study cohort (1983-2003). A gene expression signature for prostate cancers with the TMPRSS2-ERG fusion was determined using partitioning and classification models and used in ...
Incidence of avian leukosis virus infection in broiler stocks and its effect on early growth.: Twenty-eight broiler breeder flocks were tested for avian leukosi
Induction of lymphomas in the bursa of Fabricius of chickens by replication competent, non-transforming avian retroviruses (Avian Leukosis Virus, ALV) is both an economically significant, naturally...
L. D. Hernandez, Peters, R. J., Delos, S. E., Young, J. A. T., Agard, D. A., and White, J. M., Activation of a retroviral membrane fusion protein: soluble receptor-induced liposome binding of the ALSV envelope glycoprotein, The Journal of cell biology, vol. 139, no. 6, pp. 1455-1464, 1997. ...
The line was derived from normal lung tissue from a child who died of erythroblastosis (Rh incompatibility). A normal skin line derived from the same patient is available as ATCC CRL-1497.
Edited by John M. Coffin, Tufts University School of Medicine, Boston, MA (received for review February 24, 2004) ArticleFigures SIInfo gt;5 kDa in size are required. Furthermore, later steps of avian sarcoma and leukosis virus reverse tran
Kaoru Fujinami; Shuhei Kameya; Sachiko Kikuchi; Shinji Ueno; Mineo Kondo; Takaaki Hayashi; Kei Shinoda; Shigeki Machida; Kazuki Kuniyoshi; Yuichi Kawamura; Masakazu Akahori; Kazutoshi Yoshitake; Satoshi Katagiri; Ayami Nakanishi; Hiroyuki Sakuramoto; Yoko Ozawa; Kazuo Tsubota; Kunihiko Yamaki; Atsushi Mizota; Hiroko Terasaki; Yozo Miyake; Takeshi Iwata; Kazushige ...
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@amistre64 PLZZ I NEED UR HELP!!name for reactants that are affected by enzymes. @SolomonZelman . Enzymes lower the activation energy, they increase ...
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1) Make sure the Power Button on the right front of the imager shows a green light. If not press it until the green light comes on and wait 5-10 min for warm up. 2) Open the UV transilluminator drawer on the lower front of the imager and make sure that the XcitaBlue Conversion Screen is in place. If not find it and position it covering the glass. Clean it with water and a paper towel if necessary. 3) Position your gel in the center of the glass. 4) Close the drawer, remove gloves, and wash your hands before using the computer to the left of the imager. 5) Open the ImageLab 4.0.1 software by double clicking on the icon on the computer desktop 6) Find and open the Protocol called SybrSafe under Recent Protocols or from the Open Menu. Double click to open it. 7) Click Position Gel (yellow button) to check the position of your gel. 8) Click Run Protocol (green button) to take the photo. 9) To Save your image (if you are not going to analyze it quantitatively), find or make a folder for your work in ...
Genus Alpharetrovirus; type species: Avian leukosis virus; others include Rous sarcoma virus ...
Genus Alpharetrovirus. *Genus Betaretrovirus. *Genus Gammaretrovirus. *Genus Deltaretrovirus. *Genus Epsilonretrovirus. *Genus ...
Retrovirus (retroviridae) er en gruppe af revers transskriberende RNA-virus. De bruger en revers transkriptase - et DNA polymerase-enzym - der i cellen oversætter retrovirusens enkeltstrengede RNA til dobbeltstrenget DNA. Dette DNA integreres i værtscellens eget DNA og danner så grundlaget for produktion af nye viruspartikler.[1] Der findes mange retrovirus, der inficerer dyr og mennesker, nogle af disse er oncogene: HTLV-1, og -2, samt HIV-1 og -2. HIV-1 (human immunodeficiency virus) er den bedst kendte, da den er årsagen til AIDS. ...
This family now includes the following genera: Subfamily Orthoretrovirinae: Genus Alpharetrovirus; type species: Avian leukosis ...
It is of the genus Alpharetrovirus, and has a C-type morphology. Hence, it is an enveloped virus with a condensed, central core ...
Alphapartitivirus Alphapermutotetravirus Alphapleolipovirus Alphapolyomavirus Alphaportoglobovirus Alpharetrovirus ...
... alpharetrovirus MeSH B04.820.650.070.250 - erythroblastosis virus, avian MeSH B04.820.650.070.500 - leukosis virus, avian MeSH ... alpharetrovirus MeSH B04.909.574.807.070.250 - erythroblastosis virus, avian MeSH B04.909.574.807.070.500 - leukosis virus, ... alpharetrovirus MeSH B04.909.777.731.070.250 - erythroblastosis virus, avian MeSH B04.909.777.731.070.500 - leukosis virus, ...
... at the US National Library of Medicine Medical Subject Headings (MeSH) ICTVdb Viralzone: Alpharetrovirus [1] v ... Alpharetrovirus is a genus of the family Retroviridae. It has type C morphology. Members can cause sarcomas, other tumors, and ...
Alpharetrovirus: , Alphaspiravirus: , Alphatetraviridae , Alphatorquevirus: , Alphaturrivirus: , Alphavirus: , Alvernaviridae ...
Alpharetrovirus. *Avian sarcoma leukosis virus. *Rous sarcoma virus. Betaretrovirus. *Mouse mammary tumor virus ...
Alpharetrovirus. *Avian sarcoma leukosis virus. *Rous sarcoma virus. Betaretrovirus. *Mouse mammary tumor virus ...
Alpharetrovirus. *Avian sarcoma leukosis virus. *Rous sarcoma virus. Betaretrovirus. *Mouse mammary tumor virus ...
ওয়ার্ল্ড হেলথ ওর্গানাইজেসন (WHO) (World Health Organization) মানবদেহে এইচ.আই.ভি ভাইরাসের সঙ্ক্রমনকে প্যান্ডেমিক (Pandemic) হিসাবে চিহ্নিত করেছে[৪][৫]। ১৯৮১ সালে ভাইরাসটি আবিষ্কারের পর থেকে ২০০৬ সাল পর্যন্ত এইডস রোগ কারণে ২কোটি ৫০ লক্ষেরও বেশি মানুষ মারা যায়।[৬] পৃথিবীর মোট জনসংখ্যার প্রায় ০.৬% এই ভাইরাস দ্বারা আক্রান্ত[৬]। ২০০৫ সালে এইডস ২২ থেকে ৩৩ লক্ষ মানুষের জীবন কেড়ে নেয় যার মধ্যে ৫ লক্ষ ৭০ হাজারের ও ...
Alpharetrovirus at the US National Library of Medicine Medical Subject Headings (MeSH) ICTVdb Viralzone: Alpharetrovirus [1] v ... Alpharetrovirus is a genus of the family Retroviridae. It has type C morphology. Members can cause sarcomas, other tumors, and ...
Genus Alpharetrovirus; type species: Avian leukosis virus; others include Rous sarcoma virus ...
Genus Alpharetrovirus. *Genus Betaretrovirus. *Genus Gammaretrovirus. *Genus Deltaretrovirus. *Genus Epsilonretrovirus. *Genus ...
Alpha-retrovirus. genome ,8kb; assembly at cell membrane. avian leukosis virus. birds. malignancies. ...
Alpharetrovirus. Genus. Betaretrovirus. Genus. Gammaretrovirus. Genus. Deltaretrovirus. Genus. Epsilonretrovirus. Genus. ...
Retrovirus (retroviridae) er en gruppe af revers transskriberende RNA-virus. De bruger en revers transkriptase - et DNA polymerase-enzym - der i cellen oversætter retrovirusens enkeltstrengede RNA til dobbeltstrenget DNA. Dette DNA integreres i værtscellens eget DNA og danner så grundlaget for produktion af nye viruspartikler.[1] Der findes mange retrovirus, der inficerer dyr og mennesker, nogle af disse er oncogene: HTLV-1, og -2, samt HIV-1 og -2. HIV-1 (human immunodeficiency virus) er den bedst kendte, da den er årsagen til AIDS. ...
Genus: Alpharetrovirus Species: Avian carcinoma Mill Hill virus 2 Name[edit]. Avian carcinoma Mill Hill virus 2 ...
Alpharetrovirus. Betaretrovirus. Gammaretrovirus. Deltaretrovirus. Epsilonretrovirus. Lentivirus. Subfamily: Spumaretrovirinae ... Alpharetrovirus (Avian leukosis virus, Rous sarcoma virus) - Betaretrovirus (Mouse mammary tumour virus) - Gammaretrovirus ( ...
Alpharetrovirus. Betaretrovirus. Gammaretrovirus. Deltaretrovirus. Epsilonretrovirus. Lentivirus. Subfamily: Spumaretrovirinae ... Genus Alpharetrovirus; type species: Avian leukosis virus; others include Rous sarcoma virus ...
This family now includes the following genera: Subfamily Orthoretrovirinae: Genus Alpharetrovirus; type species: Avian leukosis ...
Avian leukosis virus (ALV) belongs to the genus Alpharetrovirus of the Retroviridae family. This virus is capable of inducing ...
Importin beta family members mediate alpharetrovirus Gag nuclear entry via interactions with MA and NC. J. Virol. 80, 1798-1806 ... and an alpharetrovirus (RSV), betaretrovirus (MPMV), gammaretrovirus (MLV), and deltaretrovirus (HTLV-2) are depicted. In each ...
Avian carcinoma Mill Hill virus 2 (ACMHV-2) - Alpharetrovirus. *M14008 Recombinant avian retrovirus MH2E21, complete genome. ... Avian myeloblastosis virus (AMV) - Alpharetrovirus. *AF033809 Avian myelocytomatosis virus, complete genome.. Avian ... Avian sarcoma virus CT10 (ASV-CT10) - Alpharetrovirus. *M10455 UR2 sarcoma virus, complete genome. ... Avian leukosis virus (ALV) - Alpharetrovirus. *M37980 Avian leukemia virus ALV-RSA genome. ...
The single cell reproductive cycle of the alpharetrovirus, ALV. The virus life cycle is divided into an early phase that ... The single cell reproductive cycle of the alpharetrovirus, ALV. The virus life cycle is divided into an early phase that ...
Importin-beta family members mediate alpharetrovirus gag nuclear entry via interactions with matrix and nucleocapsid. J Virol ...
Importin-β family members mediate alpharetrovirus Gag nuclear entry via interactions with matrix and nucleocapsid. J. Virol.80: ...
In chickens, an immunological assay for Gag antigen was used to screen flocks to determine whether they harboured the alpha-retrovirus ... This finding indicated that the alpha-retrovirus endogenous sequences had colonized the germ-line very recently in evolution, ...
Committee on Taxonomy of Viruses has designated avian leukosis virus as the type species within the Alpharetrovirus genus of ...
Alpharetrovirus (Avian leukosis virus, Rous sarcoma virus) - Betaretrovirus (Mouse mammary tumour virus) - Gammaretrovirus ( ...
Achenbach, J. D. & Qu, J., Dec 1 1986, Review of Progress in Quantitative Nondestructive Evaluation. Thompson, D. O. & Chimenti, D. E. (eds.). Plenum Press, Vol. 5 B. p. 1179-1188 10 p.. Research output: Chapter in Book/Report/Conference proceeding › Conference contribution ...
... and Alpharetrovirus/Betaretrovirus-related (AB). Placeholder groups are reserved for ERVs that do not group within the ... and Alpharetrovirus/Betaretrovirus-related (AB). Placeholder groups (indicated by coloured squares) are reserved for ERVs that ...
Here, we characterize five previously unstudied integrase proteins, including those derived from the alpharetrovirus ...
Alpharetrovirus: , Alphaspiravirus: , Alphatetraviridae , Alphatorquevirus: , Alphaturrivirus: , Alphavirus: , Alvernaviridae ...
Alpharetrovirus Betaretrovirus Gammaretrovirus Deltaretrovirus Epsilonretrovirus Lentivirus Spumavirus A retrovirus is a virus ...
Alpharetrovirus , Avian leukosis virus; Rous sarcoma virus, Betaretrovirus , Mouse mammary tumor virus, Gammaretrovirus, Murine ...
else case ,OC:Alpharetrovirus, and ,Feature:PS50879,. Function. RT is a multifunctional enzyme that converts the viral dimeric ...
Genus Alpharetrovirus (organism) {407403006 , SNOMED-CT } Other Relationships No other relationships present. ...
RSV Alpharetrovirus XC, rat cell line, - transformed with RSV (CCL/NBRL) MSV Alpharetrovirus F81, cat cell line, MSV - - ...
Barnard RJ, Young JA: Alpharetrovirus envelope-receptor interactions. Curr Top Microbiol Immunol. 2003, 281: 107-136. ...
The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS ...
  • The International Committee on Taxonomy of Viruses has designated avian leukosis virus as the type species within the Alpharetrovirus genus of the family Retroviridae . (merckvetmanual.com)
  • Alpharetrovirus is a genus of the family Retroviridae. (wikipedia.org)
  • Retrovirus ( retroviridae ) er en gruppe af revers transskriberende RNA - virus . (wikipedia.org)
  • These platforms can be used to monitor clonal dynamics in individual subjects over time, across multiple subjects and species treated with the same vectors or across different vector types including gammaretrovirus, lentivirus, foamy virus and alpharetrovirus vectors to compare patterns of genomic integration. (fhcrc.org)