Macropodid herpesviruses 1 and 2 occupy unexpected molecular phylogenic positions within the Alphaherpesvirinae. (1/106)

The molecular phylogeny of macropodid herpesviruses 1 and 2 (MaHV-1 and -2) has been investigated by cloning and sequencing the genes encoding glycoprotein B from both viruses. Phylogenetic reconstructions based on the putative amino acid sequences of glycoprotein B indicate that MaHV-1 and -2 are most closely related to the subfamily Alphaherpesvirinae. Within the Alphaherpesvirinae, MaHV-1 and -2 are closely associated with those herpesviruses that infect primates. This phylogenetic relationship does not fit the constraints of the proposed co-evolution theory described for other members of the Alphaherpesvirinae which have mammalian hosts.  (+info)

Cellular elongation factor 1delta is modified in cells infected with representative alpha-, beta-, or gammaherpesviruses. (2/106)

Earlier reports (Y. Kawaguchi, R. Bruni, and B. Roizman, J. Virol. 71:1019-1024, 1997; Y. Kawaguchi, C. Van Sant, and B. Roizman, J. Virol. 72:1731-1736, 1998) showed that herpes simplex virus 1 (HSV-1) infection causes the hyperphosphorylation of translation elongation factor 1delta (EF-1delta) and that the modification of EF-1delta is the consequence of direct phosphorylation by a viral protein kinase encoded by the UL13 gene of HSV-1. The UL13 gene is conserved in members of all herpesvirus subfamilies. Here we report the following. (i) In various mammalian cells, accumulation of the hyperphosphorylated form of EF-1delta is observed after infection with alpha-, beta-, and gammaherpesviruses, including HSV-2, feline herpesvirus 1, pseudorabiesvirus, bovine herpesvirus 1, human cytomegalovirus (HCMV), and equine herpesvirus 2. (ii) In human lung fibroblast cells infected with recombinant HSV-1 lacking the UL13 gene, the hypophosphorylated form of EF-1delta is a minor species, whereas the amount of the hyperphosphorylated form of EF-1delta significantly increases in cells infected with the recombinant HSV-1 in which UL13 had been replaced by HCMV UL97, a homologue of UL13. These results indicate that the posttranslational modification of EF-1delta is conserved herpesvirus function and the UL13 homologues may be responsible for the universal modification of the translation factor.  (+info)

Studies of genetic relationships between bovine, caprine, cervine, and rangiferine alphaherpesviruses and improved molecular methods for virus detection and identification. (3/106)

The glycoprotein B (gB) and D (gD) genes from five ruminant alphaherpesviruses, bovine herpesvirus 1 (BHV-1), bovine herpesvirus 5 (BHV-5), caprine herpesvirus 1 (CapHV-1), cervine herpesvirus 1, and rangiferine herpesvirus 1, were partially sequenced. The nucleotide sequence alignments revealed a highly conserved gB gene, with homologies ranging between 87.2 and 99.6%, and a more variable gD gene, with homologies ranging between 71.3 and 98.9%. The phylogenetic analysis of the gB and gD nucleotide and deduced amino acid sequences revealed that BHV-5 is the most closely related virus to the BHV-1 subtype 1 and BHV-1 subtype 2 cluster and that CapHV-1 is the most distantly related virus. The phylogenetic data showed a close relationship of all the studied viruses with suid herpesvirus 1. On the basis of sequence data for the gB gene, a nested PCR combined with restriction enzyme analysis (REA) of the PCR products was developed for the simultaneous detection and identification of the viruses that were studied. Nested primers from highly conserved sequence stretches were selected in order to amplify a region of 294 bp in all five viruses, and a subsequent REA of the PCR products allowed specific identification. A mimic molecule that served as an internal standard of the amplification efficiency was constructed. The practical diagnostic applicability of the assay was evaluated with clinical samples consisting of semen and organ specimens from experimentally infected animals.  (+info)

Complementation of a gl-deficient feline herpesvirus recombinant by allotopic expression of truncated gl derivatives. (4/106)

The alphaherpesvirus glycoproteins gE and gI form a hetero-oligomeric complex involved in cell-to-cell transmission. The gI-deficient recombinant feline herpesvirus (FHV), FHVdeltagI-LZ, produces plaques that are only 15% the size of those of wild-type FHV. Here, we have complemented FHV(delta)gI-LZ allotopically by expressing intact gI and C-terminally truncated gI derivatives from the thymidine kinase locus. The effect on gE-gI-mediated cell-to-cell spread was assessed by plaque assay employing computer-assisted image analysis (software available at http://www.androclus.vet.uu.nl/spotter/spotter.htm+ ++). Allotopic complementation with intact gI fully restored plaque size. Deletion of the C-terminal 11 residues of gI did not affect cell-to-cell spread, whereas deletion of the complete cytoplasmic tail reduced plaque size by only 35%. Mutants expressing gI166, roughly corresponding to the N-terminal half of the ectodomain, displayed a small-plaque phenotype. Nevertheless, their plaques were reproducibly larger than those of matched gI-deficient controls, indicating that the gE-gI166 hetero-oligomer, though crippled, is still able to mediate cell-to-cell spread. Our data demonstrate that plaque analysis provides a reliable and convenient tool to measure and quantitate gE-gI function in vitro.  (+info)

Mutations in the conserved carboxy-terminal hydrophobic region of glycoprotein gB affect infectivity of herpes simplex virus. (5/106)

Glycoprotein gB is the most highly conserved glycoprotein in the herpesvirus family and plays a critical role in virus entry and fusion. Glycoprotein gB of herpes simplex virus type 1 contains a hydrophobic stretch of 69 aa near the carboxy terminus that is essential for its biological activity. To determine the role(s) of specific amino acids in the carboxy-terminal hydrophobic region, a number of amino acids were mutagenized that are highly conserved in this region within the gB homologues of the family HERPESVIRIDAE: Three conserved residues in the membrane anchor domain, namely A786, A790 and A791, as well as amino acids G743, G746, G766, G770 and P774, that are non-variant in Herpesviridae, were mutagenized. The ability of the mutant proteins to rescue the infectivity of the gB-null virus, K082, in trans was measured by a complementation assay. All of the mutant proteins formed dimers and were incorporated in virion particles produced in the complementation assay. Mutants G746N, G766N, F770S and P774L showed negligible complementation of K082, whereas mutant G743R showed a reduced activity. Virion particles containing these four mutant glycoproteins also showed a markedly reduced rate of entry compared to the wild-type. The results suggest that non-variant residues in the carboxy-terminal hydrophobic region of the gB protein may be important in virus infectivity.  (+info)

Identification and characterization of bovine herpesvirus type 5 glycoprotein H gene and gene products. (6/106)

Bovine herpesvirus type 5 (BHV-5) is the causative agent of a fatal meningo-encephalitis in calves and is closely related to BHV-1 which causes infectious bovine rhinotracheitis. The gene encoding BHV-5 glycoprotein gH was sequenced. A high degree of conservation was found between BHV-1 and BHV-5 deduced gH amino acid sequences (86. 4%), which is also observed for all alphaherpesvirus gH sequences. Transcriptional analysis revealed a 3.1 kb mRNA as the specific gH transcript which was detected 2 h post-infection (p.i.). Twelve out of twenty-one MAbs directed against BHV-1 gH immunoprecipitated a 108-110 kDa glycoprotein, which was then designated BHV-5 gH. Synthesis and intracellular processing of BHV- 5 gH was analysed in infected MDBK cells using gH cross-reacting MAbs. Glycoprotein gH was expressed as a beta-gamma protein, detected by radioimmunoprecipitation as early as 3 h p.i. Glycosylation studies indicated that BHV-5 gH contains N-linked carbohydrates which are essential for the recognition of the protein by the MAbs. This suggests that N-linked glycans are involved in protein folding or are targets for the gH cross-reacting MAbs. Plaque- reduction neutralization assays showed that at least one BHV-1 gH antigenic domain is lacking in BHV-5 which may possibly relate to in vivo differences in virus tropism.  (+info)

Bovine herpesvirus 5 glycoprotein E is important for neuroinvasiveness and neurovirulence in the olfactory pathway of the rabbit. (7/106)

Glycoprotein E (gE) is important for full virulence potential of the alphaherpesviruses in both natural and laboratory hosts. The gE sequence of the neurovirulent bovine herpesvirus 5 (BHV-5) was determined and compared with that of the nonneurovirulent BHV-1. Alignment of the predicted amino acid sequences of BHV-1 and BHV-5 gE open reading frames showed that they had 72% identity and 77% similarity. To determine the role of gE in the differential neuropathogenesis of BHV-1 and BHV-5, we have constructed BHV-1 and BHV-5 recombinants: gE-deleted BHV-5 (BHV-5gEDelta), BHV-5 expressing BHV-1 gE (BHV-5gE1), and BHV-1 expressing BHV-5 gE (BHV-1gE5). Neurovirulence properties of these recombinant viruses were analyzed using a rabbit seizure model (S. I. Chowdhury et al., J. Comp. Pathol. 117:295-310, 1997) that distinguished wild-type BHV-1 and -5 based on their differential neuropathogenesis. Intranasal inoculation of BHV-5 gEDelta and BHV-5gE1 produced significantly reduced neurological signs that affected only 10% of the infected rabbits. The recombinant BHV-1gE5 did not invade the central nervous system (CNS). Virus isolation and immunohistochemistry data suggest that these recombinants replicate and spread significantly less efficiently in the brain than BHV-5 gE revertant or wild-type BHV-5, which produced severe neurological signs in 70 to 80% rabbits. Taken together, the results of neurological signs, brain lesions, virus isolation, and immunohistochemistry indicate that BHV-5 gE is important for efficient neural spread and neurovirulence within the CNS and could not be replaced by BHV-1 gE. However, BHV-5 gE is not required for initial viral entry into olfactory pathway.  (+info)

Cellular expression of alphaherpesvirus gD interferes with entry of homologous and heterologous alphaherpesviruses by blocking access to a shared gD receptor. (8/106)

Several human and animal alphaherpesviruses can enter cells via human herpesvirus entry mediator C (HveC), a receptor for viral glycoprotein D (gD). In previous studies with cells expressing unknown entry mediators, cellular expression of alphaherpesvirus gD was shown to inhibit entry of the homologous virus and sometimes also of heterologous alphaherpesviruses. To investigate the mechanism of gD-mediated interference and the basis for cross-interference among alphaherpesviruses, HveC was expressed in cells as the sole entry mediator, in the presence or absence of one of the gDs encoded by herpes simplex virus type 1, pseudorabies virus, or bovine herpesvirus type 1. Cells expressing HveC alone were highly susceptible to entry of all three viruses, whereas cells coexpressing HveC and any one of the gDs were at least partially resistant to infection by each virus. Coexpression of gD with HveC did not cause reduced levels of cell-surface HveC but the HveC had reduced ability to bind to exogenous gD. Coimmunoprecipitation experiments revealed that HveC was complexed with gD in lysates of cells expressing both. Thus, cellular expression of gD can interfere with alphaherpesvirus entry by blocking ligand-binding sites of the gD receptor(s) used for entry and cross-interference can occur because different forms of alphaherpesvirus gD can compete for shared entry receptors.  (+info)

*Alphaherpesvirinae

... at the US National Library of Medicine Medical Subject Headings (MeSH) Viralzone: Alphaherpesvirinae ICTV ... Alphaherpesvirinae is a subfamily of Herpesviridae, primarily distinguished by reproducing more quickly than other subfamilies ... In animal virology the most important herpesviruses belong to the Alphaherpesvirinae. Pseudorabies virus is the causative agent ... Group: dsDNA Order: Herpesvirales Family: Herpesviridae Sub-Family: Alphaherpesvirinae Genus: Iltovirus Gallid herpesvirus 1 ...

*Herpesviridae

Subfamily Alphaherpesvirinae Genus Simplexvirus Ateline herpesvirus 1, spider monkey herpesvirus. Bovine herpesvirus 2 causes ... These are zoonotic infections: In animal virology, the best known herpesviruses belong to the subfamily Alphaherpesvirinae. ... Group: dsDNA Order: Herpesvirales Family: Herpesviridae Sub-Family: Alphaherpesvirinae Genus: Iltovirus Gallid herpesvirus 1 ... In this report the family Herpesviridae was divided into 3 subfamilies (Alphaherpesvirinae, Betaherpesvirinae and ...

*Varicella zoster virus

McGeoch DJ, Cook S (1994). "Molecular phylogeny of the alphaherpesvirinae subfamily and a proposed evolutionary timescale". J ...

*DNA virus

The alphaherpesvirinae separated from the branch leading to the betaherpesvirinae and gammaherpesvirinae about 180 million ... McGeoch DJ, Cook S (1994). "Molecular phylogeny of the alphaherpesvirinae subfamily and a proposed evolutionary timescale". J ...

*Duck plague

Anatid herpesvirus 1 is under the Herpesvirales order, the Herpesviridae family, the Alphaherpesvirinae subfamily. The genus ...

*Bovine herpesvirus 5

... is a virus species of the Varicellovirus genus and Alphaherpesvirinae subfamily. It causes ...

*Mardivirus

The stages of replication are similar to other viruses in Alphaherpesvirinae, but there are a few differences. After the virus ... Mardivirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. ... Group: dsDNA Order: Herpesvirales Family: Herpesviridae Sub-Family: Alphaherpesvirinae Genus: Mardivirus Anatid herpesvirus 1 ...

*Simplexvirus

... is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae ... Group: dsDNA Order: Herpesvirales Family: Herpesviridae Sub-Family: Alphaherpesvirinae Genus: Simplexvirus Ateline herpesvirus ...

*Scutavirus

... is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. ... Group: dsDNA Order: Herpesvirales Family: Herpesviridae Sub-Family: Alphaherpesvirinae Genus: Scutavirus Chelonid herpesvirus 5 ...

*Iltovirus

... is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. ... Group: dsDNA Order: Herpesvirales Family: Herpesviridae Sub-Family: Alphaherpesvirinae Genus: Iltovirus Gallid herpesvirus 1 ...

*Human herpesvirus 6

In this report, the family Herpesviridae was divided into 3 subfamilies (alphaherpesvirinae, betaherpesvirinae and ...

*Varicellovirus

... (var′i-sel′ō-vi′rŭs) is a genus of viruses belonging to subfamily Alphaherpesvirinae, a member of family ...

*HHV Infected Cell Polypeptide 0

Simian varicella virus (SVV) is a varicellovirus that, like HSV-1 and HSV-2, belongs to the alphaherpesvirinae subfamily of ...

*Public health genomics

However, infection with human herpes simplex virus type-1, a member of the alphaherpesvirinae subfamily, did not provide ...

*Herpesvirales

In this report the family Herpesviridae was divided into 3 subfamilies (Alphaherpesvirinae, Betaherpesvirinae and ...

*Betaherpesvirinae

This is different from Alphaherpesvirinae, which establish latency in neurons, and Gammaherpesvirinae, which establish latency ...

*Virus

... subfamily Alphaherpesvirinae, and genus Varicellovirus. VZV is in Group I of the Baltimore Classification because it is a dsDNA ...

*Aladár Aujeszky

... is caused by a virus with icosahedral symmetry and belongs to the subfamily Alphaherpesvirinae within the family Herpesviridae ...

*Gammaherpesvirinae

... namely Alphaherpesvirinae, Betaherpesvirinae and Gammaherpesvirinae. Gammaherpesviruses belong to four separate genera: the ...

*Taxonomic list of viruses

Alphaherpesvirinae Genus: Iltovirus Gallid herpesvirus 1 Psittacid herpesvirus 1 Genus: Mardivirus Anatid herpesvirus 1 ...

*Bovine herpesvirus

... 1 of subfamily Alphaherpesvirinae and genus Varicellovirus Bovine herpesvirus 2 of subfamily ... Alphaherpesvirinae and genus Simplexvirus Bovine herpesvirus 3 Bovine herpesvirus 4 of subfamily Gammaherpesvirinae and genus ... Rhadinovirus Bovine herpesvirus 5 of subfamily Alphaherpesvirinae and genus Varicellovirus Bovine herpesvirus 6 of subfamily ...

*List of MeSH codes (B04)

... alphaherpesvirinae MeSH B04.909.204.382.100.374 --- infectious laryngotracheitis-like viruses MeSH B04.909.204.382.100.374.450 ... alphaherpesvirinae MeSH B04.280.382.100.374 --- infectious laryngotracheitis-like viruses MeSH B04.280.382.100.374.450 --- ...

*Equine herpesvirus

... 1 of the subfamily Alphaherpesvirinae and genus Varicellovirus Equine herpesvirus 2 of the subfamily ... 3 of the subfamily Alphaherpesvirinae and genus Varicellovirus Equine herpesvirus 4 of the subfamily Alphaherpesvirinae and ... 8 of the subfamily Alphaherpesvirinae and genus Varicellovirus Equine herpesvirus 9 of the subfamily Alphaherpesvirinae and ... 5 of the subfamily Gammaherpesvirinae and genus Rhadinovirus Equine herpesvirus 6 of the subfamily Alphaherpesvirinae and genus ...

*Cytomegalovirus

It is related to other herpesviruses within the subfamilies of Alphaherpesvirinae that includes herpes simplex viruses (HSV)-1 ...

*HHV Latency Associated Transcript

Simian varicella virus (SVV) is a Varicellovirus (a Genus of Subfamily Alphaherpesvirinae) which expresses an HHV LAT homolog ...
in Archives of Virology (2014), 159. Herpesviruses have mainly co-evolved with their hosts for millions of years. However, bovine herpesvirus 1 (BoHV1) and related ruminant alphaherpesviruses have been reported to cross the species barrier ... [more ▼]. Herpesviruses have mainly co-evolved with their hosts for millions of years. However, bovine herpesvirus 1 (BoHV1) and related ruminant alphaherpesviruses have been reported to cross the species barrier. Bubaline herpesvirus 1 (BuHV1) is an alphaherpesvirus closely related to BoHV1 and BoHV5. According to the serological cross-relationships between ruminant alphaherpesviruses, several surveys have studied the occurrence of BoHV1-related virus infection in wild and domestic ruminant species. Recent studies in Argentina showed an increase in serological prevalence against BoHV1 related viruses in water buffaloes (Bubalus bubalis) population. The aim of this study was to investigate the presence of related ruminant alphaherpesvirus in the ...
Looking for Feline herpesvirus? Find out information about Feline herpesvirus. of, relating to, or belonging to the Felidae , a family of predatory mammals, including cats, lions, leopards, and cheetahs, typically having a round head... Explanation of Feline herpesvirus
Previous work with HSV and the related alphaherpesviruses PrV and varicella-zoster virus has clearly demonstrated that gE-gI mediates or facilitates cell-to-cell spread, especially in solid tissues such as epithelium, in the nervous system, and with certain cultured cells, e.g., normal fibroblasts, epithelial cells, and neurons, cells that form extensive cell junctions (2, 24, 25). Other HSV glycoproteins function similarly in cell-to-cell spread, but unlike these glycoproteins, gE-gI functions in cell-to-cell spread but not in the entry of extracellular virions. Therefore, interactions between gE-gI and cell junctions may provide molecular details of how a herpesvirus moves directly from cell to cell.. When gE-gI was expressed in HEC-1A cells or in other epithelial cells by recombinant Ad vectors, the protein accumulated specifically along the lateral surfaces of cells and was not found on either the apical or basal surfaces or at tight junctions. Sorting of gE-gI to the basolateral surfaces of ...
Enquist LW, Scherer J. Alphaherpesviruses: parasites of theperipheral nervous system. Future Virology [Internet]. 2017;12 (10) :555-559.
Indirect immunofluorescence staining of MDBK cells infected with either BoHV-1, BoHV-5, CpHV-1, CvHV-1, CvHV-2, or the Anlier isolate. Cells were incubated unti
List of all the English words with 18 letters containing letter V. alphabaculoviruses, alphacoronaviruses, alphaherpesviruses, alumoklyuchevskite, anarcho-primitivism, anarchoprimitivism, anarcho-primitivist, anhydrovinblastine, anthroconservatism
Herpes B virus (BV) is a member of genus Simplexvirus within the Alphaherpesvirinae subfamily. It has also been known as Cercopithecine herpes virus 1, monkey B virus, B virus or Herpes B Monkey virus [1]. BV naturally infects macaque monkeys and generally causes only mild localized or asymptomatic infections [2]. When transmitted to foreign hosts, such as humans or monkey species other than macaques, B virus often results in severe pathogenesis, including paralysis, encephalitis, encephalomyelitis, and death [3-5]. Historically, BV has a fatality rate greater than 70% in untreated human BV infection cases [6].. Because of the high mortality of its infection in untreated humans and the lack of vaccines, BV is classified as a biosafety level 4 (BSL-4) pathogen [7, 8]. Owing to the biosafety concerns, little research has been conducted directly using BV; most of the knowledge on this virus is extrapolated from study of its closely related viral species of the subfamily Alphaherpesvirinae, herpes ...
PATEL, J R e DIDLICK, S. Epidemiology, disease and control of infections in ruminants by herpesviruses - An overview. J. S. Afr. Vet. Assoc. [online]. 2008, vol.79, n.1, pp.8-14. ISSN 2224-9435.. There are at least 16 recognised herpesviruses that naturally infect cattle, sheep, goats and various species of deer and antelopes. Six of the viruses are recognised as distinct alphaherpesviruses and 9 as gammaherpesviruses. Buffalo herpesvirus (BflHV) and ovine herpesvirus-1 (OvHV-1) remain officially unclassified. The prevalence of ruminant herpesviruses varies from worldwide to geographically restricted in distribution. Viruses in both subfamilies Alphaherpesvirinae and Gammaherpesvirinae cause mild to moderate and severe disease in respective natural or secondary ruminant hosts. Accordingly, the economic and ecological impact of the viruses is also variable. The molecular characteristics of some members have been investigated in detail. This has led to the identification of virulence-associated ...
Severe tracheitis and bronchitis were identified in two fatal cases of respiratory disease affecting a flock of Gouldian finches (Erythrura [Chloebia] gouldiae). Intranuclear inclusion bodies in epithelial cells of the upper respiratory tract were identified in samples from two birds. Electron microscopic examination showed that the inclusions consisted of viral particles consistent in appearance with Herpesviridae. Degenerate PCR primers targeting a conserved region of the herpesviral-DNA-dependent DNA polymerase were used to amplify a region of DNA isolated from tissues with lesions from each animal. Nucleotide sequencing of the PCR products yielded identical viral sequences that were distinct from known herpesviruses. An analysis of sequence homology indicated that these gene segments appear to belong to a member of the subfamily Alphaherpesvirinae.
American Journal of Veterinary ResearchJanuary 2009, Vol. 70, No. 1, Pages 99-104Assessment of viremia associated with experimental primary feline herpesvirus infection or presumed herpetic recrudescence in catsHans D. Westermeyer, DVM, Sara M. Thomasy, DVM, PhD, Helen Kado-Fong, MS, David J. Maggs, BVScObjective-To detect feline herpesvirus type 1 (FHV-1) in blood of cats undergoing experimental primary…
ICP4 is an important factor regulating the life cycle of HSV1. This conserved protein has several molecular functions, including activation of expression of viral late gene transcripts and inhibition of immediate early genes. Although ICP4 and its Alphaherpesvirinae homologs (eg.: IE62 of VZV) have been subjects of various molecular studies, a complete view of their molecular function is lacking. Here we present the results of fold recognition and molecular modelling of ICP4 functional domains. The performed state-of-the-art bioinformatic fold recognition analysis identified a dual helix-turn-helix motif as a binding module of repressor activities (so called region 2 domain). The mapping of distant homology identified that a segment responsible for activation of late gene promoters (region 4) exhibits folding of uracil DNA glycosylase (UDG), but seems to be a non-functional homolog of UDG. Potential implications of the results are discussed ...
Elsa always had runny eyes. The two-year-old cat had been rescued as a kitten by Penn Vet student Jennifer Bortree. Elsa was treated at the time for feline herpesvirus (FHV-1), one of the most common causes of upper respiratory infections in cats. Among other symptoms, FHV-1 infection often impacts the eyes.. ...
Unlike Tamox ifen scans, 0. 30 dB, and gain of the short arm of chromosome 12, and addi- tionally a restricted high level amplification. It gives a reliable, reproducible, and objective assessment of anal sphincter function. (1999) Prevalence of feline Chlamydia psittaci and feline herpesvirus 1 in cats with tamoxiffen respiratory tract disease.
Research data were analyzed by Pearson Correlation Coefficient, and stepwise regression procedures. Does the use of antibiotics in food-producing animals contribute to the problem? The diagnosis of Pachecos disease was based on the finding of characteristic histologic lesions and in many cases on the detection of herpesvirus virions by electron microscopy or the detection of herpesvirus-infected cells in impression smears of spleen or liver by use of a fluorescent antibody conjugate prepared against a PsHV isolated from a bird with Pachecos disease. Regular monitoring for treatment-emergent PN, sensible detection and intervention are relevant to prevent the development of more severe PN (Table 3).74,78 The NCI CTC definition of PN is commonly used in clinical routine, but should be used with neuropathy-specific patient-completed questionnaires, such as the whole or the reduced Total Neuropathy Score (Table 4).79 However, a need remains for more sensitive assessment tools that focus on MM ...
Canine Herpesvirus are one of two sexually transmitted diseases that affect unborn puppies. There are minimal symptoms, so its important for breeders to have their dogs tested prior to breeding. During pregnancy, keep the pregnant female away from other dogs until the puppies are a few weeks old. If a female is exposed at any time during pregnancy or for three weeks following the birth, the puppies are at risk. Puppies die from Canine Herpesvirus if the mother contracts the virus during or after pregnancy. The virus incubates in as little as three days causing breathing changes, loss of appetite and vomiting. Most puppies die within two days, and after three weeks of age, their bodies are able to battle the virus effectively. The canine STD is sexually transmitted, but it also spreads through mucus in the mouth and nose. Biting, licking and sniffing are additional ways the canine sexually transmitted disease spreads. If your dog has Canine Herpesvirus or youve lost puppies to the disease, it ...
matrin 3 an acidic protein that is a component of the nuclear matrix. May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Note: This description may include information from UniProtKB ...
The feline herpesvirus (FHV) is responsible for nasty respiratory infections in cats, and the disease can become chronic just like its human-specific counterpart. You arent at any risk of ...
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Reindeer are way more profound than Santas sleigh-pullers! Theyve been fascinating humans since prehistory! Learn more about rich symbolic reindeer meaning here.
Episode Guide for L.A. Law 1x12: Sidney, the Dead-Nosed Reindeer. Episode summary, trailer and screencaps; guest stars and main cast list; and more.
This page includes the following topics and synonyms: Herpesviridae, Herpesviridae Infection, Herpes Family of Viruses, Herpesvirus, Human Herpes Virus, Alphaherpesvirus, Alphaherpesvirinae, Betaherpesvirinae, Betaherpesvirus, Gammaherpesvirinae.
The Chelonid fibropapilloma-associated herpesvirus (CFPHV; ChHV5) is believed to be the causative agent of fibropapillomatosis (FP), a neoplastic disease of marine turtles. While clinical signs and pathology of FP are well known, research on ChHV5 has been impeded because no cell culture system for its propagation exists. We have cloned a BAC containing ChHV5 in pTARBAC2.1 and determined its nucleotide sequence. Accordingly, ChHV5 has a type D genome and its predominant gene order is typical for the varicellovirus genus within the alphaherpesvirinae. However, at least four genes that are atypical for an alphaherpesvirus genome were also detected, i.e. two members of the C-type lectin-like domain superfamily (F-lec1, F-lec2), an orthologue to the mouse cytomegalovirus M04 (F-M04) and a viral sialyltransferase (F-sial). Four lines of evidence suggest that these atypical genes are truly part of the ChHV5 genome: (1) the pTARBAC insertion interrupted the UL52 ORF, leaving parts of the gene to either side of
Veterinary Microbiology and Microbial Disease - Google Books ResultP. J. Quinn, B. K. Markey, F. C. Leonard - ‎2011 - 400 pages - MedicalDetection of canine herpesvirus DNA in the ganglionic neurons and the lymph ... Protection of puppies against canine herpesvirus by vaccination of the dams. ...
Early lesions in these cultures (3-10 hours after virus inoculation) consisted of nucleolar sweating and disruption; there was loss of RNA from the nucleo-lus and segregation of nueleolar components (demonstrated by electron microscopy). During the middle phase (10-34 hours) three types of eosinophilic intranuclear inclusion appeared; the inclusions seemed to be formed by progressive transformations. Viral antigen was demonstrated in the nucleus by immuno-fluorescent staining, with viral Show moreEarly lesions in these cultures (3-10 hours after virus inoculation) consisted of nucleolar sweating and disruption; there was loss of RNA from the nucleo-lus and segregation of nueleolar components (demonstrated by electron microscopy). During the middle phase (10-34 hours) three types of eosinophilic intranuclear inclusion appeared; the inclusions seemed to be formed by progressive transformations. Viral antigen was demonstrated in the nucleus by immuno-fluorescent staining, with viral replication ...
4/29/13: Jordan Pacheco crushes a ground-rule double to left center, scoring Josh Rutledge and Tyler Chatwood in the top of the fourth
The KOMP Repository is located at the University of California Davis and Childrens Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at [email protected], US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors [email protected] or +1-510-450-7917 ...
One alternative to destroying the entire wild reindeer population of around 13,000 in the Hemsedal-Hardanger area would be to shoot just a portion of the herds, to reduce the population and keep it small over time.. "But then we have to ask ourselves what kind of wild reindeer population shall we have," mused Strand, the NINA biologist. "Would we still have some that are sick, or shall we take on the demanding job of trying to maintain a herd thats healthy? I think everyone would agree that its not acceptable to have wild reindeer that are not healthy.". CWD was first detected near Hemsedal last fall, and the state provided around NOK 7 million in extra funding to try to fight it. State officials have significantly increased their monitoring of animals at Nordfjella, and theyre instructed to shoot animals showing symptoms of the disease. There also have been attempts to erect fences to try to separate herds.. No one has been able to determine how or why the animals started falling ill. "Were ...
Introduction: : In man, latent herpes simplex virus-1 has been detected in ciliary ganglia. Infection of bulbar conjunctiva and cornea with feline herpesvirus-1 (FHV-1) would allow FHV-1 access to the ciliary ganglia. Purpose: : Determine if active FHV-1 can be isolated from the ciliary ganglia of experimentally infected cats. Methods: : Twelve, juvenile, specific pathogen free (SPF) cats were inoculated with 1x105 TCID50 of the C27 strain of FHV-1 via the ocular and nasal routes. Three, juvenile, SPF cats served as controls. Four infected and 1 control cat were euthanized on day 6 (all animals demonstrating clinical signs), 10 (peak of ocular and respiratory signs), and 30 (virus latent with resolution of clinical signs). The right ciliary ganglia were harvested, placed in 800µl Bovarnicks solution, and homogenized. Cultures were performed in duplicate. A 100µl aliquot of filtered tissue extract was inoculated onto monolayers of Crandall Reese feline kidney cells. The cultures were examined ...
In adult dogs, the virus infects the reproductive tract, which allows it to be sexually transmitted or passed to puppies during birth. The disease can cause abortion, stillbirths, and infertility. It is also an infrequent cause of kennel cough. However, sexual contact is not the primary cause of transmission. Most adult dogs become infected by inhaling the virus via airborne particles spread by coughs or sneezes. It can also be contracted by drinking from a contaminated water bowl, or even just by sniffing or licking another dog that is shedding the virus.. Like other types of herpesvirus, previously infected dogs can from time to time release the virus in vaginal secretions, penile secretions, and discharge from the nose. Raised sores in the vagina or on the penis may be seen during these times. Spread of the disease is controlled by not breeding dogs known to have it. Serology can show what dogs have been exposed (although not all of them will be releasing the virus at that time). Serological ...
In addition to Matrin3 and Raver1, we found a number of other interesting factors that bound to PTB RRM2 and were sensitive to the Y247Q mutation (Joshi et al, 2011), suggesting that their interactions might also be mediated by PRI motifs (Fig 1). These included splicing regulators, proteins involved in the co‐transcriptional‐dependent regulation of splicing and 3′ end processing factors. We did not identify a number of previously identified PTB interactors, including hnRNP‐L, PSF, hnRNPA1, hnRNPA2B1, hnRNPC and MRG15 (Patton et al, 1993; Hahm et al, 1998; Luco et al, 2010; King et al, 2014), although we did identify the helicase DDX3X (King et al, 2014). The lack of overlap could be because we focused on proteins that interact primarily via RRM2. Interesting novel PTB interactors with possible relevance for PTBs splicing regulatory activities include KIAA1967/DBC1/CCAR2 and its paralogue CCAR1, both of which bound strongly to PTB RRM2 in a manner that was sensitive to the PTB Y247Q ...
Hi! I just found your blog too via some other blog that I cant remember right now. Even tho its April I had to read this headless reindeer post cuz I thought maybe you did what I did about 23 years ago ... to my son... who was 3 or 4 at the time. I had a buffet table display set up with a Santa, sleigh and a couple of plastic reindeer for the holidays. One of the reindeers heads became mysteriously disconnected from his body but if you were real careful you could set the head on the body just so and it would stay. Unless you bumped the table or touched it. For some reason my son was scared to death of the headless reindeer. Which struck me as insanely funny. I know, Im demented and really really mean. But my son made the cutest funniest little screechy noises when I even reached for the headless reindeer. I couldnt resist. I tried (not very hard) to resist but I just couldnt. I am demented and mean but I dont have a blog so nobody knows - except my son. And I like to remind him about that ...
Hi! I just found your blog too via some other blog that I cant remember right now. Even tho its April I had to read this headless reindeer post cuz I thought maybe you did what I did about 23 years ago ... to my son... who was 3 or 4 at the time. I had a buffet table display set up with a Santa, sleigh and a couple of plastic reindeer for the holidays. One of the reindeers heads became mysteriously disconnected from his body but if you were real careful you could set the head on the body just so and it would stay. Unless you bumped the table or touched it. For some reason my son was scared to death of the headless reindeer. Which struck me as insanely funny. I know, Im demented and really really mean. But my son made the cutest funniest little screechy noises when I even reached for the headless reindeer. I couldnt resist. I tried (not very hard) to resist but I just couldnt. I am demented and mean but I dont have a blog so nobody knows - except my son. And I like to remind him about that ...
Pseudorabies Virus兔多克隆抗体(ab3534)经WB, IHC, ICC实验严格验证,被5篇文献引用并得到1个独立的用户反馈。所有产品均提供质保服务,中国75%以上现货。
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TY - JOUR UR - http://lib.ugent.be/catalog/pug01:1153143 ID - pug01:1153143 LA - eng TI - Comparative analysis of replication characteristics of BoHV-1 subtypes in bovine respiratory and genital mucosa explants: a phylogenetic enlightenment PY - 2011 JO - (2011) VETERINARY RESEARCH SN - 0928-4249 PB - 2011 AU - Steukers, Lennert 002002270865 802000520297 AU - Vandekerckhove, Annelies UGent 802000137250 002000112516 AU - Van Den Broeck, Wim DI03 801000970865 0000-0001-6683-5658 AU - Glorieux, Sarah 001999359855 801001865386 AU - Nauwynck, Hans DI04 801000719877 0000-0001-5470-0713 AB - In general, members of the Alphaherpesvirinae use the epithelium of the upper respiratory and/or genital tract as a preferential site for primary replication. Bovine herpesvirus type 1 (BoHV-1) may replicate at both sites and cause two major clinical entities designated as infectious bovine rhinotracheitis (IBR) and infectious pustular vulvovaginitis/balanoposthitis (IPV/IPB) in cattle. It has been hypothesized ...
Its fast and painless. It could be feline herpes, also known as feline viral rhinopneumonitis (FVR) , rhinotracheitis virus and feline herpesvirus type 1 (FHV-1) , and one of the most common causes of upper respiratory infections in cats. "That really was definitive proof that a single, non-mutated copy of this gene is enough to allow people to mount a response to the virus," says Ciancanelli. Occidental Grand Promorm - Punta Cana , Zomervakantieatlas.nl Priority STD Testing in Virginia has locations across the entire state making it easy to get tested. CIs at the 95% level were calculated for the odds ratios (ORs). HPV vaccines may help prevent some of the HPV infections that cause genital warts.Your health care provider usually diagnoses genital warts by seeing them. Psychic?. Then i went there today and they said they handed out tickets. Signs and Symptoms * Warts * Itching around the anus * Skin Burning sensation * Vaginal itching Transmission Spreads by skin-to-skin contact or having ...
The DNA sequence of the whole of the short unique region (U S ) and that of part of the short terminal repeat (TR S ) of herpesvirus of turkeys (HVT) were determined. HVT U S is 8·6 kbp long and contains eight potential open reading frames (ORFs). Seven of these have counterparts in the U S of herpes simplex virus type 1 (HSV-1). The homologous proteins include US1, US2, US10, protein kinase (US3) and the glycoproteins gD, gI and gE. In addition, HVT contains one ORF which has a counterpart in the U S of Marek's disease virus (MDV) but is not homologous to any other known herpesvirus gene. Although HVT and MDV proteins encoded by U S genes have evident similarities with proteins encoded by alphaherpesviruses, multiple alignment analysis of predicted amino acid sequences show that HVT proteins are more closely related to MDV proteins than to homologous proteins of mammalian alphaherpesviruses. The percentage amino acid identity between HVT and MDV U S -encoded proteins ranges from 35 to 65, the
Feline herpesvirus (FHV-1) is the virus that causes rhinotracheitis in cats. The most common eye conditions caused by FHV-1 are conjunctivitis and keratitis
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Abstract Varicella-zoster virus (VZV) is a neurotropic human alphaherpesvirus and the causative agent of varicella and herpes zoster. VZV reactivation from latency in sensory nerve..
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While reindeer arent native to this area, since they were flying overhead during the recent Christmas holiday, I got to wondering why they dont live around here. With all this snow and ice, it seems like they would feel right at home.
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Different alphaherpesviruses, including pseudorabies virus (PRV), are able to cross the basement membrane barrier in nasal respiratory epithelium. As a first step in investigating this invasion process, a detailed quantitative analysis system was set up to determine the kinetics of horizontal and vertical virus spread in nasal explants, using the virulent PRV strain 89V87. Plaque latitudes, total depths, depths measured from the basement membrame and volumes were determined at 0, 12, 24 and 36 h post inoculation (pi). PRV 89V87 was found to spread in a plaquewise manner and to cross the basement membrane between 12 and 24 hpi. During the 1960s-1970s, an increase in PRV virulence has been reported. To analyse potential differences in efficiency of infection and spread for different historical PRV strains, single infected cells and plaques of infected cells were quantified at 12 and 36 hpi in nasal mucosa explants for seven European PRV strains, isolated in the 1960s (Becker, NIA1), the 1970s ...
The two viruses commonly associated with cat flu or snuffles are the Feline Herpesvirus and the Feline Calicivirus. Both cause upper respiratory symptoms such as sneezing, coughing, conjunctivitis and discharge from the nose and eyes. The Herpesvirus tends to cause more severe symptoms. Ulcers on the tongue and chronic inflammation of the gums may also be seen with Calicivirus infection. Cats become infected by close contact with infected cats. Cats are at greatest risk of contracting snuffles at a boarding/breeding cattery or animal shelter. Recovered cats may continue to shed the virus without showing symptoms potentially infecting many animals.. ...
The ability to establish lifelong latency after primary infection is a common denominator of large DNA viruses of the Herpesviridae family. Herpes viruses are endemic to humans worldwide and contribute to the meta-genome of 70-100% of the worlds population. The significance of herpes viruses as pathogens has been increasingly recognized during the past few decades, with the escalation in the number of patients undergoing immunosuppressive therapy after organ or bone marrow transplantation, and the rising incidence of AIDS. The ability of these viruses to ensure their survival by controlling cellular and immunological functions [1] has focused attention on their potential role in the development of vascular [2] and autoimmune syndromes [3], cancers [4], and as possible co-factors for acquisition of HIV [5]. In addition, these viruses have co-evolved with, and shaped, the immune systems of their hosts. The secrets of immunology can only be unlocked efficiently by using well-adapted pathogens like ...
A method for preventing lesions caused by a virus of the Herpesviridae or Poxviridae family, comprising topically applying a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C
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The Lions Club Reindeer Run is a CARA Emerging Race. Race hosted by the Lions Club in conjunction with the Wheaton Park District.
After training for their yearly all-night flight, these reindeer need to refuel. Have your kid add a little color to this picture of them breaking for a snack.
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The glomerular injury of preeclampsia manifests as a clinical triad, namely, hypertension, albuminuria, and a loss of intrinsic filtration capacity that lowers the GFR. Although we estimate that filtration capacity, as approximated by an ultrafiltration coefficient (Kf), is depressed by ,50% at the end of pregnancy (postpartum day 1, Table 3), this phenomenon is not widely recognized by clinicians. This is because GFR depression in clinical practice is identified by the presence of azotemia. The absence of overt azotemia (usually defined in women as serum creatinine ,1.2 mg/dl) in preeclamptic mothers during postpartum weeks 1 and 2 obscured the extent to which GFR and computed Kf were depressed in these subjects compared with healthy gravid control subjects.. We examined glomerular structure and ultrastructure in those subjects of the present report who were studied on day 1. We undertook a morphometric analysis of transmission and scanning electron photomicrographs (13). We showed that reduced ...
... has been talked and written about so much the last few years that it seems that there isnt anything left to be said. It may be that so much has been said about the disease that now is the time to review the disease as it relates to Kansas swine producers. First of all, Id like to discuss briefly two factors that need to be clarified: (1), pseudorabies is not to be confused with rabies--there are no recorded instances of humans being affected by the virus; and (2), pseudorabies is not a new disease. First reported in scientific literature by Aujeszky in 1902, Aujeszkys disease is one of its synonyms. A review of the literature published in this country suggests that pseudorabies has been a problem at least as far back as 1813. It has now become a big problem in the swine industry. Pseudorabies is caused by a herpes virus. A fairly resistant virus, it can persist in bedding for 10 days at 75 F. or for 30 days at 65 ̊ F., and on a wooden floor for 7 weeks. It can survive for 6 ...
Aujeszkys disease virus (ADV) is an alphaherpesvirus that causes Aujeszkys disease (AD) in pigs and is present worldwide. Some countries are free from AD, while others, like Poland, just starting eradication program. The aim of the study was the determination of passive...
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Poor Rudolph grew up ostracized for his glowing red schnoz; like children, the reindeer in the classic Christmas story made fun of Rudolph for being different and abnormal. Turns out he wasnt that weird, or at least not the only reindeer to ever be born with a red nose. Smithsonian Mag posted a study from researchers in Norway and the Netherlands about a sliver of the reindeer population who do, in reality, have reddish noses.. Alas, these red noses dont glow in the dark. But the scientific explanation is pretty cool, anyway. The researchers found that some reindeer have red noses due to densely packed blood vessels at the tips of their snouts. Their Christmas-themed explanation:. "The nasal microcirculation of reindeer is richly vascularised, with a vascular density 25% higher than that in humans. These results highlight the intrinsic physiological properties of Rudolphs legendary luminous red nose, which help to protect it from freezing during sleigh rides and to regulate the temperature of ...
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HerpesviridaeHerpesviridae

Subfamily Alphaherpesvirinae (organism), Subfamily Alphaherpesvirinae, Subfamily alphaherpesvirinae, NOS. Swedish. ... Alphaherpesvirinae. Spanish. subfamilia: alphaherpesvirinae, subfamilia: virus del grupo herpes simplex, subfamilia ... Alphaherpesvirinae (C0206557) Definition (CSP). a subfamily of Herpesviridae; replicate rapidly and latent infection is often ... Types: Alphaherpesvirinae. *Simplexvirus (Herpes Simplex Virus). *Human Herpes Virus 1: Oral Herpes ...
more infohttp://www.fpnotebook.com/legacy/ID/Virus/Hrpsvrd.htm

ORBi: Browsing ORBiORBi: Browsing ORBi

Particularly well conserved among Alphaherpesvirinae are the putative functional domains of the DNApol and MDBP proteins which ...
more infohttp://orbi.ulg.ac.be/browse?type=journal&value=Archives+of+Virology

Alphaherpesvirinae - WikipediaAlphaherpesvirinae - Wikipedia

Alphaherpesvirinae at the US National Library of Medicine Medical Subject Headings (MeSH) Viralzone: Alphaherpesvirinae ICTV ... Alphaherpesvirinae is a subfamily of Herpesviridae, primarily distinguished by reproducing more quickly than other subfamilies ... In animal virology the most important herpesviruses belong to the Alphaherpesvirinae. Pseudorabies virus is the causative agent ... Group: dsDNA Order: Herpesvirales Family: Herpesviridae Sub-Family: Alphaherpesvirinae Genus: Iltovirus Gallid herpesvirus 1 ...
more infohttps://en.wikipedia.org/wiki/Alphaherpesvirinae

Canine herpesvirus - WikipediaCanine herpesvirus - Wikipedia

Alphaherpesvirinae. Genus:. Varicellovirus. Species:. Canine herpesvirus 1 (CHV-1). Canine herpesvirus (CHV) is a virus of the ...
more infohttps://en.wikipedia.org/wiki/Canine_herpesvirus

Virus-Taxonomie - WikipediaVirus-Taxonomie - Wikipedia

Unterfamilie Alphaherpesvirinae. *Genus Iltovirus. *Genus Mardivirus. *Genus Scutavirus. *Genus Simplexvirus. *Genus ...
more infohttps://de.wikipedia.org/wiki/Virus-Taxonomie

Virus varicella-zoster - Wikipedia bahasa Indonesia, ensiklopedia bebasVirus varicella-zoster - Wikipedia bahasa Indonesia, ensiklopedia bebas

Virus varicella-zoster adalah virus penyebab cacar air dan cacar ular (herper zoster).[1] Inang dari virus ini hanya terbatas pada manusia dan primata (simian). Stuktur partikel virus (virion) varicella-zoster berukuran 120-300 nm.[2] Genom virus ini berukuran 125 kb (kilo-basa) dan mengandung sedikitnya 69 daerah yang mengkodekan gen-gen tertentu.[1] Virion terdiri dari glikoprotein, kapsid, amplop (selubung) virus, dan nukleokapsid yang melindungi bagian inti berisi DNA genom utas ganda.[1] Bagian nukleokapsid berbentuk ikosahedral, berdiameter 100-110 nm, dan terdiri dari 162 protein yang disebut kapsomer.[2] Virus ini akan mengalami inaktivasi pada suhu 56-60 °C dan menjadi tidak berbahaya apabila bagian amplop (selubung) dari virus ini rusak.[1] Penyebaran virus ini dapat terjadi melalui pernapasan.[1]. ...
more infohttps://id.wikipedia.org/wiki/Virus_varicella-zoster

The Big Picture Book of Viruses - Baltimore ListingThe Big Picture Book of Viruses - Baltimore Listing

Alphaherpesvirinae:. Simplexvirus. human herpesvirus 1. Vertebrates. Varicellovirus. human herpesvirus 3. Vertebrates. ...
more infohttp://www.virology.net/Big_Virology/BVFamilyGroup.html

HerpesviridaeHerpesviridae

Subfamily Alphaherpesvirinae (organism), Subfamily Alphaherpesvirinae, Subfamily alphaherpesvirinae, NOS. Swedish. ... Alphaherpesvirinae. Spanish. subfamilia: alphaherpesvirinae, subfamilia: virus del grupo herpes simplex, subfamilia ... Alphaherpesvirinae (C0206557) Definition (CSP). a subfamily of Herpesviridae; replicate rapidly and latent infection is often ... Types: Alphaherpesvirinae. *Simplexvirus (Herpes Simplex Virus). *Human Herpes Virus 1: Oral Herpes ...
more infohttps://fpnotebook.com/legacy/ID/Virus/Hrpsvrd.htm

Recombinant DNA Research and Viruses | SpringerLinkRecombinant DNA Research and Viruses | SpringerLink

Cloning of the DNA of Alphaherpesvirinae Andrew Davison, Frazer Rixon. Pages 103-124 ...
more infohttps://link.springer.com/book/10.1007%2F978-1-4613-2565-9

Varicella-zoster virus | MSDSonlineVaricella-zoster virus | MSDSonline

CHARACTERISTICS: Herpesviridae, Alphaherpesvirinae; dsDNA, 100nm diameter, enveloped, icosahedral capsid SECTION II - HEALTH ...
more infohttps://www.msdsonline.com/resources/msds-resources/free-safety-data-sheet-index/varicella-zoster-virus/

Herpes simplex virus - wikidocHerpes simplex virus - wikidoc

Alphaherpesvirinae. Genus: Simplexvirus. Species Herpes simplex virus 1 (HSV-1). Herpes simplex virus 2 (HSV-2). ...
more infohttp://www.wikidoc.org/index.php/Herpesvirus

UL4 - Nuclear protein UL4 - Human herpesvirus 1 (strain 17) (HHV-1) - UL4 gene & proteinUL4 - Nuclear protein UL4 - Human herpesvirus 1 (strain 17) (HHV-1) - UL4 gene & protein

Belongs to the alphaherpesvirinae HHV-1 UL4 family.Curated. Family and domain databases. Integrated resource of protein ... Viruses › dsDNA viruses, no RNA stage › Herpesvirales › Herpesviridae › Alphaherpesvirinae › Simplexvirus › Human herpesvirus 1 ...
more infohttps://www.uniprot.org/uniprot/P10188

Frontiers | Complement Evasion Strategies of Viruses: An Overview | MicrobiologyFrontiers | Complement Evasion Strategies of Viruses: An Overview | Microbiology

The members of Alphaherpesvirinae encode gC that target complement. The gCs of HSV type 1 (gC-1) as well as type 2 (gC-2) have ... They are classified into three subfamilies - Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae - and all the ...
more infohttps://www.frontiersin.org/articles/10.3389/fmicb.2017.01117/full

Letter from Bernard Roizman, Committee on Virology, University of Chicago to Harold Varmus  (May 2, 1985)Letter from Bernard Roizman, Committee on Virology, University of Chicago to Harold Varmus (May 2, 1985)

Human herpesvirus 2 (alphaherpesvirinae) simplex 2 Human herpesvirus 3 (alphaherpesvirinae) Varicella-zoster Human herpesvirus ... Subfamily: Alphaherpesvirinae) Classification basis: biologic properties Betaherpesvirinae) Gammaherpsvirinae) Genus: several ...
more infohttps://profiles.nlm.nih.gov/ps/retrieve/ResourceMetadata/MVBBQX

Archive: 15. 6. 2018, Volume: 31, Issue: 3 » Linkos.czArchive: 15. 6. 2018, Volume: 31, Issue: 3 » Linkos.cz

A Possible Role of Human Herpes Viruses Belonging to the Subfamily Alphaherpesvirinae in the Development of Some Cancers ... A Possible Role of Human Herpes Viruses Belonging to the Subfamily Alphaherpesvirinae in the Development of Some Cancers ...
more infohttps://www.linkos.cz/english-summary/klinicka-onkologie-journal/2018-06-15-3-en/

Duck plague - WikipediaDuck plague - Wikipedia

Anatid herpesvirus 1 is under the Herpesvirales order, the Herpesviridae family, the Alphaherpesvirinae subfamily. The genus ...
more infohttps://en.wikipedia.org/wiki/Duck_plague

Time-Dependent Rate Phenomenon in Viruses | Journal of VirologyTime-Dependent Rate Phenomenon in Viruses | Journal of Virology

Molecular phylogeny of the Alphaherpesvirinae subfamily and a proposed evolutionary timescale. J Mol Biol 238:9-22. doi:10.1006 ...
more infohttps://jvi.asm.org/content/90/16/7184

Intracellular Traffic of Herpes Simplex Virus Glycoprotein gE: Characterization of the Sorting Signals Required for Itstrans...Intracellular Traffic of Herpes Simplex Virus Glycoprotein gE: Characterization of the Sorting Signals Required for Itstrans...

1994) Molecular phylogeny of the alphaherpesvirinae subfamily and a proposed evolutionary timescale. J. Mol. Biol. 238:9-22. ... 1994) Glycoprotein E of pseudorabies virus and homologous proteins in other Alphaherpesvirinae. Arch. Virol. 137:209-228. ... Although the Alphaherpesvirinae subfamily has undergone extensive evolutionary divergence (45), the conservation of the sorting ... Multiple sequence alignment of the cytoplasmic tails of the gE homologs forms seven different members of theAlphaherpesvirinae ...
more infohttps://jvi.asm.org/content/73/1/377?ijkey=f62abd7c3c78141c1ff5b34816be36ee3358ce97&keytype2=tf_ipsecsha

A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.

Like other Alphaherpesvirinae subfamily members, bovine herpesvirus 1 (BHV-1) establishes latency in sensory neurons. The ...
more infohttps://www.uniprot.org/citations/21191019

Clinical | Oxford Nanopore TechnologiesClinical | Oxford Nanopore Technologies

Varicella zoster virus (VZV) belongs to the Alphaherpesvirinae subfamily of the Herpesviridae family. The presented data report ...
more infohttps://nanoporetech.com/publications/tags/clinical-health

Immunization Against StranglesImmunization Against Strangles

Within the large family of the Herpesviridae it has been classified under the subfamily of the Alphaherpesvirinae. Owing to its ...
more infohttp://www.vet.cornell.edu/research/Zweig/projects/Osterrieder09.cfm

Iguanid Herpesvirus IgHV-1Iguanid Herpesvirus IgHV-1

Species selective interaction of Alphaherpesvirinae with the unspecific immune system of the host. Arch Virol 1993;130(3-4): ...
more infohttp://www.anapsid.org/ighv1.html

Pathogenicity and Whole Genome Sequence Analysis of a Pseudorabies Virus Strain FJ-2012 Isolated from Fujian, Southern ChinaPathogenicity and Whole Genome Sequence Analysis of a Pseudorabies Virus Strain FJ-2012 Isolated from Fujian, Southern China

PRV is a member of the subfamily Alphaherpesvirinae in the family Herpesviridae belonging to the genus Varicellovirus [1]. ...
more infohttps://www.hindawi.com/journals/cjidmm/2017/9073172/
  • Baloncesto El responsable de este problema de salud (culebrilla) es el mismo virus que causa la varicela: virus del herpes zoster, el más agresivo de la subfamilia de alphaherpesvirinae. (bestskincare101.com)