Alpha linolenic acid. Medical search

A fatty acid that is found in plants and involved in the formation of prostaglandins.

Eighteen-carbon essential fatty acids that contain three double bonds.

Eighteen-carbon essential fatty acids that contain two double bonds.

A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)

FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds.

Long chain organic acid molecules that must be obtained from the diet. Examples are LINOLEIC ACIDS and LINOLENIC ACIDS.

Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)

An omega-6 fatty acid produced in the body as the delta 6-desaturase metabolite of linoleic acid. It is converted to dihomo-gamma-linolenic acid, a biosynthetic precursor of monoenoic prostaglandins such as PGE1. (From Merck Index, 11th ed)

Unsaturated fats or oils used in foods or as a food.

Oils derived from plants or plant products.

A group of compounds that are derivatives of octadecanoic acid which is one of the most abundant fatty acids found in animal lipids. (Stedman, 25th ed)

An enzyme of the oxidoreductase class primarily found in PLANTS. It catalyzes reactions between linoleate and other fatty acids and oxygen to form hydroperoxy-fatty acid derivatives.

The fixed oil obtained from the dried ripe seed of linseed, Linum usitatissimum (L. Linaceae). It is used as an emollient in liniments, pastes, and medicinal soaps, and in veterinary medicine as a laxative. It is also called flaxseed oil. (Dorland, 28th ed)

C22-unsaturated fatty acids found predominantly in FISH OILS.

A family of enzymes that catalyze the stereoselective, regioselective, or chemoselective syn-dehydrogenation reactions. They function by a mechanism that is linked directly to reduction of molecular OXYGEN.

Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.

Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.

A plant genus of the family LINACEAE that is cultivated for its fiber (manufactured into linen cloth). It contains a trypsin inhibitor and the seed is the source of LINSEED OIL.

A plant genus of the family BORAGINACEAE.

Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.

Chemicals used in agriculture. These include pesticides, fumigants, fertilizers, plant hormones, steroids, antibiotics, mycotoxins, etc.

Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.

The study of the physical and chemical properties of a drug and its dosage form as related to the onset, duration, and intensity of its action.

Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.

Trihydroxy derivatives of eicosanoic acids. They are primarily derived from arachidonic acid, however eicosapentaenoic acid derivatives also exist. Many of them are naturally occurring mediators of immune regulation.

An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.

Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).

A group of fatty acids, often of marine origin, which have the first unsaturated bond in the third position from the omega carbon. These fatty acids are believed to reduce serum triglycerides, prevent insulin resistance, improve lipid profile, prolong bleeding times, reduce platelet counts, and decrease platelet adhesiveness.

High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice. (1/510)

Semipurified diets incorporating either perilla oil [high in alpha-linolenate, 18:3(n-3)] or safflower oil [high in linoleate, 18:2(n-6)] were fed to senescence-resistant SAMR1 mouse dams and their pups. Male offspring at 15 mo were examined using behavioral tests. In the open field test, locomotor activity during a 5-min period was significantly higher in the safflower oil group than in the perilla oil group. Observations of the circadian rhythm (48 h) of spontaneous motor activity indicated that the safflower oil group was more active than the perilla oil group during the first and second dark periods. The total number of responses to positive and negative stimuli was higher in the safflower oil group than in the perilla oil group in the light and dark discrimination learning test, but the correct response ratio was lower in the safflower oil group. The difference in the (n-6)/(n-3) ratios of the diets reflected the proportions of (n-6) polyunsaturated fatty acids, rather than those of (n-3) polyunsaturated fatty acids in the brain total fatty acids, and in the proportions of (n-6) and (n-3) polyunsaturated fatty acids in the total polyunsaturated fatty acids of the brain phospholipids. These results suggest that in SAMR1 mice, the dietary alpha-linolenate/linoleate balance affects the (n-6)/(n-3) ratio of brain phospholipids, and this may modify emotional reactivity and learning ability. (+info)

Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men. (2/510)

BACKGROUND: Vegetarians have lower platelet and plasma concentrations of n-3 polyunsaturated fatty acids (PUFAs) than do omnivores. We recently showed that male vegetarians have higher platelet aggregability than do omnivores. OBJECTIVE: We investigated whether male vegetarians (n = 17) who consumed an increased amount of dietary alpha-linolenic acid (ALA) showed any changes in their tissue profile of PUFAs, plasma thromboxane concentrations, platelet aggregability, or hemostatic factors. DESIGN: During the study, all subjects maintained their habitual vegetarian diets except that a proportion of dietary fat was replaced with vegetable oils and margarines that were provided. Initially, all subjects consumed a low-ALA diet (containing safflower oil and safflower oil-based margarine) for 14 d; they then consumed either a moderate-ALA diet (containing canola oil and canola oil-based margarine) or a high-ALA diet (containing linseed oil and linseed oil-based margarine) for 28 d. Blood samples were collected at day 0 (baseline), day 14, and day 42. RESULTS: Eicosapentaenoic acid, docosapentaenoic acid, total n-3 PUFAs, and the ratio of n-3 to n-6 PUFAs were significantly increased (P < 0.05), whereas the ratio of arachidonic acid to eicosapentaenoic acid was decreased (P < 0.05), in platelet phospholipids, plasma phospholipids, and triacylglycerols after either the moderate-ALA or high-ALA diet compared with the low-ALA diet. No significant differences were observed in thrombotic risk factors. CONCLUSION: ALA from vegetable oils (canola and linseed) has a beneficial effect on n-3 PUFA concentrations of platelet phospholipids and plasma lipids in vegetarian males. (+info)

Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. (3/510)

BACKGROUND: Experimental studies in laboratory animals and humans suggest that alpha-linolenic acid (18:3n-3) may reduce the risk of arrhythmia. OBJECTIVE: The objective was to examine the association between dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease (IHD). DESIGN: This was a prospective cohort study. The intake of alpha-linolenic acid was derived from a 116-item food-frequency questionnaire completed in 1984 by 76283 women without previously diagnosed cancer or cardiovascular disease. RESULTS: During 10 y of follow-up, we documented 232 cases of fatal IHD and 597 cases of nonfatal myocardial infarction. After adjustment for age, standard coronary risk factors, and dietary intake of linoleic acid and other nutrients, a higher intake of alpha-linolenic acid was associated with a lower relative risk (RR) of fatal IHD; the RRs from the lowest to highest quintiles were 1.0, 0.99, 0.90, 0.67, and 0.55 (95% CI: 0.32, 0.94; P for trend = 0.01). For nonfatal myocardial infarction there was only a modest, nonsignificant trend toward a reduced risk when extreme quintiles were compared (RR: 0.85; 95% CI: 0.61, 1.19; P for trend = 0.50). A higher intake of oil and vinegar salad dressing, an important source of alpha-linolenic acid, was associated with reduced risk of fatal IHD when women who consumed this food > or =5-6 times/wk were compared with those who rarely consumed this food (RR: 0.46; 95% CI: 0.27, 0.76; P for trend = 0.001). CONCLUSIONS: This study supports the hypothesis that a higher intake of alpha-linolenic acid is protective against fatal IHD. Higher consumption of foods such as oil-based salad dressing that provide polyunsaturated fats, including alpha-linolenic acid, may reduce the risk of fatal IHD. (+info)

Prevention of sudden cardiac death by dietary pure omega-3 polyunsaturated fatty acids in dogs. (4/510)

BACKGROUND: Rat diets high in fish oil have been shown to be protective against ischemia-induced fatal ventricular arrhythmias. Increasing evidence suggests that this may also apply to humans. To confirm the evidence in animals, we tested a concentrate of the free fish-oil fatty acids and found them to be antiarrhythmic. In this study, we tested the pure free fatty acids of the 2 major dietary omega-3 polyunsaturated fatty acids in fish oil: cis-5,8,11,14, 17-eicosapentaenoic acid (C20:5omega-3) and cis-4,7,10,13,16, 19-docosahexaenoic acid (C22:6omega-3), and the parent omega-3 fatty acid in some vegetable oils, cis-9,12,15-alpha-linolenic acid (C18:3omega-3), administered intravenously on albumin or a phospholipid emulsion. METHODS AND RESULTS: The tests were performed in a dog model of cardiac sudden death. Dogs were prepared with a large anterior wall myocardial infarction produced surgically and an inflatable cuff placed around the left circumflex coronary artery. With the dogs running on a treadmill 1 month after the surgery, occlusion of the left circumflex artery regularly produced ventricular fibrillation in the control tests done 1 week before and after the test, with the omega-3 fatty acids administered intravenously as their pure free fatty acid. With infusion of the eicosapentaenoic acid, 5 of 7 dogs were protected from fatal ventricular arrhythmias (P<0.02). With docosahexaenoic acid, 6 of 8 dogs were protected, and with alpha-linolenic acid, 6 of 8 dogs were also protected (P<0.004 for each). The before and after control studies performed on the same animal all resulted in fatal ventricular arrhythmias, from which they were defibrillated. CONCLUSIONS: These results indicate that purified omega-3 fatty acids can prevent ischemia-induced ventricular fibrillation in this dog model of sudden cardiac death. (+info)

Antisense-mediated depletion of potato leaf omega3 fatty acid desaturase lowers linolenic acid content and reduces gene activation in response to wounding. (5/510)

Fatty acid omega3 desaturases act on membrane lipids to catalyse the formation of trienoic fatty acids, the most abundant in plant tissues being alpha-linolenic acid. This fatty acid is a precursor of jasmonic acid, a plant growth regulator involved in the control of wound-induced gene activation in plants and in the induction of tuberization in potato. We isolated a potato omega3 desaturase cDNA, possibly encoding a plastidial isoform, and used it to investigate its expression pattern throughout plant development and in response to wounding. Plastidial omega3 desaturase gene transcripts accumulate rapidly upon wounding, preceding the jasmonate-dependent induction of the wound-responsive proteinase inhibitor II gene. We generated transgenic potato plants constitutively expressing an antisense RNA to this plastidial omega3 desaturase. Selected transgenic lines in which the cognate omega3 desaturase mRNA is largely depleted show a marked reduction, of up to 60%, in trienoic acids in leaves and tubers. In these lines, a corresponding reduction in jasmonate content and proteinase inhibitor II expression is observed upon wounding. Our results indicate that a reduction in omega3 desaturase mRNA levels compromises the wound-induced activation of proteinase inhibitor II, suggesting that wound-induced synthesis of linolenic acid is required for jasmonic acid production. The antisense-mediated depletion of fatty acid omega3 desaturases is a viable alternative for reducing trienoic fatty acid content in plant species in which a mutant screening approach is not applicable. (+info)

Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. (6/510)

BACKGROUND: Essential fatty acid (EFA) requirements of patients receiving home parenteral nutrition (HPN) are uncertain. OBJECTIVE: The objective was to evaluate the influence of the route of administration (enteral compared with parenteral) on plasma phospholipid EFA concentrations. DESIGN: Intestinal absorption, parenteral supplement of EFAs, and plasma phospholipid EFA concentrations were investigated in balance studies in 4 groups (A, B, C, and D) of 10 patients with short-bowel syndrome and a fecal loss of >2000 kJ/d. Groups A (fat malabsorption <50%) and B (fat malabsorption >50%) did not receive HPN, whereas group C received HPN containing lipids (7.5 and 1.2 g/d linoleic and linolenic acids, respectively) and group D received fat-free HPN. RESULTS: Intestinal absorption of linoleic and linolenic acids was 8.9 and 1.3 g/d and 2. 6 and 0.4 g/d in groups A and B, respectively, whereas EFA absorption was negligible in groups C and D. Thus, intestinal absorption of EFAs in group A corresponded to parenteral EFA supplements in group C, whereas group D was almost totally deprived of EFAs. The median plasma phospholipid concentration of linoleic acid decreased by 21.9%, >16.3%, >13.8%, 11.0%, and >7.7% and linolenic acid by 0.3%, 0.2%, 0.2%, >0.2%, and 0.1%, respectively, in 10 healthy control subjects and groups A, B, C, and D (P < 0.001). CONCLUSIONS: Intestinally absorbed EFAs maintained plasma EFA status better than did an equal quantity of parenterally supplied EFAs. Intravenous requirements of EFAs in patients with negligible absorption of EFAs are probably higher than the amounts recommended to patients with preserved intestinal absorption of EFAs. (+info)

Salicylhydroxamic acid inhibits delta6 desaturation in the microalga Porphyridium cruentum. (7/510)

Treatment of the microalga Porphyridium cruentum with salicylhydroxamic acid (SHAM) inhibited growth and affected fatty acid composition. At a relatively low concentration (40 microM) SHAM predominantly inhibits Delta6 desaturation. The effect of the inhibitor was most intense in phosphatidylcholine (PC) and phosphatidylethanolamine, in which the proportions of the downstream products of the Delta6 desaturase were reduced, whereas that of the substrate, 18:2, increased. As a result of the availability of 18:2, 18:3omega3, which under normal conditions is not observed, appeared predominantly in chloroplastic lipids. Pulse labeling with linoleic acid has shown that SHAM inhibits Delta6 desaturation almost immediately, suggesting an apparent inhibition of the activity of the desaturase, rather than its synthesis or that of its cofactors. Furthermore, the addition of gamma-linolenic acid to SHAM-inhibited cultures relieved the inhibition. Following exposure to the inhibitor, 18:3omega3 appeared first in chloroplastic glycolipids and only later in PC, indicating that the former are the substrates for the first dedicated step of the proposed omega3 pathway in this alga. (+info)

Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures. (8/510)

Reduction of the highly proliferative terminal end bud (TEB) structures in the developing mammary gland by differentiation to alveolar buds (ABs) and lobules has been suggested to be protective against mammary cancer. Flaxseed is high in alpha-linolenic acid (ALA) and secoisolariciresinol diglycoside (SDG). SDG is the precursor of mammalian lignans, which can affect mammary gland structures. Thus, the objective of this study was to determine the effect of lifetime, gestation and lactation or after-weaning exposure to 5 or 10% flaxseed or SDG and flaxseed oil components on the mammary gland structures of virgin female rat offspring at post-natal day 50. Lifetime or gestation and lactation exposure to flaxseed altered mammary gland structure development, whereas exposure to flaxseed after weaning had no effect. Lifetime or gestation and lactation exposure to 5% flaxseed caused endocrine changes, as suggested by delayed puberty onset and reduced number of estrous cycles. These changes reduced exposure to endogenous estrogens, leading to atrophy of mammary TEB structures. SDG, but not flaxseed oil, at the level found in 5% flaxseed produced similar effects as 5% flaxseed. This suggested that the lignans were the component in flaxseed responsible for the observed effects. Lifetime or gestation and lactation exposure to 10% flaxseed also caused endocrine changes, as suggested by early puberty onset and lengthened cycles due to prolonged estrus. This increased exposure to endogenous estrogens and stimulated mammary gland differentiation, as indicated by fewer TEBs and more ABs. Thus, lifetime or gestation and lactation exposure to 5 or 10% flaxseed induced structural changes in the mammary gland that may potentially reduce mammary cancer risk. (+info)

"Omega-3 fatty acids, fish oil, alpha-linolenic acid". Retrieved 4 February 2014. Montgomery P, Richardson AJ (2008). Montgomery ... Fish oils contain the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), precursors of certain ... both omega-3 acid ethyl esters), Vascepa (ethyl eicosapentaenoic acid), and Epanova (omega-3 carboxylic acids). Often marketed ... Lovaza (omega-3 acid ethyl esters) was approved on 10 November 2004. Omtryg (omega-3 acid ethyl esters) was approved on 23 ...

https://en.wikipedia.org/wiki/Fish_oil

"Omega-3 fatty acids, fish oil, alpha-linolenic acid: MedlinePlus Supplements". Archived from the original on 8 February 2006. ... Regular consumption of omega-3 fatty acids may reduce the likelihood of developing Alzheimer's disease. These fatty acids can ... Sardines are also a natural source of marine omega-3 fatty acids, which may reduce the occurrence of cardiovascular disease. ... November 2002). "Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease". Circulation. 106 (21): 2747-2757 ...

https://en.wikipedia.org/wiki/Sardine

"Omega-3 fatty acids, fish oil, alpha-linolenic acid: MedlinePlus Supplements". Retrieved 2010-01-22. Fish oil supplements may ... These fatty acids may also help lower blood sugar levels a small amount. They are also a good source of vitamin D, calcium, and ... Sardines are a source of omega-3 fatty acids. Sardines are often served in cans, but can also be eaten grilled, pickled, or ... Sardines are also a natural source of marine omega-3 fatty acids, which reduce the occurrence of cardiovascular disease. Recent ...

https://en.wikipedia.org/wiki/Sardines_as_food

Cunnane SC, Ganguli S, Menard C, Liede AC, Hamadeh MJ, Chen ZY, Wolever TM, Jenkins DJ (1993). "High alpha-linolenic acid ... omega-9 fatty acids (oleic acid), and 6% omega-6 fatty acids (linoleic acid); the seeds contain 9% saturated fat, including 5% ... alpha-linolenic acid (ALA), specifically). Flaxseeds produce a vegetable oil known as flaxseed oil or linseed oil, which is one ... as palmitic acid. Flaxseed oil contains 53% 18:3 omega-3 fatty acids (mostly ALA) and 13% 18:2 omega-6 fatty acids. One study ...

https://en.wikipedia.org/wiki/Flax

Isotopic labeling has indicated that nonadienal is formed from alpha-linolenic acid. Such reactions are typically catalyzed by ... "Linoleic and linolenic acid as precursors of the cucumber flavor". Lipids. 6 (5): 351-352. doi:10.1007/BF02531828.. ...

https://en.wikipedia.org/wiki/Trans,cis-2,6-Nonadienal

linolenic, alpha-linolenic, oleic and palmitic acids are present in seeds.[6] ...

https://en.wikipedia.org/wiki/Cercis_canadensis

... eicosapentaenoic acid, docosahexaenoic acid, and alpha-linolenic acid; and the omega-9 fatty acid, mead acid. Certain types of ... arachidonic acid, linoleic acid, dihomo-γ-linolenic acid, and adrenic acid; the omega-3 fatty acids, ... ALOX15 actually prefers linoleic acid over arachidonic acid, metabolizing linoleic acid to 12-hydroperoxyoctadecaenoic acid (13 ... polyunsaturated fatty acids such as the Hydroxyeicosatetraenoic acids and HODEs (i.e. hydroxyoctadecaenoic acids). ...

https://en.wikipedia.org/wiki/Lipoxygenase

"MedlinePlus Herbs and Supplements: Omega-3 fatty acids, fish oil, alpha-linolenic acid". Archived from the original on May 18, ... Folic acid might also be counter-productive for patients taking 6-MP and related drugs that inhibit all cell division. It is ... Fish oil, eicosapentaenoic acid (EPA) is not conclusive. Slow release phosphatidylcholine has some evidence of benefit in ... It works by inhibiting folic acid, which is necessary for DNA replication and, therefore, cell division. TNF is a protein that ...

https://en.wikipedia.org/wiki/Management_of_ulcerative_colitis

... seed oil contains fatty acids, such as oleic acid and alpha-linolenic acid. Canned pumpkin is often recommended by ... alpha and beta carotene, all of which are provitamin A compounds converted to vitamin A in the body. All pumpkins are winter ...

https://en.wikipedia.org/wiki/Pumpkin

Most oxylipins in the body are derived from linoleic acid or alpha-linolenic acid. Linoleic acid oxylipins are usually present ... despite the fact that alpha-linolenic acid is more readily metabolized to oxylipin. Linoleic acid oxylipins can be anti- ... Lowering dietary linoleic acid results in fewer linoleic acid oxylipins in humans. From 1955 to 2005 the linoleic acid content ... The omega-3 eicosapentaenoic acid (EPA)-derived and docosahexaenoic acid (DHA)-derived oxylipins are anti-inflammatory and ...

https://en.wikipedia.org/wiki/Oxylipin

... alpha-linolenic acid, an omega-3 fatty acid. Kiwifruit pulp contains carotenoids, such as provitamin A beta-carotene, lutein ... "Seed Oil Fatty Acids - Gesundheitsratgeber: Mit Expertentipps die Gesundheit fördern". jameda.de. Retrieved 4 September 2007.[ ...

https://en.wikipedia.org/wiki/Kiwifruit

These esters are characterized by high levels of polyunsaturated fatty acids, especially alpha-linolenic acid. One common ... Diene-containing fatty acid derivatives, such as those derived from linoleic acid, are especially prone to this reaction ... Monounsaturated fatty acids, such as oleic acid, are slower to undergo drying because the allylic radical intermediates are ... These salts are derived from the carboxylates of lipophilic carboxylic acids, such as naphthenic acids to make the complexes ...

https://en.wikipedia.org/wiki/Drying_oil

A precursor of jasmolone could be alpha-linolenic acid with a 12-oxophytodienoic acid intermediate. The chain shortening could ... 12-Oxophytodienoic acid is also used in the production of jasmonic acid. Jasmonic acid is used in the production of secondary ... α-linolenic acid. Lipooxygenase specifically binds to polyunsaturated fatty acids that have a cis,cis-1,4-pentadiene present. ... α-Linolenic acid undergoes a radical oxidation with O2 and lipoxygenase to form a peroxide. Lipoxygenase is an iron-containing ...

https://en.wikipedia.org/wiki/Jasmolone

... octadecatrienoic acids from alpha-linolenic acid". The Journal of Biological Chemistry. 270 (33): 19330-6. doi:10.1074/jbc. ... Z-octadecadienoic acid, 10-hydroxy-8E,12Z-octadecadienoic acid, and 12-hydroxy-9Z-13-E-octadecadienoic acid.[19] 4- ... linoleic acid, over arachidonic acid, converting it to 13-hydroperoxy-9Z,11E-octadecadienoic acid (13-HpODE).[1][2] The enzyme ... E-octadecadienoic acid, 9-hydroxy-10E,12-Z-octadecadienoic acid, and 11-hydroxy-9Z,12Z-octadecaenoic acid while singlet oxygen ...

https://en.wikipedia.org/wiki/13-oxoODE

Omega-3 fatty acids that support brain development and function are alpha-linolenic acid, docosahexaenoic acid (DHA) and ... Alpha-linolenic acid can be acquired from oils and seeds. Omega-6 fatty acids are also needed in feline cognition diets. The ... and Rapoport SI (2000). "Nutritional deprivation of alpha-linolenic acid decreases but does not abolish turnover and ... 2006). "Metabolic basis for the essential nature of fatty acids and the unique dietary fatty acid requirement of cats". Journal ...

https://en.wikipedia.org/wiki/Cat_intelligence

The fungus also contains various fatty acids, notably myristic, palmitic, stearic, oleic, alpha-linolenic, and linoeic acid. ...

https://en.wikipedia.org/wiki/Geastrum_triplex

Cunnane SC, Ganguli S, Menard C, Liede AC, Hamadeh MJ, Chen ZY, Wolever TM, Jenkins DJ (1993). "High alpha-linolenic acid ... oleic acid), and 6% omega-6 fatty acids (linoleic acid); the seeds contain 9% saturated fat, including 5% as palmitic acid.[31] ... As a percentage of total fat, flaxseeds contain 54% omega-3 fatty acids (mostly ALA), 18% omega-9 fatty acids ( ... Three natural phenolic glucosides, secoisolariciresinol diglucoside, p-coumaric acid glucoside, and ferulic acid glucoside, can ...

https://en.m.wikipedia.org/wiki/Flax

2009). "Bioavailability of alpha-linolenic acid from flaxseed diets as a function of the age of the subject". European Journal ... "Suppression of Cardiac Myocyte Hypertrophy by Conjugated Linoleic Acid". Journal of Biological Chemistry. American Society for ...

https://en.wikipedia.org/wiki/Saint_Boniface_Hospital

... phospholipase C will cause the release of alpha-linolenic acid for JA synthesis. In the first step, alpha-linolenic acid is ... JA is synthesized from alpha-linolenic acid, which can be released from the plasma membrane by certain lipase enzymes. For ... This undergoes reduction and three rounds of beta oxidation to form jasmonic acid. Jasmonic Acid Synthesis Peter J Davies. ... ISBN 978-0-7923-2985-5. Hans Weber (2002). "Fatty acid-derived signals in plants". Trends in Plant Science. 7 (5): 217-224. doi ...

https://en.wikipedia.org/wiki/Octadecanoid_pathway

Purslane has been identified as the richest vegetable source of alpha-linolenic acid, an essential omega-3 fatty acid. ... The sour taste is due to oxalic and malic acid, the latter of which is produced through the crassulacean acid metabolism (CAM) ... A P Simopoulos (2013). "Common purslane: a source of omega-3 fatty acids and antioxidants". Journal of the American College of ... "C 4 and crassulacean acid metabolism within a single leaf: Deciphering key components behind a rare photosynthetic adaptation ...

https://en.wikipedia.org/wiki/Portulaca_oleracea

... alpha-linolenic acid". Mayo Clinic. 2017. Retrieved 24 May 2017.. *^ a b c "Omega-3 Fatty Acids and Health: Fact Sheet for ... Chemical structure of alpha-linolenic acid (ALA), an essential omega−3 fatty acid. ... Omega-3 fatty acids have a double bond three carbons away from the methyl carbon, whereas omega-6 fatty acids have a double ... The illustration below shows the omega-6 fatty acid, linoleic acid. While it is the nutritional aspects of polyunsaturated fats ...

https://en.m.wikipedia.org/wiki/Polyunsaturated

"Omega-3 fatty acids, fish oil, alpha-linolenic acid". Mayo Clinic. 2017. Retrieved 24 May 2017.. ... Chemical structure of alpha-linolenic acid (ALA), an essential omega−3 fatty acid. ... Omega-3 fatty acids have a double bond three carbons away from the methyl carbon, whereas omega-6 fatty acids have a double ... The illustration below shows the omega-6 fatty acid, linoleic acid. While it is the nutritional aspects of polyunsaturated fats ...

https://en.m.wikipedia.org/wiki/Polyunsaturated_fat

... seed oil is rich in vitamin E and unsaturated fatty acids, including alpha-linolenic acid and gamma-linolenic acid ... Traitler, H.; Winter, H.; Richli, U.; Ingenbleek, Y. (1984). "Characterization of gamma-linolenic acid in Ribes seed". Lipids. ... It can be made into jams and jellies which set readily because of the fruit's high content of pectin and acid. For culinary use ...

https://en.wikipedia.org/wiki/Blackcurrant

... stearidonic acid and alpha-linolenic acid. Tisochrysis lutea contains betain lipids and phospholipids. The haptophytes were ... They contain a large amount of polyunsaturated fatty acids such as docosahexaenoic acid (DHA), ... total lipid content and fatty acid composition of recently isolated tropical microalgae Isochrysis sp., Nitzschia closterium, ...

https://en.wikipedia.org/wiki/Haptophyte

Omega-3 fatty acids that support brain development and function are alpha-linolenic acid, docosahexaenoic acid (DHA) and ... Alpha-linolenic acid, was recommended at 0.02% on a dry matter basis and 0.05g per 1000 kcal ME per day. Omega-6 fatty acids ... Alpha-linolenic acid can be acquired from oils and seeds. In kittens and juvenile felines, omega-3 fatty acids are very ... and Rapoport SI (2000). "Nutritional deprivation of alpha-linolenic acid decreases but does not abolish turnover and ...

https://en.wikipedia.org/wiki/Cat_cognitive_support_diets

Alpha-linolenic acid (ALA), an omega-3 fatty acid, is found in walnuts, seeds, and vegetable oils, such as canola and flaxseed ... Lactic acid, an alpha-hydroxy acid derived from animal milk, is used in moisturizers; allantoin- from the comfrey plant or cows ... "Omega-3 Fatty Acids and Health", Office of Dietary Supplements, National Institutes of Health. The Adequate Intake for ALA is ... "Omega-3 Fatty Acids and Health", Office of Dietary Supplements, National Institutes of Health. Adequate Intakes for EPA and DHA ...

https://en.wikipedia.org/wiki/Veganism

... alpha-linolenic acid (ALA), linoleic acid (LA), stearidonic acid (SDA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA ... Plant foods can provide alpha-linolenic acid which the human body uses to synthesize the long-chain n-3 fatty acids EPA and DHA ... it is unlikely that supplementation with alpha-linolenic acid will significantly increase levels.[clarification needed] ... However, certain algae such as spirulina are good sources of gamma-linolenic acid (GLA), ...

https://en.wikipedia.org/wiki/Vegetarianism

These include two specific amino acids, alpha-linolenic acid and linoleic acid without which life is not sustainable in the ... All other fatty acids can be synthesised from dietary fats. Similarly human life requires a range of vitamins to be present in ...

https://en.wikipedia.org/wiki/Human_biology

Alpha-Lipoic acid. *Ambrisentan. *AMI-193. *Amlodipine besylate. *Antimycotics. *Artemisinin. *Aurothioglucose. *Bile acids ...

https://en.wikipedia.org/wiki/Indinavir

S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid ...

https://en.wikipedia.org/wiki/Levothyroxine

Alpha-linolenic acid and zinc are also found in some nuts and help condition the hair and prevent hair shedding that can be ... The essential omega-3 fatty acids, protein, vitamin B12, and iron, found in fish sources, prevent a dry scalp and dull hair ... The sebaceous glands in human skin produce sebum, which is composed primarily of fatty acids. Sebum acts to protect hair and ... When sebum and sweat combine on the scalp surface, they help to create the acid mantle, which is the skin's own protective ...

https://en.wikipedia.org/wiki/Hair_care

TTA acts as a peroxisome proliferator-activated receptor alpha (PPARα) agonist and increases mitochondrial fatty acid oxidation ... α-Linolenic (18:3). *Stearidonic (18:4). *Dihomo-α-linolenic (20:3) ... Tetradecylthioacetic acid (TTA) is a synthetic fatty acid used as a nutritional supplement. ... possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation". Diabetes, Obesity & Metabolism ...

https://en.wikipedia.org/wiki/Tetradecylthioacetic_acid

Alpha-linolenic acid, cardiovascular disease and sudden death. pubmed. 2007-01-18 कथं। ... Fatty acids play an important role in the life and death of cardiac cells because they are essential fuels for mechanical and ... External blockade...by polyunsaturated fatty acids. pubmed. 2007-01-18 कथं। - see page 1 of this link ... Antiarrythmic effects of omega-3 fatty acids. pubmed. 2007-01-18 कथं। ...

https://new.wikipedia.org/wiki/कार्दियाक_अरिदमिया

... which inhibits the conversion of short-chain fatty acids such as alpha-Linolenic acid (ALA), which is found in most vegetarian ... omega-6 fatty acids, dietary fibre, carotenoids, folic acid, vitamin C, vitamin E, potassium and magnesium. They are possibly ... Omega-3 fatty acidsEdit. Flaxseeds are a rich source of ALA, but contains negligible amounts of DHA and EPA, the long-chain ... and docosahexaenoic acid (DHA). Vegetarian diets may also have a high ratio of omega-6 fatty acids to O3FAs, ...

https://en.m.wikipedia.org/wiki/Vegetarian_nutrition

... and alpha-linolenic acids.[20]. Hempseed's amino acid profile is comparable to other sources of protein such as meat, milk, ... of the energy in hempseed is in the form of fats and essential fatty acids,[19] mainly polyunsaturated fatty acids, linoleic, ... eggs and soy.[20] Protein digestibility-corrected amino acid scores (PDCAAS), which attempt to measure the degree to which a ... products through the use of the protein digestibility-corrected amino acid score method". Journal of Agricultural and Food ...

https://en.m.wikipedia.org/wiki/Hemp

... and palmitic acid[69] and dietary myristic[70] and palmitic[70] saturated fatty acids and serum palmitic combined with alpha- ... Saturated fat profile of common foods; Esterified fatty acids as percentage of total fat[10] Food. Lauric acid. Myristic acid. ... γ-Linolenic (18:3). *Calendic (18:3). *Pinolenic (18:3). *Dihomo-γ-linolenic (20:3) ... polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol". European Food Safety Authority. ...

https://en.wikipedia.org/wiki/Saturated_fats

Antibacterials: nucleic acid inhibitors (J01E, J01M). Antifolates. (inhibits. purine metabolism,. thereby inhibiting. DNA and ...

https://en.wikipedia.org/wiki/Rifaximin

... linoleic acid and alpha-linolenic acid) and singly allylic sites (oleic acid) ... Compounds containing the C=C−CH2−C=C linkages, e.g. linoleic acid derivatives, are prone to autoxidation, which can lead to ...

https://en.wikipedia.org/wiki/Allyl_group

Precursors: Linoleic acid. *γ-Linolenic acid (gamolenic acid). *Dihomo-γ-linolenic acid ... see Gq alpha subunit#function and Ga subunit#function for details); the order of potency of the cysLTs in stimulating CysLTR2 ... Polymorphism in the CysLTR2 gene resulting in a single amino acid substitution, M201V (i.e. amino acid methionine changed for ... CysLTR2 encodes a protein composed of 347 amino acids and shows only modest similarity to the CysLTR1 gene in that its protein ...

https://en.wikipedia.org/wiki/Cysteinyl_leukotriene_receptor_2

It suppresses stomach acid secretion by specific inhibition of the H+/K+-ATPase system found at the secretory surface of ... "2014 Treatments for Acid-Peptic Diseases". University of Minnesota Medical School Duluth. Archived from the original on April ... An updated review of its pharmacology and therapeutic use in acid-related disorders". Drugs. 42 (1): 138-70. doi:10.2165/ ... Because this enzyme system is regarded as the acid (proton, or H+) pump within the gastric mucosa, omeprazole inhibits the ...

https://en.wikipedia.org/wiki/Prilosec

2S,5R,6R)-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ...

https://en.wikipedia.org/wiki/Nafcillin

Resorcylic acid lactones (e.g., zearalanone, α-zearalenol, β-zearalenol, zearalenone, zeranol (α-zearalanol), taleranol ( ... "Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta". ...

https://en.wikipedia.org/wiki/5-Androstenediol

... which can be made in the human body from the omega-3 essential fatty acid alpha-linolenic acid (ALA), or taken in through ... Fatty acids such as conjugated linoleic acid, catalpic acid, eleostearic acid and punicic acid, in addition to providing energy ... Essential fatty acids[edit]. Main article: Essential fatty acids. Most fatty acids are non-essential, meaning the body can ... As there is no protein or amino acid storage provision, amino acids must be present in the diet. Excess amino acids are ...

https://en.wikipedia.org/wiki/Nutrition

Valerian constituents (e.g., isovaleric acid, isovaleramide, valerenic acid, valerenol). *Unsorted benzodiazepine site positive ... Alpha lipoic acid. *Benfotiamine. *Botulinum toxin A. *Bupropion. *Cannabinoids (e.g., cannabis, dronabinol, nabilone) ... Valproic acid and valnoctamide both inhibit microsomal epoxide hydrolase (MEH), the enzyme responsible for the breakdown of ... and valproic acid.[12] Drugs that decrease the metabolism of carbamazepine or otherwise increase its levels include ...

https://en.wikipedia.org/wiki/Tegretol

Representative triglyceride found in a linseed oil, a triester (triglyceride) derived of linoleic acid, alpha-linolenic acid, ... Sulfuric acid is a typical catalyst for this reaction. Many other acids are also used such as polymeric sulfonic acids. Since ... Silicotungstic acid is used to manufacture ethyl acetate by the alkylation of acetic acid by ethylene: C2H4 + CH3CO2H → CH3CO2C ... Addition of carboxylic acids to alkenes and alkynes[edit]. In the presence of palladium-based catalysts, ethylene, acetic acid ...

https://en.wikipedia.org/wiki/Esters

This article is about gamma-Linolenic acid. For α-Linolenic acid, see alpha-Linolenic acid. For linoleic acid (no "n"), see ... gamma-Linolenic acid or GLA (γ-linolenic acid), (INN and USAN gamolenic acid) is a fatty acid found primarily in seed oils. ... It is an isomer of α-linolenic acid, which is a polyunsaturated n−3 (omega-3) fatty acid, found in rapeseed canola oil, ... Yung-Sheng Huang, Vincent A. Ziboh (2001). Gamma-Linolenic Acid: Recent Advances in Biotechnology and Clinical Applications. ...

https://en.wikipedia.org/wiki/Gamma-Linolenic_acid

α-Amanatin, see Alpha-amanitin. *Aimínaigéad Amino acid. *Séaróideach anabalach Anabolic steroid ... Aigéad éarúcach Erucic acid] - CH3(CH2)7CH=CH(CH2)11COOH ... Linoleic acid. *Linolenic acid. *Lipase. *Lipid. *Lipid ... Aigéad úrach Uric acid - C5H4N4O3 ... Aigéad pailmíteach Palmitic acid. *Pantothenic acid (Vitamin B5 ...

https://ga.wikipedia.org/wiki/Liosta_Bithmhóiliní

... they metabolize gamma-Linolenic acid, which has one less double bond than arachidonic acid, to series 1 prostanoids (PGD1, PGE1 ... those containing the Gs alpha subunit, Gi alpha subunit, Gq alpha subunit and/or G12 subunit;[2][4] and f) signaling pathways ... Gs alpha subunit. activates AC, increases cAMP, raises Ca2+ Prostaglandin DP2 receptor. DP2. PGD2,,PGF2α=PGE2,PGI2=TXA2[7]. ?. ... Gq alpha subunit. stimulates PLC, IP3, & PKC; raises Ca2+ Prostacyclin I2 receptor. IP. PGI2,,PGD2=PGE2=PGF2α,TXA2[13]. ...

https://en.wikipedia.org/wiki/Prostaglandin_receptor

Quinolines (e.g., 4-hydroxyquinoline, 4-hydroxyquinoline-3-carboxylic acid, 5,7-CIQA, 7-CIQ, 7-TFQ, 7-TFQA) ...

https://en.wikipedia.org/wiki/Pregnenolone

fatty acids. Smoke point Total[20]. Oleic. acid. (ω-9). Total[20]. α-Linolenic. acid. (ω-3). Linoleic. acid. (ω-6). ω-6:3. ... Another method for extraction of coconut oil involves the enzymatic action of alpha-amylase, polygalacturonases, and proteases ... Coconut oil contains lauric acid (44.6-46.7%), myristic acid (16.2-21.4%), palmitic acid (6.8-8.3%), oleic acid (7.2-9.8%), and ... In the following content, the expressions "fatty acids" and "acid" below refer to esters rather than carboxylic acids. ...

https://en.wikipedia.org/wiki/Virgin_coconut_oil

National Institute of Health (2005-08-01). "Omega-3 fatty acids, fish oil, alpha-linolenic acid". Archived from the original on ... It is ingested from oily fish, and algae oil or derived from dietary alpha-linolenic acid found in, for instance, walnuts, hemp ... Linolenic acid (18:3 ω-3) contributes to this by displacing linoleic acid (18:2 ω-6) from the elongase and desaturase enzymes ... However, the effect is not as strong; the desaturase has a higher affinity for α-linolenic acid than it has for linoleic acid. ...

https://en.wikipedia.org/wiki/Essential_fatty_acid_interactions

The major unsaturated fatty acids in soybean oil triglycerides are the polyunsaturates alpha-linolenic acid (C-18:3), 7-10%, ... Polyunsaturated fatty acids. Smoke point. Total mono[8]. Oleic acid. (ω-9). Total poly[8]. linolenic acid. (ω-3). Linoleic acid ... and linoleic acid (C-18:2), 51%; and the monounsaturate oleic acid (C-18:1), 23%.[6] It also contains the saturated fatty acids ... The high-proportion of oxidation-prone linolenic acid is undesirable for some uses, such as cooking oils. Three companies, ...

https://en.m.wikipedia.org/wiki/Soybean_oil

In the case of permethrin synthesis, the DV-acid cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, ethyl ... Numerous synthetic routes exist for the production of the DV-acid ester precursor. The pathway known as the Kuraray Process ... the final step in the total synthesis of any of the synthetic pyrethroids is a coupling of a DV-acid ester and an alcohol. ...

https://en.wikipedia.org/wiki/Permethrin

fatty acids. Polyunsaturated. fatty acids. Smoke point Total[15]. Oleic. acid. (ω-9). Total[15]. α-Linolenic. acid. (ω-3). ... Red palm oil is rich in carotenes, such as alpha-carotene, beta-carotene and lycopene, which give it a characteristic dark red ... Fatty acids[edit]. Main article: Fatty acid. Palm oil, like all fats, is composed of fatty acids, esterified with glycerol. ... Palmitic acid[edit]. Excessive intake of palmitic acid, which makes up 44% of palm oil, increases blood levels of low-density ...

https://en.wikipedia.org/wiki/Palm_oil_production

α-linolenic acid (CHEBI:27432) is a ω−3 fatty acid (CHEBI:25681) α-linolenic acid (CHEBI:27432) is a linolenic acid (CHEBI: ... α-linolenic acid (CHEBI:27432) is conjugate acid of α-linolenate (CHEBI:32387) α-linolenic acid (CHEBI:27432) is conjugate acid ... α-linolenic acid (CHEBI:27432). (R)-2-hydroperoxy-α-linolenic acid (CHEBI:76236) has functional parent α-linolenic acid (CHEBI: ... α-linolenic acid (CHEBI:27432). linolenic acid anilide (CHEBI:53751) has functional parent α-linolenic acid (CHEBI:27432). ...

https://www.ebi.ac.uk/chebi/searchId.do?chebiId=27432

... "linolic acid"; for the acid C18H30O2 [I suggest] the name "linolenic acid".) Linolenic acid is discussed on pp. 265-268. See: ... We designate this linolenic acid, which the solid hexabromide [of linolenic acid] provides, as α-linolenic acid in order to ... Thus, α-linolenic acid is a polyunsaturated n−3 (omega-3) fatty acid. It is an isomer of gamma-linolenic acid (GLA), an 18:3 (n ... "Conversion of $\alpha$-linolenic acid to longer-chain polyunsaturated fatty acids in human adults". Ramon, JM; Bou, R; Romea, S ...

https://en.wikipedia.org/wiki/Alpha-Linolenic_acid

... user ratings and products that contain Alpha-Linolenic Acid ... Learn more about Alpha-Linolenic Acid uses, effectiveness, ... Alpha-linolenic acid may not have the same benefits as EPA and DHA.. How does it work?. Alpha-linolenic acid is thought to ... Some people use alpha-linolenic acid to prevent cancer. Ironically, alpha-linolenic acid may actually raise some mens risk of ... The source of alpha-linolenic acid seems to be important. Alpha-linolenic acid from dairy and meat sources has been positively ...

https://www.webmd.com/vitamins/ai/ingredientmono-1035/alpha-linolenic-acid

... at the Schepens Eye Research Institute have found for the first time that topical drop application of alpha-linolenic acid (ALA ... 0.2 percent alpha-linolenic acid (an omega-3 fatty acid) ; 0.2 percent linoleic acid (an omega-6 fatty acid) ; and 0.1 percent ... Tags: Alpha-Linolenic Acid, Cornea, Diet, Dry Eye, Ear, Efficacy, Eye, Fatty Acids, Inflammation, Linoleic Acid, Medical School ... alpha-linolenic acid combined with 0.1 percent linoleic acid. An eye drop containing each of the three formulations was applied ...

https://www.news-medical.net/news/2008/02/12/35158.aspx

Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans.. Pawlosky RJ1, Hibbeln JR, Novotny JA ... A physiological compartmental model of alpha-linolenic acid metabolism was derived from the plasma concentration-time curves ... 5n-3 indicates that the biosynthesis of long-chain n-3 PUFA from alpha-linolenic acid is limited in healthy individuals. In ... the n-3 fatty acids in good accordance with the measured steady state concentrations and also predicted dietary linolenic acid ...

https://www.ncbi.nlm.nih.gov/pubmed/11483627

... is a type of omega-3 fatty acid that is derived from plants, and it is similar to those found in fish oil. It is found in high ... alpha-linolenic acid needs to be converted in the body into the omega-3s eicosapentaenoic acid and docosahexaenoic acid, or EPA ... Alpha-linolenic acid, or ALA, is a type of omega-3 fatty acid that is derived from plants, and it is similar to those found in ... The University of Maryland Medical Center: Alpha-linolenic Acid * British Journal of Nutrition: Omega-3 Fatty Acids and ...

https://www.livestrong.com/article/388023-what-are-the-benefits-of-alpha-linolenic-acid/

... , Atherosclerosis, Cardiovascular disease, Docosahexaenoic acid, Fatty acid, Fish oil, Omega-3 fatty acid ...

https://www.cardiobrief.org/tag/alpha-linolenic-acid/

Other: Alpha-linolenic acid Exposure to dietary intake of alpha-linolenic acid (ALA) will be assessed using a detailed food ... Background: The plant-derived omega-3 fatty acid alpha-linolenic acid (ALA, 18:3-n-3) may reduce the risk of atherosclerotic ... Alpha-linolenic Acid and the Risk of ASCVD. The safety and scientific validity of this study is the responsibility of the study ... Bork CS, Venø SK, Lundbye-Christensen S, Jakobsen MU, Tjønneland A, Schmidt EB, Overvad K. Dietary Intake of α-Linolenic Acid ...

https://clinicaltrials.gov/ct2/show/NCT03258983?term=ALA&rank=32

Omega-3 (n-3) fatty acids can be divided into alpha-linolenic acid (ALA; C18:3n-3) from plant origin, and eicosapentaenoic acid ... For alpha-linolenic acid (ALA), which is the omega-3 fatty acid from plants, the relation to cardiovascular health is less ... Wang C, Harris WS, Chung M, et al.: n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefit ... Egert S, Kannenberg F, Somoza V, et al.: Dietary alpha-linolenic acid, EPA, and DHA have differential effects on LDL fatty acid ...

https://link.springer.com/article/10.1007/s11883-010-0137-0?error=cookies_not_supported&code=8763afe8-79c5-4098-93c8-c014a95b0db1

Alpha-Linolenic Acid*Casein*Dextrins*Lactose*L-Carnitine*Linoleic Acid (Vegetable Fat)*Moisture*Multiminerals*Multivitamins* ... Alpha-Linolenic Acid 0.37 g; Casein 4.5 g; Dextrins 25.2 g; Lactose 33.7 g; L-Carnitine; Linoleic Acid (Vegetable Fat) 3.7 g; ...

https://drugs-about.com/drugs-b/bebelac-ec.html

Dietary chia seed (Salvia hispanica L.) rich in alpha-linolenic acid improves adiposity and normalises ... rich in alpha-linolenic acid and fibre upon dyslipidaemia and insulin resistance (IR), induced by intake of a sucrose-rich ( ...

https://www.greenmedinfo.com/article/dietary-chia-seed-s-hispanica-improves-adiposity-and-normalizes-high-triglycer

Prostaglandins Leukot Essent Fatty Acids. 2013 Jan;88(1):139-46. doi: 10.1016/j.plefa.2012.04.003. Epub 2012 Apr 17. ... Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids.. Gibson RA1 ... α-linolenic acid (ALA, 18:3n-3) to the long-chain eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) ... total fatty acids) at dietary intakes of total polyunsaturated fatty acids (PUFA) above 3 en%. We conclude it is possible to ...

https://www.ncbi.nlm.nih.gov/pubmed/22515943

Alpha-Linolenic Acid*Beta-Carotene*Calcium*Carbohydrates*Carbon Black*Chloride*Choline*Copper*Cytidine Monophosphate*Fat*Folic ... Powder for Suspension; Oral; Adenosine Monophosphate 3.7 mg; Alpha-Linolenic Acid 485 mg; Beta-Carotene 310 mcg; Calcium 385 mg ... Folic Acid 80 mcg; Guanosine Monophosphate 2.6 mg; Inosine Monophosphate 1.6 mg; Iodine 54 mcg; Iron 6 mg; Linoleic Acid 3.4 g ... Linoleic Acid*Magnesium*Manganese*Phosphorus*Potassium*Protein*Sodium*Taurine*Uridine Monophosphate*Vitamin A (Retinol)*Vitamin ...

http://drugs-about.com/drugs-f/frisolac-frieslandcampina.html

PubMed journal article Adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction in Costa Ric were found in ... between alpha-linolenic acid and nonfatal acute MI suggests that consumption of vegetable oils rich in alpha-linolenic acid ... between alpha-linolenic acid and nonfatal acute MI suggests that consumption of vegetable oils rich in alpha-linolenic acid ... Alpha-linolenic acid may protect against cardiovascular disease. We examined the association between adipose tissue alpha- ...

https://www.unboundmedicine.com/medline/citation/12668490/Adipose_tissue_alpha_linolenic_acid_and_nonfatal_acute_myocardial_infarction_in_Costa_Rica_

Dihomo-gamma-linolenic acid. Fatty acid elongase. FADS2. Arachidonic acid. Linoleic acid. gamma-Linolenic acid. FADS1. ... Fatty acid elongase. Protein. Q61527727 (Wikidata) Linoleic acid. Metabolite. CHEBI:6479 (ChEBI) gamma-Linolenic acid. ... Metabolism of alpha-linolenic acid (Homo sapiens). From WikiPathways. Revision as of 10:30, 6 May 2019 by Chris (Talk , ... Arachidonic acid. Metabolite. CHEBI:2799 (ChEBI) Dihomo-gamma-linolenic acid. Metabolite. Q415398 (Wikidata) FADS1. GeneProduct ...

https://www.wikipathways.org/index.php?title=Pathway:WP4586&oldid=104119

Arachidonic acid. FADS1. alpha-Linolenic acid. eicosapentaenoic acid. docosahexaenoic acids. Elongase. FADS2. FADS2. FADS1. ... Linoleic acid. gamma-Linolenic acid. Dihomo-gamma-linolenic acid. 15-HEPE. Arachidonic acid 5-hydroperoxide. 12-HPEPE. 15-HETE ... Metabolism of alpha-linolenic acid and linoleic acid to their respective acids. Both of these processes are catalyzed primarily ... alpha-Linolenic acid. Metabolite. CHEBI:27432 (ChEBI) docosahexaenoic acids. Metabolite. CHEBI:36005 (ChEBI) eicosapentaenoic ...

https://www.wikipathways.org/index.php?title=Pathway:WP4586&oldid=104629

Small Entity Compliance Guide: Alpha-Linolenic Acid, Eicosapentaenoic Acid, and Docosahexaenoic Acid Omega-3 Fatty Acids ... Small Entity Compliance Guide: Alpha-Linolenic Acid, Eicosapentaenoic Acid, and Docosahexaenoic Acid Omega-3 Fatty Acids ... Alpha-Linolenic Acid, Eicosapentaenoic Acid, and Docosahexaenoic Acid Omega-3 Fatty Acids" ("the rule"). ... One notification concerning nutrient content claims for Alpha-Linolenic Acid (ALA), Docosahexaenoic Acid (DHA), and ...

https://www.fda.gov/regulatory-information/search-fda-guidance-documents/small-entity-compliance-guide-alpha-linolenic-acid-eicosapentaenoic-acid-and-docosahexaenoic-acid

Dietary alpha-linolenic acid intake and risk of sudden cardiac death and coronary heart disease. Download Prime PubMed App to ... Alpha-linolenic acid, an intermediate-chain n-3 fatty acid found primarily in plants, may decrease the risk of fatal coronary ... The specificity of the association between alpha-linolenic acid and SCD supports the hypothesis that these n-3 fatty acids may ... The specificity of the association between alpha-linolenic acid and SCD supports the hypothesis that these n-3 fatty acids may ...

https://www.unboundmedicine.com/medline/citation/16301356/Dietary_alpha_linolenic_acid_intake_and_risk_of_sudden_cardiac_death_and_coronary_heart_disease_

... is the most commo n omega-3 fatty acid i n the Wester n diet. The relatio n of dietary i ntake of ALA to prostate ca ncer risk ... Alpha-linolenic acid (ALA) is the most common omega-3 fatty acid in the Western diet. The relation of dietary intake of ALA to ... Attar-Bashi, NM, Frauman, AG, Sinclair, AJ 2004Alpha-linolenic acid and the risk of prostate cancer. What is the evidence?J ... De Stefani, E, Deneo-Pellegrini, H, Boffetta, P, Ronco, A, Mendilaharsu, M 2000Alpha-linolenic acid and risk of prostate cancer ...

https://link.springer.com/article/10.1007%2Fs10552-006-0014-x

Here, we analyzed the impact of dietary omega-3 alpha-linolenic fatty acid from linseed oil on skeletal muscle telomere biology ... Linseed-oil-supplemented animals showed an increased level of alpha-linolenic acid in skeletal muscles compared to control ... Our results suggest that omega-3 linolenic acid counteracts the elevation of TRF1 levels, which increase with age and due to ... Recent studies have reported the role of these fatty acids in the aging process, explicitly impacting telomere biology. The ...

https://www.mdpi.com/2076-2615/10/6/1090

... formation from alpha-linolenic acid (ALA) involves peroxisomal oxidation of 24:6n-3 to DHA. The aim of the study was to ... determine whether conjugated linoleic acid (CLA) would enhance conversion of ALA to DHA in humans on an ALA-supplemented diet. ... A rate-limiting step in docosahexaenoic acid (DHA) ... alpha-Linolenic Acid / metabolism * alpha-Linolenic Acid / ... Failure of Conjugated Linoleic Acid Supplementation to Enhance Biosynthesis of Docosahexaenoic Acid From Alpha-Linolenic Acid ...

https://pubmed.ncbi.nlm.nih.gov/17275274/

Vitamin A deficiency reduces liver and colon docosahexaenoic acid levels in rats fed high linoleic and low alpha-linolenic acid ... Vitamin A deficiency reduces liver and colon docosahexaenoic acid levels in rats fed high linoleic and low alpha-linolenic acid ... The VAD compared to the VAS rats had elevated levels of arachidonic (AA, P,0 .001), adrenic acid (22:4 omega 6, P,0.005) and OA ... After seven weeks of feeding, the rats were killed and colon and liver tissues removed for the analysis of fatty acids and ...

https://www.fabresearch.org/viewItem.php?id=8258&listId=5374&categoryId=&navPageId=978

Long-term effects of dietary alpha-linolenic acid from perilla oil on serum fatty acids composition and on the risk factors of ... Long-term effects of dietary alpha-linolenic acid from perilla oil on serum fatty acids composition and on the risk factors of ... Long-term effects of dietary alpha-linolenic acid from perilla oil on serum fatty acids composition and on the risk factors of ... Long-term effects of dietary alpha-linolenic acid from perilla oil on serum fatty acids composition and on the risk factors of ...

http://agris.fao.org/agris-search/search.do?recordID=JP2000005096

Intake of alpha-linolenic, but not of docosahexaenoic acid (DHA) correlates positively with DHA content and with parameters for ... "Intake of Alpha-linolenic, but Not of Docosahexaenoic Acid (DHA) Correlates Positively with DHA Content and with Parameters for ... "Intake of Alpha-linolenic, but Not of Docosahexaenoic Acid (DHA) Correlates Positively with DHA Content and with Parameters for ... Christophe A, ZALATA A, MAHMOUD M, Comhaire F. Intake of alpha-linolenic, but not of docosahexaenoic acid (DHA) correlates ...

https://biblio.ugent.be/publication/114167

Udos 369 Oil Blend is a special blend of carefully chosen, natural, unrefined, Essential Fatty Acid-rich oils the good fats. ... The two from fats are the essential fatty acids. One is alpha-linolenic acid (omega 3): the other is linoleic acid (omega 6). ... Contains 60% Omega 3 as Alpha Linolenic acid (ALA). This product is non GMO. ... Udos 369 Oil Blend is a special blend of carefully chosen, natural, unrefined, Essential Fatty Acid-rich oils the good fats. ...

https://www.healthy.co.nz/product/3404-udos-oil-369.html

EPA and DHA are found in animal fat and are quite expensive compared to their precursor alpha-linolenic acid (alpha-LNA) found ... In contrast to AA, which is an omega-6 fatty acid, the omega-3 fatty acids, after having been liberated from the cell membrane ... Dietary supplementation with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) has therefore been used to decrease the ... AA, EPA and DHA did not change either in spite of a significant increase in alpha-LNA in the treatment group. Thus, 3-months ...

https://www.semanticscholar.org/paper/Alpha-linolenic-acid-in-the-treatment-of-rheumatoid-Nordstr%C3%B6m-Friman/ac8370fb236e6eaf8b731b256559d3cc3eac44c2

Erratum to: Effects of alpha-linolenic acid vs. docosahexaenoic acid supply on the distribution of fatty acids among the rat ... Effects of alpha-linolenic acid vs. docosahexaenoic acid supply on thedistribution of fatty acids among the rat cardiac ... Table 1 Formulation and fatty acid composition of the experimental diets.. Full size table ... An overlapping of the lines has occurred in the fatty acid profile section of the Table, due to an unfortunate insertion of the ...

https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-6-35

... labeled linoleic acid ([13C]LA)- and alpha-linolenic acid ([13C]ALA)-methylesters. Regulative cellular signal transduction ... and alpha-linolenic acid (ALA) to their higher chain homologues in humans depends on the ratio of ingested n6 and n3 fatty ... In order to determine the most effective ratio with regard to the conversion of ALA to eicosapentaenoic acid (EPA) and ... Also, our findings suggest that a diet-induced enhancement of the cell membrane content of highly unsaturated fatty acids is ...

https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-6-8

alpha-linolenic acidarachidonic acidDHAdihomo-gamma-linolenic acidEPAessential fatty acidsgamma-linolenic acidlinoleic acid ... alpha-linolenic acidcholesterolDHAEPAessential fatty acidslinoleic acidomega-3 fatty acidsomega-6 fatty acidspolyunsaturated ... Like linoleic acid (omega-6 fatty acid), alpha-linolenic acid or ALA is a primary product of plant polyunsaturated fatty acid ... alpha-linolenic acidcardiovascular diseasecholesterolelaidic acidfatslipidspolyunsaturated fatty acidssaturated fatty acids ...

http://www.tuscany-diet.net/tag/alpha-linolenic-acid/

... is a type of omega-3 fatty acid found in plants. It is found in flaxseed oil, and in ... Researchers dont know whether alpha-linolenic acid supplements would have the same benefits as foods with alpha-linolenic acid ... which is high in alpha-linolenic acid, have been mixed. Some studies found that alpha-linolenic acid may help lower cholesterol ... Note: Alpha-linolenic acid is not the same as alpha-lipoic acid, an antioxidant that helps the body turn glucose into energy. ...

http://nch.adam.com/content.aspx?productid=107&isarticlelink=false&pid=33&gid=000284

The word linolenic is an irregular derivation from linoleic, which itself is derived from the Greek word linon (flax). (wikipedia.org)
Oleic means "of or relating to oleic acid" because saturating linoleic acid's omega-6 double bond produces oleic acid. (wikipedia.org)
Although the best source of ALA is seeds, most seeds and seed oils are much richer in an n−6 fatty acid, linoleic acid. (wikipedia.org)
Linoleic acid is the other essential fatty acid, but it, and the other n−6 fatty acids, compete with n−3s for positions in cell membranes and have very different effects on human health. (wikipedia.org)
DuPont's effort involves silencing the FAD2 gene that codes for Δ6-desaturase, giving a soy oil with very low levels of both α-linolenic acid and linoleic acid. (wikipedia.org)
Preliminary clinical research suggests alpha-linolenic acid, in combination with linoleic acid, might reduce the number of respiratory infections in children. (webmd.com)
and 0.1 percent alpha-linolenic acid combined with 0.1 percent linoleic acid. (news-medical.net)
The present study evaluates means of maximizing plasma DHA accumulation by systematically varying both linoleic acid (LA, 18:2n-6) and ALA dietary level. (nih.gov)
Metabolism of alpha-linolenic acid and linoleic acid to their respective acids. (wikipathways.org)
Studies in normal healthy adults consuming western diets, which are rich in linoleic acid (LA), show that supplemental ALA raises EPA and DPA status in the blood and in breast milk. (nih.gov)
Although many factors, such as genetic polymorphisms, influence the expression and activities of the enzymes involved in the conversion of ALA to DHA, one reason for the poor conversion is believed to be the relatively high level of linoleic acid (LA) present in the average Westernized diet consumed today by a large proportion of people worldwide. (fatsoflife.com)
HCE cells were incubated for 2 hours with different concentrations of PUFAs: alpha-linolenic acid (ALA), gamma-linolenic acid (GLA), and linoleic acid (LA). Oleic acid (OA) and dexamethasone (DM) served as negative and positive controls, respectively. (arvojournals.org)
One is alpha-linolenic acid (omega 3): the other is linoleic acid (omega 6). (healthy.co.nz)
Low zinc intake increases apparent oxidation of linoleic and alpha-linolenic acids in the pregnant rat. (semanticscholar.org)
Serum linoleic and total polyunsaturated fatty acids in relation to prostate and other cancers: a population-based cohort study. (semanticscholar.org)
Conversion of linoleic acid (LA) and alpha-linolenic acid (ALA) to their higher chain homologues in humans depends on the ratio of ingested n6 and n3 fatty acids. (biomedcentral.com)
An essential fatty acid alpha-Linolenic acid (Not to be confused with linoleic acid) is an organic compound found in many common vegetable oils. (foodb.ca)
Additive anti-inflammation by a combination of conjugated linoleic acid and α-lipoic acid. (greenmedinfo.com)
RISHON supplies pure natural Sea buckthorn pulp oil made by cold press, and it is rich in unsaturated fatty acids as alpha linolenic acid (ALA), linolenic acid & linoleic acid which are very important for human health. (viprole.com)
For linoleic acid (no "n"), see linoleic acid . (wikipedia.org)
The human body produces GLA from linoleic acid (LA). This reaction is catalyzed by Δ 6 - desaturase (D6D), an enzyme that allows the creation of a double bond on the sixth carbon counting from the carboxyl terminus. (wikipedia.org)
Semiochemical - linoleic acid Species utilize (Z,Z)-9,Octadecadienoic acid in its chemical communication system. (ibac2017india.com)
Montes de Toledo designation of origin olive oil has high oleic acid content, a low linoleic acid content and a high total polyphenol content, giving it great stability. (ibac2017india.com)
Enrichment of conjugated linoleic acid. (ibac2017india.com)
Conjugated linoleic acid (CLA) is a mixture of linoleic acid chemical communication system of CLA or vaccenic acid. (ibac2017india.com)
Ainakin viel eilen puoluejohtaja Osmo harrastustoiminnan rajoittamista selvitelln, kommentoi Linoleic Acid vaivaa nhnyt, Hsl Kadonneet Tavarat viesti piti pist. (ibac2017india.com)
Linoleic Acid Get FREE Access! (ibac2017india.com)
They examined the studies and unesterified linoleic acid concentration increases following a brain injury, which suggests that linoleic acid or its metabolites may be involved in the natural response to injuries involving the brain. (ibac2017india.com)
Animal studies indicate that this acid may be involved in a group of conjugated octadecadienoic hempand many common from linoleic acid. (ibac2017india.com)
Linoleic acid is a fatty seeds and oils, including flaxseedwalnutschiaacid isomers that are derived. (ibac2017india.com)
Continue to avoid eating too acid that functions as an low concentrations of linoleic acid. (ibac2017india.com)
Hilditch and others in-Linoleic acid, cis -9, cis. (ibac2017india.com)
Linoleic Acid is particularly helpful for the skin and is sometimes mistaken as an essential fatty acid. (aromaweb.com)
Linoleic Acid (C18:2) is a polyunsaturated omega-6 fatty acid. (aromaweb.com)
In recent years, conjugated linoleic acid has gained many fans among the fitness-minded. (oxygenmag.com)
The body needs fatty acids to survive and is able to make all but two of them: linoleic acid (LA), in the omega-6 family, and alpha-linolenic acid (ALA) in the omega-3 family. (prohealth.com)
[ 1 ] The polyunsaturated fatty acids were primarily comprised of linoleic and alpha-linolenic acids. (globalhealingcenter.com)
Let's start by taking a look at how linoleic and alpha-linolenic fatty acids have been identified as essential to health. (globalhealingcenter.com)
Studies have shown linoleic acid (an omega-6 fatty acid) occurs naturally, in hefty amount, in hemp seed. (globalhealingcenter.com)
Linoleic acid contributes to radiant skin, liver and kidney function, hair growth, proper immune function and cardiovascular health. (globalhealingcenter.com)
Pasture and dietary lipid supplementation have been reported to be reliable strategies in ruminant nutrition, in order to increase the content of α-linolenic acid (ALA), conjugated linoleic acid (CLA) and vaccenic acid (VA), and decrease SFA in milk fat. (cambridge.org)
a derivative of linoleic acid. (yogajournal.com)
[1] The vast majority (89%) of the polyunsaturated fat consumed is linoleic acid , an omega-6 fatty acid, compared to only 9%-11% from alpha-linoleic acid (ALA), an omega-3. (sourcewatch.org)
The study estimated per capita linoleic acid (omega-6) consumption at 11-16g/day. (sourcewatch.org)
These same enzymes are used in a parallel process converting the omega-6 fatty acid linoleic acid (LA) (18:2n-6) to longer chain, highly unsaturated fatty acids. (sourcewatch.org)
Only two fatty acids are known to be essential for humans: alpha-linolenic acid (an omega-3 fatty acid) and linoleic acid (an omega-6 fatty acid). (wikipedia.org)
Both the essential fatty acids are SC-PUFA with an 18-carbon chain: ω-3 fatty acid: α-linolenic acid or ALA (18:3n-3) ω-6 fatty acid: linoleic acid or LA (18:2n-6) These two fatty acids cannot be synthesized by humans because humans lack the desaturase enzymes required for their production. (wikipedia.org)

The conversion of arachidonic acid to prostanoids is catalysed by prostaglandin G/H synthase 2 and the conversion of arachidonic acid to lipoxins is catalysed by different types of lipoxygenases. (wikipathways.org)
In rheumatoid arthris s various pro-inflammatory metabolites of arachidonic acid (AA), such as leukotriene B4 (LTB4) and prostaglandin E2 (PGE2), contribute to tissue destruction and pain. (semanticscholar.org)
Corticosteroids inhibit formation of arachidonic acid from phospholipids when cell membranes are damaged. (thefreedictionary.com)
When acting on GLA, arachidonate 5-lipoxygenase produces no leukotrienes and the conversion by the enzyme of arachidonic acid to leukotrienes is inhibited. (wikipedia.org)
Arachidonic acid (AA) tends to be unhealthy because it is the precursor of inflammatory eicosanoids - such as prostaglandin E2 (PGE2), thromboxane A2, and leukotriene B4 - which promote inflammation. (prohealth.com)
Sesame lignans not only increase beneficial DGLA but they also impede the conversion of GLA into the proinflammatory mediator arachidonic acid. (prohealth.com)
What Is Arachidonic Acid? (glutenfreeworks.com)
Arachidonic acid is a major essential (must have/can't make) omega-6 fatty acid. (glutenfreeworks.com)
Rishon Biochem Co., Ltd is a professional supplier of vegetarian source omega-3,6 essential unsaturated fatty acids,include Docosahexaenoic Acid (DHA), Eicosapentaenoic Acid (EPA), Arachidonic Acid (AA or ARA), -Linolenic acid, Alpha linolenic acid (ALA).RISHON is dedicated to improve People living quality and environment, we mainly work on researching and producing of Health Food and related products. (rishonbiochem.com)
This is elongated by elongase to 20:3n-6 and then desaturated once again using delta-5-desaturase to arachidonic acid 20:4n-6. (sourcewatch.org)

It is an isomer of gamma-linolenic acid (GLA), an 18:3 (n−6) fatty acid (i.e., a polyunsaturated omega-6 fatty acid with three double bonds). (wikipedia.org)
gamma-Linolenic acid or GLA ( γ-linolenic acid ), ( INN and USAN gamolenic acid ) is a fatty acid found primarily in seed oils. (wikipedia.org)
In contrast, gamma-linolenic acid (GLA), found in evening primrose oil, borage oil, and black currant oil, is an important fatty acid that plays a beneficial role in healthy prostaglandin (PGE1) formation and pro-inflammatory mediator reduction. (prohealth.com)
Health-conscious people have been swallowing a lot of borage oil supplements to obtain GLA (gamma linolenic acid), the parent of the biologically active DGLA (dihomogamma linolenic acid). (prohealth.com)
Delta-6-desaturase first converts LA to gamma-linolenic acid (GLA) (18:3n-6). (sourcewatch.org)
examples include docosahexaenoic acid (an omega-3 fatty acid) and gamma-linolenic acid (an omega-6 fatty acid). (wikipedia.org)

Omega-3s, and therefore alpha-linolenic acid, help to control blood clotting, build cell membranes in the brain and reduce inflammation. (livestrong.com)
Omega-3 fatty acids can modulate the expression of a number of genes, including those involved with fatty acid metabolism and inflammation. (hmdb.ca)
It is believed that omega-3 fatty acids may help lower triglycerides and inflammation. (goodearthnaturalfoods.com)
Extensive research indicates that omega-3 fatty acids reduce inflammation and help prevent risk factors associated with chronic diseases such as heart disease, cancer, and arthritis. (nutritionvista.com)
Putting test subjects on a diet high in Alpha-Linolenic Acid, an omega-3 fatty acid (17% of calories from these polyunsaturated fatty acids) decreased inflammation-causing substances in the body and also decreased total cholesterol, LDL-cholesterol and triglycerides. (invitehealth.com)
Omega-3 fatty acids -- especially EPA and DHA -- have been shown to reduce inflammation and may help prevent chronic diseases, such as heart disease and arthritis. (adam.com)
Preliminary research suggests that omega-3 fatty acid supplements (particularly perilla seed oil, which is rich in alpha-linolenic acid) may decrease inflammation and improve lung function in some people with asthma. (adam.com)
Alpha-linolenic acid given as an anti-inflammatory agent in a mouse model of colonic inflammation. (greenmedinfo.com)
It is an omega-3 fatty acid that can reduce symptoms of depression and help fight inflammation in the body. (healthline.com)
Flaxseed oil is rich in essential fatty acids that help decrease inflammation and may improve symptoms of arthritis in the knees. (livestrong.com)
A study published in the February 2008 issue of the "American Journal of Clinical Nutrition" found that omega-3 and omega-6 fatty acids in flax oil decrease inflammation in chronic conditions such as asthma, allergy and cardiovascular disease. (livestrong.com)
Inflammation in schizophrenia, Parkinson's disease and Alsheimer's disease could be due to low levels of taurine which leads to failures to absorb sufficient fatty acids with inflammation resulting. (schizepigenetics.com)
Omega-3 fatty acids help reduce inflammation in the body and can also lower risk factors related to heart disease and arthritis. (nootriment.com)
6 ] Finally, this fatty acid has been shown to decrease inflammation in the lungs and improve breathing in individuals with asthma. (nootriment.com)
N-3 polyunsaturated fatty acids: relationship to inflammation in healthy adults and adults exhibiting features of metabolic syndrome. (globalhealingcenter.com)
The effect of alpha linolenic acid on tracheal responsiveness, lung inflammation, and immune markers in sensitized rats. (flaxresearch.com)
N-3 polyunsaturated fatty acids (PUFAs) have been associated with reduced inflammation. (nature.com)

Prostaglandins Leukot Essent Fatty Acids. (nih.gov)

The capacity for conversion of α-linolenic acid (ALNA) to n −3 long-chain polyunsaturated fatty acids was investigated in young men. (cambridge.org)
In free fatty acid form, the chemical structure of stearidonic acid is: Polyunsaturated fatty acids with 16-carbon and 18-carbon chains are sometimes classified as short chain polyunsaturated fatty acids (SC-PUFA), as opposed to long-chain polyunsaturated fatty acids (LC-PUFA), which have more than 18 carbon atoms. (wikipedia.org)

However, when partially hydrogenated, part of the unsaturated fatty acids become unhealthy trans fats. (wikipedia.org)
In a nut-shell, one of the best ways to help prevent and treat heart disease is to eat a low-fat diet and to replace foods rich in saturated and trans-fat with those that are rich in monounsaturated and polyunsaturated fats (including omega-3 fatty acids). (nutritionvista.com)
Udo's 369 Oil Blend is a special blend of carefully chosen, natural, unrefined, Essential Fatty Acid-rich oils the good fats. (healthy.co.nz)
Two come from fats and oils (The other 48 are vitamins, minerals, and essential amino acids from proteins). (healthy.co.nz)
The two from fats are the essential fatty acids. (healthy.co.nz)
Trans fatty acids (TFA) or trans -unsaturated fatty acids or trans fats are unsaturated fatty acids with at least one a double bond in the trans or E configuration . (tuscany-diet.net)
This means that trans fatty acids contribute, together with the geometrically similar saturated fatty acids , to the hardness of the fats in which they are, giving them a higher melting point . (tuscany-diet.net)
Note: trans fats tend to be less solid than saturated fatty acids . (tuscany-diet.net)
The term trans fatty acids or trans fats appeared for the first time in the Remark column of the 5th edition of the "Standard Tables of Food Composition" in Japan. (tuscany-diet.net)
One of the best ways to help prevent and treat heart disease is to eat a diet that is low in saturated and trans fats, and rich in monounsaturated and polyunsaturated fats, particularly omega-3 fatty acids. (adam.com)
Omega-3 fatty acids are essential fats that have numerous benefits for health. (healthline.com)
Omega-3 fatty acids are a group of polyunsaturated fats that we must get from the diet. (healthline.com)
Omega-3 and omega-6 fatty acids are polyunsaturated fats whereas omega-9 is a monounsaturated fat. (nootriment.com)
Further, a 2013 study in The American Journal of Clinical Nutrition reported that replacing some of the palmitic acid, the main saturated fat found in dairy, beef and other animal-based foods, with monounsaturated fats like oleic acid can increase resting energy expenditure, which may help you ditch some of that extra padding on your midriff. (oxygenmag.com)
Brief Summary: Omega-3 fatty acids are "good fats," and are among the most important nutrients lacking in Western diets today. (shine.com)
Omega-3 Fatty Acids (Omega-3s) are polyunsaturated fats with a double bond at the third carbon atom from the end of the carbon chain. (sourcewatch.org)
Omega-3, omega-6 and omega-9 fatty acids are all important dietary fats. (healthline.com)
Omega-3 fatty acids are polyunsaturated fats, a type of fat your body can't make. (healthline.com)
The term "essential fatty acid" refers to fatty acids required for biological processes but does not include the fats that only act as fuel. (wikipedia.org)

Research therefore suggests the beneficial effects of alpha-linolenic acid may be less pronounced than the benefits from taking omega-3s derived from animal sources. (livestrong.com)

Because the efficacy of n−3 long-chain polyunsaturated fatty acid (LC-PUFA) synthesis decreases down the cascade of α-linolenic acid conversion, DHA synthesis from α-linolenic acid is even more restricted than that of EPA. (wikipedia.org)
The inefficiency of the conversion of 18:3n-3 to 20:5n-3 indicates that the biosynthesis of long-chain n-3 PUFA from alpha-linolenic acid is limited in healthy individuals. (nih.gov)
alpha-Linolenic acid (ALA) is a polyunsaturated fatty acid (PUFA). (hmdb.ca)
Blood levels of polyunsaturated fatty acids (PUFA) are considered biomarkers of status. (nih.gov)
Alpha-linolenic acid, ALA, the plant omega-3, is the dietary precursor for the long-chain omega-3 PUFA eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA). (nih.gov)
Statistically significant inverse associations were also observed with the total serum long-chain n-3 PUFA concentration and with the individual long-chain n-3 PUFAs docosapentaenoic acid and docosahexaenoic acid, but not with eicosapentaenoic acid or with the intermediate-chain n-3 PUFA alpha-linolenic acid. (nature.com)

Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. (greenmedinfo.com)

Unfortunately, alpha-linolenic acid needs to be converted in the body into the omega-3s eicosapentaenoic acid and docosahexaenoic acid, or EPA and DHA, in order for it to be effective. (livestrong.com)
A raft of research papers have shown that people who take in higher amounts of the omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid have improved heart, joint, brain, immune and eye health. (oxygenmag.com)
1,3 These effects can be achieved directly by α-linolenic acid 3,7 or through conversion to long-chain n-3 fatty acids, including eicosapentaenoic acid and docosahexaenoic acid. (ahajournals.org)

Systemic polyunsaturated fatty acids (PUFAs) were shown to improve the symptoms of dry eye syndrome due to their anti-inflammatory effects. (arvojournals.org)
The specific members of this group are called polyunsaturated fatty acids, or PUFAs. (whfoods.com)
The two major classes of polyunsaturated fatty acids (PUFAs) are the omega-3 and omega-6 fatty acids. (viprole.com)
Like all fatty acids, PUFAs consist of long chains of carbon atoms with a carboxyl group at one end of the chain and a methyl group at the other. (viprole.com)

Supplementation with alpha-linolenic acid-rich diacylglycerol suppresses fatty liver formation accompanied by an up-regulation of beta-oxidation in Zucker fatty rats. (biomedsearch.com)
The overall conclusion was that EPA + docosahexaenoic acid (DHA) and/or ALA supplementation at low doses did not reduce the occurrence of major cardiovascular events in patients with a previous myocardial infarction who were receiving good clinical care. (biomedcentral.com)
Alpha linolenic fatty acid supplementation had a beneficial effect on tumor cell proliferation and cachexia parameters. (greenmedinfo.com)
Alpha-linolenic acidbut supplementation improves endothelial dysfunction and diminishes experimental hypertension. (greenmedinfo.com)
In another study, supplementation with perilla seed oil, which is one of the best sources of alpha-linolenic acid , was found to improve symptoms in some asthma sufferers. (healwithfood.org)
There are few side effects associated with alpha linolenic acid supplementation, but some precautions may be necessary for certain individuals. (nootriment.com)
U.S., Feb. 9 -- ClinicalTrials.gov registry received information related to the study (NCT03040856) titled 'The Effect of Alpha Linolenic Acid (ALA) Supplementation During Pregnancy' on Feb. 1. (shine.com)
In all study patients being treated for acne, lesion counts will be assessed and evaluated for any differences between patients on omega-3 fatty acid supplementation and not on supplementation. (clinicaltrials.gov)
Patients with a history of adverse reaction to omega-3 fatty acid supplementation. (clinicaltrials.gov)

Although alpha-linolenic acid seems to benefit the cardiovascular system and might reduce the risk of heart disease, research to date does not show it has a significant effect on cholesterol levels. (webmd.com)
α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis. (greenmedinfo.com)
Alpha-linolenic acid intake confers protection against cardiovascular disease. (greenmedinfo.com)
Alpha-linolenic acid has been found to be beneficial for the prevention and treatment of a variety of cardiovascular disorders including heart attacks and stroke. (livestrong.com)
Background: The plant-derived omega-3 fatty acid alpha-linolenic acid ( ALA , 18:3-n-3) may reduce the risk of atherosclerotic cardiovascular disease, including incident myocardial infarction, ischemic stroke and peripheral artery disease. (clinicaltrials.gov)
Alpha-Linolenic Acid: Is It Essential to Cardiovascular Health? (springer.com)
For alpha-linolenic acid (ALA), which is the omega-3 fatty acid from plants, the relation to cardiovascular health is less clear. (springer.com)
The IOM noted that intakes of n-3 fatty acids above the AI may confer additional health benefits, especially with respect to cardiovascular health. (springer.com)
Alpha-linolenic acid may protect against cardiovascular disease. (unboundmedicine.com)
The inverse association observed between alpha-linolenic acid and nonfatal acute MI suggests that consumption of vegetable oils rich in alpha-linolenic acid confers important protection against cardiovascular disease. (unboundmedicine.com)
We previously reported that a diet high in alpha-linolenic acid (ALA) reduces lipid and inflammatory cardiovascular disease risk factors in hypercholesterolemic subjects. (nih.gov)
Increased postprandial plasma triacylglycerol (TAG) levels have been shown to increase the risk of cardiovascular disease (CVD) in women more than in men [ 1 ], and since most of the day is spent in the postprandial state, it is important to characterize the ways in which different dietary fatty acids (FAs) influence postprandial lipaemia. (biomedcentral.com)
Although the strength of the evidence is not nearly the same as for marine omega-3 fatty acids, there has been an increase in the number of studies that support the idea that ALA is good for the cardiovascular system. (healwithfood.org)
There is also evidence that omega-3 fatty acid and alpha-linolenic acid benefits can improve cardiovascular health and reduce risk factors for strokes, heart attacks, and high blood pressure. (nootriment.com)
Additional studies have looked at the benefits of alpha linolenic acid for reducing blood pressure - a significant risk factor in cardiovascular disease. (nootriment.com)
During the first 3 years of follow-up, patients took part in a randomized, double-blind and placebo-controlled trial (Alpha Omega Trial) to test the effect of low doses of omega-3 fatty acids on major cardiovascular events. (alphaomegacohort.org)
Linseed oil is considered to be nature's richest source of .omega-3 fatty acids may support cardiovascular health. (physiciannaturals.com)
Background- α-Linolenic acid may protect against cardiovascular disease. (ahajournals.org)
Vitamin E provides important antioxidant effects for polyunsaturated fatty acids (the omega-3s and -6s) as it protects them from oxidation and supports cardiovascular health. (globalhealingcenter.com)

Some research suggests alpha-linolenic acid has a greater effect on coronary heart disease when intake of fish oils is low. (webmd.com)
Alpha-linolenic acid, an intermediate-chain n-3 fatty acid found primarily in plants, may decrease the risk of fatal coronary heart disease (CHD) through a reduction in fatal ventricular arrhythmias and sudden cardiac death (SCD). (unboundmedicine.com)
Omega-3 fatty acids are thought to provide a wide range of health benefits, including a lower risk of coronary heart disease and improvement in cholesterol. (goodearthnaturalfoods.com)
Although important roles of dietary n-3 fatty acids in the revention of coronary heart disease (CHD) have been suggested, long-term effects of dietary alpha-linolenic acid (ALA, 18:3/3n-3) have not yet been established under controlled conditions. (fao.org)
Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. (semanticscholar.org)
Alpha-Linolenic acid is hypothesized to reduce the risk of coronary heart disease (CHD) 1-3 and was found to be beneficial in secondary prevention trials. (ahajournals.org)

In contrast to AA, which is an omega-6 fatty acid, the omega-3 fatty acids, after having been liberated from the cell membrane phospholipids, are further converted into the non-or anti-inflammatory eicosanoids LTB5 and PGI3. (semanticscholar.org)
Fish oil capsules and fish supplying EPA and DHA, two omega-3 fatty acids have a variety of anti-inflammatory and immune-modulating (immune controlling) effects that may be relevant to hardening of the arteries and its risk of heart attack, stroke, and sudden death. (invitehealth.com)
With this 10:1 ratio of dietary n6 to n3 LCPUFA, the formation of pro-inflammatory/aggregatory eicosanoids from LA is favored over those from n3 fatty acids showing anti-inflammatory/aggregatory effects. (biomedcentral.com)
Alpha-linolenic acid protects against lipopolysaccharide-induced acute lung injury through anti-inflammatory and anti-oxidative pathways. (greenmedinfo.com)
Although GLA is an n −6 fatty acid, a type of acid that is, in general, pro-inflammatory, it has anti-inflammatory properties. (wikipedia.org)
Alpha-linolenic acid is a carboxylic acid, whose anti-inflammatory and anti-oxidant effects are shown in various studies. (cu.edu.tr)

Certain nuts (English walnuts) and vegetable oils (canola, soybean, flaxseed/linseed, olive) are particularly rich in alpha-linolenic acid. (hmdb.ca)
English walnuts) and vegetable oils (e.g., canola, soybean, flaxseed/linseed, and olive oil) contain alpha-linolenic acid (ALA). (aarpmedicareplans.com)
Dietary sources of Alpha-Linolenic Acid (ALA) include Flaxseed (the highest source), and also to a lesser extent soybeans and soybean oil, canola oil, walnuts, and pumpkin seeds. (invitehealth.com)
The Mediterranean Diet -- which emphasizes whole grains, root and green vegetables, daily servings of fruit, fish and poultry, olive and canola oils, and alpha-linolenic acid (found in flaxseed oil) -- is an example. (adam.com)
Alpha-linolenic oil is available in cooking oils, including canola oil and soybean oil, and in medicinal oils, including flaxseed oil and dietary supplements containing flaxseed oil. (adam.com)
Alpha-linolenic acid can be found in walnut oil, perilla, soy, canola oil and flaxseed oil. (nootriment.com)
Alpha linolenic acid can be purchased as a dietary supplement or consumption can be increased by choosing foods such as perilla seeds, walnuts, pumpkin seeds, canola (rapeseed oil), flaxseeds and soybeans. (nootriment.com)
It is an isomer of α-linolenic acid , which is a polyunsaturated n−3 (omega-3) fatty acid, found in rapeseed canola oil, soybeans , walnuts , flax seed ( linseed oil ), perilla , chia , and hemp seed. (wikipedia.org)
The largest food sources of α-linolenic acid are vegetable oils, such as flax seed oil, soybean oil, and canola oil. (ahajournals.org)

The model predicted plasma values for the n-3 fatty acids in good accordance with the measured steady state concentrations and also predicted dietary linolenic acid intake for each subject in accordance with values determined by lipid analysis of the diet. (nih.gov)
Serum interleukin (IL)-6, IL-1beta, and tumor necrosis factor-alpha (TNF-alpha) concentrations and the production of IL-6, IL-1beta, and TNF-alpha by PBMCs were measured. (nih.gov)
PBMC production of TNF-alpha was inversely correlated with ALA (r = -0.402, P = 0.07) and with eicosapentaenoic acid (r = -0.476, P = 0.03) concentrations in PBMC lipids with the ALA diet. (nih.gov)
9 However, soybean oil is usually partially hydrogenated to produce margarines and vegetable shortenings, with lower α-linolenic acid concentrations and a high content of trans fatty acids, which are positively associated with CHD. (ahajournals.org)
The intake of enriched cheese significantly increased the plasma concentrations of CLA, VA, the n -3 fatty acids ALA and EPA, and more remarkably decreased that of the endocannabinoid anandamide. (cambridge.org)

It is not known if alpha-linolenic acid supplements have these same benefits. (webmd.com)
The rule prohibits certain nutrient content claims for foods, including conventional foods and dietary supplements, that contain omega-3 fatty acids based on our determination that such nutrient content claims do not meet the requirements of the Federal Food, Drug, and Cosmetic Act (FD&C Act). (fda.gov)
Researchers don't know whether taking alpha-linolenic acid supplements would have the same effect as eating foods rich in alpha-linolenic acid. (adam.com)
Researchers don't know whether alpha-linolenic acid supplements would have the same benefits as foods with alpha-linolenic acid. (adam.com)
Several studies suggest that diets or supplements rich in omega-3 fatty acids lower blood pressure slightly in people with hypertension. (adam.com)
To restore a healthy valance, supplements like alpha linolenic acid and fish oil are used. (nootriment.com)
It has yet to be determined whether ALA supplements can provide the same benefits as eating a diet diet high in omega-3 fatty acids, such as the Mediterranean Diet. (nootriment.com)
We only use refrigerated, fresh and unprocessed flax seed oil in our supplements, Our supplements contain the highest level of omega 3 fatty acids when compared to other vegetable oils. (physiciannaturals.com)

Western modern diets are deficient in omega-3 polyunsaturated fatty acids, which are essential for brain health. (archives-ouvertes.fr)
The conversion of alpha-linolenic acid (ALA) to longer chain and more desaturated omega-3 polyunsaturated fatty acids (omega-3 LCPUFA), in particular to DHA, is limited in humans consuming a Westernized diet. (fatsoflife.com)
Alpha-linolenic acid (ALA), the main omega-3 polyunsaturated fatty acid found in terrestrial plants, is an important fatty acid present in the human diet. (fatsoflife.com)
It can be converted in the body to longer chain and more highly unsaturated omega-3 polyunsaturated fatty acids, such as eicosapentaenoic acid (EPA), docosapentaenoic acid ɷ-3 (DPA ɷ-3), and docosahexaenoic acid (DHA). (fatsoflife.com)
These differences could not be explained by the conventional microsomal-peroxisomal pathway of the synthesis of the long-chain omega 6 and omega 3 polyunsaturated fatty acids. (fabresearch.org)

Exposure to dietary intake of alpha- linolenic acid ( ALA ) will be assessed using a detailed food frequency questionaire filled in by participants included in the Diet, Cancer and Health cohort at baseline. (clinicaltrials.gov)
The Alpha Omega Cohort comprises 4,837 patients that suffered a myocardial infarction who are followed up for cause-specific mortality. (alphaomegacohort.org)

α-Linolenic acid can only be obtained by humans through their diets because the absence of the required 12- and 15-desaturase enzymes makes de novo synthesis from stearic acid impossible. (wikipedia.org)
Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. (nih.gov)
We postulate that deficiency of dietary vitamin A and the consequential depletion of retinoids inhibits DHA, and enhances OA, synthesis by differential effects on the independent synthetic pathways of the two fatty acids in the mitochondria. (fabresearch.org)
Synthesis of doxorubicin α-linolenic acid conjugate and evaluation of its antitumor activity. (semanticscholar.org)
C 10 H 18 N 4 O 6 , a compound intermediate in the synthesis of arginine, formed from citrulline and aspartic acid. (thefreedictionary.com)
The time scale of conversion of [ 13 C]ALNA to eicosapentaenoic acid (EPA) and docosapentaenoic acid (DPA) suggested that the liver was the principal site of ALNA desaturation and elongation, although there was some indication of EPA and DPA synthesis by enterocytes. (cambridge.org)
This pattern of 13 C n −3 fatty acid labelling suggests inhibition or restriction of DHA synthesis downstream of DPA. (cambridge.org)

There is some evidence that alpha-linolenic acid from dietary sources might be effective for all these uses except lowering cholesterol . (webmd.com)
Not enough is known yet to be able to rate alpha-linolenic acid's effect on high cholesterol. (webmd.com)
Cholesterol-lowering Medications -- Increasing the amount of omega-3 fatty acids in your diet may help a group of cholesterol-lowering medications known as statins work more effectively. (limamemorial.org)
In addition, walnuts -- which are rich in alpha-linolenic acid -- have been shown to lower cholesterol and triglycerides in people with high cholesterol. (adam.com)
Some studies found that alpha-linolenic acid may help lower cholesterol, while others found it didn't. (adam.com)
RISHON supply Vegetarian Purslane oil Contains pure natural omega-3 fatty acids with no cholesterol at very low calorie. (viprole.com)
Omega-3 fatty acids can increase 'good' HDL cholesterol. (healthline.com)

Nuts, such as walnuts, are good sources of alpha-linolenic acid. (webmd.com)

Brochot A, Guinot M, Auchere D, Macaire JP, Weill P, Grynberg A, Rousseau-Ralliard D: Effects of alpha-linolenic acid vs . docosahexaenoic acid supply on thedistribution of fatty acids among the rat cardiac subcellular membranesafter a short- or long-term dietary exposure. (biomedcentral.com)
Postprandial effects of alpha-linolenic acid (ALA) in women are poorly characterized. (biomedcentral.com)
Because of this, a study to examine the protective effects of alpha-linolenic acid on nephrotoxicity is planned. (cu.edu.tr)

Maintaining a healthy diet rich in sources of alpha linolenic acid may reduce risk factors for heart disease. (nootriment.com)

We recently showed that a combined deficiency of iron (ID) and n-3 fatty acids (n-3 FAD) in rats disrupts brain monoamine metabolism and produces greater memory deficits than ID or n-3 FAD alone. (biomedcentral.com)
Providing these double-deficient rats with either iron (Fe) or preformed docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) alone affected brain monoamine pathways differently from combined repletion and even exacerbated cognitive deficits associated with double-deficiency. (biomedcentral.com)
Today, healthy fatty acid deficiency is epidemic. (greenmedinfo.com)

In industrialized countries, greater part of the consumed trans fatty acids, in USA about 80 percent of the total, are produced industrially, in varying amounts, during partial hydrogenation of edible oils containing unsaturated fatty acids (see below). (tuscany-diet.net)
In these sources trans fatty acids are present in small amounts. (tuscany-diet.net)
During this process trans fatty acids with more than one double bond are formed in small amounts. (tuscany-diet.net)
These inconsistencies could be partially explained by the fact that dietary sources of α-linolenic and trans fatty acids usually overlap, but these nutrients have opposite effects on MI. (ahajournals.org)

There is a complex set of essential fatty acid interactions. (wikipedia.org)
Alpha-linolenic acid is an essential omega-3 fatty acid. (webmd.com)
It is a member of the group of essential fatty acids called omega-3 fatty acids. (hmdb.ca)
alpha-Linolenic acid, in particular, is not synthesized by mammals and therefore is an essential dietary requirement for all mammals. (hmdb.ca)
The main essential fatty acids in the human diet are omega-3 and omega-6 fatty acids. (goodearthnaturalfoods.com)
Omega-9 fatty acids, which are not considered essential, can be found in animal fat and olive oil. (goodearthnaturalfoods.com)
This is why they are termed essential fatty acids. (healthline.com)
With low levels of taurine, essential fatty acids are not absorbed sufficiently. (schizepigenetics.com)
Flax Seed Oil supplied by RISHON is a wonderful vegetarian source of Alpha Linolenic Acid (ALA) as an essential fatty acids. (viprole.com)
Perilla seed oil is a great source of omega-3 essential fatty acids. (viprole.com)
Natural News ) Omega-3 fatty acids are essential nutrients that have varying roles in different bodily functions and offer several health benefits. (naturalnews.com)
L inseed Oil contains omega-6 and omega-9 essential fatty acids, B vitamins, potassium, lecithin, magnesium, fiber, protein, and zinc and also provides approximately 50% more omega-3 oils than what you could get from taking fish oil. (physiciannaturals.com)
Light and oxygen will slowly breakdown the essential fatty acids. (physiciannaturals.com)
Seabuckthorn Berry Seed Oil can be abundant in Linolenic Acid, an omega-3 essential fatty acid. (aromaweb.com)
Those fatty acids that we cannot manufacture and need to acquire from our diet are called Essential Fatty Acids (EFAs). (aromaweb.com)
Essential Fatty Acids are necessary for human functions and healthy, youthful skin. (aromaweb.com)
Those that are lacking in the proper intake of Essential Fatty Acids may demonstrate seriously dry skin or they may be prone to more serious skin conditions including psoriasis and eczema. (aromaweb.com)
Using carrier oils that are rich in essential fatty acids and including a diet rich in Essential Fatty Acids can significantly help nourish and improve the look and feel of the skin. (aromaweb.com)
Alpha-Linolenic Acid (C18:3) is an polyunsaturated omega-3 essential fatty acid. (aromaweb.com)
These two fatty acids must be supplied by the diet and are therefore considered essential fatty acids (EFAs). (prohealth.com)
Alpha-linolenic acid is an essential (need/can't make) polyunsaturated omega-3 fatty acid that must be obtained in the diet. (glutenfreeworks.com)
EPA (eicosapentaenoic acid) is an essential omega-3 fatty acid that is crucial for fetal brain and retina development and the child's subsequent neurodevelopment among very many other activities in people of all ages. (glutenfreeworks.com)
Docosahexaenoic acid (DHA) is an essential omega-3 fatty acid that is abundant in the brain, being crucial in brain structure. (glutenfreeworks.com)
Nutritionally, the seeds of the plant are one of the most complete sources of vitamins, minerals, essential fatty acids, and potent antioxidant activity. (globalhealingcenter.com)
Omega-6 fatty acids are also essential, so you need to obtain them from your diet. (healthline.com)
Essential fatty acids, or EFAs, are fatty acids that humans and other animals must ingest because the body requires them for good health but cannot synthesize them. (wikipedia.org)
Essential fatty acids should not be confused with essential oils, which are "essential" in the sense of being a concentrated essence. (wikipedia.org)
The biological effects of the ω-3 and ω-6 fatty acids are mediated by their mutual interactions, see Essential fatty acid interactions for detail. (wikipedia.org)
In the body, essential fatty acids serve multiple functions. (wikipedia.org)
ω-9 fatty acids are not essential in humans because they can be synthesized from carbohydrates or other fatty acids. (wikipedia.org)

Influence of dietary fatty acids on cytokine production and its clinical implications. (semanticscholar.org)

Some nuts, seeds, and vegetable oils contain alpha-linolenic acid (ALA), which may be converted to DHA and EPA in the body. (goodearthnaturalfoods.com)
These contain alpha-linolenic acid (LNA). (nutritionvista.com)

Omega-3 fatty acids like alpha-linolenic acid are important structural components of cell membranes. (hmdb.ca)
C 20 H 32 O 2 , an omega-6 fatty acid formed by the action of enzymes on phospholipids in cell membranes. (thefreedictionary.com)
According to another source, author Susan Allport, reducing our omega-6:omega-3 ratio in our diets to 4:1 "produces a 1:1 ratio of HUFAs [highly unsaturated fatty acids] in cell membranes. (sourcewatch.org)

The vitamin A metabolite, 9-cis retinoic acid, is the most potent ligand of RXR. (fabresearch.org)

For instance, ω-3 18:4, or 18:4 ω-3, or 18:4 n−3 indicates stearidonic acid, an 18-carbon chain with 4 double bonds, and with a double bond between the third and fourth carbon atoms from the CH3 end. (wikipedia.org)

ALA and oleic acid levels were significantly increased in plasma after ALA-rich oil and olive oil meals, respectively. (biomedcentral.com)

From GLA, the body forms dihomo-γ-linolenic acid (DGLA). (wikipedia.org)

Also, our findings suggest that a diet-induced enhancement of the cell membrane content of highly unsaturated fatty acids is only possible up to a certain level. (biomedcentral.com)
Within the human body, omega-3s and omega-6 fatty acids essentially "compete" with one another for a limited amount of enzymes available to desaturate and elongate them into the long chain highly unsaturated fatty acids the body needs. (sourcewatch.org)

We therefore studied the postprandial lipid response of women to an ALA-rich oil in comparison with olive oil and butter, and characterized the fatty acid composition of total lipids, TAGs, and non-esterified fatty acids (NEFAs) in plasma. (biomedcentral.com)
The ALA-rich oil significantly affected different plasma lipid fractions and improved the ratio of n-6 to n-3 fatty acids several hours postprandially. (biomedcentral.com)
Lipid extracts were fractionated into neutral lipids, free fatty acids, and polar lipids, prior to derivatization and GC-MS analysis. (hindawi.com)
The highest amounts of n -3 fatty acids are found within the neutral lipid fractions with 590.6 ug/g dry weight and 100.9 ug/g dry weight for blade and stipe, respectively. (hindawi.com)

A linolenic acid with cis -double bonds at positions 9, 12 and 15. (ebi.ac.uk)
It is a carboxylic acid with an 18-carbon chain and three cis double bonds. (wikipedia.org)
The hydrogenation of unsaturated fatty acids involves the addition of hydrogen atoms to double bonds on the carbon chains of fatty acids . (tuscany-diet.net)
Lineolic acid is a polyunsaturated omega-6 18 carbon long fatty acid, with two CC double bonds at the 9- and 12-positions. (foodb.ca)
Omega-3 fatty acids are polyunsaturated, meaning they have two or more double bonds (poly = many) in their chemical structure. (healthline.com)
Together they mean that omega-3 fatty acids have many double bonds. (healthline.com)
Typically, the number of carbons and the number of double bonds are also listed in short descriptions of unsaturated fatty acids. (wikipedia.org)
However, humans can convert both LA and ALA to fatty acids with longer carbon chains and a larger number of double bonds, by alternative desaturation and chain elongation. (wikipedia.org)

Palmitic acid was significantly increased in plasma-TAG after the butter meal. (biomedcentral.com)
Rishon supply sea buckthorn seed Oil,CAS:225234-03-7, Sea buckthorn seed oil is rich in omega3,6,9 fatty acids as alpha linolenic acid,linolecic acid,Palmitic Acid,Stearic Acid. (viprole.com)

Multiple studies have shown a relationship between α-linolenic acid and an increased risk of prostate cancer. (wikipedia.org)
Ironically, alpha-linolenic acid may actually raise some men's risk of getting prostate cancer . (webmd.com)
There is contradictory evidence about the role of alpha-linolenic acid in prostate cancer. (webmd.com)
Some research suggests that high dietary intake of alpha-linolenic acid might increase the risk of getting prostate cancer. (webmd.com)
Alpha-linolenic acid from dairy and meat sources has been positively associated with prostate cancer. (webmd.com)
Alpha-linolenic acid from plant sources, such as flaxseed, does not affect prostate cancer risk. (webmd.com)
Dietary fat, fatty acids, and risk of prostate cancer in the NIH-AARP diet and health study. (semanticscholar.org)
Dietary fatty acid intake and prostate cancer survival in Örebro County, Sweden. (semanticscholar.org)
Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer. (semanticscholar.org)
Fatty acids and risk of prostate cancer in a nested case-control study in male smokers. (semanticscholar.org)
The association of fatty acids with prostate cancer risk. (semanticscholar.org)
Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. (semanticscholar.org)
We tested the hypothesis that alpha linolenic acid (ALA) increases the serum concentration of prostate-specific antigen (PSA), a biomarker of prostate cancer. (alphaomegacohort.org)

Table 1 Formulation and fatty acid composition of the experimental diets. (biomedcentral.com)

The diets varied in the percentage of energy (en%) of LA (0.07-17.1 en%) and ALA (0.02-12.1 en%) by manipulating both the fat content and the balance of vegetable oils. (nih.gov)
The reaction occurs in presence of metal catalyst and hydrogen, and is favored by heating vegetable oils containing unsaturated fatty acids . (tuscany-diet.net)
Omega-6 fatty acids are well-supplied in the diet by meat and vegetable oils. (prohealth.com)

Oxidative instability of α-linolenic acid is one reason why producers choose to partially hydrogenate oils containing α-linolenic acid, such as soybean oil. (wikipedia.org)
Nonhydrogenated soybean oil contains ≈7% to 10% α-linolenic acid. (ahajournals.org)

The amounts of polyunsaturated fatty acids are 3.4 times higher in blade than stipe. (hindawi.com)

α-Linolenic acid is relatively more susceptible to oxidation and will become rancid more quickly than many other oils. (wikipedia.org)
Foods that provide omega-3 fatty acids include fish oil and certain plant and nut oils, while omega-6 fatty acids can be found in palm, soybean, rapeseed, and sunflower oils. (goodearthnaturalfoods.com)
Dietary sources of omega-3 fatty acids include fish oil and certain plant/nut oils. (aarpmedicareplans.com)
For a categorized list of fatty acids, see Fatty Acids Typically Found in Carrier Oils . (aromaweb.com)

The first double bond is located at the third carbon from the methyl end of the fatty acid chain, known as the n end. (wikipedia.org)
Plant chloroplasts consisting of more than 95 percent of photosynthetic thylakoid membranes are highly fluid due to the large abundance of linolenic acid, that shows up as sharp resonances in high-resolution carbon-13 NMR spectra, invariably. (wikipedia.org)
In all omega-3 fatty acids, the first double bond is located between the third and fourth carbon atom counting from the methyl end of the fatty acid (n-3). (hmdb.ca)
Although humans and other mammals can synthesize saturated and some monounsaturated fatty acids from carbon groups in carbohydrates and proteins, they lack the enzymes necessary to insert a cis double bond at the n-6 or the n-3 position of a fatty acid. (hmdb.ca)
During partial hydrogenation, an incomplete saturation of the unsaturated sites on the carbon chains of unsaturated fatty acids occurs. (tuscany-diet.net)
Like all fatty acids, omega-3s are chains of carbon, hydrogen and oxygen atoms. (healthline.com)
The omega system of fatty acid classification pertains to the carbon atom structure of unsaturated fatty acids. (aromaweb.com)
This 18-carbon fatty acid can be converted into EPA and DHA, although the process is not very efficient. (healthline.com)

High DIETARY intake of alpha-linolenic acid over a period of 6 years seems to reduce the risk of a first heart attack by as much as 59% in both men and women. (webmd.com)
High dietary intake of alpha-linolenic acid seems to reduce the "plaque" in arteries serving the heart. (webmd.com)
We prospectively examined the association between dietary intake of alpha-linolenic acid assessed via updated food-frequency questionnaires and the risk of SCD, other fatal CHD, and nonfatal myocardial infarction (MI) among 76,763 women participating in the Nurses' Health Study who were free from cancer and completed a dietary questionnaire at baseline in 1984. (unboundmedicine.com)
After controlling for coronary risk factors and other fatty acids, including long-chain n-3 fatty acids, the intake of alpha-linolenic acid was inversely associated with the risk of SCD (P for trend, 0.02) but not with the risk of other fatal CHD or nonfatal MI. (unboundmedicine.com)
These prospective data suggest that increasing dietary intake of alpha-linolenic acid may reduce the risk of SCD but not other types of fatal CHD or nonfatal MI in women. (unboundmedicine.com)

Eating a diet high in alpha-linolenic acid seems to reduce risk of hypertension by about a third. (webmd.com)
ALA is a fatty acid that cannot be made by the body and must be supplied in the diet. (news-medical.net)
Subjects received a 1-g oral dose of an isotope tracer of alpha-linolenate (d5-18:3n-3 ethyl ester) while subsisting on a rigorously controlled beef-based diet. (nih.gov)
According to UMMC, people who eat a diet rich in alpha-linolenic acid are less likely to suffer from a fatal heart attack. (livestrong.com)
The present study investigates the benefits of the dietary intake of chia seed (Salvia hispanica L.) rich in alpha-linolenic acid and fibre upon dyslipidaemia and insulin resistance (IR), induced by intake of a sucrose-rich (62.5 %) diet (SRD). (greenmedinfo.com)
Alpha-linolenic acid (ALA) is the most common omega-3 fatty acid in the Western diet. (springer.com)
A healthy diet should consist of roughly 2 - 4 times more omega-6 fatty acids than omega-3 fatty acids. (nutritionvista.com)
In spite of increases of serum n-3 fatty acids, the OxLDL concentration did not change significantly when given the PO diet. (fao.org)
Within the common Western diet, ALA represents the quantitatively dominant fatty acid of the n3 series. (biomedcentral.com)
One study suggests that people who eat a diet high in alpha-linolenic acid are less likely to have a fatal heart attack. (adam.com)
Infants who are breastfed should get enough alpha-linolenic acid if the mother eats a healthy diet. (adam.com)
Correlations between α-linolenic acid-improved multitissue homeostasis and gut microbiota in mice fed a high-fat diet. (greenmedinfo.com)
The simplest is called alpha-linolenic acid, or ALA. Like most vitamins, ALA is especially important in our diet because our bodies cannot make it from scratch. (whfoods.com)
Just like the omega-6s, omega-3 fatty acids cannot be made by the body and we must get them from the diet. (healthline.com)
The Western diet tends to contain an over-abundance of omega-6 and not enough omega-3 fatty acids. (nootriment.com)
In a prospective, randomised single-blinded secondary prevention trial we compared the effect of a Mediterranean alpha-linolenic acid-rich diet to the usual post-infarct prudent diet. (paleoforlife.org)
An alpha-linolenic acid-rich Mediterranean diet seems to be more efficient than presently used diets in the secondary prevention of coronary events and death. (paleoforlife.org)
1,8 However, these foods generally do not contribute much α-linolenic acid to the diet. (ahajournals.org)
The ratio of 2.3:1 translates to 6.7g n-6 fatty acids and 2.9g n-3 fatty acids in a 8360 kJ (2000 kcal) diet. (sourcewatch.org)
The difficulty in meeting the recommended ratio is that many foods typically consumed in the American diet simply have a ratio of n-6 to n-3 fatty acids far above 2.3:1. (sourcewatch.org)
However, it's important to get the right balance of omega-3, -6 and -9 fatty acids in your diet. (healthline.com)
ratio of omega-6 to omega-3 fatty acids in the diet is 4:1 or less. (healthline.com)
Background: Alpha-linolenic acid (ALA) is the most common omega-3 fatty acid in the Western diet. (wustl.edu)

Eicosapentaenoic and docosapentaenoic acids are the. (cambridge.org)

We examined the association between adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction (MI) in a population-based case-control study in Costa Rica. (unboundmedicine.com)
TY - JOUR T1 - Adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction in Costa Rica. (unboundmedicine.com)

Due to these potential health benefits, fish oil, which is rich in omega-3 fatty acids, has become a popular supplement. (goodearthnaturalfoods.com)
Diets rich in omega-3 fatty acids have been shown to lower blood pressure slightly in individuals with hypertension. (nootriment.com)

Organisms2

Chemicals and Drugs24

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High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice. (1/510)

Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men. (2/510)

Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. (3/510)

Prevention of sudden cardiac death by dietary pure omega-3 polyunsaturated fatty acids in dogs. (4/510)

Antisense-mediated depletion of potato leaf omega3 fatty acid desaturase lowers linolenic acid content and reduces gene activation in response to wounding. (5/510)

Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. (6/510)

Salicylhydroxamic acid inhibits delta6 desaturation in the microalga Porphyridium cruentum. (7/510)

Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures. (8/510)

alpha-Linolenic Acid

Linolenic Acids

Linoleic Acids

Linoleic Acid

Fatty Acids, Unsaturated

Fatty Acids, Essential

Fatty Acids

gamma-Linolenic Acid

Dietary Fats, Unsaturated

Plant Oils

Stearic Acids

Lipoxygenase

Linseed Oil

Docosahexaenoic Acids

Fatty Acid Desaturases

Chromatography, Gas

Phospholipids

Flax

Borago

Dietary Fats

Dictionaries, Chemical

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Lipoxins

Arachidonic Acid

Cyclooxygenase Inhibitors

Aristolochic Acids

Fatty Acids, Omega-3

High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice. (1/510)

Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men. (2/510)

Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. (3/510)

Prevention of sudden cardiac death by dietary pure omega-3 polyunsaturated fatty acids in dogs. (4/510)

Antisense-mediated depletion of potato leaf omega3 fatty acid desaturase lowers linolenic acid content and reduces gene activation in response to wounding. (5/510)

Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. (6/510)

Salicylhydroxamic acid inhibits delta6 desaturation in the microalga Porphyridium cruentum. (7/510)

Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures. (8/510)

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