A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.
Cyclic GLUCANS consisting of six (6) glucopyranose units linked by 1,4-glycosidic bonds.
Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.
Cyclic GLUCANS consisting of eight (8) glucopyranose units linked by 1,4-glycosidic bonds.
A phenothiazine derivative that is used as an antipruritic.
Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS.
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. It is the chief storage form of energy reserve (carbohydrates) in plants.
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
A family of gram-positive, saprophytic bacteria occurring in soil and aquatic environments.
The rotation of linearly polarized light as it passes through various media.
A measure of relative protection provided by SUNSCREENING AGENTS against burns due to ultraviolet (UV) radiation from a light source.
Enzymes that catalyze the endohydrolysis of 1,4-alpha-glycosidic linkages in STARCH; GLYCOGEN; and related POLYSACCHARIDES and OLIGOSACCHARIDES containing 3 or more 1,4-alpha-linked D-glucose units.
Salts and esters of the 14-carbon saturated monocarboxylic acid--myristic acid.
An enzyme that catalyzes the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of polysaccharide chains with the release of beta-glucose. It is also able to hydrolyze 1,6-alpha-glucosidic bonds when the next bond in sequence is 1,4.
The chemical and physical integrity of a pharmaceutical product.
Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor molecule which is frequently another carbohydrate. EC 2.4.1.-.
An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.
The thermodynamic interaction between a substance and WATER.
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.
Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
The rate dynamics in chemical or physical systems.
A genus of BACILLACEAE that are spore-forming, rod-shaped cells. Most species are saprophytic soil forms with only a few species being pathogenic.
Shortened forms of written words or phrases used for brevity.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
An enzyme that catalyzes the hydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides so as to remove successive beta-maltose units from the non-reducing ends of the chains. EC 3.2.1.2.
A subclass of alpha-amylase ISOENZYMES that are secreted into PANCREATIC JUICE.
The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A genus of gram-positive bacteria in the family Thermoactinomycetaceae, that can cause FARMER'S LUNG.
A form of alveolitis or pneumonitis due to an acquired hypersensitivity to inhaled antigens associated with farm environment. Antigens in the farm dust are commonly from bacteria actinomycetes (SACCHAROPOLYSPORA and THERMOACTINOMYCES), fungi, and animal proteins in the soil, straw, crops, pelts, serum, and excreta.
An order of gram-positive, primarily aerobic BACTERIA that tend to form branching filaments.
Exclusive legal rights or privileges applied to inventions, plants, etc.
Submicron-sized fibers with diameters typically between 50 and 500 nanometers. The very small dimension of these fibers can generate a high surface area to volume ratio, which makes them potential candidates for various biomedical and other applications.
A group of amides with the general formula of R-CONH2.
The conformation, properties, reaction processes, and the properties of the reactions of carbon compounds.
The normal length of time of an organism's life.
Decrease in existing BODY WEIGHT.
An enzyme that catalyzes the formation of thiamine pyrophosphate from ATP and thiamine. EC 2.7.6.2.
A status with BODY WEIGHT that is above certain standard of acceptable or desirable weight. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal "over fat".
Reduction in caloric intake without reduction in adequate nutrition. In experimental animals, caloric restriction has been shown to extend lifespan and enhance other physiological variables.
Based on known statistical data, the number of years which any person of a given age may reasonably expected to live.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.

Properties of a cyclodextrin-specific, unusual porin from Klebsiella oxytoca. (1/76)

The function of CymA, 1 of the 10 gene products involved in cyclodextrin uptake and metabolism by Klebsiella oxytoca, was characterized. CymA is essential for growth on cyclodextrins, but it can also complement the deficiency of a lamB (maltoporin) mutant of Escherichia coli for growth on linear maltodextrins, indicating that both cyclic and linear oligosaccharides are accepted as substrates. CymA was overproduced in E. coli and purified to apparent homogeneity. CymA is a component of the outer membrane, is processed from a signal peptide-containing precursor, and possesses a high content of antiparallel beta-sheet. Incorporation of CymA into lipid bilayers and conductance measurements revealed that it forms ion-permeable channels, which exhibit a substantial current noise. CymA-induced membrane conductance decreased considerably upon addition of alpha-cyclodextrin. Titration experiments allowed the calculation of a half-saturation constant, K(S), of 28 microM for its binding to CymA. CymA assembled in vitro to two-dimensionally crystalline tubular membranes, which, on electron microscopy, are characterized by a p1-related two-sided plane group. The crystallographic unit cell contains four monomeric CymA molecules showing a central pore. The lattice parameters are a = 16.1 nm, b = 3.8 nm, gamma = 93 degrees. CymA does not form trimeric complexes in lipid membranes and shows no tendency to trimerize in solution. CymA thus is an atypical porin with novel properties specialized to transfer cyclodextrins across the outer membrane.  (+info)

Enzymatic synthesis of N-acetylglucosaminyl-cyclodextrin by the reverse reaction of N-acetylhexosaminidase from jack bean. (2/76)

Novel heterobranched cyclodextrins (CDs), N-acetylglucosaminyl-cyclodextrins (GlcNAc-CD), were synthesized from a mixture of GlcNAc and alpha, beta, or gamma CD by the reverse reaction of N-acetylhexosaminidase from jack bean. Optimum pH and temperature for the production of GlcNAc-alpha CD by N-acetylhexosaminidase were pH 4.9 and 50-70 degrees C, respectively. The maximum yield of GlcNAc-alpha CD was 17.5% (mol/mol) at the concentration of 1 M GlcNAc and 0.25 M alpha CD. The reverse reaction product, GlcNAc-alpha CD, was separated into two peaks by HPLC analysis on the ODS column. Their structures were identified as 6-O-beta-D-N-acetylglucosaminyl-alpha CD and 2-O-beta-D-N-acetylglucosaminyl-alpha CD by FAB-MS and NMR spectroscopies. N-Acetylhexosaminidase from jack bean also synthesized N-acetylgalactosaminyl-alpha CD from N-acetylgalactosamine and alpha CD.  (+info)

Probing protein-sugar interactions. (3/76)

We have investigated the partial specific volumes (2) (ml/g), hydration, and cosolvent interactions of rabbit muscle aldolase by equilibrium sedimentation in the analytical ultracentrifuge and by direct density increment (partial differential/partial differentialc(2))(mu) measurements over a range of sugar concentrations and temperature. In a series of sugars increasing in size, glucose, sucrose, raffinose, and alpha-cyclodextrin, (partial differential/ partial differentialc(2))(mu) decreases linearly with the solvent density rho(0). These sugar cosolvents do not interact with the protein; however, the interaction parameter B(1) (g water/g protein) mildly increases with increasing sugar size. The experimental B(1) values are smaller than values calculated by excluded volume (rolling ball) considerations. B(1) relates to hydration in this and in other instances studied. It decreases with increasing temperature, leading to an increase in (2) due to reduced water of hydration electrostriction. The density increments (partial differential/ partial differentialc(2))(mu), however, decrease in concave up form in the case of glycerol and in concave down form for trehalose, leading to more complex behavior in the case of carbohydrates playing a biological role as osmolytes and antifreeze agents. A critical discussion, based on the thermodynamics of multicomponent solutions, is presented.  (+info)

alpha-cyclodextrin extracts diacylglycerol from insect high density lipoproteins. (4/76)

alpha-Cyclodextrins are water-soluble cyclic hexamers of glucose units with hydrophobic cavities capable of solubilizing lipophiles. Incubating alpha-cyclodextrin with high density lipophorin from Manduca sexta or Bombyx mori resulted in a cloudy, turbid solution. Centrifugation separated a pale yellowish precipitate. Thin-layer chromatography analysis of the lipid extract of the precipitate showed that the major lipid was diacylglycerol, while KBr density gradient analysis of the supernatant demonstrated the presence of a lipid-depleted very high density lipophorin. Transfer of diacylglycerol from lipophorin to cyclodextrin was specific to alpha-cyclodextrin and was not observed with beta- or gamma-cyclodextrins. pH had no effect on diacylglycerol transfer to alpha-cyclodextrin. However, the transfer was strongly dependent on the concentration of alpha-cyclodextrin and temperature. Increasing the concentration of alpha-cyclodextrin in the incubation mixture was associated with the formation of increasingly higher density lipophorins. Thus, at 20, 30, and 40 mm alpha-cyclodextrin, the density of B. mori lipophorin increased from 1.107 g/ml to 1.123, 1. 148, and 1.181 g/ml, respectively. At concentrations greater than 40 mm, alpha-cyclodextrin had no further effect on the density of lipophorin. alpha-Cyclodextrin removed at most 83;-87% of the diacylglycerol present in lipophorin. Temperature played an important role in altering the amount of diacylglycerols transferred to alpha-cyclodextrin. At 30 mm alpha-cyclodextrin, the amount of diacylglycerol transferred at different temperatures was 50% at 4 degrees C, 41% at 15 degrees C, 20% at 28 degrees C, and less than 3% at 37 degrees C. We propose that diacylglycerol transfers to alpha-cyclodextrin via an aqueous diffusion pathway and that the driving force for the transfer is the formation of an insoluble alpha-cyclodextrin-diacylglycerol complex.  (+info)

Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying. (5/76)

The taste and flavor of spray-dried powdered products are the most important quality factors. In the present study, molecular encapsulation in cyclodextrin was applied to prevent the loss of a hydrophobic flavor compound (l-menthol) during the drying of a droplet. beta-Cyclodextrin appeared to be a better encapsulant for menthol than alpha- and gamma-cyclodextrin. The retention of menthol increased with increasing concentration of both cyclodextrin and maltodextrin. A simple mathematical model is proposed for estimating the flavor retention. The theoretical results by this model estimated well the final retention of menthol encapsulated in a blend of beta-cyclodextrin and maltodextrin.  (+info)

Mechanism of porcine pancreatic alpha-amylase. Inhibition of amylose and maltopentaose hydrolysis by alpha-, beta- and gamma-cyclodextrins. (6/76)

The effects of alpha-, beta- and gamma-cyclodextrins on the amylose and maltopentaose hydrolysis catalysed by porcine pancreatic alpha-amylase (PPA) were investigated. The results of the statistical analysis performed on the kinetic data using the general initial velocity equation of a one-substrate reaction in the presence of one inhibitor indicate that the type of inhibition involved depends on the substrate used: the inhibition of amylose hydrolysis by alpha-, beta- and gamma-cyclodextrin is of the competitive type, while the inhibition of maltopentaose hydrolysis is of the mixed noncompetitive type. Consistently, the Lineweaver-Burk plots intersect on the vertical axis when amylose is used as the substrate, while in the case of maltopentaose, the intersection occurs at a point located in the second quadrant. The inhibition of the hydrolysis therefore involves only one abortive complex, PPA-cyclodextrin, when amylose is used as the substrate, while two abortive complexes, PPA-cyclodextrin and PPA-maltopentaose-cyclodextrin, are involved with maltopentaose. The mixed noncompetitive inhibition thus shows the existence of one accessory binding site. In any case, only one molecule of inhibitor binds to PPA. In line with these findings, the difference spectra of PPA produced by alpha-, beta- and gamma-cyclodextrin indicate that binding occurs at a tryptophan and a tyrosine residue. The corresponding dissociation constants and the inhibition constants obtained using the kinetic approach are in the same range (1.2-7 mM). The results obtained here on the inhibition of maltopentaose hydrolysis by cyclodextrin are similar to those previously obtained with acarbose as the inhibitor [Alkazaz, M., Desseaux, V., Marchis-Mouren, G., Prodanov, E. & Santimone, M. (1998) Eur. J. Biochem. 252, 100-107], but differ from those obtained with amylose as the substrate and acarbose as inhibitor [Alkazaz, M., Desseaux, V., Marchis-Mouren, G., Payan, F., Forest, E. & Santimone, M. (1996) Eur. J. Biochem. 241, 787-796]. It is concluded that the hydrolysis of both long and short chain substrates requires at least one secondary binding site, including a tryptophan residue.  (+info)

Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media. (7/76)

Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with a- and /-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-beta-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 x 10(5) mol(-2) l(2) was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.  (+info)

Pharmacokinetics and pharmacodynamics of human chorionic gonadotropin (hCG) after rectal administration of hollow-type suppositories containing hCG. (8/76)

To determine the effectiveness of human chorionic gonadotropin (hCG) administered rectally, we studied the pharmacokinetics and pharmacodynamics of hCG using a hollow-type suppository. HCG was not detected in plasma when only hCG was administered rectally, even at a higher dose (4,000 IU/kg body weight) than intravenous injection, because of its low bioavailability due to high molecular weight or degradation by proteolytic activity. To enhance the rectal absorption of hCG, the effectiveness of its coadministration with alpha-cyclodextrin (alpha-CyD), an absorption-enhancing agent, was investigated in male rabbits. HCG was detected in plasma following coadministration of hCG and alpha-CyD (10 mg/kg body weight) into the rectum. The plasma hCG concentration increased with increasing dose of alpha-CyD. The AUC(0-48) observed after coadministration of hCG and alpha-CyD at 30 mg/kg body weight was approximately four times higher than that of hCG and alpha-CyD at 10mg/kg body weight. HCG at a high concentration induced a rapid increase in the plasma testosterone concentration (74.2 +/- 3.4 ng/ml) 2 h after intravenous administration. However, the testosterone concentration 24 h after intravenous administration decreased to the physiological level (approximately 20 ng/ml) which had been observed before such administration. On the other hand, the maximum level of testosterone concentration (40.0 +/- 12.6 ng/ml) was observed 24 h after rectal administration of hCG (400 IU/kg body weight) in combination with alpha-CyD (30 mg/kg body weight). Moreover, the plasma testosterone concentration (31.0 +/- 11.4 ng/ml) obtained 72 h after rectal administration tended to be maintained at a higher level than that (14.4 +/- 0.9ng/ml) observed before the administration. These results suggest that the hollow-type suppository as a rectal delivery system of hCG is promising as a new mode of hCG therapy.  (+info)

alpha-Cyclodextrin (α-dextrin, α-cyclodextrin, α-CD, alphadextrin, alpha cyclodextrin (dietary fiber)) is a polysaccharide of six glucose units that are covalently attached end to end via α-1, 4 linkages. This fiber is sold under the brand names, Alpha-Fibe and Calorease. Alpha-Fibe is the original product that contains this unique fiber, introduced to the worldwide nutritional supplement market by Bio-Form Essentials in 2007. Soho Flordis International became the patent Assignee as of March 30, 2012 and launched the brand Calorease in 2013. FBCx is not an ingredient, only an abbreviation, and is not part of the scientific name. The abbreviation FBCx, stands for Fat Binding Complexer and can be associated with the brand names, Alpha-Fibe and Calorease. There are two other naturally occurring cyclodextrins, β (beta) - and γ (gamma) -, which contain seven and eight glucose units respectively. In water, these fibers take on a toroid or truncated cone configuration. In aqueous ...
Patients with advanced cirrhosis often develop a hyperdynamic circulation with central hypovolaemia. The events that initiate the systemic haemodynamic abnormalities and the coupling of these factors to splanchnic haemodynamics are still unclear. Objective On the basis of a large population of patients with cirrhosis to identify splanchnic and clinical characteristics associated with the development of the hyperdynamic circulation and survival ...
3L2M: X-ray crystallographic analyses of pig pancreatic alpha-amylase with limit dextrin, oligosaccharide, and alpha-cyclodextrin.
Incorporates a phase consisting of a 2,6-di-O-pentyl-3-trifluoroacetyl derivative of alpha-cyclodextrin. Exhibits high selectivity for oxygen containing analytes in the form of alcohols, ketones, acids, aldehydes, and lactones. Highly selective for halogenated compounds.
A chain superstructure is formed (bundles of needles) is formed during rapid co-precipitation of alpha-cyclodextrin (cyclic starch w/ glucose) and KAuBr4 in ...
SFX-01 is a synthetic version of the naturally occurring compound sulforaphane, which has been stabilised in an alpha-cyclodextrin lattice. Evgen Pharma is currently conducting two Phase II trials of SFX-01, one in advanced breast cancer and one in a type of stroke called subarachnoid haemorrhage.. The patent granted today, which covers the manufacturing and scale-up of SFX-01, marks the first patent to be granted for SFX-01 in Europe, where a composition of matter patent is also pending. Todays patent grant marks the Companys eighth patent to be granted this year, reflecting the growth in the Companys patent estate.. The European patent, numbered EP2854861 and entitled Method of Synthesising Sulforaphane, can be viewed at this link: https://register.epo.org/application?number=EP13726846&tab=doclist. The patent runs until May 2033.. This core manufacturing patent has already been granted in the United States, Australia and Japan and is pending in other countries worldwide.. Evgen Pharma holds ...
COMMUNICATIONS (C;imhridge Skieoscm 250 M3). The density of the synthesized material ({I = 2.47 gcni I ) was determined with the suspension method using butyl acetate and broinoforni as suspension liquids N M R experiments were carried out on a Bruker ASX 400 spectrometer at 79.495 MHz for Si. Received: July 2. 1994 [Z7092IE] German version: Arrgm.. C,iwi. 1995. 107. 12.5 - Keywords: silicon compounds structure elucidation zeolites zinc compounds bonds results in the specific and enthalpicallq strong binding of the anionic guest ion.[5.61 In order to mimic this natural binding principle we designed the artificial hosts 1 and 2. By virtue of the electrostatic repulsion of the inner cationic centers these molecules are inclined to adopt inflated conformations with cavities which may encapsu- - 111 J. V Smith. ~ / 7 ~ 1 ? 7Reij. . 1988. 8. 149. (21 (3 0. Brunner. W. M. Meier. Nurure 1989. 337, 146. [3] S . Merlino. tur. J Minrrul. 1990. 2,809. [4] M. J. Anncn. M . E. Davis. J. B. Higgins. J. L. ...
In biochemistry, intercalation is the insertion of molecules between the bases of DNA. This process is used as a method for analyzing DNA and it is also the basis of certain kinds of poisoning. Clathrates are chemical substances consisting of a lattice that traps or contains molecules. Usually, clathrate compounds are polymeric and completely envelop the guest molecule. Inclusion compounds are often molecules, whereas clathrates are typically polymeric. Intercalation compounds are not 3-dimensional, unlike clathrate compounds.[6] According to IUPAC, clathrates are Inclusion compounds in which the guest molecule is in a cage formed by the host molecule or by a lattice of host molecules.[7] ...
The absolute configuration and structure of aegelinol, a pyranocoumarin isolated from Ferulago asparagifolia Boiss (Apiaceae), has been determined by crystallography. Crystal structure of the inclusion complex of aegelinol in β-cyclodextrin was determined (a = 15.404(1) Å, b = 15.281(1) Å, c = 17.890(1) Å, α = 99.662(1), β = 113.4230(1), γ = 102.481(1)°, P1; R1 = 6.71%) and allowed unambiguous determination of the absolute configuration of the stereogenic center of aegelinol. The pyranocoumarin guest is included within the cylindrical cavity formed by dimeric β-cyclodextrin molecules with a head-to-head arrangement. Crystal structure of aegelinol alone was also determined (a = 6.8921(3) Å, b = 11.4302(9) Å, c = 44.964(3) Å, P212121; R1 = 4.44%) and allowed precise determination of its geometry. Aegelinol crystallizes with three molecules in the asymmetric unit held together by H-bonds and π-stacking interactions.
The absolute configuration and structure of aegelinol, a pyranocoumarin isolated from Ferulago asparagifolia Boiss (Apiaceae), has been determined by crystallography. Crystal structure of the inclusion complex of aegelinol in β-cyclodextrin was determined (a = 15.404(1) Å, b = 15.281(1) Å, c = 17.890(1) Å, α = 99.662(1), β = 113.4230(1), γ = 102.481(1)°, P1; R1 = 6.71%) and allowed unambiguous determination of the absolute configuration of the stereogenic center of aegelinol. The pyranocoumarin guest is included within the cylindrical cavity formed by dimeric β-cyclodextrin molecules with a head-to-head arrangement. Crystal structure of aegelinol alone was also determined (a = 6.8921(3) Å, b = 11.4302(9) Å, c = 44.964(3) Å, P212121; R1 = 4.44%) and allowed precise determination of its geometry. Aegelinol crystallizes with three molecules in the asymmetric unit held together by H-bonds and π-stacking interactions.
We synthesized the new supramolecular host molecules 7 and 13 based on functionalized resorcarenes bearing Kemps triacid. Conformations in solution have been investigated and the influence of intra-and intermolecular hydrogen bonds from the triacid was shown by low temperature and DOSY NMR experiments. The results of host 7 are supported by DFT calculations. The binding behaviour of 7 towards different 2-amino pyridincs in chloroform has been investigated by NMR titrations. The association constants reach from K 207 M-1 for 2-amino-5-cyano pyridine to K=1551 M-1 for 2-amino-4-methyl pyridine. The association constants of the formed complexes of 7 with 2-amino pyridines were compared with those of the simple host systems 14 and 15 in order to evaluate the influence of the attached resorcarene host. (c) 2008 Elsevier Ltd. All rights reserved ...
Background: The COVID-19 is a pandemic viral infection with a high morbidity rate, leading to many worldwide deaths since the end of 2019. The RBD (Receptor Binding Domain) of SARS-CoV-2 through its spike utilizes several host molecules to enter host cells. One of the most important ones is the angiotensin-converting enzyme 2 (ACE2), an enzyme normally engaged in renin angiotensin pathway and is responsible for hypertension regulation. As different articles have analyzed separate compounds which can bind ACE2 as the potential virus entry blockers, and each one with a different molecular docking algorithm, in this study we compared all candidate compounds individually as well as their combinations using a unique validated software to introduce most promising ones.. Methods: We collected and prepared a list of all available compounds which potentially can inhibit RBD binding site of the ACE2 from different studies and then reanalyzed and compared them using the Patchdock (ver. 1.3) as a suitable ...
Combining population genomic data with clinical information on the human IgG response to pneumococcal proteins provides a unique insight into the complex immunological interaction between host and pathogen. The continuous distribution of IgG binding values suggests that adaptive immunity responds to many antigens in both the core and the accessory genome. The most immunogenic proteins had physical properties expected to be associated with antibody binding: signal peptides, including those with a YSIRK motif, for secretion out of the bacterial cell; large size; and a lipoprotein processing motif, LPXTG sortase processing motif or CBD for surface attachment. The great majority of the ABTs either were variants of the diverse PspA, PspC, ZmpA, and ZmpB proteins or could be grouped into surface-exposed roles in host molecule adhesion or degradation, cell wall metabolism, or solute binding for transport. Despite the proteins on the microarray being expressed in vitro, detected ABTs included examples ...
INTRODUCTION. Structure-based drug design seeks to identify and optimize specific attractive interactions between two partner molecules in biological systems between ligands and their host molecules, typically proteins. The simple answer to whats holding the industry back in terms of adoption of latest drug discovery techniques is Education. There simply arent enough individuals trained on the use of Proteomics, Virtual Screening, Molecular Docking, Simulations, Dynamics and ADMET- multidisciplinary approaches, which is why we continue to offer courses, for both novice and experienced users, on the use of this technology as it applies to their research functions.. This 1 day training course will focus on the use of efficient technologies used in the discovery & designing of Drugs on the basis of the biological targets critical to the disease condition.. During this course, you will be introduced to basic principles of Rational Drug Design along with Proteomics in Drug Discovery. The course ...
These data show that there is an increasing potency of then-alkanol series for stabilizing BSA, but that the low aqueous solubility of the members longer than C10 limit the occupancy of n-alkanol binding sites, despite progressively increasing binding constants. For a soluble protein that does not significantly bind the alcohols studied, i.e., myoglobin, a progressive increase in potency for destabilization was observed until, again, a water solubility-limited cutoff effect occurred at about C10. Taken together, these results strongly suggest that solubility issues dominate then-alkanol cutoff effect. This is consistent with the observed shift in cutoff point in other homologous series. For example, relative to the C13-14 in vivo cutoff point for the saturatedn-alkanols, the less soluble n-alkane series have a shorter cutoff point (C10; Miller and Alifimoff, 1998), and the more soluble unsaturated n-alkanol series have a longer cutoff point (C15; Pringle et al., 1981). Also, similar in vivo ...
1OT1: The fully conserved Asp residue in Conserved sequence region I of the alpha-amylase Family is crucial for the Catalytic Site Architecture and Activity
The arrangement of the glucose units in the three different forms of cyclodextrin are shown in figure 26. The mouth of the torus-shaped cyclodextrin molecule has a larger circumference than at the base and is linked to secondary hydroxyl groups of the C2 and C3 atoms of each glucose unit (see figure 27). The primary hydroxyl groups are located at the base of the torus on the C6 atoms. As these hydroxyl groups are free to rotate, they partially block the base aperture. The size of the cavity increases with increasing number of glucose units (figure 26).The secondary hydroxyl groups can be reacted with appropriate reagents to introduce additional and different interactive character to the cyclodextrin molecule. The strong chiral selectivity of the cyclodextrins structures is thought to arise from the many chiral centers they contain (e.g., b-cyclodextrin has 35 stereogenic centers). The cyclodextrins are probably the most effective chirally selective stationary phases presently available for the ...
The solubility of natural cyclodextrins is very poor and initially this prevented cyclodextrins from becoming effective complexing agents. In the late 1960s, it was discovered that chemical substitutions at the 2-, 3-, and 6-hydroxyl sites would greatly increase solubility. The degree of chemical substitution and the nature of the groups used for substitution determine the final maximum concentration of cyclodextrin in an aqueous medium. Most chemically modified cyclodextrins are able to achieve a 50% (w/v) concentration in water.. Cavity size is the major determinant as to which cyclodextrin is used in complexation. Fit is critical to achieving good incorporation of cyclodextrins. α-Cyclodextrins have small cavities that are not capable of accepting many molecules. γ-Cyclodextrins have much larger cavities than many molecules to be incorporated, and cyclodextrin hydrophobic charges cannot effectively interact to facilitate complexation. The cavity diameter of β-cyclodextrins has been ...
article{7ad5f90a-94c1-4c5e-b086-8e73a88d96b6, abstract = {,p,Helicobacter pylori is an important human pathogen and a common cause of peptic ulcers and gastric cancer. Despite H. pylori provoking strong innate and adaptive immune responses, the bacterium is able to successfully establish long-term infections. Vitronectin (Vn), a component of both the extracellular matrix and plasma, is involved in many physiological processes, including regulation of the complement system. The aim of this study was to define a receptor in H. pylori that binds Vn and determine the significance of the interaction for virulence. Surprisingly, by using proteomics, we found that the hydrogen peroxide-neutralizing enzyme catalase KatA is a major Vn-binding protein. Deletion of the katA gene in three different strains resulted in impaired binding of Vn. Recombinant KatA was generated and shown to bind with high affinity to a region between heparin-binding domain 2 and 3 of Vn that differs from previously characterised ...
Have you wondered whether Febreze actually removes odors or whether it just covers them with a perfume? Have you wondered how it works? Heres the lowdown on Febreze. Its a product that was invented by Procter & Gamble and introduced in 1996. The active ingredient in Febreze is beta-cyclodextrin, a carbohydrate. Beta-cyclodextrin is an 8-sugar ringed molecule that is formed via an enzymatic conversion of starch. The cyclodextrin molecule sort of resembles a donut. When you spray Febreze, the water in the product partially dissolves the odor, allowing it to form a complex inside the hole of the cyclodextrin donut shape. The stink molecule is still there, but it cant bind to your odor receptors, so you cant smell it. Depending on the type of Febreze youre using, the odor might simply be deactivated or it might be replaced with something nice-smelling, like a fruity or floral fragrance. As Febreze dries, more and more of the odor molecules bind to the cyclodextrin, lowering the concentration ...
The synthesis and structural analysis of two novel families of three-component reversible redox cycles [(C2B9H11)M(m-SPh)2]2nPPNn (M = Mo, n = 2-, 2; 1-, 3; 0, 4; and M = W, n = 2-, 6; 1-, 7; 0, 8), where the cleavage and re-formation of the carborane cage C-C bond is observed during the redox reaction, are reported. Electronic saturation of the metal center (18e center) and the lack of bulky substituents on the carborane cage suggest that the deformed carborane cages in 2·PPN2, 6·PPN2, and 7·PPN invoke a new kind of deformed cage (semicloso framework). The XPS results show that the unprecedented competition for electron density between the metal center and the carborane cage is involved in the cleavage and formation of the carborane C-C bond. ...
3BMV: Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution.
Polyelectrolyte multilayers assembled from hyaluronic acid (HA) and poly-l-lysine (PLL) are most widely studied showing excellent reservoir characteristics to host molecules of diverse nature; however, thick (HA/PLL)n films are often found cell repellent. By a systematic study of the adhesion and proliferation of various cells as a function of bilayer number n a correlation with the mechanical and chemical properties of films is developed. The following cell lines have been studied: mouse 3T3 and L929 fibroblasts, human foreskin primary fibroblasts VH-Fib, human embryonic kidney HEK-293, human bone cell line U-2-OS, Chinese hamster ovary CHO-K and mouse embryonic stem cells ...
1cdg: Nucleotide sequence and X-ray structure of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 in a maltose-dependent crystal form.
Branched cyclodextrins are produced by the pyrolysis of cyclodextrins. The temperature range is 135 C. to 220 C. using equipment suitable for making British gum and other starch dextrins.
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Hi everyone.... Thanks to all of you who responded to my article request.......& heres another question Does anyone know of a staining method that would demonstrate the limit dextrin, after amylase digestion in FFPE tissue..... Thanks WAY in advance.... Good Weekend to all.... Luis _______________________________________________ Histonet mailing list [email protected] http://lists.utsouthwestern.edu/mailman/listinfo/histonet ...
Shop Inactive beta-amylase ELISA Kit, Recombinant Protein and Inactive beta-amylase Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
Formation of maltosyl cyclodextrins from mixtures of maltose and cyclodextrins by reverse reactions of Flavobacterium isoamylase and Klebsiella pullulanase was experimented and it was found that Klebsilla pullulanase produced 50.4 mg maltosyl alpha-cyclodextrin, 35.0 mg maltosyl beta-cyclodextrin and 55.4 mg maltosyl gamma-cyclodextrin per ml of reaction mixture, whereas Flavobacterium isoamylase did not form maltosyl cyclodextrins. Optimum conditions for formation of maltosyl beta-cyclodextrin by Klebsiella pullulanase were pH 4, 50 degrees C reaction temperature and proportion of substrate 100 mg beta-cyclodextrin/600 mg maltose per ml ...
Novelty, in brief, is represented by the intended elaboration of carborane, heteroborane and metallaborane compounds as active-site inhibitors of CA isoenzymes. All currently used inhibitors anhydrase inhibitors contain a sulfonamide or a sulfamate moiety connected to so called ring structure which is usually a 5- or 6-membered aromatic ring or conjugated ring system containing nitrogen, oxygen, and/or sulfur heteroatoms. The ring structure bears characteristics or functionality which modulates the affinity toward certain CA isoform. The use of three-dimensional boron cluster is a novel approach in development of isoform-specific CA inhibitors. Selected sulfamides incorporating cluster with inhibitory effects toward CAs (IC50 values in low micromolar and submicromolar range, some of the inhibitors being more than 50-times more selective toward the tumor specific CAIX than for CAII abundantly present in normal tissues ...
β-N-acetylhexosaminidase exhibits a relatively high activity in human epididymis. Its isoenzymatic profile and immunological properties led us to conclude that the increased activity was not due to the expression of an isoform unrelated to the HEX A and B present in other human tissues. Measurement of enzyme levels in the three distinct epididymal regions revealed that in any given sample, activity was higher in the caput than in the corpus or cauda. Moreover, we found a striking correlation between β-HEX activity in the caput region and concentrations of blood testosterone, suggesting a possible involvement of the hormone in modulating enzyme expression. Since the caput epididymis plays a role in the maturation of sperm cells, our data may be an indication that β-HEX activity in the caput has a physiological relevance in human epididymis functions.. ...
Treatment of Oil in Water Emulsions by Ceramic-Supported Polymeric Membranes. A novel membrane was developed by growing polymer chains from the surface of a porous ceramic support, resulting in a composite membrane which combines the mechanical properties of the inorganic membrane with the selective interactions of the polymer. The configuration of the grafted polymer brush layer is determined by solvent - polymer interactions, with a hydrophilic polymer being stretched away from the surface by aqueous solutions and collapsed against the surface by organic solvents. This behavior of the grafted chains provides Ceramic-Supported Polymeric (CSP) membranes with unique properties for certain water treatment applications. One application envisioned for these CSP membranes, in which the selectivity is influenced by interactions between the solvent and the grafted polymer, is the cross-flow filtration of an oil-in-water emulsion. In this case, a hydrophilic grafted polyvinylpyrrolidone (PVP) brush layer
In the past years, cyclodextrins (CDs) became more and more an important excipient for drug formulations. The main use of CDs in ophthalmic drug delivery is to increase the water solubility of lipophilic drugs, to modify drug bioavailability and to reduce ocular irritation. In the present study, the corneal permeability of different betablockers (in part combined with pilocarpine) in the presence of alpha-CD and hydroxypropylated (HP) alpha-, beta- and gamma-CD was examined. Addition of CDs often led to significant changes in permeation parameters, compared to CD-free solutions. The prodrug mycophenolate mofetil and its active drug mycophenolic acid (MPA) were solubilized by HP-beta-CD. The intraocular availability of these solutions was studied in the rabbit eye in vivo in comparison to a MMF-suspension. Applying MMF/HP-beta-CD-solution, the MPA level in cornea and aqueous humour (after 60 min) turned out to be significant higher than those of the MMF-suspension. In addition, for the extremely ...
A new technique to produce very small magnetic nanoparticles of maghemite (gamma-Fe(2)O(3)) is presented. The particles form and precipitate in the presence of the oligosaccharide gamma-cyclodextrin and in the final product remain entrapped in tiny pseudo-single crystals of the organic host. Evidence of nanosized particles embedded in the organic crystal was obtained by HR-TEM studies that showed the occurrence of uniformly dispersed particles with average diameter of 18 Angstrom. The resulting objects gave diffraction patterns with the same spacing as that of cyclodextrin crystals without iron. The magnetic properties were investigated by ZFC-FC magnetizations, hysteresis loops, and ac susceptibility measurements. The compound presents a complex magnetic behavior that deviates from that predicted on the basis of the classic single domain particle model. The deviation is ascribed to the complex properties of the surface, which, for such small sizes, plays the major role in determining the total ...
TY - JOUR. T1 - Photomodulated Supramolecular Chirality in Achiral Photoresponsive Rodlike Compounds Nanosegregated from the Helical Nanofilaments of Achiral Bent-Core Molecules. AU - Kim, Kibeom. AU - Kim, Hanim. AU - Jo, Seong Yong. AU - Araoka, Fumito. AU - Yoon, Dong Ki. AU - Choi, Suk Won. PY - 2015/10/14. Y1 - 2015/10/14. N2 - We prepared a nonchiral mixture of achiral bent-core molecules and photoresponsive rodlike liquid crystalline (LC) molecules. With the help of the isothermal photochemical nematic (N)-isotropic (Iso) phase transition of the photoresponsive rodlike LC molecules, the corresponding phase transition from a dark conglomerate BX phase to another distinguishable dark conglomerate B4 phase took place in the mixture. A large circular dichroism (CD) signal originating from supramolecular chirality was detected in the initial BX phase. On the other hand, the detected CD signal was decreased in the B4 phase after UV irradiation. Interestingly, the decreased CD signal could be ...
TY - JOUR. T1 - Interactions between cyclodextrins and cell-membrane phospholipids. AU - Szejtli, J.. AU - Cserháti, T.. AU - Szögyi, M.. PY - 1986. Y1 - 1986. N2 - The interactions between cyclodextrins (CDs) and selected cell membrane phospholipids, liposomes and human erythrocytes were studied. Non-methylated cyclodextrins did not influence the differential scanning calorimetric behaviour of phospholipids and did not increase the permeability of dipalmitoyl-phosphatidyl-choline liposomes. Dimethyl- and trimethyl- β-CD interacted with the phospholipids but the effect was negligible compared to the effect of valinomycin. Reversed-phase thin-layer chromatography revealed complex formation with dimethyl-β-cyclodextrin, but not with others. The addition of cyclodextrins up to 10-2 mol litre-1 concentration did not modify the active or passive alkali ion transport of human erythrocytes, however, higher concentrations of added β-cyclodextrin especially dimethyl-β-cyclodextrin resulted in ...
As expected the addition of enzymes boosted attenuation. Beano seems to digest more dextins than a malt extract. I wonder to what extent the difference is caused by limit dextrins (1-6 glucose links), which can only be broken by limit dextrinase, an enzyme which likely did not survive the 30 min mash at 60 C. Beanos glucoamylase is likely able to cleave both the 1-4 and the 1-6 links found in starch leaving only glucose and no limit dextrins.. It was surprising, however, that even with enzyme use during fermentation the apparent attenuation stayed in the mid 80s. This suggests that the low wort fermentability may not have been the result of incomplete starch and dextrin break-down during the mash. After all, I was going for very fermentable wort and held 30 min rests at 55 C, 63 C and 65 C followed by a 45 min rest at 72 C. I was expecting to get an attenuation limit in the high 80s with this mash schedule.. There was also a drop in pH. I contribute this to the extended fermentation activity, ...
The desired gamma-CD based carrier greatly reduced DOXs toxicity in vitro: up to 95% toxicity reduction in KB human enpidermal carcinoma; up to 92% toxicity reduction in HCT116 colorectal carcinomar. Cellular DOX uptake was reduced 73% in muscle, 69% in kidney, 66% in liver, 65% in heart, 62% in brain, 53% in lungs as 25% in plasma in vivo. The carrier-DOX inclusion is highly stable under physiological temperature and pH as well as under a wide range of acidic conditions (pH 1.0~7.0); the encapsulated DOX is slowly released under hyperthermic conditions (up to 50°C). In the presence of MBs (0.1%, 1%, 2.5% and 5%) application of FUS with low mechanical indexes (0.24, 0.31 and 0.53), under which no thermal effect was observed, enhanced up to 3.89-fold of cellular drug uptake for encapsulated DOX in vitro. Optimal setup of MR parameters: TR/TE = 3180/96.3msec; bandwidth: 10.4 kHz; Field of View = 20×20cm; matrix: 384×384, NEX: 2; slice thickness: 2.0mm/1.0sp; number of slices: 8; frequency ...
Damage-associated molecular patterns (DAMPs) are chemically heterogeneous endogenous host molecules rapidly released from damaged or dying cells that incite a sterile inflammatory response mediated via pattern recognition receptors (PRRs). The sources of DAMPs are dead or dying cells or the extracellular matrix and can signal through the PRRs, the Toll-like receptors or cytosolic Nod-like receptors, culminating in nuclear factor kappa B (NF-kappa B) activation and pro-inflammatory cytokine secretion. Together, these molecules are involved in sterile inflammation and many are associated with rheumatic autoimmune diseases such as rheumatoid arthritis, systemic lupus erythromatosus, psoriatic arthritis and systemic sclerosis. These diseases are associated with inflammation and many danger signals are found in sites of sterile inflammation and mediate inflammation. The present review examines the role of DAMPs in rheumatic conditions and suggests avenues for their therapeutic modulation.. ...
A process for treating an emulsion or solution of water and oil or the like comprising the steps of (a) contacting said emulsion or solution with an inorganic salt; (b) contacting said emulsion or sol
TY - JOUR. T1 - In situ control of cell adhesion using photoresponsive culture surface.. AU - Edahiro, Edahiro. AU - Junchi, Junchi. AU - Sumaru, Sumaru. AU - Kimio, Kimio. AU - Tada, Tada. AU - Yuichi, Yuichi. AU - Ohi, Ohi. AU - Katsuhide, Katsuhide. AU - Takagi, Takagi. AU - Toshiyuki, Toshiyuki. AU - Kameda, Kameda. AU - Mitsuyoshi, Mitsuyoshi. AU - Shinbo, Shinbo. AU - Toshio, Toshio. AU - Kanamori, Kanamori. AU - Yoshimi, Yoshimi. AU - Yasuo., Yasuo.. PY - 2005/2/16. Y1 - 2005/2/16. M3 - Article. VL - 6. SP - 970. EP - 974. JO - Biomacromolecules. JF - Biomacromolecules. SN - 1525-7797. ER - ...
Dive into the research topics of In situ control of cell adhesion using photoresponsive culture surface. Together they form a unique fingerprint. ...
The photochem. behavior of alkyldeoxybenzoins $PhCOCHPhCH_2CH_2R$ (R = H, Me, Et, hexyl, decyl) has been investigated in isotropic org. solvents, in aq. cyclodextrin solns., and bound to cyclodextrin in the solid state. Norrish type I and type II reactions occur in these media and the product distribution resulting from these primary processes are dependent on the medium. In org. solvents, type I and type II products are obtained in equal amts. In aq. cyclodextrin soln., type II products are formed in large excess. In the solid state, type II products constitute more than 90% of the product distribution. Ratios of products resulting from elimination and cyclization from the type II 1,4-diradical are also altered by the host cyclodextrin. Conformational and super-cage effects have been invoked to rationalize the dramatic alteration of the photobehavior of alkyldeoxybenzoins by cyclodextrin.. ...
Different from EC 3.2.1.142 (limit dextrinase) in its action on glycogen, and its rate of hydrolysis of limit dextrins. Its action on amylopectin is complete. Maltose is
TY - GEN. T1 - Branching of cyclodextrins with various mono-, di-, and tri-saccharides by Bacillus acidophilus pullulanase.. AU - Madsen, U.. AU - Larsen, Kim Lambertsen. PY - 2002. Y1 - 2002. KW - Bioteknologi. KW - Bioteknologi. M3 - Article in proceeding. BT - Third Nordic Starch network Symposium. PB - Denmark.. ER - ...
The perspective of adding stimuli-response to isoporous membranes stimulates the development of separation devices with pores, which would open or close under control of environment chemical composition, temperature or exposure to light. Changes in pH and temperature have been previously investigated. In this work,
A major factor in the survival of an organism is its ability to communicate with and respond to its environment. Among the environmental factors is a portion of the electromagnetic spectrum, from...
The preparation and characterization of a supramolecular host-guest inclusion complex between a fluorescent indolizinyl-pyridinium salt and β-cyclodextrin is reported. The formation of the inclusion complex was investigated by ESI-MS experiments, transmission electron microscopy, Jobs plot investigations an
We previously reported that polyamidoamine STARBURST dendrimer (generation 3, G3) (dendrimer) conjugate with α-cyclodextrin (α-CyD) having an average degree of substitution of 2.4 of α-CyD (α-CDE) provided remarkable aspects as novel carriers for
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Zhang, W. et al. ORGN 414-Folding polyrotaxanes using secondary noncovalent bonding interactions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, (AMER CHEMICAL SOC 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2008). ...
Zhang, W. et al. ORGN 414-Folding polyrotaxanes using secondary noncovalent bonding interactions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, (AMER CHEMICAL SOC 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2008). ...
Publication Details (including relevant citation information): Nociari, M.M., Lehmann, G.L., Perez Bay, A.E., Radu, R.A., Jiang, Z., Goicochea,
[102 Pages Report] Check for Discount on Global Dextrin Sales Market Report 2017 report by QYResearch Group. In this report, the global Dextrin market is valued at...
GlycoDrive™ was created with Highly Branched Cyclic Dextrin to be a high-performance source of carbohydrate super-fuel for athletes.
Fukaya, H; Iimura, A; Hoshiko, K; Fuyumuro, T; Noji, S; Nabeshima, T (Aug 2003). "A cyclosporin A/maltosyl-alpha-cyclodextrin ...
The fluorescence of these sulfonamide adducts can be enhanced by adding alpha-cyclodextrin. Dansyl chloride is unstable in ...
"Self-assembled supramolecular hydrogels formed by biodegradable PEO-PHB-PEO triblock copolymers and alpha-cyclodextrin for ... By combining ferrocene dimer with β-cyclodextrin dimer, a redox-control supramolecular polymers system has been proposed as a ... Akira Harada was one of the firstwhorecognize the importance of combining polymers and cyclodextrins. Feihe Huang showed an ... cyclodextrins/adamantane derivatives, and pillar arene/imidazolium derivatives [30-33]. When the monomers are "heteroditopic", ...
... and alpha-cyclodextrin. Challenges include reagent cost and the efficiency of gold recovery. Thiourea has been implemented ...
Two maltose molecules also bind in the cleft, one sharing a binding site with alpha-cyclodextrin, and the other sitting more ... The 3D structure of a complex of soybean beta-amylase with an inhibitor (alpha-cyclodextrin) has been determined to 3.0A ... beta alpha)8 fold. The interface of the two domains, together with shorter loops from the (beta alpha)8 core, form a deep cleft ... preliminary chain tracing of the complex with alpha-cyclodextrin". Journal of Biochemistry. 112 (4): 541-6. doi:10.1093/ ...
Mono-, Oligo- und Polyrotaxane mit Cucurbituril und gemischte Polyrotaxane mit Cucurbituril und alpha-Cyclodextrin mittels ... U.S. Patent 6,365,734 The complex formation of a, w-dicarboxylic acids and a, w-diols with cucurbituril and a-cyclodextrin. the ... Other common molecular capsules that share a similar molecular shape with cucurbiturils include cyclodextrins, calixarenes, and ...
... as supramolecular or covalent bonding of cyclodextrins to alpha-hemolysin demonstrates. An ion channel can be characterized by ... Other substituted β-cyclodextrins have since been reported, including thiol-modified cyclodextrins, an anion-selective ... Chui, J. K. W.; Fyles, T. M. (May 2010). "Apparent fractal distribution of open durations in cyclodextrin-based ion channels". ... The first synthetic ion channel was constructed by partial substitution on the primary rim of β-cyclodextrin. ...
... cyclodextrins MeSH D09.698.365.855.400.375.222 - alpha-cyclodextrins MeSH D09.698.365.855.400.375.333 - beta-cyclodextrins MeSH ... D09.698.365.855.400.375.444 - gamma-cyclodextrins MeSH D09.698.365.855.500 - hetastarch MeSH D09.698.365.855.750 - inulin MeSH ...
... alpha-cyclodextrins MeSH D04.345.103.333 - beta-cyclodextrins MeSH D04.345.103.444 - gamma-cyclodextrins MeSH D04.345.241.308 ... 20-alpha-dihydroprogesterone MeSH D04.808.745.745.654.829.395 - hydroxyprogesterones MeSH D04.808.745.745.654.829.395.400 - 17- ... 5-alpha-dihydroprogesterone MeSH D04.808.745.558.050 - alfaxalone alfadolone mixture MeSH D04.808.745.558.783 - ... alpha-hydroxyprogesterone MeSH D04.808.745.745.654.829.614 - medroxyprogesterone MeSH D04.808.745.745.654.829.614.500 - ...
... hydrolysis of m-tert-butylphenyl acetate is accelerated in the presence of 2-benzimidazoleacetic acid and alpha-cyclodextrin, ... developed a catalyst based on a beta-cyclodextrin carrying two imidazole groups. This cyclodextrin catalytic system mimics ... Cyclodextrins have rigid ring structure, hydrophilic surface, and hydrophobic cavity on the inside; therefore, they are capable ... From the early 1970s, cyclodextrins have been extensively studied for its encapsulation properties and used as binding sites in ...
Water Molecule in Hydrophobic Surroundings: Structure of alpha-Cyclodextrin-Hexahydrate (C6H10O5)6·6H2O, Nature, 1972 Circular ...
"Selective isolation of gold facilitated by second-sphere coordination with alpha-cyclodextrin" Nature Communications 2013, 4, ... Macrocyclic molecules such as cyclodextrins act often as the second coordination sphere for metal complexes. Coordination ...
GRN 000155, alpha-cyclodextrin;GRAS Notice No. GRN 000074, beta-cyclodextrin;GRAS Notice No. GRN 000046, gamma-cyclodextrin ... alpha)-cyclodextrin: 6 glucose subunits β (beta)-cyclodextrin: 7 glucose subunits γ (gamma)-cyclodextrin: 8 glucose subunits ... Alpha-, beta-, and gamma-cyclodextrin are all generally recognized as safe by the U.S. FDA. They have been applied for delivery ... This is very valuable especially for the food industry, as only alpha- and gamma-cyclodextrin can be consumed without a daily ...
α-Cyclodextrin is a hexasaccharide derived from glucose. It is related to the β- (beta) and γ- (gamma) cyclodextrins, which ... All cyclodextrins are white, water-soluble solids with minimal toxicity. Cyclodextrins tend to bind other molecules in their ... Then cyclodextrin glycosyltransferase (CGTase) is added for enzymatic conversion. CGTases produce diverse cyclodextrins. The ... The exterior surface of cyclodextrins is somewhat hydrophilic whereas the interior core is hydrophobic. α-Cyclodextrin is ...
... alpha-cyclodextrin glucanotransferase, alpha-cyclodextrin glycosyltransferase, beta-cyclodextrin glucanotransferase, beta- ... The systematic name of this enzyme class is 1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing). Other ... Rational design of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 to increase alpha-cyclodextrin ... cyclodextrin glycosyltransferase, gamma-cyclodextrin glycosyltransferase, cyclodextrin glycosyltransferase, cyclomaltodextrin ...
... where the readout of electrical signals occurred as nucleotides passed by alpha(α)-hemolysin pores covalently bound with ... cyclodextrin. However the subsequent commercial method, 'strand sequencing', sequenced DNA bases in an intact strand. Two main ...
At the moment, apiegnin and beta-cyclodextrin are thought to alleviate S.aureus pneumonia, whereas the antibodies of anti alpha ... It produces a ring-shaped complex called a staphylococcal alpha-hemolysin pore. In nature, Staphylococcus aureus secretes alpha ... There is a clear example of this: the pneumonia produced by S.aureus.[15] In this case, it has been proven that alpha-hemolysin ... Alpha-hemolysin from uropathogenic E. coli produces extra-intestinal infections and can cause cystitis, pyelonephritis, and ...
Cyclodextrin The cyclical dextrins are known as cyclodextrins. They are formed by enzymatic degradation of starch by certain ... Alpha) Limit dextrin is a short chained branched amylopectin remnant, produced by hydrolysis of amylopectin with alpha amylase ... that can be produced by enzymatic hydrolysis of the alpha-1,6 glycosidic bonds or debranching amylopectin. Amylodextrin colors ... which cannot hydrolyse the alpha-1,6 bonds at branch points. ( ... Cyclodextrins have toroidal structures formed by 6-8 glucose ...
Main article: Cyclodextrin. The cyclical dextrins are known as cyclodextrins. They are formed by enzymatic degradation of ... Alpha) Limit dextrin is a short chained branched amylopectin remnant, produced by hydrolysis of amylopectin with alpha amylase. ... Amylodextrin is a linear dextrin or short chained amylose (DP 20-30) that can be produced by enzymatic hydrolysis of the alpha- ... which cannot hydrolyse the alpha-1,6 bonds at branch points. ... Cyclodextrins have toroidal structures formed by 6-8 glucose ...
The maltogenic alpha-amylase is an enzyme which catalyses hydrolysis of (1-4)-alpha-D-glucosidic linkages in polysaccharides so ... which hydrolyses cyclodextrins. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G (July 1995). "Conserved ... as to remove successive alpha-maltose residues from the non-reducing ends of the chains in the conversion of starch to maltose ...
"Complex structures of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with acarbose and cyclodextrins demonstrate the multiple ... While most alpha-amylase enzymes only cleave alpha-1,4-linkages in their substrates, neopullulanase additionally cleaves alpha- ... 6-alpha-D-glucosylmaltose) The breakdown of the alpha-1,4- and alpha-1,6-glucosidic bonds of intermediates produced in addition ... These intermediates then have their alpha-1,4- and alpha-1,6-glucosidic bonds hydrolyzed to form additional panose along with ...
CPT is linked to a cyclodextrin-based polymer to form the investigational anti-cancer drug CRLX101. Like all other ... Then this intermediate is converted to indole glycerol phosphate, which interacts with the alpha-subunit of tryptophan (TSA) ... First, chorismate is converted to anthranilate by the alpha-subunit of anthranilate synthase (ASA). Anthranilate reacts with 5- ... and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring). Its planar ...
Johnson, Todd (July 1, 2013). "Illumina - A Deeper Look Into A Genetic Technology Investment". Seeking Alpha. Retrieved 12 ... cyclodextrin". Journal of the American Chemical Society. 105 (5): 1390-91. doi:10.1021/ja00343a063. "Anthony W. Czarnik, Ph.D ...
Chemically they are similar to the much smaller cyclodextrins, which are typically composed of 6, 7 or 8 glucose units. ... Takaha, T.; Yanase, M.; Okada, S.; Smith, S. M. (1993-01-15). "Disproportionating enzyme (4-alpha-glucanotransferase; EC 2.4. ... While the structures of cyclodextrins are planar circles, the structure of cycloamyloses with 10 to 14 glucose units were ... "Structures of the Common Cyclodextrins and Their Larger AnaloguesBeyond the Doughnut". Chemical Reviews. 98 (5): 1787-1802. doi ...
... where the readout of electrical signals occurring at nucleotides passing by alpha(α)-hemolysin pores covalently bound with ... cyclodextrin.[94] However the subsequently commercial method, 'strand sequencing' sequencing DNA bases in an intact strand. ...
Carotenes - color Alpha-carotene - color Beta-carotene - color Gamma-carotene - color Carrageenan - thickener, vegetable gum, ... artificial sweetener beta-cyclodextrin - emulsifier Lemongrass (Cymbopogon citratus, C. flexuosus, and other species) - Damiana ... antioxidant Dl-alpha-tocopherol (synthetic) - antioxidant Dodecyl gallate - antioxidant Echinacea - EDTA - Antioxidant, ...
... α-Cyclodextrin Cyclodextrin glycosyltransferase Cyclooxygenase Cyclopamine Cyclopiazonic acid Cysteine Cystine Cytidine ... Aequorin Aflatoxin Agar Alamethicin Alanine Albumins Aldosterone Aleurone Alpha-amanitin Alpha-MSH (Melaninocyte stimulating ... hormone) Allantoin Allethrin α-Amanatin, see Alpha-amanitin Amino acid Amylase (also see α-amylase) Anabolic steroid Anandamide ...
Crystal dissolvents have been under research, for example with cyclodextrin in atherosclerosis. Another approach would be to ... Finally, this activates the inflammatory response including the release of pro-inflammatory interleukin 1 alpha, interleukin 1 ... Paraproteins Amyloid beta peptides Amylin Transthyretin Alpha-synuclein Prions Uromodulin ASC speck complex Myoglobin Heme ...
The role of cholesterol in endocytosis of these types can be investigated by using methyl beta cyclodextrin (MβCD) to remove ... Cholesterol also activates the estrogen-related receptor alpha (ERRα), and may be the endogenous ligand for the receptor. The ...
beta-cyclodextrin - emülgatör. *Lemongrass. ÇDüzenle. *Kamelya yağı/ Daha çok güney Çin'de pişirme yağı olarak kullanılır. ... Dl-alpha-tocopherol (synthetic) - antioksidan. *Dodecyl gallate - antioksidan. EDüzenle. *EDTA - Antioksidan, ...
Cyclodextrin NP Solid tumours I Active Calando Pharmaceuticals NCT00689065 TD101 K6a (N171K mutation) Naked siRNA Pachyonychia ... RNAi silencing of alpha-amylase have also been used to decrease Aspergillus flavus fungal growth in maize which would have ... "RNA interference-based silencing of the alpha-amylase (amy1) gene in Aspergillus flavus decreases fungal growth and aflatoxin ...
... and complexation with cyclodextrins; among the latter, the complex with β-cyclodextrin has been found to have highly increased ... Alpha-lipoic acid (ALA). *Ascorbic acid (vitamin C). *Carotenoids (vitamin A). *Curcumin ... "A Study on the Bioavailability of a Novel Sustained-Release Coenzyme Q10-β-Cyclodextrin Complex". Integrative Medicine. 9 (1). ...
α-Amanatin, see Alpha-amanitin. *Aimínaigéad Amino acid. *Séaróideach anabalach Anabolic steroid ... α-Cyclodextrin. *Cyclodextrin glycosyltransferase. *Cyclopamine. *Cyclopiazonic acid. *Cysteine. *Cistín b2 Cystine. *Cytidine ...
A formulation of imatinib with a cyclodextrin (Captisol) as a carrier to overcome the blood-brain barrier is also currently[ ... and the beta crystalline form as opposed to the alpha or other form.[48]:3 and 4 In 1998, Novartis filed international patent ...
... if dosage forms are prepared that contain powdery cyclodextrin clathrates of these active ingredients."[82] The settlement of ... "Solid dosage forms that contain clathrates of 17.alpha.-ethinyl estradiol". Archived from the original on December 20, 2016 ...
"Selective isolation of gold facilitated by second-sphere coordination with alpha-cyclodextrin" Nature Communications 2013, 4, ... Macrocyclic molecules such as cyclodextrins act often as the second coordination sphere for metal complexes. [6][7] ...
August 25, 1998). "Solid dosage forms that contain clathrates of 17.alpha.-ethinyl estradiol". Archived from the original on ... if dosage forms are prepared that contain powdery cyclodextrin clathrates of these active ingredients." The settlement of the ...
From figure 5, we see that the L alpha-methyl amino acids do not directly act as a chiral directing group to generate the ... and the rate enhancement provided by binding to cyclodextrins produced major themes for study in modern organic and biological ... Researchers hoped that a second molecule of the alpha-methy amino acid could act as a directing group, however they found that ... It's worth noting that the alpha keto acid is believed to be formed from a Strecker-like reaction, shown below. ...
4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase. Other names in common use include branching ... cyclodextrin glucanotransferase (CGT), and branching enzyme. Shown by x-ray crystallography, glycogen branching enzyme has four ... 4-alpha-glucan branching enzyme 1, plant branching enzyme, alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase, and starch ... 1,4-alpha-glucan-branching enzyme, also known as brancher enzyme or glycogen-branching enzyme is an enzyme that in humans is ...
1 October 2010). "Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those ... where his team characterized the cytokines TNF-alpha and TNF-beta. Aggarwal was Chief of the Cytokine Research Section, ...
... cyclodextrin therapy. On January 23, 2013, a formal clinical trial to evaluate HPβCD cyclodextrin therapy as a treatment for ... cite journal ,vauthors=Rimkunas VM, Graham MJ, Crooke RM, Liscum L,title=TNF-{alpha} plays a role in hepatocyte apoptosis in ... the FDA granted Hydroxypropyl-beta-cyclodextrin orphan drug status and designated HPbCD cyclodextrin as a potential treatment ... Treatment with cyclodextrin has been shown to delay clinical disease onset, reduced intraneuronal storage and secondary markers ...
Family 1.D.60 The Alpha,Gamma-Cyclic Peptide (AGCP) Family 1.D.61 The Anionophoric 2,6-Bis(Benzimidazol-2-yl)Pyridine (ABBP) ... family 1.B.26 Cyclodextrin porin (CDP) family 1.B.31 Campylobacter jejuni major outer membrane oorin (MomP) family 1.B.32 ... Family 1.D.53 The alpha, gamma-Peptide Nanotube (a,gPepNT) Family 1.D.54 The potassium-selective Hexyl-Benzoureido-15-Crown-5- ... Ether Ion Channel (HBEC) Family 1.D.55 The Porphyrin-based Nanopore (PorNP) Family 1.D.56 The Alpha-Aminoisobutyrate (Aib) ...
Techno-economic analyses of specific alpha cyclodextrin production processes, presenting capital investment breakdown, raw ... ECONOMICS OF ALPHA-CYCLODEXTRIN PRODUCTION FROM CORN (ALPHA-CYCLODEXTRIN E12A) It presents the economics of alpha-Cyclodextrin ... Understand Alpha- Cyclodextrin production costs Industrial Process Economics About Alpha-Cyclodextrin Reports Coverage of Alpha ... ALPHA-CYCLODEXTRIN E11A) This report presents the economics of alpha-Cyclodextrin production from corn in the USA, using a ...
α-Cyclodextrin is a hexasaccharide derived from glucose. It is related to the β- (beta) and γ- (gamma) cyclodextrins, which ... All cyclodextrins are white, water-soluble solids with minimal toxicity. Cyclodextrins tend to bind other molecules in their ... Then cyclodextrin glycosyltransferase (CGTase) is added for enzymatic conversion. CGTases produce diverse cyclodextrins. The ... The exterior surface of cyclodextrins is somewhat hydrophilic whereas the interior core is hydrophobic. α-Cyclodextrin is ...
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.. ...
X-ray crystallographic analyses of pig pancreatic alpha-amylase with limit dextrin, oligosaccharide, and alpha-cyclodextrin. ... X-ray Crystallographic Analysis of Pig Pancreatic Alpha-Amylase with Alpha-cyclodextrin. *DOI: 10.2210/pdb3l2m/pdb ... Pancreatic alpha-amylase A 496 Sus scrofa EC#: 3.2.1.1 IUBMB Fragment: residues 16-511 Mutation: Q1X, A411D Gene Name(s): AMY2 ... ALPHA-D-GLUCOSE. C6 H12 O6 WQZGKKKJIJFFOK-DVKNGEFBSA-N ...
X-ray structure of the mutant E354A complexed with beta-cyclodextrin, and kinetic analyses on cyclodextrins. ... Studies on the hydrolyzing mechanism for cyclodextrins of Thermoactinomyces vulgaris R-47 alpha-amylase 2 (TVAII). ... Alpha Beta Alpha-Beta Barrel TIM Barrel Glycosidases A4. 1g1yA04. Mainly Beta Sandwich Immunoglobulin-like Golgi alpha- ... Alpha Beta Alpha-Beta Barrel TIM Barrel Glycosidases B4. 1g1yB04. Mainly Beta Sandwich Immunoglobulin-like Golgi alpha- ...
Inhibitory effects of alpha-cyclodextrin and its derivative against sucrose-induced hyperglycemia in an in vivo evaluation ... Cyclodextrins (CyDs) are cyclic oligosaccharides consisting of six to eight glucose residues. Administration of α-CyD (six ...
Cyclodextrin glucanotransferase (CGTase) catalyzed synthesis of dodecyl glucooligosides by transglycosylation using alpha- ... surfactant molecules were synthesized by cyclodextrin glucanotransferase from Bacillus macerans using either alpha-cyclodextrin ... surfactant molecules were synthesized by cyclodextrin glucanotransferase from Bacillus macerans using either alpha-cyclodextrin ... surfactant molecules were synthesized by cyclodextrin glucanotransferase from Bacillus macerans using either alpha-cyclodextrin ...
... and gamma-cyclodextrin dimers. Molecular dynamics studies of the solvent effect and free binding energies ... Interaction of native alpha-cyclodextrin, beta-cyclodextrin and gamma-cyclodextrin and their hydroxypropyl derivatives with ... Crystal structure of the gamma-cyclodextrin n-propanol inclusion complex; correlation of alpha-, beta-, gamma- cyclodextrin ... Alpha-, beta-, and gamma-Cyclodextrin dimers. Molecular modeling studies by molecular mechanics and molecular dynamics ...
Cyclodextrin glycosyltransferase (CGTase) is an enzyme of the alpha-amylase family, which uses a double displacement mechanism ... X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family ... X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family ... X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family ...
2013018332Cornstarch Replaces Cyanide In Clean New Gold Extraction Method Scientistα cyclodextrin gold extraction ... Cyclodextrin For Gold 2013 Theyre using alpha cyclodextrin to bind Gold cations selectively not the metal itself Think of ... gold extraction process alpha cyclodextrin pci pci October goldextractionprocessalphacyclodextrin CyclodextrinWikipedia (alpha) ... Alpha Pharma manufacturers amp suppliers MadeinChina madeinchina productssearch hotchinaproducts Alpha China Alpha Pharma ...
... alpha… denniscao. extraction of gold by using alpha cyclodextrin. May 14, 2013· Alpha-cyclodextrin is the gold medal winner, ... Selective Isolation of Gold by Alpha-Cyclodextrin on Vimeo. 2:41May 15, 2013· Selective Isolation of Gold by Alpha-Cyclodextrin ... Self-Assembled Monolayers of α-Cyclodextrin Derivatives on .... Various sulfur-modified alpha-cyclodextrin (alpha-CD) ... 15/05/2013· Tags: Alpha-cyclodextrin, Alpha-cyclodextrin gold mining, crude gold extraction toxic, cyanamide gold mining, ...
... _BioResources: Peer-reviewed online journal for lignocellulosic science Hubbe, M. A., and ... alpha cyclodextrin gold extraction. 06/Apr/2010. polysorbate 20 9005-64-5 - The Good Scents Company Food Additive: Functional ... Cyclodextrin - Wikipedia, the free encyclopedia Cyclodextrins are able to form host-guest complexes with hydrophobic molecules ... beta-cyclodextrin 7585-39-9 - The Good Scents Company Category: carrier solvents, encapsulating agent for food additives, ...
No: CDexA-011 This Product is available in multi-grams / kilogram pack size, please inquire at [email protected]cyclodextrin-shop.com ... Hexakis-(6-deoxy-6-mercapto)-alpha-Cyclodextrin. Product Name. : Hexakis-(6-deoxy-6-mercapto)-α-Cyclodextrin. ≥97%. ... Hexakis-(2,3,6-tri-O-benzoyl)-alpha-Cyclodextrin. Product Name. : Hexakis-(2,3,6-tri-O-benzoyl)-α-Cyclodextrin. ... Hexakis-(6-bromo-6-deoxy)-alpha-Cyclodextrin. Product Name. : Hexakis-(6-bromo-6-deoxy)-α-Cyclodextrin ≥97%. ...
Leading Molecular Weight of Alpha Cyclodextrin Manufacturers & Suppliers, find Molecular Weight of Alpha Cyclodextrin Factory ... China Molecular Weight of Alpha Cyclodextrin with High-Quality, ... Molecular Weight of Alpha Cyclodextrin * Alpha Cyclodextrin ... Home > Products > Natural Alpha Beta Gamma Cyclodextrin > Natural Alpha Cyclodextrin > Molecular Weight of Alpha Cyclodextrin ... Alpha-cyclodextrin is widely used in the drugs, food, flavor and cosmetics. Alpha-cyclodextrin is also widely used in the field ...
Branched cyclodextrins are produced by the pyrolysis of cyclodextrins. The temperature range is 135 C. to 220 C. using ... A six membered ring is called alpha cyclodextrin; seven, beta cyclodextrin; and eight, gamma cyclodextrin. These six, seven and ... The advantage of branched cyclodextrins over cyclodextrins and especially branched beta cyclodextrins over beta cyclodextrins ... A branched cyclodextrin wherein not all of the bonds between the branches and the cyclodextrin ring are alpha-1,6 bonds. ...
HP-alpha-, HP-beta- and HP-gamma-CyDs) as biocompatible solubilizers and stabilizers for oleic acid, a lipophilic absorption ... The potential use of three 2-hydroxypropyl ether derivatives of cyclodextrins ( ... The potential use of three 2-hydroxypropyl ether derivatives of cyclodextrins (HP-alpha-, HP-beta- and HP-gamma-CyDs) as ... HP-alpha-CyD , HP-beta- CyD. The bend structure due to a cis-double bond halfway along the acyl chain of oleic acid provided a ...
... aggregates were one of the most important factors that significantly influenced fiber formation during cyclodextrin ... the formation of hydroxypropyl-β-cyclodextrin (HPCD) nanofibers in electrospinning and the adsorption of organic molecules on ... Electrospinning of cyclodextrins: hydroxypropyl-alpha-cyclodextrin nanofibers. *Asli Celebioglu, Tamer Uyar. *Materials Science ... Electrospun Fibers of Cyclodextrins and Poly(cyclodextrins). *Alejandro Costoya, Angel Concheiro, Carmen Alvarez-Lorenzo ...
6-O-ALPHA-D-GLUCOSYL-BETA-CYCLODEXTRIN(92517-02-7) Density MSDS Formula Use,If You also need to 6-O-ALPHA-D-GLUCOSYL-BETA- ... ChemicalBook provide Chemical industry users with 6-O-ALPHA-D-GLUCOSYL-BETA-CYCLODEXTRIN(92517-02-7) Boiling point Melting ... Cyclooctapentylose Hydroxypropyl-beta-cyclodextrin BETA-CYCLODEXTRIN 2-Hydroxypropyl-β-cyclodextrin β-Cyclodextrin, sulfobutyl ... alpha-isomaltose 6-A-D-GLUCOPYRANOSYLMALTOTRIOSE beta-Cyclodextrin hydrate 6-O-ALPHA-D-GLUCOPYRANOSYL-D-GLUCITOL 6-O-ALPHA-D- ...
Be free to buy quality alpha cyclodextrin made in China with our factory. ... Qianhui Biological is one of professional alpha cyclodextrin manufacturers and suppliers in China with rich experience. ... Natural Cyclodextrin Main Beta Cyclodextrin Derivatives Other Beta Cyclodextrin Derivatives Alpha Cyclodextrin Derivatives ... High Standard Daily Chemical Field Additives Alpha Cyclodextrin. Name: alpha-cyclodextrin Other name : α-cyclodextrin ; ...
Essential Dietary Fiber - Alpha Cyclodextrin - Nuvexa - Inhibits Fat Absorption - 180 tablets - FREE US SHIPPING. Default Title ... FBCx®** Alpha-cyclodextrin 2 g*. Other ingredients: Croscarmellose sodium, stearic acid, magnesium stearate, silicon dioxide, ... Home › Essential Dietary Fiber - Alpha Cyclodextrin - Nuvexa - Inhibits Fat Absorption - 180 tablets - FREE US SHIPPING ... Essential Dietary Fiber contains the soluble fiber alpha-cyclodextrin, patented as FBCx®. Decades of preclinical and clinical ...
Be free to buy quality sulfobutylether alpha cyclodextrin made in China with our factory. ... Qianhui Biological is one of professional sulfobutylether alpha cyclodextrin manufacturers and suppliers in China with rich ... Natural Cyclodextrin Main Beta Cyclodextrin Derivatives Other Beta Cyclodextrin Derivatives Alpha Cyclodextrin Derivatives ... Sulfobutylether Alpha Cyclodextrin. *. Contact Us. Pharmaceutical Grade Excipients Embedding Medium Sulfobutylether Alpha ...
2 alpha-cyclodextrin][PF6][H2O]. Cyclodextrins as second-sphere ligands for transition metal complexes - The X-ray crystal ... 2 alpha-cyclodextrin][PF6][H2O], (D. R. Alston, A. M. Z. Slawin, J. F. Stoddart, and D. J. Williams), Angew. Chem. Int. Ed. ... Cyclodextrins as second-sphere ligands for transition metal complexes - The X-ray crystal structure of [Rh(cod)(NH3) ...
... cyclodextrins: Indigestibility and hypolipemic effect of alpha-cyclodextrin. J. Nutr. Sci. Vitaminol., 31, 209-223. Submitted ... each of 2 animals were given 14C-labelled alpha-cyclodextrin, -cyclodextrin or gelatinised potato starch by gavage as ... ANTENUCCI, R.N. & PALMER, J.K. (1984) Enzymatic degradation of alpha- and -cyclodextrins by Bacteroides of the human colon. J. ... See Also: Toxicological Abbreviations beta-Cyclodextrin (WHO Food Additives Series 35) beta-CYCLODEXTRIN (JECFA Evaluation) ...
... alpha-cyclodextrin A placebo comparator composed of the same acid resistant HPMC capsules filled with 300mg of alpha ...
Alpha-cyclodextrin Alpha-cyclodextrin, a non-digestible carbohydrate derived from corn, has received much attention for its ... Adiponectin levels rose in the alpha-cyclodextrin group but fell in the placebo group; and subjects in the alpha-cyclodextrin ... greater in the alpha-cyclodextrin group than the control group. Insulin and ApoB levels also fell in the alpha-cyclodextrin ... Alpha-cyclodextrin forms a complex with fats, and while it does increase excretion of fat in the stool, it does not appear to ...
Alpha-Cyclodextrin. Researchers have identified a natural fiber called alpha-cyclodextrin that selectively absorbs and ... Studies showed if alpha-cyclodextrin were taken three times daily during high-fat meals (2 g per meal), it could engulf as much ... Moreover, alpha-cyclodextrin has been shown to selectively reduce unhealthy fats while leaving alone the safer fats. In a ... Unlike conventional dietary fiber, which non-selectively binds fat in about a 1:1 ratio, a single gram of alpha-cyclodextrin is ...
Preparation and enzymatic hydrolysis of maltosyl-.ALPHA.-cyclodextrin. SAKANO Yoshiyuki , SANO Mutsumi , KOBAYASHI Tsuneo ... Hydrolysis of .ALPHA.-1,4- and .ALPHA.-1,6-glucosidic linkages in trisaccharides by the Thermoactinomyces vulgaris .ALPHA.- ... Structure of cyclodextrin glycosyltransferase complexed with a derivative of its main product β-cyclodextrin SCHMIDT A. K. ... X-Ray Structure of the Mutant E354A Complexed with β-Cyclodextrin, and Kinetic Analyses on Cyclodextrins Kondo Shin , Ohtaki ...
alpha-cyclodextrin functionalized CdS nanocrystals for fabrication of 2/3 D assemblies. (2006) in The journal of physical ... Water phase transfer of oleic capped semiconductor nanocrystals mediated by alpha-cyclodextrins. (2005) in Proceedings of SPIE ... a-Cyclodextrin functionalized CdS nanocrystals for fabrication of 2/3 D Assemblies. (2006) XIII International Cyclodextrin ... Cyclodextrin mediated phase transfer in water of organic capped CdS nanocrystals. (2004) 9th European Conference on Organised ...
... cyclodextrin has been studied.,/p,,p,,b,RESULTS,/b,The distribution behavior of alpha-cyclohexyl mandelic acid enantiomers in ... Resolution of alpha-cyclohexyl mandelic acid enantiomers by enantioselective extraction in Resolution of alpha-cyclohexyl ... cyclodextrin on the enantioselectivity.,/p,,p,,b,METHODS,/b,Resolution of alpha-cyclohexyl mandelic acid enantiomers by ... Full text: Available Index: WPRIM (Western Pacific) Main subject: Stereoisomerism / Tartrates / Chemistry / Beta-Cyclodextrins ...
alpha-Cyclodextrin. N. ADI not specifiedf. Sodium sulfate. S. ADI not specifiedf. ...
  • The potential use of three 2-hydroxypropyl ether derivatives of cyclodextrins (HP-alpha-, HP-beta- and HP-gamma-CyDs) as biocompatible solubilizers and stabilizers for oleic acid, a lipophilic absorption enhancer, was assessed in the nasal absorption of buserelin, an agonist of luteinizing hormone-releasing hormone, in rats. (nih.gov)
  • Other name : Sulfobutylether-α-cyclodextrin Abbreviation : SBEACD Grade : pharma grade, food grade Standard : enterprise standard Package: 500g/bag , 2kg/bag, 10kg/drum or customized Use : medical \ chemical Sulfobutylether alpha cyclodextrin is a derivatives of Apha. (cyclodextrinchina.com)
  • Other name : Sulfobutylether-α-cyclodextrin, SBEACD Appearance: White powder Grade : pharma grade, Cosmetic grade Standard : In-house standard Package: 500g/bag , 1kg/bag, 10kg/drum, 20kg/drum or customized Sulfobutylether alpha cyclodextrin is a derivatives of Apha. (cyclodextrinchina.com)
  • This paper presents a software to build theoretical models of cyclodextrin derivatives and evaluate their host:guest interactions, using a graphical user interface in an intuitive way. (springer.com)
  • The second module performs the docking calculations between the host (cyclodextrins and/or their derivatives) and guest molecules, using the AutoDock Vina program, and displays the final results of the modeled inclusion complexes, including graphs showing the distribution energy and intermolecular interactions present in the host:guest complex. (springer.com)
  • Aicart, E., Junquera, E.: Complex formation between purine derivatives and cyclodextrins: a fluorescence spectroscopy study. (springer.com)
  • A stable composition for removing unwanted molecules from a surface comprises low-degree of substitution cyclodextrin derivatives. (google.com.au)
  • The used cyclodextrins were native beta-cyclodextrin (beta-CD), its derivatives hydroxyethyl-beta-CD (HE-beta-CD), three hydroxypropyl-beta-CD (HP-beta-CD) with various degree of substitution and methyl-beta-CD (M-beta-CD), native alpha-cyclodextrin (alpha-CD), hydroxypropyl-alpha-CD (HP-alpha-CD) and hydroxypropyl-gamma-CD (HP-gamma-CD). (unboundmedicine.com)
  • The dipentylated derivatives of alpha, beta and gamma cyclodextrin show pronounced selectivity differences based on the size, shape and functionality of the analyte. (sigmaaldrich.com)
  • Publications] Yoshihisa MATSUI: 'Host-guest complexation of 6-deoxy-6-(1-pyridinio) derivatives of alpha-cyclodextrin (cyclomatohexaose) with inorganic anions in aqueous solution' Carbohydrate Research. (nii.ac.jp)
  • We report the effect of native cyclodextrins (alpha, beta, and gamma) and selected derivatives in modulating the self-assembly of the nonionic surfactant polyoxyethylene cholesteryl ether (ChEO(10)) and its mixtures with triethylene glycol monododecyl ether (C12EO3), which form wormlike micelles. (diva-portal.org)
  • The preferred perfume/cyclodextrin complexes, either alone or admixed with solvent (e.g., water), are preferably suspended in the carrier and then incorporated into solid, dryer-activated, fabric treatment (conditioning) compositions, preferably containing fabric softeners, more preferably cationic and/or nonionic fabric softeners. (google.ca)
  • and mixtures thereof, and wherein said cyclodextrin is capable of forming inclusion complexes with said active. (google.ca)
  • After discovering the needles, Liu screened six different complexes-cyclodextrins composed of rings of six (alpha), seven (beta) and eight (gamma) glucose units, each combined with aqueous solutions of potassium tetrabromoaurate (KAuBr 4 ) or potassium tetrachloroaurate (KAuCl 4 ). (phys.org)
  • From them we derived the stability constants of the inclusions complexes nimodipine-cyclodextrin (1:1) as well as the empirical linear equations for the calculation of the saturated nimodipine concentration at a given cyclodextrin concentration. (unboundmedicine.com)
  • Bethanis, K. Structural studies of the inclusion complexes of the (+)- and (-)-borneol enantiomers in alpha- and beta-cyclodextrin. (alfa.com)
  • Cyclodextrins (CyDs) are cyclic oligosaccharides consisting of six to eight glucose residues. (go.jp)
  • Alpha-cyclodextrins are ring-shaped oligosaccharides that have a hydrophilic exterior and a lipophilic cavity. (foodbusinessnews.net)
  • Cyclodextrins (CDs) are a family of cyclic oligosaccharides that are composed of α-1,4-linked glucopyranose subunits. (ncl.edu.tw)
  • Fructooligosaccharides (FOS) and other oligosaccharides such as cyclodextrins are gaining attention for their health benefits. (novozymes.com)
  • In order to develop artificial materials available for the selective separation of the nitrate ion from environmental water, cyclodextrins, cyclic oligosaccharides, were chemically modified with pyridinio or butylamino groups, and the host compounds were further modified to be solubilized in organic media or to be immobilized on polymers. (nii.ac.jp)
  • 2- O - d -Glucopyranosyl- l -ascorbic acid (AA-2G), a stable l -ascorbic acid derivative, is usually synthesized by cyclodextrin glycosyltransferase (CGTase), which contains nine substrate-binding subsites (from +2 to −7). (asm.org)
  • The first module builds theoretical models with more than one chemical structure to represent a cyclodextrin derivative. (springer.com)
  • 21. The composition of claim 1, wherein the host compound is one or more of a cyclodextrin or a cyclodextrin derivative. (patentgenius.com)
  • cyclodextrin derivative. (patentgenius.com)
  • 1. A composition for capturing unwanted molecules, said composition comprising low degree of substitution cyclodextrin derivative and a perfume material wherein said low-degree of substitution cyclodextrin derivative is selected from the group consisting of hydroxyalkyl cyclodextrin having an average degree of substitution of less than about 4.5, alkylated cyclodextrin having an average degree of substitution of less than about 6.0, and mixtures thereof. (google.com.au)
  • 2. A composition according to claim 1 wherein said low-degree of substitution cyclodextrin derivative is selected from the group consisting of hydroxyalkyl cyclodextrin having an average degree of substitution of less than about 4.5, alkylated cyclodextrin having an average degree of substitution of less than about 5.5, and mixtures thereof. (google.com.au)
  • Incorporates a phase consisting of a 2,6-di-O-pentyl-3-methoxy derivative of β-cyclodextrin. (sigmaaldrich.com)
  • To the KUHIMM they added low doses (six grams) of three different prebiotics: indigestible dextrin, alpha-cyclodextrin, and dextran. (naturalnews.com)
  • WACKER offers innovative antioxidants (CAVACURMIN ® , CAVAQ10 ® , HTEssence ® ) and a soluble dietary fiber - CAVAMAX ® W6 alpha-dextrin - for use in formulating novel food-supplement formulations (EU-verified health claim). (wacker.com)
  • CAVAMAX ® W6 alpha-dextrin is a natural-occurring cyclic oligosaccharide that is produced by WACKER via the enzymatic degradation of starch. (wacker.com)
  • AHCC Proprietary Blend - Shiitake mycelium extract 500mg Non-medicinal ingredients: alpha-cyclodextrin, dextrin, microcrystalline cellulose, Candelilla wax. (communitynaturalfoods.com)
  • Researchers designed a controlled human study on the metabolic effects of alpha-cyclodextrin on healthy volunteers. (thefreelibrary.com)
  • Then cyclodextrin glycosyltransferase (CGTase) is added for enzymatic conversion. (wikipedia.org)
  • Cyclodextrin glycosyltransferase (CGTase) is an enzyme of the alpha-amylase family, which uses a double displacement mechanism to process alpha-linked glucose polymers. (ubc.ca)
  • Cyclodextrins are natural starch-conversion products. (wikipedia.org)
  • Dodecyl glucooligosides, a class of interesting non ionic surfactant molecules were synthesized by cyclodextrin glucanotransferase from Bacillus macerans using either alpha-cyclodextrin (alpha-CD) or soluble starch as glycosyl donor and dodecyl beta-D-glucoside (C(12)G(1)) or dodecyl beta-D-maltoside (C(12)G(2)) as acceptor substrates. (lu.se)
  • Higher yields of coupling products were obtained using alpha-CD as donor, while more dispoportionation occurred with starch. (lu.se)
  • 14/05/2013· He found that it was alpha-cyclodextrin, a cyclic starch fragment composed of six glucose units, that isolates gold best of all. (ragusatelegraph.it)
  • 14/05/2013· Alpha-cyclodextrin, a cyclic starch fragment with six glucose molecules, is the best way to isolate gold, they found. (ragusatelegraph.it)
  • 17/01/2014· Scientists at the North Western University in Illinois are using alpha-cyclodextrin, a substance commonly extracted from corn starch, to recover gold. (ragusatelegraph.it)
  • It is produced by the action of the enzyme, cyclodextrin glycosyl transferase (CGT), on hydrolyzed starch syrups. (inchem.org)
  • 1984). In a preliminary comparative metabolism study in rats, groups each of 2 animals were given 14 C-labelled alpha-cyclodextrin, -cyclodextrin or gelatinised potato starch by gavage as approximately 2.5 ml of a 2.5% aqueous solution. (inchem.org)
  • Zhichang Liu, a postdoctoral fellow in Stoddart's lab and first author of the paper, took two test tubes containing aqueous solutions-one of the starch-derived alpha-cyclodextrin, the other of a dissolved gold (Au) salt (called aurate)-and mixed them together in a beaker at room temperature. (phys.org)
  • Novozymes Toruzyme® is the right tool for catalyzing the formation of alpha-, beta-, and gamma-cyclodextrins from starch. (novozymes.com)
  • Whether the end-product is high fructose syrup, dextrose, maltose, maltodextrin or polyols, the process starts with an alpha-amylase for starch liquefaction that can be applied under a wide range of conditions. (novozymes.com)
  • Kopecký F, Kopecká B, Kaclík P. [Dissolution of nimodipine in an aqueous solution of hydroxyethyl-beta-cyclodextrin and a review of solubility of nimodipine with cyclodextrins]. (unboundmedicine.com)
  • For drug delivery, this cyclodextrin confers aqueous solubility to hydrophobic drugs and stability to labile drugs. (wikipedia.org)
  • alpha cyclodextrins solubility is 1.27 g / 100ml and beta- cyclodextrins solubility is only 1.88 g / 100ml. (zycydextrin.com)
  • Smaller cavity and better water solubility make it has the larger applications than beta-cyclodextrin in some case. (zycydextrin.com)
  • In this range of cyclodextrin concentration, linear phase diagrams of nimodipine solubility in the cyclodextrin solutions were observed. (unboundmedicine.com)
  • 1. Know the capital investment required Examine the operating costs & raw materials consumption Alpha-Cyclodextrin is a polysaccharide and a multifunctional, soluble dietary fiber marketed for use as a fiber ingredient, an odor or flavor masking agent, and for emulsification applications. (slideshare.net)
  • All cyclodextrins are white, water-soluble solids with minimal toxicity. (wikipedia.org)
  • The nimodipine dissolution was studied as a function of time (up to 14 days) and cyclodextrin concentration up to 0.07 mol/l, excepting the less soluble beta-CD. (unboundmedicine.com)
  • 1) Mono-[6-(1-pyridinio)-6-deoxy]-cyclodextrin was perbenzoylated to give a host compound soluble in chloroform. (nii.ac.jp)
  • For applications requiring pure compounds like C(12)G(7), synthesis using alpha-CD is advantageous. (lu.se)
  • Synthesis of β-Cyclodextrin-Based Electrospun Nanofiber Membranes for Highly Efficient Adsorption and Separation of Methylene Blue. (semanticscholar.org)
  • Cyclodextrins tend to bind other molecules in their quasi-cylindrical interiors. (wikipedia.org)
  • In this paper, the formation of hydroxypropyl-β-cyclodextrin (HPCD) nanofibers in electrospinning and the adsorption of organic molecules on the HPCD nanofiber were studied. (semanticscholar.org)
  • As a result of its cyclic structure, -cyclodextrin has the ability to form inclusion compounds with a range of molecules, generally of molecular mass of less than 250. (inchem.org)
  • FDA states the CPs will be reviewed on a rolling basis, with the most recent CP submitted in December 2019 for alpha-cyclodextrin. (lexology.com)
  • Monochlorotriazinyl--cyclodextrin (CAS 187820-08-2) Market Research Report 2017 aims at providing comprehensive data on monochlorotriazinyl--cyclodextrin market globally and regionally (Europe, Asia, North America, Latin America etc. (marketpublishers.com)
  • Monochlorotriazinyl--cyclodextrin (CAS 187820-08-2) Market Research Report 2017 contents were worked out and placed on the website in December, 2017. (marketpublishers.com)
  • Please note that Monochlorotriazinyl--cyclodextrin (CAS 187820-08-2) Market Research Report 2017 is a half ready publication and contents are subject to change. (marketpublishers.com)
  • Analytes studied include polyethylene glycol, polyethylene oxide dimethyl ether, cyclic polyethylene oxide and alpha-cyclodextrin. (eurekamag.com)
  • Its favorable effect on glucose metabolism may be due to an ability to complex and inhibit pancreatic alpha-amylase. (franceswilliamsmd.com)
  • and mixtures thereof, the weight ratio of said active/cyclodextrin inclusion complex to said solid polyalkylene glycol carrier material being from about 1:1 to about 1:5. (google.ca)
  • In a vacuum, MD simulations provided the head-to-head orientation as the most stable orientation for the three CyDs, while in aqueous solution the, the head-to-tail orientation was found to be the most stable for the alpha-CyD dimer and the tail-to-tail orientation the most stable for the beta- and gamma-CyD dimers. (eurekamag.com)
  • 1963). -Cyclodextrin, purity >77%, and glucose, uniformly labelled with 14 C, were administered to rats by gavage as solutions in 20% aqueous dextran at dose levels of 13 mg/kg bw for glucose and 36 and 313 mg/kg bw for -cyclodextrin. (inchem.org)
  • The results of a comprehensive study of the dissolution of the calcium antagonist nimodipine in aqueous solutions of nine cyclodextrins are reported. (unboundmedicine.com)
  • 2) Mono-[6-(1-pyridinio)-6-deoxy]-cyclodextrin was immobilized on bridge type or pendant type polymers, and the adsorption of the nitrate ion on the host polymers was examined in an aqueous solution. (nii.ac.jp)
  • 3) All the C(6)-OH groups of cyclodextrins were replaced with butylamino groups, and an ability of the resulting hosts to bind the nitrate ion was examined in an acidic aqueous solution. (nii.ac.jp)
  • It is related to the β- (beta) and γ- (gamma) cyclodextrins, which contain seven and eight glucose units, respectively. (wikipedia.org)
  • EXPLANATION -Cyclodextrin is a cyclic heptamer composed of seven glucose units joined "head-to-tail" by alpha-1,4 links. (inchem.org)
  • α-Cyclodextrin is a dietary fiber being researched as a potential weight loss supplement due to its ability to bind 9 times its weight in fat. (ragusatelegraph.it)
  • To establish a resolution method for alpha-cyclohexyl mandelic acid enantiomers by enantioselective extraction and to observe the effects of all kinds of tartaric esters , pH , the concentration of D-tartaric esters and beta- cyclodextrin on the enantioselectivity. (bvsalud.org)
  • The effects of all kinds of tartaric esters , pH , the concentration of D-tartaric esters and beta- cyclodextrin on the enantioselectivity has been examined in the two-phase. (bvsalud.org)
  • Structure and thermodynamics of alpha-, beta-, and gamma-cyclodextrin dimers. (eurekamag.com)
  • The alpha-, beta-, and gamma-cyclodextrin (CyDs) dimers were studied by molecular dynamics (MD) simulations in water as an explicit solvent. (eurekamag.com)
  • When added to wormlike micelles of ChEO(10) and C12EO3, native beta-CD, 2-hydroxyethyl-beta-CD (HEBCD), and a sulfated sodium salt of beta-CD (SULFBCD) induce a substantial increase of the viscoelasticity, while methylated CDs rupture the micelles, leading to a loss of the viscosity, and the other CDs studied (native alpha- and gamma- and hydroxypropylated CDs) show a weak interaction. (diva-portal.org)
  • With the aid of gamma-cyclodextrin CAVACURMIN ® , the bioavailability of curcumin can be increased by a factor of around 40 compared to conventional extracts. (wacker.com)
  • Likewise, the bioavailability of coenzyme Q10 can be increased 18-fold by complexing it with gamma-cyclodextrin CAVAMAX ® CoQ10. (wacker.com)
  • CAVAMAX ® W6 alpha-cyclodextrin and W8 gamma-cyclodextrin can effectively mask unpleasant odors and flavors of functional substances in foods. (wacker.com)
  • The concentration of beta- cyclodextrin and D-tartaric ester had visible effect on the enantioselectivity. (bvsalud.org)
  • Cholesterol depletion from LLC-MK2 cells by methyl-beta cyclodextrin treatment resulted in a marked increase in the production of both HVJ from the infected cells and virus-like particles from M-gene-transfected cells. (deepdyve.com)
  • Rajamohan, R. 2018-05-22 00:00:00 The supramolecular host-guest inclusion complex of Primaquine (PQ) with the nano-hydrophobic cavity of beta-cyclodextrin (β-CD) was prepared by physical mixing, kneading and co-precipitation methods. (deepdyve.com)
  • The beta-cyclodextrin form has the broadest applicability. (sigmaaldrich.com)
  • PDF] Correlation of polymer-like solution behaviors with electrospun fiber formation of hydroxypropyl-β-cyclodextrin and the adsorption study on the fiber. (semanticscholar.org)
  • The good news is that researchers have identified a unique fiber called alpha-cyclodextrin that significantly reduces deadly glucose surges. (thefreelibrary.com)
  • FBCx is alpha-cyclodextrin, which is a type of fiber produced from corn. (evitamins.com)
  • Absorption, distribution, and excretion -cyclodextrin is resistant to hydrolysis by acid (Szeftli & Budai, 1976), alpha- and -amylases and yeast. (inchem.org)
  • 1985). The intestinal absorption, digestibility by the colonic microflora, and urinary excretion of -cyclodextrin were studied. (inchem.org)
  • Cyclodextrins can considerably enhance the body's absorption of non-bioavailable active ingredients. (wacker.com)
  • In α-cyclodextrin, the six glucose subunits are linked end to end via α-1, 4 linkages. (wikipedia.org)
  • The exterior surface of cyclodextrins is somewhat hydrophilic whereas the interior core is hydrophobic. (wikipedia.org)
  • Supramolecular polymers with monomers bound together by secondary interactions, such as polyrotaxanes (PRXs), consisting of alpha cyclodextrin (αCD) threaded onto poly(ethylene glycol) (PEG), have attracted interest as a result of their ability to overcome physical limitations present in conventional, covalently structured polymers. (rsc.org)
  • The compositions can further comprise cyclodextrin-compatible and -incompatible materials, and other optional ingredients. (google.com.au)
  • We are China Origin Factory of Molecular Weight of Alpha Cyclodextrin. (zycydextrin.com)
  • MUNICH, GERMANY - Alpha-cyclodextrins from Wacker, marketed under the Cavamax W6 brand, may enhance the foaming properties of milk in specialty coffees. (foodbusinessnews.net)
  • Highlights include CAVAMAX ® cyclodextrin, CAVACURMIN ® , a gammadextrin-curcumin complex, vegetarian L-Cysteine and HTEssence ® , a nature identical hydroxytyrosol that significantly reduces low density lipoprotein (LDL) cholesterol. (wacker.com)
  • As one of professional alpha cyclodextrin manufacturers and suppliers in China, we'll provide you with the best alpha cyclodextrin made in China. (cyclodextrinchina.com)
  • the Primaquine molecule is deeply entrapped in the cavity of β-cyclodextrin, which was confirmed by analysis of spectral shifts and corresponding absorbance and fluorescence intensities. (deepdyve.com)
  • Rasheed, A.: Cyclodextrins as drug carrier molecule: a review. (springer.com)
  • These structures give evidence for substrate distortion and the covalent character of the intermediate and for the first time show, in atomic detail, how catalysis in the alpha-amylase family proceeds by the concerted action of all active site residues. (ubc.ca)
  • Wenz, G.: Cyclodextrins as building blocks for supramolecular structures and functional units. (springer.com)
  • Alpha-cyclodextrin is widely used in the drugs, food, flavor and cosmetics. (zycydextrin.com)