OrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and Occupations
Cyclodextrinsalpha-Cyclodextrinsbeta-Cyclodextrinsgamma-CyclodextrinsDextrinsTrimeprazineRotaxanesSolubilityStarchChemistry, PharmaceuticalMicromonosporaceaeOptical RotationSun Protection Factoralpha-AmylasesMyristatesGlucan 1,4-alpha-GlucosidaseDrug StabilityGlucosyltransferasesAcarboseDrug CarriersGlycoside HydrolasesSolutionsalpha 1-AntitrypsinHydrophobic and Hydrophilic InteractionsDrug CompoundingSpectrometry, Mass, Fast Atom BombardmentCalorimetry, Differential ScanningMagnetic Resonance SpectroscopyModels, MolecularKineticsBacillus
Cyclodextrins
A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.
alpha-Cyclodextrins
Cyclic GLUCANS consisting of six (6) glucopyranose units linked by 1,4-glycosidic bonds.
beta-Cyclodextrins
Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.
gamma-Cyclodextrins
Cyclic GLUCANS consisting of eight (8) glucopyranose units linked by 1,4-glycosidic bonds.
Dextrins
Trimeprazine
A phenothiazine derivative that is used as an antipruritic.
Rotaxanes
Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS.
Solubility
The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Starch
Any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. It is the chief storage form of energy reserve (carbohydrates) in plants.
Chemistry, Pharmaceutical
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
Micromonosporaceae
A family of gram-positive, saprophytic bacteria occurring in soil and aquatic environments.
Optical Rotation
The rotation of linearly polarized light as it passes through various media.
Sun Protection Factor
A measure of relative protection provided by SUNSCREENING AGENTS against burns due to ultraviolet (UV) radiation from a light source.
alpha-Amylases
Enzymes that catalyze the endohydrolysis of 1,4-alpha-glycosidic linkages in STARCH; GLYCOGEN; and related POLYSACCHARIDES and OLIGOSACCHARIDES containing 3 or more 1,4-alpha-linked D-glucose units.
Myristates
Salts and esters of the 14-carbon saturated monocarboxylic acid--myristic acid.
Glucan 1,4-alpha-Glucosidase
An enzyme that catalyzes the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of polysaccharide chains with the release of beta-glucose. It is also able to hydrolyze 1,6-alpha-glucosidic bonds when the next bond in sequence is 1,4.
Drug Stability
The chemical and physical integrity of a pharmaceutical product.
Glucosyltransferases
Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor molecule which is frequently another carbohydrate. EC 2.4.1.-.
Acarbose
An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE.
Drug Carriers
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Glycoside Hydrolases
Solutions
The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)
alpha 1-Antitrypsin
Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.
Hydrophobic and Hydrophilic Interactions
The thermodynamic interaction between a substance and WATER.
Drug Compounding
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
Spectrometry, Mass, Fast Atom Bombardment
A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.
Calorimetry, Differential Scanning
Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.
Magnetic Resonance Spectroscopy
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
Models, Molecular
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
Kinetics
The rate dynamics in chemical or physical systems.
Bacillus
A genus of BACILLACEAE that are spore-forming, rod-shaped cells. Most species are saprophytic soil forms with only a few species being pathogenic.

Properties of a cyclodextrin-specific, unusual porin from Klebsiella oxytoca. (1/76)

The function of CymA, 1 of the 10 gene products involved in cyclodextrin uptake and metabolism by Klebsiella oxytoca, was characterized. CymA is essential for growth on cyclodextrins, but it can also complement the deficiency of a lamB (maltoporin) mutant of Escherichia coli for growth on linear maltodextrins, indicating that both cyclic and linear oligosaccharides are accepted as substrates. CymA was overproduced in E. coli and purified to apparent homogeneity. CymA is a component of the outer membrane, is processed from a signal peptide-containing precursor, and possesses a high content of antiparallel beta-sheet. Incorporation of CymA into lipid bilayers and conductance measurements revealed that it forms ion-permeable channels, which exhibit a substantial current noise. CymA-induced membrane conductance decreased considerably upon addition of alpha-cyclodextrin. Titration experiments allowed the calculation of a half-saturation constant, K(S), of 28 microM for its binding to CymA. CymA assembled in vitro to two-dimensionally crystalline tubular membranes, which, on electron microscopy, are characterized by a p1-related two-sided plane group. The crystallographic unit cell contains four monomeric CymA molecules showing a central pore. The lattice parameters are a = 16.1 nm, b = 3.8 nm, gamma = 93 degrees. CymA does not form trimeric complexes in lipid membranes and shows no tendency to trimerize in solution. CymA thus is an atypical porin with novel properties specialized to transfer cyclodextrins across the outer membrane.  (+info)

Enzymatic synthesis of N-acetylglucosaminyl-cyclodextrin by the reverse reaction of N-acetylhexosaminidase from jack bean. (2/76)

Novel heterobranched cyclodextrins (CDs), N-acetylglucosaminyl-cyclodextrins (GlcNAc-CD), were synthesized from a mixture of GlcNAc and alpha, beta, or gamma CD by the reverse reaction of N-acetylhexosaminidase from jack bean. Optimum pH and temperature for the production of GlcNAc-alpha CD by N-acetylhexosaminidase were pH 4.9 and 50-70 degrees C, respectively. The maximum yield of GlcNAc-alpha CD was 17.5% (mol/mol) at the concentration of 1 M GlcNAc and 0.25 M alpha CD. The reverse reaction product, GlcNAc-alpha CD, was separated into two peaks by HPLC analysis on the ODS column. Their structures were identified as 6-O-beta-D-N-acetylglucosaminyl-alpha CD and 2-O-beta-D-N-acetylglucosaminyl-alpha CD by FAB-MS and NMR spectroscopies. N-Acetylhexosaminidase from jack bean also synthesized N-acetylgalactosaminyl-alpha CD from N-acetylgalactosamine and alpha CD.  (+info)

Probing protein-sugar interactions. (3/76)

We have investigated the partial specific volumes (2) (ml/g), hydration, and cosolvent interactions of rabbit muscle aldolase by equilibrium sedimentation in the analytical ultracentrifuge and by direct density increment (partial differential/partial differentialc(2))(mu) measurements over a range of sugar concentrations and temperature. In a series of sugars increasing in size, glucose, sucrose, raffinose, and alpha-cyclodextrin, (partial differential/ partial differentialc(2))(mu) decreases linearly with the solvent density rho(0). These sugar cosolvents do not interact with the protein; however, the interaction parameter B(1) (g water/g protein) mildly increases with increasing sugar size. The experimental B(1) values are smaller than values calculated by excluded volume (rolling ball) considerations. B(1) relates to hydration in this and in other instances studied. It decreases with increasing temperature, leading to an increase in (2) due to reduced water of hydration electrostriction. The density increments (partial differential/ partial differentialc(2))(mu), however, decrease in concave up form in the case of glycerol and in concave down form for trehalose, leading to more complex behavior in the case of carbohydrates playing a biological role as osmolytes and antifreeze agents. A critical discussion, based on the thermodynamics of multicomponent solutions, is presented.  (+info)

alpha-cyclodextrin extracts diacylglycerol from insect high density lipoproteins. (4/76)

alpha-Cyclodextrins are water-soluble cyclic hexamers of glucose units with hydrophobic cavities capable of solubilizing lipophiles. Incubating alpha-cyclodextrin with high density lipophorin from Manduca sexta or Bombyx mori resulted in a cloudy, turbid solution. Centrifugation separated a pale yellowish precipitate. Thin-layer chromatography analysis of the lipid extract of the precipitate showed that the major lipid was diacylglycerol, while KBr density gradient analysis of the supernatant demonstrated the presence of a lipid-depleted very high density lipophorin. Transfer of diacylglycerol from lipophorin to cyclodextrin was specific to alpha-cyclodextrin and was not observed with beta- or gamma-cyclodextrins. pH had no effect on diacylglycerol transfer to alpha-cyclodextrin. However, the transfer was strongly dependent on the concentration of alpha-cyclodextrin and temperature. Increasing the concentration of alpha-cyclodextrin in the incubation mixture was associated with the formation of increasingly higher density lipophorins. Thus, at 20, 30, and 40 mm alpha-cyclodextrin, the density of B. mori lipophorin increased from 1.107 g/ml to 1.123, 1. 148, and 1.181 g/ml, respectively. At concentrations greater than 40 mm, alpha-cyclodextrin had no further effect on the density of lipophorin. alpha-Cyclodextrin removed at most 83;-87% of the diacylglycerol present in lipophorin. Temperature played an important role in altering the amount of diacylglycerols transferred to alpha-cyclodextrin. At 30 mm alpha-cyclodextrin, the amount of diacylglycerol transferred at different temperatures was 50% at 4 degrees C, 41% at 15 degrees C, 20% at 28 degrees C, and less than 3% at 37 degrees C. We propose that diacylglycerol transfers to alpha-cyclodextrin via an aqueous diffusion pathway and that the driving force for the transfer is the formation of an insoluble alpha-cyclodextrin-diacylglycerol complex.  (+info)

Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying. (5/76)

The taste and flavor of spray-dried powdered products are the most important quality factors. In the present study, molecular encapsulation in cyclodextrin was applied to prevent the loss of a hydrophobic flavor compound (l-menthol) during the drying of a droplet. beta-Cyclodextrin appeared to be a better encapsulant for menthol than alpha- and gamma-cyclodextrin. The retention of menthol increased with increasing concentration of both cyclodextrin and maltodextrin. A simple mathematical model is proposed for estimating the flavor retention. The theoretical results by this model estimated well the final retention of menthol encapsulated in a blend of beta-cyclodextrin and maltodextrin.  (+info)

Mechanism of porcine pancreatic alpha-amylase. Inhibition of amylose and maltopentaose hydrolysis by alpha-, beta- and gamma-cyclodextrins. (6/76)

The effects of alpha-, beta- and gamma-cyclodextrins on the amylose and maltopentaose hydrolysis catalysed by porcine pancreatic alpha-amylase (PPA) were investigated. The results of the statistical analysis performed on the kinetic data using the general initial velocity equation of a one-substrate reaction in the presence of one inhibitor indicate that the type of inhibition involved depends on the substrate used: the inhibition of amylose hydrolysis by alpha-, beta- and gamma-cyclodextrin is of the competitive type, while the inhibition of maltopentaose hydrolysis is of the mixed noncompetitive type. Consistently, the Lineweaver-Burk plots intersect on the vertical axis when amylose is used as the substrate, while in the case of maltopentaose, the intersection occurs at a point located in the second quadrant. The inhibition of the hydrolysis therefore involves only one abortive complex, PPA-cyclodextrin, when amylose is used as the substrate, while two abortive complexes, PPA-cyclodextrin and PPA-maltopentaose-cyclodextrin, are involved with maltopentaose. The mixed noncompetitive inhibition thus shows the existence of one accessory binding site. In any case, only one molecule of inhibitor binds to PPA. In line with these findings, the difference spectra of PPA produced by alpha-, beta- and gamma-cyclodextrin indicate that binding occurs at a tryptophan and a tyrosine residue. The corresponding dissociation constants and the inhibition constants obtained using the kinetic approach are in the same range (1.2-7 mM). The results obtained here on the inhibition of maltopentaose hydrolysis by cyclodextrin are similar to those previously obtained with acarbose as the inhibitor [Alkazaz, M., Desseaux, V., Marchis-Mouren, G., Prodanov, E. & Santimone, M. (1998) Eur. J. Biochem. 252, 100-107], but differ from those obtained with amylose as the substrate and acarbose as inhibitor [Alkazaz, M., Desseaux, V., Marchis-Mouren, G., Payan, F., Forest, E. & Santimone, M. (1996) Eur. J. Biochem. 241, 787-796]. It is concluded that the hydrolysis of both long and short chain substrates requires at least one secondary binding site, including a tryptophan residue.  (+info)

Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media. (7/76)

Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with a- and /-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-beta-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 x 10(5) mol(-2) l(2) was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.  (+info)

Pharmacokinetics and pharmacodynamics of human chorionic gonadotropin (hCG) after rectal administration of hollow-type suppositories containing hCG. (8/76)

To determine the effectiveness of human chorionic gonadotropin (hCG) administered rectally, we studied the pharmacokinetics and pharmacodynamics of hCG using a hollow-type suppository. HCG was not detected in plasma when only hCG was administered rectally, even at a higher dose (4,000 IU/kg body weight) than intravenous injection, because of its low bioavailability due to high molecular weight or degradation by proteolytic activity. To enhance the rectal absorption of hCG, the effectiveness of its coadministration with alpha-cyclodextrin (alpha-CyD), an absorption-enhancing agent, was investigated in male rabbits. HCG was detected in plasma following coadministration of hCG and alpha-CyD (10 mg/kg body weight) into the rectum. The plasma hCG concentration increased with increasing dose of alpha-CyD. The AUC(0-48) observed after coadministration of hCG and alpha-CyD at 30 mg/kg body weight was approximately four times higher than that of hCG and alpha-CyD at 10mg/kg body weight. HCG at a high concentration induced a rapid increase in the plasma testosterone concentration (74.2 +/- 3.4 ng/ml) 2 h after intravenous administration. However, the testosterone concentration 24 h after intravenous administration decreased to the physiological level (approximately 20 ng/ml) which had been observed before such administration. On the other hand, the maximum level of testosterone concentration (40.0 +/- 12.6 ng/ml) was observed 24 h after rectal administration of hCG (400 IU/kg body weight) in combination with alpha-CyD (30 mg/kg body weight). Moreover, the plasma testosterone concentration (31.0 +/- 11.4 ng/ml) obtained 72 h after rectal administration tended to be maintained at a higher level than that (14.4 +/- 0.9ng/ml) observed before the administration. These results suggest that the hollow-type suppository as a rectal delivery system of hCG is promising as a new mode of hCG therapy.  (+info)

Alpha-Cyclodextrin - WikipediaAlpha-Cyclodextrin - Wikipedia
alpha-Cyclodextrin (α-dextrin, α-cyclodextrin, α-CD, alphadextrin, alpha cyclodextrin (dietary fiber)) is a polysaccharide of six glucose units that are covalently attached end to end via α-1, 4 linkages. This fiber is sold under the brand names, Alpha-Fibe and Calorease. Alpha-Fibe is the original product that contains this unique fiber, introduced to the worldwide nutritional supplement market by Bio-Form Essentials in 2007. Soho Flordis International became the patent Assignee as of March 30, 2012 and launched the brand Calorease in 2013. FBCx is not an ingredient, only an abbreviation, and is not part of the scientific name. The abbreviation FBCx, stands for Fat Binding Complexer and can be associated with the brand names, Alpha-Fibe and Calorease. There are two other naturally occurring cyclodextrins, β (beta) - and γ (gamma) -, which contain seven and eight glucose units respectively. In water, these fibers take on a toroid or truncated cone configuration. In aqueous ...
https://en.wikipedia.org/wiki/Alpha-Cyclodextrin
Determinants of the hyperdynamic circulation and central hypovolaemia in cirrhosis - Danish National Research Database-Den...Determinants of the hyperdynamic circulation and central hypovolaemia in cirrhosis - Danish National Research Database-Den...
Patients with advanced cirrhosis often develop a hyperdynamic circulation with central hypovolaemia. The events that initiate the systemic haemodynamic abnormalities and the coupling of these factors to splanchnic haemodynamics are still unclear. Objective On the basis of a large population of patients with cirrhosis to identify splanchnic and clinical characteristics associated with the development of the hyperdynamic circulation and survival ...
http://www.forskningsdatabasen.dk/catalog/248455464
RCSB PDB - 3L2M: X-ray Crystallographic Analysis of Pig Pancreatic Alpha-Amylase with Alpha-cyclodextrin Structure...RCSB PDB - 3L2M: X-ray Crystallographic Analysis of Pig Pancreatic Alpha-Amylase with Alpha-cyclodextrin Structure...
3L2M: X-ray crystallographic analyses of pig pancreatic alpha-amylase with limit dextrin, oligosaccharide, and alpha-cyclodextrin.
http://www.rcsb.org/pdb/explore.do?structureId=3l2m
Astec® CHIRALDEX A-TA - Capillary GC Columns, by name | Sigma-AldrichAstec® CHIRALDEX A-TA - Capillary GC Columns, by name | Sigma-Aldrich
Incorporates a phase consisting of a 2,6-di-O-pentyl-3-trifluoroacetyl derivative of alpha-cyclodextrin. Exhibits high selectivity for oxygen containing analytes in the form of alcohols, ketones, acids, aldehydes, and lactones. Highly selective for halogenated compounds.
http://www.sigmaaldrich.com/analytical-chromatography/analytical-products.html?TablePage=17923664
Cyanide and Happiness by on PreziCyanide and Happiness by on Prezi
A chain superstructure is formed (bundles of needles) is formed during rapid co-precipitation of alpha-cyclodextrin (cyclic starch w/ glucose) and KAuBr4 in ...
https://prezi.com/ler_qjnyqblh/cyanide-and-happiness/
Evgen Pharma has first European patent grantedEvgen Pharma has first European patent granted
SFX-01 is a synthetic version of the naturally occurring compound sulforaphane, which has been stabilised in an alpha-cyclodextrin lattice. Evgen Pharma is currently conducting two Phase II trials of SFX-01, one in advanced breast cancer and one in a type of stroke called subarachnoid haemorrhage.. The patent granted today, which covers the manufacturing and scale-up of SFX-01, marks the first patent to be granted for SFX-01 in Europe, where a composition of matter patent is also pending. Todays patent grant marks the Companys eighth patent to be granted this year, reflecting the growth in the Companys patent estate.. The European patent, numbered EP2854861 and entitled Method of Synthesising Sulforaphane, can be viewed at this link: https://register.epo.org/application?number=EP13726846&tab=doclist. The patent runs until May 2033.. This core manufacturing patent has already been granted in the United States, Australia and Japan and is pending in other countries worldwide.. Evgen Pharma holds ...
http://www.imprimaturcapital.com/news/evgen-pharma-has-first-european-patent-granted/
Molecular Recognition of Anions by Zwitterionic Host Molecules in Water.Molecular Recognition of Anions by Zwitterionic Host Molecules in Water.
COMMUNICATIONS (C;imhridge Skieoscm 250 M3). The density of the synthesized material ({I = 2.47 gcni I ) was determined with the suspension method using butyl acetate and broinoforni as suspension liquids N M R experiments were carried out on a Bruker ASX 400 spectrometer at 79.495 MHz for Si. Received: July 2. 1994 [Z7092IE] German version: Arrgm.. C,iwi. 1995. 107. 12.5 - Keywords: silicon compounds structure elucidation zeolites zinc compounds bonds results in the specific and enthalpicallq strong binding of the anionic guest ion.[5.61 In order to mimic this natural binding principle we designed the artificial hosts 1 and 2. By virtue of the electrostatic repulsion of the inner cationic centers these molecules are inclined to adopt inflated conformations with cavities which may encapsu- - 111 J. V Smith. ~ / 7 ~ 1 ? 7Reij. . 1988. 8. 149. (21 (3 0. Brunner. W. M. Meier. Nurure 1989. 337, 146. [3] S . Merlino. tur. J Minrrul. 1990. 2,809. [4] M. J. Anncn. M . E. Davis. J. B. Higgins. J. L. ...
https://www.docme.ru/doc/1948639/molecular-recognition-of-anions-by-zwitterionic-host-mole..
Intercalation (chemistry) - WikipediaIntercalation (chemistry) - Wikipedia
In biochemistry, intercalation is the insertion of molecules between the bases of DNA. This process is used as a method for analyzing DNA and it is also the basis of certain kinds of poisoning. Clathrates are chemical substances consisting of a lattice that traps or contains molecules. Usually, clathrate compounds are polymeric and completely envelop the guest molecule. Inclusion compounds are often molecules, whereas clathrates are typically polymeric. Intercalation compounds are not 3-dimensional, unlike clathrate compounds.[6] According to IUPAC, clathrates are Inclusion compounds in which the guest molecule is in a cage formed by the host molecule or by a lattice of host molecules.[7] ...
https://en.wikipedia.org/wiki/Exfoliation_corrosion
Crystals | Free Full-Text | Determination of the Absolute Configuration of Aegelinol by Crystallization of Its Inclusion...Crystals | Free Full-Text | Determination of the Absolute Configuration of Aegelinol by Crystallization of Its Inclusion...
The absolute configuration and structure of aegelinol, a pyranocoumarin isolated from Ferulago asparagifolia Boiss (Apiaceae), has been determined by crystallography. Crystal structure of the inclusion complex of aegelinol in β-cyclodextrin was determined (a = 15.404(1) Å, b = 15.281(1) Å, c = 17.890(1) Å, α = 99.662(1), β = 113.4230(1), γ = 102.481(1)°, P1; R1 = 6.71%) and allowed unambiguous determination of the absolute configuration of the stereogenic center of aegelinol. The pyranocoumarin guest is included within the cylindrical cavity formed by dimeric β-cyclodextrin molecules with a head-to-head arrangement. Crystal structure of aegelinol alone was also determined (a = 6.8921(3) Å, b = 11.4302(9) Å, c = 44.964(3) Å, P212121; R1 = 4.44%) and allowed precise determination of its geometry. Aegelinol crystallizes with three molecules in the asymmetric unit held together by H-bonds and π-stacking interactions.
http://www.mdpi.com/2073-4352/2/4/1441/htm
Crystals | Free Full-Text | Determination of the Absolute Configuration of Aegelinol by Crystallization of Its Inclusion...Crystals | Free Full-Text | Determination of the Absolute Configuration of Aegelinol by Crystallization of Its Inclusion...
The absolute configuration and structure of aegelinol, a pyranocoumarin isolated from Ferulago asparagifolia Boiss (Apiaceae), has been determined by crystallography. Crystal structure of the inclusion complex of aegelinol in β-cyclodextrin was determined (a = 15.404(1) Å, b = 15.281(1) Å, c = 17.890(1) Å, α = 99.662(1), β = 113.4230(1), γ = 102.481(1)°, P1; R1 = 6.71%) and allowed unambiguous determination of the absolute configuration of the stereogenic center of aegelinol. The pyranocoumarin guest is included within the cylindrical cavity formed by dimeric β-cyclodextrin molecules with a head-to-head arrangement. Crystal structure of aegelinol alone was also determined (a = 6.8921(3) Å, b = 11.4302(9) Å, c = 44.964(3) Å, P212121; R1 = 4.44%) and allowed precise determination of its geometry. Aegelinol crystallizes with three molecules in the asymmetric unit held together by H-bonds and π-stacking interactions.
http://www.mdpi.com/2073-4352/2/4/1441
Kemps triacid attached to octa-O-methyl resorc[4]arenes: conformations in solution and comparative binding studies with...
We synthesized the new supramolecular host molecules 7 and 13 based on functionalized resorcarenes bearing Kemps triacid. Conformations in solution have been investigated and the influence of intra-and intermolecular hydrogen bonds from the triacid was shown by low temperature and DOSY NMR experiments. The results of host 7 are supported by DFT calculations. The binding behaviour of 7 towards different 2-amino pyridincs in chloroform has been investigated by NMR titrations. The association constants reach from K 207 M-1 for 2-amino-5-cyano pyridine to K=1551 M-1 for 2-amino-4-methyl pyridine. The association constants of the formed complexes of 7 with 2-amino pyridines were compared with those of the simple host systems 14 and 15 in order to evaluate the influence of the attached resorcarene host. (c) 2008 Elsevier Ltd. All rights reserved ...
https://pub.uni-bielefeld.de/publication/1588385
In Silico Comparison of Separate or Combinatorial Effects of Po-tential Inhibitors of the SARS-CoV-2 Binding Site of ACE2 ...In Silico Comparison of Separate or Combinatorial Effects of Po-tential Inhibitors of the SARS-CoV-2 Binding Site of ACE2 ...
Background: The COVID-19 is a pandemic viral infection with a high morbidity rate, leading to many worldwide deaths since the end of 2019. The RBD (Receptor Binding Domain) of SARS-CoV-2 through its spike utilizes several host molecules to enter host cells. One of the most important ones is the angiotensin-converting enzyme 2 (ACE2), an enzyme normally engaged in renin angiotensin pathway and is responsible for hypertension regulation. As different articles have analyzed separate compounds which can bind ACE2 as the potential virus entry blockers, and each one with a different molecular docking algorithm, in this study we compared all candidate compounds individually as well as their combinations using a unique validated software to introduce most promising ones.. Methods: We collected and prepared a list of all available compounds which potentially can inhibit RBD binding site of the ACE2 from different studies and then reanalyzed and compared them using the Patchdock (ver. 1.3) as a suitable ...
https://ijph.tums.ac.ir/index.php/ijph/article/view/23398
Diverse evolutionary patterns of pneumococcal antigens identified by pangenome-wide immunological screening | PNASDiverse evolutionary patterns of pneumococcal antigens identified by pangenome-wide immunological screening | PNAS
Combining population genomic data with clinical information on the human IgG response to pneumococcal proteins provides a unique insight into the complex immunological interaction between host and pathogen. The continuous distribution of IgG binding values suggests that adaptive immunity responds to many antigens in both the core and the accessory genome. The most immunogenic proteins had physical properties expected to be associated with antibody binding: signal peptides, including those with a YSIRK motif, for secretion out of the bacterial cell; large size; and a lipoprotein processing motif, LPXTG sortase processing motif or CBD for surface attachment. The great majority of the ABTs either were variants of the diverse PspA, PspC, ZmpA, and ZmpB proteins or could be grouped into surface-exposed roles in host molecule adhesion or degradation, cell wall metabolism, or solute binding for transport. Despite the proteins on the microarray being expressed in vitro, detected ABTs included examples ...
https://www.pnas.org/content/114/3/E357
Training CoursesTraining Courses
INTRODUCTION. Structure-based drug design seeks to identify and optimize specific attractive interactions between two partner molecules in biological systems between ligands and their host molecules, typically proteins. The simple answer to whats holding the industry back in terms of adoption of latest drug discovery techniques is Education. There simply arent enough individuals trained on the use of Proteomics, Virtual Screening, Molecular Docking, Simulations, Dynamics and ADMET- multidisciplinary approaches, which is why we continue to offer courses, for both novice and experienced users, on the use of this technology as it applies to their research functions.. This 1 day training course will focus on the use of efficient technologies used in the discovery & designing of Drugs on the basis of the biological targets critical to the disease condition.. During this course, you will be introduced to basic principles of Rational Drug Design along with Proteomics in Drug Discovery. The course ...
https://selectbiosciences.com/trainingCoursesID.aspx?tc=DDD16&pid=4820&conf=DDI16
Plus itPlus it
These data show that there is an increasing potency of then-alkanol series for stabilizing BSA, but that the low aqueous solubility of the members longer than C10 limit the occupancy of n-alkanol binding sites, despite progressively increasing binding constants. For a soluble protein that does not significantly bind the alcohols studied, i.e., myoglobin, a progressive increase in potency for destabilization was observed until, again, a water solubility-limited cutoff effect occurred at about C10. Taken together, these results strongly suggest that solubility issues dominate then-alkanol cutoff effect. This is consistent with the observed shift in cutoff point in other homologous series. For example, relative to the C13-14 in vivo cutoff point for the saturatedn-alkanols, the less soluble n-alkane series have a shorter cutoff point (C10; Miller and Alifimoff, 1998), and the more soluble unsaturated n-alkanol series have a longer cutoff point (C15; Pringle et al., 1981). Also, similar in vivo ...
http://molpharm.aspetjournals.org/content/56/2/414
Sequence Similarity - 1OT1: Bacillus circulans strain 251 Cyclodextrin glycosyl transferase mutant D135A Sequence...Sequence Similarity - 1OT1: Bacillus circulans strain 251 Cyclodextrin glycosyl transferase mutant D135A Sequence...
1OT1: The fully conserved Asp residue in Conserved sequence region I of the alpha-amylase Family is crucial for the Catalytic Site Architecture and Activity
http://www.rcsb.org/pdb/explore/sequenceCluster.do?structureId=1OT1
Capillary Chromatography - Applications of Capillary Columns in GC Analysis 3 :: Chromatography OnlineCapillary Chromatography - Applications of Capillary Columns in GC Analysis 3 :: Chromatography Online
The arrangement of the glucose units in the three different forms of cyclodextrin are shown in figure 26. The mouth of the torus-shaped cyclodextrin molecule has a larger circumference than at the base and is linked to secondary hydroxyl groups of the C2 and C3 atoms of each glucose unit (see figure 27). The primary hydroxyl groups are located at the base of the torus on the C6 atoms. As these hydroxyl groups are free to rotate, they partially block the base aperture. The size of the cavity increases with increasing number of glucose units (figure 26).The secondary hydroxyl groups can be reacted with appropriate reagents to introduce additional and different interactive character to the cyclodextrin molecule. The strong chiral selectivity of the cyclodextrins structures is thought to arise from the many chiral centers they contain (e.g., b-cyclodextrin has 35 stereogenic centers). The cyclodextrins are probably the most effective chirally selective stationary phases presently available for the ...
http://chromatography-online.org/Applications/Chiral-Separations/rs_12_39.php
Cyclodextrins | China-Mainland | Sigma-AldrichCyclodextrins | China-Mainland | Sigma-Aldrich
The solubility of natural cyclodextrins is very poor and initially this prevented cyclodextrins from becoming effective complexing agents. In the late 1960s, it was discovered that chemical substitutions at the 2-, 3-, and 6-hydroxyl sites would greatly increase solubility. The degree of chemical substitution and the nature of the groups used for substitution determine the final maximum concentration of cyclodextrin in an aqueous medium. Most chemically modified cyclodextrins are able to achieve a 50% (w/v) concentration in water.. Cavity size is the major determinant as to which cyclodextrin is used in complexation. Fit is critical to achieving good incorporation of cyclodextrins. α-Cyclodextrins have small cavities that are not capable of accepting many molecules. γ-Cyclodextrins have much larger cavities than many molecules to be incorporated, and cyclodextrin hydrophobic charges cannot effectively interact to facilitate complexation. The cavity diameter of β-cyclodextrins has been ...
https://www.sigmaaldrich.com/china-mainland/zh/technical-documents/articles/biofiles/cyclodextrins.html
Moonlighting of Helicobacter pylori catalase protects against complement-mediated killing by utilising the host molecule...Moonlighting of Helicobacter pylori catalase protects against complement-mediated killing by utilising the host molecule...
article{7ad5f90a-94c1-4c5e-b086-8e73a88d96b6, abstract = {,p,Helicobacter pylori is an important human pathogen and a common cause of peptic ulcers and gastric cancer. Despite H. pylori provoking strong innate and adaptive immune responses, the bacterium is able to successfully establish long-term infections. Vitronectin (Vn), a component of both the extracellular matrix and plasma, is involved in many physiological processes, including regulation of the complement system. The aim of this study was to define a receptor in H. pylori that binds Vn and determine the significance of the interaction for virulence. Surprisingly, by using proteomics, we found that the hydrogen peroxide-neutralizing enzyme catalase KatA is a major Vn-binding protein. Deletion of the katA gene in three different strains resulted in impaired binding of Vn. Recombinant KatA was generated and shown to bind with high affinity to a region between heparin-binding domain 2 and 3 of Vn that differs from previously characterised ...
https://lup.lub.lu.se/search/publication/7ad5f90a-94c1-4c5e-b086-8e73a88d96b6
Daily Online News: 2014Daily Online News: 2014
Have you wondered whether Febreze actually removes odors or whether it just covers them with a perfume? Have you wondered how it works? Heres the lowdown on Febreze. Its a product that was invented by Procter & Gamble and introduced in 1996. The active ingredient in Febreze is beta-cyclodextrin, a carbohydrate. Beta-cyclodextrin is an 8-sugar ringed molecule that is formed via an enzymatic conversion of starch. The cyclodextrin molecule sort of resembles a donut. When you spray Febreze, the water in the product partially dissolves the odor, allowing it to form a complex inside the hole of the cyclodextrin donut shape. The stink molecule is still there, but it cant bind to your odor receptors, so you cant smell it. Depending on the type of Febreze youre using, the odor might simply be deactivated or it might be replaced with something nice-smelling, like a fruity or floral fragrance. As Febreze dries, more and more of the odor molecules bind to the cyclodextrin, lowering the concentration ...
https://mr-chemist.blogspot.com/2014/
KAIST, Electrochemistry
The synthesis and structural analysis of two novel families of three-component reversible redox cycles [(C2B9H11)M(m-SPh)2]2nPPNn (M = Mo, n = 2-, 2; 1-, 3; 0, 4; and M = W, n = 2-, 6; 1-, 7; 0, 8), where the cleavage and re-formation of the carborane cage C-C bond is observed during the redox reaction, are reported. Electronic saturation of the metal center (18e center) and the lack of bulky substituents on the carborane cage suggest that the deformed carborane cages in 2·PPN2, 6·PPN2, and 7·PPN invoke a new kind of deformed cage (semicloso framework). The XPS results show that the unprecedented competition for electron density between the metal center and the carborane cage is involved in the cleavage and formation of the carborane C-C bond. ...
http://elchem.kaist.ac.kr/publication/paper/htm/2001_07_JACS.htm
Remediated Sequence - 3BMV: Cyclodextrin glycosyl transferase from Thermoanerobacterium thermosulfurigenes EM1 mutant...Remediated Sequence - 3BMV: Cyclodextrin glycosyl transferase from Thermoanerobacterium thermosulfurigenes EM1 mutant...
3BMV: Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution.
https://www3.rcsb.org/pdb/explore/remediatedSequence.do?params.showJmol=false&structureId=3BMV
Most recent papers with the keyword Foreskin | Read by QxMDMost recent papers with the keyword Foreskin | Read by QxMD
Polyelectrolyte multilayers assembled from hyaluronic acid (HA) and poly-l-lysine (PLL) are most widely studied showing excellent reservoir characteristics to host molecules of diverse nature; however, thick (HA/PLL)n films are often found cell repellent. By a systematic study of the adhesion and proliferation of various cells as a function of bilayer number n a correlation with the mechanical and chemical properties of films is developed. The following cell lines have been studied: mouse 3T3 and L929 fibroblasts, human foreskin primary fibroblasts VH-Fib, human embryonic kidney HEK-293, human bone cell line U-2-OS, Chinese hamster ovary CHO-K and mouse embryonic stem cells ...
https://www.readbyqxmd.com/keyword/120658
PDB 1cdg structure summary ‹ Protein Data Bank in Europe (PDBe) ‹ EMBL-EBIPDB 1cdg structure summary ‹ Protein Data Bank in Europe (PDBe) ‹ EMBL-EBI
1cdg: Nucleotide sequence and X-ray structure of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 in a maltose-dependent crystal form.
http://www.ebi.ac.uk/pdbe/entry/pdb/1cdg?view=true
Patent US5032182 - Branched cyclodextrins - Google PatentsPatent US5032182 - Branched cyclodextrins - Google Patents
Branched cyclodextrins are produced by the pyrolysis of cyclodextrins. The temperature range is 135 C. to 220 C. using equipment suitable for making British gum and other starch dextrins.
http://www.google.com/patents/US5032182?dq=6437692
Cellular delivery of polynucleotides by cationic cyclodextrin polyrotaxanes.Cellular delivery of polynucleotides by cationic cyclodextrin polyrotaxanes.
The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format. By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. To select a subset of the search results, click Selective Export button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export. After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format. ...
https://repository.helmholtz-hzi.de/handle/10033/266513
Histonet] Thanks & another question
Hi everyone.... Thanks to all of you who responded to my article request.......& heres another question Does anyone know of a staining method that would demonstrate the limit dextrin, after amylase digestion in FFPE tissue..... Thanks WAY in advance.... Good Weekend to all.... Luis _______________________________________________ Histonet mailing list [email protected] http://lists.utsouthwestern.edu/mailman/listinfo/histonet ...
http://www.histosearch.com/histonet/Mar04/HistonetThanksanotherques.html
Inactive beta-amylase elisa and antibodyInactive beta-amylase elisa and antibody
Shop Inactive beta-amylase ELISA Kit, Recombinant Protein and Inactive beta-amylase Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
https://www.mybiosource.com/protein_family.php?root=inactive-beta-amylase
Repositorio da Producao Cientifica e Intelectual da Unicamp: Production of branched cyclodextrins by reverse reaction of...Repositorio da Producao Cientifica e Intelectual da Unicamp: Production of branched cyclodextrins by reverse reaction of...
Formation of maltosyl cyclodextrins from mixtures of maltose and cyclodextrins by reverse reactions of Flavobacterium isoamylase and Klebsiella pullulanase was experimented and it was found that Klebsilla pullulanase produced 50.4 mg maltosyl alpha-cyclodextrin, 35.0 mg maltosyl beta-cyclodextrin and 55.4 mg maltosyl gamma-cyclodextrin per ml of reaction mixture, whereas Flavobacterium isoamylase did not form maltosyl cyclodextrins. Optimum conditions for formation of maltosyl beta-cyclodextrin by Klebsiella pullulanase were pH 4, 50 degrees C reaction temperature and proportion of substrate 100 mg beta-cyclodextrin/600 mg maltose per ml ...
http://repositorio.unicamp.br/jspui/handle/REPOSIP/70398
Carborane derivatives as inhibitors of human carbonic anhydrase isoenzymes | Institute of Molecular and Translational MedicineCarborane derivatives as inhibitors of human carbonic anhydrase isoenzymes | Institute of Molecular and Translational Medicine
Novelty, in brief, is represented by the intended elaboration of carborane, heteroborane and metallaborane compounds as active-site inhibitors of CA isoenzymes. All currently used inhibitors anhydrase inhibitors contain a sulfonamide or a sulfamate moiety connected to so called ring structure which is usually a 5- or 6-membered aromatic ring or conjugated ring system containing nitrogen, oxygen, and/or sulfur heteroatoms. The ring structure bears characteristics or functionality which modulates the affinity toward certain CA isoform. The use of three-dimensional boron cluster is a novel approach in development of isoform-specific CA inhibitors. Selected sulfamides incorporating cluster with inhibitory effects toward CAs (IC50 values in low micromolar and submicromolar range, some of the inhibitors being more than 50-times more selective toward the tumor specific CAIX than for CAII abundantly present in normal tissues ...
https://imtm.cz/carborane-derivatives-inhibitors-human-carbonic-anhydrase-isoenzymes-0
Blood testosterone levels are correlated with β-N-acetylhexosaminidase activity in human caput epididymis | IRIS Università...Blood testosterone levels are correlated with β-N-acetylhexosaminidase activity in human caput epididymis | IRIS Università...
β-N-acetylhexosaminidase exhibits a relatively high activity in human epididymis. Its isoenzymatic profile and immunological properties led us to conclude that the increased activity was not due to the expression of an isoform unrelated to the HEX A and B present in other human tissues. Measurement of enzyme levels in the three distinct epididymal regions revealed that in any given sample, activity was higher in the caput than in the corpus or cauda. Moreover, we found a striking correlation between β-HEX activity in the caput region and concentrations of blood testosterone, suggesting a possible involvement of the hormone in modulating enzyme expression. Since the caput epididymis plays a role in the maturation of sperm cells, our data may be an indication that β-HEX activity in the caput has a physiological relevance in human epididymis functions.. ...
https://research.unipg.it/handle/11391/122908
Treatment of Oil in Water Emulsions by Ceramic-Supported Polymeric Membranes
Treatment of Oil in Water Emulsions by Ceramic-Supported Polymeric Membranes. A novel membrane was developed by growing polymer chains from the surface of a porous ceramic support, resulting in a composite membrane which combines the mechanical properties of the inorganic membrane with the selective interactions of the polymer. The configuration of the grafted polymer brush layer is determined by solvent - polymer interactions, with a hydrophilic polymer being stretched away from the surface by aqueous solutions and collapsed against the surface by organic solvents. This behavior of the grafted chains provides Ceramic-Supported Polymeric (CSP) membranes with unique properties for certain water treatment applications. One application envisioned for these CSP membranes, in which the selectivity is influenced by interactions between the solvent and the grafted polymer, is the cross-flow filtration of an oil-in-water emulsion. In this case, a hydrophilic grafted polyvinylpyrrolidone (PVP) brush layer
http://cedb.asce.org/CEDBsearch/record.jsp?dockey=0089130
Einfluss von Cyclodextrinen auf die okulare Verfügbarkeit von Antiglaukomatosa und Immunsuppressiva in vitro / in vivoEinfluss von Cyclodextrinen auf die okulare Verfügbarkeit von Antiglaukomatosa und Immunsuppressiva in vitro / in vivo
In the past years, cyclodextrins (CDs) became more and more an important excipient for drug formulations. The main use of CDs in ophthalmic drug delivery is to increase the water solubility of lipophilic drugs, to modify drug bioavailability and to reduce ocular irritation. In the present study, the corneal permeability of different betablockers (in part combined with pilocarpine) in the presence of alpha-CD and hydroxypropylated (HP) alpha-, beta- and gamma-CD was examined. Addition of CDs often led to significant changes in permeation parameters, compared to CD-free solutions. The prodrug mycophenolate mofetil and its active drug mycophenolic acid (MPA) were solubilized by HP-beta-CD. The intraocular availability of these solutions was studied in the rabbit eye in vivo in comparison to a MMF-suspension. Applying MMF/HP-beta-CD-solution, the MPA level in cornea and aqueous humour (after 60 min) turned out to be significant higher than those of the MMF-suspension. In addition, for the extremely ...
https://edoc.hu-berlin.de/handle/18452/15799?C=N
Nanosized iron oxide particles entrapped in pseudo-single crystals gamma-cyclodextrin | IRIS Univ. CagliariNanosized iron oxide particles entrapped in pseudo-single crystals gamma-cyclodextrin | IRIS Univ. Cagliari
A new technique to produce very small magnetic nanoparticles of maghemite (gamma-Fe(2)O(3)) is presented. The particles form and precipitate in the presence of the oligosaccharide gamma-cyclodextrin and in the final product remain entrapped in tiny pseudo-single crystals of the organic host. Evidence of nanosized particles embedded in the organic crystal was obtained by HR-TEM studies that showed the occurrence of uniformly dispersed particles with average diameter of 18 Angstrom. The resulting objects gave diffraction patterns with the same spacing as that of cyclodextrin crystals without iron. The magnetic properties were investigated by ZFC-FC magnetizations, hysteresis loops, and ac susceptibility measurements. The compound presents a complex magnetic behavior that deviates from that predicted on the basis of the classic single domain particle model. The deviation is ascribed to the complex properties of the surface, which, for such small sizes, plays the major role in determining the total ...
https://iris.unica.it/handle/11584/32693
Photomodulated Supramolecular Chirality in Achiral Photoresponsive Rodlike Compounds Nanosegregated from the Helical...
TY - JOUR. T1 - Photomodulated Supramolecular Chirality in Achiral Photoresponsive Rodlike Compounds Nanosegregated from the Helical Nanofilaments of Achiral Bent-Core Molecules. AU - Kim, Kibeom. AU - Kim, Hanim. AU - Jo, Seong Yong. AU - Araoka, Fumito. AU - Yoon, Dong Ki. AU - Choi, Suk Won. PY - 2015/10/14. Y1 - 2015/10/14. N2 - We prepared a nonchiral mixture of achiral bent-core molecules and photoresponsive rodlike liquid crystalline (LC) molecules. With the help of the isothermal photochemical nematic (N)-isotropic (Iso) phase transition of the photoresponsive rodlike LC molecules, the corresponding phase transition from a dark conglomerate BX phase to another distinguishable dark conglomerate B4 phase took place in the mixture. A large circular dichroism (CD) signal originating from supramolecular chirality was detected in the initial BX phase. On the other hand, the detected CD signal was decreased in the B4 phase after UV irradiation. Interestingly, the decreased CD signal could be ...
https://minnesota-staging.pure.elsevier.com/en/publications/photomodulated-supramolecular-chirality-in-achiral-photoresponsiv
Interactions between cyclodextrins and cell-membrane phospholipids<...
TY - JOUR. T1 - Interactions between cyclodextrins and cell-membrane phospholipids. AU - Szejtli, J.. AU - Cserháti, T.. AU - Szögyi, M.. PY - 1986. Y1 - 1986. N2 - The interactions between cyclodextrins (CDs) and selected cell membrane phospholipids, liposomes and human erythrocytes were studied. Non-methylated cyclodextrins did not influence the differential scanning calorimetric behaviour of phospholipids and did not increase the permeability of dipalmitoyl-phosphatidyl-choline liposomes. Dimethyl- and trimethyl- β-CD interacted with the phospholipids but the effect was negligible compared to the effect of valinomycin. Reversed-phase thin-layer chromatography revealed complex formation with dimethyl-β-cyclodextrin, but not with others. The addition of cyclodextrins up to 10-2 mol litre-1 concentration did not modify the active or passive alkali ion transport of human erythrocytes, however, higher concentrations of added β-cyclodextrin especially dimethyl-β-cyclodextrin resulted in ...
https://hungary.pure.elsevier.com/en/publications/interactions-between-cyclodextrins-and-cell-membrane-phospholipid
Enzymes in the fermenter | BraukaiserEnzymes in the fermenter | Braukaiser
As expected the addition of enzymes boosted attenuation. Beano seems to digest more dextins than a malt extract. I wonder to what extent the difference is caused by limit dextrins (1-6 glucose links), which can only be broken by limit dextrinase, an enzyme which likely did not survive the 30 min mash at 60 C. Beanos glucoamylase is likely able to cleave both the 1-4 and the 1-6 links found in starch leaving only glucose and no limit dextrins.. It was surprising, however, that even with enzyme use during fermentation the apparent attenuation stayed in the mid 80s. This suggests that the low wort fermentability may not have been the result of incomplete starch and dextrin break-down during the mash. After all, I was going for very fermentable wort and held 30 min rests at 55 C, 63 C and 65 C followed by a 45 min rest at 72 C. I was expecting to get an attenuation limit in the high 80s with this mash schedule.. There was also a drop in pH. I contribute this to the extended fermentation activity, ...
http://braukaiser.com/blog/blog/2012/09/16/enzymes-in-the-fermenter/
Targeted drug delivery with modified gamma-Cyclodextrin nanocarriers and MR-guided focused ultrasound triggering | Journal of...Targeted drug delivery with modified gamma-Cyclodextrin nanocarriers and MR-guided focused ultrasound triggering | Journal of...
The desired gamma-CD based carrier greatly reduced DOXs toxicity in vitro: up to 95% toxicity reduction in KB human enpidermal carcinoma; up to 92% toxicity reduction in HCT116 colorectal carcinomar. Cellular DOX uptake was reduced 73% in muscle, 69% in kidney, 66% in liver, 65% in heart, 62% in brain, 53% in lungs as 25% in plasma in vivo. The carrier-DOX inclusion is highly stable under physiological temperature and pH as well as under a wide range of acidic conditions (pH 1.0~7.0); the encapsulated DOX is slowly released under hyperthermic conditions (up to 50°C). In the presence of MBs (0.1%, 1%, 2.5% and 5%) application of FUS with low mechanical indexes (0.24, 0.31 and 0.53), under which no thermal effect was observed, enhanced up to 3.89-fold of cellular drug uptake for encapsulated DOX in vitro. Optimal setup of MR parameters: TR/TE = 3180/96.3msec; bandwidth: 10.4 kHz; Field of View = 20×20cm; matrix: 384×384, NEX: 2; slice thickness: 2.0mm/1.0sp; number of slices: 8; frequency ...
https://jtultrasound.biomedcentral.com/articles/10.1186/2050-5736-3-S1-P79
Pound the alarm: danger signals in rheumatic diseases - ePrints - Newcastle UniversityPound the alarm: danger signals in rheumatic diseases - ePrints - Newcastle University
Damage-associated molecular patterns (DAMPs) are chemically heterogeneous endogenous host molecules rapidly released from damaged or dying cells that incite a sterile inflammatory response mediated via pattern recognition receptors (PRRs). The sources of DAMPs are dead or dying cells or the extracellular matrix and can signal through the PRRs, the Toll-like receptors or cytosolic Nod-like receptors, culminating in nuclear factor kappa B (NF-kappa B) activation and pro-inflammatory cytokine secretion. Together, these molecules are involved in sterile inflammation and many are associated with rheumatic autoimmune diseases such as rheumatoid arthritis, systemic lupus erythromatosus, psoriatic arthritis and systemic sclerosis. These diseases are associated with inflammation and many danger signals are found in sites of sterile inflammation and mediate inflammation. The present review examines the role of DAMPs in rheumatic conditions and suggests avenues for their therapeutic modulation.. ...
https://eprints.ncl.ac.uk/211334
US Patent # 4,797,214. Method of treatment of waste streams of oil/water emulsions or solutions - Patents.comUS Patent # 4,797,214. Method of treatment of waste streams of oil/water emulsions or solutions - Patents.com
A process for treating an emulsion or solution of water and oil or the like comprising the steps of (a) contacting said emulsion or solution with an inorganic salt; (b) contacting said emulsion or sol
http://www.patents.com/us-4797214.html
In situ control of cell adhesion using photoresponsive culture surface.<...
TY - JOUR. T1 - In situ control of cell adhesion using photoresponsive culture surface.. AU - Edahiro, Edahiro. AU - Junchi, Junchi. AU - Sumaru, Sumaru. AU - Kimio, Kimio. AU - Tada, Tada. AU - Yuichi, Yuichi. AU - Ohi, Ohi. AU - Katsuhide, Katsuhide. AU - Takagi, Takagi. AU - Toshiyuki, Toshiyuki. AU - Kameda, Kameda. AU - Mitsuyoshi, Mitsuyoshi. AU - Shinbo, Shinbo. AU - Toshio, Toshio. AU - Kanamori, Kanamori. AU - Yoshimi, Yoshimi. AU - Yasuo., Yasuo.. PY - 2005/2/16. Y1 - 2005/2/16. M3 - Article. VL - 6. SP - 970. EP - 974. JO - Biomacromolecules. JF - Biomacromolecules. SN - 1525-7797. ER - ...
https://shibaura.pure.elsevier.com/en/publications/in-situ-control-of-cell-adhesion-using-photoresponsive-culture-su-2
In situ control of cell adhesion using photoresponsive culture surface - Fingerprint - Shibaura Institute of Technology
Dive into the research topics of In situ control of cell adhesion using photoresponsive culture surface. Together they form a unique fingerprint. ...
https://shibaura.pure.elsevier.com/en/publications/in-situ-control-of-cell-adhesion-using-photoresponsive-culture-su/fingerprints/
Modification of photochemical reactivity by cyclodextrin complexation: alteration of photochemical behavior via restriction of...
The photochem. behavior of alkyldeoxybenzoins $PhCOCHPhCH_2CH_2R$ (R = H, Me, Et, hexyl, decyl) has been investigated in isotropic org. solvents, in aq. cyclodextrin solns., and bound to cyclodextrin in the solid state. Norrish type I and type II reactions occur in these media and the product distribution resulting from these primary processes are dependent on the medium. In org. solvents, type I and type II products are obtained in equal amts. In aq. cyclodextrin soln., type II products are formed in large excess. In the solid state, type II products constitute more than 90% of the product distribution. Ratios of products resulting from elimination and cyclization from the type II 1,4-diradical are also altered by the host cyclodextrin. Conformational and super-cage effects have been invoked to rationalize the dramatic alteration of the photobehavior of alkyldeoxybenzoins by cyclodextrin.. ...
http://eprints.iisc.ernet.in/13416/
pullulanase(EC 3.2.1.41) - Creative Enzymespullulanase(EC 3.2.1.41) - Creative Enzymes
Different from EC 3.2.1.142 (limit dextrinase) in its action on glycogen, and its rate of hydrolysis of limit dextrins. Its action on amylopectin is complete. Maltose is
https://www.creative-enzymes.com/product/Pullulanase_14073.html
Branching of cyclodextrins with various mono-, di-, and tri-saccharides by Bacillus acidophilus pullulanase. - Aalborg...Branching of cyclodextrins with various mono-, di-, and tri-saccharides by Bacillus acidophilus pullulanase. - Aalborg...
TY - GEN. T1 - Branching of cyclodextrins with various mono-, di-, and tri-saccharides by Bacillus acidophilus pullulanase.. AU - Madsen, U.. AU - Larsen, Kim Lambertsen. PY - 2002. Y1 - 2002. KW - Bioteknologi. KW - Bioteknologi. M3 - Article in proceeding. BT - Third Nordic Starch network Symposium. PB - Denmark.. ER - ...
https://vbn.aau.dk/en/publications/branching-of-cyclodextrins-with-various-mono-di-and-tri-saccharid
Photoresponsive nanostructured membranes - RSC Advances (RSC Publishing)Photoresponsive nanostructured membranes - RSC Advances (RSC Publishing)
The perspective of adding stimuli-response to isoporous membranes stimulates the development of separation devices with pores, which would open or close under control of environment chemical composition, temperature or exposure to light. Changes in pH and temperature have been previously investigated. In this work,
https://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C6RA14317B
Evolutionary Aspects of Photoresponsive Systems | SpringerLinkEvolutionary Aspects of Photoresponsive Systems | SpringerLink
A major factor in the survival of an organism is its ability to communicate with and respond to its environment. Among the environmental factors is a portion of the electromagnetic spectrum, from...
https://link.springer.com/chapter/10.1007/978-1-4757-0896-7_1
Novel cyclodextrin-based pH-sensitive supramolecular host-guest assembly for staining acidic cellular organelles - Polymer...Novel cyclodextrin-based pH-sensitive supramolecular host-guest assembly for staining acidic cellular organelles - Polymer...
The preparation and characterization of a supramolecular host-guest inclusion complex between a fluorescent indolizinyl-pyridinium salt and β-cyclodextrin is reported. The formation of the inclusion complex was investigated by ESI-MS experiments, transmission electron microscopy, Jobs plot investigations an
http://pubs.rsc.org/en/content/articlelanding/2018/py/c7py01668a
Potential use of folate-polyethylene glycol (PEG)-appended dendrimer (G3) conjugate with α-cyclodextrin as DNA carriers to...
We previously reported that polyamidoamine STARBURST dendrimer (generation 3, G3) (dendrimer) conjugate with α-cyclodextrin (α-CyD) having an average degree of substitution of 2.4 of α-CyD (α-CDE) provided remarkable aspects as novel carriers for
http://www.biomedsearch.com/nih/Potential-use-folate-polyethylene-glycol/22402627.html
Cyclodextrin ComplexesCyclodextrin Complexes
Zhiyuan Biological is one of the leading China cyclodextrin complexes manufacturers and suppliers, as a professional company, we have productive factory, which is able to produce high-quality cyclodextrin complexes at good price. Welcome to buy products from us.
http://www.cydextrins.com/cyclodextrin-complexes-1
Inclusion complex formation of cyclodextrin with its guest and their applicationsInclusion complex formation of cyclodextrin with its guest and their applications
OA Text is an independent open-access scientific publisher showcases innovative research and ideas aimed at improving health by linking research and practice to the benefit of society.
https://www.oatext.com/Inclusion-complex-formation-of-cyclodextrin-with-its-guest-and-their-applications.php
Publications | Gimzewski Lab
Zhang, W. et al. ORGN 414-Folding polyrotaxanes using secondary noncovalent bonding interactions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, (AMER CHEMICAL SOC 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2008). ...
http://gim.chem.ucla.edu/biblio?amp%3Bo=asc&%3Bamp%3Bs=title&%3Bf%5Bauthor%5D=596&%3Bs=author&s=author&o=desc
Publications | Gimzewski Lab
Zhang, W. et al. ORGN 414-Folding polyrotaxanes using secondary noncovalent bonding interactions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, (AMER CHEMICAL SOC 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2008). ...
http://gim.chem.ucla.edu/biblio?page=4&%3Bo=asc&%3Bamp%3Bs=title&%3Bf%5Bauthor%5D=354&s=type&o=desc&f%5Bauthor%5D=22
J David Warren - Beta cyclodextrins bind, stabi... | ACS NetworkJ David Warren - Beta cyclodextrins bind, stabi... | ACS Network
Publication Details (including relevant citation information): Nociari, M.M., Lehmann, G.L., Perez Bay, A.E., Radu, R.A., Jiang, Z., Goicochea,
https://communities.acs.org/docs/DOC-63496
Global Dextrin Sales Market Report 2017 : ReportsnReports
[102 Pages Report] Check for Discount on Global Dextrin Sales Market Report 2017 report by QYResearch Group. In this report, the global Dextrin market is valued at...
http://www.reportsnreports.com/reports/832716-global-dextrins-sales-market-report-2017.html
GlycoDrive™ - 100% Highly Branched Chain Cyclic DextrinGlycoDrive™ - 100% Highly Branched Chain Cyclic Dextrin
GlycoDrive™ was created with Highly Branched Cyclic Dextrin to be a high-performance source of carbohydrate super-fuel for athletes.
https://drivennutrition.net/product/glycodrive/
Α-CyclodextrinΑ-Cyclodextrin
... (alpha-cyclodextrin), sometimes abbreviated as α-CD, is a hexasaccharide derived from glucose. It is related to ... All cyclodextrins are white, water-soluble solids with minimal toxicity. Cyclodextrins tend to bind other molecules in their ... Then cyclodextrin glycosyltransferase (CGTase) is added for enzymatic conversion. CGTases produce diverse cyclodextrins. The ... The exterior surface of cyclodextrins is somewhat hydrophilic whereas the interior core is hydrophobic. α-Cyclodextrin is ...
https://en.wikipedia.org/wiki/Α-Cyclodextrin
Inhaled ciclosporinInhaled ciclosporin
Fukaya, H; Iimura, A; Hoshiko, K; Fuyumuro, T; Noji, S; Nabeshima, T (Aug 2003). "A cyclosporin A/maltosyl-alpha-cyclodextrin ...
https://en.wikipedia.org/wiki/Inhaled_ciclosporin
Dansyl chlorideDansyl chloride
The fluorescence of these sulfonamide adducts can be enhanced by adding alpha-cyclodextrin. Dansyl chloride is unstable in ...
https://en.wikipedia.org/wiki/Dansyl_chloride
Cyclomaltodextrin glucanotransferaseCyclomaltodextrin glucanotransferase
... alpha-cyclodextrin glucanotransferase, alpha-cyclodextrin glycosyltransferase, beta-cyclodextrin glucanotransferase, beta- ... The systematic name of this enzyme class is 1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing). Other ... "Rational design of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 to increase alpha-cyclodextrin ... cyclodextrin glycosyltransferase, gamma-cyclodextrin glycosyltransferase, cyclodextrin glycosyltransferase, cyclomaltodextrin ...
https://en.wikipedia.org/wiki/Cyclomaltodextrin_glucanotransferase
CyclodextrinCyclodextrin
GRN 000155, alpha-cyclodextrin;GRAS Notice No. GRN 000074, beta-cyclodextrin;GRAS Notice No. GRN 000046, gamma-cyclodextrin ... alpha)-cyclodextrin: 6 glucose subunits β (beta)-cyclodextrin: 7 glucose subunits γ (gamma)-cyclodextrin: 8 glucose subunits ... Alpha-, beta-, and gamma-cyclodextrin are all generally recognized as safe by the U.S. FDA. They have been applied for delivery ... This is very valuable especially for the food industry, as only alpha- and gamma-cyclodextrin can be consumed without a daily ...
https://en.wikipedia.org/wiki/Cyclodextrin
Supramolecular polymerSupramolecular polymer
"Self-assembled supramolecular hydrogels formed by biodegradable PEO-PHB-PEO triblock copolymers and alpha-cyclodextrin for ... By combining ferrocene dimer with β-cyclodextrin dimer, a redox-control supramolecular polymers system has been proposed as a ... Akira Harada was one of the firstwhorecognize the importance of combining polymers and cyclodextrins. Feihe Huang showed an ... cyclodextrins/adamantane derivatives, and pillar arene/imidazolium derivatives [30-33]. When the monomers are "heteroditopic", ...
https://en.wikipedia.org/wiki/Supramolecular_polymer
Gold cyanidationGold cyanidation
... and alpha-cyclodextrin. Challenges include reagent cost and the efficiency of gold recovery. Thiourea has been implemented ...
https://en.wikipedia.org/wiki/Gold_cyanidation
Glycoside hydrolase family 14Glycoside hydrolase family 14
Two maltose molecules also bind in the cleft, one sharing a binding site with alpha-cyclodextrin, and the other sitting more ... The 3D structure of a complex of soybean beta-amylase with an inhibitor (alpha-cyclodextrin) has been determined to 3.0A ... beta alpha)8 fold. The interface of the two domains, together with shorter loops from the (beta alpha)8 core, form a deep cleft ... preliminary chain tracing of the complex with alpha-cyclodextrin". Journal of Biochemistry. 112 (4): 541-6. doi:10.1093/ ...
https://en.wikipedia.org/wiki/Glycoside_hydrolase_family_14
Synthetic ion channelsSynthetic ion channels
... as supramolecular or covalent bonding of cyclodextrins to alpha-hemolysin demonstrates. An ion channel can be characterized by ... Other substituted β-cyclodextrins have since been reported, including thiol-modified cyclodextrins, an anion-selective ... Chui, J. K. W.; Fyles, T. M. (May 2010). "Apparent fractal distribution of open durations in cyclodextrin-based ion channels". ... The first synthetic ion channel was constructed by partial substitution on the primary rim of β-cyclodextrin. ...
https://en.wikipedia.org/wiki/Synthetic_ion_channels
List of MeSH codes (D09)List of MeSH codes (D09)
... cyclodextrins MeSH D09.698.365.855.400.375.222 - alpha-cyclodextrins MeSH D09.698.365.855.400.375.333 - beta-cyclodextrins MeSH ... D09.698.365.855.400.375.444 - gamma-cyclodextrins MeSH D09.698.365.855.500 - hetastarch MeSH D09.698.365.855.750 - inulin MeSH ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D09)
List of MeSH codes (D04)List of MeSH codes (D04)
... alpha-cyclodextrins MeSH D04.345.103.333 - beta-cyclodextrins MeSH D04.345.103.444 - gamma-cyclodextrins MeSH D04.345.241.308 ... 20-alpha-dihydroprogesterone MeSH D04.808.745.745.654.829.395 - hydroxyprogesterones MeSH D04.808.745.745.654.829.395.400 - 17- ... 5-alpha-dihydroprogesterone MeSH D04.808.745.558.050 - alfaxalone alfadolone mixture MeSH D04.808.745.558.783 - ... alpha-hydroxyprogesterone MeSH D04.808.745.745.654.829.614 - medroxyprogesterone MeSH D04.808.745.745.654.829.614.500 - ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D04)
Supramolecular catalysisSupramolecular catalysis
... hydrolysis of m-tert-butylphenyl acetate is accelerated in the presence of 2-benzimidazoleacetic acid and alpha-cyclodextrin, ... developed a catalyst based on a beta-cyclodextrin carrying two imidazole groups. This cyclodextrin catalytic system mimics ... Cyclodextrins have rigid ring structure, hydrophilic surface, and hydrophobic cavity on the inside; therefore, they are capable ... From the early 1970s, cyclodextrins have been extensively studied for its encapsulation properties and used as binding sites in ...
https://en.wikipedia.org/wiki/Supramolecular_catalysis
CucurbiturilCucurbituril
Mono-, Oligo- und Polyrotaxane mit Cucurbituril und gemischte Polyrotaxane mit Cucurbituril und alpha-Cyclodextrin mittels ... U.S. Patent 6,365,734 The complex formation of a, w-dicarboxylic acids and a, w-diols with cucurbituril and a-cyclodextrin. the ... Other common molecular capsules that share a similar molecular shape with cucurbiturils include cyclodextrins, calixarenes, and ...
https://en.wikipedia.org/wiki/Cucurbituril
Wolfram SaengerWolfram Saenger
Water Molecule in Hydrophobic Surroundings: Structure of alpha-Cyclodextrin-Hexahydrate (C6H10O5)6·6H2O, Nature, 1972 Circular ...
https://en.wikipedia.org/wiki/Wolfram_Saenger
Coordination sphereCoordination sphere
"Selective isolation of gold facilitated by second-sphere coordination with alpha-cyclodextrin" Nature Communications 2013, 4, ... Macrocyclic molecules such as cyclodextrins act often as the second coordination sphere for metal complexes. Coordination ...
https://en.wikipedia.org/wiki/Coordination_sphere
DNA sequencingDNA sequencing
... where the readout of electrical signals occurred as nucleotides passed by alpha(α)-hemolysin pores covalently bound with ... cyclodextrin. However the subsequent commercial method, 'strand sequencing', sequenced DNA bases in an intact strand. Two main ...
https://en.wikipedia.org/wiki/DNA_sequencing
HemolysinHemolysin
At the moment, apiegnin and beta-cyclodextrin are thought to alleviate S.aureus pneumonia, whereas the antibodies of anti alpha ... It produces a ring-shaped complex called a staphylococcal alpha-hemolysin pore. In nature, Staphylococcus aureus secretes alpha ... In this case, it has been proven that alpha-hemolysin takes part in inducing necrotic pulmonary injury by the use of the NLRP3 ... This pore consists of seven alpha-hemolysin subunits, which represent the major cytotoxic agent that is freed by this kind of ...
https://en.wikipedia.org/wiki/Hemolysin
DextrinDextrin
Cyclodextrin The cyclical dextrins are known as cyclodextrins. They are formed by enzymatic degradation of starch by certain ... Alpha) Limit dextrin is a short chained branched amylopectin remnant, produced by hydrolysis of amylopectin with alpha amylase ... that can be produced by enzymatic hydrolysis of the alpha-1,6 glycosidic bonds or debranching amylopectin. Amylodextrin colors ... which cannot hydrolyse the alpha-1,6 bonds at branch points. ( ... Cyclodextrins have toroidal structures formed by 6-8 glucose ...
https://en.wikipedia.org/wiki/Dextrin
Glycoside hydrolase family 13Glycoside hydrolase family 13
The maltogenic alpha-amylase is an enzyme which catalyses hydrolysis of (1-4)-alpha-D-glucosidic linkages in polysaccharides so ... which hydrolyses cyclodextrins. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G (July 1995). "Conserved ... as to remove successive alpha-maltose residues from the non-reducing ends of the chains in the conversion of starch to maltose ...
https://en.wikipedia.org/wiki/Glycoside_hydrolase_family_13
AlamandineAlamandine
Importantly, oral administration of an alamandine/2-hydroxypropyl β-cyclodextrin (HPβCD) complex produced an antihypertensive ... TNF alpha and CCL2) and pro-fibrotic factors (MMP2 and TGF β1), and increased pro-resolution markers (MRC1 and FIZZ1) Almandine ...
https://en.wikipedia.org/wiki/Alamandine
NeopullulanaseNeopullulanase
"Complex structures of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with acarbose and cyclodextrins demonstrate the multiple ... While most alpha-amylase enzymes only cleave alpha-1,4-linkages in their substrates, neopullulanase additionally cleaves alpha- ... 6-alpha-D-glucosylmaltose) The breakdown of the alpha-1,4- and alpha-1,6-glucosidic bonds of intermediates produced in addition ... These intermediates then have their alpha-1,4- and alpha-1,6-glucosidic bonds hydrolyzed to form additional panose along with ...
https://en.wikipedia.org/wiki/Neopullulanase
CamptothecinCamptothecin
CPT is linked to a cyclodextrin-based polymer to form the investigational anti-cancer drug CRLX101. Like all other ... Then this intermediate is converted to indole glycerol phosphate, which interacts with the alpha-subunit of tryptophan (TSA) ... First, chorismate is converted to anthranilate by the alpha-subunit of anthranilate synthase (ASA). Anthranilate reacts with 5- ... and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring). Its planar ...
https://en.wikipedia.org/wiki/Camptothecin
Anthony CzarnikAnthony Czarnik
Johnson, Todd (July 1, 2013). "Illumina - A Deeper Look Into A Genetic Technology Investment". Seeking Alpha. Retrieved 12 ... cyclodextrin". Journal of the American Chemical Society. 105 (5): 1390-91. doi:10.1021/ja00343a063. "Anthony W. Czarnik, Ph.D ...
https://en.wikipedia.org/wiki/Anthony_Czarnik
CycloamyloseCycloamylose
Chemically they are similar to the much smaller cyclodextrins, which are typically composed of 6, 7 or 8 glucose units. ... Takaha, T.; Yanase, M.; Okada, S.; Smith, S. M. (1993-01-15). "Disproportionating enzyme (4-alpha-glucanotransferase; EC 2.4. ... While the structures of cyclodextrins are planar circles, the structure of cycloamyloses with 10 to 14 glucose units were ... "Structures of the Common Cyclodextrins and Their Larger AnaloguesBeyond the Doughnut". Chemical Reviews. 98 (5): 1787-1802. doi ...
https://en.wikipedia.org/wiki/Cycloamylose
List of food additivesList of food additives
Carotenes - color Alpha-carotene - color Beta-carotene - color Gamma-carotene - color Carrageenan - thickener, vegetable gum, ... artificial sweetener beta-cyclodextrin - emulsifier Lemongrass (Cymbopogon citratus, C. flexuosus, and other species) - Damiana ... antioxidant Dl-alpha-tocopherol (synthetic) - antioxidant Dodecyl gallate - antioxidant Echinacea - EDTA - Antioxidant, ...
https://en.wikipedia.org/wiki/List_of_food_additives
List of biomoleculesList of biomolecules
... α-Cyclodextrin Cyclodextrin glycosyltransferase Cyclooxygenase Cyclopamine Cyclopiazonic acid Cysteine Cystine Cytidine ... Aequorin Aflatoxin Agar Alamethicin Alanine Albumins Aldosterone Aleurone Alpha-amanitin Alpha-MSH (Melaninocyte stimulating ... hormone) Allantoin Allethrin α-Amanatin, see Alpha-amanitin Amino acid Amylase (also see α-amylase) Anabolic steroid Anandamide ...
https://en.wikipedia.org/wiki/List_of_biomolecules
AcarboseAcarbose
However, bacterial alpha-amylases from gut microbiome are able to degrade acarbose. Pancreatic alpha-amylase hydrolyzes complex ... Park, Kwan-Hwa (2006). "Function and Tertiary- and Quaternary-structure of Cyclodextrin-hydrolyzing Enzymes (CDase), a Group of ... It has been reported that the maltogenic alpha-amylase from Thermus sp. IM6501 (ThMA) and a cyclodextrinase (CDase) from ... It is a starch blocker, and inhibits alpha glucosidase, an intestinal enzyme that releases glucose from larger carbohydrates. ...
https://en.wikipedia.org/wiki/Acarbose
CrystallopathyCrystallopathy
Crystal dissolvents have been under research, for example with cyclodextrin in atherosclerosis. Another approach would be to ... Finally, this activates the inflammatory response including the release of pro-inflammatory interleukin 1 alpha, interleukin 1 ... Paraproteins Amyloid beta peptides Amylin Transthyretin Alpha-synuclein Prions Uromodulin ASC speck complex Myoglobin Heme ...
https://en.wikipedia.org/wiki/Crystallopathy
ItraconazoleItraconazole
The cyclodextrin contained in the oral solution can cause an osmotic diarrhea, and if this is a problem, then half the dose can ... These distinct activities are unrelated to inhibition of the cytochrome P450 lanosterol 14 alpha-demethylase and the exact ... sometimes fatal The cyclodextrin used to make the syrup preparation can cause diarrhea. Side effects that may indicate a ... be given as oral solution and half as capsule to reduce the amount of cyclodextrin given.[citation needed] "Sporanox" ...
https://en.wikipedia.org/wiki/Itraconazole
Glycogen branching enzymeGlycogen branching enzyme
4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase. Other names in common use include branching ... cyclodextrin glucanotransferase (CGT), and branching enzyme. Shown by x-ray crystallography, glycogen branching enzyme has four ... 4-alpha-glucan branching enzyme 1, plant branching enzyme, alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase, and starch ... 1,4-alpha-glucan-branching enzyme, also known as brancher enzyme or glycogen-branching enzyme is an enzyme that in humans is ...
https://en.wikipedia.org/wiki/Glycogen_branching_enzyme
Ronald BreslowRonald Breslow
From figure 5, we see that the L alpha-methyl amino acids do not directly act as a chiral directing group to generate the ... and the rate enhancement provided by binding to cyclodextrins produced major themes for study in modern organic and biological ... Researchers hoped that a second molecule of the alpha-methy amino acid could act as a directing group, however they found that ... It's worth noting that the alpha keto acid is believed to be formed from a Strecker-like reaction, shown below. ...
https://en.wikipedia.org/wiki/Ronald_Breslow
ImatinibImatinib
A formulation of imatinib with a cyclodextrin (Captisol) as a carrier to overcome the blood-brain barrier has shown reversal of ... and the beta crystalline form as opposed to the alpha or other form.: 3 and 4 In 1998, Novartis filed international patent ...
https://en.wikipedia.org/wiki/Imatinib
Niemann-Pick disease, type CNiemann-Pick disease, type C
... cyclodextrin therapy. On January 23, 2013, a formal clinical trial to evaluate HPβCD cyclodextrin therapy as a treatment for ... cite journal ,vauthors=Rimkunas VM, Graham MJ, Crooke RM, Liscum L,title=TNF-{alpha} plays a role in hepatocyte apoptosis in ... the FDA granted Hydroxypropyl-beta-cyclodextrin orphan drug status and designated HPbCD cyclodextrin as a potential treatment ... Treatment with cyclodextrin has been shown to delay clinical disease onset, reduced intraneuronal storage and secondary markers ...
https://en.wikipedia.org/wiki/Niemann–Pick_disease,_type_C
Transporter Classification DatabaseTransporter Classification Database
Family 1.D.60 The Alpha,Gamma-Cyclic Peptide (AGCP) Family 1.D.61 The Anionophoric 2,6-Bis(Benzimidazol-2-yl)Pyridine (ABBP) ... family 1.B.26 Cyclodextrin porin (CDP) family 1.B.31 Campylobacter jejuni major outer membrane porin (MomP) family 1.B.32 ... Family 1.D.53 The alpha, gamma-Peptide Nanotube (a,gPepNT) Family 1.D.54 The potassium-selective Hexyl-Benzoureido-15-Crown-5- ... Ether Ion Channel (HBEC) Family 1.D.55 The Porphyrin-based Nanopore (PorNP) Family 1.D.56 The Alpha-Aminoisobutyrate (Aib) ...
https://en.wikipedia.org/wiki/Transporter_Classification_Database
Carbohydrate-binding moduleCarbohydrate-binding module
Isoamylase hydrolyses 1,6-alpha-D-glucosidic branch linkages in glycogen, amylopectin and dextrin; 1,4-alpha-glucan branching ... "The raw starch binding domain of cyclodextrin glycosyltransferase from Bacillus circulans strain 251". The Journal of ... Carbohydrate-binding module family 25 (CBM25) binds alpha-glucooligosaccharides, particularly those containing alpha-1,6 ... CBM27 adopts a beta sandwich structure comprising 13 beta strands with a single, small alpha-helix and a single metal atom. ...
https://en.wikipedia.org/wiki/Carbohydrate-binding_module
Saliva testingSaliva testing
Alpha amylase, on the other hand, spikes quickly when confronted with a stressor and returns to baseline soon after the stress ... with dimethyl-beta-cyclodextrin". Chem. Pharm. Bull. 45 (2): 378-83. doi:10.1248/cpb.45.378. PMID 9118452. Soell M, Feki A, ... Alpha amylase levels in saliva provide a non-invasive way to examine sympathoadrenal medullary (SAM) activity, which can ... Results showed that alpha amylase levels changed when reacting to competition, but not when anticipating it. Furthermore, by ...
https://en.wikipedia.org/wiki/Saliva_testing
Lobaria pulmonariaLobaria pulmonaria
... such as alpha carotene, beta carotene, and beta cryptoxanthin. The upper cortex of the lichen contains melanins that screen UV ... when the spores are grown in a synthetic growth medium containing an adsorbent like bovine serum albumin or α-cyclodextrin. ...
https://en.wikipedia.org/wiki/Lobaria_pulmonaria
SunscreenSunscreen
Cyclodextrins have demonstrated the ability to reduce photodecomposition, protect antioxidants and limit skin penetration past ... There is a growing amount of research demonstrating that adding various vitamer antioxidants (eg; retinol, alpha tocopherol, ... Yang, Jing; Wiley, Cody J.; Godwin, Donald A.; Felton, Linda A. (June 2008). "Influence of hydroxypropyl-β-cyclodextrin on ... "Sunscreens Containing Cyclodextrin Inclusion Complexes for Enhanced Efficiency: A Strategy for Skin Cancer Prevention". ...
https://en.wikipedia.org/wiki/Sunscreen
Porin (protein)Porin (protein)
... alpha )}}} and, tan ⁡ ( α ) = S a n b {\displaystyle \tan(\alpha )={\frac {Sa}{nb}}} Using these formulas, the structure of a ... family 1.B.26 Cyclodextrin porin (CDP) family 1.B.31 Campylobacter jejuni major outer membrane porin (MomP) family 1.B.32 ...
https://en.wikipedia.org/wiki/Porin_(protein)
alpha-Cyclodextrins | Semantic Scholaralpha-Cyclodextrins | Semantic Scholar
alpha-Cyclodextrins. Known as: alpha Cyclodextrins, alpha-Cyclodextrins [Chemical/Ingredient] Cyclic GLUCANS consisting of six ... The interactions of per (3,6 anhydro) alpha cyclodextrin (alpha 36CD) and of lead-alpha 36CD complex with biological systems ... Interaction of per 3,6-anhydro-alpha cyclodextrins (alpha 36CD) and lead-alpha 36CD complex with biological systems. ... The 1H NMR spectra of seven branched alpha-cyclodextrins (alpha-CDs) were observed and analyzed in detail. They were compared… ...
https://www.semanticscholar.org/topic/alpha-Cyclodextrins/1996406
Hexakis-(6-amino-6-deoxy)-alpha-Cyclodextrin hexahydrochlorideHexakis-(6-amino-6-deoxy)-alpha-Cyclodextrin hexahydrochloride
No: CDexA-013 This Product is available in multi-grams / kilogram pack size, please inquire at [email protected]cyclodextrin-shop.com ... Hexakis-(6-deoxy-6-mercapto)-alpha-Cyclodextrin. Product Name. : Hexakis-(6-deoxy-6-mercapto)-α-Cyclodextrin. ≥97%. ... Hexakis-(2,3,6-tri-O-acetyl)-alpha-Cyclodextrin. Product Name. : Hexakis-(2,3,6-tri-O-acetyl)-α-Cyclodextrin. ... Hexakis-(6-bromo-6-deoxy)-alpha-Cyclodextrin. Product Name. : Hexakis-(6-bromo-6-deoxy)-α-Cyclodextrin ≥97%. ...
http://www.cyclodextrin-shop.com/product/hexakis-6-amino-6-deoxy-alpha-cyclodextrin-hexahydrochloride/
Registration Dossier - ECHARegistration Dossier - ECHA
alpha.-Cyclodextrin-bvis-2-hydroxypropyletheralpha.-Cyclodextrin-bvis-2- ... alpha.-Cyclodextrin-tri-2-hydroxypropyletheralpha.-Cyclodextrin-tri-2- ... alpha.-Cyclodextrin-tetra-2-hydroxypropyletheralpha.-Cyclodextrin-tetra-2- ... alpha.-Cyclodextrin-penta-2-hydroxypropyletheralpha.-Cyclodextrin-penta-2- ...
https://www.echa.europa.eu/web/guest/registration-dossier/-/registered-dossier/19103/1/1
2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) - Molecular Depot2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) - Molecular Depot
... is a highly pure cyclic hydroxylated dextrin of type Alpha. This product has ... 5: Zarzycki PK, Ohta H, Saito Y, Jinno K. Interaction of native alpha-. cyclodextrin, beta-cyclodextrin and gamma-cyclodextrin ... 2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) is a highly pure solution of cyclic hydroxylated dextrin of type Alpha. ... 2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v). $295.00. $150.00. Catalog Number: K1010005B (25 mL). ( ...
https://moleculardepot.com/product/2-hydroxypropyl-alpha-cyclodextrin-solution-10-w-v/
Molecules | Free Full-Text | Optimization of Regioselective α-Glucosylation of Hesperetin Catalyzed by Cyclodextrin...Molecules | Free Full-Text | Optimization of Regioselective α-Glucosylation of Hesperetin Catalyzed by Cyclodextrin...
The regioselective α-glucosylation of hesperetin was achieved by a transglycosylation reaction catalyzed by cyclodextrin ... of cyclodextrin glycosyltransferase from Thermoanaerobacter causes a shift from cyclodextrin glycosyltransferase to alpha- ... The cyclodextrin glucanotransferase (CGTase) from Thermoanaerobacter sp. (Toruzyme 3.0 L) was kindly provided by Novozymes A/S ... Han, R.; Ge, B.; Jiang, M.; Xu, G.; Dong, J.; Ni, Y. High production of genistein diglucoside derivative using cyclodextrin ...
https://www.mdpi.com/1420-3049/23/11/2885
Cyclodextrin Market Size, Share, Trends | Industry Forecast Report 2029Cyclodextrin Market Size, Share, Trends | Industry Forecast Report 2029
Growing use of cyclodextrins in food manufacturing as food additives for different purposes is anticipated to be a growth ... Alpha-cyclodextrin, beta-cyclodextrin, & gamma-cyclodextrin are the three main types of cyclodextrin. Beta-cyclodextrin is ... Alpha-cyclodextrin, beta-cyclodextrin, & gamma-cyclodextrin are the three main types of cyclodextrin. Beta-cyclodextrin is ... Cyclodextrin Market by Type (alpha-cyclodextrin, beta-cyclodextrin, gamma-cyclodextrin, cd derivatives), Application (food & ...
https://www.adroitmarketresearch.com/industry-reports/cyclodextrin-market
Zibo Qianhui Biological Technology Co., Ltd.-Beta cyclodextrin series| Alpha cyclodextrin series Beta cyclodextrin series,Gamma...
For Hydroxypropyl Beta Cyclodextrin, we has got the accepted registration DMF number (033403) from USFDA and ranks up in China ... Alpha Cyclodextrin Series Beta Cyclodextrin Series Gamma Cyclodextrin Series Cyclodextrin Inclusion Compound Series ... Alpha Cyclodextrin Series Beta Cyclodextrin Series Gamma Cyclodextrin Series Cyclodextrin Inclusion Compound Series ... Alpha Cyclodextrin Series Beta Cyclodextrin Series Gamma Cyclodextrin Series Cyclodextrin Inclusion Compound Series ...
https://www.ziboqianhui.com/
ALPHA LIPOIC ACID AMINO ACIDS BETA CYCLO DEXTRIN (BCD/HPBCD/SBECD) CARBOMERS CITRIC ACID IP CREATINE MONOHYDRATE FUMED SILICA (...ALPHA LIPOIC ACID AMINO ACIDS BETA CYCLO DEXTRIN (BCD/HPBCD/SBECD) CARBOMERS CITRIC ACID IP CREATINE MONOHYDRATE FUMED SILICA (...
ALPHA LIPOIC ACID AMINO ACIDS BETA CYCLO DEXTRIN (BCD/HPBCD/SBECD) CARBOMERS CITRIC ACID IP CREATINE MONOHYDRATE FUMED SILICA ... ALPHA LIPOIC ACID. AMINO ACIDS. BETA CYCLO DEXTRIN (BCD/HPBCD/SBECD). CARBOMERS. CITRIC ACID IP. CREATINE MONOHYDRATE. FUMED ... ALPHA LIPOIC ACID AMINO ACIDS BETA CYCLO DEXTRIN (BCD/HPBCD/SBECD) CARBOMERS CITRIC ACID IP CREATINE MONOHYDRATE FUMED SILICA ... ALPHA LIPOIC ACID AMINO ACIDS BETA CYCLO DEXTRIN (BCD/HPBCD/SBECD) CARBOMERS CITRIC ACID IP CREATINE MONOHYDRATE FUMED SILICA ...
https://www.cphi-online.com/alpha-lipoic-acid-amino-acids-beta-cyclo-dextrin-prod1273423.html
EP0254588A1 - Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same ...
229920001450 Alpha-Cyclodextrin Polymers 0.000 description 1 * PZZYQPZGQPZBDN-UHFFFAOYSA-N Aluminium silicate Chemical compound ... 229920000858 Cyclodextrin Polymers 0.000 description 2 * VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound data:image/svg+xml; ...
https://patents.google.com/patent/EP0254588A1/en
Edex (Alprostadil for Injection): Uses, Dosage, Side Effects, Interactions, WarningEdex (Alprostadil for Injection): Uses, Dosage, Side Effects, Interactions, Warning
Alpha-Cyclodextrin After reconstitution, PGE1 immediately dissociates from the α-cyclodextrin inclusion complex; the in ... The α-cyclodextrin inclusion complex improves the water solubility of alprostadil. The empirical formula of α-cyclodextrin is C ... 347.55 mcg α-cyclodextrin, 51.06 mg lactose); 20 mcg cartridge (21.5 mcg alprostadil, 695.2 mcg α-cyclodextrin, 51.06 mg ... edex® (alprostadil for injection) is a sterile, pyrogen-free powder containing alprostadil in an alfadex (α-cyclodextrin) ...
https://www.rxlist.com/edex-drug.htm
SCOP 1.69: Species: Bacillus stearothermophilus, maltogenic alpha-amylaseSCOP 1.69: Species: Bacillus stearothermophilus, maltogenic alpha-amylase
Timeline for Species Bacillus stearothermophilus, maltogenic alpha-amylase [TaxId:1422] from b.3.1.1 Cyclodextrin ... More info for Species Bacillus stearothermophilus, maltogenic alpha-amylase [TaxId:1422] from b.3.1.1 Cyclodextrin ... Species Bacillus stearothermophilus, maltogenic alpha-amylase [TaxId:1422] from b.3.1.1 Cyclodextrin glycosyltransferase, C- ... Species Bacillus stearothermophilus, maltogenic alpha-amylase [TaxId:1422] from b.3.1.1 Cyclodextrin glycosyltransferase, C- ...
http://scop.berkeley.edu/sunid=49457&ver=1.69
Aref WAZWAZ | Professor (Associate) | Associate Professor | Dhofar University, Şalālah | Department of Chemical EngineeringAref WAZWAZ | Professor (Associate) | Associate Professor | Dhofar University, Şalālah | Department of Chemical Engineering
Determination inclusion constants of alpha, beta -cyclodextrins with Abo-dyes (methyl orange , methyl red). It is a kinetic ...
https://www.researchgate.net/profile/Aref-Wazwaz
Advances in Hybrid Polymer-Based Materials for Sustained Drug ReleaseAdvances in Hybrid Polymer-Based Materials for Sustained Drug Release
Cyclodextrins (CD) are cyclic oligosaccharides composed of glucopyranose units, joined by 1.4 alpha linkages [60]. CD are ... Cyclodextrins. Since 1970, biotechnological advances allowed the purification and production of cyclodextrins to be applied as ... H. Y. Zhou, Z. Y. Wang, X. Y. Duan et al., "Design and evaluation of chitosan-β-cyclodextrin based thermosensitive hydrogel," ... R. Challa, A. Ahuja, J. Ali, and R. K. Khar, "Cyclodextrins in drug delivery: an updated review," AAPS PharmSciTech, vol. 6, no ...
https://www.hindawi.com/journals/ijps/2017/1231464/
China raw material pharmaceutical factoriesChina raw material pharmaceutical factories
":"CAS 10016-20-3 raw material pharmaceutical Alpha - Cyclodextrin Alfadex","company_name":"SBS BIOTECH CO.,LTD","attrs":{" ...
https://www.ecer.com/china-raw-material-pharmaceutical
Gold: Facts, history and uses of the most malleable chemical element | Live ScienceGold: Facts, history and uses of the most malleable chemical element | Live Science
While trying to fabricate a porous material, the researchers mixed a starch called alpha-Cyclodextrin with gold salts (charged ... The anti-cancer drug TNF-alpha kills cancer very effectively. Unfortunately, its also incredibly toxic to healthy cells. ... However, clinical trials now underway have found that linking TNF-alpha drugs to gold nanoparticles can successfully treat ...
https://www.livescience.com/39187-facts-about-gold.html
NHANES 1999-2000: Cholesterol - Total & HDL Data Documentation, Codebook, and Frequencies
The method uses sulfated alpha-cyclodextrin in the presence of Mg+2 , which forms complexes with apoB containing lipoproteins, ... ApoB containing lipoproteins + a-cyclodextrin + Mg+2 + dextran SO4 ---, soluble non-reactive complexes with apoB-containing ...
https://wwwn.cdc.gov/Nchs/Nhanes/1999-2000/LAB13.htm
Xenopus Anatomy Ontology: Papers for Xenopus Anatomy Ontology: Papers for
Effects of alpha-cyclodextrin on water transport, cell hydration and longevity., Szente L., Aging (Albany NY). January 19, 2021 ...
https://www.xenbase.org/entry/anatomy/attribution.do?objId=3344&objName=ANATOMY_ITEM&objNameSrt=ANAT&attPage=PAPER&action=VIEW&litOnly=1&att=&pageType=ANAT&tabId=1
Options for sourcing 1-MCP for 2021 - ApplesOptions for sourcing 1-MCP for 2021 - Apples
SmartFresh (3.3% active ingredient) is a formulation of 1-MCP that is encapsulated in a material known as alpha cyclodextrin. ... Easyfresh is a cyclodextrin-based 1-MCP formulation, much like SmartFresh. Also like SmartFresh, it is handled in dissolvable ... FirmConfirm is a cyclodextrin-based 1-MCP formulation, much like SmartFresh. Also like SmartFresh, it is handled in dissolvable ... Upon the addition of water, the cyclodextrin dissolves and the 1-MCP is liberated as a gas. ...
https://www.canr.msu.edu/news/options-for-sourcing-1-mcp
Sciencemadness Discussion Board - Alcohol Powder... How? - Powered by XMB 1.9.11Sciencemadness Discussion Board - Alcohol Powder... How? - Powered by XMB 1.9.11
Cyclodextrin (alpha) has an appropriate cavity size, but the internal cavity for the guest-host relationship is hydrophobic. ...
http://www.sciencemadness.org/talk/viewthread.php?tid=8603#pid98560
US Patent Application for TETRAHYDRO-ISOHUMULONE DERIVATIVES, METHODS OF MAKING AND USING Patent Application (Application ...US Patent Application for TETRAHYDRO-ISOHUMULONE DERIVATIVES, METHODS OF MAKING AND USING Patent Application (Application ...
The trans iso-alpha acids were removed via β-cyclodextrin complexation (Khatib 2010) from 45 g of a hops isomerized resin ... Alpha acids can be converted to cis or trans iso-alpha acids/isohumulones by heat-induced isomerization of alpha acids, and ... The three primary types of reduced iso-alpha acids are dihydro- (also known as rho-), tetrahydro-, and hexahydro-iso-alpha ... starting with the alpha acids (which naturally have (-) optical rotation) and continuing through to the isomerized alpha acids ...
https://patents.justia.com/patent/20150119461
Articles
Temperature sensitive supramolecular self assembly of per-6-PEO-beta-cyclodextrin and alpha, omega-di-(adamantylethyl)poly(N- ... Polyrotaxanes of pyrene-triazole conjugated azomethine and alpha-cyclodextrin with high fluorescence properties. A. Farcas, N. ... Regioselective allylation of cyclodextrin leading to per(2,6-di-O-hydroxypropyl-3-O-methyl)-β-cyclodextrin. Z. Eskandani, C. ... Beta-Cyclodextrins modified by alkyl and poly(ethylene oxide) chains : A novel class of mass transfer additives for aqueous ...
https://www.lambe.univ-evry.fr/productions-scientifiques/publications/articles.html
Delgado-Charro, B.<...
c. Trichard et al., Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug, Pharm Res. 25 ( ...
https://researchportal.bath.ac.uk/en/persons/begona-delgado-charro
Chemistry: Green recovery of gold | Nature Communications | Nature Portfolio
The process relies on the perfect "host-guest" interaction between gold bromide salts and alpha-cyclodextrin - a simple, non- ... Fraser Stoddart and colleagues show that the "supramolecular" interactions between alpha-cyclodextrin and gold salts allow the ...
https://www.natureasia.com/ko-kr/chemistry/research/8457
TBI - Theoretical Biochemistry Group - Publications - 2019-2010
Encapsulation of alpha-mangostin and hydrophilic beta-cyclodextrins revealed by all-atom molecular dynamics simulations. J Mol ... The inclusion complexation of daidzein with β-cyclodextrin and 2,6-dimethyl-β-cyclodextrin: a theoretical and experimental ... Molecular Dynamics Simulations of the Interaction of Beta Cyclodextrin with a Lipid Bilayer. J. Chem. Inf. Model., 2015, 55 (9 ... Binding mode and free energy prediction of fisetin/β-cyclodextrin inclusion complexes. Beilstein J. Org. Chem. 2014, 10, 2789- ...
https://www.tbi.univie.ac.at/publications/2019-2010.html
ARCONA Advanced A Serum (1.17 oz.) - Dermstore ARCONA Advanced A Serum (1.17 oz.) - Dermstore
Cyclodextrin, Tocopherol (D-alpha), Aloe Barbadensis Leaf Juice Powder*, Per+ uorohexane, Lonicera Caprifolium (Honeysuckle) ... Cyclodextrin, Tocopherol (D-alpha), Aloe Barbadensis Leaf Juice Powder*, Per+ uorohexane, Lonicera Caprifolium (Honeysuckle) ... Ingredient: Alpha Hydroxy Acids, Antioxidants, Honey, Lactic Acid, Peptides, Retinol, Vitamin A, Vitamin C. Preferences: ... Ingredient: Alpha Hydroxy Acids, Antioxidants, Honey, Lactic Acid, Peptides, Retinol, Vitamin A, Vitamin C. Preferences: ...
https://www.dermstore.com/arcona-advanced-a-serum-1.17oz/11294781.html?rctxt=default
Vitamin B12 (Cyanocobalamin) 68-19-9 - NO.135105Vitamin B12 (Cyanocobalamin) 68-19-9 - NO.135105
Alpha-Cyclodextrin, Alpha-CD; 10016-20-3 Alpha-Cyclodextrin, Alpha-CD; 10016-20-3 Other Names Cyclodextrin, Alpha-CD Grade ... Alpha Lipoic Acid 1077-28-7 Alpha Lipoic Acid 1077-28-7 Synonyms: DL-alpha-Lipoic acid; DL-6, 8-Dithiooctanoic acid; 5-( ... Beta-Cyclodextrin 7585-39-9 Beta-Cyclodextrin 7585-39-9 Feature: Beta Cyclodextrin is a cyclic heptamer composed of seven ... Beta-Cyclodextrin, 7585-39-9 Beta-Cyclodextrin, 7585-39-9 Category: fine chemical, food additive, Pharmaceutical excipients; ...
http://www.trader-china.com/Chemicals/Chemical-Machinery/Vitamin-B12-Cyanocobalamin-68-19-9-l135105.html
Cyclodextrins (CDs) For food chemical agricultural other industries industry for Amercial market - Xino Steel GroupCyclodextrins (CDs) For food chemical agricultural other industries industry for Amercial market - Xino Steel Group
Beta-cyclodextrin,ganma-cyclodextrins,α-cyclodextrin. Wholesale Cyclodextrins (CDs) For food chemical agricultural other ... Alpha-cyclodextrin,α-cyclodextrin,β-cyclodextrin, Beta-cyclodextrin γ-cyclodextrin,ganma-cyclodextrins ... Cyclodextrins (CDs) Cyclodextrins (CDs) For food chemical agricultural other industries industry for Amercial market. Read More ... Cyclodextrins (CDs) For food industry Brand. XINO. Price. USD 700/kgOB. Material. α β γ. Steel Grade. α β γ. Lead Time. 30 days ...
https://www.chinaxinogroup.com/Cyclodextrins--CDs--For-food--chemical--agricultural-other-industries-industry-for-Amercial-market_71.html
Formulating Sunless Tanning Products with DHA: Current Challenges | Cosmetics & ToiletriesFormulating Sunless Tanning Products with DHA: Current Challenges | Cosmetics & Toiletries
To sequester the offending odor molecules in sunless tanning formulations, cyclodextrins have been utilized.10 Complexation of ... Comparison of flavor retention in alpha, beta and gamma types, J of Food Science 67(9) 3271-3279 (2002) ... cyclodextrins with flavor chemicals can be achieved by simply mixing the two in an aqueous solution.11, 12 While cyclodextrins ... TA Reineccius, GA Reineccius and TL Peppard, Encapsulation of flavors using cyclodextrins: ...
https://www.cosmeticsandtoiletries.com/formulas-products/color-cosmetics/article/21835185/formulating-sunless-tanning-products-with-dha-current-challenges
HydrateComplexationMolecularAqueousPolymersCyclicSupramolecularEtherCarbohydrateSolubilityInclusion compoundDerivativeChemicalCompoundsGammaComplexesDerivativesPowderSubstance1997ClosureStabilityProductsPharmaceutical2021BetaCosmeticWaterBiologicalMarketBranched-chainFoodEffectsPricesFeaturesActiveIndustryCommon
Hydrate2
  • Crystal structure of a new alpha-cyclodextrin hydrate form. (semanticscholar.org)
  • Structure and stability of columnar cyclomaltooctaose (gamma-cyclodextrin) hydrate. (ncsu.edu)
Complexation7
  • The effect of water and guest hydrophobicity on the complexation of oligomers with solid alpha-cyclodextrin. (ncsu.edu)
  • The effect of water on the solid-state complexation of oligomers with a?cyclodextrin. (ncsu.edu)
  • Solid-state complexation of poly(ethylene glycol) with alpha-cyclodextrin. (ncsu.edu)
  • 4: Holm R, Schönbeck C, Askjær S, Jensen H, Westh P, Østergaard J. Complexation of tauro- and glyco-conjugated bile salts with α-cyclodextrin and hydroxypropyl- α-cyclodextrin studied by affinity capillary electrophoresis and molecular modelling. (moleculardepot.com)
  • 6: Liu B, Li W, Nguyen TA, Zhao J. Empirical, thermodynamic and quantum-chemical investigations of inclusion complexation between flavanones and (2-hydroxypropyl)-cyclodextrins. (moleculardepot.com)
  • 10 Complexation of cyclodextrins with flavor chemicals can be achieved by simply mixing the two in an aqueous solution. (cosmeticsandtoiletries.com)
  • We produced functional nanowebs, containing vanillin, having prolonged shelf-life and high temperature stability facilitated by cyclodextrin (CD) inclusion complexation. (bilkent.edu.tr)
Molecular2
  • 5: Zarzycki PK, Ohta H, Saito Y, Jinno K. Interaction of native alpha- cyclodextrin, beta-cyclodextrin and gamma-cyclodextrin and their hydroxypropyl derivatives with selected organic low molecular mass compounds at elevated and subambient temperature under RP-HPLC conditions. (moleculardepot.com)
  • The empirical formula of α-cyclodextrin is C 36 H 60 O 30 and the molecular weight is 972.85. (rxlist.com)
Aqueous1
  • 4-thiothymidine and water-soluble cyclodextrins: Evidence for supramolecular structures in aqueous solutions. (moleculardepot.com)
Polymers2
  • Reorganization and improvement of bulk polymers by processing with their cyclodextrin inclusion compounds. (ncsu.edu)
  • Cyclodextrins bridged with an ammonium linker which bears a hydrophobic substituent efficiently form supramolecular polymers, avoiding the competing self-inclusion and head-to-head processes. (ipcm.fr)
Cyclic2
  • 2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) is a highly pure solution of cyclic hydroxylated dextrin of type Alpha. (moleculardepot.com)
  • Cyclodextrins are a type of cyclic oligosaccharide that comprised of a macrocyclic ring with glucose units connected by 1,4 glycosidic linkages. (adroitmarketresearch.com)
Supramolecular1
  • Fraser Stoddart and colleagues show that the "supramolecular" interactions between alpha-cyclodextrin and gold salts allow the effective and selective recovery of gold from simulated and real waste materials, even in the presence of similar metals such as platinum and palladium. (natureasia.com)
Ether1
  • Sulfobutyl ether beta cyclodextrin sodium, a new injectable excipient independently researched and developed by the company, is the first new excipient (registered as "A") passing technical review with associated drug product and fills in the market gap in China. (ziboqianhui.com)
Carbohydrate1
  • The process relies on the perfect "host-guest" interaction between gold bromide salts and alpha-cyclodextrin - a simple, non-toxic carbohydrate that can be produced from starch. (natureasia.com)
Solubility2
  • Cyclodextrin is used in the cosmetic industry to improve the product's stability and solubility. (adroitmarketresearch.com)
  • The α-cyclodextrin inclusion complex improves the water solubility of alprostadil. (rxlist.com)
Inclusion compound2
  • Nonoxynol-9-alpha-cyclodextrin inclusion compound and its application for the controlled release of nonoxynol-9 spermicide. (ncsu.edu)
  • An intimate polycarbonate/poly(methyl methacrylate)/poly(vinyl acetate) ternary blend via coalescence from their common inclusion compound with gamma-cyclodextrin. (ncsu.edu)
Derivative2
  • The company specializes in production of pharmaceutical excipients, food and cosmetic additives that consist mainly of cyclodextrin and its derivative. (ziboqianhui.com)
  • Furthermore, the self-assembling cyclodextrin derivative interacts in a highly cooperative manner with DNA as demonstrated by compaction experiments. (ipcm.fr)
Chemical1
  • Wacker Chemie, the Munich-based chemical company, announced that is has expanded its US based cyclodextrin facility in Eddyville, Iowa. (addiandcassi.com)
Compounds2
  • Crystalline cyclodextrin inclusion compounds formed with aromatic guests: Guest-dependent stoichiometries and hydration-sensitive crystal structures. (ncsu.edu)
  • Cyclodextrin can also help safeguard the environment by reducing the number of harmful compounds produced during industrial production. (adroitmarketresearch.com)
Gamma3
  • The global cyclodextrin market is classified into alpha-cyclodextrin, beta-cyclodextrin, gamma-cyclodextrin, and cd derivatives on the basis of type. (adroitmarketresearch.com)
  • According the the press release issued by Wacker, the new cyclodextrin facility increases the company's capacity for alpha (α) and beta (β) cyclodextrins by 50 percent and doubles its capacity for gamma (γ) cyclodextrins. (addiandcassi.com)
  • Global Cyclodextrins By Product Type (Alpha- Cyclodextrin, Beta- Cyclodextrin and Gamma-Cyclodextrin. (4mark.net)
Complexes4
  • Effect of guest hydrophobicity on water sorption behavior of oligomer/alpha-cyclodextrin inclusion complexes. (ncsu.edu)
  • Two-phase channel structures based on alpha-cyclodextrin-polyethylene glycol inclusion complexes. (ncsu.edu)
  • 10: Kimura K, Hirayama F, Arima H, Uekama K. Solid-state 13C nuclear magnetic resonance spectroscopic study on amorphous solid complexes of tolbutamide with 2-hydroxypropyl-alpha- and -beta-cyclodextrins. (moleculardepot.com)
  • The method uses sulfated alpha-cyclodextrin in the presence of Mg +2 , which forms complexes with apoB containing lipoproteins, and polyethylene glycol-coupled cholesteryl esterase and cholesterol oxidase for the HDL-cholesterol measurement. (cdc.gov)
Derivatives2
  • Study on complex formation of biologically active pyridine derivatives with cyclodextrins by capillary electrophoresis. (moleculardepot.com)
  • The first attempts to identify the stereochemical configuration of the alpha acids and their derivatives were incorrect, starting with the alpha acids (which naturally have (-) optical rotation) and continuing through to the isomerized alpha acids. (justia.com)
Powder1
  • edex® (alprostadil for injection) is a sterile, pyrogen-free powder containing alprostadil in an alfadex (α-cyclodextrin) inclusion complex. (rxlist.com)
Substance1
  • After the presence of cyclodextrin s, trichlorfon, a poisonous substance, may be poisoned, and ninety percent of the hazardous components can be eliminated. (adroitmarketresearch.com)
19971
  • Among polymeric carriers, cyclodextrins (CD) have unique inclusion complex formation properties, even though their use as carriers (1997) was only described 100 years after their isolation [ 7 ]. (hindawi.com)
Closure1
  • The manufacturing for cyclodextrins has been hampered by the closure of many factories in European Union, Asia, and other regions. (adroitmarketresearch.com)
Stability1
  • 11, 12 While cyclodextrins could improve the shelf stability of formulations by absorbing degradation products over time, it is unclear whether they are available to sequester the malodor that forms hours after application of the sunless tanner. (cosmeticsandtoiletries.com)
Products4
  • The demand for cyclodextrin increased as the number of food manufacturing companies grew, as did the intake of dietary products including such mayonnaise and whipped cream. (adroitmarketresearch.com)
  • The increasing beauty awareness and grooming trend around the world is driving up cosmetics and personal care products usage, which is expected to drive up prices for cyclodextrin. (adroitmarketresearch.com)
  • Cyclodextrin is in high demand, particularly in the personal care products industries in the United States. (adroitmarketresearch.com)
  • Stack Includes 2 Bottles Stano TD 2 Bottles Alpha Stano Two of the best Epiandrosterone products on the market, paired together! (alphagainz.com)
Pharmaceutical2
  • Because cyclodextrin is also utilised in medicine, demand for it is projected to increase in the future as the pharmaceutical industry grows. (adroitmarketresearch.com)
  • Hydroxypropyl-beta-cyclodextrin, CDE platform - pharmaceutical excipient registration No.: F20209990335 (oral administration, activated, Lu Yao Zhun Zi F2012004), F20180000146 (oral administration) and F20180000895 (injection), U.S. FDA registration No.: DMF 033403. (ziboqianhui.com)
20211
  • Método: Examen retrospectivo de archivos de 112 pacientes operados de tiroides, y que tenían un diagnóstico postoperatorio de VFCPT en nuestro centro entre los años 2010 y 2021. (bvsalud.org)
Beta4
  • Hops contains both alpha acids (humulones) and beta acids (lupulones). (justia.com)
  • Permethylated NHC‐capped alpha‐ and beta-cyclodextrins (ICyDMe) Regioselective and enantioselective gold‐catalysis in pure water. (ipcm.fr)
  • NHC-capped cyclodextrin ligands, derived from alpha- and beta-cyclodextrins give opposite regioselectivities in a copper-catalyzed hydroboration. (ipcm.fr)
  • Esse software foi originalmente criado por Jens Duttke PhotoME Beta-Release GRATUIT pour Windows (PC) en Téléchargement de Confiance. (vegentempsabba.com)
Cosmetic1
  • The global cyclodextrin market is classified into food & drinks, pharmaceuticals, and cosmetic on the basis of application. (adroitmarketresearch.com)
Water2
  • Effects of alpha-cyclodextrin on water transport, cell hydration and longevity. (xenbase.org)
  • Upon the addition of water, the cyclodextrin dissolves and the 1-MCP is liberated as a gas. (msu.edu)
Biological1
  • Interaction of per 3,6-anhydro-alpha cyclodextrins (alpha 36CD) and lead-alpha 36CD complex with biological systems. (semanticscholar.org)
Market9
  • Rising application of cyclodextrins in food manufacturing as food additive for different purposes is driving the global cyclodextrins market. (adroitmarketresearch.com)
  • The global Cyclodextrin market size is expected to reach close to USD 390 million by 2029 with an annualized growth rate of 5.5% through the projected period. (adroitmarketresearch.com)
  • The global cyclodextrin market was severely hampered by the COVID-19 contagion, which has hampered the expansion of different sectors. (adroitmarketresearch.com)
  • However, since lockdown restrictions have removed and businesses are regaining momentum the global cyclodextrin market growing. (adroitmarketresearch.com)
  • Among these, the alpha-cyclodextrin segment accounted for highest market value due to increased demand for alpha-cyclodextrin across industries like food and cosmetics. (adroitmarketresearch.com)
  • Because of the larger use of cyclodextrin in numerous end-use sectors in the region, North America has a significant cyclodextrin market share. (adroitmarketresearch.com)
  • The worldwide cyclodextrin market is expected to grow at a fast pace in developing countries like South Asia and East Asia, addition to higher demand by consumer goods makers and increased use in pharmaceuticals. (adroitmarketresearch.com)
  • The growing use of cyclodextrin to reduce carbon emissions presents a growth potential for the global cyclodextrin market. (adroitmarketresearch.com)
  • The Global Cyclodextrin Market is estimated to grow at a 3.8 percent CAGR in sales over the following five years, reaching US$ 250 billion by 2029. (adroitmarketresearch.com)
Branched-chain1
  • 1H NMR spectra of branched-chain cyclomaltohexaoses (alpha-cyclodextrins). (semanticscholar.org)
Food2
  • Cyclodextrin has become a prominent component in the food preparation and cosmetics and beauty industries, resulting in cyclodextrin use is being restricted during the pandemic. (adroitmarketresearch.com)
  • Among these, the food and drinks segment witnessed more demand for cyclodextrin. (adroitmarketresearch.com)
Effects2
  • H, Higaki K, Hayashi A, Komiya T, Ishitsuka Y, Irie T. Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in Npc1 -Null Cells. (moleculardepot.com)
  • 3: Motoyama K, Hashimoto Y, Hirayama F, Uekama K, Arima H. Inhibitory effects of 2,6-di-O-methyl-alpha-cyclodextrin on poly I:C signaling in macrophages. (moleculardepot.com)
Prices1
  • Before buying cyclodextrins I check the other suppliers to compare prices and availability. (chinaxinogroup.com)
Features1
  • Introducción: A pesar de los definidos criterios diagnósticos recientemente propuestos para la neoplasia folicular de tiroides no invasiva con características de tipo papilar, designada con el acrónimo NIFTP de sus siglas en inglés (non-invasive follicular thyroid neoplasm with papillary-like nuclear features), todavía no se conoce su incidencia real. (bvsalud.org)
Active1
  • After reconstitution, the active ingredient, alprostadil, immediately dissociates from the α-cyclodextrin inclusion complex. (rxlist.com)
Industry1
  • The cyclodextrin industry was also hampered by trade restrictions and supply chain interruptions. (adroitmarketresearch.com)
Common1
  • There are also two less common alpha acids in hops, prehumulone and posthumulone. (justia.com)
Geregistreerde stoffen - ECHA
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Recently Published GRAS Notices and FDA Letters | FDA
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Edex (Alprostadil for Injection): Uses, Dosage, Side Effects, Interactions, Warning
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SCOP 1.69: Species: Bacillus stearothermophilus, maltogenic alpha-amylase
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Advances in Hybrid Polymer-Based Materials for Sustained Drug Release
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China raw material pharmaceutical factories
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Gold: Facts, history and uses of the most malleable chemical element | Live Science
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Xenopus Anatomy Ontology: Papers for
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Molecules | Free Full-Text | Optimization of Regioselective α-Glucosylation of Hesperetin Catalyzed by Cyclodextrin...
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Options for sourcing 1-MCP for 2021 - Apples
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SCOP 1.71: Domain d1qhpa3: 1qhp A:408-495
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Delgado-Charro, B.<...
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ARCONA Advanced A Serum (1.17 oz.) - Dermstore
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Cholesterol lowering drug | The Addi and Cassi Fund - Niemann Pick Type C
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Buy NA-R-ALA Stabilized R-Lipoic Acid Capsules 125mg | NARALA
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2-hydroxypropyl)-alpha-cyclodextrin Solution 10% (w/v) - Molecular Depot
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Sanmartín Grijalba, Carmen. CV. Nuestros investigadores. Investigación. Universidad de Navarra
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Großhandel von Rohstoffen Chemikalien - biolla chemicals
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Round, A.<...
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PROMAZINE
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Magnesiumsulfat 7-Hydrat - CAS 10034-99-8 - biolla DE
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Cyclodextrin News
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Cyclolab
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Sugabose A - 30 sachets - Shop.AyushNatural.com
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