Cyclodextrins: A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.alpha-Cyclodextrins: Cyclic GLUCANS consisting of six (6) glucopyranose units linked by 1,4-glycosidic bonds.beta-Cyclodextrins: Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.gamma-Cyclodextrins: Cyclic GLUCANS consisting of eight (8) glucopyranose units linked by 1,4-glycosidic bonds.DextrinsTrimeprazine: A phenothiazine derivative that is used as an antipruritic.Rotaxanes: Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS.Solubility: The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Starch: Any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin. It is the chief storage form of energy reserve (carbohydrates) in plants.Chemistry, Pharmaceutical: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.Micromonosporaceae: A family of gram-positive, saprophytic bacteria occurring in soil and aquatic environments.Optical Rotation: The rotation of linearly polarized light as it passes through various media.Sun Protection Factor: A measure of relative protection provided by SUNSCREENING AGENTS against burns due to ultraviolet (UV) radiation from a light source.alpha-Amylases: Enzymes that catalyze the endohydrolysis of 1,4-alpha-glycosidic linkages in STARCH; GLYCOGEN; and related POLYSACCHARIDES and OLIGOSACCHARIDES containing 3 or more 1,4-alpha-linked D-glucose units.Myristates: Salts and esters of the 14-carbon saturated monocarboxylic acid--myristic acid.Glucan 1,4-alpha-Glucosidase: An enzyme that catalyzes the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of polysaccharide chains with the release of beta-glucose. It is also able to hydrolyze 1,6-alpha-glucosidic bonds when the next bond in sequence is 1,4.Drug Stability: The chemical and physical integrity of a pharmaceutical product.Glucosyltransferases: Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor molecule which is frequently another carbohydrate. EC 2.4.1.-.Acarbose: An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE.Drug Carriers: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.Glycoside HydrolasesSolutions: The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)alpha 1-Antitrypsin: Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.Hydrophobic and Hydrophilic Interactions: The thermodynamic interaction between a substance and WATER.Drug Compounding: The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)Spectrometry, Mass, Fast Atom Bombardment: A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.Calorimetry, Differential Scanning: Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.Magnetic Resonance Spectroscopy: Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Kinetics: The rate dynamics in chemical or physical systems.Bacillus: A genus of BACILLACEAE that are spore-forming, rod-shaped cells. Most species are saprophytic soil forms with only a few species being pathogenic.Abbreviations as Topic: Shortened forms of written words or phrases used for brevity.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)beta-Amylase: An enzyme that catalyzes the hydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides so as to remove successive beta-maltose units from the non-reducing ends of the chains. EC 3.2.1.2.Pancreatic alpha-Amylases: A subclass of alpha-amylase ISOENZYMES that are secreted into PANCREATIC JUICE.Crystallization: The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Crystallography, X-Ray: The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Thermoactinomyces: A genus of gram-positive bacteria in the family Thermoactinomycetaceae, that can cause FARMER'S LUNG.Farmer's Lung: A form of alveolitis or pneumonitis due to an acquired hypersensitivity to inhaled antigens associated with farm environment. Antigens in the farm dust are commonly from bacteria actinomycetes (SACCHAROPOLYSPORA and THERMOACTINOMYCES), fungi, and animal proteins in the soil, straw, crops, pelts, serum, and excreta.Actinomycetales: An order of gram-positive, primarily aerobic BACTERIA that tend to form branching filaments.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.DimethylformamideNanofibers: Submicron-sized fibers with diameters typically between 50 and 500 nanometers. The very small dimension of these fibers can generate a high surface area to volume ratio, which makes them potential candidates for various biomedical and other applications.Formamides: A group of amides with the general formula of R-CONH2.Organic Chemistry Phenomena: The conformation, properties, reaction processes, and the properties of the reactions of carbon compounds.ArchivesSendai virus: The type species of RESPIROVIRUS in the subfamily PARAMYXOVIRINAE. It is the murine version of HUMAN PARAINFLUENZA VIRUS 1, distinguished by host range.Parainfluenza Virus 1, Human: A species of RESPIROVIRUS also called hemadsorption virus 2 (HA2), which causes laryngotracheitis in humans, especially children.Respirovirus: A genus of the family PARAMYXOVIRIDAE (subfamily PARAMYXOVIRINAE) where all the virions have both HEMAGGLUTININ and NEURAMINIDASE activities and encode a non-structural C protein. SENDAI VIRUS is the type species.Virology: The study of the structure, growth, function, genetics, and reproduction of viruses, and VIRUS DISEASES.Perfume: A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell, especially a fluid containing fragrant natural oils extracted from flowers, woods, etc., or similar synthetic oils. (Random House Unabridged Dictionary, 2d ed)Water SofteningTextiles

Properties of a cyclodextrin-specific, unusual porin from Klebsiella oxytoca. (1/76)

The function of CymA, 1 of the 10 gene products involved in cyclodextrin uptake and metabolism by Klebsiella oxytoca, was characterized. CymA is essential for growth on cyclodextrins, but it can also complement the deficiency of a lamB (maltoporin) mutant of Escherichia coli for growth on linear maltodextrins, indicating that both cyclic and linear oligosaccharides are accepted as substrates. CymA was overproduced in E. coli and purified to apparent homogeneity. CymA is a component of the outer membrane, is processed from a signal peptide-containing precursor, and possesses a high content of antiparallel beta-sheet. Incorporation of CymA into lipid bilayers and conductance measurements revealed that it forms ion-permeable channels, which exhibit a substantial current noise. CymA-induced membrane conductance decreased considerably upon addition of alpha-cyclodextrin. Titration experiments allowed the calculation of a half-saturation constant, K(S), of 28 microM for its binding to CymA. CymA assembled in vitro to two-dimensionally crystalline tubular membranes, which, on electron microscopy, are characterized by a p1-related two-sided plane group. The crystallographic unit cell contains four monomeric CymA molecules showing a central pore. The lattice parameters are a = 16.1 nm, b = 3.8 nm, gamma = 93 degrees. CymA does not form trimeric complexes in lipid membranes and shows no tendency to trimerize in solution. CymA thus is an atypical porin with novel properties specialized to transfer cyclodextrins across the outer membrane.  (+info)

Enzymatic synthesis of N-acetylglucosaminyl-cyclodextrin by the reverse reaction of N-acetylhexosaminidase from jack bean. (2/76)

Novel heterobranched cyclodextrins (CDs), N-acetylglucosaminyl-cyclodextrins (GlcNAc-CD), were synthesized from a mixture of GlcNAc and alpha, beta, or gamma CD by the reverse reaction of N-acetylhexosaminidase from jack bean. Optimum pH and temperature for the production of GlcNAc-alpha CD by N-acetylhexosaminidase were pH 4.9 and 50-70 degrees C, respectively. The maximum yield of GlcNAc-alpha CD was 17.5% (mol/mol) at the concentration of 1 M GlcNAc and 0.25 M alpha CD. The reverse reaction product, GlcNAc-alpha CD, was separated into two peaks by HPLC analysis on the ODS column. Their structures were identified as 6-O-beta-D-N-acetylglucosaminyl-alpha CD and 2-O-beta-D-N-acetylglucosaminyl-alpha CD by FAB-MS and NMR spectroscopies. N-Acetylhexosaminidase from jack bean also synthesized N-acetylgalactosaminyl-alpha CD from N-acetylgalactosamine and alpha CD.  (+info)

Probing protein-sugar interactions. (3/76)

We have investigated the partial specific volumes (2) (ml/g), hydration, and cosolvent interactions of rabbit muscle aldolase by equilibrium sedimentation in the analytical ultracentrifuge and by direct density increment (partial differential/partial differentialc(2))(mu) measurements over a range of sugar concentrations and temperature. In a series of sugars increasing in size, glucose, sucrose, raffinose, and alpha-cyclodextrin, (partial differential/ partial differentialc(2))(mu) decreases linearly with the solvent density rho(0). These sugar cosolvents do not interact with the protein; however, the interaction parameter B(1) (g water/g protein) mildly increases with increasing sugar size. The experimental B(1) values are smaller than values calculated by excluded volume (rolling ball) considerations. B(1) relates to hydration in this and in other instances studied. It decreases with increasing temperature, leading to an increase in (2) due to reduced water of hydration electrostriction. The density increments (partial differential/ partial differentialc(2))(mu), however, decrease in concave up form in the case of glycerol and in concave down form for trehalose, leading to more complex behavior in the case of carbohydrates playing a biological role as osmolytes and antifreeze agents. A critical discussion, based on the thermodynamics of multicomponent solutions, is presented.  (+info)

alpha-cyclodextrin extracts diacylglycerol from insect high density lipoproteins. (4/76)

alpha-Cyclodextrins are water-soluble cyclic hexamers of glucose units with hydrophobic cavities capable of solubilizing lipophiles. Incubating alpha-cyclodextrin with high density lipophorin from Manduca sexta or Bombyx mori resulted in a cloudy, turbid solution. Centrifugation separated a pale yellowish precipitate. Thin-layer chromatography analysis of the lipid extract of the precipitate showed that the major lipid was diacylglycerol, while KBr density gradient analysis of the supernatant demonstrated the presence of a lipid-depleted very high density lipophorin. Transfer of diacylglycerol from lipophorin to cyclodextrin was specific to alpha-cyclodextrin and was not observed with beta- or gamma-cyclodextrins. pH had no effect on diacylglycerol transfer to alpha-cyclodextrin. However, the transfer was strongly dependent on the concentration of alpha-cyclodextrin and temperature. Increasing the concentration of alpha-cyclodextrin in the incubation mixture was associated with the formation of increasingly higher density lipophorins. Thus, at 20, 30, and 40 mm alpha-cyclodextrin, the density of B. mori lipophorin increased from 1.107 g/ml to 1.123, 1. 148, and 1.181 g/ml, respectively. At concentrations greater than 40 mm, alpha-cyclodextrin had no further effect on the density of lipophorin. alpha-Cyclodextrin removed at most 83;-87% of the diacylglycerol present in lipophorin. Temperature played an important role in altering the amount of diacylglycerols transferred to alpha-cyclodextrin. At 30 mm alpha-cyclodextrin, the amount of diacylglycerol transferred at different temperatures was 50% at 4 degrees C, 41% at 15 degrees C, 20% at 28 degrees C, and less than 3% at 37 degrees C. We propose that diacylglycerol transfers to alpha-cyclodextrin via an aqueous diffusion pathway and that the driving force for the transfer is the formation of an insoluble alpha-cyclodextrin-diacylglycerol complex.  (+info)

Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying. (5/76)

The taste and flavor of spray-dried powdered products are the most important quality factors. In the present study, molecular encapsulation in cyclodextrin was applied to prevent the loss of a hydrophobic flavor compound (l-menthol) during the drying of a droplet. beta-Cyclodextrin appeared to be a better encapsulant for menthol than alpha- and gamma-cyclodextrin. The retention of menthol increased with increasing concentration of both cyclodextrin and maltodextrin. A simple mathematical model is proposed for estimating the flavor retention. The theoretical results by this model estimated well the final retention of menthol encapsulated in a blend of beta-cyclodextrin and maltodextrin.  (+info)

Mechanism of porcine pancreatic alpha-amylase. Inhibition of amylose and maltopentaose hydrolysis by alpha-, beta- and gamma-cyclodextrins. (6/76)

The effects of alpha-, beta- and gamma-cyclodextrins on the amylose and maltopentaose hydrolysis catalysed by porcine pancreatic alpha-amylase (PPA) were investigated. The results of the statistical analysis performed on the kinetic data using the general initial velocity equation of a one-substrate reaction in the presence of one inhibitor indicate that the type of inhibition involved depends on the substrate used: the inhibition of amylose hydrolysis by alpha-, beta- and gamma-cyclodextrin is of the competitive type, while the inhibition of maltopentaose hydrolysis is of the mixed noncompetitive type. Consistently, the Lineweaver-Burk plots intersect on the vertical axis when amylose is used as the substrate, while in the case of maltopentaose, the intersection occurs at a point located in the second quadrant. The inhibition of the hydrolysis therefore involves only one abortive complex, PPA-cyclodextrin, when amylose is used as the substrate, while two abortive complexes, PPA-cyclodextrin and PPA-maltopentaose-cyclodextrin, are involved with maltopentaose. The mixed noncompetitive inhibition thus shows the existence of one accessory binding site. In any case, only one molecule of inhibitor binds to PPA. In line with these findings, the difference spectra of PPA produced by alpha-, beta- and gamma-cyclodextrin indicate that binding occurs at a tryptophan and a tyrosine residue. The corresponding dissociation constants and the inhibition constants obtained using the kinetic approach are in the same range (1.2-7 mM). The results obtained here on the inhibition of maltopentaose hydrolysis by cyclodextrin are similar to those previously obtained with acarbose as the inhibitor [Alkazaz, M., Desseaux, V., Marchis-Mouren, G., Prodanov, E. & Santimone, M. (1998) Eur. J. Biochem. 252, 100-107], but differ from those obtained with amylose as the substrate and acarbose as inhibitor [Alkazaz, M., Desseaux, V., Marchis-Mouren, G., Payan, F., Forest, E. & Santimone, M. (1996) Eur. J. Biochem. 241, 787-796]. It is concluded that the hydrolysis of both long and short chain substrates requires at least one secondary binding site, including a tryptophan residue.  (+info)

Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media. (7/76)

Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with a- and /-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-beta-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 x 10(5) mol(-2) l(2) was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.  (+info)

Pharmacokinetics and pharmacodynamics of human chorionic gonadotropin (hCG) after rectal administration of hollow-type suppositories containing hCG. (8/76)

To determine the effectiveness of human chorionic gonadotropin (hCG) administered rectally, we studied the pharmacokinetics and pharmacodynamics of hCG using a hollow-type suppository. HCG was not detected in plasma when only hCG was administered rectally, even at a higher dose (4,000 IU/kg body weight) than intravenous injection, because of its low bioavailability due to high molecular weight or degradation by proteolytic activity. To enhance the rectal absorption of hCG, the effectiveness of its coadministration with alpha-cyclodextrin (alpha-CyD), an absorption-enhancing agent, was investigated in male rabbits. HCG was detected in plasma following coadministration of hCG and alpha-CyD (10 mg/kg body weight) into the rectum. The plasma hCG concentration increased with increasing dose of alpha-CyD. The AUC(0-48) observed after coadministration of hCG and alpha-CyD at 30 mg/kg body weight was approximately four times higher than that of hCG and alpha-CyD at 10mg/kg body weight. HCG at a high concentration induced a rapid increase in the plasma testosterone concentration (74.2 +/- 3.4 ng/ml) 2 h after intravenous administration. However, the testosterone concentration 24 h after intravenous administration decreased to the physiological level (approximately 20 ng/ml) which had been observed before such administration. On the other hand, the maximum level of testosterone concentration (40.0 +/- 12.6 ng/ml) was observed 24 h after rectal administration of hCG (400 IU/kg body weight) in combination with alpha-CyD (30 mg/kg body weight). Moreover, the plasma testosterone concentration (31.0 +/- 11.4 ng/ml) obtained 72 h after rectal administration tended to be maintained at a higher level than that (14.4 +/- 0.9ng/ml) observed before the administration. These results suggest that the hollow-type suppository as a rectal delivery system of hCG is promising as a new mode of hCG therapy.  (+info)

  • full citation needed][full citation needed] α-Cyclodextrin is a multifunctional, soluble dietary fiber marketed for use as a fiber ingredient, an odor or flavor masking agent as well as for emulsification applications. (wikipedia.org)
  • full citation needed] According to these authors, the number of cyclodextrin molecules per fatty acid appears to be dependent upon the length of the fatty acids that are involved. (wikipedia.org)
  • Unlike lipase inhibitors, alpha-cyclodextrin forms a stable complex with the dietary fat which prevents lipase from digesting the triglyceride and the normal gut flora from using it as a carbon source, thus preventing the side effects of the lipase inhibitors. (wikipedia.org)
  • α-Cyclodextrin is marketed for a range of medical, healthcare and food and beverage applications which rely on its ability to bind to fats and reduce their bioavailability both in the body and in food and beverage products. (wikipedia.org)
  • α-Cyclodextrin has the unique ability among known fibers to bind nine times its own weight in fat. (wikipedia.org)
  • Although many dietary fibers appear to bind fat on a 1:1 ratio α-cyclodextrin is the only one that binds on a 1:9 (fiber:fat) ratio. (wikipedia.org)
  • Lower blood (LDL or bad) low-density lipoprotein cholesterol levels Lower blood triglyceride levels Preferentially lowers blood saturated fat and trans fat levels Increased insulin sensitivity Increased leptin sensitivity - increased satiety[full citation needed] Improved glycemic index of foods and improved glycemic control Due to its surface active properties, α-cyclodextrin can also be used as an emulsifying fiber, for example in mayonnaise. (wikipedia.org)
  • As the molecular weight of the fiber and triglycerides are about the same, it would appear to follow that the cyclodextrin is actually forming a layer on the surface of the fat droplets. (wikipedia.org)
  • Alpha-Fibe is the original product that contains this unique fiber, introduced to the worldwide nutritional supplement market by Bio-Form Essentials in 2007. (wikipedia.org)
  • have demonstrated that α-cyclodextrin and soybean oil can form porous beads that may find utility in delivering water-insoluble pharmaceuticals. (wikipedia.org)
  • have demonstrated that at an oil:water interface α-cyclodextrin "threads" onto fatty acids in a manner analogous to threading beads onto a string. (wikipedia.org)
  • for example, demonstrated that α-cyclodextrin was very effective at solubilizing the free fatty acids that are generated in the colorimetric determination of triglycerides. (wikipedia.org)
  • There are two other naturally occurring cyclodextrins, β (beta) - and γ (gamma) -, which contain seven and eight glucose units respectively. (wikipedia.org)
  • Structure and thermodynamics of alpha-, beta-, and gamma-cyclodextrin dimers. (eurekamag.com)
  • The alpha-, beta-, and gamma-cyclodextrin (CyDs) dimers were studied by molecular dynamics (MD) simulations in water as an explicit solvent. (eurekamag.com)
  • In a vacuum, MD simulations provided the head-to-head orientation as the most stable orientation for the three CyDs, while in aqueous solution the, the head-to-tail orientation was found to be the most stable for the alpha-CyD dimer and the tail-to-tail orientation the most stable for the beta- and gamma-CyD dimers. (eurekamag.com)
  • Alpha-, beta-, and gamma-cyclodextrin are all generally recognized as safe by the FDA. (wikipedia.org)
  • The importance of considering gamma-tocopherol in human nutrition is underscored by reports that supplementation with alpha-tocopherol in doses of 200-1,200 IU per day decreased serum levels of gamma-tocopherol by accelerating its metabolism. (thefreedictionary.com)
  • When added to wormlike micelles of ChEO(10) and C12EO3, native beta-CD, 2-hydroxyethyl-beta-CD (HEBCD), and a sulfated sodium salt of beta-CD (SULFBCD) induce a substantial increase of the viscoelasticity, while methylated CDs rupture the micelles, leading to a loss of the viscosity, and the other CDs studied (native alpha- and gamma- and hydroxypropylated CDs) show a weak interaction. (diva-portal.org)
  • The strong ability of complexing fragrances can also be used for another purpose: first dry, solid cyclodextrin microparticles are exposed to a controlled contact with fumes of active compounds, then they are added to fabric or paper products. (wikipedia.org)
  • 2) Mono-[6-(1-pyridinio)-6-deoxy]-cyclodextrin was immobilized on bridge type or pendant type polymers, and the adsorption of the nitrate ion on the host polymers was examined in an aqueous solution. (nii.ac.jp)
  • 3) All the C(6)-OH groups of cyclodextrins were replaced with butylamino groups, and an ability of the resulting hosts to bind the nitrate ion was examined in an acidic aqueous solution. (nii.ac.jp)
  • Absorption, distribution, and excretion -cyclodextrin is resistant to hydrolysis by acid (Szeftli & Budai, 1976), alpha- and -amylases and yeast. (inchem.org)
  • 1985). The intestinal absorption, digestibility by the colonic microflora, and urinary excretion of -cyclodextrin were studied. (inchem.org)
  • Unlike lipase inhibitors, alpha-cyclodextrin forms a stable complex with the dietary fat which prevents lipase from digesting the triglyceride and the normal gut flora from using it as a carbon source, thus preventing the side effects of the lipase inhibitors. (wikipedia.org)
  • Towards porous silica materials via nanocasting of stable pseudopolyrotaxanes from alpha-cyclodextrin and polyamines. (mpg.de)
  • A0A0U3SAD4_9EURY Glycoside hydrolase 57 family enzyme, alpha-amylase/4alpha-gluconotranspherase, putative OS=Thermococcus sp. (uniprot.org)
  • Supramolecular polymers with monomers bound together by secondary interactions, such as polyrotaxanes (PRXs), consisting of alpha cyclodextrin (αCD) threaded onto poly(ethylene glycol) (PEG), have attracted interest as a result of their ability to overcome physical limitations present in conventional, covalently structured polymers. (rsc.org)
  • demonstrated that α-cyclodextrin could complex triglyceride and at ratios that are significantly different from the 1:1 that is typical for dietary fibers. (wikipedia.org)
  • These structures give evidence for substrate distortion and the covalent character of the intermediate and for the first time show, in atomic detail, how catalysis in the alpha-amylase family proceeds by the concerted action of all active site residues. (ubc.ca)
Feasibility Studies: Alpha-Cyclodextrin Manufacturing - English
Feasibility Studies: Alpha-Cyclodextrin Manufacturing - English (slideshare.net)
Maria Lucia Curri | Consiglio Nazionale delle Ricerche
Maria Lucia Curri | Consiglio Nazionale delle Ricerche (cnr.it)
Get PDF - Structure and thermodynamics of alpha-, beta-, and gamma-cyclodextrin dimers. Molecular dynamics studies of the...
Get PDF - Structure and thermodynamics of alpha-, beta-, and gamma-cyclodextrin dimers. Molecular dynamics studies of the... (eurekamag.com)
Quiz Pregpat 1 - ProProfs Quiz
Quiz Pregpat 1 - ProProfs Quiz (proprofs.com)
RCSB PDB - 1BYC: CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND...
RCSB PDB - 1BYC: CRYSTAL STRUCTURES OF SOYBEAN BETA-AMYLASE REACTED WITH BETA-MALTOSE AND MALTAL: ACTIVE SITE COMPONENTS AND... (rcsb.org)
Neuroblastoma | GreenMedInfo | Disease | Natural Medicine
Neuroblastoma | GreenMedInfo | Disease | Natural Medicine (greenmedinfo.com)
Octanedioic acid, dimethyl ester
Octanedioic acid, dimethyl ester (webbook.nist.gov)
Medical Foods: Opportunities In An Emerging Market - Nutraceuticals World
Medical Foods: Opportunities In An Emerging Market - Nutraceuticals World (nutraceuticalsworld.com)
Instituto de Biotecnologia UNAM
Instituto de Biotecnologia UNAM (ibt.unam.mx)
Supramolecular Interaction of Primaquine with Native β-Cyclodextrin, Journal of Solution Chemistry | 10.1007/s10953-018-0768-2 ...
Supramolecular Interaction of Primaquine with Native β-Cyclodextrin, Journal of Solution Chemistry | 10.1007/s10953-018-0768-2 ... (deepdyve.com)
Francisco Mendicuti Madrid
Francisco Mendicuti Madrid (uah.es)
Iterative Saturation Mutagenesis of −6 Subsite Residues in Cyclodextrin Glycosyltransferase from Paenibacillus macerans To...
Iterative Saturation Mutagenesis of −6 Subsite Residues in Cyclodextrin Glycosyltransferase from Paenibacillus macerans To... (aem.asm.org)
Block Fat Absorption to Lose Weight with FBCx - eVitamins México
Block Fat Absorption to Lose Weight with FBCx - eVitamins México (evitamins.com)
Boost your metabolism AND the microbiota in your colon with a small amount of prebiotics - NaturalNews.com
Boost your metabolism AND the microbiota in your colon with a small amount of prebiotics - NaturalNews.com (naturalnews.com)
Surface-Modified Conducting Polymer-Based Nanostructured Materials for the Removal of Toxic Heavy Metals from Wastewater |...
Surface-Modified Conducting Polymer-Based Nanostructured Materials for the Removal of Toxic Heavy Metals from Wastewater |... (link.springer.com)
Caverject (Alprostadil Injection): Side Effects, Interactions, Warning, Dosage & Uses
Caverject (Alprostadil Injection): Side Effects, Interactions, Warning, Dosage & Uses (rxlist.com)
Siril Skaret Bakke - NTNU
Siril Skaret Bakke - NTNU (ntnu.edu)
CycloMolder software: building theoretical cyclodextrin derivatives models and evaluating their host:guest interactions |...
CycloMolder software: building theoretical cyclodextrin derivatives models and evaluating their host:guest interactions |... (link.springer.com)
Enabling Healthy Living - Wacker Chemie AG
Enabling Healthy Living - Wacker Chemie AG (wacker.com)
Wissenschaftliche Publikationen des Instituts | Max-Planck-Institut für Kolloid- und Grenzflächenforschung
Wissenschaftliche Publikationen des Instituts | Max-Planck-Institut für Kolloid- und Grenzflächenforschung (mpikg.mpg.de)
The Chia Co Launches New Chia Pods & Oats+Chia Varieties - Nutraceuticals World
The Chia Co Launches New Chia Pods & Oats+Chia Varieties - Nutraceuticals World (nutraceuticalsworld.com)
Two Novel, Putatively Cell Wall-Associated and Glycosylphosphatidylinositol-Anchored α-Glucanotransferase Enzymes of...
Two Novel, Putatively Cell Wall-Associated and Glycosylphosphatidylinositol-Anchored α-Glucanotransferase Enzymes of... (ec.asm.org)
FDA Responds to Three Dietary Fiber Citizen Petitions - Lexology
FDA Responds to Three Dietary Fiber Citizen Petitions - Lexology (lexology.com)
Condensed conifer tannins as antifungal agents in liquid culture : Holzforschung
Condensed conifer tannins as antifungal agents in liquid culture : Holzforschung (degruyter.com)
Application # 2017/0363577. FORMATION OF LAYERS OF AMPHIPHILIC MOLECULES - Patents.com
Application # 2017/0363577. FORMATION OF LAYERS OF AMPHIPHILIC MOLECULES - Patents.com (patents.com)
Omega 3-Tocotrienol Combination Supplement - Nutraceuticals World
Omega 3-Tocotrienol Combination Supplement - Nutraceuticals World (nutraceuticalsworld.com)
Adsorption of CO2 on amine-functionalized green metal-organic framework: an interaction between amine and CO2 molecules |...
Adsorption of CO2 on amine-functionalized green metal-organic framework: an interaction between amine and CO2 molecules |... (link.springer.com)
Lipexa FBCx prebiotic fiber - Klaire Labs
Lipexa FBCx prebiotic fiber - Klaire Labs (klaire.com)
Tapping into veganism: Wacker presents vegan concepts at Fi Europe 2019
Tapping into veganism: Wacker presents vegan concepts at Fi Europe 2019 (foodingredientsfirst.com)
Quantitative and qualitative analyses of intermolecular interactions in neutral/deprotonated aspirin@β-CD inclusion complexes:...
Quantitative and qualitative analyses of intermolecular interactions in neutral/deprotonated [email protected]β-CD inclusion complexes:... (link.springer.com)