OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
AmanitaAmanitinsMushroom PoisoningAlpha-AmanitinRNA Polymerase IIalpha 1-AntitrypsinReceptors, Adrenergic, alphaHypoxia-Inducible Factor 1, alpha Subunitalpha7 Nicotinic Acetylcholine ReceptorIntegrin alpha3beta1Integrin alpha4Integrin alpha6Integrin alpha5beta1Integrin alpha4beta1Interleukin-1alphaIntegrin alpha2beta1Receptors, Adrenergic, alpha-1Integrin alpha5Integrin alpha1beta1Receptors, Adrenergic, alpha-2Integrin alpha6beta1Base SequenceIntegrin alpha6beta4Integrin alpha ChainsIntegrinsIntegrin alpha1Alpha RhythmIntegrin alpha3alpha 1-Antitrypsin DeficiencyProtein BindingMolecular Sequence DataReceptors, NicotinicAdrenergic alpha-Agonists
Amanita
A genus of fungi of the family Agaricaceae, order Agaricales; most species are poisonous.
Amanitins
Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species, blocking the production of mRNA and protein synthesis. These peptides are important in the study of transcription. Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals.
Mushroom Poisoning
Poisoning from ingestion of mushrooms, primarily from, but not restricted to, toxic varieties.
Alpha-Amanitin
A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. It inhibits RNA POLYMERASE II. Poisoning may require LIVER TRANSPLANTATION.
RNA Polymerase II
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
alpha 1-Antitrypsin
Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.
Receptors, Adrenergic, alpha
One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
Hypoxia-Inducible Factor 1, alpha Subunit
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted for degradation by VHL TUMOR SUPPRESSOR PROTEIN.
alpha7 Nicotinic Acetylcholine Receptor
A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric a7 subunits expressed in the CNS, autonomic nervous system, vascular system, lymphocytes and spleen.
Integrin alpha3beta1
Cell surface receptor for LAMININ, epiligrin, FIBRONECTINS, entactin, and COLLAGEN. Integrin alpha3beta1 is the major integrin present in EPITHELIAL CELLS, where it plays a role in the assembly of BASEMENT MEMBRANE as well as in cell migration, and may regulate the functions of other integrins. Two alternatively spliced isoforms of the alpha subunit (INTEGRIN ALPHA3), are differentially expressed in different cell types.
Integrin alpha4
An integrin alpha subunit that is unique in that it does not contain an I domain, and its proteolytic cleavage site is near the middle of the extracellular portion of the polypeptide rather than close to the membrane as in other integrin alpha subunits.
Integrin alpha6
An integrin alpha subunit that primarily associates with INTEGRIN BETA1 or INTEGRIN BETA4 to form laminin-binding heterodimers. Integrin alpha6 has two alternatively spliced isoforms: integrin alpha6A and integrin alpha6B, which differ in their cytoplasmic domains and are regulated in a tissue-specific and developmental stage-specific manner.
Integrin alpha5beta1
An integrin found in FIBROBLASTS; PLATELETS; MONOCYTES, and LYMPHOCYTES. Integrin alpha5beta1 is the classical receptor for FIBRONECTIN, but it also functions as a receptor for LAMININ and several other EXTRACELLULAR MATRIX PROTEINS.
Integrin alpha4beta1
Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.
Interleukin-1alpha
An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.
Integrin alpha2beta1
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.
Receptors, Adrenergic, alpha-1
A subclass of alpha-adrenergic receptors that mediate contraction of SMOOTH MUSCLE in a variety of tissues such as ARTERIOLES; VEINS; and the UTERUS. They are usually found on postsynaptic membranes and signal through GQ-G11 G-PROTEINS.
Integrin alpha5
This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
Integrin alpha1beta1
Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed during development, but in the adult is the predominant laminin receptor (RECEPTORS, LAMININ) in mature SMOOTH MUSCLE CELLS, where it is important for maintenance of the differentiated phenotype of these cells. Integrin alpha1beta1 is also found in LYMPHOCYTES and microvascular endothelial cells, and may play a role in angiogenesis. In SCHWANN CELLS and neural crest cells, it is involved in cell migration. Integrin alpha1beta1 is also known as VLA-1 and CD49a-CD29.
Receptors, Adrenergic, alpha-2
A subclass of alpha-adrenergic receptors found on both presynaptic and postsynaptic membranes where they signal through Gi-Go G-PROTEINS. While postsynaptic alpha-2 receptors play a traditional role in mediating the effects of ADRENERGIC AGONISTS, the subset of alpha-2 receptors found on presynaptic membranes signal the feedback inhibition of NEUROTRANSMITTER release.
Integrin alpha6beta1
A cell surface receptor mediating cell adhesion to the EXTRACELLULAR MATRIX and to other cells via binding to LAMININ. It is involved in cell migration, embryonic development, leukocyte activation and tumor cell invasiveness. Integrin alpha6beta1 is the major laminin receptor on PLATELETS; LEUKOCYTES; and many EPITHELIAL CELLS, and ligand binding may activate a number of signal transduction pathways. Alternative splicing of the cytoplasmic domain of the alpha6 subunit (INTEGRIN ALPHA6) results in the formation of A and B isoforms of the heterodimer, which are expressed in a tissue-specific manner.
Base Sequence
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Integrin alpha6beta4
This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
Integrin alpha Chains
The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4.
Integrins
A family of transmembrane glycoproteins (MEMBRANE GLYCOPROTEINS) consisting of noncovalent heterodimers. They interact with a wide variety of ligands including EXTRACELLULAR MATRIX PROTEINS; COMPLEMENT, and other cells, while their intracellular domains interact with the CYTOSKELETON. The integrins consist of at least three identified families: the cytoadhesin receptors(RECEPTORS, CYTOADHESIN), the leukocyte adhesion receptors (RECEPTORS, LEUKOCYTE ADHESION), and the VERY LATE ANTIGEN RECEPTORS. Each family contains a common beta-subunit (INTEGRIN BETA CHAINS) combined with one or more distinct alpha-subunits (INTEGRIN ALPHA CHAINS). These receptors participate in cell-matrix and cell-cell adhesion in many physiologically important processes, including embryological development; HEMOSTASIS; THROMBOSIS; WOUND HEALING; immune and nonimmune defense mechanisms; and oncogenic transformation.
Integrin alpha1
An integrin alpha subunit that binds COLLAGEN and LAMININ though its I domain. It combines with INTEGRIN BETA1 to form the heterodimer INTEGRIN ALPHA1BETA1.
Alpha Rhythm
Brain waves characterized by a relatively high voltage or amplitude and a frequency of 8-13 Hz. They constitute the majority of waves recorded by EEG registering the activity of the parietal and occipital lobes when the individual is awake, but relaxed with the eyes closed.
Integrin alpha3
An integrin alpha subunit that occurs as alternatively spliced isoforms. The isoforms are differentially expressed in specific cell types and at specific developmental stages. Integrin alpha3 combines with INTEGRIN BETA1 to form INTEGRIN ALPHA3BETA1 which is a heterodimer found primarily in epithelial cells.
alpha 1-Antitrypsin Deficiency
Deficiency of the protease inhibitor ALPHA 1-ANTITRYPSIN that manifests primarily as PULMONARY EMPHYSEMA and LIVER CIRRHOSIS.
Protein Binding
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Receptors, Nicotinic
One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
Adrenergic alpha-Agonists
Drugs that selectively bind to and activate alpha adrenergic receptors.

A tunable ratchet driving human RNA polymerase II translocation adjusted by accurately templated nucleoside triphosphates loaded at downstream sites and by elongation factors. (1/38)

When nucleoside triphosphate (NTP) substrates and alpha-amanitin are added to a human RNA polymerase II elongation complex simultaneously, the reaction becomes stalled in the core of the bond synthesis mechanism. The mode of stalling is influenced by NTP substrates at the active site and at downstream sites and by transcription factor IIF (TFIIF) and TFIIS. NTP substrates templated at i+2, i+3, and i+4 downstream DNA sites can reverse the previously stable binding of an NTP loaded at the i+1 substrate site. Deoxy-(d)NTPs and NDPs (nucleoside diphosphates) do not substitute for NTPs at the i+2 and i+3 positions (considered together) or the i+4, i+5, and i+6 positions (considered together). The mode of stalling is altered by changing the number of downstream template sites that are accurately occupied by NTPs and by changing NTP concentration. In the presence of the translocation blocker alpha-amanitin, a steady state condition is established in which RNA polymerase II stably loads an NTP substrate at i+1 and forms a phosphodiester bond but cannot rapidly complete bond synthesis by releasing pyrophosphate. These observations support a role for incoming NTP substrates in stimulating translocation; results appear inconsistent with the secondary pore being the sole route of NTP entry for human RNA polymerase II, and results indicate mechanisms of dynamic error avoidance and error correction during rapid RNA synthesis.  (+info)

Nucleolar translocalization of GRA10 of Toxoplasma gondii transfectionally expressed in HeLa cells. (2/38)

Toxoplasma gondii GRA10 expressed as a GFP-GRA10 fusion protein in HeLa cells moved to the nucleoli within the nucleus rapidly and entirely. GRA10 was concentrated specifically in the dense fibrillar component of the nucleolus morphologically by the overlap of GFP-GRA10 transfection image with IFA images by monoclonal antibodies against GRA10 (Tg378), B23 (nucleophosmin) and C23 (nucleolin). The nucleolar translocalization of GRA10 was caused by a putative nucleolar localizing sequence (NoLS) of GRA10. Interaction of GRA10 with TATA-binding protein associated factor 1B (TAF1B) in the yeast two-hybrid technique was confirmed by GST pull-down assay and immunoprecipitation assay. GRA10 and TAF1B were also co-localized in the nucleolus after co-transfection. The nucleolar condensation of GRA10 was affected by actinomycin D. Expressed GFP-GRA10 was evenly distributed over the nucleoplasm and the nucleolar locations remained as hollows in the nucleoplasm under a low dose of actinomycin D. Nucleolar localizing and interacting of GRA10 with TAF1B suggested the participation of GRA10 in rRNA synthesis of host cells to favor the parasitism of T. gondii.  (+info)

RNA is an integral component of chromatin that contributes to its structural organization. (3/38)

Chromatin structure is influenced by multiples factors, such as pH, temperature, nature and concentration of counterions, post-translational modifications of histones and binding of structural non-histone proteins. RNA is also known to contribute to the regulation of chromatin structure as chromatin-induced gene silencing was shown to depend on the RNAi machinery in S. pombe, plants and Drosophila. Moreover, both in Drosophila and mammals, dosage compensation requires the contribution of specific non-coding RNAs. However, whether RNA itself plays a direct structural role in chromatin is not known. Here, we report results that indicate a general structural role for RNA in eukaryotic chromatin. RNA is found associated to purified chromatin prepared from chicken liver, or cultured Drosophila S2 cells, and treatment with RNase A alters the structural properties of chromatin. Our results indicate that chromatin-associated RNAs, which account for 2%-5% of total chromatin-associated nucleic acids, are polyA(-) and show a size similar to that of the DNA contained in the corresponding chromatin fragments. Chromatin-associated RNA(s) are not likely to correspond to nascent transcripts as they are also found bound to chromatin when cells are treated with alpha-amanitin. After treatment with RNase A, chromatin fragments of molecular weight >3.000 bp of DNA showed reduced sedimentation through sucrose gradients and increased sensitivity to micrococcal nuclease digestion. This structural transition, which is observed both at euchromatic and heterochromatic regions, proceeds without loss of histone H1 or any significant change in core-histone composition and integrity.  (+info)

Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III. (4/38)

Recent genomic data indicate that RNA polymerase II (Pol II) function extends beyond conventional transcription of primarily protein-coding genes. Among the five snRNAs required for pre-mRNA splicing, only the U6 snRNA is synthesized by RNA polymerase III (Pol III). Here we address the question of how Pol II coordinates the expression of spliceosome components, including U6. We used chromatin immunoprecipitation (ChIP) and high-resolution mapping by PCR to localize both Pol II and Pol III to snRNA gene regions. We report the surprising finding that Pol II is highly concentrated approximately 300 bp upstream of all five active human U6 genes in vivo. The U6 snRNA, an essential component of the spliceosome, is synthesized by Pol III, whereas all other spliceosomal snRNAs are Pol II transcripts. Accordingly, U6 transcripts were terminated in a Pol III-specific manner, and Pol III localized to the transcribed gene regions. However, synthesis of both U6 and U2 snRNAs was alpha-amanitin-sensitive, indicating a requirement for Pol II activity in the expression of both snRNAs. Moreover, both Pol II and histone tail acetylation marks were lost from U6 promoters upon alpha-amanitin treatment. The results indicate that Pol II is concentrated at specific genomic regions from which it can regulate Pol III activity by a general mechanism. Consequently, Pol II coordinates expression of all RNA and protein components of the spliceosome.  (+info)

The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin. (5/38)

 (+info)

Resistance of mitochondrial p53 to dominant inhibition. (6/38)

 (+info)

Expression of microRNA processing machinery genes in rhesus monkey oocytes and embryos of different developmental potentials. (7/38)

 (+info)

Identification of a novel pathway that selectively modulates apoptosis of breast cancer cells. (8/38)

 (+info)

troubleshooting - Do the DSLRKIT PT-08XT triggers work with a Vivitar 283 flash and a Sony NEX 6? - Photography Stack Exchangetroubleshooting - Do the DSLRKIT PT-08XT triggers work with a Vivitar 283 flash and a Sony NEX 6? - Photography Stack Exchange
You may have fried the triggers--most of these cheap eBay type triggers have a voltage limit of around 300V, and the Vivitar 283s are known to go higher. So, maybe a voltmeter would be worth the investment. I would also go to the standby advice of check the batteries and the channel settings.. Theoretically, those triggers (which look like theyre for Nikon from the pass-through shoes contact pattern) should work. But if they rely upon a TTL pin signal of some kind, that could be another issue. Its unlikely that this is the case, since those triggers have separate Tx/Rx units, and Ive only see this type of misfunction with the Yongnuo RF-603s (which used a TTL signal to auto switch between Tx/Rx modes, so with non-Canon/Nikon hotshoes, the transmitter unit never went into Tx mode--which is why Yongnuo made an RF-603 II).. Ive seen reports that the Yongnuo RF-603ii triggers work on NEX (and Fuji X and micro four-thirds), but the sync voltage limit is still only 300V (still better than the 11V ...
https://photo.stackexchange.com/questions/38538/do-the-dslrkit-pt-08xt-triggers-work-with-a-vivitar-283-flash-and-a-sony-nex-6
talks.cam : Modelling the transcriptional response to ER signalling in breast cancer cellstalks.cam : Modelling the transcriptional response to ER signalling in breast cancer cells
If you have a question about this talk, please contact Florian Markowetz.. We are developing computational models of transcription and its regulation from high-throughput time course data. I will discuss two models: (1) We model RNA polymerase (pol-II) dynamics using data from pol-II ChIP-Seq time course datasets (wa Maina et al. 2014). Our model is used to estimate the elongation speed and promoter activation kinetics for early targets of ER-alpha in MCF7 cells. By clustering the promoter activation profiles we can associate differences in the kinetics with transcription factor binding, e.g. the earliest clusters are all associated with nearby FOXA1 binding. (2) We model the relationship between pol-II dynamics and mRNA production by combining 3 pol-II ChIP-Seq data with RNA -Seq data. We find that 11% of genes where we can fit our model exhibit surprisingly long production delays which appear to be associated with splicing. Although transcription delays are longer than splicing delays for ...
https://talks.cam.ac.uk/talk/index/53532
ChemIDplus - 55325-99-0 - GBHLBBPUSBXKSA-AGOVMNPFSA-N - alpha-Amanitin, 4-(2-mercapto-6-methoxy-L-tryptophan)-, S-oxide -...ChemIDplus - 55325-99-0 - GBHLBBPUSBXKSA-AGOVMNPFSA-N - alpha-Amanitin, 4-(2-mercapto-6-methoxy-L-tryptophan)-, S-oxide -...
55325-99-0 - GBHLBBPUSBXKSA-AGOVMNPFSA-N - alpha-Amanitin, 4-(2-mercapto-6-methoxy-L-tryptophan)-, S-oxide - Similar structures search, synonyms, formulas, resource links, and other chemical information.
https://chem.nlm.nih.gov/chemidplus/rn/55325-99-0
Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression. - MRC Weatherall...
Spatial/temporal control of Cas9 guide RNA expression could considerably expand the utility of CRISPR-based technologies. Current approaches based on tRNA processing offer a promising strategy but suffer from high background. Here, to address this limitation, we present a screening platform which allows simultaneous measurements of the promoter strength, 5, and 3 processing efficiencies across a library of tRNA variants. This analysis reveals that the sequence determinants underlying these activities, while overlapping, are dissociable. Rational design based on the ensuing principles allowed us to engineer an improved tRNA scaffold that enables highly specific guide RNA production from a Pol-II promoter. When benchmarked against other reported systems this tRNA scaffold is superior to most alternatives, and is equivalent in function to an optimized version of the Csy4-based guide RNA release system. The results and methods described in this manuscript enable avenues of research both in genome
https://www.imm.ox.ac.uk/publications/991313
Galerina marginata - WikipediaGalerina marginata - Wikipedia
Galerina marginata is a species of poisonous fungus in the family Hymenogastraceae of the order Agaricales. Prior to 2001, the species G. autumnalis, G. oregonensis, G. unicolor, and G. venenata were thought to be separate due to differences in habitat and the viscidity of their caps, but phylogenetic analysis showed that they are all the same species. The fruit bodies of this fungus have brown to yellow-brown caps that fade in color when drying. The gills are brownish and give a rusty spore print. A well-defined membranous ring is typically seen on the stems of young specimens but often disappears with age. In older fruit bodies, the caps are flatter and the gills and stems browner. The species is a classic little brown mushroom-a catchall category that includes all small to medium-sized, hard-to-identify brownish mushrooms, and may be easily confused with several edible species. Galerina marginata is widespread in the Northern Hemisphere, including Europe, North America, and Asia, and has ...
https://en.wikipedia.org/wiki/Galerina_marginata
Reaction-based fluorescent sensor for investigating mobile Zn[superscript 2+] in mitochondria of healthy versus cancerous...Reaction-based fluorescent sensor for investigating mobile Zn[superscript 2+] in mitochondria of healthy versus cancerous...
Chelatable, mobile forms of divalent zinc, Zn(II), play essential signaling roles in mammalian biology. A complex network of zinc import and transport proteins has evolved to control zinc concentration and distribution on a subcellular level. Understanding the action of mobile zinc requires tools that can detect changes in Zn(II) concentrations at discrete cellular locales. We present here a zinc-responsive, reaction-based, targetable probe based on the diacetyled form of Zinpyr-1. The compound, (6-amidoethyl)triphenylphosphonium Zinpyr-1 diacetate (DA-ZP1-TPP), is essentially nonfluorescent in the metal-free state; however, exposure to Zn(II) triggers metal-mediated hydrolysis of the acetyl groups to afford a large, rapid, and zinc-induced fluorescence response. DA-ZP1-TPP is insensitive to intracellular esterases over a 2-h period and is impervious to proton-induced turn-on. A TPP unit is appended for targeting mitochondria, as demonstrated by live cell fluorescence imaging studies. The ...
https://dspace.mit.edu/handle/1721.1/89120
View source for Small Molecules for Xenopus Research - Xenbase
Notice to our users== Please help us to improve this small molecules wiki and our other wikis by registering for a wiki account through our normal feedback email. ==Important small molecule references== *[http://www.xenbase.org/literature/article.do?method=display&articleId=35021 Database of Small Molecules by Feldman and Hogue 2006] at [https://pubchem.ncbi.nlm.nih.gov/ PubChem] *[http://www.xenbase.org/literature/article.do?method=display&articleId=47903 Wnt/Notch by Myers and Krieg 2014] *[http://www.xenbase.org/literature/article.do?method=display&articleId=970 Ubiquitin-proteasome by Salic and King 2005] ==Alphabetical List of Small Molecules With Literature References== *[[1,3-Dicyclohexylurea]] *[[11-cis retinal]] *[[18alpha-glycyrretinic acid]] *[[2-deoxyadenosine]] *[[2-APB]] *[[2-Deoxyglucose]] *[[3,3,5-triiodothyronine (T3)]] *[[5HT (seratonin)]] *[[8-Pcpt-2-O-Me-cAMP-AM]] *[[activin]] *[[Adenosine, periodate oxidized]] *[[AG1296]] *[[AG1879]] *[[AGN193109]] *[[alpha-amanitin]] ...
http://wiki.xenbase.org/xenwiki/index.php?title=Small_Molecules_for_Xenopus_Research&action=edit
amanitin | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGYamanitin | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY
The IUPHAR/BPS Guide to Pharmacology. amanitin ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs.
https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=4632
galerina fungi Pictures
Click here for galerina fungi pictures! You can also find pictures of frondosa fungi, geastrum fungi, ganoderma fungi, gallica fungi.
http://www.picsearch.com/galerina-fungi-pictures.html
Dracaena Marginata | House Plants for Delivery- Lively RootDracaena Marginata | House Plants for Delivery- Lively Root
The Dracaena Marginata has a unique silhouette and is perfect for filling in spaces in your garden or Green Space! A perfect houseplant for any room!
https://www.livelyroot.com/products/dracaena-margenata
Lomaspilis marginata | Galerie Entomologique - Nicolas SellierLomaspilis marginata | Galerie Entomologique - Nicolas Sellier
Lomaspilis marginata (Linnaeus, 1758) Bordure entrecoupée (La), Marginée (La) - Lomaspilis marginata-St Hilaire La Pallud-01-05-2014 (6).JPG
https://galeriemacro.nsellier.fr/picture.php/448
Mushroom Poisoning | Harvard Catalyst Profiles | Harvard CatalystMushroom Poisoning | Harvard Catalyst Profiles | Harvard Catalyst
In response to Tong TC, et al. Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model. Ann Emerg Med. 2008 Aug; 52(2):184-5; author reply 185 ...
https://connects.catalyst.harvard.edu/Profiles/display/Concept/Mushroom%20Poisoning
Galerina pumila, Dwarf Bell, a toxic toadstoolGalerina pumila, Dwarf Bell, a toxic toadstool
Galerina pumila, Dwarf Bell, a poisonous mushroom: identification pictures (images), habitat, edible or poisonous; taxonomy, etymology, synonyms, similar species
http://www.first-nature.com/fungi/galerina-pumila.php
Primula marginata ( Marginata Primrose ) | Backyard Gardener
Primula marginata produces, early in the season, umbels of 2 to 20, funnel to tubular shaped, lightly fragrant, lavender-blue flowers, 3/4 inch wide, with white-mealy eyes. This rosette-forming evergreen or semi-evergreen perennial has egg-shaped to oblong, leathery, serrated leaves, to 4 inches long. Primroses like
https://www.backyardgardener.com/plantname/primula-marginata-marginata-primrose/
Glomeris marginata | Semantic ScholarGlomeris marginata | Semantic Scholar
In North Africa, the genus Glomeris is shown to encompass 11 species, all of which are keyed. Th ese include: G. troglokabyliana… Expand ...
https://www.semanticscholar.org/topic/Glomeris-marginata/561419
Explore the ADC component hazards, risks and safety project elements in HPAPIExplore the ADC component hazards, risks and safety project elements in HPAPI
Brief Overview:. SMis global panel of speakers will strengthen your knowledge in key topics such as high potent ingredients, ADC payloads, PK-PD technological advancements, warheads and site selectivity, immune-oncological combination therapies and fragment drug conjugates.. Hear from industry leading pharmaceutical companies and biotechs including Pfizer, Genentech, Seattle Genetics, MedImmune, Janssen, Spirogen and more, who will explore key topics in; new and novel payloads, e.g. Antibody Targeted Amanitin Conjugates (ATACs), principles for maximising the drug delivery efficiency and therapeutic index and using fragment conjugates in order to develop a tailored therapy for solid tumours.. Event Spotlight. The ADC conference will discuss the best ways to approach obstacles faced during different stages of research. While such highly potent compounds can have significant benefits in the treatment of certain medical conditions, they present substantial challenges to the pharmaceutical ...
https://pharmaphorum.com/partner-content/explore-adc-component-hazards-risks-safety-project-elements-hpapi/
inventii romanesti<...inventii romanesti<...
Numele ţării noastre a răsunat de-a lungul timpului în toată lumea datorită inventatorilor noştrii. Acest fapt continuă şi-n zilele noastre graţie inventatorilor care reprezintă an ...
https://www.tabu.ro/tag/inventii-romanesti/
The Actin Gene Promoter of Trypanosoma-brucei | DIAL.pr - BOREALThe Actin Gene Promoter of Trypanosoma-brucei | DIAL.pr - BOREAL
The actin genes of Trypanosoma brucei are transcribed constitutively during the parasite life-cycle, by a polymerase sensitive to alpha-amanitin (1). The start region of the actin gene transcription unit was mapped by virtue of the accumulation of promoter-proximal transcripts which occurs following moderate UV irradiation (2 - 6). This region, located about 4 kilobases upstream from the genes, was able to direct transient expression of the bacterial Chloramphenicol Acetyl Transferase (CAT) gene in both bloodstream and procyclic forms of the parasite. The essential region of the promoter was defined by deletion, and appeared to be within 600 bp upstream from the putative transcription start site. It does not share significant homology with the other trypanosome promoters described so far (VSG, procyclin, rDNA), which all direct alpha-amanitin resistant transcription. ...
https://dial.uclouvain.be/pr/boreal/object/boreal:50827
Maxillaria marginata - WikispeciesMaxillaria marginata - Wikispecies
Govaerts, R. et al. 2020. Maxillaria marginata in Kew Science Plants of the World online. The Board of Trustees of the Royal Botanic Gardens, Kew. Published on the internet. Accessed: 2020 Oct 3. Reference page ...
https://species.wikimedia.org/wiki/Maxillaria_marginata
Dracaena marginata Ray of Sunshine Dragon Tree - Aquatopia ConservatoryDracaena marginata Ray of Sunshine Dragon Tree - Aquatopia Conservatory
This beautiful dragon tree will add a pop of colour wherever it is. An added bonus is just how easy it is to care for! Dracaena marginata drah-SEE-na mar-gin-ah-tah Common Names: Madagascar Dragon Tree, Fireworks Plant, Dracaena Cane Family: Dracaenaceae Origin: Africa, Madagascar Growth: Upward
https://aquatopiaplantshop.com/products/dracaena-marginata-ray-of-sunshine
Rhinoptera marginata, Lusitanian cownose ray : fisheriesRhinoptera marginata, Lusitanian cownose ray : fisheries
Found in tropical to warm temperate coastal waters, but absent from islands of western Pacific. Often forming large groups swimming near the surface and quite destructive of commercial oyster and clam beds. Feeds on bottom-living mollusks, crustaceans and fishes. Seldom marketed. Ovoviviparous, gestation period up to one year with 2-6 embryos produced. ...
https://www.fishbase.org/summary/Rhinoptera-marginata.html
Giardia lamblia RNA polymerase II: amanitin-resistant transcription.
Giardia lamblia is an early branching eukaryote, and although distinctly eukaryotic in its cell and molecular biology, transcription and translation in G. lamblia demonstrate important differences from these processes in higher eukaryotes. The cyclic octapeptide amanitin is a relatively selective inhibitor of eukaryotic RNA polymerase II (RNAP II) and is commonly used to study RNAP II transcription. Therefore, we measured the sensitivity of G. lamblia RNAP II transcription to alpha-amanitin and found that unlike most other eukaryotes, RNAP II transcription in Giardia is resistant to 1 mg/ml amanitin. In contrast, 50 microg/ml amanitin inhibits 85% of RNAP III transcription activity using leucyl-tRNA as a template. To better understand transcription in G. lamblia, we identified 10 of the 12 known eukaryotic rpb subunits, including all 10 subunits that are required for viability in Saccharomyces cerevisiae. The amanitin motif (amanitin binding site) of Rpb1 from G. lamblia has amino acid ...
http://vivo.mblwhoilibrary.org/display/publication22422
23: Euphorbia marginata (2012 season) - juria23: Euphorbia marginata (2012 season) - juria
Euphorbia marginata (2012 season) ハツユキソウ(初雪草)の花 英名：Snow-on-the-mountain トウダイグサ科 Euphorbiaceae トウダイグサ属 Euphorbia 白い総苞の中に五つの蜜線と複数の雄蕊の花と一つの雌蕊の花、 トウダイグサ科特有の花の構成ですが、この写真の花には 雌蕊が見当たらず、雄蕊だけの不稔花のよう。(結実率は悪くない) 毎年、前年に採取した種を春に蒔き、発芽率も悪くないのですが、 双葉を食害されて消えてしまうことも多く、 また、育ちもあまり良くないので、来年はある程度大きくなるまで 苗床で育ててみようかと思います。 tags: flowers 花
http://www.23hq.com/juria/photo/8009637
Agave americana ( Marginata Century Plant ) | Backyard Gardener
Very fleshy succulent forms a rosette of lance-shaped, gray-green spiky leaves with spiny, yellow margins that become white with age. Bears a tall flower s
https://www.backyardgardener.com/plantname/agave-americana-marginata-century-plant/
Frozen Sam - Darmowa Gra Online | FunnyGamesFrozen Sam - Darmowa Gra Online | FunnyGames
Graj bezpłatnie w Frozen Sam na stronie FunnyGames! Gdziekolwiek jesteś, ciesz się najlepszymi grami online bez pobierania plików! Udanej zabawy!
https://www.funnygames.pl/gra/frozen_sam.html
The Forgotten Savannas of Western Victoria: Population Dynamics of Tree-form Silver Banksia (Banksia marginata) in a Severely...The Forgotten Savannas of Western Victoria: Population Dynamics of Tree-form Silver Banksia (Banksia marginata) in a Severely...
The Forgotten Savannas of Western Victoria: Population Dynamics of Tree-form Silver Banksia (Banksia marginata) in a Severely Fragmented Landscape
https://opal.latrobe.edu.au/articles/thesis/The_Forgotten_Savannas_of_Western_Victoria_Population_Dynamics_of_Tree-form_Silver_Banksia_Banksia_marginata_in_a_Severely_Fragmented_Landscape_/12950774/2
Category:Dracaena marginata - Wikimedia CommonsCategory:Dracaena marginata - Wikimedia Commons
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. ...
https://commons.wikimedia.org/wiki/Category:Dracaena_marginata
Search Results - | PHSA LibrariesSearch Results - | PHSA Libraries
This title is licensed for one user at a time on BC Cancer-network computers. If you are denied access while on a network computer, try again later ...
https://libraries.phsa.ca/bcca/list?q=&p=1&ps=&sort=title_sort+asc&name_facet=Abraham%2C+Jame
Marginated tortoise - WikipediaMarginated tortoise - Wikipedia
The marginated tortoise was formally described by German naturalist Johann David Schoepff in 1789; its specific epithet marginata is a straightforward derivation from the Latin term for marginated. The nominate subspecies is the Greek marginated tortoise, Testudo marginata marginata. Three additional subspecies of marginated tortoises have been named: The Sardinian marginated tortoise (T. m. sarda) is the name usually used to separate the population on the island of Sardinia. These tortoises have less strongly bent tiles in the posterior of their carapaces, and the posterior of the carapace is almost smooth compared with the saw-like T. m. marginata. Clearly distinct according to morphology and entirely allopatric, it cannot be distinguished by mtDNA cytochrome b and nDNA ISSR sequence analysis.[3] Lineage sorting has not occurred to a considerable degree; consequently, the more geographically isolated Sardinian population is presumably of quite recent origin. Indeed, it appears to derive from ...
https://en.wikipedia.org/wiki/Marginated_tortoise
Eradication of Phytophthora cinnamomi from infested Eucalyptus marginata (jarrah) forest during large scale mining operations ...Eradication of Phytophthora cinnamomi from infested Eucalyptus marginata (jarrah) forest during large scale mining operations ...
2014) Eradication of Phytophthora cinnamomi from infested Eucalyptus marginata (jarrah) forest during large scale mining operations. In: 7th International Union of Research Organisations. IUFRO Working Party 7-02-09, Phytophthora in Forests and Natural Ecosystems, 9 - 14th November, Esquel, Argentina. ...
https://researchrepository.murdoch.edu.au/id/eprint/33420/
PBX 326 Chlorogalum and MassoniaPBX 326 Chlorogalum and Massonia
Greetings, Damage to the meristematic apex could do it - something that kills the chloroplasts. I dont know whether my plant is genetically variegated or not. Unlike wild plants I have seen with random white streaks in their leaves (which suggests viral infection to me), this plant always has white-edged leaves (variegata marginata). Chlorogalum is related to agave & manfreda and I dont know hoe genetics influences variegation in those plants (which are also frequently variegata marginata). I have selfed two years of seeds and none have come up variegated. But maybe it takes time to emerge and you PBXers will get lucky :-) -,,ipp , Date: Sat, 13 Oct 2012 20:00:19 -0700 , From: [email protected] , To: [email protected] , Subject: Re: [pbs] PBX 326 Chlorogalum and Massonia , , Kipp, , , What is the cause of the variegated foliage then? , , John , , --- On Sat, 10/13/12, Kipp McMichael ,[email protected], wrote: , , From: Kipp McMichael ,[email protected], , Subject: [pbs] PBX 326 ...
http://www.pacificbulbsociety.org/pbslist/2012-October/afkk444k61kqicgbgh1ncn7kn6.html
Maeotias marginataMaeotias marginata
Often measures less than 40 mm and at most 56 mm in diameter; large manubrium with 4 very long frilly lips and no gastric peduncle; 4 radial canals, each with curtain-like gonads extending onto arms of the manubrium; several prominent centripetal canals extending upward in each quadrant of the ring canal; 600 tentacles; numerous statocysts around the bell margin, each with an indistinct ocellus; milky white umbrella and pink blush around the bell margin (Ref. 2376). ...
http://sealifebase.ca/summary/Maeotias-marginata.html
Pretrazivanje organizacija
Zavod za ispitivanje materijala i konstrukcija Građevinskiog fakulteta Univerziteta „Džemal Bijedić u Mostaru sa potpunom ...
http://registar.nub.ba/pls/htmldb/f?p=111:3:10076958875626995991
Α-AmanitinΑ-Amanitin
... (alpha-Amanitin) is a cyclic peptide of eight amino acids. It is possibly the most deadly of all the amatoxins, ... Early methods to detect alpha-amanitin included thin-layer chromatography (TLC). In most solvent systems used in TLC, alpha- ... Brüggemann O, Meder M, Freitag R (September 1996). "Analysis of amatoxins alpha-amanitin and beta-amanitin in toadstool ... Alpha-amanitin is highly active in drug-resistant cells, independent of the status of expression of multi-drug resistant ...
https://en.wikipedia.org/wiki/Α-Amanitin
RNA polymeraseRNA polymerase
Alpha-amanitin Primase Werner F, Grohmann D (February 2011). "Evolution of multisubunit RNA polymerases in the three domains of ... RNA polymerase "core" from E. coli consists of five subunits: two alpha (α) subunits of 36 kDa, a beta (β) subunit of 150 kDa, ...
https://en.wikipedia.org/wiki/RNA_polymerase
AmatoxinAmatoxin
Alpha-amanitin (α-Amanitin) primarily affects the bridge helix of the RNA pol II complex, a highly conserved domain 35 amino ... This test sensitively detects alpha-amanitin and gamma-amanitin (clearly detects 10 ng/mL), and exhibits slightly less ... Alpha-amanitin binds to the bridge helix of the RNA Pol II complex and it also binds to part of the complex that is adjacent to ... One study done on mice shows that alpha-Amanitin is not absorbed through skin and therefore can not have any toxic effects. ...
https://en.wikipedia.org/wiki/Amatoxin
Mushroom poisoningMushroom poisoning
Alpha-Amanitin: For 6-12 hours, there are no symptoms. This is followed by a period of gastrointestinal upset (vomiting and ... Patients hospitalized and given aggressive support therapy almost immediately after ingestion of amanitin-containing mushrooms ... α-Amanitin, the poison produced by the death cap (Amanita phalloides) and others of the genus, is not denatured by heat. " ...
https://en.wikipedia.org/wiki/Mushroom_poisoning
HepatotoxicityHepatotoxicity
Examples include alpha-Amanitin containing mushrooms, kava, and aflatoxin producing molds. Pyrrolizidine alkaloids, which occur ...
https://en.wikipedia.org/wiki/Hepatotoxicity
Protein synthesis inhibitorProtein synthesis inhibitor
alpha-Amanitin is a powerful inhibitor of eukaryotic DNA transcription machinery. Linezolid acts at the initiation stage, ... Terao K, Uchiumi T, Endo Y, Ogata K (June 1988). "Ricin and alpha-sarcin alter the conformation of 60S ribosomal subunits at ...
https://en.wikipedia.org/wiki/Protein_synthesis_inhibitor
GalerinaGalerina
Many (though not all) Galerina contain alpha-amanitin and other amatoxins. Galerina marginata (also known as "autumn skullcap ... Klán J. (1993). "Prehled hub obsahujících amanitiny a faloidiny [A review of mushrooms containing amanitins and phalloidines ...
https://en.wikipedia.org/wiki/Galerina
Amanita citrinaAmanita citrina
It has been shown that this mushroom contains the alpha-amanitin toxin.[citation needed] However, the amounts of this toxin ...
https://en.wikipedia.org/wiki/Amanita_citrina
AmaninamideAmaninamide
It differs from alpha-amanitin in lacking the hydroxyl group on tryptophan. This alters its UV absorption spectrum but not its ...
https://en.wikipedia.org/wiki/Amaninamide
ArmillariaArmillaria
Galerina have a dark brown spore print and are deadly poisonous (alpha-amanitin) - see: mushroom poisoning. Honey fungus is a " ...
https://en.wikipedia.org/wiki/Armillaria
Lepiota brunneolilaceaLepiota brunneolilacea
It is known to contain deadly amounts of alpha-Amanitin, and was responsible for a fatal poisoning. List of deadly fungi List ...
https://en.wikipedia.org/wiki/Lepiota_brunneolilacea
RNA polymerase IIRNA polymerase II
Alpha-Amanitin inhibits RNAP II by strong interactions in the enzyme's "funnel", "cleft", and the key "bridge α-helix" regions ... RNA polymerase II is inhibited by α-Amanitin and other amatoxins. α-Amanitin is a highly poisonous substance found in many ... "The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin". Molecular Cell ... Gong, Xue Q.; Nedialkov, Yuri A.; Burton, Zachary F. (2004-06-25). "α-Amanitin Blocks Translocation by Human RNA Polymerase II ...
https://en.wikipedia.org/wiki/RNA_polymerase_II
OligopeptideOligopeptide
Alpha-amanitin is the main toxin from the species Amanita phalloides, poisonous if ingested by humans or animals. Antipain - An ... Examples of oligopeptides include: Amanitins - Cyclic peptides taken from carpophores of several different mushroom species. ...
https://en.wikipedia.org/wiki/Oligopeptide
Enzyme inhibitorEnzyme inhibitor
An example of a toxic peptide is alpha-amanitin, which is found in relatives of the death cap mushroom. This is a potent enzyme ... alpha K_{m}+\alpha ^{\prime }[S]}}={\frac {(1/\alpha ^{\prime })V_{max}[S]}{(\alpha /\alpha ^{\prime })K_{m}+[S]}}} where the ... alpha =1+{\frac {[I]}{K_{i}}}} α ′ = 1 + [ I ] K i ′ . {\displaystyle \alpha ^{\prime }=1+{\frac {[I]}{K_{i}^{\prime }}}.} Thus ... "Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization ...
https://en.wikipedia.org/wiki/Enzyme_inhibitor
Chemical test in mushroom identificationChemical test in mushroom identification
ISBN 978-0-88902-977-4. Beuhler, M; Lee, DC; Gerkin, R (2004). "The Meixner test in the detection of alpha-amanitin and false- ...
https://en.wikipedia.org/wiki/Chemical_test_in_mushroom_identification
Piet BorstPiet Borst
Kooter JM, Borst P. Alpha-amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence ...
https://en.wikipedia.org/wiki/Piet_Borst
Heinrich Otto WielandHeinrich Otto Wieland
In 1941, Wieland isolated the toxin alpha-amanitin, the principal active agent of one of the world's most poisonous mushrooms ...
https://en.wikipedia.org/wiki/Heinrich_Otto_Wieland
Amanita vernaAmanita verna
Just like the death cap, this organism contains a fatal dose of alpha-amanitin, which causes liver failure if not treated ... Fungi portal Amanitin List of Amanita species List of deadly fungi Mushroom poisoning "GSD Species Synonymy: Amanita verna ( ...
https://en.wikipedia.org/wiki/Amanita_verna
Drosophila quinaria species groupDrosophila quinaria species group
... such as ibotenic acid and alpha-amanitin. Mushroom sites also host a number of natural enemies. For instance, as a consequence ... Bowman DD (November 2011). "Introduction to the alpha-proteobacteria: Wolbachia and Bartonella, Rickettsia, Brucella, Ehrlichia ...
https://en.wikipedia.org/wiki/Drosophila_quinaria_species_group
AucubinAucubin
... was found to protect against liver damage induced by carbon tetrachloride or alpha-amanitin in mice and rats when 80 mg ...
https://en.wikipedia.org/wiki/Aucubin
ProcyclinProcyclin
... genes located in an unusually small alpha-amanitin-resistant transcription unit: PARP promoter activity assayed by transient ...
https://en.wikipedia.org/wiki/Procyclin
Peptide bondPeptide bond
Some peptides, like alpha-amanitin, are called ribosomal peptides as they are made by ribosomes, but many are nonribosomal ... In organic chemistry, a peptide bond is an amide type of covalent chemical bond linking two consecutive alpha-amino acids from ... C1 (carbon number one) of one alpha-amino acid and N2 (nitrogen number two) of another, along a peptide or protein chain. It ...
https://en.wikipedia.org/wiki/Peptide_bond
Pholiotina rugosaPholiotina rugosa
They produce alpha-amanitin, a cyclic peptide that is highly toxic to the liver and is responsible for many deaths by poisoning ...
https://en.wikipedia.org/wiki/Pholiotina_rugosa
Amanita exitialisAmanita exitialis
Amatoxins content (alpha-amanitin and beta-amanitins especially alpha-amanitin) in the cap, stem or volva of A. exitialis was ... The content and distribution of the main amatoxins (alpha-amanitin, beta-amanitin) and phallotoxins (phallacidin, phallisin, ... Zhang P, Chen Z, Hu J, Wei B, Zhang Z, Hu W (2005). "Production and characterization of Amanitin toxins from a pure culture of ...
https://en.wikipedia.org/wiki/Amanita_exitialis
Lepiota brunneoincarnataLepiota brunneoincarnata
It is known to contain deadly amounts of alpha-amanitin and was responsible for a fatal poisoning in Spain in 2002, and a ... A family in Salon-de-Provence in France was poisoned after mistaking them for the grey knight (Tricholoma terreum). Amanitin ... Intravenous silibinin has a role in reducing amanitin uptake. Other specific measures include penicillin G and n-acetylcysteine ...
https://en.wikipedia.org/wiki/Lepiota_brunneoincarnata
List of biomoleculesList of biomolecules
Aequorin Aflatoxin Agar Alamethicin Alanine Albumins Aldosterone Aleurone Alpha-amanitin Alpha-MSH (Melaninocyte stimulating ... see Alpha-amanitin Amino acid Amylase (also see α-amylase) Anabolic steroid Anandamide (ANA) Androgen Anethole Angiotensinogen ...
https://en.wikipedia.org/wiki/List_of_biomolecules
Galerina sulcicepsGalerina sulciceps
More toxic than the deathcap (Amanita phalloides), G. sulciceps has been shown to contain the toxins alpha- (α-), beta- (β-) ... Although these clinical symptoms are inconsistent with those of amatoxin poisoning, the presence of α-, β- and γ- amanitins in ... and gamma- (γ-) amanitin; a series of poisonings in Indonesia in the 1930s resulted in 14 deaths from the consumption of this ... The survey of fungi containing amanitins and phalloidins]. Časopis Lékařů Českých (in Czech). 132: 449-51. Besl H. (1981). " ...
https://en.wikipedia.org/wiki/Galerina_sulciceps
List of MeSH codes (D12.644)List of MeSH codes (D12.644)
... gtp-binding protein alpha subunits, g12-g13 MeSH D12.644.360.375.100.200 - gtp-binding protein alpha subunits, gi-go MeSH ... amanitins MeSH D12.644.456.073 - angiotensins MeSH D12.644.456.073.021 - angiotensin i MeSH D12.644.456.073.041 - angiotensin ... gtp-binding protein alpha subunits, gq-g11 MeSH D12.644.360.375.100.400 - gtp-binding protein alpha subunits, gs MeSH D12.644. ... MeSH D12.644.050.200 - defensins MeSH D12.644.050.200.050 - alpha defensins MeSH D12.644.050.200.075 - beta defensins MeSH ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.644)
Cyclic peptideCyclic peptide
... between the alpha carboxyl of one residue to the alpha amine of another). The smallest such species are 2,5-diketopiperazines, ... Examples include: Amanitins Bacitracin Colistin Ciclosporin Dactinomycin Daptomycin Gramicidin S Hymenistatin Microcystins ... Cyclic isopeptides contain at least one non-alpha amide linkage, such as a linkage between the side chain of one residue to the ... for example in amanitin. Many cyclic peptides have been discovered in nature and many others have been synthesized in the ...
https://en.wikipedia.org/wiki/Cyclic_peptide
List of MeSH codes (D04)List of MeSH codes (D04)
MeSH D04.345.051.500 - crown ethers MeSH D04.345.103.222 - alpha-cyclodextrins MeSH D04.345.103.333 - beta-cyclodextrins MeSH ... amanitins MeSH D04.345.566.075 - bacitracin MeSH D04.345.566.142 - capreomycin sulfate MeSH D04.345.566.235 - cyclosporins MeSH ... 20-alpha-dihydroprogesterone MeSH D04.808.745.745.654.829.395 - hydroxyprogesterones MeSH D04.808.745.745.654.829.395.400 - 17- ... 5-alpha-dihydroprogesterone MeSH D04.808.745.558.050 - alfaxalone alfadolone mixture MeSH D04.808.745.558.783 - ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D04)
List of MeSH codes (D23)List of MeSH codes (D23)
15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid MeSH D23.469.050.175.725.740 - prostaglandins a MeSH D23.469 ... amanitins MeSH D23.946.587.272 - citrinin MeSH D23.946.587.370 - cytochalasins MeSH D23.946.587.370.370 - cytochalasin b MeSH ... 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid MeSH D23.469.700.645 - prostaglandins a, synthetic MeSH ... transforming growth factor alpha MeSH D23.348.479.992.720 - transforming growth factor beta MeSH D23.348.479.996 - wnt proteins ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D23)
Molecular basis of translocation, alpha-amanitin inhibition, and CPD damage recognition by RNA polymerase IIMolecular basis of translocation, alpha-amanitin inhibition, and CPD damage recognition by RNA polymerase II
alpha-amanitin, amanitin, nuclear protein, RNA polymerase II, elongation complex, mRNA, enzyme inhibition, dna damage, dna ... alpha-amanitin, amanitin, nuclear protein, RNA polymerase II, elongation complex, mRNA, enzyme inhibition, dna damage, dna ... Crystal soaking with the inhibitor alpha-amanitin locked the EC in a new state that we identified as a translocation ... Crystal soaking with the inhibitor alpha-amanitin locked the EC in a new state that we identified as a translocation ...
https://edoc.ub.uni-muenchen.de/8646/
IMSEAR at SEARO: Nucleolar RNA synthesis & segregation pattern in alpha-amanitin treated rat kangaroo cells.
Ghosh S. Nucleolar RNA synthesis & segregation pattern in alpha-amanitin treated rat kangaroo cells. Indian Journal of ... Nucleolar RNA synthesis & segregation pattern in alpha-amanitin treated rat kangaroo cells. ...
https://imsear.searo.who.int/handle/123456789/62289?locale=es
Erowid.org: References DatabaseErowid.org: References Database
The Meixner test in the detection of alpha-amanitin and false-positive... Ann Emerg Med. 2004. ...
https://erowid.org/references/refs.php?S=Lee_D&SField=Author
The AMEDEO Literature GuideThe AMEDEO Literature Guide
Anti-CD37 alpha-amanitin-conjugated antibodies as potential therapeutic weapons for Richter syndrome.. Blood. 2022;140:1565- ... Genomic Landscape of TCR Alpha-Beta and TCR Gamma-Delta T-Large Granular Lymphocyte Leukemia.. Blood. 2022 Jan 11. pii: 483429 ...
https://amedeo.com/medicine/leu/blood.htm
SMART: S1 domain annotationSMART: S1 domain annotation
Alpha-amanitin inhibited complete RNA polymerase II elongation complex. 2waq. The complete structure of the archaeal 13-subunit ... crystal structure of the eIF2 alpha subunit from saccharomyces cerevisia. 1q8k. Solution structure of alpha subunit of human ... Crystal structure of intact alpha subunit of aIF2 from Pyrococcus abyssi. 1zo1. IF2, IF1, and tRNA fitted to cryo-EM data OF E ... Structure of the archaeal initiation factor eIF2 alpha-gamma heterodimer from Sulfolobus solfataricus complexed with GDPNP. ...
https://smart.embl.de/smart/do_annotation.pl?DOMAIN=S1&START=234&END=307&E_VALUE=3.52e-18&TYPE=SMART&BLAST=AIGDIYNGKVTSIMQFGCFVQLEGLRKRWEGLVHISELRREGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMK
Deadly mushroom chemistry | Feature | Chemistry WorldDeadly mushroom chemistry | Feature | Chemistry World
Updated 19 March with clarified alpha-amanitin structure image; updated 4 April with clarified image captions ... In particular, a-amanitin has a high specificity for RNA polymerase II in the liver. By inhibiting this enzyme it prevents the ... The Meixner test uses concentrated hydrochloric acid and newspaper to determine the presence of the deadly toxin a-amanitin.7 ...
https://www.chemistryworld.com/features/deadly-mushroom-chemistry/5970.article
CybaseCybase
Amanita bisporigera alpha-amanitin (AMA1) mRNA, complete cds. Structure. Alpha-amanitin inhibited complete RNA polymerase II ... Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin. ... alpha-amanitin(518) Protein Card. General Information. Name. alpha-amanitin Alternative name(s). gamma-amanitin ...
https://cybase.org.au/?page=card&table=protein&id=518
NEW (2008) DeCS DESCRIPTORS WITH SCOPE NOTES (UNIT RECORD FORMAT; 21/02/2008NEW (2008) DeCS DESCRIPTORS WITH SCOPE NOTES (UNIT RECORD FORMAT; 21/02/2008
HN - 2008 MH - Alpha-Amanitin UI - D053959 MN - D04.345.566.050.111 MN - D12.644.456.050.111 MN - D12.644.641.050.111 MN - ... beta-Hexosaminidase alpha Chain UI - D054820 MN - D08.811.277.450.483.180.750.500 MS - The alpha subunit of hexosaminidase A. ... HN - 2008; use AMANITINS 1980-2007 FX - Mushroom Poisoning MH - Withanolides UI - D054358 MN - D04.808.247.222.537.888 MN - ... It is comprised of two catalytic subunits, referred to as alpha and beta, that form a dimer. In addition two regulatory ...
https://decs.bvs.br/I/dcsnew2008.txt
Silymarin | ≥99%(HPLC) | Selleck | Antioxidant chemicalSilymarin | ≥99%(HPLC) | Selleck | Antioxidant chemical
... protecting the cell membrane from radical-induced damage and blockage of the uptake of toxins such as alpha-amanitin. [2] ...
https://www.selleckchem.com/products/Silymarin%28Silybin-B%29.html
Search Strains - Caenorhabditis Genetics Center (CGC) - College of Biological Sciences
Sensitive to alpha-amanitin. Heterozygotes are semi-Dpy and segregate semi-Dpy, Vul, dead embryos, and Dpy. Dpy progeny arrest ... Sensitive to alpha-amanitin. [NOTE: formerly described as ama-1(m118m370m414), it has been determined that m414 was reversion ... Sensitive to alpha-amanitin. Reference: Bowman EA, Riddle DR, Kelly WG. G3 November 2011 1:411-416. ...
https://cgc.umn.edu/strain/search?st1=m37&sf1=all
DeCSDeCS
Alpha Amanitin. Alpha Amanitine. Alpha-Amanitine. Tree number(s):. D04.345.566.050.111. D12.644.456.050.111. D12.644.641.050. ... Alpha-Amanitin - Preferred Concept UI. M0000844. Scope note. A cyclic octapeptide with a thioether bridge between the cystine ...
https://decs.bvsalud.org/en/ths/resource/?id=52652&filter=ths_exact_term&q=ALFA+AMANITINA
Value Set Details
Alpha+gamma-amanitin Ur EIA-mCnc. Alpha-Amanitin + gamma-Amanitin [Mass/volume] in Urine by Immunoassay. LOINC. Lab Test Name ( ...
http://phinvads.cdc.gov/vads/ViewValueSet.action?oid=2.16.840.1.114222.4.11.4243
Value Set Concept Details
Alpha+gamma-amanitin Ur IA-mCnc Code System Concept Status. Published. Code System Preferred Concept Name. Alpha-Amanitin + ...
https://phinvads.cdc.gov/vads/ViewValueSetConcept.action?id=7223433E-AFC1-E311-8F3C-0017A477041A
GARIBOLDI, SILVIAGARIBOLDI, SILVIA
... and alpha-amanitin in mice 1-set-2009 L. ZanobbioM. PalazzoS. GariboldiG.F. DusioD. CardaniV. MauroF. MarcucciA. BalsariC. ... Intestinal glucose uptake protects liver from lipopolysaccharide and d-galactosamine, acetaminophen, and alpha-amanitin in mice ...
https://air.unimi.it/cris/rp/rp12078
Mycology | Concise Medical KnowledgeMycology | Concise Medical Knowledge
Alpha-amanitin is the main toxin from the species amanita phalloides, poisonous if ingested by humans or animals. Toxicology of ... Amanitin Amanitin Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA ...
https://www.lecturio.com/concepts/mycology-overview/
Catriona Shared Created - 41 PicmonicsCatriona Shared 'Created' - 41 Picmonics
Alpha Amanitin inhibits RNA pol 2. Nucleolus Transcribes RRNA. Rifampin inhibits RNA pol in prokaryotes. Actinomycin D Inhibits ... TGF-Alpha. Protein Loss. Hypoalbuminemia. Peripheral Edema. Also called hypoproteinemic hypertrophic gastropathy. ...
https://www.picmonic.com/playlists/b625538783209776a1084da153f5ce86
Düzce Üniversitesi Tıp Dergi | DÜZCE TIP FAKÜLTESİ DERGİSİ 2015; 17(1)
... alpha-amanitin. The knowledge of the poisonous mushroom species including alpha- amanitin is important for the treatment and ... Deadly Poisonous Turkish Mushrooms Containing Alpha Amanitin. Ilgaz Akata, Ertuğrul Kaya, İsmail Yılmaz, Sinan Bakırcı, Recep ... According to literature, nine poisonous mushroom species which include alpha-amanitin have so far been reported from Turkey. ... In this review, the mushrooms containig alpha-amanitin and causing deadly mushroom poisinings were listed and given information ...
http://tipdergi.duzce.edu.tr/4859-sayfa-duzce-tip-fakultesi-dergisi-2015
Toxic fruits and vegetables? Inspired by US chemicals scare fundraising gimmick, tainted disinformation comes to Europe -...Toxic fruits and vegetables? Inspired by US chemicals scare fundraising gimmick, tainted disinformation comes to Europe -...
Heck, theyre natural, how bad can they be? (see all natural alpha-amanitin, DIMBOA, cyanide) ...
https://tomoemaru.com/toxic-fruits-and-vegetables-inspired-by-us-chemicals-scare-fundraising-gimmick-tainted-disinformation-comes-to-europe/
CybaseCybase
Amanita bisporigera alpha-amanitin (AMA1) mRNA, complete cds. Amanita phalloides. Mushroom. cliotide T12. alpha-amanitin. alpha ... amanitin precursor. 96. Amanita bisporigera phallacidin (PHA1) mRNA, complete cds. Amanita phalloides. Mushroom. phallacidin ...
https://cybase.org.au/index.php?page=list&table=nucleicacid&sort_by=ID&sort_by=ID
Untersuchungen zur Struktur und Funktion der Balbianiringe von Chironomus tentansUntersuchungen zur Struktur und Funktion der Balbianiringe von Chironomus tentans
In Gegenwart von alpha-Amanitin bleibt die Bandenmarkierung aus. Die Polymerasenaktivität ist mit Toluidinblau in nativen IS- ...
https://bibliographie.uni-tuebingen.de/xmlui/handle/10900/49184
NR 4.0 01515.1NR 4.0 01515.1
Alpha-amanitin inhibited complete RNA polymerase II elongation complex. X-RAY DIFFRACTION. 3.4. 2008-06-17. ... Alpha-amanitin inhibited complete RNA polymerase II elongation complex. X-RAY DIFFRACTION. 3.4. 10. ...
http://rna.bgsu.edu/rna3dhub/nrlist/view/NR_4.0_01515.1
Zarmik Moqtaderi, Ph.D., D.E.A. | Harvard Catalyst Profiles | Harvard CatalystZarmik Moqtaderi, Ph.D., D.E.A. | Harvard Catalyst Profiles | Harvard Catalyst
Alpha-Amanitin. *Amino Acid Sequence. *Animals. *Bacterial Proteins. *Base Sequence. *Binding Sites ...
https://connects.catalyst.harvard.edu/Profiles/display/Person/73526/Network/ResearchAreas
Pesquisa | Biblioteca Virtual em Saúde - BRASILPesquisa | Biblioteca Virtual em Saúde - BRASIL
Characterization of the RAS/RAF/ERK Signal Cascade as a Novel Regulating Factor in Alpha-Amanitin-Induced Cytotoxicity in Huh-7 ... The well-known hepatotoxicity mechanism resulting from alpha-amanitin (α-AMA) exposure arises from RNA polymerase II (RNAP II) ... We thus performed in vitro primary GC cultures with palmitate, palmitoleate, stearate, oleate, linoleate, and alpha-linolenate ...
https://pesquisa.bvsalud.org/brasil/?lang=pt&q=mh:Sistema+de+Sinaliza%C3%A7%C3%A3o+das+MAP+Quinases/fisiologia
CDC Science ClipsCDC Science Clips
N10-alpha-amanitin and a modified amanitin methionine sulfoxide synthetic peptide. Using the (15)N10-alpha-amanitin internal ... Detection of alpha-, beta-, and gamma-amanitin in urine by LC-MS/MS using (15)N10-alpha-amanitin as the internal standard ... The LFIA detects as little as 10 ng/mL of alpha-amanitin (alpha-AMA) or gamma-AMA, and 100 ng/mL of beta-AMA in urine matrices ... The presented urinary diagnostic test is the first method to use an isotopically labeled alpha-amanitin with the ability to ...
https://phgkb.cdc.gov/PHGKB/cdcSCFinder.action?Mysubmit=init&action=search&query=Hamelin+EI+
Publications | Page 6 | Microbiology and ImmunologyPublications | Page 6 | Microbiology and Immunology
Interaction of several class II and III RNA polymerases with two families of 7-substituted alpha-amanitin.. Biochemistry. 21( ... Regiospecific arylazo substitution into alpha-amanitin with retention of inhibitory properties against eukaryotic class II RNA ...
https://microbiology.weill.cornell.edu/publications?page=5&s=author&o=asc&f%5Bauthor%5D=2706
DNA-Directed RNA Polymerases | Profiles RNS
In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of ...
https://profiles.jefferson.edu/display/17569
NEW (2008) DeCS DESCRIPTORS WITH SCOPE NOTES (UNIT RECORD FORMAT; 21/02/2008
HN - 2008 MH - Alpha-Amanitin UI - D053959 MN - D04.345.566.050.111 MN - D12.644.456.050.111 MN - D12.644.641.050.111 MN - ... beta-Hexosaminidase alpha Chain UI - D054820 MN - D08.811.277.450.483.180.750.500 MS - The alpha subunit of hexosaminidase A. ... HN - 2008; use AMANITINS 1980-2007 FX - Mushroom Poisoning MH - Withanolides UI - D054358 MN - D04.808.247.222.537.888 MN - ... It is comprised of two catalytic subunits, referred to as alpha and beta, that form a dimer. In addition two regulatory ...
https://decs2014.bvsalud.org/I/dcsnew2008.txt
PolymeraseInhibitionToxinsTranslocationLiverTherapeuticSubunitBasisClassCellsDeathStudiesCyclic octapeptideToxicityToxinPhalloidesMushroomGammaInhibitorMonoclonal antibodySensitiveEnzymeBetaEffectsProteinsClinicalStudyGeneProcess
Polymerase4
  • In particular, a-amanitin has a high specificity for RNA polymerase II in the liver. (chemistryworld.com)
  • [1] The mechanisms of action of silymarin involve different biochemical events, such as the stimulation of the synthetic rate of ribosomal RNA (rRNA) species through stimulation of polymerase I and rRNA transcription, protecting the cell membrane from radical-induced damage and blockage of the uptake of toxins such as alpha-amanitin. (selleckchem.com)
  • 1983. Regiospecific arylazo substitution into alpha-amanitin with retention of inhibitory properties against eukaryotic class II RNA polymerase. . (cornell.edu)
  • By blocking translocation of RNA Polymerase II using these inhibitors we have shown that there is a significant increase in the amount of unmodified H4 and H3 and in the case of inhibition by alpha amanitin also the loss of p300 from the RNAPII complex. (und.edu)
Inhibition1
  • This thesis describes studies on the molecular mechanisms of Pol II translocation, alpha-amanitin inhibition and DNA lesion recognition by Pol II. (uni-muenchen.de)
Toxins2
  • Its primary toxins are a-amanitin and b-amantin which destroy the liver and kidneys. (appcomrade.com)
  • It packs a punch with a-amanitin toxins and phallotoxins. (appcomrade.com)
Translocation3
  • Crystal soaking with the inhibitor alpha-amanitin locked the EC in a new state that we identified as a translocation intermediate at 3.4 Å resolution. (uni-muenchen.de)
  • Our results support a Brownian ratchet mechanism of elongation that involves swinging of the trigger loop between open, wedged, and closed positions, and suggest that alpha-amanitin impairs nucleotide incorporation and translocation by trapping the trigger loop and bridge helix in a translocation intermediate. (uni-muenchen.de)
  • These results suggest that the extent of hyperacetylation of H4 and H3 during transcription alternates between hyperacetylation directed by an RNAPII associated HAT and deacetylation directed by an HDAC at other sites ( Ref ).We also studied dynamic histone hyperacetylation by using inhibitors of transcription such as alpha amanitin and DRB to block the translocation of RNAPII in the coding region. (und.edu)
Liver1
  • Ingesting Silybum marianum (Blessed milk thistle) has been shown to lessen the effects of the toxin alpha-amanitin on the liver and help regrow damaged cells. (appcomrade.com)
Therapeutic1
  • Anti-CD37 alpha-amanitin-conjugated antibodies as potential therapeutic weapons for Richter syndrome. (amedeo.com)
Subunit3
  • Several putative nicotinic acetylcholine receptor (nAChR) subunit clones were isolated by screening a lambda library of Caenorhabditis elegans genomic DNA with a probe derived from the Drosophila melanogaster ard gene (a non-alpha nicotinic acetylcholine receptor subunit clone). (wormbase.org)
  • Recently, similar findings have been obtained for the product of acr-3 , another non-alpha nAChR subunit encoding gene located 281bp downstream from acr-2 on the X chromosome and in the same orientation. (wormbase.org)
  • The cDNA encodes a putative non-a subunit of a nicotinic acetylcholine receptor which shows many of the conserved features of vertebrate and invertebrate non-alpha nAChR subunits, for instance the four putative transmembrane domains and the cysteine delimited extracellular loop. (wormbase.org)
Basis1
  • In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (jefferson.edu)
Class1
  • 1982. Interaction of several class II and III RNA polymerases with two families of 7'-substituted alpha-amanitin. . (cornell.edu)
Cells2
  • IMSEAR at SEARO: Nucleolar RNA synthesis & segregation pattern in alpha-amanitin treated rat kangaroo cells. (who.int)
  • Blessed milk thistle is believed to help protect cells from the destruction of a-amanitin. (appcomrade.com)
Death1
  • The European destroying angel is similar to the death cap because its main toxin is also a-amanitin. (appcomrade.com)
Studies2
  • Studies on the regulation of expression of these linked non-alpha subunits are underway. (wormbase.org)
  • The functional expression studies of nematode nicotinic acetylcholine receptors reported here support the interpretation that the differentiation between alpha and non-alpha subunits dates back to the earliest stages of metazoan evolution. (wormbase.org)
Cyclic octapeptide2
  • [ 1 ] A. phalloides contains the alpha variety of amanitin, a cyclic octapeptide thought to be the primary agent of toxicity in humans. (medscape.com)
  • HN - 2008 (1997) MH - Alpha-Amanitin UI - D053959 MN - D4.345.566.50.111 MN - D12.644.456.50.111 MN - D12.644.641.50.111 MN - D23.946.587.175.111 MS - A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. (nih.gov)
Toxicity1
  • What is the restoring role of chrysin in alpha amanitin toxicity? (ibu.edu.tr)
Toxin2
  • With a surprising amount of diversity, fruit fly species have adapted many niche preferences, such as a tolerance for alpha-amanitin, or alpha-amanitin, a toxin found in the Amanita genus of poisonous mushrooms. (brightsurf.com)
  • Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals. (bvsalud.org)
Phalloides2
  • Amaç: Düzce ili sınırlarında 2010 yılında toplanan Amanita phalloides mantarındaki alfa amanitin toksin düzeyinin HPLC yöntemiyle ölçümü amaçlanmıştır. (ibu.edu.tr)
  • Background/aim: Alpha- and beta-amanitins are the main toxins of the poisonous Amanita phalloides mushroom. (ibu.edu.tr)
Mushroom3
  • But while the phallotoxins are present in a higher concentration, in every part of the mushroom (2), it is the amatoxins that get the blame, particularly α-amanitin. (naturespoisons.com)
  • use AMANITINS 1980-2007 FX - Mushroom Poisoning MH - Amplified Fragment Length Polymorphism Analysis UI - D054458 MN - E5.393.290.382 MN - E5.393.620.500.324 MS - The detection of RESTRICTION FRAGMENT LENGTH POLYMORPHISMS by selective PCR amplification of restriction fragments derived from genomic DNA followed by electrophoretic analysis of the amplified restriction fragments. (nih.gov)
  • It is very sensitive to mushroom poison a -amanitin. (50webs.org)
Gamma2
  • We aimed to obtain gamma amanitin with high purity through a purification process and compare toxic effects of alpha, beta, and gamma amanitin. (ibu.edu.tr)
  • 7. Growth inhibition of pancreatic cancer cells through activation of peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha pathway. (nih.gov)
Inhibitor2
  • Additional inhibitors of phalloidin uptake mediated by SLC21A6 included the immunosuppressive drugs cyclosporin A, FK506, and rapamycin, whereas alpha-amanitin was only a weak inhibitor. (nih.gov)
  • The active ingredient Finasteride is a type II 5-alpha reductase inhibitor and has a trichogenic activity (hair growth-promoting). (mymeds10.us)
Monoclonal antibody1
  • 9. Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma. (nih.gov)
Sensitive2
  • Sensitive to alpha-amanitin. (umn.edu)
  • There is an activity that is sensitive both to rifamycin and to alpha-amanitin. (omicsdi.org)
Enzyme1
  • It hinders the action of 5-alpha reductase enzyme, responsible for the conversion of testosterone to dihydrotestosterone (DHT). (mymeds10.us)
Beta2
  • the most significant of these are the alpha and beta subtypes of amanitin. (medscape.com)
  • Amaç: Beta amanitin nadiren bilimsel araştırmalarda kullanılmakta ve kullanımı gün geçtikçe artmaktadır. (ibu.edu.tr)
Effects1
  • Inhibition of hepatic deoxyribonucleic acid-dependent ribonucleic acid polymerases by the exotoxin of Bacillus thuringiensis in comparison with the effects of -amanitin and cordycepin. (omicsdi.org)
Proteins1
  • Furthermore, latest studies have alpha-Boswellic acid showed that many chromatin binding proteins also bind different types of RNA such mRNA products to regulate the turnover of these mRNAs (examined in11). (nationalbonehealthalliance.org)
Clinical1
  • The first human clinical studies using alpha-lipoic acid (ALA) in the United States were conducted by Fredrick C. Bartter, Burton M. Berkson, and associates from the National Institutes of Health in the 1970's. (zubiaga.org)
Study1
  • Thomas Werner, an assistant professor of biological sciences at Michigan Tech, is the corresponding author of the new PLOS ONE paper, and the study builds on his previous work showing how alpha-amanitin resistance may be related to pesticide resistance in Asian fruit fly strains. (brightsurf.com)
Gene1
  • These research supply the initial immediate comparative function of PARylation and PARP1 in RNA balance and decay, adding a fresh alpha-Boswellic acid dimension concerning how PARP1 regulates gene appearance. (nationalbonehealthalliance.org)
Process1
  • It acts as an antagonist to TNF alpha, thus effectively blocks the inflammatory process in numerous chronic inflammatory diseases like Crohn's disease, ulcerative colitis and inflammatory arthritis. (buhlmannlabs.ch)
Amatoxin Toxicity: Practice Essentials, Pathophysiology, Etiology
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Amanita phalloides Mushroom Poisonings - Northern California, December 2016 | MMWR
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Deadly mushroom chemistry | Feature | Chemistry World
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Zarmik Moqtaderi, Ph.D., D.E.A. | Harvard Catalyst Profiles | Harvard Catalyst
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(doctorschar.com)
Uvex silv-Air c 3200 FFP2 Faltmaske | ures // Atemschutzberater
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Arabidopsis Seed Proteome - The joint laboratory CNRS / Bayer CropScience
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MyBioSource - hla-a.com
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MeSH Browser
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Amanita Mushroom Poisoning - Drugs and Lactation Database (LactMed®) - NCBI Bookshelf
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Dynamic reorganization of the AC16 cardiomyocyte transcriptome in response to TNFα signaling revealed by integrated genomic...
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