DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentInformation Science
alpha 1-Antichymotrypsinalpha 1-AntitrypsinChymotrypsinSerine Proteinase InhibitorsCathepsin GSerpinsFluoroimmunoassayPancreatinImmunoelectrophoresis, Two-DimensionalCathepsinsAcute-Phase ProteinsPancreatic ElastaseProstate-Specific Antigenalpha 1-Antitrypsin DeficiencyOrosomucoidSerine EndopeptidasesProtease InhibitorsTrypsin InhibitorsLeukocyte ElastaseProtein C InhibitorElectrophoresis, Polyacrylamide GelMolecular Sequence Dataalpha-Macroglobulins
alpha 1-Antichymotrypsin
Glycoprotein found in alpha(1)-globulin region in human serum. It inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. It is a member of the serpin superfamily.
alpha 1-Antitrypsin
Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.
Chymotrypsin
A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
Serine Proteinase Inhibitors
Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES.
Cathepsin G
A serine protease found in the azurophil granules of NEUTROPHILS. It has an enzyme specificity similar to that of chymotrypsin C.
Serpins
A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes. This family includes alpha 1-antitrypsin, angiotensinogen, ovalbumin, antiplasmin, alpha 1-antichymotrypsin, thyroxine-binding protein, complement 1 inactivators, antithrombin III, heparin cofactor II, plasminogen inactivators, gene Y protein, placental plasminogen activator inhibitor, and barley Z protein. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES, and some serpins occur in plants where their function is not known.
Fluoroimmunoassay
The use of fluorescence spectrometry to obtain quantitative results for the FLUORESCENT ANTIBODY TECHNIQUE. One advantage over the other methods (e.g., radioimmunoassay) is its extreme sensitivity, with a detection limit on the order of tenths of microgram/liter.
Pancreatin
A mammalian pancreatic extract composed of enzymes with protease, amylase and lipase activities. It is used as a digestant in pancreatic malfunction.
Immunoelectrophoresis, Two-Dimensional
Immunoelectrophoresis in which a second electrophoretic transport is performed on the initially separated antigen fragments into an antibody-containing medium in a direction perpendicular to the first electrophoresis.
Cathepsins
A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES.
Acute-Phase Proteins
Proteins that are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. These proteins can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumor markers.
Pancreatic Elastase
A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.
Prostate-Specific Antigen
A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
alpha 1-Antitrypsin Deficiency
Deficiency of the protease inhibitor ALPHA 1-ANTITRYPSIN that manifests primarily as PULMONARY EMPHYSEMA and LIVER CIRRHOSIS.
Orosomucoid
Serine Endopeptidases
Any member of the group of ENDOPEPTIDASES containing at the active site a serine residue involved in catalysis.
Protease Inhibitors
Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).
Trypsin Inhibitors
Serine proteinase inhibitors which inhibit trypsin. They may be endogenous or exogenous compounds.
Leukocyte Elastase
An enzyme that catalyzes the hydrolysis of proteins, including elastin. It cleaves preferentially bonds at the carboxyl side of Ala and Val, with greater specificity for Ala. EC 3.4.21.37.
Protein C Inhibitor
A member of the serpin family of proteins that is found in plasma and urine. It is dependent on heparin and is able to inhibit activated PROTEIN C; THROMBIN; KALLIKREIN; and other SERINE ENDOPEPTIDASES.
Electrophoresis, Polyacrylamide Gel
Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
alpha-Macroglobulins
Glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters.

Genes, oxidative stress, and the risk of chronic obstructive pulmonary disease. (1/204)

BACKGROUND: The first-pass metabolism of foreign compounds in the lung is an important protective mechanism against oxidative stress. We investigated whether polymorphisms in the gene for microsomal epoxide hydrolase (mEPHX), an enzyme involved in this protective process, had any bearing on individual susceptibility to the development of chronic obstructive pulmonary disease (COPD) and emphysema. METHODS: We designed PCR-based genotyping assays to detect variant forms of mEPHX that confer slow and fast activity. We used these assays to screen 203 blood-donor controls and groups of patients with asthma (n = 57), lung cancer (n = 50), COPD (n = 68), and emphysema (n = 94), who were attending specialised clinics in Edinburgh, UK. FINDINGS: The proportion of individuals with innate slow mEPHX activity (homozygotes) was significantly higher in both the COPD group and the emphysema group than in the control group (COPD 13 [19%] vs control 13 [6%]; emphysema 21 [22%] vs 13 [6%]). The odds ratios for homozygous slow activity versus all other phenotypes were 4.1 (95% CI 1.8-9.7) for COPD and 5.0 (2.3-10.9) for emphysema. INTERPRETATION: Genetic polymorphisms in xenobiotic enzymes may have a role in individual susceptibility to oxidant-related lung disease. Epoxide derivatives of cigarette-smoke components may be the cause of some of the lung damage characteristics of these diseases.  (+info)

Giardia intestinalis is unlikely to be a major cause of the poor growth of rural Gambian infants. (2/204)

Parasite-specific plasma immunoglobulins have been used to indicate the presence of Giardia intestinalis infection in 60 infants living in a rural area of The Gambia. Infants were studied longitudinally between 2 and 8 mo of age. The median age for first exposure to G. intestinalis was between 3 and 4 mo, and by 8 mo all but 3 infants (95%) showed a positive titer on at least one occasion. Raised Giardia-specific IgM titers were associated with reduced weight gain in the 2 wk preceding a positive titer, but catch-up growth occurred in the following 2 wk. IgM antibody titers were also positively associated with intestinal permeability (lactulose/mannitol ratio), urinary lactose excretion, plasma concentrations of alpha1-antichymotrypsin and total IgM, IgA and IgG immunoglobulins. However, infant growth over the whole 6-mo period (i.e., between 2 and 8 mo of age) was not related to mean Giardia-specific antibody titers, nor the time of first exposure to the parasite. The data suggest that giardiasis in these very young breast-fed children occurs as a mild, acute disease, and its presence could not explain the marked, long-term growth faltering observed in many of the subjects.  (+info)

Anti-free prostate-specific antigen monoclonal antibody epitopes defined by mimotopes and molecular modeling. (3/204)

BACKGROUND: Prostate-specific antigen (PSA) is an important marker for the diagnosis and management of prostate cancer, and the free PSA/total PSA ratio has been shown to be efficient for distinguishing prostate cancer from benign prostatic hyperplasia. We report here the characterization of seven mouse monoclonal antibodies (mAbs) and the partial localization of two conformational epitopes identified by anti-free PSA mAbs. METHODS: The mAbs were studied by competition and sandwich assays, and the epitope localization of the two anti-free PSA mAbs (6C8D8 and 5D3D11) was performed using phage displayed peptide libraries and molecular modeling. RESULTS: The seven mAbs were classified into three groups according to their recognition specificities and their ability to inhibit the enzymatic activity of PSA and the formation of PSA-alpha1-antichymotrypsin (ACT) complex. Among the anti-free PSA mAb group, 6C8D8 recognized the phage displayed peptide RKLRPHWLHFHPVAV, two parts of which presented similarities with two regions distant on the PSA sequence but joined in the tridimensional structure. mAb 5D3D11 recognized the peptide DTPYPWGWLLDEGYD, which is similar to a PSA region located on the board of the groove containing the PSA enzymatic site. Both epitopes were located in the theoretical ACT binding site described previously. Moreover, these mAbs were able to inhibit the enzymatic activity of PSA. CONCLUSIONS: These epitope localizations are in agreement with the ability of both mAbs to inhibit enzymatic activity and ACT fixation. The results presented here could bring information for the generation of clinically relevant PSA assays.  (+info)

Highly sensitive automated chemiluminometric assay for measuring free human glandular kallikrein-2. (4/204)

BACKGROUND: Human glandular kallikrein (hK2) is a serine protease that has 79% amino acid identity with prostate-specific antigen (PSA). Both free hK2 and hK2 complexed to alpha1-antichymotrypsin (ACT) are present in the blood in low concentrations. We wished to measure hK2 in serum with limited contribution from hK2-ACT for the results. METHODS: We developed an automated assay for hK2 with use of a select pair of monoclonal antibodies. The prototype assay was implemented on a Beckman Coulter ACCESS(R) analyzer. RESULTS: The detection limit of the assay was 1.5 ng/L, the "functional sensitivity" (day-to-day CV <15%) was <4 ng/L, cross-reactivity with PSA and PSA-ACT was negligible, and cross-reactivity with hK2-ACT was 2%. After surgical removal of prostate glands, serum hK2 was <7 ng/L and was <15 ng/L in most healthy women. The median serum concentration of hK2 in healthy men without prostate cancer was 26 ng/L. The median concentration of hK2 was 72 ng/L for men having prostate cancer with lower Gleason scores compared with 116 ng/L for men with more advanced cancer. The concentration of hK2 correlated weakly with PSA, with the mean hK2 concentrations generally 30- to 80-fold lower than PSA concentrations. CONCLUSION: The availability of a robust, high sensitivity automated assay for hK2 should facilitate further investigations of the role of hK2 measurements in the management of patients with prostate disease.  (+info)

Measurement of the complex between prostate-specific antigen and alpha1-protease inhibitor in serum. (5/204)

BACKGROUND: Prostate-specific antigen (PSA) occurs in serum both free and in complex with protease inhibitors. The complex with alpha1-antichymotrypsin (ACT) is the major form in serum, and the proportion of PSA-ACT is higher in prostate cancer (PCa) than in benign prostatic hyperplasia (BPH). PSA also forms a complex with alpha1-protease inhibitor (API) in vitro, and the PSA-ACT complex has been detected in serum from patients with prostate cancer. The aim of the present study was to develop a quantitative method for the determination of PSA-API and to determine the serum concentrations in patients with PCa and BPH. METHODS: The assay for PSA-API utilizes a monoclonal antibody to PSA as capture and a polyclonal antibody to API labeled with a Eu-chelate as a tracer. For calibrators, PSA-API formed in vitro was used. Serum samples were obtained before treatment from 82 patients with PCa, from 66 patients with BPH, and from 22 healthy females. RESULTS: The concentrations of PSA-API are proportional to the concentrations of total PSA. PSA-API comprises 1.0-7.9% (median, 2.4%) of total immunoreactive PSA in PCa and 1.3-12.2% (median, 3.6%) in BPH patients with serum PSA concentrations >4 microgram/L. In patients with 4-20 microgram/L total PSA, the proportion of PSA-API serum is significantly higher in BPH (median, 4.1%) than in PCa (median, 3. 2%; P = 0.02). CONCLUSIONS: The proportion of PSA-API in serum is lower in patients with PCa than in those with BPH. These results suggest that PSA-API is a potential adjunct to total and free PSA in the diagnosis of prostate cancer.  (+info)

Antichymotrypsin interaction with chymotrypsin. Intermediates on the way to inhibited complex formation. (6/204)

Serpins form enzymatically inactive covalent complexes (designated E*I*) with their target proteinases, corresponding most likely to the acyl enzyme that resembles the normal intermediate in substrate turnover. Formation of E*I* involves large changes in the conformation of the reactive center loop (residues P17 to P9') and of the serpin molecule in general. The "hinge" region of the reactive center loop, including residues P10-P14, shows facile movement in and out of beta-sheet A, and this movement appears to be crucial in determining whether E*I* is formed (the inhibitor pathway) or whether I is rapidly hydrolyzed to I* (the substrate pathway). Here, we report stopped-flow and rapid quench studies investigating the pH dependence of the conversion of the alpha1-antichymotrypsin.alpha-chymotrypsin encounter complex, E.I, to E*I*. These studies utilize fluorescent derivatives of cysteine variants of alpha1-antichymotrypsin at the P11 and P13 residues. Our results demonstrate three identifiable intermediates, EIa, EIb, and EIc, between E.I and E*I* and permit informed speculation regarding the nature of these intermediates. Partitioning between inhibitor and substrate pathways occurs late in the process of E*I* formation, most likely from a species occurring between EIc and E*I*.  (+info)

Comparative study of assays for prostate-specific antigen molecular forms. (7/204)

BACKGROUND: The detection of prostate-specific antigen (PSA) molecular forms such as free PSA and PSA-ACT and the use of PSA molecular ratios, especially the percentage of free to total PSA, have been reported to improve the diagnostic accuracy of prostate cancer in the patients with slightly elevated serum PSA values. However, the correlation among the values of serum free PSA or PSA-ACT obtained in various assays remains unclear. METHODS: Serum free PSA and PSA-ACT values were detected with the following assays: Hybritech, DPC, EIKEN, Abbott, Roche and Can-Ag for free PSA and Dainippon, Chugai, EIKEN and Bayer for PSA-ACT. The data obtained with each assay were compared with Hybritech (free PSA) and Dainippon (PSA-ACT) as standards. RESULTS: The free PSA data obtained with the Hybritech, EIKEN, Abbott and Can-Ag kits were similar. The values obtained with the DPC and Roche kits showed a linear regression of y = ax + b with those obtained with the Hybritech, with a b value of zero and an a value of 1.20 and 1.57, respectively. The serum PSA-ACT values detected with the Dainippon and Chugai kits were identical. The equation for converting the data obtained with the EIKEN kits to the Dainippon value was 0.7636 x (EIKEN) + 0.1381. CONCLUSIONS: Serum free PSA and PSA-ACT values obtained with various assays were not necessarily the same. Some kits for the assay of free PSA and PSA-ACT gave the same serum values. The free PSA values obtained with the other kits could be converted using appropriate equations. The gamma-Sm values showed wide variations and were not considered suitable as a measurement of free PSA.  (+info)

Effect of the ratio of free to total prostate-specific antigen on interassay variability in proficiency test samples. (8/204)

BACKGROUND: Up to sevenfold differences were observed between total prostate-specific antigen (PSA) methods for New York State Proficiency Test samples prepared with seminal fluid PSA in human female serum. Because the PSA was mainly in its free form under these conditions, we wanted to determine whether a defined mixture of free and complexed PSA would reduce the interassay differences. METHODS: We prepared a series of five solutions of 60 g/L bovine serum albumin with 10 microgram/L total PSA consisting of varied proportions of free, noncomplexible PSA, and alpha(1)-antichymotrypsin (ACT)-complexed PSA from 0% to 100%. Two hundred seventy laboratories measured the total PSA in these samples, and 16 laboratories also analyzed the samples for free PSA. The results were used to calculate free/total PSA ratios. RESULTS: Interassay CVs for total PSA measurements were approximately 7% at 10-15% free PSA but became gradually larger as the free/total PSA ratio increased. Measured free-PSA concentrations were similar within each sample (mean CV, 12%), and the results were relatively independent of the proportion of free PSA in the samples. Twofold discrepancies between actual and expected ratios were observed with some methods at 100% free PSA and to a lesser degree at 30% free PSA. At 100% free PSA, the relatively higher total-PSA values measured by nonequimolar methods yielded low free/total PSA ratios of 50-60%. In contrast, the lower total PSA values obtained by equimolar methods yielded ratios close to the expected 100%. CONCLUSIONS: Preparing proficiency test samples with a 10:90 mixture of free, noncomplexible PSA:PSA-ACT is a viable alternative to the use of seminal fluid PSA. Furthermore, the method used to measure total PSA may have a substantial impact on the calculated proportion of free PSA and hence may have clinical relevance.  (+info)

Induction of the α<sub>1</sub>-antichymotrypsin gene in the brain associated with TGF-β1 deficiency or systemic administration...Induction of the α<sub>1</sub>-antichymotrypsin gene in the brain associated with TGF-β1 deficiency or systemic administration...
TY - JOUR. T1 - Induction of the α1-antichymotrypsin gene in the brain associated with TGF-β1 deficiency or systemic administration of endotoxin. AU - Saito, Hiroshi. AU - Shultz, Leonard D.. AU - Sinha, Mala. AU - Papaconstantinou, John. PY - 1999/9/24. Y1 - 1999/9/24. N2 - We report that mRNA levels for α1-antichymotrypsin (ACT), a component of β-amyloid plaques in Alzheimers disease, are significantly increased in the brains of two different mouse models that develop inflammation: (1) acute inflammation caused by intraperitoneal injection with lipopolysaccharide (LPS) and (2) chronic inflammation in knockout mice lacking the anti-inflammatory cytokine transforming growth factor β1 (TGF-β1). While brain mRNA levels for the inflammatory cytokines TNFα, IL-1β, and IL-6 were all elevated in the LPS-injected mice, only the mRNA for IL-1β increased significantly in TGF-β1-deficient mice. The transcription factor C/EBPβ was strongly activated in the brains of both models. These results ...
https://researchexperts.utmb.edu/en/publications/induction-of-the-%CE%B1sub1sub-antichymotrypsin-gene-in-the-brain-asso
Serum alpha-2-macroglobulin, antitrypsin and antichymotrypsin activities in patients receiving treatment with cyclosporine<...
TY - JOUR. T1 - Serum alpha-2-macroglobulin, antitrypsin and antichymotrypsin activities in patients receiving treatment with cyclosporine. AU - Roche, Maya. AU - Kusumanjali, G.. AU - Chinnapu Reddy, G.. AU - Kanagasabhapathy, A. S.. AU - Rao, Pragna. PY - 2006. Y1 - 2006. N2 - Cyclosporine has been reported to function as an inhibitor of the chymotrypsin like activity of proteasome. We hypothesized that the administration of an exogenous proteinase inhibitor may affect the activities of the naturally occurring serum anti proteinases. The aim of this study was to observe the pattern of alteration of serum alpha 2 macroglobulin (AMG), alpha 1- antitrypsin (AT) and alpha 1-antichymotrypsin (ACT) activities in renal transplant patients receiving the immunosuppressive drug, cyclosporine. Patients (97) who had received a single renal allograft were inducted into the study. Subjects were on a twice-daily dosage of cyclosporine capsules. Trough (Co) and two-hour post dose (C 2) cyclosporine levels ...
https://manipal.pure.elsevier.com/en/publications/serum-alpha-2-macroglobulin-antitrypsin-and-antichymotrypsin-acti
No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset...No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset...
No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients.
https://scholars.duke.edu/display/pub716506
Alpha, Antichymotrypsin Synthesis by Alveolar Macrophages And Monocyte-Like Cell Lines | Clinical Science | Portland PressAlpha, Antichymotrypsin Synthesis by Alveolar Macrophages And Monocyte-Like Cell Lines | Clinical Science | Portland Press
G Berman, S L C Woo, D Burnett, R A Stockley; Alpha, Antichymotrypsin Synthesis by Alveolar Macrophages And Monocyte-Like Cell Lines. Clin Sci (Lond) 1 January 1987; 73 (s17): 2P. doi: https://doi.org/10.1042/cs073002P. Download citation file:. ...
https://portlandpress.com/clinsci/article-abstract/73/s17/2P/102880/Alpha-Antichymotrypsin-Synthesis-by-Alveolar
Anti-alpha 1 Antichymotrypsin antibody, prediluted (ab921) ProtocolsAnti-alpha 1 Antichymotrypsin antibody, prediluted (ab921) Protocols
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Abstract 19961: Protein-based Risk Score Increases Prior to Cardiovascular Events and Death in Individuals With Apparently...Abstract 19961: Protein-based Risk Score Increases Prior to Cardiovascular Events and Death in Individuals With Apparently...
Starting with 1130 plasma proteins, we previously derived and then externally validated a 9 protein model (CVD9 [angiopoietin 2, complement C7, α-2 antiplasmin, matrix metalloproteinase 12, α-1 antichymotrypsin complex, growth differentiation factors 11/8, chemokine (C-C motif) ligand 18, angiopoietin related protein 4 and troponin I]) to predict 4-year probability of death, myocardial infarction, stroke and heart failure using SOMAscan proteomic technology in subjects with stable coronary heart disease (CHD). In the current study, we tested whether this proteomic risk score increases within individuals as they approach an event. We applied CVD9 to paired plasma samples from 513 subjects in the Heart and Soul study who were still event free when a second blood sample was taken 4.8 years after the first. There were 139 subjects who had events a median of 2.9 years after their second sample, compared to 374 subjects who did not have events after their second sample (with a median of 4.3 years of ...
http://circ.ahajournals.org/content/132/Suppl_3/A19961
The form and Function of Alpha1 Antichymotrypsin in Plasma and Lung Secretions | Clinical ScienceThe form and Function of Alpha1 Antichymotrypsin in Plasma and Lung Secretions | Clinical Science
Thank you for your interest in spreading the word about Clinical Science.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
http://www.clinsci.org/content/70/s13/28P.1
Amyloid-β peptide, substance P, and bombesin bind to the serpin-enzyme complex receptor<...
TY - JOUR. T1 - Amyloid-β peptide, substance P, and bombesin bind to the serpin-enzyme complex receptor. AU - Joslin, Gregg. AU - Krause, James E.. AU - Hershey, Andrew D.. AU - Adams, Steven P.. AU - Fallon, Robert. AU - Perlmutter, David H.. PY - 1991. Y1 - 1991. N2 - During the formation of an inhibitory complex with neutrophil elastase, α1 antitrypsin (α1 AT) undergoes a structural rearrangement and the resulting α1 AT-elastase complex becomes endowed with chemoattractant activities, mediates an increase in synthesis of α1 AT, and is rapidly cleared from the circulation. In previous studies we have provided evidence that these biological activities involve the recognition of a conformation-specific domain in the α1 AT molecule by a cell surface receptor on human hepatoma HepG2 cells and human monocytes. The receptor has been termed the serpin-enzyme complex (SEC) receptor because it also recognizes complexes of serpins antithrombin III, α1 anti-chymotrypsin, and C1 inhibitor with ...
https://indiana.pure.elsevier.com/en/publications/amyloid-%CE%B2-peptide-substance-p-and-bombesin-bind-to-the-serpin-enz
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Worldwide eventsWorldwide events
This course is designed for Japan resident. Lectures and discussions, workshop are conducted in Japanese. Save up to 10% on this course by becoming an AOCMF Member/Member Plus. If you already have an AOCMF login, click here to upgrade before registering to this course. If you dont have an AOCMF login, create a new account here , and then purchase a membership package before registering to this course. ＜登録用日本語 Manual ＞ https://www.dropbox.com/sh/8uahk4hbnl0or9m/AACt9fvDTTw_Q-76l6JT1dFna?dl=0 ...
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Worldwide eventsWorldwide events
This course is designed for Japan resident. Lectures and discussions, workshop are conducted in Japanese. Save up to 10% on this course by becoming an AOCMF Member/Member Plus. If you already have an AOCMF login, click here to upgrade before registering to this course. If you dont have an AOCMF login, create a new account here , and then purchase a membership package before registering to this course. ＜登録用日本語 Manual ＞ https://www.dropbox.com/sh/8uahk4hbnl0or9m/AACt9fvDTTw_Q-76l6JT1dFna?dl=0 ...
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Xpert search results for Why study icons?start=7780Xpert search results for Why study icons?start=7780
The British Election Study (BES) has been conducted at every UK general election since 1964. Topics surveyed include: voting intentions, political knowledge and voter turnout. This site provides information on the study covering the 2010 UK general elections. It includes details of the researchers, who are based at the University of Essex, their methodology and work. It includes information and links on how to obtain datasets from this study and earlier ones from 2001 onwards. Some historic tech ...
https://www.nottingham.ac.uk/xpert/scoreresults.php?keywords=Why%20study%20icons?start=7780&en&start=360&end=380
AACT | definition of AACT by Medical dictionaryAACT | definition of AACT by Medical dictionary
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Prevention of Cognitive Decline in Alzheimer's Disease by Ingested Interferon Alpha - Tabular View - ClinicalTrials.govPrevention of Cognitive Decline in Alzheimer's Disease by Ingested Interferon Alpha - Tabular View - ClinicalTrials.gov
Inflammatory mechanisms contribute to neurodegeneration in AD. Acute phase proteins such as the antichymotrypsin (a1ACT), pro-inflammatory cytokines IL-6 and IL-1, and activated microglial cells are all associated with neuritic plaques. a1ACT levels are elevated in AD, correlate with cognitive decline and serve as a biological marker of intervention. a1ACT is intimately associated with the 42-AA b peptide (Ab) in filamentous amyloid deposits and stimulates the polymerization of Ab into amyloid filaments. IL-6 is found in AD cortices prior to the onset of neuritic change, serum and stimulated PMNC IL-6 levels are higher in AD, and may induce b-amyloid protein deposition. Microglia, CNS resident inflammatory cells, produce IL-6 within the adult human brain, are IL-1a +, and are a prominent component of the neuritic plaque. Because the pathogenesis of AD appears in part immune mediated, we propose testing directly in humans whether ingested IFN-a can ameliorate AD. Because there is no good model ...
https://clinicaltrials.gov/ct2/show/record/NCT00031018?view=results
Microscopic Description -- Case 276Microscopic Description -- Case 276
Macroscopically, the tumor was of yellow-greyish color and medium consistency. Histologic examination of both the primary and recurrent tumors showed solid nests of tumor cells surrounded by a small rim of connective tissue. The neoplasm consisted of polygonal cells with abundant, eosinophilic, granular cytoplasm and relatively sharp cellular margins. Cytoplasmic granules were distinctly PAS-positive and resistant to diastase digestion. There was remarkable cellular and nuclear polymorphism with hyperchromatic nuclei and prominent nucleoli (Fig. 2).There were small areas of foamy cells and perivascular lymphocytic aggregates. Mitoses were rarely registered. The tumor was moderately vascularized. Frank necrosis was not evident. Immunohistochemically, tumor cells were strongly positive for neuron-specific enolase, S-100 protein, a1-antitrypsin and a1-antichymotrypsin (Fig. 3), but negative for glial fibrillary acidic protein, vimentin, various cytokeratins, melanoma marker HMB 45, chromogranin A, ...
http://path.upmc.edu/divisions/neuropath/bpath/cases/Case65/micro.html
Binding and Uptake of A beta 1-42 by Primary Human Astrocytes In VitroBinding and Uptake of A beta 1-42 by Primary Human Astrocytes In Vitro
article{9714ffdf-1e21-475d-ac0b-daebdc2182ca, abstract = {Clearance of the amyloid-P peptide (A beta) as a remedy for Alzheimers disease (AD) is a major target in on-going clinical trials. In vitro studies confirmed that A beta is taken up by rodent astrocytes, but knowledge on human astrocyte-mediated A beta clearance is sparse. Therefore, by means of flow cytometry and confocal laser scanning microscopy (CLSM), we evaluated the binding and internalization of A beta 1-42 by primary human fetal astrocytes and adult astrocytes, isolated from nondemented subjects (n = 8) and AD subjects (n = 6). Furthermore, we analyzed whether alpha 1-antichymotrypsin (ACT), which is found in amyloid plaques and can influence A beta fibrillogenesis, affects the A beta uptake by human astrocytes. Upon over night exposure of astrocytes to FAM-labeled A beta 1-42 (10 mu M) preparations, (80.7 +/- 17.7)% fetal and (52.9 +/- 20.9)% adult A beta-positive astrocytes (P = 0.018) were observed. No significant difference ...
https://lup.lub.lu.se/search/publication/1443637
IHC techniques - Humpath.com - Human pathology
A A beta 42 abl acid phosphatase ACSM1 actin-general actin-alpha cardiac actin-alpha smooth muscle actin-muscle specific AE1/AE3 (cytokeratin) AF4 AGR2 AKT1 albumin alcian blue ALK alkaline phosphatase ALL1 alpha-1-antichymotrypsin alpha-1-antitrypsin alpha-fetoprotein alpha-lactalbumin AMACR AML1 androgen receptor APC API2-MALT1 Apolipoprotein D arginase1 ATM ...
http://humpath.com/spip.php?rubrique453
Free/total PSA ratio | Radiology Reference Article | Radiopaedia.orgFree/total PSA ratio | Radiology Reference Article | Radiopaedia.org
The free/total PSA ratio (%fPSA) is an additional new parameter used in assessing PSA levels. Some authors 1,2 recommend that men with PSA levels of 4.1 to 10 ng/mL who are not suspected of having prostate cancer by whatever means should undergo ...
https://radiopaedia.org/articles/freetotal-psa-ratio
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Classroom Resources | Gases | AACTClassroom Resources | Gases | AACT
In this demonstration, students will observe a reaction between baking soda and vinegar in the presence of a variety of different heights of lit candles. The initial environment has plenty of oxygen present in order to sustain the candles flame; however the reaction will produce carbon dioxide which will cause the lit candles to extinguish in order of height. Students will analyze and compare the presence of the gases in the container and make determinations about the densities of each.. ...
https://teachchemistry.org/classroom-resources/topics/gases?q%5Bgrade_level_ratings_grade_level_id_eq%5D=2&q%5Bresource_topics_topic_id_in%5D=20
Classroom Resources | Energy & Thermodynamics | AACTClassroom Resources | Energy & Thermodynamics | AACT
In this lab, students will learn that even the smallest spaces can have their own climate. They will create a miniature sized terrarium and will observe how sunlight enters in order to warm the air, and in turn heat the soil and seeds. Condensation will build up in the container and the students can observe the water cycle in action, as well as the growth of the seeds over time.. ...
https://teachchemistry.org/classroom-resources/topics/energy-thermodynamics?q%5Bgrade_level_ratings_grade_level_id_eq%5D=1&q%5Bresource_topics_topic_id_eq%5D=59
2017 AACC2017 AACC
Yashraj Biotechnology is an ISO 13485:2003 certified company. Since 1999, we are engaged in manufacturing of Native & Recombinant antigens. We serve our high quality purified antigens to the worldwide, leading diagnostic companies. We currently manufacture CRP • HBsAg-Ay & Ad • CA 15-3 • CA-125 • CA 72-4 • CA 19-9 • B2M • PSA & PSA-ACT • CEA • AFP • A1M • B2M •CYS-C • PR3 • MPO • D-Dimer • NGAL • PAPP-A • sTfR • Ferritin •KFLC • LFLC • RBP. HE-4 , rec-SLO. Mabs- PSA • CRP • CA 125-3 • HbA1c. ...
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Anti-AACT antibody (ab9374) | AbcamAnti-AACT antibody (ab9374) | Abcam
Rabbit polyclonal AACT antibody. Validated in WB, IHC, sELISA and tested in Human. Cited in 1 publication(s). Immunogen corresponding to full length native protein (purified).
https://www.abcam.com/aact-antibody-ab9374.html
Back Again - Part 6 -Very Very PleasedBack Again - Part 6 -Very Very Pleased
Hello again - the hormone shot is doing its thing - no side effects at all - June 2018 blood work is - - PSA - <0.008 -free PSA - <0.01 - testo...
https://www.healingwell.com/community/default.aspx?f=35&m=4028761&g=4029300
Prostate specific antigen complexed to α-1-antichymotrypsin in patients with intermediate prostate specific antigen levels -...Prostate specific antigen complexed to α-1-antichymotrypsin in patients with intermediate prostate specific antigen levels -...
The authors acknowledge the following members of the Okayama Urological Cancer Collaborating Group; Toyoko Yamato, M.D., Ph.D. (Okayama City Hospital); Michinao Saegusa, M.D., Ph.D. (Hiroshima Citizens Hospital); Toshihiko Asahi, M.D., Ph.D. (Kagawa Prefectural Central Hospital); Bunzo Suyama, M.D., (Mitoyo General Hospital); Tadashi Oeda, M.D., Ph.D. (Onomichi Municipal Hospital); Takanori Murakami, M.D. (National Okayama Hospital); Yoshio Maki, M.D., Ph.D. (Konko Hospital); Teruaki Akaeda, M.D., Ph.D. (Tsuyama Central Hospital); Masatoshi Noda, M.D., Ph.D. (Saint Maria Hospital); Teruhisa Ohashi, M.D., Ph.D. (Okayama Redcross Hospital); and Masahiro Hara, M.D., Ph.D. (Fukuyama Municipal Hospital). ...
http://onlinelibrary.wiley.com/doi/10.1002/cncr.10377/abstract
Population-based screening for prostate cancer by measuring free and total serum prostate-specific antigen in Sweden - Hugosson...Population-based screening for prostate cancer by measuring free and total serum prostate-specific antigen in Sweden - Hugosson...
Stenman UH, Leinonen J, Alfthan H, Rannikko S, Tuhkanen K, Alfthan O. A complex between prostate-specific antigen and α1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostatic cancer: assay of the complex improves clinical sensitivity for cancer. Cancer Res 1991; 51: 222-6 ...
http://onlinelibrary.wiley.com/doi/10.1111/j.1465-5101.2003.04396.x/references?globalMessage=0
ALTA : Award Recipient 2005 Sabina Marija JanciauskieneALTA : Award Recipient 2005 Sabina Marija Janciauskiene
Since 1987 her research has focused on the serpin family of SERine PRoteinase INhibitors, which play important regulatory roles in vivo. They now recognise that the physicochemical properties of the serpin structure that confer protease inhibitor activity also render these proteins sensitive to post-translational modifications (i.e. oxidation, nitrosylation, inter- or intramolecular interactions and non-specific cleavage). These altered forms of inhibitory serpins are detected in tissues and fluids recovered from inflammatory sites, but the important questions of how they are generated, what their biological activities are, and which of them are directly linked to pathologies and/or may be useful markers for characterisation of disease states, remain to be answered. Her objective is to address this challenge, focusing on the role of native (inhibitory) and post-translationally modified (non-inhibitory) forms of Alpha1-Antitrypsin in obstructive pulmonary disease and Alpha1-antichymotrypsin in ...
https://www.alta-awards.com/en/award-recipient-2005-sabina-marija-janciauskiene
An original SERPINA3 gene cluster: Elucidation of genomic organization and gene expression in the Bos taurus 21q24 region | BMC...An original SERPINA3 gene cluster: Elucidation of genomic organization and gene expression in the Bos taurus 21q24 region | BMC...
The superfamily of ser ine p roteinase in hibitors (serpins) is involved in numerous fundamental biological processes as inflammation, blood coagulation and apoptosis. Our interest is focused on the SERPINA3 sub-family. The major human plasma protease inhibitor, α1-antichymotrypsin, encoded by the SERPINA3 gene, is homologous to genes organized in clusters in several mammalian species. However, although there is a similar genic organization with a high degree of sequence conservation, the reactive-centre-loop domains, which are responsible for the protease specificity, show significant divergences. We provide additional information by analyzing the situation of SERPINA3 in the bovine genome. A cluster of eight genes and one pseudogene sharing a high degree of identity and the same structural organization was characterized. Bovine SERPINA3 genes were localized by radiation hybrid mapping on 21q24 and only spanned over 235 Kilobases. For all these genes, we propose a new nomenclature from SERPINA3-1 to
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-9-151
David W. Christianson - Searle Scholars ProgramDavid W. Christianson - Searle Scholars Program
Serpins (serine protease inhibitors) comprise a superfamily of more than forty proteins which are implicated in various regulatory cascades in vivo such as blood coagulation, fibrinolysis, complement activation, matrix proteolysis, and inflammation. Since these 45 kD proteins undergo a massive beta-sheet rearrangement during the course of their biological function, serpins are intriguing from the perspectives of protein folding as well as medical relevance. Antichymotrypsin has been engineered to be an inhibitor of human neutrophil elastase in vitro, and the engineered serpin exhibits antiinflammatory properties in vivo. We have determined the structure of this serpin, and current work focuses on a structure-assisted approach toward engineering the specificity and stability of the active serpin. Additionally, we will determine the structure of the serpin in its complex with a target serine protease, and we will also determine the structures of other members of the serpin superfamily, e.g., those ...
https://www.searlescholars.net/people/david-w-christianson
Selection by phage display of a mustard chymotrypsin inhibitor toxic to pea aphid.<...
TY - JOUR. T1 - Selection by phage display of a mustard chymotrypsin inhibitor toxic to pea aphid.. AU - Ceci, L.R.. AU - Volpicella, M.. AU - Conti, S.. AU - Gallerani, R.. AU - Beekwilder, M.J.. AU - Jongsma, M.A.. PY - 2003. Y1 - 2003. N2 - The mustard trypsin inhibitor, MTI-2, is a potent inhibitor of trypsin with no activity towards chymotrypsin. MTI-2 is toxic for lepidopteran insects, but has low activity against aphids. In an attempt to improve the activity of the inhibitor towards aphids, a library of inhibitor variants was constructed and cloned into the pRlac3 phagemid vector. The library of 9.3 107 independent colonies was created by randomisation of a stretch of five consecutive codons in the reactive site. Repeated selection rounds against bovine trypsin and chymotrypsin allowed the identification of novel, MTI-2 derived, antitrypsin and antichymotrypsin inhibitors. Chy8, the selected variant with highest affinity for bovine chymotrypsin (Ki = 32 nm versus ,1000 nm for the ...
https://research.wur.nl/en/publications/selection-by-phage-display-of-a-mustard-chymotrypsin-inhibitor-to
Protease - WikipediaProtease - Wikipedia
The activity of proteases is inhibited by protease inhibitors.[18] One example of protease inhibitors is the serpin superfamily. It includes alpha 1-antitrypsin (which protects the body from excessive effects of its own inflammatory proteases), alpha 1-antichymotrypsin (which does likewise), C1-inhibitor (which protects the body from excessive protease-triggered activation of its own complement system), antithrombin (which protects the body from excessive coagulation), plasminogen activator inhibitor-1 (which protects the body from inadequate coagulation by blocking protease-triggered fibrinolysis), and neuroserpin.[19] Natural protease inhibitors include the family of lipocalin proteins, which play a role in cell regulation and differentiation. Lipophilic ligands, attached to lipocalin proteins, have been found to possess tumor protease inhibiting properties. The natural protease inhibitors are not to be confused with the protease inhibitors used in antiretroviral therapy. Some viruses, with ...
https://en.wikipedia.org/wiki/E1101
Glial-derived proteins activate cultured astrocytes and enhance beta amyloid-induced glial activation.Glial-derived proteins activate cultured astrocytes and enhance beta amyloid-induced glial activation.
In this study, we focused on four glial proteins that are abundant in amyloid plaques and/or that are known to interact with Abeta: alpha1-antichymotrypsin (ACT), interleukin-1beta (IL-1beta), S100beta, and butyrylcholinesterase (BChE). We examined the ability of these proteins to activate rat cortical astrocyte cultures and to influence the ability of Abeta to activate astrocytes. Treatment of astrocytes with ACT, IL-1beta, or S100beta resulted in glial activation, as assessed by reactive morphology, upregulation of IL-1beta, and production of inducible nitric oxide synthase and nitric oxide. The ability of Abeta to induce astrocyte activation was also enhanced in the presence of each of these three proteins. In contrast, BChE alone did not activate astrocytes and had no effect on Abeta-induced activation ...
http://www.prohealth.com/library/showarticle.cfm?libid=1723
Human Apoptosis Protein Array, 73 Target proteins (HA-APP-PA) - Creative Proteomics
14.3.3 Pan, Acinus, AIF (Apoptosis Inducing Factor), Alpha-1-antichymotrypsin, alpha-1-antitrypsin, ARC, Ask1/MAPKKK5, ATM, BAG-1, Bak, Bax, Bcl10/CIPER/CLAP/mE10, bcl-2a, Bcl-6, bcl-X, bcl-XL, Bim (BOD), Caspase 1, Caspase 2, Caspase 3, Caspase 5, Caspase 6 (Mch 2), Caspase 7 (Mch 3), Caspase 8 (FLICE), Cathepsin D, CD137 (4-1BB), CD14, CD95/Fas, CDK2, CDK4, CDK5, c-fos, CIDE-A, CIDE-B, c-jun, CREB, CREB-Binding Protein, Cytochrome c, D4-GDI, Daxx, DcR1, DcR2/TRAIL-R4/TRUNDD, DFF40 (DNA Fragmentation Factor 40)/CAD, DFF45/ICAD, DR3, DR5, ERK1, ERK2, FADD (FAS-Associated death domain-containing protein), Fas-ligand, FLIP, Granzyme B, Heat Shock Protein 70/hsp70, I-FLICE/CASPER, IGF-1R, IGF-I, I-Kappa-B Kinase b (IKKb), JNK Activating kinase (JKK1), MADD, Mcl-1, Mekk-1, NF kappa B/p50, NF kappa B/p65 (Rel A), p53, PARP, PARP (Poly ADP-Ribose Polymerase), Prohibitin, RAIDD, SODD (Silencer of Death Domain), Survivin, TNF alpha, TNFa, ...
https://www.creative-proteomics.com/product/detail-ha-app-pa_35283.htm
Microglia and Alzheimer Disease
Armstrong RA, Winsper SJ, Blair JA (1995) Hypothesis: is Alzheimers disease a metal_induced immune disorder? Neurodegeneration 4:107_111 Bennett SA, Stevenson B, Staines WA, Roberts DC (1995) Periodic acid_Schiff (PAS)_positive deposits in brain following kainic acid_induced seizures: relationships to fos induction, neuronal necrosis, reactive gliosis, and blood_brain barrier breakdown. Acta Neuropathol Berl 89:126_138 Cras P, Smith MA, Richey PL, Siedlak SL, Mulvihill P, Perry G (1995) Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross_linking in Alzheimer disease. Acta Neuropathol Berl 89:291_295 Das S, Potter H (1995) Expression of the Alzheimer amyloid_promoting factor antichymotrypsin is induced in human astrocytes by IL_1. Neuron 14:447_456 De Simone R, Giampaolo A, Giometto B, Gallo P, Levi G, Peschle C, Aloisi F (1995) The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute ...
http://microglia.net/oldpage/ad.htm
How to get rid of Cholinergic UrticariaHow to get rid of Cholinergic Urticaria
Urticaria cholinergic is another type of the Urticaria that is caused by a certain physical stimulus of some or of the other class. It is classified like physical urticaria, meaning that is caused by a physical stimulus of a certain class. The physical stimulus could be indicated as heat although the real cause is defined as sweating. The study of the activity of the cell of the mast includes Urticaria generally cholinergic because most of the cases of Urticaria cholinergic looks like to critically imply the cells of the mast. The main mediator is the histamina of the serum, that rises in the concentration when an induced test exercise is introduced. This treatment also implies quimiotácticos factors eosinophil and of the neutrophil as well as it tryptase. The levels of the alpha 1-antichymotrypsin diminish, and the use of danazol gives rise to the improvement in the eruption. Due to these results, some have discussed in please proteases like a cause of the histamina that was sent. The skin ...
http://www.depression-guide.com/skin-disorders/cholinergic-urticaria.html
Free PSA ELISA kit | CE-GMP | 818 591 3030, USA.Free PSA ELISA kit | CE-GMP | 818 591 3030, USA.
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Free PSA ELISA kit | CE-GMP | 818 591 3030, USA.Free PSA ELISA kit | CE-GMP | 818 591 3030, USA.
Quality Free PSA ELISA kit from ELISA kits manufacturer and elisa kits supplier: Free PSA ELISA kit, PSA elisa kit, Free PSA ELISA Assay, free psa test. Our kits are FDA, CE and ISO certified.
http://www.rapidtest.com/index.php?i=Free-PSA-ELISA-kit&id=42&cat=9
AGE DEFYING SERUM | BocassyAGE DEFYING SERUM | Bocassy
Unique and highly effective blend of active ingredients in this Age-defying Serum create nourishment for mature and fatigue skin to gain back its visible youthful contours. This Serum works in two directions: in one way it is increasing skins firmness, elasticity and daily level of moisture, thus prolonging skins vitality and good looks, while at the same time reducing the depth of existing lines caused by unavoidable stress or simply by time passing by. Mature and fatigue skin usually have identical background - dryness - and it is precisely why Age-defying serum approaches nourishment of mature skin to reduce already visible signs of time and to help replace, increase and maintain skins qualities of youth. Abundance of active ingredients composed to fit precisely aging skin are presented in a light and natural formula, with plenty of moisture. High intake of probiotics in this Age-defying Serum act to stimulate repair of skins barrier, increase its natural defense and immune system, ...
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Should I have a biopsy? - Healthtopquestions - HTQ
I am 61 y.o. male having frequency urination for years. My Total PSA=4.4 and free PSA 11% ... or just monitor my PSA and do it after six months?
https://qa.healthtopquestions.com/128718/should-i-have-a-biopsy
COMMUNIQUÉS West-GlobeNewswire | Page 1783 | santé logCOMMUNIQUÉS West-GlobeNewswire | Page 1783 | santé log
Abonnement premium. Accédez sans limite aux 30 000 actualités du site et recevez gratuitement chaque semaine, les actus Santé à ne pas manquer !. ...
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Serpins Summary Report | CureHunterSerpins Summary Report | CureHunter
Serpins: A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes. This family includes alpha 1-antitrypsin, angiotensinogen, ovalbumin, antiplasmin, alpha 1-antichymotrypsin, thyroxine-binding protein, complement 1 inactivators, antithrombin III, heparin cofactor II, plasminogen inactivators, gene Y protein, placental plasminogen activator inhibitor, and barley Z protein. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES, and some serpins occur in plants where their function is not known.
http://www.curehunter.com/public/keywordSummaryD015843-Serpins.do
Plus itPlus it
Polymorphonuclear neutrophils (PMN) play an important role in myocardial ischemia/reperfusion (MI/R) injury; however, the role of neutrophilic proteases is less understood. The effects of a novel serine protease inhibitor (serpin), LEX032, were investigated in a murine model of MI (20 min) and R (24 hr) injury in vivo. LEX032 is a recombinant human alpha 1-antichymotrypsin in which six amino acid residues were replaced around the active center with those of alpha-1 protease inhibitor. LEX032 has the ability to inhibit both neutrophil elastase and cathepsin G, two major neutral serine proteases in neutrophils, as well as superoxide generation. LEX032 (25 or 50 mg/kg) administered i.v. 1 min before reperfusion significantly attenuated myocardial necrotic injury evaluated by cardiac creatine kinase loss compared to MI/R rats receiving only vehicle (P , .001). Moreover, cardiac myeloperoxidase activity, an index of PMN accumulation, in the ischemic myocardium was significantly attenuated by LEX032 ...
http://jpet.aspetjournals.org/content/274/3/1246
Access Hybritech® free PSA TestAccess Hybritech® free PSA Test
Access Hybritech® free PSA Test,, PSA exists in multiple forms in the blood. Most is bound to proteins, but some is free-floating. In the early 1990s, it was discovered that measuring the ratio of free to total PSA could furth,medicine,medical supply,medical supplies,medical product
http://www.bio-medicine.org/medicine-products/Access-Hybritech-26reg-3B-free-PSA-Test-10547-1/
Category:Sant Ramon - Wikimedia CommonsCategory:Sant Ramon - Wikimedia Commons
Sant Ramon (it); Sant Ramon (fr); Sant Ramon (eu); Sant Ramon (ast); Sant Ramon (diq); Sant Ramon (vi); Сан-Рамон (ru); Sant Ramon (pt); Sant Ramon (sq); Սան Ռամոն (hy); Sant Ramon (an); Sant Ramon (en); Sant Ramon (ro); Sant Ramon (ms); San Ramón (es); Sant Ramon (hu); Sant Ramon (ceb); Sant Ramon (pl); Sant Ramon (oc); Сан-Рамон (Испания) (tt); Sant Ramon (sv); Sant Ramon (nl); Sant Ramon (war); San Ramón (uz); Sant Ramon (gl); Sant Ramon (ca); Sant Ramon (vec); Сан-Рамон (Испани) (ce) comune spagnolo (it); commune espagnole (fr); kommun (sv); gemeente in Spanje (nl); municipi de Catalunya (ca); муниципалитет в Испании, Каталония, Льейда, Сегарра (ru); település Spanyolországban, Lleida tartományban (hu); localidad de la provincia de Lérida, España (es); concello da provincia de Lleida (gl); komunë në Spanjë (sq); conceyu de la provincia de Lleida (ast); human settlement in Segarra, Ponent, ...
https://commons.wikimedia.org/wiki/Category:Sant_Ramon
AACT Pediatric and Forensic Special Interest Group: The Impact of Substance Abuse on the Pediatric Adolescent Patient
Objectives: Compose a list toxins causing metabolic acidosis and hemodynamic instability Describe therapeutic interventions favoring aerobic metabolismin hemodynamically unstable patients Describe the mechanisms for paracetamol-inducedearly metabolic acidosis Outline the management of the...
https://nacct.digitellinc.com/nacct/sessions/4992/view
Prostate cancer free psa - Prostacet Natural Herbal Prostate Health - Jul 23, 2017Prostate cancer free psa - Prostacet Natural Herbal Prostate Health - Jul 23, 2017
Prostate cancer free psa - PSA: At a Glance | Prostate Specific Antigen. Prostacet provides a comprehensive blend of Vitamins, minerals and standardized herbal extracts designed to support healthy prostate function.
http://prostacet.herbalyzer.com/prostate-cancer-free-psa.html
河南快36号开奖结果:Importance of PSA Test - 河南快3号码推荐选号
河南快36号开奖结果:The total PSA (prostate-specific antigen, prostate-specific antigen) value in serum of normal people is 10.0ng/ml, the probability of prostate cancer is very high. Between 4.0 to ...
http://www.cwjub.com/blog/importance-of-psa-test.html
CONGRES-MEDICAL: Equipement m dical : Prochains Ev nements, congres, conf rences, formations m dicales en medecine et sant :...CONGRES-MEDICAL: Equipement m dical : Prochains Ev nements, congres, conf rences, formations m dicales en medecine et sant :...
Equipement m dical - Prochains Ev nements, congres, conf rences, formations m dicales en medecine et sant - Site de r f rencement et promotions de congres, v nement m dicaux et param dicaux mondiaux
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Capio Santé | Treatment AbroadCapio Santé | Treatment Abroad
We provide the following treatments, operations or tests. Select a treatment area/treatment from the list below for more information and prices (where available):. ...
https://www.treatmentabroad.com/hospitals-clinics/private-hospitals-france-capio-sante-411
Alpha 1-antichymotrypsinAlpha 1-antichymotrypsin
... (symbol α1AC, A1AC, or a1ACT) is an alpha globulin glycoprotein that is a member of the serpin ... Alpha 1-antichymotrypsin inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in ... Alpha-1 antitrypsin, another serpin that is analogous for protecting the body from excessive effects of its own inflammatory ... Alpha 1-antichymotrypsin is also associated with the pathogenesis of Alzheimer's disease as it enhances the formation of ...
https://en.wikipedia.org/wiki/Alpha_1-antichymotrypsin
DNAJC1DNAJC1
2006). "BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4". Biochem. Biophys. Res. Commun ... DNAJC1 has been shown to interact with Alpha 1-antichymotrypsin. GRCh38: Ensembl release 89: ENSG00000136770 - Ensembl, May ... 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. Kroczynska B, Evangelista CM, Samant SS, et al. (2004). "The SANT2 domain of ... 83 (1): 153-67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819. Strausberg RL, Feingold EA, Grouse LH, et al. (2003). " ...
https://en.wikipedia.org/wiki/DNAJC1
DNA polymerase alpha catalytic subunitDNA polymerase alpha catalytic subunit
Tsuda M, Masuyama M, Katsunuma T (December 1986). "Inhibition of human DNA polymerase alpha by alpha 1-antichymotrypsin". ... DNA polymerase alpha catalytic subunit is an enzyme that in humans is encoded by the POLA1 gene. This gene encodes the p180 ... DNA dependent polymerase alpha (Pol α) has been shown to interact with MCM4 and GINS1, Retinoblastoma protein, PARP1 and RBMS1 ... PDBe-KB provides an overview of all the structure information available in the PDB for Human DNA polymerase alpha catalytic ...
https://en.wikipedia.org/wiki/DNA_polymerase_alpha_catalytic_subunit
CMA1CMA1
Mellon MB, Frank BT, Fang KC (2002). "Mast cell alpha-chymase reduces IgE recognition of birch pollen profilin by cleaving ... Caughey GH, Raymond WW, Wolters PJ (2000). "Angiotensin II generation by mast cell alpha- and beta-chymases". Biochim. Biophys ... 1993). "Reaction of human chymase with reactive site variants of alpha 1-antichymotrypsin. Modulation of inhibitor versus ... 286 (1): 163-73. doi:10.1006/jmbi.1998.2462. PMID 9931257. Pereira PJ, Wang ZM, Rubin H, et al. (1999). "The 2.2 A Crystal ...
https://en.wikipedia.org/wiki/CMA1
MST1MST1
Skeel A, Leonard EJ (2001). "alpha 1-Antichymotrypsin is the human plasma inhibitor of macrophage ectoenzymes that cleave pro- ... 1999). "Characterization of free alpha- and beta-chains of recombinant macrophage-stimulating protein". Arch. Biochem. Biophys ... 138 (1-2): 171-4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. Waltz SE, Gould FK, Air EL, et al. (1996). "Hepatocyte ... 200 (1-2): 149-56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. Yoshikawa W, Hara H, Takehara T, et al. ( ...
https://en.wikipedia.org/wiki/MST1
KLK6KLK6
Iwata A, Maruyama M, Akagi T, Hashikawa T, Kanazawa I, Tsuji S, Nukina N (Oct 2003). "Alpha-synuclein degradation by serine ... antichymotrypsin". Clinical Chemistry. 49 (5): 746-51. doi:10.1373/49.5.746. PMID 12709365. Magklara A, Mellati AA, Wasney GA, ... "Purification of human kallikrein 6 from biological fluids and identification of its complex with alpha(1)- ... 1350 (1): 11-4. doi:10.1016/s0167-4781(96)00187-x. PMID 9003450. Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis ...
https://en.wikipedia.org/wiki/KLK6
Protein C inhibitorProtein C inhibitor
The genetic code of protein C inhibitor is similar to alpha 1-antitrypsin and alpha 1-antichymotrypsin. The in vivo half time ... Hayashi S, Wakizaka A (July 1995). "Urinary protein C inhibitor binding region in the A alpha-chain of human fibrinogen". Blood ... Billingsley GD, Walter MA, Hammond GL, Cox DW (February 1993). "Physical mapping of four serpin genes: alpha 1-antitrypsin, ... alpha 1-antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome ...
https://en.wikipedia.org/wiki/Protein_C_inhibitor
Prostate-specific antigenProstate-specific antigen
PSA exists in serum in the free (unbound) form and in a complex with alpha 1-antichymotrypsin; research has been conducted to ... 5 (1): 38-48. doi:10.1016/j.eeus.2006.10.003. ISSN 1871-2592. Carter HB, Pearson JD, Metter EJ, Brant LJ, Chan DW, Andres R, et ... ISBN 978-1-891276-02-6. Catalona WJ, Richie JP, Ahmann FR, Hudson MA, Scardino PT, Flanigan RC, et al. (May 1994). "Comparison ... 154 (2 Pt 1): 407-13. doi:10.1016/S0022-5347(01)67064-2. PMID 7541857. Crawford ED, Schutz MJ, Clejan S, Drago J, Resnick MI, ...
https://en.wikipedia.org/wiki/Prostate-specific_antigen
Tau proteinTau protein
Jensen PH, Hager H, Nielsen MS, Hojrup P, Gliemann J, Jakes R (September 1999). "alpha-synuclein binds to Tau and stimulates ... Tau protein has been shown to interact with: Alpha-synuclein, FYN, Proto-oncogene tyrosine-protein kinase Src S100B, and YWHAZ ... and alpha 1-antichymotrypsin". Proceedings of the National Academy of Sciences of the United States of America. 90 (14): 6825-8 ... 18 (1): 164-77. doi:10.1093/hmg/ddn326. PMC 2644648. PMID 18930955. Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, et ...
https://en.wikipedia.org/wiki/Tau_protein
Amita AggarwalAmita Aggarwal
... alpha-1 anti-chymotrypsin and retinol binding protein identified by proteomics as potential biomarkers for lupus nephritis". ... 18 (1): 6. doi:10.1186/s12969-020-0403-9. PMC 6964050. PMID 31941549. Bhattacharya, S; Yadav, A; Aggarwal, A (8 February 2019 ... Aggarwal, A; Sarangi, AN; Gaur, P (1 March 2017). "Gut microbiome in children with enthesitis-related arthritis in a developing ... Aggarwal, A; Gupta, R; Negi, V; Rajasekhar, L; Misra, R; Chaturvedi, P; Sinha, S (1 May 2017). "Urinary haptoglobin, ...
https://en.wikipedia.org/wiki/Amita_Aggarwal
Chymotrypsin-CChymotrypsin-C
1996). "Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced ... Brecher AS, Yang MP (1998). "Acetaldehyde inhibits chymotrypsin and serum anti-chymotrypsin activity". J. Investig. Med. 46 (4 ... 195 (1-2): 27-39. doi:10.1016/0009-8981(90)90191-T. PMID 2093478. Masson E, Chen JM, Scotet V, et al. (2008). "Association of ... 123 (1): 83-91. doi:10.1007/s00439-007-0459-3. PMID 18172691. S2CID 20466442. Rosendahl J, Witt H, Szmola R, et al. (2008). " ...
https://en.wikipedia.org/wiki/Chymotrypsin-C
SerpinSerpin
The disorder alpha-1 antitrypsin deficiency is one of the most common hereditary diseases. Since the stressed serpin fold is ... The X-ray crystal structures of antithrombin, heparin cofactor II, MENT and murine antichymotrypsin reveal that these serpins ... alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder". The New England Journal of Medicine. 309 (12 ... "Alpha-1-antitrypsin: molecular abnormality of S variant". British Medical Journal. 1 (6002): 130-131. January 1976. doi:10.1136 ...
https://en.wikipedia.org/wiki/Serpin
Platelet-activating factorPlatelet-activating factor
"Synthesis and release of platelet-activating factor is inhibited by plasma alpha 1-proteinase inhibitor or alpha 1- ... antichymotrypsin and is stimulated by proteinases". The Journal of Experimental Medicine. 168 (4): 1293-306. doi:10.1084/jem. ... If the sn-1 was removed then PAF lacked any sort of biological activity. Finally, the sn-3 position of PAF was experimented ... 10 (1): 1-6. doi:10.1385/ENDO:10:1:1. PMID 10403564. S2CID 43840751. Yaras N, Ugur M, Ozdemir S, Gurdal H, Purali N, Lacampagne ...
https://en.wikipedia.org/wiki/Platelet-activating_factor
AACTAACT
See Data sources section Alpha 1-antichymotrypsin, a protein American Academy of Clinical Toxicology American Association of ...
https://en.wikipedia.org/wiki/AACT
Alpha-1 antitrypsinAlpha-1 antitrypsin
"Gene regulation of the serine proteinase inhibitors alpha1-antitrypsin and alpha1-antichymotrypsin". Biochemical Society ... The alpha region can be further divided into two sub-regions, termed "1" and "2". Alpha-1 antitrypsin is the main protein of ... Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded ... Alpha-1 antitrypsin levels in the blood depend on the genotype. Some mutant forms fail to fold properly and are, thus, targeted ...
https://en.wikipedia.org/wiki/Alpha-1_antitrypsin
List of MeSH codes (D12.776)List of MeSH codes (D12.776)
... alpha-crystallin a chain MeSH D12.776.306.366.100.300 - alpha-crystallin b chain MeSH D12.776.306.366.300.100 - beta-crystallin ... steroid 12-alpha-hydroxylase MeSH D12.776.422.220.453.915.737 - steroid 16-alpha-hydroxylase MeSH D12.776.422.220.453.915.748 ... Retinoid X receptor alpha MeSH D12.776.826.701.500.625 - Retinoid X receptor beta MeSH D12.776.826.701.500.750 - Retinoid X ... alpha-macroglobulins See List of MeSH codes (D12.776.395). MeSH D12.776.402.150.100.200 - chimerin 1 MeSH D12.776.402.150. ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776)
Alpha globulinAlpha globulin
The alpha globulins typically have molecular weights of around 93 kDa. Alpha globulins include certain hormones, proteins that ... Haptoglobin Alpha-2u globulin α2-macroglobulin Ceruloplasmin Thyroxine-binding globulin Alpha 2-antiplasmin Protein C Alpha 2- ... Alpha globulins are a group of globular proteins in plasma that are highly mobile in alkaline or electrically charged solutions ... α1-antitrypsin Alpha 1-antichymotrypsin Orosomucoid (acid glycoprotein) Serum amyloid A Alpha 1-lipoprotein ...
https://en.wikipedia.org/wiki/Alpha_globulin
List of MeSH codes (D12.776.124)List of MeSH codes (D12.776.124)
... alpha-macroglobulins MeSH D12.776.124.790.720.100.500 - pregnancy-associated alpha 2-macroglobulins The list continues at List ... immunoglobulin alpha-chains MeSH D12.776.124.486.485.114.619.251 - immunoglobulin d MeSH D12.776.124.486.485.114.619.251.500 - ... immunoglobulin alpha-chains MeSH D12.776.124.790.651.114.619.251 - immunoglobulin d MeSH D12.776.124.790.651.114.619.251.500 - ... immunoglobulin alpha-chains MeSH D12.776.124.486.485.705.500.360 - immunoglobulin delta-chains MeSH D12.776.124.486.485.705. ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.124)
AntithrombinAntithrombin
Turk B, Brieditis I, Bock SC, Olson ST, Björk I (1997). "The oligosaccharide side chain on Asn-135 of alpha-antithrombin, ... alpha 1-antichymotrypsin and MENT. The conformational change most relevant for Factor IXa and Xa inhibition involves the P14 ... alpha 2-antiplasmin and Heparin cofactor II. The physiological target proteases of antithrombin are those of the contact ... 17 (1): 81-86. PMID 6724355. Lane DA, Olds RJ, Boisclair M, Chowdhury V, Thein SL, Cooper DN, Blajchman M, Perry D, Emmerich J ...
https://en.wikipedia.org/wiki/Antithrombin
ProteaseProtease
It includes alpha 1-antitrypsin (which protects the body from excessive effects of its own inflammatory proteases), alpha 1- ... antichymotrypsin (which does likewise), C1-inhibitor (which protects the body from excessive protease-triggered activation of ... ISBN 978-1-4160-2973-1. Rodriguez J, Gupta N, Smith RD, Pevzner PA (January 2008). "Does trypsin cut before proline?". Journal ... 7 (1): 300-305. doi:10.1021/pr0705035. PMID 18067249. Renicke C, Spadaccini R, Taxis C (2013-06-24). "A tobacco etch virus ...
https://en.wikipedia.org/wiki/Protease
Outline of immunologyOutline of immunology
Obligate heterodimers of one alpha and one beta subunits Alpha subunits A1 A2 A3 A4 A5 A6 A7 A8 A9 A10 A11 AD AE AL (CD11a) AM ... Alpha-v beta-3 Alpha-v beta-5 Immunoglobulin superfamily CAMs SynCAMs - Synaptic cell adhesion molecules NCAMs - Neural cell ... Fc-alpha receptors (FcαR) FcαRI (CD89, FCAR) Fcα/μR Fc-epsilon receptors (FcεR) FcεRI - Tetramer: FCER1A / FCER1B / two FCER1G ... reflex Inflammasome Granuloma Acute-phase proteins Amyloid SAP SAA Positive Alpha 1-antichymotrypsin Alpha 1-antitrypsin Alpha ...
https://en.wikipedia.org/wiki/Outline_of_immunology
Serum protein electrophoresisSerum protein electrophoresis
... resulting in a typical elevation in the alpha-2 zone during inflammation. A normal alpha-2 and an elevated alpha-1 zone is a ... Alpha-2 macroglobulin may be elevated in children and the elderly. This is seen as a sharp front to the alpha-2 band. AMG is ... Stevenson, FT; Greene, S; Kaysen, GA (January 1998). "Serum alpha 2-macroglobulin and alpha 1-inhibitor 3 concentrations are ... Alpha-1 antitrypsin has an SG group and thiol compounds may be bound to the protein altering their mobility. A decreased band ...
https://en.wikipedia.org/wiki/Serum_protein_electrophoresis
Evolution of the human oral microbiomeEvolution of the human oral microbiome
... alpha amylase I, hemoglobin, etc. Metabolomics and lipidomic studies are used to determine what metabolic categories (amino ... 27 (1): 11-22. doi:10.1111/j.2041-1014.2011.00630.x. ISSN 2041-1006. PMC 4049603. PMID 22230462. (Use dmy dates from March 2022 ... 85 (1): 90-100. doi:10.1111/prd.12353. ISSN 0906-6713. PMID 33226710. S2CID 227132686. Velsko, Irina M.; Fellows Yates, James A ... 7 (1): 102. doi:10.1186/s40168-019-0717-3. ISSN 2049-2618. PMC 6612086. PMID 31279340. Adler, Christina J; Dobney, Keith; ...
https://en.wikipedia.org/wiki/Evolution_of_the_human_oral_microbiome
No association between the alpha 1-antichymotrypsin A allele and Alzheimer's disease. - Nuffield Department of Population Health
The alpha 1-antichymotrypsin (ACT) A allele was recently associated with Alzheimers disease (AD), and the ACT AA genotype was ... The alpha 1-antichymotrypsin (ACT) A allele was recently associated with Alzheimers disease (AD), and the ACT AA genotype was ... No association between the alpha 1-antichymotrypsin A allele and Alzheimers disease. ... No association between the alpha 1-antichymotrypsin A allele and Alzheimers disease. ...
https://www.ndph.ox.ac.uk/publications/937941
Polbase - Reference: Inhibition of human DNA polymerase alpha by alpha 1-antichymotrypsin.
Inhibition of human DNA polymerase alpha by alpha 1-antichymotrypsin. ... Inhibition of human DNA polymerase alpha by alpha 1-antichymotrypsin. Tsuda M, Masuyama M, Katsunuma T ... alpha 1-Antichymotrypsin (ACT), which is known as an efficient serum ... alpha 1-Antichymotrypsin (ACT), which is known as an ... Furthermore ACT heated at 60 degrees C did not inhibit DNA polymerase alpha, although it could still bind to DNA as well as ...
https://polbase.neb.com/references/4579
Evaluation of Molecular Species of Prostate-Specific Antigen Complexed with Immunoglobulin M in Prostate Cancer and Benign...Evaluation of Molecular Species of Prostate-Specific Antigen Complexed with Immunoglobulin M in Prostate Cancer and Benign...
a) IgM; (b) PSA-IgM; (c) PSA-ACT (alpha-1-antichymotrypsin); (d) fPSA: free PSA. ... "Improvement of liver cancer detection with simultaneous assessment of circulating levels of free alpha-fetoprotein (AFP) and ... Figure 1 Representative PSA-immunogram of pooled human prostate cancer sera. Sephacryl S-300 gel filtration of pooled human PCa ... 1. Introduction. Efforts in the field of biomarker research have pointed to the existence of circulating immune complexes as a ...
https://www.hindawi.com/journals/dm/2013/923819/
Kallikrein 3/PSA Antibody (KLK3/801) (NBP2-44886): Novus BiologicalsKallikrein 3/PSA Antibody (KLK3/801) (NBP2-44886): Novus Biologicals
It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion ... It is predominantly complexed to a liverderived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion ... Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating ... Mouse IgG1 Kappa Isotype Control (P3.6.2.8.1) NBP1-43319-0.5mg ... Primary Antibodies are guaranteed for 1 year from date of ...
https://www.novusbio.com/products/kallikrein-3-psa-antibody-klk3-801_nbp2-44886
Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS | PLOS ONEPlasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS | PLOS ONE
Acute phase reactant alpha 1-antichymotrypsin is increased in cerebrospinal fluid and serum of patients with probable Alzheimer ... accuracy based on alpha-1-macroglobulin, amyloid precursor-like protein 1, keratin 16, orosomucoid 2, and pigment epithelium- ... The urea was diluted to a concentration of 1 M with 50 mM NH4HCO3 and then digested with trypsin (1:50 ratio) at 37°C with ... 1Quadratic effect p-value: crude p-value of the likelihood ratio test comparing the goodness-of-fit between the logistic ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236148
Catalog: Dldevelop - page 1 of 249 - gentaur.comCatalog: Dldevelop - page 1 of 249 - gentaur.com
... page 1 of 249. See full list of products in this category ... Human Alpha-1-Antitrypsin (a1AT) ELISA Kit. Catalog number:DL- ...
https://gentaur.com/categories/Dldevelop/1
Prostate Cancer - Siemens Healthineers NederlandProstate Cancer - Siemens Healthineers Nederland
PSA complexed with alpha-1-antichymotrypsin (ACT) comprises a higher proportion of PSA in men with prostate cancer.3-5 This ... A complex between prostate-specific antigen and alpha-1-antichymotrypsin is the major form of prostate-specific antigen in ... Prostate-specific antigen in human serum occurs predominantly in complex with alpha 1-antichymotrypsin. Clin Chem. 1991;37(9): ... 1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global Cancer Statistics 2018: GLOBOCAN estimates of ...
https://www.siemens-healthineers.com/nl/laboratory-diagnostics/assays-by-diseases-conditions/laboratory-diagnostics-in-oncology/prostate-cancer
Staff Profile - Faculty of Medical Sciences - Newcastle UniversityStaff Profile - Faculty of Medical Sciences - Newcastle University
Involvement of alpha 6/alpha 3 neuronal nicotinic acetylcholine receptors in neuropsychiatric features of Dementia with Lewy ... alpha-internexin is present in the hallmark lesions of neuronal intermediate filament inclusion disease. In: 9th International ... Terzano S, Court JA, Fornasari D, Griffiths M, Spurden DP, Lloyd S, Perry RH, Perry EK, Clementi F. Expression of the alpha 3 ... Both Nicotinic and alpha-Bungarotoxin Receptors are lost from the Human Hippocampal Formation during Aging in particular from ...
https://www.ncl.ac.uk/medical-sciences/people/profile/robertperry.html
Creative Diagnostics Launches Immunohistochemistry Antibodies for Pathology Study - PharmiWeb.comCreative Diagnostics Launches Immunohistochemistry Antibodies for Pathology Study - PharmiWeb.com
Alpha-1-Antichymotrypsin (AACT or ACT) is a protease inhibitor that is proposed to act as an anti-inflammatory agent and ... Another example is Anti-Human A-1-Antichymotrypsin monoclonal antibody. ...
https://www.pharmiweb.com/press-release/2021-12-23/creative-diagnostics-launches-immunohistochemistry-antibodies-for-pathology-study
Elevated alpha<sub>1</sub>-antichymotrypsin serum levels in a subset of nondemented first-degree relatives of Alzheimer's...
Elevated alpha1-antichymotrypsin serum levels in a subset of nondemented first-degree relatives of Alzheimers disease patients ... Elevated alpha1-antichymotrypsin serum levels in a subset of nondemented first-degree relatives of Alzheimers disease patients ... Elevated alpha1-antichymotrypsin serum levels in a subset of nondemented first-degree relatives of Alzheimers disease patients ... Elevated alpha1-antichymotrypsin serum levels in a subset of nondemented first-degree relatives of Alzheimers disease patients ...
https://scholars.mssm.edu/en/publications/elevated-alphasub1sub-antichymotrypsin-serum-levels-in-a-subset-o-2
Frontiers | Nanomedicine: A Promising Way to Manage Alzheimers DiseaseFrontiers | Nanomedicine: A Promising Way to Manage Alzheimer's Disease
Inflammatory biomarkers including C-reactive proteins, interleulin-6, fibrinogen, alpha-1-antichymotrypsin, and other ... Saadullah Khattak1, Yuan-Kun Zhai1,5, En-She Jiang1,6, Meng Zheng7, Shao-Feng Duan1,8, Jian-She Wei1,9, Dong-Dong Wu1,5* and ... FIGURE 1. Figure 1. The lifestyle- and age-related factors involved in the onset of AD. AD, Alzheimers disease; HTN, ... Nazeer Hussain Khan1, Maria Mir2, Ebenezeri Erasto Ngowi1,3, Ujala Zafar4, Muhammad Mahtab Aslam Khan Khakwani1, ...
https://www.frontiersin.org/articles/10.3389/fbioe.2021.630055/full
WHO EMRO | Review: Growing burden of noncommunicable diseases: the contributory role of oral diseases, Eastern Mediterranean...
Antimicrobial periodontal treatment decreases serum C-reactive protein, tumor necrosis factor-alpha, but not adiponectin levels ... antichymotrypsin] increased 3-fold in patients with both CVD and periodontal disease [31]; CRP increases independently in ... Annals of periodontology, 1998, 3(1):108-20.. *Petersen PE et al. The global burden of oral diseases and risks to oral health. ... Annals of periodontology, 2001, 6(1):99-112.. *Jansson H et al. Type 2 diabetes and risk for periodontal disease: a role for ...
https://www.emro.who.int/emhj-volume-15-2009/volume-15-issue-4/review-growing-burden-of-noncommunicable-diseases-the-contributory-role-of-oral-diseases-eastern-mediterranean-region-perspective.html
Calprotectin Plus Panel for Monitoring GI Inflammation - DiagnosTechs, Inc.Calprotectin Plus Panel for Monitoring GI Inflammation - DiagnosTechs, Inc.
In addition to fecal calprotectin, the Calprotectin Plus Panel includes total intestinal sIgA, lysozyme, alpha 1- ... antichymotrypsin, fecal occult blood test (FOBT), and fecal pH assays to provide a comprehensive assessment of inflammation ... 1999;34(1):50-4.. *Lewis JD. The utility of biomarkers in the diagnosis and therapy of inflammatory bowel disease. ... 1 Levels of fecal calprotectin also correlate well with radio-labeled leukocyte scanning, a costly and invasive procedure ...
https://www.diagnostechs.com/2022/09/26/new-calprotectin-plus-panel-for-monitoring-gi-inflammation/
MTMT2: citation listMTMT2: citation list
Effects of noninhibitory alpha-1-antitrypsin on primary human monocyte activation in vitro. (2001) ARCHIVES OF BIOCHEMISTRY AND ... Antichymotrypsin interaction with chymotrypsin - Intermediates on the way to inhibited complex formation. (1999) JOURNAL OF ... How the Serpin alpha(1)-Proteinase Inhibitor Folds. (2012) JOURNAL OF BIOLOGICAL CHEMISTRY 0021-9258 1083-351X 287 15 12425- ... Kinetic dissection of alpha(1)-antitrypsin inhibition mechanism. (2002) JOURNAL OF BIOLOGICAL CHEMISTRY 0021-9258 1083-351X 277 ...
https://m2.mtmt.hu/api/citation/?&sort=related,desc&size=100&cond=externalCitation
Insulin - RMab - Affordable Ihc SolutionsInsulin - RMab - Affordable Ihc Solutions
Alpha-1-Antichymotrypsin - Rabbit Polyclonal. Add to Quote. In Quotelist. In Quotelist ...
https://www.affordableihcinstruments.com/product/insulin-rmab/
Find Research outputs - Keio University
Usefulness of alpha1-antichymotrypsin-PSA complex for predicting bone metastases of prostate cancer. Kikuchi, E., Nakashima, J. ... Usefulness of fecal alpha-1-antitrypsin for detection of gastrointestinal bleeding in patients with gastric cancer. Saikawa, Y. ... Hashimoto, M., Ohkuma, K., Akita, H., Yamada, Y., Nakatsuka, S., Mizuno, R., Oya, M. & Jinzaki, M., 2019 Nov 1, In: Medicine ( ... Mori, S., Yashiro, H., Inoue, M., Takahara, K., Kusaka, M. & Shiroki, R., 2020 Apr 1, In: Acta Radiologica. 61, 4, p. 558-567 ...
https://keio.pure.elsevier.com/en/publications/?showAdvanced=false&allConcepts=true&inferConcepts=true&originalSearch=&improvedLayoutOrganisationUuid=&format=&page=1618&ordering=title&descending=false
PredictAD Alzheimers Disease Presenilin Research - Apolipoprotein E or APOE PCR testing on Amyloid Brain TissuePredictAD Alzheimer's Disease Presenilin Research - Apolipoprotein E or APOE PCR testing on Amyloid Brain Tissue
Human Alpha 1 Antichymotrypsin ELISA Kit. April 22, 2021. 1 min read Kayla ... Human Alpha 1 Antichymotrypsin ELISA Kit Applied Cell Extracellular Matrix Cell Counting Kit - 8 ... peptide thymosin alpha, peptide volume essence ingredients, peptide volume essence premium, peptide volume essence review, ... peptide thymosin alpha, peptide volume essence ingredients, peptide volume essence premium, peptide volume essence review, ...
http://www.predictad.eu
DeCSDeCS
alpha 1-Antichymotrypsin - Preferred Concept UI. M0000778. Scope note. Glycoprotein found in alpha(1)-globulin region in human ... Antichymotrypsin. Tree number(s):. D12.644.861.030. D12.776.124.050.050. D12.776.124.790.106.050. D12.776.377.715.085.050. ... alpha-1-Antichymotrypsine Entry term(s):. Serpin A3. alpha 1 Antichymotrypsin. alpha(1)- ... Glycoprotein found in alpha(1)-globulin region in human serum. It inhibits chymotrypsin-like proteinases in vivo and has ...
https://decs.bvsalud.org/en/ths/resource/?id=27943
Code System Concept
Antichymotrypsin deficiency-alpha-1 (disorder). Code System Preferred Concept Name. Antichymotrypsin deficiency-alpha-1 ( ... Alpha-1-antichymotrypsin deficiency Active Synonym false false 353645010 Antichymotrypsin deficiency-alpha-1 Active Synonym ...
https://phinvads.cdc.gov/vads/ViewCodeSystemConcept.action?oid=2.16.840.1.113883.6.96&code=235909002
Cancer Screening - Hancock Regional HospitalCancer Screening - Hancock Regional Hospital
... alpha-2-macroglobulin, and other acute phase proteins. Besides these complexes, about 30% of the PSA present in blood occurs in ... activity of PSA in blood is inhibited by the irreversible formation of complexes with protease inhibitors such as alpha-1- ... antichymotrypsin, ...
https://www.hancockregionalhospital.org/patient-information/preventative-screenings-labs/cancer-screening/
PHARMAPHARMA
Alpha-Amylase. 7,171. 5. 0.00. -1.00. 0.00. 0.56. Xanthine Oxidase. 8,860. Target. Target. Antithrombin 13,773. 2. 0.00. -1.00 ... Alpha-1 AntiChymotrypsin 1,460. 1. 0.00. -1.00. 0.00. 0.59. Viral Disease. 2,087. Disease. Target. Alpha-Glucosidase. 4,319. 1 ... 1. 0.00. -1.00. 0.00. 0.52. Viral Disease. 2,087. Disease. Target. Platelet Activating Factor. 9,915. 2. 0.00. -1.00. 0.00. ... 1. 0.00. -1.00. 0.00. 0.54. Xanthine Oxidase. 8,860. Target. Target. Calcium Dependent Atpase. 105. 2. 0.00. -0.99. 0.02. 0.62 ...
https://gramener.com/pharmatextanalysis/subtable/?pf%3Arows=100&pf%3Asort=CAT2&pf%3Asort=CAT2&pf%3Asort=-WORD1&pf%3Asort=-WORD1&pf%3Asort=CAT2&pf%3Asort=CAT2&pf%3Asort=WORD2&pf%3Apage=573
Human Genome Epidemiology Literature Finder|Home|PHGKBHuman Genome Epidemiology Literature Finder|Home|PHGKB
Association between alpha-1-antichymotrypsin gene polymorphism and cerebral hemorrhage]. Zhonghua yi xue za zhi 2002 Jul 82 (13 ... A study of alpha1 antichymotrypsin gene polymorphism in Indian stroke patients. Journal of the neurological sciences 2010 Mar ... Is Alpha-1 Antichymotrypsin Gene Polymorphism a Risk Factor for Primary Intracerebral Hemorrhage? A Case-Control Study and Meta ... Association between alpha-1 antichymotrypsin gene A/T polymorphism and primary intracerebral hemorrhage: a meta-analysis. ...
https://phgkb.cdc.gov/PHGKB/searchSummary.action?firstQuery=Hemorrhage+and+ACT&Mysubmit=Search
GlyConnectGlyConnect
Alpha-1-antichymotrypsin / Homo sapiens P01011 # Export GlyConnect protein list related to structure with id 9525 P01011 # id ... taxonomy (1) protein (1) source (1) structure (1) composition (1) disease (0) reference (1) site (1) peptide (1) ... RES 1b:b-dglc-HEX-1:5 2s:n-acetyl 3b:b-dglc-HEX-1:5 4s:n-acetyl 5b:b-dman-HEX-1:5 6b:a-dman-HEX-1:5 7b:x-dglc-HEX-1:5 8s:n- ... a-lgal-HEX-1:5,6:d LIN 1:1d(2+1)2n 2:1o(4+1)3d 3:3d(2+1)4n 4:3o(4+1)5d 5:5o(3+1)6d 6:6o(-1+1)7d 7:7d(2+1)8n 8:5o(6+1)9d 9:9o(-1 ...
https://glyconnect.expasy.org/browser/structures/9525
Pathology Outlines - Plexiform fibrohistiocytic tumorPathology Outlines - Plexiform fibrohistiocytic tumor
Rarely alpha-1-antitrypsin and alpha-1-antichymotrypsin Negative stains. * S100, keratin, CD45, Factor VIII, desmin ...
https://www.pathologyoutlines.com/topic/softtissueplexiformfh.html
Pesquisa | Portal Regional da BVSPesquisa | Portal Regional da BVS
Alpha-1-antichymotrypsin (AACT) has been highly associated with cardiac events. In this study, we proposed incorporating ... A Coronary Artery Disease Monitoring Model Built from Clinical Data and Alpha-1-Antichymotrypsin. ... and Ig heavy constant alpha 1 (IGHA1)307-327 were identified and validated. Serum levels of protein, MDA-modified protein ... Moreover, the removal of DNA on the HRGEC surface by DNAse 1 did not interpose the binding of LN1-3 to HRGEC and the effects of ...
https://pesquisa.bvsalud.org/portal/?lang=pt&q=au:Tsai,+I-Jung
BRAF V600E Stain Kit | Celltechgen LLCBRAF V600E Stain Kit | Celltechgen LLC
DESCRIPTION A monoclonal antibody (VE1) against mutant BRAF (V600E) permits fast assessment of the mutant protein expression throughout a tumor sample in hairy cell leukemia, some melanomas, and some thyroid carcinomas. BRAF mutation is a strong molecular marker of poor prognosis in colorectal carcinoma (CRC), and can be used as evidence of a sporadic mechanism of mismatch repair deficiency.. KIT COMPONENTS (100 reactions) ...
https://celltechgen.com/product/braf-v600e-stain-kit/
High grade intraepithelial neoplasia of prostate is associated with values of prostate specific antigen related parameters...High grade intraepithelial neoplasia of prostate is associated with values of prostate specific antigen related parameters...
Serum prostate specific antigen complexed to alpha 1-antichymotrypsin as an indicator of prostate cancer.. J Urol. ... Total PSA (free and PSA complexed to alpha-1-antichymotrypsin) and free PSA measuring were performed by Chemiluminescent ... TABLE 1: Mean age, prostate volume and total PSA (PSA), free PSA (fPSA), ratio free to total PSA (R fPSA/PSA) and PSA density ( ... FIGURE 1: Comparisons of total PSA (A), free PSA (B), ratio free and total PSA (C), and PSA density (D) among patients with ...
https://www.bjbms.org/ojs/index.php/bjbms/article/view/2551
Thyroxine-Binding Globulin | Harvard Catalyst Profiles | Harvard CatalystThyroxine-Binding Globulin | Harvard Catalyst Profiles | Harvard Catalyst
alpha-2-Antiplasmin. *Angiotensinogen. *Antithrombin Proteins. *Complement C1 Inactivator Proteins. *HSP47 Heat-Shock Proteins ...
https://connects.catalyst.harvard.edu/Profiles/display/Concept/Thyroxine-Binding%20Globulin
BIGG
... alpha 1-Antichymotrypsin/therapeutic use ...
https://sites.bvsalud.org/bigg/en/biblio/?filter=author:Casanova,+Ciro
Alpha1-antichymotrypsinGlycoproteinProtease inhibitorA1ACT2021InhibitionSerum proteinsPatientsAlzheimer'sAcuteProteinsAlbuminProteinGenePredominantlyAssaysHuman1999SerpinsProstate cancerDatasetInhibitoryAntibodiesDiseaseAssociationFormTendTherapyDiseasesRegionIncludeSyndrome
Alpha1-antichymotrypsin1
  • A study of alpha1 antichymotrypsin gene polymorphism in Indian stroke patients. (cdc.gov)
Glycoprotein2
  • Other human serum proteins including serum albumin, alpha 1-acid glycoprotein, alpha 1-antitrypsin, and immunoglobulin G as well as other protease inhibitors such as leupeptin, pepstatin, phenylmethylsulfonyl fluoride, and chymostatin did not affect the activity of DNA polymerase alpha. (neb.com)
  • Glycoprotein found in alpha(1)-globulin region in human serum. (bvsalud.org)
Protease inhibitor3
  • alpha 1-Antichymotrypsin (ACT), which is known as an efficient serum protease inhibitor and is detected in tumor cell nuclei, was found to inhibit the activity of DNA polymerase alpha purified from human stomach adenocarcinoma. (neb.com)
  • It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). (novusbio.com)
  • Alpha-1-Antichymotrypsin (AACT or ACT) is a protease inhibitor that is proposed to act as an anti-inflammatory agent and control immunologic functions. (pharmiweb.com)
A1ACT1
  • A portion of Alzheimer's disease (AD) patients have elevated serum levels of the acute phase reactant α 1ˉ antichymotrypsin(A1ACT) compared to age-matched controls. (mssm.edu)
20213
  • 2021;116(1):17-44. (diagnostechs.com)
  • En este artículo se presentan las recomendaciones sobre el diagnóstico y tratamiento del síndrome de agudización de la enfermedad pulmonar obstructiva crónica (EPOC) (SAE) de GesEPOC 2021. (bvsalud.org)
  • Psychiatry Investigation 2021;18(1):11-18. (psychiatryinvestigation.org)
Inhibition4
  • Reference: Inhibition of human DNA polymerase alpha by alpha 1-antichymotrypsin. (neb.com)
  • Targeting PAI-1 in Cardiovascular Disease: Structural Insights Into PAI-1 Functionality and Inhibition. (mtmt.hu)
  • Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. (embl.de)
  • CrmA rapidly inhibits ICE with an association rate constant (kon) of 1.7 x 10(7) M-1 s-1, forming a tight complex with an equilibrium constant for inhibition (Ki) of less than 4 x 10(-12) M. These data indicate that CrmA is a potent inhibitor of ICE, consistent with the dramatic effects of CrmA on modifying host responses to virus infection. (embl.de)
Serum proteins1
  • In human serum, PSA is primarily complexed with α1-antichymotrypsin, and to a lesser extent with other serum proteins. (ok-shtorm.com)
Patients5
  • 2005) [ 11 ] found that innate immune and amyloidogenic proteins were detected more frequently in the cerebrospinal fluid of patients compared to controls, and that the presence of one or more of a subset of proteins (α-1-macroglobulin, amyloid precursor-like protein 1, keratin 16, orosomucoid 2, and pigment epithelium-derived factor) predicted ME/CFS status with 80% accuracy. (plos.org)
  • A complex between prostate-specific antigen and alpha-1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostatic cancer: Assay of the complex improves clinical sensitivity for cancer. (siemens-healthineers.com)
  • It was observed that patients with AD had significantly higher levels of IL-1β and TGF-β than the patients with MCI and normal controls. (psychiatryinvestigation.org)
  • These results suggest that IL-1β and TGF-β may be useful biological markers for patients with Alzheimer's disease. (psychiatryinvestigation.org)
  • AD increases the suffering and burden of patients and caregivers because of the behavioral and psychological symptoms of dementia (BPSD) and impairment in the activity of practical living [ 1 ]. (psychiatryinvestigation.org)
Alzheimer's3
  • No association between the alpha 1-antichymotrypsin A allele and Alzheimer's disease. (ox.ac.uk)
  • The alpha 1-antichymotrypsin (ACT) A allele was recently associated with Alzheimer's disease (AD), and the ACT AA genotype was reported to be more frequent in AD subjects with the apolipoprotein E (APOE) epsilon4 allele. (ox.ac.uk)
  • In this study, the levels of IL-1β, TGF-β and CRP, which are involved in the inflammatory response in Alzheimer's disease and its mild cognitive impairment (MCI), were measured and analyzed. (psychiatryinvestigation.org)
Acute1
  • The proteolytic activity of PSA in blood is inhibited by the irreversible formation of complexes with protease inhibitors such as alpha-1-antichymotrypsin, alpha-2-macroglobulin, and other acute phase proteins. (hancockregionalhospital.org)
Proteins1
  • Identification and characterization of alpha-I-proteinase inhibitor from common carp sarcoplasmic proteins. (mtmt.hu)
Albumin2
  • The best products, quick delivery Active Human PAI-1 Functional Assay ELISA Kit for Non Plasma Samples, Albumin, Dog Plasma, Albumin, Dog Plasma products, high quality. (cleaverplas.com)
  • The absolute ranges for total protein, albumin, and gamma (γ) globulins in the black rhinoceros are similar to those of domestic mammals, however, the albumin to globulin ratio and alpha (α) globulins tend to be lower while the beta (β) globulins tend to be higher in the black rhinoceros than in domestic mammals. (vin.com)
Protein1
  • Potential of Protein-based Anti-metastatic Therapy with Serpins and Inter alpha-Trypsin Inhibitors. (mtmt.hu)
Gene3
  • Association between alpha-1-antichymotrypsin gene polymorphism and cerebral hemorrhage]. (cdc.gov)
  • Alpha-1 antichymotrypsin gene signal peptide a/t polymorphism and primary intracerebral hemorrhage. (cdc.gov)
  • Is Alpha-1 Antichymotrypsin Gene Polymorphism a Risk Factor for Primary Intracerebral Hemorrhage? (cdc.gov)
Predominantly1
  • Prostate-specific antigen in human serum occurs predominantly in complex with alpha 1-antichymotrypsin. (siemens-healthineers.com)
Assays1
  • In addition to fecal calprotectin, the Calprotectin Plus Panel includes total intestinal sIgA, lysozyme, alpha 1-antichymotrypsin, fecal occult blood test (FOBT), and fecal pH assays to provide a comprehensive assessment of inflammation present in the GI tract. (diagnostechs.com)
Human2
  • Another example is Anti-Human A-1-Antichymotrypsin monoclonal antibody. (pharmiweb.com)
  • We reported previously that human interleukin-1 beta converting enzyme (ICE) is regulated by the CrmA serpin encoded by cowpox virus. (embl.de)
19991
Serpins1
  • Inhibitory serpins comprise several alpha-helix and beta-strands together with an external reactive centre loop (RCL) containing the active site recognised by the target enzyme. (embl.de)
Prostate cancer3
  • They include biomarker-immunoglobulin M (IgM) complexes, which have been found in several neoplastic diseases, such as colorectal, liver, and prostate cancer [ 1 - 3 ]. (hindawi.com)
  • 1 Siemens Healthineers offers a full menu of Prostate Specific Antigen (PSA) tests that aid in the detection, monitoring and management of prostate cancer. (siemens-healthineers.com)
  • PSA complexed with alpha-1-antichymotrypsin (ACT) comprises a higher proportion of PSA in men with prostate cancer. (siemens-healthineers.com)
Dataset1
  • The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE [ 1 ] partner repository with the dataset identifier PXD016622. (plos.org)
Inhibitory1
  • It was therefore concluded that the inhibitory action of ACT on DNA polymerase alpha was a direct phenomenon unrelated to its protease inhibitory or DNA binding activities. (neb.com)
Antibodies1
  • Primary Antibodies are guaranteed for 1 year from date of receipt. (novusbio.com)
Disease6
  • Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease of unknown cause that affects up to 2.5 million people in the USA alone [ 1 ]. (plos.org)
  • The disease is defined by persistent fatigue lasting longer than six months, post-exertional malaise, unrefreshing sleep, and either cognitive dysfunction or orthostatic intolerance [ 1 ]. (plos.org)
  • Heart disease, stroke, cancer, diabetes and chronic respiratory disease are the leading causes of death in every region of the world [1]. (who.int)
  • 1 Levels of fecal calprotectin also correlate well with radio-labeled leukocyte scanning, a costly and invasive procedure formerly used to assess active intestinal inflammation in Crohn's disease. (diagnostechs.com)
  • 1. Explanation of the Test Canine brucellosis is an infectious disease caused by bacteria of the genus Brucella canis. (predictad.eu)
  • Taking into account nomenclature, this disease should be differentiated from adenoid cystic carcinomas (ACCs), which-although histologically similar[1, 2, 3, 4, 5, 6] and are also often described as cylindromas-categorically fall under the larger umbrella of salivary gland neoplasms. (medscape.com)
Association1
  • Cet article examine les connaissances actuelles sur la charge des maladies bucco-dentaires et systémiques et leur association, et met en lumière le manque d'information et de recherche dans la Région de la Méditerranée orientale et les autres pays en développement. (who.int)
Form1
  • The major form of PSA is believed to be enveloped by alpha-2 macroglobulin. (cdc.gov)
Tend1
  • 2 flanking elements that tend to include some alpha helix. (iiab.me)
Therapy1
  • Clinical studies of lumacaftor + ivacaftor (combo therapy) produced better FEV1 (forced expiratory volume in 1 second) improvements than ivacaftor alone, without further improvement in sweat chloride results. (stanford.edu)
Diseases1
  • 1,3-8,12 This technique could be particularly beneficial when applied to health monitoring in the black rhinoceros ( Diceros bicornis ), a species which is predisposed to a number of diseases in captivity, the etiologies of which are not yet fully understood. (vin.com)
Region1
  • Precipitation by electrophoresis is in the alpha region. (nih.gov)
Include1
  • They include alpha 1-macroglobulins and alpha 2-macroglobulins. (nih.gov)
Syndrome2
  • Mutations in fibrillin-1 cause congenital scleroderma: stiff skin syndrome. (musc.edu)
  • 3, 10] CYLD cutaneous syndrome is new nomenclature proposed to cover inheritable CYLD germline mutations, grouping together Brooke-Spiegler syndrome (BSS), familial cylindromatosis, and multiple familial trichoepithelioma 1. (medscape.com)
Evaluation of Molecular Species of Prostate-Specific Antigen Complexed with Immunoglobulin M in Prostate Cancer and Benign...
Evaluation of Molecular Species of Prostate-Specific Antigen Complexed with Immunoglobulin M in Prostate Cancer and Benign... (hindawi.com)
Catalog: Dldevelop - page 1 of 249 - gentaur.com
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Creative Diagnostics Launches Immunohistochemistry Antibodies for Pathology Study - PharmiWeb.com
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WHO EMRO | Review: Growing burden of noncommunicable diseases: the contributory role of oral diseases, Eastern Mediterranean...
WHO EMRO | Review: Growing burden of noncommunicable diseases: the contributory role of oral diseases, Eastern Mediterranean... (emro.who.int)
Insulin - RMab - Affordable Ihc Solutions
Insulin - RMab - Affordable Ihc Solutions (affordableihcinstruments.com)
Product test - Affordable Ihc Solutions
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P53 - MMab - Affordable Ihc Solutions
P53 - MMab - Affordable Ihc Solutions (affordableihcinstruments.com)
Find Research outputs - Keio University
Find Research outputs - Keio University (keio.pure.elsevier.com)
PredictAD Alzheimer's Disease Presenilin Research - Apolipoprotein E or APOE PCR testing on Amyloid Brain Tissue
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Pathology Outlines - Plexiform fibrohistiocytic tumor
Pathology Outlines - Plexiform fibrohistiocytic tumor (pathologyoutlines.com)
CDK4 Stain Kit | Celltechgen LLC
CDK4 Stain Kit | Celltechgen LLC (celltechgen.com)
Free support files, msds sheets (each product pdf format} | scytek laboratories
Free support files, msds sheets (each product pdf format} | scytek laboratories (scytek.com)
High grade intraepithelial neoplasia of prostate is associated with values of prostate specific antigen related parameters...
High grade intraepithelial neoplasia of prostate is associated with values of prostate specific antigen related parameters... (bjbms.org)
Thyroxine-Binding Globulin | Harvard Catalyst Profiles | Harvard Catalyst
Thyroxine-Binding Globulin | Harvard Catalyst Profiles | Harvard Catalyst (connects.catalyst.harvard.edu)
1
1 (forums.phoenixrising.me)
Complete Psa Human Elisa Kit - Ok-Shtorm-Blog
Complete Psa Human Elisa Kit - Ok-Shtorm-Blog (ok-shtorm.com)
Immunochemistry and Molecular Biology in Cytological Diagnosis | Basicmedical Key
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Gentaur Antibodies - Gentaur Human Antibodies - Page 9 - Receptors Molecular BV
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Prostate-Specific Antigen Testing: Overview, Physiologic Characteristics of PSA, Other Prostate Cancer Markers
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