Alopecia Areata: Loss of scalp and body hair involving microscopically inflammatory patchy areas.Alopecia: Absence of hair from areas where it is normally present.Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).Hair Follicle: A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.Minoxidil: A potent direct-acting peripheral vasodilator (VASODILATOR AGENTS) that reduces peripheral resistance and produces a fall in BLOOD PRESSURE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)Dermoscopy: A noninvasive technique that enables direct microscopic examination of the surface and architecture of the SKIN.Hair: A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.Mice, Inbred C3HTrichotillomania: Compulsion to pull out one's hair.Autoimmune Diseases: Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.Inosine Pranobex: An alkylamino-alcohol complex of inosine used in the treatment of a variety of viral infections. Unlike other antiviral agents, it acts by modifying or stimulating cell-mediated immune processes rather than acting on the virus directly.CyclobutanesFluocinonide: A topical glucocorticoid used in the treatment of ECZEMA.Eyebrows: Curved rows of HAIR located on the upper edges of the eye sockets.Clobetasol: A derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.Anthralin: An anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.Coal Tar: A by-product of the destructive distillation of coal used as a topical antieczematic. It is an antipruritic and keratoplastic agent used also in the treatment of psoriasis and other skin conditions. Occupational exposure to soots, tars, and certain mineral oils is known to be carcinogenic according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985) (Merck Index, 11th ed).Electronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Food Dispensers, Automatic: Mechanical food dispensing machines.Editorial Policies: The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Postal Service: The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Tinea Capitis: Ringworm of the scalp and associated hair mainly caused by species of MICROSPORUM; TRICHOPHYTON; and EPIDERMOPHYTON, which may occasionally involve the eyebrows and eyelashes.Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Emaciation: Clinical manifestation of excessive LEANNESS usually caused by disease or a lack of nutrition (MALNUTRITION).Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)Scleritis: Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.Dextrocardia: A congenital defect in which the heart is located on the right side of the THORAX instead of on the left side (levocardia, the normal position). When dextrocardia is accompanied with inverted HEART ATRIA, a right-sided STOMACH, and a left-sided LIVER, the combination is called dextrocardia with SITUS INVERSUS. Dextrocardia may adversely affect other thoracic organs.Social Media: Platforms that provide the ability and tools to create and publish information accessed via the INTERNET. Generally these platforms have three characteristics with content user generated, high degree of interaction between creator and viewer, and easily integrated with other sites.Blogging: Using an INTERNET based personal journal which may consist of reflections, comments, and often hyperlinks.Bacteroides: A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.Microbiota: The full collection of microbes (bacteria, fungi, virus, etc.) that naturally exist within a particular biological niche such as an organism, soil, a body of water, etc.Metagenome: A collective genome representative of the many organisms, primarily microorganisms, existing in a community.Gastrointestinal Tract: Generally refers to the digestive structures stretching from the MOUTH to ANUS, but does not include the accessory glandular organs (LIVER; BILIARY TRACT; PANCREAS).Janus Kinases: A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.Narration: The act, process, or an instance of narrating, i.e., telling a story. In the context of MEDICINE or ETHICS, narration includes relating the particular and the personal in the life story of an individual.BooksFood Hypersensitivity: Gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food.Cryotherapy: A form of therapy consisting in the local or general use of cold. The selective destruction of tissue by extreme cold or freezing is CRYOSURGERY. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Cryosurgery: The use of freezing as a special surgical technique to destroy or excise tissue.Oral Medicine: A branch of dentistry dealing with diseases of the oral and paraoral structures and the oral management of systemic diseases. (Hall, What is Oral Medicine, Anyway? Clinical Update: National Naval Dental Center, March 1991, p7-8)
Contribution of interleukin 1beta and KM loci to alopecia areata. (1/140)
Alopecia areata is a common skin disease in which proinflammatory cytokines such as IL-1beta may play a pathogenic role. In this study, we examined the distribution of genotypes of an IL-1beta single base change polymorphism at position +3953 in patients with alopecia areata. The distribution of immunoglobulin kappa light chain (KM) genotypes was similarly examined. The data obtained showed that the IL-1beta and KM loci act cooperatively to significantly increase susceptibility to alopecia areata. (+info)Successful treatment of alopecia areata-like hair loss with the contact sensitizer squaric acid dibutylester (SADBE) in C3H/HeJ mice. (2/140)
A type of hair loss closely resembling human alopecia areata has been described in C3H/HeJ mice. In order to test the assumed analogy with human alopecia areata, we investigated the efficacy of treatment with the contact allergen squaric acid dibutylester. In 12 C3H/HeJ mice with alopecia areata an allergic contact dermatitis was induced and elicited weekly on one side of the back by topical applications of squaric acid dibutylester. Overt hair regrowth was observed only on the treated side of the back in nine of 12 mice. Histopathologic examination revealed a change in the distribution of the inflammatory infiltrate from a dense perifollicular lymphocytic infiltrate around the mid and lower regions of hair follicles in untreated skin to a uniform presence in the upper dermis in treated skin. Immunohistomorphometric studies revealed that treatment with squaric acid dibutylester increased the CD4+/CD8+ ratio from approximately 1:2 in untreated alopecia areata to 1:1 in treated alopecia areata. Additional immunohistochemical investigations showed an aberrant expression of major histocompatibility complex class I, major histocompatibility complex class II and intercellular adhesion molecule 1 on keratinocytes of the mid and lower parts of hair follicles in untreated alopecia areata. In successfully treated skin ectopic major histocompatibility complex class I and II expression was clearly reduced, whereas intercellular adhesion molecule 1 expression showed only minor changes. In conclusion, alopecia areata-like hair loss in C3H/HeJ mice responded to treatment with the contact sensitizer squaric acid dibutylester analogous to human alopecia areata. Moreover, successful treatment changes the aberrant expression of major histocompatibility complex class I and II in a way similar to that observed in human alopecia areata. These observations support the concept that alopecia areata-like hair loss in C3H/HeJ mice can be utilized as an appropriate model for the study of human alopecia areata. (+info)Role of cytotoxic T cells in chronic alopecia areata. (3/140)
Cytokines play a role in alopecia areata. We used immunohistochemical and in situ hybridization studies to demonstrate the persistence of pro-inflammatory as well as apoptotic mechanisms in skin biopsies from patients with chronic alopecia areata. In situ hybridization allows the visualization of the distribution of immunocompetent cells in vivo. We studied skin biopsies from 11 untreated alopecia areata patients and two normal controls. In situ hybridization was performed on frozen sections using 35S-radio-labeled riboprobes, specific for IL-1beta, IL-2, IL-6, INFgamma, and granzyme B mRNA. Immunohistochemistry was carried out using an anti-IL-1beta monoclonal antibody, and a monoclonal antibody directed against the human Fas protein. We demonstrated the presence of cells labeled with IL-1beta, IL-6, INFgamma, and granzyme B antisense probes. Similarly, cells labeled with anti-IL-1beta were found in 10 of 11 cases. The labeled cells were located in the mononuclear peri- and intrafollicular infiltrate. Cells expressing granzyme B were found in close contact with the follicle. Fas positivity was demonstrated in four of four cases at the level of the cytoplasmic membrane of the hair follicle keratinocytes. These results, based on visualizing the labeled cells, demonstrate that pro-inflammatory cytokines are produced by the mononuclear cell infiltrate in close contact with follicles in alopecia areata. Furthermore, they demonstrate for the first time that apoptotic mechanisms involving granzyme B and Fas-Fas ligand pathways may play a major role in the persistence of chronic alopecia areata. (+info)Heavy metal poisoning in glass worker characterised by severe. (4/140)
The paper presents the clinical description of the masticatory organ and biochemical assessment of dental tissue in a patient employed in a glassworks for 20 years. During 12 years the patient has suffered baldness ("Alopecia areata") and atypical extensive and non-healing cutaneous lesions. Dental examination revealed changes typical of chronic poisoning by cadmium and bismuth compounds. (+info)Practical management of hair loss. (5/140)
OBJECTIVE: To describe an organized diagnostic approach for both nonscarring and scarring alopecias to help family physicians establish an accurate in-office diagnosis. To explain when ancillary laboratory workup is necessary to confirm the diagnosis. QUALITY OF EVIDENCE: Current diagnostic and therapeutic interventions for hair loss are based on randomized controlled studies, uncontrolled studies, and case series. MEDLINE was searched from January 1966 to December 1998 with the MeSH words alopecia, hair, and alopecia areata. Articles were selected on the basis of experimental design, with priority given to the most current large multicentre controlled studies. Overall global evidence for therapeutic intervention for hair loss is quite strong. MAIN MESSAGE: The most common forms of nonscarring alopecias are androgenic alopecia, telogen effluvium, and alopecia areata. Other disorders include trichotillomania, traction alopecia, tinea capitis, and hair shaft abnormalities. Scarring alopecia is caused by trauma, infections, discoid lupus erythematosus, or lichen planus. Key to establishing an accurate diagnosis is a detailed history, including medication use, systemic illnesses, endocrine dysfunction, hair-care practices, and family history. All hair-bearing sites should be examined. A 4-mm punch biopsy of the scalp is useful, particularly to diagnose scarring alopecias. Once a diagnosis has been established, specific therapy can be initiated. CONCLUSIONS: Diagnosis and management of hair loss is an interesting challenge for family physicians. An organized approach to recognizing characteristic differential features of hair loss disorders is key to diagnosis and management. (+info)Treatment with an anti-CD44v10-specific antibody inhibits the onset of alopecia areata in C3H/HeJ mice. (6/140)
A murine CD44v10-neutralizing antibody has been reported to impair delayed-type hypersensitivity reactions. Because alopecia areata is characterized by a delayed-type hypersensitivity-like T cell mediated immune response, we addressed the question whether an anti-CD44v10-antibody influences the onset of alopecia areata. Therefore, we used the C3H/HeJ mouse model with the induction of alopecia areata in unaffected mice by the grafting of lesional alopecia areata mouse skin. Six grafted mice were injected (intraperitoneally) with anti-CD44v10, six grafted mice with anti-CD44standard, and six with phosphate-buffered saline only. After 11 wk phosphate-buffered saline injected animals on average had developed alopecia areata on 36.8% of their body. The onset of hair loss was slightly delayed and its extent reduced to 17.2% of their body in anti-CD44standard-treated mice. By contrast, five of six anti-CD44v10-treated mice did not show any hair loss and one mouse developed alopecia areata on only 1% of the body. Immunohistochemical examination revealed a marked reduction of perifollicular CD8+ lymphocytes and, to a lesser degree, CD4+ cells as well as a decreased expression of major histocompatibility complex class I on hair follicle epithelium in anti-CD44v10-treated mice as compared with phosphate-buffered saline or anti-CD44 standard-treated mice. Our data show that anti-CD44v10 is able to inhibit the onset of alopecia areata in C3H/HeJ mice. This might be accomplished by an anti-CD44v10-triggered impairment of immune cell homing (e.g., CD8+ T cells), resulting in a decrease of their number in target tissues. (+info)Interleukin-1 receptor antagonist allele 2 and familial alopecia areata. (7/140)
Alopecia areata affects 1%-2% of the population and is hypothesized to be an autoimmune, organ specific T-cell mediated reaction directed against the human hair follicle. It is characterized by loss of hair in patches (alopecia areata) with progression in some individuals to total loss of scalp hair (alopecia totalis) or to loss of all scalp and body hair (alopecia universalis). The interleukin-1 receptor antagonist (IL-1RN) gene was found to be associated with more severe clinical outcome in several chronic inflammatory diseases, including alopecia areata. The IL-1RN*2 allele was found to be associated with alopecia areata severity in a British case-control study. In this paper, we analyzed alopecia areata probands in a family-based sample (n = 131 parent-offspring trios) to study the association between alleles of the IL-1RN and various phenotypes of alopecia areata. In considering all patients with any form of alopecia areata, no association was found with IL-1RN. IL-1RN*2 allele was not associated with alopecia totalis and alopecia universalis. A borderline association was observed between IL-1RN and patchy alopecia areata but it was not statistically significant (p =0.06). We also observed an association between IL1-RN*1 allele and patchy alopecia areata (p =0.045). (+info)Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdc(scid) mice. (8/140)
Alopecia areata is a tissue restricted autoimmune condition affecting the hair follicle, resulting in hair loss. The goal of this study was to test the hypothesis that the autoantigen of alopecia areata is melanocyte associated. Potential autoantigens were tested in the human scalp explant/Prkd(scid) CB-17 mouse transfer system. Scalp T cells from lesional (bald) alopecia areata scalp were cultured with antigen-presenting cells, and antigen, along with interleukin-2. The T cells were then injected into autologous lesional scalp grafts on SCID mice, and hair regrowth was measured. Hair follicle homogenate was used as an autoantigen control. T cells cultured with melanoma homogenate induced statistically significant reduction in hair growth (p <0.01 by ANOVA). HLA-A2-restricted melanocyte peptide epitopes were then tested with lesional scalp T cells from HLA-A2-positive alopecia areata patients. Melanocyte-peptide-activated T cells significantly reduced the number of hairs regrowing in two experiments with six patients (p <0.001 by ANOVA). Injected scalp grafts showed histologic and immunochemical changes of alopecia areata. The most consistent peptide autoantigens were the Gp100-derived G9-209 and G9-280 peptides, as well as MART-1 (27-35). Melanocyte peptide epitopes can function as autoantigens for alopecia areata. Multiple peptides were recognized, suggesting epitope spreading. (+info)Alopecia areata[edit]. GSE has been found to be associated with alopecia areata (patchy baldness)[44] whereas regrowth did not ... Corazza GR, Andreani ML, Venturo N, Bernardi M, Tosti A, Gasbarrini G (1995). "Celiac disease and alopecia areata: report of a ... Bondavalli P, Quadri G, Parodi A, Rebora A (1998). "Failure of gluten-free diet in celiac disease-associated alopecia areata". ... Bardella MT, Marino R, Barbareschi M, Bianchi F, Faglia G, Bianchi P (2000). "Alopecia areata and coeliac disease: no effect of ...
Gilhar, Amos; Etzioni, Amos; Paus, Ralf (2012-04-19). "Alopecia areata". The New England Journal of Medicine. 366 (16): 1515- ... male alopecia Alopecia scale lupus erythematosus Hidradenitis suppurativa Hair follicles form the basis of the two primary ... Well known diseases of the hair follicle include alopecia or hair loss, hirsutism or excess hair growth and lupus erythematosus ... Well known diseases of the hair follicle include alopecia or hair loss, hirsutism or excess hair growth and lupus erythematosus ...
Female androgenetic alopecia, telogen effluvium and alopecia areata - part II". Anais brasileiros de dermatologia. 87 (6): 884- ... Alkhalifah, A. (2012). "Alopecia Areata Update". Dermatologic Clinics. 31 (1): 93-108. doi:10.1016/j.det.2012.08.010. PMID ... Anagen effluvium Noncicatricial alopecia Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of ... Effluvium can present with similar appearance to alopecia totalis, with further distinction by clinical course, microscopic ...
There is some tentative evidence that anthralin might be useful for alopecia areata. It temporarily stains the skin a yellowy- ... Shapiro, J (Dec 2013). "Current treatment of alopecia areata". The Journal of Investigative Dermatology. Symposium Proceedings ...
ISBN 1-4160-2999-0. Starr, JC; Taneja, N; Brasher, GW (2010). "Relapsing polychondritis following alopecia areata". Case ...
Willemsen, R.; Vanderlinden, J.; Deconinck, A.; Roseeuw, D. (2006). "Hypnotherapeutic management of alopecia areata". Journal ... warts and alopecia areata. Philip D. Shenefelt, a research dermatologist at the University of South Florida School of Medicine ...
Rakowska, A; Slowinska, M; Kowalska-Oledzka, E; Olszewska, M; Czuwara, J; Rudnicka, L (2009). "Alopecia areata incognita: true ... "The role of scalp dermoscopy in the diagnosis of alopecia areata incognita". Journal of the American Academy of Dermatology. 59 ... A new hair disorder described by Antonella Tosti is often referred to as "Tosti alopecia". Her contributions to knowledge about ... Tosti, A; Piraccini, BM; Iorizzo, M; Misciali, C (2005). "Frontal fibrosing alopecia in postmenopausal women". Journal of the ...
Lebwohl M. New treatments for alopecia areata. Lancet. 1997;349(9047):222-3. Kalb RE, Strober B, Weinstein G, Lebwohl M. ...
Published by the National Alopecia Areata Foundation. Retrieved October 29, 2008. [1] Staciana's bio from the 2006-07 USC ... at the National Alopecia Areata Foundation's Teens Conference Camp and has been a spokesperson for the Children's Alopecia ... "The life significance of losing my hair at age 12 from alopecia areata has made me a very strong, determined person." She has ...
Its effect in people with alopecia areata is unclear. Minoxidil is generally well tolerated, but common side effects include ... Hordinsky, M; Donati, A (July 2014). "Alopecia areata: an evidence-based treatment update". American journal of clinical ... It is available as a generic medication and over the counter for the treatment of androgenic alopecia, a form of hair loss, in ... It is effective in helping promote hair growth in both men and women with androgenic alopecia. About 40% of men experience hair ...
She suffers from auto-immune disease alopecia areata. Outdoor 100 metres - 11.34 (+1.0 m/s) (Bydgoszcz 2015) 200 metres - 22.94 ...
Chacín cannot grow hair because of alopecia areata. A joke on Toronto sports radio station Fan 590 that the name Chacín sounds ...
It has also been used successfully in the treatment of alopecia areata. Hypersensitivity, use on face, hypercalcaemia, or ... "Successful Treatment of Alopecia Areata with Topical Calcipotriol". Annals of Dermatology. 24 (3): 341-344. doi:10.5021/ad. ...
Happle R, Van Der Steen P, Perret C. The Renbök phenomenon: An inverse Köebner reaction observed in alopecia areata. Eur J ... Ito, T; Hashizume, H; Takigawa, M (2010). "Contact immunotherapy-induced Renbök phenomenon in a patient with alopecia areata ... Ramot, Y.; Ovcharenko, Y.; Serbina, I.; Zlotogorski, A. (2013). "Renbök phenomenon in an alopecia areata patient with psoriasis ... "Renbök Phenomenon and Contact Sensitization in a Patient with Alopecia Universalis". Archives of Dermatology. 146 (4). doi: ...
... is a form of alopecia areata characterized by the loss of hair in the shape of a wave at the circumference of the head ... "eMedicine - Alopecia Areata : Article by Chantal Bolduc, MD, FRCPC". Retrieved 2007-12-03. Muñoz-Pèrez MA, Camacho FM (1999). " ...
"Canterbury Bulldogs boss Raelene Castle reveals her alopecia areata". Stuff. Retrieved 14 August 2017. ...
Type 1 diabetes is associated with alopecia areata (AA).[18] Type 1 diabetes is also more common in the family members of ... Khan Mohammad Beigi, Pooya (2018), Alopecia Areata, Springer International Publishing, pp. 39-54, doi:10.1007/978-3-319-72134-7 ... Khan Mohammad Beigi, Pooya (2018), "Research Study 2", Alopecia Areata, Springer International Publishing, pp. 103-133, doi: ...
DRB1*04 is associated with increased risk for alopecia areata. DRB1*04:01 is associated with multiple sclerosis, rheumatoid ... 2006). "Investigation of the HLA-DRB1 locus in alopecia areata". European Journal of Dermatology. 16 (4): 363-7. PMID 16935791 ...
"Trichohyalin is a potential major autoantigen in human alopecia areata". Journal of Proteome Research. 9 (10): 5153-63. doi: ...
"I believe I have more to offer the world." Rowsell has alopecia areata, a condition resulting in hair loss. Rowsell was ... Eccles, Louise (21 February 2012). "Courage of a golden girl: How cycling champion became an inspiration to alopecia suffers". ... "London 2012 Olympics: GB cycling champion Joanna Rowsell reveals how alopecia spurred her to gold success". The Daily Telegraph ... External link in ,website= (help) Sleigh, Sophia (24 February 2012). "Alopecia no barrier to Cheam cyclist Joanna Rowsell's ...
"Autoantibodies to DFS70/LEDGF are increased in alopecia areata patients". J. Autoimmun. 23 (3): 257-66. doi:10.1016/j.jaut. ...
"Alopecia Areata: Psoralen With Ultraviolet A Light (PUVA) Therapy-Topic Overview". WebMD. Retrieved 2016-11-10. M. J. Ashwood- ... Psoralen has also been recommended for treating alopecia. Psoralens are also used in photopheresis, where they are mixed with ...
Carrigan has Alopecia Areata, an autoimmune disease that causes hair loss. He has incorporated this into his career, often ...
Shelley WB: The spotted lunula: a neglected nail sign with alopecia areata. J Am Acad Dermatol 1980;2:385.. ... Spotted lunulae is a distinctive change that occurs with alopecia areata. Lunulae James, William; Berger, Timothy; Elston, Dirk ...
He joined the track-and-field team despite having alopecia areata. Graduated from College of Saint Benilde, he is also half- ...
Alopecia *areata. *totalis. *universalis. *Male-pattern hair loss. *Hypertrichosis. *Management. *Trichophilia. * ...
a b c d e f g h i Zoe Diana Draelos (August 30, 2007), Alopecia Areata Archived 2007-12-08 at the Wayback Machine.. MedicineNet ... hair can either grow back or progress to alopecia areata totalis or, in rare cases, alopecia areata universalis.[6] ... Alopecia areata and alopecia barbae have been identified by some as the biblical nethek condition that is part of the greater ... a b c d e f Alopecia Areata at Merck Manual of Diagnosis and Therapy Professional Edition ...
The Australia Alopecia Areata Foundation exists to improve the lives of people living with Alopecia Areata and their families. ...
Alopecia areata is a common disorder that causes hair loss. Explore symptoms, inheritance, genetics of this condition. ... Alopecia areata is a common disorder that causes hair loss. "Alopecia" is a Latin term that means baldness, and "areata" refers ... It is one of many recognized forms of alopecia; alopecia areata is the second most common form after androgenetic alopecia ( ... have also been associated with alopecia areata.. Some of the genetic variations associated with alopecia areata have been ...
Alopecia areata may be hereditary and isnt contagious. ... Alopecia Areata. *Alopecia areata facts. *What is alopecia ... Read about alopecia areata causes, symptoms (balding), diagnosis, and hair loss treatment (shampoo). ... Top Alopecia Areata Related Articles. *. Alopecia Areata (Nails) Picture. Pitting in organized transverse rows giving the nail ... National Alopecia Areata Foundation. Spano, Frank, and Jeff C. Donovan. "Alopecia Areata: Part 1: Pathogenesis, Diagnosis, and ...
Alopecia areata is a form of hair loss thats triggered by your immune system mistakenly viewing hair follicles as threats to ... HealthDay News) -- Alopecia areata is a form of hair loss thats triggered by your immune system mistakenly viewing hair ... home/skin center/ skin a-z list/ health tip: understanding alopecia areata article ... Do certain diseases or conditions raise a persons risk for developing alopecia areata? ...
Alopecia areata, a fairly common disorder of unknown cause characterized by sharply outlined patches of sudden complete ... Other articles where Alopecia areata is discussed: baldness: ... Alopecia areata. dermatology. THIS IS A DIRECTORY PAGE. ... Alopecia areata, a fairly common disorder of unknown cause characterized by sharply outlined patches of sudden complete ...
ALOPECIA AREATA AND STRABISMUS. Br Med J 1922; 2 doi: https://doi.org/10.1136/bmj.2.3229.1001-d (Published 18 November 1922) ...
Alopecia areata is a type of hair loss that affects patches of the scalp. It is usually temporary. Find out what causes it, how ... Alopecia Areata: Causes, Symptoms, and Treatment Alopecia areata is a common autoimmune disorder that can affect anyone, ... What is alopecia areata?. Alopecia areata causes hairless patches on the scalp. ... Alopecia refers to any type of hair loss. In a person with alopecia areata, smooth, round patches of hair loss appear over a ...
National Alopecia Areata Foundation based in San Rafael, California is dedicated to the discovery of a cure or treatment for ... alopecia areata and supporting the conditions victims. It was founded in 1981. Bree Morse, Miss California 2015, based her ...
Serial publication: National Alopecia Areata Newsletter, quarterly--letters from people who have alopecia areata, medical ... The National Alopecia Areata Foundation (NAAF) was established in 1981 as a support network for people who have this disorder, ... The Foundation provides information on alopecia areata, including suggestions for coping with it, cosmetically and ...
Alopecia areata is a common hair loss condition that seems to be related to immune system dysfunction. It appears as well- ... Treatments for Alopecia Alopecia areata (AA) is probably the third most common form of hair loss dermatologists see, after ... Alopecia Areata. In this Article. In this Article In this Article * ... If the alopecia is just limited to the beard area in men, it is called alopecia barbae. ...
... validity to provide scientific evidence of benefit with complementary and alternative medicine therapies for alopecia areata.{ ... The genetic basis of alopecia areata: HLA associations with patchy alopecia areata versus alopecia totalis and alopecia ... Drugs & Diseases , Dermatology , Alopecia Areata Q&A What are nonpharmacologic treatments for alopecia areata?. Updated: Aug 06 ... What are nonpharmacologic treatments for alopecia areata?) and What are nonpharmacologic treatments for alopecia areata? ...
Areata? Below is a list of common natural remedies used to treat or reduce the symptoms of Alopecia+Areata. Follow the links to ... Considering taking a vitamin or supplement to treat Alopecia+ ... 9 results found for Alopecia+Areata. Treatment name. ...
Clinically, alopecia areata can manifest many different patterns. ... Alopecia areata is a recurrent nonscarring type of hair loss ... The genetic basis of alopecia areata: HLA associations with patchy alopecia areata versus alopecia totalis and alopecia ... Alopecia Areata) and Alopecia Areata What to Read Next on Medscape. Related Conditions and Diseases. * Alopecia Areata ... Alopecia Areata Trial Results, Skin Oncology Top EADV Agenda * Alopecia Areata: Which Kids Should You Screen for Thyroid ...
Alopecia areata is an autoimmune condition that causes hair to fall out in round patches. Learn about its symptoms, causes, and ... Alopecia areata in males. Alopecia areata occurs in both men and women, but the loss of hair is likely to be more significant ... How is alopecia areata diagnosed?. A doctor may be able to diagnose alopecia areata simply by looking at the extent of your ... Symptoms of alopecia areata. The main symptom of alopecia areata is hair loss. Hair usually falls out in small patches on the ...
Diagnosing Alopecia Areata in Dogs. Alopecia areata may be easily detected, as you can see the bald spots. However, a vet needs ... Causes of Alopecia Areata. Alopecia areata may be an inherited disease that is more common in certain canine breeds. However, ... Alopecia areata is a condition that manifests through hair loss in patches and can be seen in a single area or can be spread ... Additional Symptoms of Alopecia Areata in Cats. In addition to bald patches you may also be able to identify additional ...
Treatment of alopecia areata with simvastatin/ezetimibe.. Lattouf C1, Jimenez JJ2, Tosti A2, Miteva M2, Wikramanayake TC2, ... Alopecia areata (AA) and treatment with simvastatin/ezetimibe: Experience of 20 patients. [J Am Acad Dermatol. 2016] ... Reply: Alopecia areata treatment with simvastatin/ezetimibe. [J Am Acad Dermatol. 2016] ...
The genetic basis of alopecia areata: HLA associations with patchy alopecia areata versus alopecia totalis and alopecia ... Drugs & Diseases , Dermatology , Alopecia Areata Q&A How is a reticular pattern of alopecia areata characterized?. Updated: Aug ... How is a reticular pattern of alopecia areata characterized?) and How is a reticular pattern of alopecia areata characterized? ... Latanoprost in the treatment of eyelash alopecia in alopecia areata universalis. J Eur Acad Dermatol Venereol. 2010 Apr. 24 (4 ...
Find NATIONAL ALOPECIA AREATA FOUNDATION volunteering opportunities at VolunteerMatch! ... NATIONAL ALOPECIA AREATA FOUNDATION NATIONAL ALOPECIA AREATA FOUNDATION Mission Statement. NAAF supports research to find a ... and educates the public about alopecia areata.. Description. Alopecia areata is a prevalent autoimmune skin disease resulting ... Alopecia areata occurs in males and females of all ages, but onset often occurs in childhood. Over 6.6 million people in the ...
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Alopecia Areata Trial Results, Skin Oncology Top EADV Agenda Alopecia Areata Trial Results, Skin Oncology Top EADV Agenda. ... Alopecia Areata: Who Gets Screened for Thyroid Disease? Alopecia Areata: Who Gets Screened for Thyroid Disease?. Many children ... Alopecia Areata: A Review of Disease Pathogenesis Alopecia Areata: A Review of Disease Pathogenesis. This article offers new ... Alopecia Areata: Current Practices vs. New Directions Alopecia Areata: Current Practices vs. New Directions. Many treatments ...
... topical minoxidil as compared with placebo in 30 patients with alopecia areata and alopecia totalis. The active preparation ... The study confirmed that topical minoxidil will induce new hair growth in alopecia areata but that it is less likely to do so ... Topical minoxidil in the treatment of alopecia areata. Br Med J (Clin Res Ed) 1983; 287 :1015 ... Topical minoxidil in the treatment of alopecia areata.. Br Med J (Clin Res Ed) 1983; 287 doi: https://doi.org/10.1136/bmj. ...
The public meeting is intended to allow FDA to obtain patient perspectives on the impact of alopecia areata, including on daily ... is announcing a public meeting and an opportunity for public comment on Patient-Focused Drug Development for Alopecia Areata. ... FDA is interested in obtaining patient input on the impact of alopecia areata, including on daily life, patient views on ... On September 11, 2017, FDA is conducting a public meeting on Alopecia Areata Patient-Focused Drug Development. ...
Ahmed AM, Barahmani N, Duvic M; National Alopecia Areata Registry. Familial alopecia areata and chronic thrombocytopenia. J Am ... Rodriguez TA, Duvic M; National Alopecia Areata Registry. Onset of alopecia areata after Epstein-Barr virus infectious ... Alopecia areata is the loss of hair in patches that can proceed to loss of all hair (alopecia totalis or universalis). The ... Patients with alopecia areata (AA), both children and adults, who have been diagnosed by a physician with alopecia universalis ...
Alopecia Areata - an easy to understand guide covering causes, diagnosis, symptoms, treatment and prevention plus additional in ... Alopecia areata cannot be prevented. Treatment. Although there is no permanent cure for alopecia areata, there are ways that ... Alopecia areata is a skin disorder that causes hair loss, usually in patches, most often on the scalp. Usually, the bald ... Some people with alopecia areata also have abnormalities in the surface of their fingernails, such as tiny pits or dents, ...
TotalisUniversalisCases of alopecia areataNational Alopecia Areata FoundationPatches of alopecia areataPathogenesis of the alopecia areataRegrowthSymptomsSeen on the scalpAndrogenetic AlopeciaPatchyCannot be curedPatientsGenes underlyiTreatmentsTreatmentCommon autoimmune diseaseKnown as alopeciaPsoriasisClinicalOriginateImmuneFolliclesOnsetPeople
- Alopecia areata usually starts with one or more small, round patches on the scalp and may progress to total scalp hair loss (alopecia totalis) or complete body hair loss (alopecia universalis). (healthcanal.com)
- To address this problem of not being able to predict disease progression, Dr. Christiano and her team looked for a correlation between how many genes (each gene comes in two pairs) people with different severities of alopecia areata carried, and found that people who carried 13-14 genes had disease that did not progress, while those with 16 or more most often progressed to alopecia universalis (total baldness). (healthcanal.com)
- Among all cases of alopecia areata, seven patients were recorded to have the targetoid concentric hair pattern, which seen 2 - 4 weeks after therapy, their ages ranged from 4 to 25 years old with a mean 14.5, all of them were males. (scirp.org)
- According to the National Alopecia Areata Foundation, alopecia areata is a common autoimmune skin disease resulting in the loss of hair on the scalp and elsewhere. (healthcanal.com)
- This research is very exciting as alopecia areata affects a huge number of people worldwide, and there are very few treatments for it - resulting in an enormous unmet medical need," said Vicki Kalabokes, president and CEO of the National Alopecia Areata Foundation , which funded Dr. Christiano's early pilot studies on the genetic basis of alopecia areata. (healthcanal.com)
- All patients showed targetoid polycyclic concentric hair pattern where the new hair growth was arranged in an alternating circles or rings of complete hair regrowth and incompleteor little haïrregrowth in the patches of alopecia areata forming so called targetoid pattern ( Figure 1 and Figure 2 ). (scirp.org)
- The main forms and risk factors of UV-radiation, skin damages by UV-Iight as well as the pathogenesis of the alopecia areata are reviewed. (elsevier.com)
- To screen all cases of treated alopecia areata for hair targetoid regrowth pattern. (scirp.org)
- All cases treated for alopecia areata with IM triamcinolone 20 - 40 mg injection every 2 weeks with topical clobetasone ointment and zinc sulfate 2 mg/kg/day for 2 months, were examined for the targetoid concentric hair regrowth pattern. (scirp.org)
- Targetoid polycyclic concentric hair regrowth pattern is an important phenomenon seen in patients receiving treatment for alopecia areata, which is a good sign of recovery where its etiopathogenesis could not well be elucidated but alternating immunological reactions could explain this targetoid pattern. (scirp.org)
- During attack of alopecia areata, hair involvement occurs in a synchronized way, so in one patch all the hair follicles are affected, but during therapy the hair might regrow in waves, the so called targetoid concentric hair regrowth, and this pattern although is rare but it's well documented in literature. (scirp.org)
- Signs and Symptoms of Alopecia Areata Alopecia areata shows up as bald patches. (curofy.com)
- In alopecia areata, usually hair loss is seen on the scalp, but any body part covered with hair can be affected. (curofy.com)
- It is a natural treatment for men and women suffering from hair loss, also known as Androgenetic alopecia. (avoidinghairloss.com)
- While alopecia areata cannot be cured, the condition can bee managed in order to restore hair growth to a patient. (chicagohairinstitute.com)
- Patients suffering from alopecia areata very often mention a family member suffering from the same condition. (curofy.com)
- A total of seven patients among all patients treated with alopecia areata had targetoid phenomenon, all of them were males and their ages ranged from 4 to 25 years with a mean: 14.5 years. (scirp.org)
- Finding the initial genes underlying alopecia areata is a big step forward, but the nature of the genes is even more exciting," said Angela M. Christiano, Ph.D. , professor of dermatology and genetics & development at Columbia University Medical Center, and lead author of the study. (healthcanal.com)
- Since many of the genes are also implicated in other autoimmune diseases, including rheumatoid arthritis and type 1 diabetes - and treatments have already been developed that target these genes - this discovery may soon lead to new treatments for the 5.3 million Americans suffering from hair loss caused by alopecia areata. (healthcanal.com)
- Homeopathic Treatment for Alopecia Areata Homeopathic treatment is very effective in dealing with alopecia areata. (curofy.com)
- Arsenic Album - Homeopathic Medicine for Alopecia Areata Accompanied by Itching and Burning on the Scalp Arsenic Album is a recommended homeopathic treatment for alopecia areata which appears as circular bald patches along with itching and burning on the scalp. (curofy.com)
- Silicea is a good homeopathic treatment for alopecia areata occuring on the back of the scalp. (curofy.com)
- Alopecia areata is a common autoimmune disease, where there are many topical and systemic therapies, during which hair growth appears in a uniform pattern. (scirp.org)
- The loss of hair in patches is known as alopecia areata. (curofy.com)
- When alopecia areata appears in the beard, it is known as alopecia areata barbae.Homeopathy is an advanced science and treats many diseases of autoimmune origin including alopecia areata. (curofy.com)
- For years, alopecia areata was thought to be related to psoriasis because both are inflammatory diseases where T cells attack the skin. (healthcanal.com)
- For this reason, psoriasis drugs have been tested in clinical trials for alopecia areata, but without much success. (healthcanal.com)
- And since drugs are already in development that target these pathways - because they are being tested to treat rheumatoid arthritis, type 1 diabetes and other diseases where the NKG2D receptor is involved - we may soon be able to test these drugs in clinical trials for alopecia areata. (healthcanal.com)
- Homeopathic medicines for treating alopecia areata originate from natural sources which exclude any risk of side effects. (curofy.com)
- Homeopathic remedies for alopecia areata affect our body by optimizing our immune system. (curofy.com)
- Alopecia areata is an autoimmune disease, meaning that the body's own immune system attacks the hair follicles. (chicagohairinstitute.com)
- Normally, ULBP3 is not present in hair follicles, but the ULBP3 proteins are abundant in hair follicles affected by alopecia areata. (healthcanal.com)
- Unlike other kinds of hair loss, alopecia areata is a reversible hair loss as the follicles ( a structure that encloses the root of the hair) of hair are not damaged. (curofy.com)
- Among the eight genes, one stands out for its potential role in the onset of alopecia areata. (healthcanal.com)
- 3. Baryta Carb, Lycopodium, and Silicea - Homeopathic Medicines for Alopecia Areata in Young People The most prominently indicated homeopathic medicines for alopecia areata in young people are Baryta Carb, Lycopodium, and Silicea. (curofy.com)
- Anyone can develop alopecia areata, but it is more common in people who have had relatives who suffered from the condition. (chicagohairinstitute.com)