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Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50)
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Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
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Unctuous combustible substances that are liquid or easily liquefiable on warming, and are soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. Depending on their behavior on heating, they are volatile or fixed. (Dorland, 28th ed)
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Oils which evaporate readily. The volatile oils occur in aromatic plants, to which they give odor and other characteristics. Most volatile oils consist of a mixture of two or more TERPENES or of a mixture of an eleoptene (the more volatile constituent of a volatile oil) with a stearopten (the more solid constituent). The synonym essential oils refers to the essence of a plant, as its perfume or scent, and not to its indispensability.
Estrogens
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
Steroids
A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
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Receptors, Estrogen
Estrogen Receptor alpha
Estradiol
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Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.
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Alberta
A province of western Canada, lying between the provinces of British Columbia and Saskatchewan. Its capital is Edmonton. It was named in honor of Princess Louise Caroline Alberta, the fourth daughter of Queen Victoria. (From Webster's New Geographical Dictionary, 1988, p26 & Room, Brewer's Dictionary of Names, 1992, p12)
British Columbia
A province of Canada on the Pacific coast. Its capital is Victoria. The name given in 1858 derives from the Columbia River which was named by the American captain Robert Gray for his ship Columbia which in turn was named for Columbus. (From Webster's New Geographical Dictionary, 1988, p178 & Room, Brewer's Dictionary of Names, 1992, p81-2)
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Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, A and B. Both are induced by estrogen and have short half-lives.
The effect of synthetic gestagens on progesterone formation in vitro in human placenta of early pregnancy. (1/5)
Villous tissue from 26 placentae of 7-17 weeks was incubated with radioactive pregnenolone alone and with pregnenolone in the presence of progesterone and 9 synthetic gestagenic steroids and the progesterone formation was measured after 30 min. When progesterone was present in a concentration of 31 or 310 mumol/1 the conversion rate of labelled pregnenolone to progesterone was reduced to 88.6 and 82.2% of that of the respective control incubations. Dydrogesterone, allyloestrenol, lynoestrenol and norethynodrel under similar conditions did not inhibit the formation of progesterone. The inhibitory effects of megoestrol acetate, medroxyprogesterone acetate and norgestrel were close to that of progesterone. Norethisterone and methyloestrenolone were the most effective inhibitors of progesterone formation: when incubated in an equimolar concentration (35 mumol/1) with pregnenolone (50 microgram) the progesterone formation was reduced to 60.0-62.7% and 29.1-34.0% respectively of that of the respective control experiments. (+info)Recovery of serum prostate specific antigen value after interruption of antiandrogen therapy with allylestrenol for benign prostatic hyperplasia. (2/5)
Decrease in serum prostate specific antigen (PSA) concentration is inevitably associated with antiandrogen therapy for benign prostatic hyperplasia (BPH), and might mask the presence of prostate cancer or delay its diagnosis. To determine the appropriate timepoint for determination of correct PSA value, we sequentially measured serum PSA and testosterone levels after discontinuation of antiandrogen therapy for BPH. With informed consent, 12 patients (72.8 +/- 12.2* years old) with BPH were treated with allylestrenol 50 mg/day for 4 months. Serum testosterone and PSA concentrations were determined before and just after treatment, as well as every month after treatment up to 3 months. After treatment with allylestrenol for 4 months, mean serum testosterone and PSA levels were significantly decreased from 408 +/- 136* to 87.9 +/- 76.2* ng/dl, and from 2.81 +/- 0.87* to 2.04 +/- 0.82* ng/ml, respectively. The mean serum PSA level recovered to the pretreatment level within 2 months and mean serum testosterone concentration within one month after discontinuation of administration. In conclusion, during treatment of BPH with antiandrogen allylestrenol, a two-month washout is adequate for determination of correct PSA value (*: M +/- SD). (+info)A case of suspected teratogenic holoprosencephaly. (3/5)
A case of holoprosencephaly is reported in which the mother was prescribed high doses of oestroprogestins during the first 5 months of the pregnancy. Investigation of the family failed to reveal any sign of physical abnormality. A normal karyotype was detected in the proband. The authors suggest that this case may shed some light on the normal and abnormal way in which embryonic fields develop. (+info)Effects of a new non-steroidal 5 alpha-reductase inhibitor, FK143, on the prostate gland in beagle dogs. (4/5)
FK143 (4-[3-[3-[bis(4-isobutylphenyl)methylamino]benzoyl]-1H-indol-1-yl] - butyric acid) is a new non-steroidal inhibitor of steroid 5 alpha-reductase (5 alpha-reductase). The effects of FK143 on prostate size and histopathology of mature male beagle dogs were investigated and compared with those of finasteride (a steroidal 5 alpha-reductase inhibitor), and allylestrenol and chlormadinone acetate (CMA) (androgen receptor antagonists). FK143 was orally administered to the dogs daily for 12 weeks. At doses of 10 and 32 mg/kg, FK143 significantly reduced prostate volume to about 60% of the initial value, and dogs treated with FK143 showed a dose-dependent glandular epithelial atrophy in the prostate. FK143 showed no abnormal changes in organ weights and histopathology of the adrenal, testis, pituitary and liver. The degree of prostate reduction in the dogs treated with FK143 (10 and 32 mg/kg) was almost the same as that by finasteride (1.0 mg/kg) and smaller than that by allylestrenol (10 mg/kg) or CMA (10 mg/kg). However, allylestrenol increased liver weights, and CMA increased liver and reduced adrenal weights. These results demonstrate that FK143 can decrease the volume of the dog prostate without any influence on other organs, and they suggest that FK143 is a good candidate for the treatment for benign prostatic hyperplasia. (+info)Effects of steroid 5alpha-reductase inhibitor ONO-9302 and anti-androgen allylestrenol on the prostatic growth, and plasma and prostatic hormone levels in rats. (5/5)
ONO-9302 [epristeride; (-)-17beta-(tert-butylcarbamoyl)androsta-3,5-diene-3-carboxy lic acid] is a novel inhibitor of steroid 5alpha-reductase. We studied in vitro and in vivo effects of ONO-9302 on the rat prostatic tissue in comparison with those of the anti-androgen allylestrenol. ONO-9302 inhibited the rat prostatic enzyme with an IC50 value of 11 nM, whereas allylestrenol was about 80,000-fold less potent. The growth of ventral prostate, which was induced by the subcutaneous injection of testosterone propionate in the castrated rats, was significantly reduced by ONO-9302 at oral doses of 1-100 mg/kg/day. Allylestrenol showed a significant effect only at a dose of 100 mg/kg/day. In mature male rats, ONO-9302 significantly reduced the ventral prostate weight at doses of 10-100 mg/kg/day and decreased prostatic 5alpha-dihydrotestosterone (DHT) content associated with a rise in testosterone (T) content at doses of 0.1-100 mg/kg/day. Plasma hormone levels (i.e., T, DHT, luteinizing hormone (LH) and follicle stimulating hormone (FSH)) were not altered significantly. Allylestrenol significantly reduced the ventral prostate weight at doses of 10-100 mg/kg/day. However, unlike ONO-9302, allylestrenol reduced both the prostatic DHT and T contents and also lowered plasma T, DHT, LH and FSH levels at a dose of 30 mg/kg/day. These results suggest that ONO-9302 reduces the prostatic growth by inhibiting the conversion of T to DHT in the prostate without lowering blood T level unlike anti-androgen drugs. (+info)
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- Allylestrenol is one of only a handful of progestogens that has commonly been used for such purposes, the others including progesterone, hydroxyprogesterone caproate, and dydrogesterone. (wikipedia.org)
- Allylestrenol is a progestogen, or an agonist of the progesterone receptor (PR). (wikipedia.org)
- Allylestrenol has less than 0.2% of the affinity of ORG-2058 and less than 2% of the affinity of progesterone for the PR. (wikipedia.org)
- Allylestrenol is a progestogen structurally related to progesterone that has been given in threatened and recurrent miscarriage, and to prevent premature labour. (salvavidaspharmaceutical.com)
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- Sep 24, 2017 - Allylestrenol is a synthetic progestogen used to treat miscarriages and preterm labor in women. (list-direct.com)
20183
- Allylestrenol (CAS 432-60-0) Market Research Report 2018 aims at providing comprehensive data on allylestrenol market globally and regionally (Europe, Asia, North America, Latin America etc. (marketpublishers.com)
- Allylestrenol (CAS 432-60-0) Market Research Report 2018 contents were worked out and placed on the website in November, 2018. (marketpublishers.com)
- Please note that Allylestrenol (CAS 432-60-0) Market Research Report 2018 is a half ready publication and contents are subject to change. (marketpublishers.com)
C21H32O1
- allylestrenol Product Name:Allylestrenol CAS:432-60-0 MF:C21H32O. (kitairu.net)
Gestin2
- Gestin (Allylestrenol) digunakan untuk membantu mencegah keguguran dan keguguran berulang, dan mungkin juga digunakan untuk membantu mencegah persalinan prematur. (biosteroids.com)
- Selalu gunakan Gestin (Allylestrenol) seperti yang telah diresepkan oleh dokter Anda. (biosteroids.com)
Tablet1
- In Japan, a 25 mg allylestrenol oral tablet, under the brand name Perselin, is marketed for the treatment of BPH. (wikipedia.org)
Dosage2
- The effective ovulation-inhibiting or contraceptive dosage of allylestrenol in women has been studied, albeit limitedly. (wikipedia.org)
- The total endometrial transformation dosage of allylestrenol in women across the cycle is 150 to 250 mg. (wikipedia.org)
Doses1
- At high doses, allylestrenol effectively stops premature labor, suggesting a selective action on the myometrium. (eoextract.com)
Gram1
- AASraw is with synthesis and production ability from gram to mass order of Allylestrenol powder (432-60-0) , under CGMP regulation and trackable quality control system. (aasraw.com)
Testosterone1
- Dimethisterone, also known as 6α,21-dimethylethisterone or as 6α,21-dimethyl-17α-ethynyltestosterone, as well as 17α-ethynyl-6α,21-dimethylandrost-4-en-17β-ol-3-one or as 6α,21-dimethyl-17β-hydroxy-17α-pregn-4-en-20-yn-3-one, is a synthetic androstane steroid and a derivative of testosterone . (readtiger.com)
Steroid2
- The binding and activity profiles of allylestrenol and its major active metabolite at steroid hormone receptors and related proteins have been studied. (wikipedia.org)
- Allylestrenol is a steroid. (list-direct.com)
Therapeutic1
- The therapeutic efficacy of Otamixaban can be decreased when used in combination with Allylestrenol. (drugbank.ca)
Oral1
- Allylestrenol adalah turunan progesteron oral efektif dengan aksi β-adrenergik selektif. (biosteroids.com)
Products1
- http://yuanchengh-b9.en.frbiz.com/images/ images - View more photos about - View images and photos from Yuancheng Technology Development Co., Ltd's products images list. (25healthyways.com)
Hormone1
- Unlike other progestins, allylestrenol has not been used in hormonal contraception or in menopausal hormone therapy. (wikipedia.org)
Sildenafil1
- We measured plasma levels of sildenafil, another less strong cysticidal drug business when allylestrenol was given simultaneously. (sbolot.org)
Pregnancy1
- Allylestrenol does not maintain pregnancy if placental dysfunction is present, however. (eoextract.com)
Side effects3
- Side effects of allylestrenol are few and have not been well-defined, but are assumed to be similar to those of related medications. (wikipedia.org)
- Allylestrenol has no androgenic or other off-target hormonal side effects. (wikipedia.org)
- Read the side effects of Allylestrenol as described in the medical literature. (medindia.net)
Medical1
- Allylestrenol was first described in 1958 and was introduced for medical use by 1961. (wikipedia.org)
Moisture1
- Allylestrenol powder is best stored at room temperature away from direct light and moisture. (aasraw.com)
Names1
- It captures allylestrenol market trends, pays close attention to allylestrenol manufacturers and names suppliers. (marketpublishers.com)
Women2
- On the other hand, allylestrenol was found to be effective in the treatment of hot flashes in postmenopausal women. (wikipedia.org)
- Allylestrenol was used to treat 375 women with threatened pregnancies. (list-direct.com)
Treatment5
- Allylestrenol is used in the treatment of recurrent and threatened miscarriage and to prevent premature labor. (wikipedia.org)
- Allylestrenol has also been studied in the treatment of prostate cancer in Japan. (wikipedia.org)
- When used at high dosages in the treatment of BPH in men, allylestrenol can cause symptoms of hypogonadism and sexual dysfunction. (wikipedia.org)
- Feb 18, 2020 - Allylestrenol is used in the treatment of Premature Labor,Recurrent miscarriage. (list-direct.com)
- Allylestrenol has also been studied as a treatment for benign prostatic hyperplasia in men, with encouraging results. (list-direct.com)
Drug1
- To prevent drug damage, you should not store Allylestrenol powder in the bathroom or the freezer. (aasraw.com)
Quality1
- Q2:How can we guarantee you receive a good quality Allylestrenol? (eoextract.com)