Chemicals and Drugs
AllylamineAminesNaphthalenesSqualene MonooxygenaseKetoconazoleIndolequinonesPolyamines
Allylamine
Possesses an unusual and selective cytotoxicity for VASCULAR SMOOTH MUSCLE cells in dogs and rats. Useful for experiments dealing with arterial injury, myocardial fibrosis or cardiac decompensation.
Amines
A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Naphthalenes
Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.
Squalene Monooxygenase
The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.
Ketoconazole
Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
Indolequinones
INDOLES which have two keto groups forming QUINONES like structures of the indole aromatic ring.
Polyamines

Systematic review of topical treatments for fungal infections of the skin and nails of the feet. (1/66)

OBJECTIVE: To identify and synthesise the evidence for efficacy and cost effectiveness of topical treatments for superficial fungal infections of the skin and nails of the feet. DESIGN: Systematic review. INTERVENTIONS: Topical treatments for superficial fungal infections. MAIN OUTCOME MEASURES: Cure confirmed by culture and microscopy for skin and by culture for nails in patients with clinically diagnosed fungal infections. RESULTS: Of 126 trials identified in 121 papers, 72 (57.1%) met the inclusion criteria. Placebo controlled trials yielded pooled relative risks of failure to cure skin infections: allylamines (0.30, 95% confidence interval 0.24 to 0.38); azoles (0.54, 0.42 to 0.68); undecenoic acid (0.28, 0. 11 to 0.74); and tolnaftate (0.46, 0.17 to 1.22). Although meta-analysis of 11 trials comparing allylamines and azoles showed a relative risk of failure to cure of 0.88 (0.78 to 0.99) in favour of allylamines, there was evidence of language bias. Seven reports in English favoured allylamines (0.79, 0.69 to 0.91), but four reports in foreign languages showed no difference between the two drugs (1. 01, 0.90 to 1.13). Neither trial of nail infections showed significant differences between alternative topical treatments. CONCLUSIONS: Allylamines, azoles, and undecenoic acid were efficacious in placebo controlled trials. There are sufficient comparative trials to judge relative efficacy only between allylamines and azoles. Allylamines cure slightly more infections than azoles but are much more expensive than azoles. The most cost effective strategy is first to treat with azoles or undecenoic acid and to use allylamines only if that fails.  (+info)

Opposite effects of GABA(A) and GABA(C) receptor antagonists on the b-wave of ERG recorded from the isolated rat retina. (2/66)

The largest component in the fully dark-adapted ERG is a corneal-positive response, known as the b-wave, and believed to originate from depolarizing (ON-type) bipolar cells. The two types of GABA receptors, GABA(A) and GABA(C) have been reported to exist on bipolar cells in rat retina. The goal of these experiments was to find whether these GABA receptors participate in the generation of the b-wave of electroretinogram (ERG). ERGs were recorded from the isolated rat retinas. The P(2)(t) component, obtained by subtracting the ERGs measured before the application of 50 micrograms APB from those measured after the application of 50 micrograms APB, was used as an indicator of depolarizing bipolar cell activity. Photovoltages, the fast P(3)(t) component of ERG, were registered between the two microelectrodes across the rod outer segments. Bicuculline and 3-aminopropylphosphonic acid (3-APA) were used as selective antagonists of GABA(A) and GABA(C) receptors, respectively. It was found that the GABA(A) and GABA(C) receptors antagonists have opposite effects on the b-wave: bicuculline increased the b-wave amplitude, while 3-APA reduced the amplitude of the b-wave. Neither bicuculline nor 3-APA affect photoreceptors.  (+info)

New therapies on the horizon. (3/66)

Statins have proved to be potent drugs for reducing low-density lipoprotein cholesterol (LDL-C) levels. However, because the response to current statin therapy regimens is not always sufficient to reach defined goal levels, additional drugs to lower LDL-C are needed. New drugs may soon be available to lower LDL-C levels by mechanisms that differ from those of the statins. Among these new agents are a bile acid binding resin, inhibitors of bile acid transport, inhibitors of cholesterol transport, inhibitors of cholesterol esterification, and triglyceride-lowering agents.  (+info)

The development of an in-vitro perfusion system for studies on cultured cells. (4/66)

The design and use of a perfusion system, using a modified flow chamber for studies on cultured animal cells, is described. Rat thoracic aorta smooth muscle cells were isolated by an explant method and grown on Thermanox coverslips. These were introduced into the flow chamber. A flow rate of 25ml/min and a shear stress of 14.6 dynes/cm2 (12 dyne = 10 microN) (both within physiological limits) were maintained. Cells remained attached to the coverslips after 8h of perfusion with culture medium. The effect of exposing rat smooth muscle cells to the cardiovascular toxin, allylamine, is also described. The components of the system are routinely available, simple to clean, easy to assemble and sterilize. The incorporation of an in-line sensor that monitors pH, PO2, PCO2 and temperature ensures that the perfusion conditions remain within physiological limits. Automation means that minimal supervision is required. This system provides a potential mechanism in which cultured vascular cells may be perfused under controlled haemodynamic conditions, and their response to a cytotoxin may be evaluated.  (+info)

Overview of pharmacologic therapy for the treatment of dyslipidemia. (5/66)

Although the National Cholesterol Education Program Adult Treatment Panel III (ATP III) guidelines stress the importance of nonpharmacologic lipid modification interventions such as diet and exercise, the guidelines also recognize that many patients will require drug therapy to achieve low-density lipoprotein cholesterol (LDL-C) target goals. Currently available lipid-modifying drugs include bile acid sequestrants (or resins), fibrates, nicotinic acid, and statins, with each class exerting different effects on the lipid profile. In addition, nonprescription agents such as plant stanols and sterols have been shown to be effective in modifying plasma lipids. Of these agents, the statins are the most effective, most widely prescribed, and best-tolerated form of lipid-lowering drug therapy. New formulations of other drugs, such as niacin and bile acid sequestrants, can also improve treatment regimes and reduce side effects, thereby improving patient compliance with these therapies. In patients who have high levels of LDL-C and triglycerides together with low concentrations of high-density lipoprotein cholesterol (HDL-C), combination therapy may be required. Ezetimibe, a selective cholesterol absorption inhibitor, is the first of a new class of lipid-lowering agents and provides a new agent for the management of patients with dyslipidemia. Data from the ezetimibe clinical development program suggests that this agent can be used alone or in combination with statins to reduce LDL-C, improve compliance, and bring more patients to ATP III target goal.  (+info)

Regulation of alpha7-integrin expression in vascular smooth muscle by injury-induced atherosclerosis. (6/66)

Injury of vascular smooth muscle cells (VSMCs) by allylamine (AAM) leads to phenotypic changes associated with atherogenic progression including increased proliferation, migration, and alterations in cell adhesion. In the present study, the relationship between AAM-induced vascular injury and expression of the alpha(7)-integrin subunit was investigated. The alpha(7)-mRNA and protein expression were examined using real-time RT-PCR, fluorescence-activated cell sorting analysis (FACS), immunohistochemistry, and immunoblotting. In cultured VSMCs from aortas of AAM-treated rats (70 mg/kg for 20 days), alpha(7)-mRNA levels were increased more than twofold compared with control cells. No change was seen in beta(1)-integrin expression. FACS analysis revealed increased cell surface expression of alpha(7)-protein (25 +/- 9%; *P < 0.05). AAM treatment of naive VSMCs enhanced alpha(7)-mRNA expression (2.4 +/- 0.7-fold, mean +/- SE; *P < 0.05). The increased alpha(7)-mRNA expression was attenuated by the amine oxidase inhibitor semicarbazide and the antioxidant pyrrolidine dithiocarbamate, which confirms a role for oxidative stress in modulating alpha(7)-expression. In vivo alpha(7)-mRNA and protein expression were enhanced in the aortas of AAM-treated rats. In addition, increased alpha(7)-integrin expression facilitated AAM VSMC adhesion to laminin more efficiently compared with control (51 +/- 2%; *P < 0.05). Chemical injury induced by AAM significantly enhances alpha(7)-integrin expression in VSMCs. These findings implicate for the first time the expression of alpha(7)-integrin during the response of VSMCs to vascular injury.  (+info)

Ketogenic diet decreases circulating concentrations of neuroactive steroids of female rats. (7/66)

Ketogenic diet (KD) is used to manage intractable epilepsy; however, the mechanisms underlying its therapeutic effects are not known. Steroid hormones, such as progesterone and testosterone, are derived from cholesterol, and are readily 5alpha-reduced to dihydroprogesterone and dihydrotestosterone, which are subsequently converted to 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) and 3alpha-androstanediol, neuroactive steroids that can influence seizures. The present study examined the effects of the KD on circulating concentrations of these neuroactive steroids, and their precursors, in intact female rats. Thirty-six, 22-day-old female Sprague-Dawley rats (weaned at 21 days) were fasted for 8 hours prior to placement on one of three dietary regimens for 6 weeks: ad libitum chow, calorie-restricted chow, or KD. After 6 weeks of the diet, when six rats in each dietary condition were in diestrus and six were in behavioral estrus, all rats were administered pentylenetetrazole (PTZ, 70 mg/kg, i.p.). The latency and incidence of seizures were recorded by an observer who was uninformed of the estrous cycle and dietary treatment conditions of the rats. Immediately after each test, trunk blood was obtained for later measurement of pregnane (progesterone, dihydroprogesterone, 3alpha,5alpha-THP) and androstane (testosterone, dihydrotestosterone, 3alpha-androstanediol) neuroactive steroid concentrations in plasma by radioimmunoassay. KD tended to lengthen the latency to, and significantly reduced the number of, PTZ-induced barrel roll seizures. KD also significantly reduced plasma levels of the pregnane (dihydroprogesterone, 3alpha,5alpha-THP) and androstane (dihydrotestosterone, 3alpha-androstanediol) 5alpha-reduced metabolites. These data suggest that levels of pregnane and androstane neuroactive steroids, or their precursors, may underlie some of the antiseizure effects of KD.  (+info)

Asymmetric synthesis of 4,5,6- and 3,4,5,6-substituted azepanes by a highly diastereoselective and enantioselective lithiation-conjugate addition sequence. (8/66)

Asymmetric syntheses of 4,5,6- and 3,4,5,6-substituted azepanes have been achieved by highly diastereoselective and enantioselective (-)-sparteine-mediated asymmetric lithiation-conjugate additions of N-Boc-N-(p-methoxyphenyl)-2,3-substituted allylamines to a beta-aryl alpha,beta-unsaturated ester followed by hydrolysis, cyclization, and reduction. Access to the enantiomeric adduct is provided by an invertive lithiation-stannylation-lithiation sequence.  (+info)

Bile acid sequestrant - WikipediaBile acid sequestrant - Wikipedia
The bile acid sequestrants are a group of resins used to bind certain components of bile in the gastrointestinal tract. They disrupt the enterohepatic circulation of bile acids by combining with bile constituents and preventing their reabsorption from the gut. In general, they are classified as hypolipidemic agents, although they may be used for purposes other than lowering cholesterol. They are used in the treatment of chronic diarrhea due to bile acid malabsorption. Bile acid sequestrants are polymeric compounds that serve as ion-exchange resins. Bile acid sequestrants exchange anions such as chloride ions for bile acids. By doing so, they bind bile acids and sequester them from the enterohepatic circulation. The liver then produces more bile acids to replace those that have been lost. Because the body uses cholesterol to make bile acids, this reduces the amount of LDL cholesterol circulating in the blood. Bile acid sequestrants are large polymeric structures, and they are not significantly ...
https://en.wikipedia.org/wiki/Bile_acid_sequestrant
Long-term (52-78 weeks) treatment with colesevelam HCl added to | DMSOLong-term (52-78 weeks) treatment with colesevelam HCl added to | DMSO
Long-term (52â 78 weeks) treatment with colesevelam HCl added to metformin therapy in type 2 diabetes mellitus patients Harold E BaysLouisville Metabolic and Atherosclerosis Research Center, Louisville, Kentucky, USAObjective: To evaluate the long-term safety, tolerability, and efficacy of colesevelam HCl (colesevelam) in type 2 diabetes mellitus patients receiving metformin monotherapy or metformin combination therapy.Methods: This post-hoc subgroup analysis examined data from type 2 diabetes mellitus patients aged 18 to 75 years with a hemoglobin A1c of 7.5% to 9.5%, who received metformin as part of their treatment via their participation in one of three randomized, double-blind base studies wherein colesevelam (3.75 g/day) or a placebo was added to existing metformin-, insulin-, or sulfonylurea-based treatment. After completing the base studies, the subjects who initially received blinded colesevelam (n = 196) or the placebo (n = 166) entered a 52-week extension study wherein they received open
https://www.dovepress.com/long-term-52ndash78-weeks-treatment-with-colesevelam-hcl-added-to-metf-peer-reviewed-article-DMSO
Allylamine and β-aminopropionitrile induced aortic medial necrosis: Mechanisms of synergism<...Allylamine and β-aminopropionitrile induced aortic medial necrosis: Mechanisms of synergism<...
TY - JOUR. T1 - Allylamine and β-aminopropionitrile induced aortic medial necrosis. T2 - Mechanisms of synergism. AU - Kumar, D.. AU - Trent, M. B.. AU - Boor, P. J.. PY - 1998/2/6. Y1 - 1998/2/6. N2 - We have developed a model of aortic smooth muscle necrosis in adult Sprague Dawley rats by feeding them two vascular toxins (allylamine HCl, or AA, and β-aminopropionitrile, or βAPN) in concert for 10 days. Either toxin given alone does not cause aortic lesions. In order to shed light on the mechanism of the synergistic action of these two toxins we fed known modulators of AA or βAPN toxicity to rats concurrently with the two toxins. As modulators we used (a) semicarbazide (98 mg/kg/day, given 4 h prior to toxins), a known inhibitor of the vascular enzyme SSAO which metabolizes AA (b) L-cysteine (1.5% in rat chow, beginning 3 days prior to toxins), which has been shown to reduce the toxic effects of βAPN; and (c) phenelzine sulphate (3 mg/kg/day, given 4 h prior to toxins), an inhibitor of ...
https://researchexperts.utmb.edu/en/publications/allylamine-and-%CE%B2-aminopropionitrile-induced-aortic-medial-necrosi
Systems for Removing Dimethyl Sulfoxide (Dmso) or Related Compounds or Odors Associated with Same - Patent applicationSystems for Removing Dimethyl Sulfoxide (Dmso) or Related Compounds or Odors Associated with Same - Patent application
0086]In one embodiment, the odor adsorbing fibers of the fabric may comprise a modified polyamine which comprises a hybrid inorganic/organic material comprising a polyamine and an inorganic oxide. The polyamine may comprise one or more of the following: amine-containing polysaccharides, amine-containing polypeptides, polyethylenimine, polyethylenimine derivatives, poly(vinylamine), poly(diallylamine), poly(allylamine), copolymers of diallylamine and allylamine, copolymers containing diallylamine or allylamine, copolymers containing diallylamine and allylamine, and condensation polymers formed from polyamine monomers and monomers with two or more amine-reactive groups, poly(lysine), polyethylenimine, polyethylenimine derivatives, poly(vinylamine), polymers containing diallylamine, and polymers containing allylamine, amine-containing polysaccharides, amine-containing polypeptides, polyethylenimine, polyethylenimine derivatives, poly(vinylamine), poly(diallylamine), poly(allylamine), copolymers of ...
http://www.patentsencyclopedia.com/app/20080251081
Allylamine - Registration Dossier - ECHAAllylamine - Registration Dossier - ECHA
The systemic toxic potential of Allylamine was assessed when administered to Sprague Dawley rats by snout-only inhalation administration for 4 weeks. Recovery from any effects was evaluated during a 2 week recovery period. Three groups, each comprising 5 male and 5 female Sprague Dawley rats, received Allylamine at target exposures of 5, 10 or 20 ppm. A similarly constituted control group received air only, at the same operating conditions as the high dose group. A further five male and five female rats were assigned to each of the control and high dose groups. These animals were treated for 4 weeks, followed by a 2 week period without treatment to assess the potential for any treatment-related change to recover. During the study, clinical condition, detailed physical and arena observations, sensory reactivity, grip strength, motor activity, bodyweight, food consumption, haematology (peripheral blood), haematology (bone marrow), blood chemistry, organ weights, macropathology and histopathology ...
https://www.echa.europa.eu/web/guest/registration-dossier/-/registered-dossier/5470/7/6/1
Bile Acid Sequestrants and the Treatment of Type 2 Diabetes Mellitus | SpringerLinkBile Acid Sequestrants and the Treatment of Type 2 Diabetes Mellitus | SpringerLink
Bile acids promote bile formation and facilitate dietary lipid absorption. Animal and human studies showing disturbed bile acid metabolism in diabetes mellitus suggest a link between bile acids and glucose control. Bile acids are activating ligands of the farnesoid X receptor (FXR), a nuclear receptor with an established role in bile acid and lipid metabolism. Evidence suggests a role for FXR also in maintenance of glucose homeostasis. Animal and human studies employing bile acid sequestrants (bile acid binding agents), which interrupt the enterohepatic circulation of bile acids and effectively reduce plasma cholesterol, support a link between bile acid and glucose metabolism. In lipid-lowering trials, bile acid sequestrants, such as colesevelam hydrochloride, colestyramine (cholestyramine) and colestilan (colestimide), have also been shown to lower plasma glucose and glycosylated haemoglobin levels, suggesting the utility of these agents as a potential therapy for type 2 diabetes. In this ...
https://link.springer.com/article/10.2165%2F00003495-200767100-00001
Bile Acid Sequestrant Drugs | Grand Strand HealthBile Acid Sequestrant Drugs | Grand Strand Health
Learn more about Bile Acid Sequestrant Drugs at Grand Strand Medical Center Many Nutrients - Supplementation Likely Helpful The bile acid sequestrant...
https://grandstrandmed.com/hl/?/21493/Bile-Acid-Sequestrant-Drugs&com.dotmarketing.htmlpage.language=1
polypyrrole coated iron oxide nanoparticles modified with poly(allylamine hydrochloride)polypyrrole coated iron oxide nanoparticles modified with poly(allylamine hydrochloride)
Page contains details about polypyrrole coated iron oxide nanoparticles modified with poly(allylamine hydrochloride) . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
http://nano.nature.com/nano/GR-M7942985
kinesin-NH2-NTA-modified sodium alginate/fluorescein isothiocyanate-modified poly(allylamine hydrochloride)/dextran sulfate...kinesin-NH2-NTA-modified sodium alginate/fluorescein isothiocyanate-modified poly(allylamine hydrochloride)/dextran sulfate...
Page contains details about kinesin-NH2-NTA-modified sodium alginate/fluorescein isothiocyanate-modified poly(allylamine hydrochloride)/dextran sulfate sodium multilayer tubes . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
http://nano.nature.com/nano/GR-M6210900
Centre de biophysique moléculaire - UPR 4301 - Gene delivery efficiency and intracellular trafficking of novel poly(allylamine)...Centre de biophysique moléculaire - UPR 4301 - Gene delivery efficiency and intracellular trafficking of novel poly(allylamine)...
Abstract : Non-viral gene carriers for safe and efficient gene transfection have become of particular interest among researchers of different disciplines ranging from physical chemistry to biotechnology. Recently polymeric vectors have been extensively studied as potentially new gene transfer agents. Until now most of the research efforts were made to optimize the gene-to-polymer weight ratio of polyplexes for safe and efficient gene transfection. In this work, we report on the development of novel poly(allylamine) derivatives with different balance of the primary, secondary, tertiary, and quaternary amino groups. All derivatives were able to complex pDNA into polyplexes at low gene-to-polymer weight ratios i.e., 1:1 or 1:2. Moreover, the examined polyplexes were less cytotoxic and showed better transfection efficiency when compared to linear poly(ethyleneimine). These results indicate that the presence of quaternary ammonium groups is important in the formation of stable polyplexes. Polymers ...
http://cbm.cnrs-orleans.fr/spip.php?article6788
Welchol (Colesevelam Hcl): Side Effects, Interactions, Warning, Dosage & UsesWelchol (Colesevelam Hcl): Side Effects, Interactions, Warning, Dosage & Uses
Learn about Welchol (Colesevelam Hcl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications.
https://www.rxlist.com/welchol-drug.htm
Colesevelam Hydrochloride (Professional Patient Advice) - Drugs.comColesevelam Hydrochloride (Professional Patient Advice) - Drugs.com
Professional guide for Colesevelam Hydrochloride. Includes: pharmacology, pharmacokinetics, contraindications, interactions, adverse reactions and more.
https://www.drugs.com/ppa/colesevelam-hydrochloride.html
Which medications in the drug class Bile Acid Sequestrants are used in the treatment of Crohn Disease?Which medications in the drug class Bile Acid Sequestrants are used in the treatment of Crohn Disease?
Bile Acid SequestrantsPatients with terminal ileal disease may not absorb bile acids normally, which can lead to secretory diarrhea in the colon. These patients may benefit from bile acid sequestrants... more
https://www.medscape.com/answers/172940-18379/937574-overview
Bile acid sequestrants for cholesterolBile acid sequestrants for cholesterol
Davidson DJ, Wilkinson MJ, Davidson MH. Combination therapy for dyslipidemia. In: Ballantyne CM, ed. Clinical Lipidology: A Companion to Braunwalds Heart Disease. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 27.. Genest J, Libby P. Lipoprotein disorders and cardiovascular disease. In: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwalds Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Philadelphia, PA: Elsevier; 2019:chap 48.. Goldberg AC. Bile acid sequestrants. In: Ballantyne CM, ed. Clinical Lipidology: A Companion to Braunwalds Heart Disease. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 22.. Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2019;73(24):e285-e350. PMID: 30423393 ...
http://ccok.adam.com/content.aspx?productid=117&isarticlelink=false&pid=60&gid=000787
Molecules | Free Full-Text | Synthesis of Homoveratric Acid-Imprinted Polymers and Their Evaluation as Selective Separation...Molecules | Free Full-Text | Synthesis of Homoveratric Acid-Imprinted Polymers and Their Evaluation as Selective Separation...
A bulk polymerization method was used to easily and efficiently prepare homo-veratric acid (3,4-dimethoxyphenylacetic acid)-imprinted polymers from eight basic monomers: 2-vinylpyridine, 4-vinylpyridine, 1-vinylimidazole, N-allylaniline, N-allylpiperazine, allylurea, allylthiourea, and allylamine, in the presence of homoveratric acid as a template in N,N-dimethylformamide as a porogen. The imprinted polymer prepared from allylamine had the highest affinity to the template, showing an imprinting factor of 3.43, and allylamine polymers MIP8/NIP8 were selected for further studies. Their binding properties were analyzed using the Scatchard method. The results showed that the imprinted polymers have two classes of heterogeneous binding sites characterized by two pairs of Kd, Bmax values: Kd(1) = 0.060 μmol/mL, Bmax(1) = 0.093 μmol/mg for the higher affinity binding sites, and Kd(2) = 0.455 μmol/mL, Bmax(2) = 0.248 μmol/mg for the lower affinity binding sites. Non-imprinted polymer has only one class of
http://www.mdpi.com/1420-3049/16/5/3826
Naftifine - WikipediaNaftifine - Wikipedia
Naftifine (brand name Exoderil) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis (fungal infections). Naftifine has triple action: antifungal, antibacterial and anti-inflammatory. Its precise mechanism of action is unknown, but may involve selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme. The half-life is approximately 2-3 days. The metabolites are excreted in the urine and feces. Robertson Dirk B, Maibach Howard I, Chapter 61. Dermatologic Pharmacology (Chapter). Bertram G. Katzung, Susan B. Masters, Anthony J. Trevor: Basic & Clinical Pharmacology, 11e: http://www.accesspharmacy.com/content.aspx?aID=4517257. Micromedex DRUGDEX Drug Point: Naftifine Hydrochloride. Accessed at www.thomsonhc.com/../BeginWith#secN10184, February 18, 2010. AccessPharmacy: Drug Monographs: Naftifine. Accessed at http://www.accesspharmacy.com/drugContentPopup.aspx?mid=6620§ion=10, February 18, 2010 ...
https://en.wikipedia.org/wiki/Naftifine
Allylamine - Registration Dossier - ECHAAllylamine - Registration Dossier - ECHA
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
https://chesar.echa.europa.eu/web/guest/registration-dossier/-/registered-dossier/5470/7/3/1
Effects on Colesevelam HC1 (WelChol®) on Insulin Sensitivity in Subjects With Type 2 Diabetes Mellitus - Full Text View -...Effects on Colesevelam HC1 (WelChol®) on Insulin Sensitivity in Subjects With Type 2 Diabetes Mellitus - Full Text View -...
Single-center, randomized, parallel, double-blind, placebo controlled, 8-week trial in subjects with type 2 diabetes mellitus. Two parallel treatment groups include double-blind colesevelam or placebo. A screening period may be up to 18 weeks to withdraw non sulfonylurea antidiabetic treatment or withdraw or adjust sulfonylurea antidiabetic treatment. To evaluate hepatic and peripheral insulin sensitivity, subjects will undergo a two-step hyperinsulinemic-euglycemic clamp with a tritiated glucose infusion at pre randomization and after 8 weeks of treatment. To evaluate oral glucose absorption, subjects will undergo two oral glucose tolerance tests (OGTT) at pre randomization, one without colesevelam and one with colesevelam, and one OGTT at the end of the treatment period ...
https://clinicaltrials.gov/ct2/show/NCT00361153
Colesevelam - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWikiColesevelam - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
Colesevelam - Get up-to-date information on Colesevelam side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Colesevelam
https://rxwiki.com/colesevelam
Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose...Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose...
The only disclosure restriction on the PI is that the sponsor can review results communications prior to public release and can embargo communications regarding trial results for a period that is more than 60 days but less than or equal to 180 days. The sponsor cannot require changes to the communication and cannot extend the embargo ...
https://clinicaltrials.gov/ct2/show/results/NCT00484419
RxHealthMedRxHealthMed
Constipation: Colesevelam may cause or worsen constipation. Fecal impaction (a large mass of stool that may be lodged in the colon) and worsening of hemorrhoids may occur. Talk to your doctor as soon as possible if any of these side effects become bothersome.. Drug interactions: Colesevelam can interact with other medications, such as birth control pills, cyclosporine, and warfarin (see What medications can interact with colesevelam? for more medications). If you take any of these medications, you should wait at least 4 hours before taking colesevelam. Your doctor will monitor you and the other medications you are taking while you are taking colesevelam. In general, if a drug interaction cannot be ruled out, you should take colesevelam at least 4 hours after your other medications in order to lessen the risk of the other medications not being fully absorbed into the body. Gastrointestinal: The safety and efficacy of colesevelam have not been established for people with swallowing problems, ...
http://www.rxhealthmed.ca/health-advice/medication-search/med/6081
Terbinafine - American Osteopathic College of Dermatology (AOCD)
Terbinafine is an allylamine antifungal medication. The medication can be administered orally or topically as a cream. The topical treatment was officially approved by the FDA in 1993 and can be bought over the counter. The oral treatment was approved in 1996 and widely distributes in the central nervous system, hair and nail beds and may remain there for up to three months because of extended elimination from skin and adipose tissue. Terbinafine is metabolized in the liver and 70% is excreted in the urine.. Mechanism: Terbinafine has a fungicidal effect by inhibiting the enzyme squalene monooxygenase which is involved in the synthesis of sterol in fungi. This inhibits fungal sterol biosynthesis by decreasing ergosterol levels. Fungal membranes are not able to grow because ergosterol is one of the main components of the fungal cell membrane. Additionally, squalene accumulates which weakens the cell membrane. Orally, the drug is very effective due to its ability to concentrate within the ...
http://www.aocd.org/?page=Terbinafine
Simvastatin vs Atorvastatin vs Lipitor vs Colesevelam Comparison - Drugs.comSimvastatin vs Atorvastatin vs Lipitor vs Colesevelam Comparison - Drugs.com
Compare Simvastatin vs Atorvastatin vs Lipitor vs Colesevelam head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Simvastatin rated 5.1/10 vs Atorvastatin rated 4.4/10 vs Lipitor rated 4.7/10 vs Colesevelam rated 8.3/10 in overall patient satisfaction.
https://www.drugs.com/compare/simvastatin-vs-atorvastatin-vs-lipitor-vs-colesevelam
Colesevelam - where does it fit into our clinical practice? - The British Journal of CardiologyColesevelam - where does it fit into our clinical practice? - The British Journal of Cardiology
Introduction Bile acid sequestrants (BAS) were the first class of lipid-lowering drug to be developed for reducing blood cholesterol levels.1 Now, after their introduction 30 years ago, BAS still continue to command a position in the treatment of hyperlipidaemia.2 How do BAS work? BAS bind to negatively charged b ...
https://bjcardio.co.uk/2009/11/colesevelam-where-does-it-fit-into-our-clinical-practice/
Pancreatitis | The Crohnoid Blog - Living with Crohns DiseasePancreatitis | The Crohnoid Blog - Living with Crohns Disease
Monday - 13th March 2017 - off to see my GP to get a prescription for Colesevelam, a bile acid sequestrant. He greeted me with bloody hell, you look well! I didnt understand the reason for his comment until later. We agreed on the new drug and he also reviewed my existing medications. So far so good.. He had been reading my medical record, the last entry of which was a trip to A&E with jaundice. He had assumed that I was back to see him with a recurrence of the problem, hence his comment. He asked me what the plan was following discharge back at the beginning of February. As far as I was concerned I had undergone a follow-up ultrasound scan and it was now matter closed. Clearly he thought there should have been some follow-up. He was rather miffed that I had heard nothing and said that he would chase it up.. We then had a fairly lengthy discussion on gallstones and surgery to have my gallbladder removed. That was a bit of a shock. I had gone in to get a prescription and come away with a ...
http://www.wrestlingtheoctopus.com/category/pancreatitis/
Terbinafine inhibits endothelial cell migration through suppression of the Rho-mediated pathway<...
TY - JOUR. T1 - Terbinafine inhibits endothelial cell migration through suppression of the Rho-mediated pathway. AU - Ho, Pei Yin. AU - Zhong, Wen-Bin. AU - Ho, Yan Soon. AU - Lee, Wen Sen. PY - 2006/12. Y1 - 2006/12. N2 - We showed previously that terbinafine, an allylamine with fungicidal activity, could inhibit angiogenesis by suppressing the endothelial cell proliferation. In the present study, we further showed that terbinafine (0-120 μmol/L) dose dependently inhibited the adhesion and migration of human umbilical vascular endothelial cells (HUVEC). Western blot analysis showed that terbinafine decreased the levels of Ras protein and membrane-bound RhoA protein. Moreover, the terbinafine-induced migration inhibition in HUVEC was prevented by pretreatment with farnesol or geranylgeraniol. Pretreatment of HUVEC with Ras inhibitor peptide or a ROCK (a kinase associated with RhoA for transducing RhoA signaling) inhibitor, Y27632, abolished the farnesol- or geranylgeraniol-induced prevention ...
https://tmu.pure.elsevier.com/en/publications/terbinafine-inhibits-endothelial-cell-migration-through-suppressi
Could it be fungal? | Sinclair DermatologyCould it be fungal? | Sinclair Dermatology
It is also important to look for any other co-existing infection that might need to be treated at the same time, such as secondary bacterial infection of a fungal rash or a fungal infection occurring elsewhere on the body.. Most fungal skin infections can be successfully treated with an appropriate topical antifungal such as, for example, an azole or allylamine.. Oral antifungal medication is generally only required if the infection is particularly extensive or severe, if it is resistant to topical antifungal therapy, or sometimes if it affects certain hair-bearing areas such as the scalp.. The choice of topical azole depends on both the characteristics of the rash and the likely pathogen, as well as the relative antibacterial and anti-inflammatory effects of the medication.. Click here to read more in the article published on Sep 2016 by Professor Rodney Sinclair.. ...
https://www.sinclairdermatology.com.au/could-it-be-fungal/
Electrokinetic Study of Bovine Serum Albumin Adsorption on Previously Formed PAH/PSS Multilayer - Faculty of Science Repository
Layer-by-layer structures (e.g. polyelectrolyte multilayers and protein-polyelectrolyte multilayers) play a very important role in surface modification processes. In the present study, electrokinetic measurements were applied for the investigation of poly(allylamine hydrochloride)/poly(sodium 4-styrenesulphonate) (PAH/PSS) multilayer formation, with PAH being a terminal layer, as a function of pH. Additionally, the effect of supporting electrolyte (KCl) concentration on multilayer formation was tested. Silica particles were used as the solid substrate. Furthermore, the adsorption of bovine serum albumin (BSA) on previously formed multilayer was examined as a function of pH and BSA concentration. It was confirmed that the electrokinetic measurements are suitable for monitoring the formation of various multilayers. In all investigated systems the process of multilayer formation was found to depend on conditions (ionic strength and pH) under which the multilayer was formed. Moreover, in the case of ...
http://digre.pmf.unizg.hr/1077/
Enhanced scratch resistance of self-assembled silica nanoparticle anti-reflection coatings - Journal of Materials Chemistry C ...Enhanced scratch resistance of self-assembled silica nanoparticle anti-reflection coatings - Journal of Materials Chemistry C ...
The layer-by-layer ionic self-assembly of silica nanoparticles (SiO2 NPs) and poly(allylamine hydrochloride) (PAH) can yield high-quality, tunable, and cost-effective anti-reflection coatings (ARCs). However, these purely ionic films lack the necessary scratch resistance for long-term stability. The addition of the
http://pubs.rsc.org/en/content/articlelanding/2018/tc/c7tc04457g
The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particlesThe support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles
Stroke causes extensive cellular loss that leads to a disintegration of the afflicted brain tissue. Although transplanted neural stein cells can recover some of the function lost after stroke, recovery is incomplete and restoration of lost tissue is minimal. The challenge therefore is to provide transplanted cells with matrix support in order to optimise their ability to engraft the damaged tissue. We here demonstrate that plasma polymerised allylamine (ppAAm)-treated poly(D,L-lactic acid-co-glycolic acid) (PLGA) scaffold particles can act as a structural support for neural stem cells injected directly through a needle into the lesion cavity using magnetic resonance imaging-derived co-ordinates. Upon implantation, the neuro-scaffolds integrate efficiently within host tissue forming a primitive neural tissue. These neuro-scaffolds could therefore be a more advanced method to enhance brain repair. This study provides a substantial step in the technology development required for the translation of ...
https://uhra.herts.ac.uk/handle/2299/12314
Brevet US4772484 - Biologically useful polymer preparations - Google BrevetsBrevet US4772484 - Biologically useful polymer preparations - Google Brevets
Described and claimed are biologically useful crosslinked copolymers of vinyl pyrrolidone and allylamine suitable for various preventative and therapeutic applications to intact or injured skin. Coatings of these copolymers, either preformed or prepared in situ on the skin may deliver medicaments to the skin, may serve as an iontophoretic medium, may provide electrical contact with the body, may regulate or control moisture loss from injured integument. Monolithic devices for the delivery of pharmaceutically active agents within living tissue may be formulated from these copolymers.
http://www.google.fr/patents/US4772484?hl=fr
Adult rat myocardial slices: A tool for studies of comparative cardiotoxicity<...
TY - JOUR. T1 - Adult rat myocardial slices. T2 - A tool for studies of comparative cardiotoxicity. AU - Parrish, A. R.. AU - Dorr, Robert T. AU - Gandolfi, A Jay. AU - Brendel, K.. PY - 1994. Y1 - 1994. N2 - The applicability of myocardial slices in comparative cardiotoxicity studies was investigated using the known cardiotoxicants allylamine (AAM) and doxorubicin (DOX). Precision-cut adult rat myocardial slices are a recently developed in vitro system. Previously, it has been demonstrated that myocardial slices are viable for up to 24 hr in organ culture. Myocardial slices exhibited a concentration- and time-dependent loss of viability in response to exposure to AAM or DOX (10-7, 10-6 or 10-5 m) during 24 hr in culture, as assessed by biochemical parameters including protein synthesis, ATP content, lipid peroxidation and the loss of the cytosolic enzyme creatine kinase. Protein synthesis and ATP content were sensitive indicators of slice viability, while lipid peroxidation was affected only by ...
https://arizona.pure.elsevier.com/en/publications/adult-rat-myocardial-slices-a-tool-for-studies-of-comparative-car
Descripción: SERS in PAH-Os and gold nanoparticle self-assembled multilayersDescripción: SERS in PAH-Os and gold nanoparticle self-assembled multilayers
We present a detailed structural and surface-enhanced Raman scattering (SERS) study of poly(allylamine) modified with Os (byp)2 ClPyCHO (PAH-Os) and gold nanoparticles self-assembled multilayers [PAH-Os+ (Au-nanoparticlesPAH-Os)n, n=1 and 5]. Atomic force microscopy and variable-angle spectroscopic ellipsometry measurements indicate that the first nanoparticle layer grows homogenously by partially covering the substrate without clustering. Analyzing the sample thickness and roughness we infer that the growth process advances thereafter by filling with nanoparticles the interstitial spaces between the previously adsorbed nanoparticles. After five immersion steps the multilayers reach a more compact structure. The interaction between plasmons of near-gold nanoparticles provides a new optical absorption around 650 nm which, in addition, allows a more effective SERS process in that spectral region than at the single-plasmon resonance (∼530 nm). We compare the electronic resonance Raman and SERS ...
http://www.lareferencia.info/vufind/Record/AR_8707bfb61d3656316571118216c844ca
Direct linkDirect link
A novel route to cyclic imines based on 5-exo radical cyclization is explored. The radical precursors are imines prepared from allylamine and readily available alpha-phenylselenenyl ketones.. ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2%3A296024
Plus itPlus it
RESULTS Fasting plasma glucose and HbA1c decreased with colesevelam (from 5.9 ± 0.1 to 5.7 ± 0.1 mmol/L, P , 0.05, and from 5.86 ± 0.06 to 5.76 ± 0.06%, P = 0.01, respectively), but fasting insulin did not change. Colesevelam had no effect on any FSIGT measures. In contrast, the MTT incremental area under the curve (iAUC) for both glucose (from 249.3 ± 28.5 to 198.8 ± 23.6 mmol/L ⋅ min, P , 0.01) and insulin (from 20,130 [13,542-35,292] to 13,086 [9,804-21,138] pmol/L ⋅ min, P , 0.05) decreased with colesevelam. However, the ratio of iAUC insulin to iAUC glucose was not changed. iAUC for cholecystokinin (CCK) increased (from 43.2 [0-130.1] to 127.1 [47.2-295.2] pmol/L ⋅ min, P , 0.01), while iAUC for fibroblast growth factor 19 decreased (from 11,185 [1,346-17,661] to 2,093 [673-6,707] pg/mL ⋅ min, P , 0.01) with colesevelam. However, iAUC for glucagon, glucose-dependent insulinotropic peptide, and glucagon-like peptide 1 did not change. ...
http://care.diabetesjournals.org/content/early/2012/03/26/dc11-2050
Colesevelam (Welchol) | Daviss Drug GuideColesevelam (Welchol) | Daviss Drug Guide
Find information on Colesevelam (Welchol) in Daviss Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.
https://im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/51171/all/colesevelam
WelChol (colesevelam) dosing, indications, interactions, adverse effects, and moreWelChol (colesevelam) dosing, indications, interactions, adverse effects, and more
Medscape - Indication-specific dosing for WelChol (colesevelam), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.
https://reference.medscape.com/drug/welchol-colesevelam-342449
Differences in SequestrantsDifferences in Sequestrants
In a final effort to get the yellow out of my water, I tried a third brand of sequestrant/chelating agent, Sequa-Sol It worked. The water is the best looking it has been to date. The previous two were Metal Free and Sea Klear Metal Klear. The MSDS on this new one says the active ingredient is Sodium Citrate. It is listed as a chelating agent where the previous two used Acrylamide-Acrylic Acid Copolymer, listed as a sequestrant. I cant find much that explains the difference, at least as
http://www.troublefreepool.com/threads/6923-Differences-in-Sequestrants
Lodalis Tablet - Uses, Side-effects, Reviews, and Precautions - Valeant Canada Lp Valeant Canada Sec - - Canada | all4insure.ru
Lodalis Tablet is used for high cholesterol levels, high cholesterol and other conditions. Lodalis Tablet contains the following active ingredients: Colesevelam Hydrochloride.
http://all4insure.ru/canada/lodalis-tablet
Cholesterol - All you need to Know!Cholesterol - All you need to Know!
Cholesterol-lowering drugs are known as antihyperlipidemic agents. There are five major groups: (1) Fibric acid derivatives - Atromid-S (clofibrate) and Lopid (gemdibrozil), which work by preventing the liver from making or releasing cholesterol into the bloodstream, (2) Bile acid sequestrants - Questran (cholestryamine) and Colestid (cholestipol), which bind to bile acids and prevent their absorption, (3) Nicotinic acid - Nicolar (nicotinic acid), which decreases the secretion of VLDL thus the formation of bad LDL cholesterol, (4) Probucol - Lorelco (probucol), which enhances the clearance of cholesterol including LDL and HDL cholesterol, and (5) HMG-CoA reductase inhibitors - Mevacor (lovastatin), Pravastatin, and Zocor (simvastatin), which work to help lower LDL cholesterol ...
http://nutractive-nutritionactivelifestyle.blogspot.com/2009/04/when-you-go-to-doctor-and-he-tells-you.html
Lipid-lowering agents for nephrotic syndrome | CochraneLipid-lowering agents for nephrotic syndrome | Cochrane
We included five RCTs enrolling a total of 203 participants. Of these, four studies compared statins with no treatment or placebo, and one compared fibrates with placebo. We found no published studies comparing second-line agents such as ezetimibe, bile acid sequestrants, and nicotinic acid with placebo or no treatment. Our assessment of the risk of bias found that one study was judged overall to be at low risk of bias and the remaining four were judged to be at high risk of bias.. Most outcomes were supported by single study data. One study reported significantly increased high density lipoprotein (HDL) cholesterol among participants in the statin arm compared with the no treatment group (MD 5.40 mg/dL, 95% CI 2.31 to 8.49). Another study reported higher serum albumin in the statin group compared to those who received no treatment (MD 0.60 g/dL, 95% CI 0.14 to 1.06). No serious adverse events, such as rhabdomyolysis, were reported, however some minor events occurred. One study reported no ...
https://www.cochrane.org/CD005425/RENAL_lipid-lowering-agents-for-nephrotic-syndrome
DMOZ - Health: Pharmacy: Drugs and Medications: Lipid-Lowering Agents
Drugs to reduce cholesterol and other lipids in blood. Classes of drugs used for this purpose include statins, bile acid sequestrants, nicotinic acid, and fibrates.
http://dmoztools.net/Health/Pharmacy/Drugs_and_Medications/Lipid-Lowering_Agents/
Primary biliary cirrhosis - Academic Kids
There is no known cure, but medication may slow the progression so that a normal lifespan and quality of life may be attainable. Ursodeoxycholic acid (Ursodiol) is one, which helps reduce the cholestasis. To relieve itching caused by bile acids in circulation, which would normally be removed by the liver, cholestyramine (a bile acid sequestrant) may be prescribed to absorb bile acids in the gut and be eliminated, rather than enter the blood stream. As in all liver diseases, alcoholic beverages are contraindicated. In advanced cases, a liver transplant, if successful, is said to have excellent prognosis. ...
https://academickids.com/encyclopedia/index.php/Primary_Biliary_Cirrhosis
Plus itPlus it
The strategy underlying the addition of a second or third agent is to optimize improvements in the lipid profile achieved by initial (usually statin) therapy. This strategy is based on the empirical assumption that further improvement in the lipid profile beyond that initially achieved will yield additional CVD benefit. However, there are as yet no controlled clinical trials comparing statin monotherapy with combination treatment.. It has been clearly shown that the addition of ezetimibe to a statin will lower LDL cholesterol to goal more often than statin monotherapy will.28 Bile acid sequestrants may also help to lower LDL cholesterol but should be used with caution because they have a triglyceride-raising effect in hypertriglyceridemic patients.29. It is also clear that achievement of all three lipid goals is more likely with statin plus fibrate or statin plus niacin combinations.30-32 However, the added complexity and risks of combination therapy in the absence of persuasive clinical trial ...
http://clinical.diabetesjournals.org/content/24/1/27
Alternatives to Advicor
There are several alternatives to Advicor, including other statins or cholesterol medicines. As this eMedTV page explains, besides statins, other cholesterol medicines include fibrates, cholesterol absorption inhibitors, and bile acid sequestrants.
http://cholesterol.emedtv.com/advicor/alternatives-to-advicor-p2.html
Vytorin Alternatives
Vytorin alternatives often include statins or other cholesterol medicines. This eMedTV article lists various types of statins and other classes of cholesterol medications, such as bile acid sequestrants, fibrates, and niacin.
http://cholesterol.emedtv.com/vytorin/vytorin-alternatives.html
South African Dyslipidaemia Guideline Consensus StatementSouth African Dyslipidaemia Guideline Consensus Statement
Bile acid sequestrants and nicotinic acid have cholesterollowering properties. They may occasionally be useful alone or in combination with statin therapy. However, their side-effects limit wider application.. 8.8 Treatment directed at other components of the lipid profile. Whereas low levels of HDL-C and high levels of TG are undoubtedly associated with a higher cardiovascular disease risk, no currently available treatment directed at reversing these changes has been shown to significantly benefit cardiovascular outcome.. A high triglyceride level, particularly if ,10 mmol/l, can result in acute pancreatitis and should be treated without delay.. 9. Special circumstances. 9.1 Metabolic syndrome. The European Guidelines recognise the importance of identifying patients with the metabolic syndrome, who are at increased risk of cardiovascular disease. The presence of the syndrome approximately doubles the risk of cardiovascular disease. Lifestyle changes, particularly reducing body weight and ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742012000300032&lng=en&nrm=iso&tlng=en
Allylamine - Medical Dictionary online-medical-dictionary.orgAllylamine - Medical Dictionary online-medical-dictionary.org
Possesses an unusual and selective cytotoxicity for Vascular Smooth Muscle Cells in Dogs and Rats. Useful for experiments dealing with arterial injury, myocardial Fibrosis or cardiac decompensation ...
http://www.online-medical-dictionary.org/definitions-a/allylamine.html
The synthesis of silicon and germanium quantum dots for biomedical applications | (2006) | Warner | Publications | SpieThe synthesis of silicon and germanium quantum dots for biomedical applications | (2006) | Warner | Publications | Spie
Silicon quantum dots have been synthesized in micelles. Particle sizes have been ascertained by transmission electron microscopy and UV-Vis absorption and photoluminescence spectroscopy. The surface of the silicon and germanium particles produced have been modified to produce hydrophobic and hydrophilic particles by reaction with either with 1-heptene or allylamine respectively. For biological applications control of the surface character of the nanocrystals is essential. FTIR spectra show the surface modification of the particles by 1-heptene or allylamine ...
http://spie.org/Publications/Proceedings/Paper/10.1117/12.647235
PatientsLikeMe | Colesevelam report for patients like youPatientsLikeMe | Colesevelam report for patients like you
Colesevelam: Find the most comprehensive real-world treatment information on Colesevelam at PatientsLikeMe. 5 patients with fibromyalgia, multiple sclerosis, major depressive disorder, generalized anxiety disorder, diabetes type 2, post-traumatic stress disorder, systemic lupus erythematosus, bipolar disorder, Parkinsons disease, panic disorder, rheumatoid arthritis, high blood pressure (hypertension), myalgic encephalomyelitis/chronic fatigue syndrome, persistent depressive disorder (dysthymia), amyotrophic lateral sclerosis, epilepsy, migraine, hypothyroidism, osteoarthritis, traumatic brain injury, attention deficit/hyperactivity disorder, bipolar II disorder, asthma, social anxiety disorder, high cholesterol (hypercholesterolemia), irritable bowel syndrome, idiopathic pulmonary fibrosis, gastroesophageal reflux disease, bipolar I disorder or psoriasis currently take Colesevelam.
https://www.patientslikeme.com/treatments/show/1993-colesevelam-side-effects-and-efficacy
Structure-Function Correlations of Two Highly Conserved Motifs in Saccharomyces cerevisiae Squalene Epoxidase▿ - COREStructure-Function Correlations of Two Highly Conserved Motifs in Saccharomyces cerevisiae Squalene Epoxidase▿ - CORE
Saccharomyces cerevisiae squalene epoxidase contains two highly conserved motifs, 1 and 2, of unknown function. Amino acid substitutions in both regions reduce enzyme activity and/or alter allylamine sensitivity. In the homology model, these motifs flank the flavin adenine dinucleotide cofactor and form part of the interface between cofactor and substrate binding domains ...
https://core.ac.uk/display/7972734
Nanoscale control of layer thickness for EL devices by mass-controlled layer-by-layer sequential adsorption process<...
TY - JOUR. T1 - Nanoscale control of layer thickness for EL devices by mass-controlled layer-by-layer sequential adsorption process. AU - Shiratori, Seimei. AU - Yamada, Masayoshi. AU - Ito, Takahiro. AU - Wang, Tom C.. AU - Rubner, Michael F.. PY - 2000/12/1. Y1 - 2000/12/1. N2 - A mass controlled layer-by-layer sequential adsorption process for polyelectrolytes was newly developed for the fabrication of functional devices using ultra-thin organic film formed by various polymers of different polarity of charge. In this study hydrophobic Ruthenium complex monomer (tris(bipyridyl) ruthenium(II) hexafluorophosphate) was micelle-wrapped with an anionic surfactant, sodium dodecylbenzenesulfonate, and was assembled with PAH (poly (allylamine hydrochloride)), which has the opposite charge, on ITO substrates. With this method, we succeeded in fabricating ultra-thin organic films even when the adsorption material is not polymer but monomer. Moreover it was found that the film thickness of the ...
https://keio.pure.elsevier.com/en/publications/nanoscale-control-of-layer-thickness-for-el-devices-by-mass-contr
Surface functionalization of nanoparticles to control cell interactions and drug release | Nanyang Technological University (DR...Surface functionalization of nanoparticles to control cell interactions and drug release | Nanyang Technological University (DR...
Nanoparticles made from poly(dl-lactide-co-glycolide) (PLGA) are used to deliver a wide range of bioactive molecules, due to their biocompatibility and biodegradability. This study investigates the surface modification of PLGA nanoparticles via the layer-by-layer (LbL) deposition of polyelectrolytes, and the effects of these coatings on the release behavior, cytotoxicity, hemolytic activity, and cellular uptake efficiency. PLGA nanoparticles are modified via LbL adsorption of two polyelectrolyte pairs: 1) poly(allylamine hydrochloride) (PAH) and poly(styrene sulfonate) (PSS) and 2) poly(L-lysine hydrobromide) (PLL) and dextran sulfate (DES). It is demonstrated that both PAH/PSS and PLL/DES coatings suppress the burst release usually observed for unmodified PLGA nanoparticles and that the release behavior can be adjusted by changing the layer numbers, layer materials, or by crosslinking the layer constituents. Neither bare nor polyelectrolyte-modified PLGA nanoparticles show any signs of ...
https://dr.ntu.edu.sg/handle/10356/96740?mode=full
Drexel University - Event Details View - Lubrication by Polyelectrolytes - Ionic Strength, Valency and Geometry
Dr. Lin Han, assistant professor in BIOMED, will discuss how polyelectrolytes effectively reduce surface friction by decreasing surface contact adhesion, and creating a fluid-like hydration sheath surrounding charged groups. Utilizing lateral force microcopy, Dr. Han and his team investigated the mechanisms and environmental factors that can quantitatively control the magnitude of polyelectrolyte surface friction coefficient, μ, at nano- to micrometer deformation length scales. In the first model system, with a microspherical tip, lateral force microscopy was utilized to measure the friction of an end-attached monolayer of the comb-like, negatively charged, biomacromolecules extracted from articular cartilage, aggrecan. In a second model system, we studied the layer-by-layer assembled poly(allylamine hydrochloride) / poly(acrylic acid) (PAH/PAA) in various microscale geometries (planar film versus tube forest). Understanding these environmental factors provides a platform to design dynamic substrates
http://events.drexel.edu/EventList.aspx?view=EventDetails&eventidn=2888&information_id=9951
Nano-Molar Deltamethrin Sensor Based on Electrical Impedance of PAH/PAZO Layer-by-Layer Sensing Films - ScienceOpenNano-Molar Deltamethrin Sensor Based on Electrical Impedance of PAH/PAZO Layer-by-Layer Sensing Films - ScienceOpen
This work reports a novel deltamethrin (DM) sensor able to detect nano-molar concentrations in ethanol solutions. The sensing layer consists of a thin film, obtained via a layer-by-layer technique, from alternate adsorption of poly(allylamine chloride) (PAH) and poly[1-[4-(3-carboxy-4-hydroxyphenylazo)-benzenesulfonamide)-1,2-ethanediyl]sodium salt] (PAZO) onto a solid support with interdigitaded gold electrodes. The sensor response, obtained from impedance spectroscopy measurements, was revealed to be linear with respect to the real part of impedance, taken at 100 Hz, when plotted as a function of the logarithm of deltamethrin molar concentrations in the micro- to nano-molar range. Sensor sensitivity was of 41.1 ± 0.7 kΩ per decade of concentration for an immersion time above 2 min and the reproducibility is approximately 2% in a binary solution of ethanol and deltamethrin. The main insight of this work concerns to DM detection limits as the sensor revealed to be able to detect concentrations below
https://www.scienceopen.com/document?vid=4eafbb28-5d9f-4b9e-8077-cbab233feb35
September 2018 - Best Skin Care
Overview of Services Tinea versicolor can be successfully treated with various agents. [30] Effective topical agents include selenium sulfide, zinc-pyrithione, sodium sulfacetamide, ciclopirox olamine, [31] , tacrolimus, [32] as well as azole and allylamine antifungals. [33, 34, 35, 36, 37] Even if a small area of skin is involved, treating with topicals from the neck to the knees may make treatment more successful. [14] Various regimens can be used. Selenium sulfide lotion is liberally applied to affected areas of the skin daily for 2 weeks; each application is allowed to remain on the skin for at least 10 minutes prior to being washed off. In resistant cases, overnight application can be helpful. Topical azole antifungals can be applied every night for 2 weeks. Weekly application of any of the topical agents for the following few months may help prevent recurrence. In patients with widespread disease, some topical antifungal therapy can be expensive. Over-the-counter shampoo formulations of ...
http://bestskincare101.com/2018/09/
Zetaclear In Micronesia | Toenail Fungus Treatment Guide
Triazole and allylamine antifungal drugs have mostly replaced griseofulvin and ketoconazole as first-line medications in the therapy of nail fungus. Making use
https://fungustreatmentguide.com/zetaclear-in-micronesia/
Teva, APP develop generic Gemzar - Drug Store NewsTeva, APP develop generic Gemzar - Drug Store News
Watson, through subsidiary Watson Labs, said it applied for approval of a generic version of Daiichi Sankyos and Genzymes Welchol (colesevelam hydrochloride). The drug, a powdered oral suspension, is used to reduce bad LDL cholesterol in patients with primary hyperlipidemia, either alone or in combination with a statin.. Watsons application included a Paragraph IV certification, a legal assertion that the patents covering Welchol are invalid, unenforceable or not vulnerable to infringement. Under the terms of the Hatch-Waxman Act of 1984, Daiichi Sankyo and Genzyme have filed suit against Watson in the U.S. District Court for the District of Delaware, putting a stay of final Food and Drug Administration approval on the drug until June 2013, or until the companies reach a settlement.. ...
https://www.drugstorenews.com/article/teva-app-develop-generic-gemzar/?ad=generics
The Farnesoid X Receptor | Arteriosclerosis, Thrombosis, and Vascular BiologyThe Farnesoid X Receptor | Arteriosclerosis, Thrombosis, and Vascular Biology
A first piece of evidence for a link between bile acid and glucose metabolism came from a short-term study in patients with noninsulin-dependent diabetes mellitus (NIDDM) or type II diabetes.114 Patients with high LDL cholesterol but normal triglyceride levels, using either glyburide or insulin to control glycemia, were treated with cholestyramine or placebo. Cholestyramine treatment lowered plasma glucose by 13% and decreased urinary glucose excretion, with a tendency toward lower glycosylated hemoglobin concentrations. At the same time, cholestyramine reduced total and LDL cholesterol and increased triglyceride levels. This study therefore identified bile acid sequestrants, which are not absorbed, as a potential option to treat type II diabetes. It will be of interest to determine whether the ASBT inhibitors, like S 8921115 or SC 435,116 that selectively interfere with bile acid reabsorption also regulate glycemia in diabetic patients. Nevertheless, because an increase of unbound bile acids ...
http://atvb.ahajournals.org/content/25/10/2020.full
Familial hypercholesterolemia - WikipediaFamilial hypercholesterolemia - Wikipedia
FH is usually treated with statins.[7] Statins act by inhibiting the enzyme hydroxymethylglutaryl CoA reductase (HMG-CoA-reductase) in the liver. In response, the liver produces more LDL receptors, which remove circulating LDL from the blood. Statins effectively lower cholesterol and LDL levels, although sometimes add-on therapy with other drugs is required, such as bile acid sequestrants (cholestyramine or colestipol), nicotinic acid preparations or fibrates.[2] Control of other risk factors for cardiovascular disease is required, as risk remains somewhat elevated even when cholesterol levels are controlled. Professional guidelines recommend that the decision to treat a person with FH with statins should not be based on the usual risk prediction tools (such as those derived from the Framingham Heart Study), as they are likely to underestimate the risk of cardiovascular disease; unlike the rest of the population, FH have had high levels of cholesterol since birth, probably increasing their ...
https://en.m.wikipedia.org/wiki/Familial_hypercholesterolemia
Kail - WikipediaKail - Wikipedia
Beta carotene, vitamin K, vitamin C, an calcium is rowth in kail. Kail is a soorce o twa carotenoids, lutein an zeaxanthin.[1] Kail, as wi broccoli an ither brassicas, conteens sulforaphane (parteecular whan its been chappit or minced), a chemical wi potent anti-cancer properties.[2] Bylin lawers the leevel o sulforaphane; housomeiver, steamin, microwavin, or stir fryin disna cause a important loss.[3] Lik ither brassica vegetables, kail is a soorce o indole-3-carbinol an aw, a chemical that forders DNA repair in cells an appears tae keep cancer cells fae growin.[4][5] Kail haes been foond tae conteen a group o resins cried bile acid sequestrants, that haes been shawn tae lawer cholesterol an lawer absorption o dietary fat. Steamin signeeficantly accresses thir bile acid bindin properties.[6] ...
https://sco.wikipedia.org/wiki/Kail
RCSB PDB - 5TZ1: Crystal structure of sterol 14-alpha demethylase (CYP51) from Candida albicans in complex with the...RCSB PDB - 5TZ1: Crystal structure of sterol 14-alpha demethylase (CYP51) from Candida albicans in complex with the...
5TZ1: Structural analyses of Candida albicans sterol 14 alpha-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis.
http://www.rcsb.org/pdb/explore/explore.do?structureId=5TZ1
In vitro and in vivo antidermatophyte activities of NND-502, a novel optically active imidazole antimycotic agent - Fingerprint...
Fingerprint Dive into the research topics of In vitro and in vivo antidermatophyte activities of NND-502, a novel optically active imidazole antimycotic agent. Together they form a unique fingerprint. ...
https://tohoku.pure.elsevier.com/en/publications/in-vitro-and-in-vivo-antidermatophyte-activities-of-nnd-502-a-nov/fingerprints/
Diego Gallardo: The Key Mass-Building Move (Not What You Think)Diego Gallardo: The Key Mass-Building Move (Not What You Think)
With Dougs comments and revisiting all of the above, Im going to experiment again with putting the stretch-position exercise first in my bodypart routines. I say again because we tried that years ago. In fact, it worked so well we created a video titled Hypercontraction Training. Lots of trainees reported excellent mass gains-but it fell out of favor. Why? Because strength was sluggish on the big midrange exercises, which were performed after a few sets of a stretch-position exercise. We thought because strength wasnt increasing, it wasnt working well. Wrong… ...
http://www.diegogallardo.com/2016/01/the-key-mass-building-move-not-what-you.html
AllylamineAllylamine
"Synthesis of allylamine in ethanol". ResearchGate. Retrieved 2020-06-30. M. T. Leffler (1938). "Allylamine". Organic Syntheses ... Functionalized allylamines have pharmaceutical applications. Pharmaceutically important allylamines include flunarizine and ... Allylamine, like other allyl derivatives is a lachrymator and skin irritant. Its oral LD50 is 106 mg/kg for rats. Nomenclature ... Allylamine is an organic compound with the formula C3H5NH2. This colorless liquid is the simplest stable unsaturated amine. All ...
https://en.wikipedia.org/wiki/Allylamine
Allyl isothiocyanateAllyl isothiocyanate
Hydrolysis of allyl isothiocyanate gives allylamine. Allyl isothiocyanate has an LD50 of 151 mg/kg and is a lachrymator ( ... Leffler, M. T. (1938). "Allylamine". Organic Syntheses. 18: 5.; Collective Volume, vol. 2, p. 24 Zhang, Y (2010). "Allyl ...
https://en.wikipedia.org/wiki/Allyl_isothiocyanate
Topical antifungal drugsTopical antifungal drugs
"Figure 1. Structures of antifungal allylamines". ResearchGate. Retrieved 2022-04-23. "Allylamine - an overview , ScienceDirect ... Mechanism of action Allylamines are a new type of antifungal drug that is highly selective for the fungal enzyme but has a ... Allylamines allow the active ingredients in the medication to accumulate well within the stratum corneum of the skin and nails ... Similar to azoles, allylamines disrupt the fungal cell wall synthesis through inhibition of the squalene epoxidase enzyme that ...
https://en.wikipedia.org/wiki/Topical_antifungal_drugs
TriallylamineTriallylamine
Allylamines have particularly weak α-CH bonds, being near 80 kcal/mol. Allylamine Diallylamine "Triallylamine". pubchem.ncbi. ...
https://en.wikipedia.org/wiki/Triallylamine
DiallylamineDiallylamine
Allylamine Triallylamine "Diallylamine". pubchem.ncbi.nlm.nih.gov. Retrieved 2 March 2022. Eller, Karsten; Henkes, Erhard; ...
https://en.wikipedia.org/wiki/Diallylamine
NaftifineNaftifine
... hydrochloride (brand names include Exoderil and Naftin) is an allylamine antifungal drug for the topical treatment of ... It was the first successful antifungal medication of the allylamine class. Naftifine has triple action: antifungal, ... Mühlbacher JM (1991). "Naftifine: a topical allylamine antifungal agent". Clinics in Dermatology. 9 (4): 479-85. doi:10.1016/ ...
https://en.wikipedia.org/wiki/Naftifine
MaleimideMaleimide
Lin, K.-F.; Lin, J.-S.; Cheng, C.-H. (1996). "High temperature resins based on allylamine/bismaleimides". Polymer. 37 (21): ...
https://en.wikipedia.org/wiki/Maleimide
Polyallylamine hydrochloridePolyallylamine hydrochloride
Poly(allylamine hydrochloride) has many biomedical applications. The most prominent use of this polyelectrolyte is in the field ... 71550-12-4) is a cationic polyelectrolyte prepared by the polymerization of allylamine. It can be used in combination with an ...
https://en.wikipedia.org/wiki/Polyallylamine_hydrochloride
PolyelectrolytePolyelectrolyte
An LbL formation of PEM (PSS-PAH (poly(allylamine) hydrochloride)) on a gold substrate can be seen in the Figure. The formation ... "Metal Complexes of Amphoteric Cryogels Based on Allylamine and Methacrylic Acid". Macromolecular Symposia. 317-318: 18-27. doi: ...
https://en.wikipedia.org/wiki/Polyelectrolyte
ButenafineButenafine
Like the allylamine antifungals, butenafine works by inhibiting the synthesis of ergosterol by inhibiting squalene epoxidase, ... It is structurally related to synthetic allylamine antifungals such as terbinafine. Butenafine is indicated for the topical ...
https://en.wikipedia.org/wiki/Butenafine
TerbinafineTerbinafine
... is in the allylamines family of medications. It works by decreasing the ability of fungi to synthesize sterols. It ... Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that catalyzes ...
https://en.wikipedia.org/wiki/Terbinafine
HydroaminationHydroamination
Both systems produced the desired allyl amines in high yield, which contain an alkene that can be further functionalized ... The isolation and characterization of the rarer and more synthetically valuable kinetic allyl amine product was reported when ... Functionalized allylamines, which can be produced through hydroamination, have extensive pharmaceutical application, although ... Hydroamination has been utilized to synthesize the allylamine Cinnarizine in quantitative yield. Cinnarizine treats both ...
https://en.wikipedia.org/wiki/Hydroamination
Aminoallyl nucleotideAminoallyl nucleotide
Its formation can be associated with a reaction with an allylamine and various reagents via heck coupling are able to remove ... Aminoallyl nucleotide is a nucleotide with a modified base containing an allylamine. They are used in post-labeling of nucleic ... the halogen group from the base and add the allylamine to become the aminoallyl nucleoside shown on the right. The product on ...
https://en.wikipedia.org/wiki/Aminoallyl_nucleotide
AlmitrineAlmitrine
Reaction with Allylamine [107-11-9] (4) completes the synthesis of Almitrine (5). Flunarizine Diphenylmethylpiperazine Servier ...
https://en.wikipedia.org/wiki/Almitrine
Kristy M. AinslieKristy M. Ainslie
... allylamine) thin films". Langmuir. 23 (13): 7018-23. doi:10.1021/la7004997. PMID 17506587. Ainslie, Kristy; Sharma, Gurav; Dyer ...
https://en.wikipedia.org/wiki/Kristy_M._Ainslie
Claisen rearrangementClaisen rearrangement
Nubbemeyer, U. (1995). "1,2-Asymmetric Induction in the Zwitterionic Claisen Rearrangement of Allylamines". J. Org. Chem. 60 ( ...
https://en.wikipedia.org/wiki/Claisen_rearrangement
CyclopropeneCyclopropene
CH2=CHCH2Cl + NaNH2 → C3H4 (cyclopropene) + NaCl + NH3 The major byproduct of the reaction is allylamine. Adding allyl chloride ...
https://en.wikipedia.org/wiki/Cyclopropene
Penicillium sclerotigenumPenicillium sclerotigenum
... allylamine hydrochloride) composite". Journal of Colloid and Interface Science. 396: 258-263. doi:10.1016/j.jcis.2013.01.023. ...
https://en.wikipedia.org/wiki/Penicillium_sclerotigenum
Tinea crurisTinea cruris
Studies suggest that allylamines (naftifine and terbinafine) are a quicker but more expensive form of treatment compared to ... Tinea cruris is treated by applying antifungal medications of the allylamine or azole type to the groin region. ...
https://en.wikipedia.org/wiki/Tinea_cruris
Core-shell semiconductor nanocrystalCore-shell semiconductor nanocrystal
In particular, Si quantum dots with poly (acrylic acid) and allylamine shells have been used in cell labeling. Other in vitro ...
https://en.wikipedia.org/wiki/Core–shell_semiconductor_nanocrystal
Petasis reactionPetasis reaction
In comparison to other methods of generating allyl amines, the Petasis reaction tolerates a multifunctional scaffold, with a ... Vinyl boronic acids react with the adducts of secondary amines and paraformaldehyde to give tertiary allylamines. The geometry ... the corresponding allylamine is formed as a single diastereomer. Furthermore, enantiomeric purity can be achieved by ... A new method for the synthesis of geometrically pure allylamines". Tetrahedron Lett. 34 (4): 583-586. doi:10.1016/S0040-4039(00 ...
https://en.wikipedia.org/wiki/Petasis_reaction
BorylationBorylation
... they have found that vinyl boronic acids can participate as nucleophiles to give geometrically pure allylamines. This modified ... A new method for the synthesis of geometrically pure allylamines". Tetrahedron Letters. 34 (4): 583-586. doi:10.1016/S0040-4039 ...
https://en.wikipedia.org/wiki/Borylation
Trichophyton concentricumTrichophyton concentricum
... azole and allylamine agents have not been found to be as effective in treating tinea imbricata. However, griseofulvin has not ...
https://en.wikipedia.org/wiki/Trichophyton_concentricum
TrimethylsilyldiazomethaneTrimethylsilyldiazomethane
The compound is a reagent in the Doyle-Kirmse reaction with allyl sulfides and allyl amines. Trimethylsilyldiazomethane is ...
https://en.wikipedia.org/wiki/Trimethylsilyldiazomethane
AntifungalAntifungal
"Research and Markets: Global Antifungal Therapeutics (Polyenes, Azoles, Echinocandins, Allylamines) Market:Trends and ... similar mechanism to allylamines like terbinafine)[medical citation needed] Triacetin - hydrolysed to acetic acid by fungal ... Fluconazole Isavuconazole Itraconazole Posaconazole Propiconazole Ravuconazole Terconazole Voriconazole Abafungin Allylamines ...
https://en.wikipedia.org/wiki/Antifungal
Athletes footAthlete's foot
Allylamines such as terbinafine are considered more efficacious than azoles for the treatment of athlete's foot. Severe or ...
https://en.wikipedia.org/wiki/Athlete's_foot
Fiona MeldrumFiona Meldrum
Allylamine Hydrochloride) and Magnesium Ions". Chemistry of Materials. 25 (24): 4994-5003. doi:10.1021/cm403497g. ISSN 0897- ...
https://en.wikipedia.org/wiki/Fiona_Meldrum
Overman rearrangementOverman rearrangement
The resulting allylamine structures can be transformed into many chemically and biologically important natural and un-natural ...
https://en.wikipedia.org/wiki/Overman_rearrangement
Digambara PatraDigambara Patra
... allyl amine) hydrochloride based nanocapsules: Piperine in nanocapsules accelerates encapsulation and release of curcumin and ...
https://en.wikipedia.org/wiki/Digambara_Patra
Primary-amine oxidasePrimary-amine oxidase
2008). "Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based ...
https://en.wikipedia.org/wiki/Primary-amine_oxidase
Tinea Pedis Medication: Topical imidazoles, Topical pyridones, Topical allylamines, Topical benzylamines, Oral antimycotics,...Tinea Pedis Medication: Topical imidazoles, Topical pyridones, Topical allylamines, Topical benzylamines, Oral antimycotics,...
Topical allylamines. Class Summary. Topical allylamines are effective in treating all forms of tinea pedis. In vitro, these ... Topical benzylamines are sometimes classified as a subset of allylamines. They are useful for treating patients with refractory ... Naftifine is a broad-spectrum antifungal agent and synthetic allylamine derivative. Naftifine interferes with sterol ...
https://www.medscape.com/answers/1091684-35775/which-medications-in-the-drug-class-topical-pyridones-are-used-in-the-treatment-of-tinea-pedis
Allylamine | Fisher ScientificAllylamine | Fisher Scientific
Browse a full range of Allylamine products from leading suppliers. Shop now at Fisher Scientific for all of your scientific ... Allylamine. Allylamine. Organische Verbindungen, die eine funktionelle Allylgruppe (Kohlenstoff, der mit einer Kohlenstoff- ...
https://www.fishersci.de/de/de/browse/80013964/allylamine
Analysis of CO2 Facilitation Transport Effect through a Hybrid Poly(Allyl Amine) Membrane: Pathways for Further Improvement -...Analysis of CO2 Facilitation Transport Effect through a Hybrid Poly(Allyl Amine) Membrane: Pathways for Further Improvement -...
Analysis of CO2 Facilitation Transport Effect through a Hybrid Poly(Allyl Amine) Membrane: Pathways for Further Improvement ... Analysis of CO2 Facilitation Transport Effect through a Hybrid Poly(Allyl Amine) Membrane: Pathways for Further Improvement. ...
https://hal.univ-lorraine.fr/hal-03207003
NIOSHs CBRN Respirator Approval Program | NPPTL | NIOSH | CDCNIOSH's CBRN Respirator Approval Program | NPPTL | NIOSH | CDC
Palladium-Catalyzed Regioselective Arylation of Unprotected AllylaminesPalladium-Catalyzed Regioselective Arylation of Unprotected Allylamines
Landge, Vinod G.; Maxwell, Justin M.; Chand-Thakuri, Pratibha; Kapoor, Mohit; Diemler, Evan T.; Young, Michael C ...
https://scholars.utoledo.edu/display/pub-000651111900004
Sevelamer - WikipediaSevelamer - Wikipedia
poly(allylamine-. co-N,N-diallyl-1,3-diamino-2-hydroxypropane). CAS Number. *52757-95-6 Y ...
https://en.wikipedia.org/wiki/Sevelamer
Acervo Digital: Unusual interactions binding iron tetrasulfonated phthalocyanine and poly(allylamine hydrochloride) in layer-by...Acervo Digital: Unusual interactions binding iron tetrasulfonated phthalocyanine and poly(allylamine hydrochloride) in layer-by...
Unusual interactions binding iron tetrasulfonated phthalocyanine and poly(allylamine hydrochloride) in layer-by-layer films. en ... allylamine hydrochloride) (PAH) in electroactive layer-by-layer (LBL) films. These interactions have been identified by ...
https://acervodigital.unesp.br/handle/11449/36976?mode=full
Registration Dossier - ECHARegistration Dossier - ECHA
Although conducted using a method equivalent to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test), no analytical monitoring of test concentrations was conducted and there are deficiencies in the reporting compared to requirements of the modern OECD 203 Guideline. However, for the purpose of assessment of aquatic toxicity, this study will be used in a weight-of-evidence approach in conjunction with data on fish, aquatic invertebrates and aquatic algae for the puspoe of PNEC determination ...
https://echa.europa.eu/registration-dossier/-/registered-dossier/5470/6/2/10
Synthetic sulfonated derivatives of poly(allylamine hydrochloride) as inhibitors of human metapneumovirus. | PLoS One;14(3):...Synthetic sulfonated derivatives of poly(allylamine hydrochloride) as inhibitors of human metapneumovirus. | PLoS One;14(3):...
Synthetic sulfonated derivatives of poly(allylamine hydrochloride) as inhibitors of human Synthetic sulfonated derivatives of ... Previously, we reported that N-sulfonated derivatives of poly(allylamine hydrochloride) (NSPAHs) efficiently inhibit ... poly(allylamine hydrochloride) as inhibitors of human metapneumovirus. Ciejka, Justyna; Botwina, Pawel; Nowakowska, Maria; ...
https://pesquisa.bvsalud.org/portal/resource/pt/mdl-30921418
Tinea pedis: not just the curse of the athlete - BPJ65 December 2014Tinea pedis: not just the curse of the athlete - BPJ65 December 2014
Allylamine antifungals such as terbinafine are reported to be generally more effective than azole antifungals, e.g. miconazole ... Topical allylamine antifungals (terbinafine). Topical terbinafine is not subsidised on the Pharmaceutical Schedule, but is ...
https://bpac.org.nz/BPJ/2014/December/tinea-pedis.aspx
Alprostadil alfadex - CarbomerAlprostadil alfadex - Carbomer
SKU: 4-00673 Category: Other Native Semisynthetic Glycans Tag: A Cas No. : [55648-20-9]Synonym / Description : Prostglandin E1-a-cyclodextrin complexMol Formula : C56H94O35 Fw : Fw 1,327.33 Grade : Purity : ~3% Alprostadil[745-65-3] ...
https://carbomer.com/product/alprostadil-alfadex/
3-氨基丙烯；烯丙胺MSDS,3-aminopropene;allylamine MSDS,107-11-9 MSDS - MSDS网
3-氨基丙烯；烯丙胺MSDS,提供了3-氨基丙烯；烯丙胺的GHS分类,危害象形图,警示词,
https://ghs-msds.cn/msds/2074.html
Adsorption of Anti-C-Reactive Protein Monoclonal Antibody and F(ab') Fragment on Plasma-Polymerized Styrene, Allylamine and...
Adsorption of Anti-C-Reactive Protein Monoclonal Antibody and F(ab) Fragment on Plasma-Polymerized Styrene, Allylamine and ... Adsorption of Anti-C-Reactive Protein Monoclonal Antibody and F(ab) Fragment on Plasma-Polymerized Styrene, Allylamine and ... Adsorption of Anti-C-Reactive Protein Monoclonal Antibody and F(ab) Fragment on Plasma-Polymerized Styrene, Allylamine and ... Adsorption of Anti-C-Reactive Protein Monoclonal Antibody and F(ab) Fragment on Plasma-Polymerized Styrene, Allylamine and ...
https://shibaura.pure.elsevier.com/en/publications/adsorption-of-anti-c-reactive-protein-monoclonal-antibody-and-fab
Rule 3745-114-01 - Ohio Administrative Code | Ohio LawsRule 3745-114-01 - Ohio Administrative Code | Ohio Laws
allylamine. 00107-11-9. aluminum & compounds, as Al; Metal dust; Pyro powders Soluble salts; Alkyls (NOS). 07429-90-5. ...
https://codes.ohio.gov/ohio-administrative-code/rule-3745-114-01
NIOSHTIC-2 Search Results - Basic View
Antifungal Drugs Market and Factors Behind its Growing Landscape - Industry Analysis by Top Vendors, Size, Growth Factors and...Antifungal Drugs Market and Factors Behind its Growing Landscape - Industry Analysis by Top Vendors, Size, Growth Factors and...
Allylamines. *Azoles. *Others. *Global Antifungal Drugs Market, By Indication, 2016 - 2027, (US$ million) *Introduction *Market ...
https://www.pharmiweb.com/press-release/2021-03-02/antifungal-drugs-market-and-factors-behind-its-growing-landscape-industry-analysis-by-top-vendors
Full publication list | Max Planck Institute for Polymer ResearchFull publication list | Max Planck Institute for Polymer Research
van Os, M. T.; Menges, B.; Förch, R.; Knoll, W.; Timmons, R. B.; Vancso, G. J.: Thin film plasma deposition of allylamine; ... van Os, M. T.; Menges, B.; Foerch, R.; Vancso, G. J.; Knoll, W.: Characterization of Plasma-Polymerized Allylamine Using ... Variations in the Film Chemistry of Pulsed RF Plasma Deposited Allylamine. In: 13th International Symposium on Plasma Chemistry ...
https://www.mpip-mainz.mpg.de/publication-search/31384?page=4&person=%2Fpersons%2Fresource%2Fpersons47885
Nanostructured carbon-based membranes: nitrogen doping effects on reverse osmosis performance | NPG Asia MaterialsNanostructured carbon-based membranes: nitrogen doping effects on reverse osmosis performance | NPG Asia Materials
Hinman, P. V., Bell, A. T. & Shen, M. Composite reverse osmosis membranes prepared by plasma polymerization of allylamine. ... Reverse osmosis characteristics of composite membranes prepared by plasma polymerization of allylamine. Effects of deposition ...
https://www.nature.com/articles/am201627?error=cookies_not_supported&code=ab0869ed-8bf2-49cd-ba94-dbeef73072de
Emericella quadrilineata as Cause of Invasive Aspergillosis - Volume 14, Number 4-April 2008 - Emerging Infectious Diseases...
Although the allylamine terbinafine is not used for treatment of patients with invasive aspergillosis, the drug is highly ...
https://wwwnc.cdc.gov/eid/article/14/4/07-1157_article
Amit Jaiswal - Google ScholarAmit Jaiswal - Google Scholar
Poly(allylamine hydrochloride) functionalized reduced graphene oxide for synergistic chemo-photothermal therapy. S Roy, A ...
https://scholar.google.co.in/citations?user=SxIMTwIAAAAJ&hl=en
US Patent for Filter medium for selectively removing leucocytes Patent (Patent # 4,936,998 issued June 26, 1990) - Justia...US Patent for Filter medium for selectively removing leucocytes Patent (Patent # 4,936,998 issued June 26, 1990) - Justia...
Examples of monomers containing nitrogen-containing basic functional groups include allylamine; (meth)acrylic acid derivatives ... having a nitrogen-containing basic functional group is selected from vinyl compounds of the group consisting of allylamine, ( ... having a nitrogen-containing basic functional group is selected from vinyl compounds of the group consisting of allylamine, ( ...
https://patents.justia.com/patent/4936998
AF TER Cream 30gm - Buy Medicines online at Best Price from Netmeds.comAF TER Cream 30gm - Buy Medicines online at Best Price from Netmeds.com
Terbinafine is an allylamine which has a broad spectrum of antifungal activity. At low concentrations it is fungicidal against ...
https://www.netmeds.com/prescriptions/af-ter-cream-30gm
Phosphate BinderPhosphate Binder
sevelamer, sevelamer [Chemical/Ingredient], SEVELAMER, Sevelamer (product), Sevelamer (substance), Sevelamer, poly(allylamine- ...
https://fpnotebook.com/legacy/Renal/Pharm/PhsphtBndr.htm
COVID-19 Detection Test Kits and Consumables Market Analysis, Size And Trends Global Forecast To 2022-2030COVID-19 Detection Test Kits and Consumables Market Analysis, Size And Trends Global Forecast To 2022-2030
The main types of drugs in antifungals are echinocandins, azoles, polyenes, and allylamines. Echinocandins are a new type of ... The global antifungals market is segmented - 1) By Drug Type: Echinocandins, Azoles, Polyenes, Allylamines 2) End users: ... Antifungals Global Market Report 2022 - By Drug Type (Echinocandins, Azoles, Polyenes, Allylamines), By End users (Hospitals & ... Antifungals Global Market Report 2022 - By Drug Type (Echinocandins, Azoles, Polyenes, Allylamines), By End users (Hospitals & ...
https://www.thebusinessresearchcompany.com/report/covid-19-detection-test-kits-and-consumables-global-market-report
Human Metabolome Database: HMDB0014918 (Phenelzine) Protein AssociationsHuman Metabolome Database: HMDB0014918 (Phenelzine) Protein Associations
Kumar D, Trent MB, Boor PJ: Allylamine and beta-aminopropionitrile induced aortic medial necrosis: mechanisms of synergism. ...
https://hmdb.ca/metabolites/HMDB0014918/metabolite_protein_links
Wissenschaftliche Publikationen des Instituts | Max-Planck-Institut für Kolloid- und Grenzflächenforschung
Publikationen | Max-Planck-Institut für KohlenforschungPublikationen | Max-Planck-Institut für Kohlenforschung
Cheng, Q.; Chen, J.; Lin, S.; Ritter, T. Allylic Amination of Alkenes with Iminothianthrenes to Afford Alkyl Allylamines. ...
https://www.kofo.mpg.de/publication-search/277047?person=%2Fpersons%2Fresource%2Fpersons214485
TerbinafinePolyAzolesTopicalAntifungal drugsSyntheticBenzylaminesTineaEffectiveAgentsPolyTerbinafineSyntheticAntifungal AgentsPolymersVascular smooth musclPlasma-polymerizedAcrylic acidSqualeneAntimycoticsToxinVivoVitroRatsAorticGlutathioneTreatmentProteinActivityPRODUCTSWater
Terbinafine4
  • Terbinafine is an allylamine which has a broad spectrum of antifungal activity. (netmeds.com)
  • The allylamine antifungal compound can be terbinafine or naftifine. (epo.org)
  • Terbinafine is a member of the allylamine family, fungicidal agents that inhibit ergosterol synthesis by means of squalene epoxidase. (medscape.com)
  • The allylamine terbinafine, which selectively inhibits squalene epoxidase Erg1 within the ergosterol biosynthetic pathway, is mainly used to treat dermatomycoses, whereas its effectiveness in other fungal infections is limited. (fecyt.es)
Poly4
  • Molecular-level interactions are found to bind iron tetrasulfonated phthalocyanine (FeTsPc) and the polyelectrolyte poly(allylamine hydrochloride) (PAH) in electroactive layer-by-layer (LBL) films. (unesp.br)
  • Synthetic sulfonated derivatives of poly(allylamine hydrochloride) as inhibitors of human metapneumovirus. (bvsalud.org)
  • Previously, we reported that N-sulfonated derivatives of poly( allylamine hydrochloride) (NSPAHs) efficiently inhibit replication of the influenza virus in vitro and ex vivo. (bvsalud.org)
  • Nanoporous thin films formed by salt-induced structural changes in multilayers of poly(acrylic acid) and poly(allylamine). (mpg.de)
Azoles1
  • The 2 classes of antifungal medication most commonly used to treat tinea faciei in practice are azoles and allylamines. (medscape.com)
Topical1
  • Treatments available with the indication of Malassezia overgrowth include both systemic treatment with azole derivatives or allylamine and a wide variety of agents for topical treatment. (slu.se)
Antifungal drugs1
  • The drug is an outstanding representative of allylamine subgroup of antifungal drugs. (zenidol.at)
Synthetic1
  • Naftin Cream is a synthetic allylamine derivative while Ketoconazole is an imidazole antifungal agent. (prescriptionpoint.com)
Benzylamines1
Tinea1
  • NAFTIN GEL 2% is an allylamine antifungal indicated for the treatment of interdigital tinea pedis caused by the organisms Trichophyton rubrum , Trichophyton mentagrophytes , and Epidermophyton floccosum in patients 12 years of age and older. (naftin.com)
Effective1
  • The approach from the allylamine subgroup is effective against mold and yeast microorganisms. (zenidol.at)
Agents1
  • 10 But NAFTIN GEL 2% is an allylamine, which means it is chemically distinct from azole-based antifungal agents. (naftin.com)
Poly18
  • Poly (Allylamine Hydrochloride)" is the name of one of the most useful polymers. (chemistrylearner.com)
  • However, the most important use of Poly (Allylamine Hydrochloride) is in Cell Encapsulation. (chemistrylearner.com)
  • Poly(allylamine hydrochloride) was also grafted with phenyl azido groups and used as photoreactive polycations for LbL assembly. (phys.org)
  • 6. Black phosphorus nanosheets/poly(allylamine hydrochloride) based electrochemical immunosensor for the selective detection of human epididymis protein 4. (nih.gov)
  • Nanoporous thin films formed by salt-induced structural changes in multilayers of poly(acrylic acid) and poly(allylamine). (mpg.de)
  • The effect of salt on the behaviour of bovine serum albumin (BSA) in solution and on the interactions between BSA and the weakly charged polyelectrolytes poly(allylamine hydrochloride) and poly(dimethylaminoethylmethacrylate) was investigated by potentiometric titrations. (srce.hr)
  • The interaction of DNA with 5,10,15,20-tetrakis(4-N-methylpyridiniumyl)porphyrin (TMPyP) in polyelectrolyte core-shells obtained via layer by layer adsorption of poly(sodium 4-styrenesulfonate), PSS, and poly(allylamine hydrochloride), PAH, polyelectrolytes was followed by steady state, time resolved spectroscopy and by Fluorescence Lifetime Imaging Microscopy (FLIM). (jascoinc.com)
  • An evanescent-wave optical fibre sensor modified with tetrakis(4-sulfophenyl)porphine (TSPP) and poly(allylamine hydrochloride) (PAH) bilayers using an layer-by-layer (LbL) approach was tested to measure the gas emitted from human skin. (spie.org)
  • To address this problem, single-walled carbon nanotubes modified with poly (allylamine hydrochloride) (PAH/Ox-SWCNT) composite were synthesized and applied as an adsorbent for arsenic removal from aqueous solution in this study. (wwjournal.ir)
  • The layer-by-layer method was used to coat 30mm of the central unclad section of a multimode polymeric optical fibre with 7 layers of a hydrophilic film consisting of bilayers of poly(allylamine hydrochloride) and SiO2 mesoporous nanoparticles. (nottingham.ac.uk)
  • Modification with poly(acrylic acid) which has a similar structure to poly(acrylamide) also shows some enhancement in activity but is unstable, whereas poly(allylamine) completely suppresses CO2 reduction in favor of the hydrogen evolution reaction. (swan.ac.uk)
  • Drastic enhancement of carbon dioxide adsorption in fluoroalkyl-modified poly(allylamine) by: Marco Taddei, et al. (swan.ac.uk)
  • As cationic counterpart to form the anionic-cationic bilayer, different polyelectrolytes acting as the polymeric matrices embedding the sensing material have been studied: poly(diallyldimethylammonium chloride) (PDDA), polyethyleneimine (PEI) and poly(allylamine hydrochloride) (PAH). (uea.ac.uk)
  • Sevelamer carbonate is known chemically as poly(allylamine-co-N,N'-diallyl-1,3 diamino-2-hydroxypropane) carbonate salt. (semperfidelishealthcare.com)
  • We have fabricated polyelectrolyte multilayer films on gold, using poly(allylamine hydrochloride) (PAH) as the polycation and poly(acrylic acid) (PAA) as the polyanion. (elsevier.com)
  • Poly(allylamine hydrochloride) was added to flip the surface charge of the particles from negative to positive as well as to serve as a stabilizing agent. (linfield.edu)
  • Characterization data suggest that the particles are successfully coated with both poly(allylamine hydrochloride) and lipids and that monodispersity was maintained, as evidenced by the measured changes in size and optical properties. (linfield.edu)
  • The large selection of basic polymers at Alfa Chemistry covers amine-functional polymers, such as allylamines, ethylenimines, oxazolines, as well as other amine polymers attached to the major or side chains, including poly(2-oxazoline), polyethyleneimine, and others. (rippeynews.org)
Terbinafine14
  • Naftifine, the original member of the allylamine series, possesses only topical activity, whereas the naftifine analog terbinafine is active both topically and orally. (nih.gov)
  • Effects of naftifine and terbinafine, two allylamine antifungal drugs, on selected functions of human polymorphonuclear leukocytes. (nih.gov)
  • Terbinafine tablets are an allylamine antifungal indicated for the treatment of onychomycosis of the toenail or fingernail due to dermatophytes (tinea unguium). (nih.gov)
  • LAMISIL® (terbinafine hydrochloride tablets) Tablets contain the synthetic allylamine antifungal compoundterbinafine hydrochloride. (druglib.com)
  • Terbinafine is an allylamine that exhibits anticancer, antifungal, and anti-hyperlipidemic activities. (lktlabs.com)
  • For the medical management of superficial and localized tinea corporis , topical azoles (eg, clotrimazole , ketoconazole ) and allylamines (eg, terbinafine , naftifine ) can be used to treat the affected area twice daily for 1-6 weeks on the basis of clinical response. (medscape.com)
  • Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. (herokuapp.com)
  • Terbinafine/Lamisil is a synthetic allylamine derivative that inhibits squalene epoxidase, a key enzyme in sterol biosynthesis in fungi. (ubacare.com)
  • Lamisil contains terbinafine, an allylamine which has a broad spectrum of antifungal activity. (dermatologyhandbook.co.uk)
  • Terbinafine (Terbiface 500) 500 mg tablet is a synthetic allylamine antifungal used to treat various fungal infections of the fingernails, toenails and skin. (healingpharma.net)
  • Terbinafine is an allylamine derivative that has a broad spectrum of antifungal activity against pathogens of the skin, hair, and nails. (healingpharma.net)
  • Terbinafine is an Allylamine antifungal drug that produces its action by killing the fungi which are responsible for infections. (drugcarts.com)
  • Terbinaforce Dusting Powder contains Terbinafine 1% w/w is an Allylamine antifungal drug that produces its action by inhibiting the growth of fungi by destroying the cell membrane this helps to treat skin infection. (drugcarts.com)
  • Terbinafine is an allylamine antifungal indicated for the treatment of onychomycosis of the toenail or fingernail due to dermatophytes, ringworm infections (including tinea pedis, cruris and corporis) where oral therapy appropriate (due to site, severity or extent). (gafacom.website)
Synthetic3
  • Allylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidase. (nih.gov)
  • Naftifine Hydrochloride is a synthetic allylamine derivative. (nih.gov)
  • To study the complex interaction between oxidative injury and the pathogenesis of vascular disease, vascular gene expression was examined in male Sprague-Dawley rats given 35 or 70:mg/kg allylamine, a synthetic amine converted to acrolein and hydrogen peroxide within the vascular wall. (houstonmethodist.org)
Antifungal Agents1
  • Clinical cure of an uncomplicated tinea cruris infection usually can be achieved using topical antifungal agents of the imidazole or allylamine family. (medscape.com)
Polymers2
  • Homopolymers and Co-polymers can be prepared by Polymerization of Allylamine. (chemistrylearner.com)
  • A new strategy to modulate the electrocatalytic activity of copper towards CO2 reduction involving adsorption of acrylamide, acrylic acid and allylamine polymers is presented. (swan.ac.uk)
Vascular smooth muscl1
  • Williams, ES, Wilson, E & Ramos, KS 2012, ' NF-κB and matrix-dependent regulation of osteopontin promoter activity in allylamine-activated vascular smooth muscle cells ', Oxidative Medicine and Cellular Longevity . (elsevier.com)
Plasma-polymerized1
  • The surfaces of plasma-polymerized (pp-) films from styrene, allylamine and acrylic acid were characterized by means of contact angle measurement. (elsevier.com)
Acrylic acid3
  • Styrene, allylamine and acrylic acid were polymerized by plasma polymerization technique under the ninth polymerization condition from 100 W and 50 Pa to 200 W and 150 Pa. (elsevier.com)
  • The values of contact angle of pp-styrene, pp-allylamine and pp-acrylic acid were widely scattered under the initial stage of nine polymerization conditions. (elsevier.com)
  • However, these values after 40 days storage under vacuum condition always converged into 87° for pp-styrene, 67° for pp-allylamine and 28° for pp-acrylic acid, respectively. (elsevier.com)
Squalene1
  • The allylamines are a new class of antifungal drugs that inhibit ergosterol synthesis at the level of squalene epoxidase. (nih.gov)
Antimycotics1
Toxin2
  • Allylamine (AA) is a cardiovascular toxin that causes lesions resembling atherosclerosis in several mammalian species. (utmb.edu)
  • In vivo metabolism of the cardiovascular toxin, allylamine. (cdc.gov)
Vivo1
  • Repeated cycles of oxidative injury by allylamine in vivo induce a proliferative rat vascular (aortic) smooth muscle cell (vSMC) phenotype characterized by matrix-dependent enhancement of mitogenic sensitivity, changes in cell surface integrin expression, and osteopontin (opn) overexpression. (elsevier.com)
Vitro1
  • This in vitro profile is reflected by the clinical effectiveness of this allylamine in the treatment of dermatophyte infections. (nih.gov)
Rats1
  • Urine samples from allylamine treated rats contained fairly constant amounts of OHPrMCA, 43.8 to 48.2 percent of the dose being excreted during the first 24 hours and 3 percent during the second 24 hour period. (cdc.gov)
Aortic1
  • To evaluate mechanisms of gene dysregulation, cultured aortic smooth muscle cells were challenged with allylamine or its metabolites and processed for molecular analysis. (houstonmethodist.org)
Glutathione1
  • Vascular lesions and extensive vascular remodeling, coupled to increased production of 8-epi-PGF2α, nuclear localization of NFκB, and alterations in glutathione homeostasis, were observed in animals treated with allylamine for up to 20:days. (houstonmethodist.org)
Treatment1
  • Allylamine is used as antifungal medicine for the treatment of skin and scull ringworm. (chemistrylearner.com)
Protein1
  • Matrix-specific changes in cellular Rel protein expression were observed in allylamine vSMCs. (elsevier.com)
Activity3
  • Here, we show that constitutive and mitogen-stimulated NF-κB DNA binding activity is enhanced in allylamine vSMCs. (elsevier.com)
  • The NF-κB DNA binding element located at -1943 in the 5()-UTR strongly inhibited opn promoter activity in allylamine vSMCs, and this response was regulated by the extracellular matrix. (elsevier.com)
  • Constitutive increases in opn promoter activity were only seen when allylamine cells were seeded on a fibronectin substrate, and this response was independent of the NF-B DNA binding sequence within the regulatory region. (elsevier.com)
PRODUCTS1
  • IP, network article, les products devices site nuestras bonds 8-bromo-9-butenylpurines attention tips techniques, la value et allylamine de sure profile et la de propulsion approach. (tonkel.de)
Water1
Sevelamer - Wikipedia
Sevelamer - Wikipedia (en.wikipedia.org)
NIOSH's CBRN Respirator Approval Program | NPPTL | NIOSH | CDC
NIOSH's CBRN Respirator Approval Program | NPPTL | NIOSH | CDC (cdc.gov)
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Tinea pedis: not just the curse of the athlete - BPJ65 December 2014
Tinea pedis: not just the curse of the athlete - BPJ65 December 2014 (bpac.org.nz)
Alprostadil alfadex - Carbomer
Alprostadil alfadex - Carbomer (carbomer.com)
Full publication list | Max Planck Institute for Polymer Research
Full publication list | Max Planck Institute for Polymer Research (mpip-mainz.mpg.de)
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Nanostructured carbon-based membranes: nitrogen doping effects on reverse osmosis performance | NPG Asia Materials
Nanostructured carbon-based membranes: nitrogen doping effects on reverse osmosis performance | NPG Asia Materials (nature.com)
Amit Jaiswal - Google Scholar
Amit Jaiswal - Google Scholar (scholar.google.co.in)
Emericella quadrilineata as Cause of Invasive Aspergillosis - Volume 14, Number 4-April 2008 - Emerging Infectious Diseases...
Emericella quadrilineata as Cause of Invasive Aspergillosis - Volume 14, Number 4-April 2008 - Emerging Infectious Diseases... (wwwnc.cdc.gov)
AF TER Cream 30gm - Buy Medicines online at Best Price from Netmeds.com
AF TER Cream 30gm - Buy Medicines online at Best Price from Netmeds.com (netmeds.com)
COVID-19 Detection Test Kits and Consumables Market Analysis, Size And Trends Global Forecast To 2022-2030
COVID-19 Detection Test Kits and Consumables Market Analysis, Size And Trends Global Forecast To 2022-2030 (thebusinessresearchcompany.com)
Human Metabolome Database: HMDB0014918 (Phenelzine) Protein Associations
Human Metabolome Database: HMDB0014918 (Phenelzine) Protein Associations (hmdb.ca)
Research Publications
Research Publications (iiitm.ac.in)
Davidson, Michael H. | Profiles RNS
Davidson, Michael H. | Profiles RNS (profiles.uchicago.edu)
Efinaconazole 10% Topical Solution for Treatment of Onychomycosis
Efinaconazole 10% Topical Solution for Treatment of Onychomycosis (skintherapyletter.com)
Anti-Infective Agents | DrugBank Online
Anti-Infective Agents | DrugBank Online (go.drugbank.com)
How long does it take tea tree oil to kill toenail fungus
How long does it take tea tree oil to kill toenail fungus (laplatacd.org)
Hydroxybutyrate Supplement
Hydroxybutyrate Supplement (zpmxchem.com)
修士課程 - 研究成果 - Shibaura Institute of Technology
修士課程 - 研究成果 - Shibaura Institute of Technology (shibaura.pure.elsevier.com)
Find Research outputs - Augusta University Research Profiles
Find Research outputs - Augusta University Research Profiles (augusta.pure.elsevier.com)
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(emedicine.medscape.com)
(emedicine.medscape.com)
(emedicine.medscape.com)
(emedicine.medscape.com)
(emedicine.medscape.com)
(emedicine.medscape.com)
(emedicine.medscape.com)
NAFTIN® NAFTIFINE HCl 1%
NAFTIN® NAFTIFINE HCl 1% (dailymed.nlm.nih.gov)
DailyMed - TERBINAFINE HYDROCHLORIDE tablet
DailyMed - TERBINAFINE HYDROCHLORIDE tablet (dailymed.nlm.nih.gov)