Garlic: One of the Liliaceae used as a spice (SPICES) and traditional remedy. It contains alliin lyase and alliin, which is converted by alliin lyase to allicin, the pungent ingredient responsible for the aroma of fresh cut garlic.Metabolic Detoxication, Drug: Reduction of pharmacologic activity or toxicity of a drug or other foreign substance by a living system, usually by enzymatic action. It includes those metabolic transformations that make the substance more soluble for faster renal excretion.Sulfur Compounds: Inorganic or organic compounds that contain sulfur as an integral part of the molecule.Allyl CompoundsGlutathione Transferase: A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.Sulfides: Chemical groups containing the covalent sulfur bonds -S-. The sulfur atom can be bound to inorganic or organic moieties.Allium: A genus of the plant family Liliaceae (sometimes classified as Alliaceae) in the order Liliales. Many produce pungent, often bacteriostatic and physiologically active compounds and are used as VEGETABLES; CONDIMENTS; and medicament, the latter in traditional medicine.Murinae: A subfamily in the family MURIDAE, comprising the Old World MICE and RATS.Anethole Trithione: Choleretic used to allay dry mouth and constipation due to tranquilizers.Sulfinic Acids: Any of the monobasic inorganic or organic acids of sulfur with the general formula RSO(OH). (From McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)Acrylonitrile: A highly poisonous compound used widely in the manufacture of plastics, adhesives and synthetic rubber.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Propanols: Isomeric forms and derivatives of PROPANOL (C3H7OH).Vinyl CompoundsPalladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.E2F3 Transcription Factor: An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F3 regulates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis.Collective Bargaining: The process of negotiation between representatives of an employee organization, association or union, and representatives of the employer.Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Homosexuality, Male: Sexual attraction or relationship between males.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Esophagectomy: Excision of part (partial) or all (total) of the esophagus. (Dorland, 28th ed)Time Factors: Elements of limited time intervals, contributing to particular results or situations.E2F Transcription Factors: A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.Alkylation: The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.Catalysis: The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.Phosphines: Inorganic or organic compounds derived from phosphine (PH3) by the replacement of H atoms. (From Grant & Hackh's Chemical Dictionary, 5th ed)Iridium: A metallic element with the atomic symbol Ir, atomic number 77, and atomic weight 192.22.Chemistry, Organic: The study of the structure, preparation, properties, and reactions of carbon compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Alkadienes: Acyclic branched or unbranched hydrocarbons having two carbon-carbon double bonds.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Refractometry: Measurement of the index of refraction (the ratio of the velocity of light or other radiation in the first of two media to its velocity in the second as it passes from one into the other).Niobium: Niobium. A metal element atomic number 41, atomic weight 92.906, symbol Nb. (From Dorland, 28th ed)Amino Acids, SulfurSulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.Pseudomonadaceae: A family of gram-negative bacteria usually found in soil or water and including many plant pathogens and a few animal pathogens.Acetobacteraceae: A family of gram-negative aerobic bacteria consisting of ellipsoidal to rod-shaped cells that occur singly, in pairs, or in chains.Polyenes: Hydrocarbons with more than one double bond. They are a reduced form of POLYYNES.Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.Propylene Glycols: Derivatives of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.Nitrogen Compounds: Inorganic compounds that contain nitrogen as an integral part of the molecule.Heterocyclic Compounds: Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)Carbonic Acid: Carbonic acid (H2C03). The hypothetical acid of carbon dioxide and water. It exists only in the form of its salts (carbonates), acid salts (hydrogen carbonates), amines (carbamic acid), and acid chlorides (carbonyl chloride). (From Grant & Hackh's Chemical Dictionary, 5th ed)Diphosphonates: Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.Imino Pyranoses: Six-carbon pyranose sugars in which the OXYGEN is replaced by a NITROGEN atom.Geranyltranstransferase: An enzyme involved in the MEVALONATE pathway, it catalyses the synthesis of farnesyl diphosphate from isopentenyl diphosphate and dimethylallyl diphosphate.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Alendronate: A nonhormonal medication for the treatment of postmenopausal osteoporosis in women. This drug builds healthy bone, restoring some of the bone loss as a result of osteoporosis.Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.Nitrogen: An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.Resins, Plant: Flammable, amorphous, vegetable products of secretion or disintegration, usually formed in special cavities of plants. They are generally insoluble in water and soluble in alcohol, carbon tetrachloride, ether, or volatile oils. They are fusible and have a conchoidal fracture. They are the oxidation or polymerization products of the terpenes, and are mixtures of aromatic acids and esters. Most are soft and sticky, but harden after exposure to cold. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)Dental Veneers: The use of a layer of tooth-colored material, usually porcelain or acrylic resin, applied to the surface of natural teeth, crowns, or pontics by fusion, cementation, or mechanical retention.Dental Porcelain: A type of porcelain used in dental restorations, either jacket crowns or inlays, artificial teeth, or metal-ceramic crowns. It is essentially a mixture of particles of feldspar and quartz, the feldspar melting first and providing a glass matrix for the quartz. Dental porcelain is produced by mixing ceramic powder (a mixture of quartz, kaolin, pigments, opacifiers, a suitable flux, and other substances) with distilled water. (From Jablonski's Dictionary of Dentistry, 1992)Manufactured Materials: Substances and materials manufactured for use in various technologies and industries and for domestic use.Micro-Electrical-Mechanical Systems: A class of devices combining electrical and mechanical components that have at least one of the dimensions in the micrometer range (between 1 micron and 1 millimeter). They include sensors, actuators, microducts, and micropumps.Dental Prosthesis Design: The plan and delineation of dental prostheses in general or a specific dental prosthesis. It does not include DENTURE DESIGN. The framework usually consists of metal.Tooth Discoloration: Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)Dental Restoration, Temporary: A prosthesis or restoration placed for a limited period, from several days to several months, which is designed to seal the tooth and maintain its position until a permanent restoration (DENTAL RESTORATION, PERMANENT) will replace it. (From Jablonski, Dictionary of Dentistry, 1992)Tooth Preparation, Prosthodontic: The selected form given to a natural tooth when it is reduced by instrumentation to receive a prosthesis (e.g., artificial crown or a retainer for a fixed or removable prosthesis). The selection of the form is guided by clinical circumstances and physical properties of the materials that make up the prosthesis. (Boucher's Clinical Dental Terminology, 4th ed, p239)Organosilicon Compounds: Organic compounds that contain silicon as an integral part of the molecule.Cyclic S-OxidesHeterocyclic Compounds, 2-Ring: A class of organic compounds containing two ring structures, one of which is made up of more than one kind of atom, usually carbon plus another atom. The heterocycle may be either aromatic or nonaromatic.Amyloid Precursor Protein Secretases: Endopeptidases that are specific for AMYLOID PROTEIN PRECURSOR. Three secretase subtypes referred to as alpha, beta, and gamma have been identified based upon the region of amyloid protein precursor they cleave.SulfonesPyridones: Pyridine derivatives with one or more keto groups on the ring.Siloxanes: Silicon polymers that contain alternate silicon and oxygen atoms in linear or cyclic molecular structures.Receptors, Notch: A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN repeats in their cytoplasmic domains. The cytoplasmic domain of notch receptors is released upon ligand binding and translocates to the CELL NUCLEUS where it acts as transcription factor.Receptor, Notch1: A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS for multiple cellular processes. It is widely expressed during EMBRYOGENESIS and is essential for EMBRYONIC DEVELOPMENT.Carbon Disulfide: A colorless, flammable, poisonous liquid, CS2. It is used as a solvent, and is a counterirritant and has local anesthetic properties but is not used as such. It is highly toxic with pronounced CNS, hematologic, and dermatologic effects.Cobalt: A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.Gases: The vapor state of matter; nonelastic fluids in which the molecules are in free movement and their mean positions far apart. Gases tend to expand indefinitely, to diffuse and mix readily with other gases, to have definite relations of volume, temperature, and pressure, and to condense or liquefy at low temperatures or under sufficient pressure. (Grant & Hackh's Chemical Dictionary, 5th ed)Butadienes: Four carbon unsaturated hydrocarbons containing two double bonds.Polymerization: Chemical reaction in which monomeric components are combined to form POLYMERS (e.g., POLYMETHYLMETHACRYLATE).Noble Gases: Elements that constitute group 18 (formerly the zero group) of the periodic table. They are gases that generally do not react chemically.Polymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).TextilesTurbinates: The scroll-like bony plates with curved margins on the lateral wall of the NASAL CAVITY. Turbinates, also called nasal concha, increase the surface area of nasal cavity thus providing a mechanism for rapid warming and humidification of air as it passes to the lung.Epoxy Compounds: Organic compounds that include a cyclic ether with three ring atoms in their structure. They are commonly used as precursors for POLYMERS such as EPOXY RESINS.Ethylene Oxide: A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794)Cystadenoma: A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed)Poloxalene: A copolymer of polyethylene and polypropylene ether glycol. It is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.Carcinogenicity Tests: Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.Nasal Mucosa: The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells.Poloxamer: A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)

Allyl-containing sulfides in garlic increase uncoupling protein content in brown adipose tissue, and noradrenaline and adrenaline secretion in rats. (1/436)

The effects of garlic supplementation on triglyceride metabolism were investigated by measurements of the degree of thermogenesis in interscapular brown adipose tissue (IBAT), and noradrenaline and adrenaline secretion in rats fed two types of dietary fat. In Experiment 1, rats were given isoenergetic high-fat diets containing either shortening or lard with or without garlic powder supplementation (8 g/kg of diet). After 28 d feeding, body weight, plasma triglyceride levels and the weights of perirenal adipose tissue and epididymal fat pad were significantly lower in rats fed diets supplemented with garlic powder than in those fed diets without garlic powder. The content of mitochondrial protein and uncoupling protein (UCP) in IBAT, and urinary noradrenaline and adrenaline excretion were significantly greater in rats fed a lard diet with garlic powder than in those fed the same diet without garlic. Other than adrenaline secretion, differences due to garlic were significant in rats fed shortening, also. In Experiment 2, the effects of various allyl-containing sulfides present in garlic on noradrenaline and adrenaline secretion were evaluated. Administration of diallyldisulfide, diallyltrisulfide and alliin, organosulfur compounds present in garlic, significantly increased plasma noradrenaline and adrenaline concentrations, whereas the administration of disulfides without allyl residues, diallylmonosulfide and S-allyl-L-cysteine did not increase adrenaline secretion. These results suggest that in rats, allyl-containing sulfides in garlic enhance thermogenesis by increasing UCP content in IBAT, and noradrenaline and adrenaline secretion.  (+info)

Cytochrome P-450-dependent bioactivation of 1,1-dichloroethylene to a reactive epoxide in human lung and liver microsomes. (2/436)

We investigated the cytochrome P-450-dependent metabolism of 1, 1-dichloroethylene (DCE) by human lung and liver microsomes and compared the results from analogous experiments in mice. Metabolites were identified by HPLC analysis of their glutathione conjugates and/or hydrolyzed products and were detected by using [14C]DCE. The role of human CYP2E1 in the metabolic reactions was examined by comparing p-nitrophenol hydroxylase activities with levels of metabolites formed and by using the CYP2E1-selective inhibitor diallyl sulfone. The major products formed in microsomal incubations containing NADPH were the DCE-epoxide-derived glutathione conjugates 2-(S-glutathionyl)acetyl glutathione and 2-S-glutathionyl acetate. Lower levels of the acetal of 2,2-dichloroacetaldehyde were also detected. In lung samples from eight patients, the amounts of epoxide-derived conjugates formed ranged from 15.6 +/- 4.23 to 34.9 +/- 12.75 pmol/mg protein/min. The levels in murine lung were higher at 40.0 +/- 3.8 pmol/mg protein/min. In liver samples from five patients, conjugate levels ranged from 46.5 +/- 8.3 to 240.0 +/- 10. 5 pmol/mg protein/min, whereas levels in murine liver were 83.0 +/- 6.2 pmol/mg protein/min. Conjugate levels formed in human liver correlated with the relative levels of p-nitrophenol hydroxylase activity present, but this relationship was equivocal in human lung. Diallyl sulfone inhibited the formation of the glutathione conjugates (20-65%) in liver samples from all four patients, whereas only one of five human lung samples exhibited this inhibition (27%). These results demonstrated that the DCE-epoxide is a major metabolite formed by human microsomes and is mediated by CYP2E1 in liver and in some individuals in lung.  (+info)

Inhibition of nitrifiers and methanotrophs from an agricultural humisol by allylsulfide and its implications for environmental studies. (3/436)

Allylsulfide, an inhibitor of ammonia monooxygenase, was tested to determine its ability to inhibit nitrification and methane oxidation in pure cultures, in agricultural humisol enrichment cultures, and in humisol slurries. We confirmed that allylsulfide is a differential inhibitor of cultures of nitrifiers and methanotrophs at concentrations of 1 and 200 microM, respectively, which result in 50% inhibition. However, although a nitrifying enrichment culture added to sterilized humisol was inhibited 50% by 4 microM allylsulfide, 500 microM allylsulfide was necessary for 50% inhibition of the endogenous nitrifying activity in nonsterile humisol. We concluded that native nitrifiers were protected, possibly by being in colonial aggregates or sheltered microenvironments.  (+info)

Metabolism of diallyl disulfide by human liver microsomal cytochromes P-450 and flavin-containing monooxygenases. (4/436)

The metabolism of diallyl disulfide (DADS), a garlic sulfur compound, was investigated in human liver microsomes. Diallyl thiosulfinate (allicin) was the only metabolite observed and its formation followed Michaelis-Menten kinetics with a Km = 0.61 +/- 0.2 mM and a Vmax = 18.5 +/- 4.2 nmol/min/mg protein, respectively (mean +/- S.E. M., n = 4). Both flavin-containing monooxygenase and the cytochrome P-450 monooxygenases (CYP) were involved in DADS oxidation, but the contribution of CYP was predominant. The cytochrome P-450 isoforms involved in this metabolism were investigated using selective chemical inhibitors, microsomes from cells expressing recombinant CYP isoenzymes, and studying the correlation of the rate of DADS oxidation with specific monooxygenase activities of human liver microsomes. Diethyldithiocarbamate and tranylcypromine inhibited allicin formation, whereas other specific inhibitors had low or no effect. Most of the different human microsomes from cells expressing CYP were able to catalyze this reaction, but CYP2E1 showed the highest affinity with a substantial activity. Furthermore, allicin formation by human liver microsomes was correlated with p-nitrophenol hydroxylase activity, a marker of CYP2E1, and tolbutamide hydroxylase activity, a marker of CYP2C9. Among these approaches only CYP2E1 was identified in each case, which suggested that DADS is preferentially metabolized to allicin by CYP2E1 in human liver. However the minor participation of other CYP forms and flavin-containing monooxygenases is likely.  (+info)

In vivo formation and localization of 1,1-dichloroethylene epoxide in murine liver: identification of its glutathione conjugate 2-S-glutathionyl acetate. (5/436)

The hepatotoxic effects induced by 1,1-dichloroethylene (DCE) are ascribed to cytochrome P-450 (CYP) 2E1-dependent formation of metabolites including 2,2-dichloroacetaldehyde and the DCE-epoxide. The DCE metabolites detected in incubations of liver microsomes are the acetal, the hydrate of 2,2-dichloroacetaldehyde, and the epoxide-derived GSH conjugates 2-S-glutathionyl acetyl glutathione ([B]) and 2-S-glutathionyl acetate ([C]). This study was undertaken to determine whether these DCE metabolites are also formed in vivo in murine liver. HPLC analysis of cytosol isolated from the livers of mice treated with [(14)C]DCE showed that [C] was the major conjugate formed, with lower levels of formation of [B]. The acetal was not detected in the cytosol. The formation of the epoxide-derived GSH conjugates was dose-dependent at 25 to 225 mg/kg DCE and occurred coincidentally with levels of covalent binding of DCE at the same doses. The acetal and conjugates [B] and [C] were also detected in bile collected from mice treated with DCE. Pretreatment of mice with buthionine sulfoximine decreased sulfhydryl levels and formation of conjugate [C], and increased DCE binding to liver proteins. In contrast, the levels of [C] and DCE binding were both reduced significantly in mice pretreated with the CYP2E1 inhibitor diallyl sulfone. Immunohistochemical studies indicated that protein adducts and conjugate [C] were localized in centrilobular hepatocytes and corresponded with the sites where CYP2E1 resided. Pretreatment with buthionine sulfoximine increased the amount of immunostaining. However, pretreatment with diallyl sulfone markedly decreased immunostaining for [C] in the hepatocytes. These results showed that 2,2-dichloroacetaldehyde and the epoxide are formed from DCE in vivo.  (+info)

Effects of allitridi on intracellular Ca2+ concentration in isolated rat brain cells. (6/436)

AIM: To study actions of allitridi extracted from garlic on intracellular calcium in isolated rat brain cells. METHODS: Brain cells were isolated from newborn rat brain with Fura 2-AM measurements of intracellular Ca2+ concentration ([Ca2+]i). RESULTS: Allitridi 1-100 mumol.L-1 concentration-dependently blocked increases of [Ca2+]i caused by potassium chloride and sodium glutamate (Glu) with IC50 of 59.7 and 69.9 mumol.L-1 respectively. Allitridi 100 mumol.L-1 blocked norepinephrine (Nor)-induced [Ca2+]i elevation. CONCLUSION: Allitridi is an effective agent for blocking the [Ca2+]i increase caused by potassium chloride, Nor and Glu.  (+info)

Roles of horizontal gene transfer and gene integration in evolution of 1,3-dichloropropene- and 1,2-dibromoethane-degradative pathways. (7/436)

The haloalkane-degrading bacteria Rhodococcus rhodochrous NCIMB13064, Pseudomonas pavonaceae 170, and Mycobacterium sp. strain GP1 share a highly conserved haloalkane dehalogenase gene (dhaA). Here, we describe the extent of the conserved dhaA segments in these three phylogenetically distinct bacteria and an analysis of their flanking sequences. The dhaA gene of the 1-chlorobutane-degrading strain NCIMB13064 was found to reside within a 1-chlorobutane catabolic gene cluster, which also encodes a putative invertase (invA), a regulatory protein (dhaR), an alcohol dehydrogenase (adhA), and an aldehyde dehydrogenase (aldA). The latter two enzymes may catalyze the oxidative conversion of n-butanol, the hydrolytic product of 1-chlorobutane, to n-butyric acid, a growth substrate for many bacteria. The activity of the dhaR gene product was analyzed in Pseudomonas sp. strain GJ1, in which it appeared to function as a repressor of dhaA expression. The 1,2-dibromoethane-degrading strain GP1 contained a conserved DNA segment of 2.7 kb, which included dhaR, dhaA, and part of invA. A 12-nucleotide deletion in dhaR led to constitutive expression of dhaA in strain GP1, in contrast to the inducible expression of dhaA in strain NCIMB13064. The 1, 3-dichloropropene-degrading strain 170 possessed a conserved DNA segment of 1.3 kb harboring little more than the coding region of the dhaA gene. In strains 170 and GP1, a putative integrase gene was found next to the conserved dhaA segment, which suggests that integration events were responsible for the acquisition of these DNA segments. The data indicate that horizontal gene transfer and integrase-dependent gene acquisition were the key mechanisms for the evolution of catabolic pathways for the man-made chemicals 1, 3-dichloropropene and 1,2-dibromoethane.  (+info)

Ethanol and arachidonic acid increase alpha 2(I) collagen expression in rat hepatic stellate cells overexpressing cytochrome P450 2E1. Role of H2O2 and cyclooxygenase-2. (8/436)

The ability of ethanol and arachidonic acid (AA), as inducers of oxidative stress and key factors in alcoholic liver disease, to up-regulate alpha 2 collagen type I (COL1A2) gene expression was studied in a hepatic stellate cell line overexpressing the ethanol-inducible cytochrome P450 2E1 (CYP2E1) (E5 cells). A time- and dose-dependent induction in COL1A2 mRNA by ethanol or AA was observed that was prevented by diallylsulfide, a CYP2E1 inhibitor. Nuclear run-on experiments showed transcriptional activation of the COL1A2 gene by ethanol and AA. Catalase abrogated the increase in COL1A2 mRNA suggesting an H(2)O(2)-dependent mechanism. Cyclooxygenase-2 (COX-2) levels and production of prostaglandin E(2) upon addition of AA were elevated in the E5 cells. Incubation with NS-398, a COX-2 inhibitor, blocked the effect of AA, but not of ethanol, on COL1A2 expression suggesting that CYP2E1 activates COX-2 expression, and the oxidation of AA by COX-2 is responsible for the increase in COL1A2. Activity of a reporter construct driven by -378 base pairs of the proximal promoter region of the COL1A2 gene increased in E5 but not control cells and was further increased by ethanol or AA. These experiments link CYP2E1-dependent oxidative stress to induction of COX-2 and the actions of ethanol and AA on activation of collagen gene expression in hepatic stellate cells.  (+info)

*Sonogashira coupling

... compound F. Compound F continues to react with the palladium intermediate B, with regeneration of the copper halide, G. ... There are also examples of the coupling partners both being attached to allyl resins, with the Pd(0) catalyst effecting ... The active palladium catalyst is the 14 electron compound Pd0L2, complex A, which reacts with the aryl or vinyl halide in an ... In an inverse Sonogashira coupling the reactants are an aryl or vinyl compound and an alkynyl halide. While a copper co- ...

*White catalyst

This compound is commercially available. It may be prepared by oxidation of 1,2-bis(phenylthio)ethane to the sulfoxide, ... In order to promote nucleophilic attack at the internal terminus of the π-allyl to generate branched product, a tethered N- ... It has been shown that functionalization of the π-allyl intermediate may be promoted by chromium(III) salen chloride activation ... activating the π-allyl complex to nucleophilic attack (III). A nucleophile, in this case acetate, attacks to reductively ...

*Propenyl

... compounds are isomeric with and less common than allyl compounds. Propene Radical (chemistry) http://www.biology- ... Many propenyl compounds are known, such as cis- and trans-1-chloropropene, propenylbenzene (β-methylstyrene). ...

*Allyl acetate

... is an organic compound with formula C3H5OC(O)CH3. This colourless liquid is a precursor to especially allyl ... Allyl acetate can be hydrolyzed to allyl alcohol: CH2=CHCH2OCOCH3 + H2O → CH2=CHCH2OH + CH3COOH Allyl alcohol is a precursor ... Allyl alcohol is also produced primarily from allyl chloride, but production via the hydrolysis of allyl acetate route avoids ... 2000). "Allyl Compounds. Ullmann's Encyclopedia of Industrial Chemistry". Ullmann's Encyclopedia of Industrial Chemistry. doi: ...

*Allylic rearrangement

This is likely in cases when the allyl compound is unhindered, and a strong nucleophile is used. The products will be similar ... An allylic rearrangement or allylic shift is an organic reaction in which the double bond in an allyl chemical compound shifts ... Allyl shifts can also take place with electrophiles. In the example below the carbonyl group in benzaldehyde is activated by ... reduction a formal organic reduction on an allyl group containing a good leaving group is accompanied by a rearrangement. One ...

*Trimethylenemethane cycloaddition

5) Silylated allylic acetates, carbonates and other substituted allyl compounds may form TMM synthons under palladium catalysis ... Carbonyl compounds may be used as the 2π component under the appropriate conditions. For instance, in the presence of an indium ... Three classes of compounds have been used to generate synthetically useful TMM intermediates: diazenes, silyl-substituted ... Rapid racemization of chiral pi-allyl palladium complexes occurs, and only moderate diastereoselectivity is observed in ...

*1,3-Dichloropropene

Ludger Krähling, Jürgen Krey, Gerald Jakobson, Johann Grolig, Leopold Miksche "Allyl Compounds" in Ullmann's Encyclopedia of ... It is a byproduct in the chlorination of propene to make allyl chloride. It is usually obtained as a mixture of the geometric ... 1,3-Dichloropropene, sold under diverse trade names, is an organochlorine compound. It is colorless liquid with a sweet smell. ... Compound ATSDR Toxicological Profile (9.2 MB) CDC - NIOSH Pocket Guide to Chemical Hazards. ...

*Horseradish

Allyl isothiocyanate is an unstable compound, degrading over the course of days at 37 °C (99 °F). Because of this instability, ... The distinctive pungent taste of horseradish is from the compound allyl isothiocyanate. Upon crushing the flesh of horseradish ... The allyl isothiocyanate serves the plant as a natural defense against herbivores. Since allyl isothiocyanate is harmful to the ... When cut or grated enzymes from the now-broken plant cells break down sinigrin (a glucosinolate) to produce allyl ...

*Organopalladium

Allyl compounds with suitable leaving groups react with palladium(II) salts to pi-allyl complexes having hapticity 3 such as ... Palladium compounds owe their reactivity to the ease of interconversion between Pd(0) and palladium(II) intermediates. There is ... The first organopalladium(IV) compound was described in 1986. This complex is Me3Pd(IV)Ibpy with bpy as a bidentate 2,2'- ... Zerovalent Pd(0) compounds such as tris(dibenzylideneacetone)dipalladium(0) and tetrakis(triphenylphosphine)palladium(0) react ...

*Allyl alcohol

... s in general can be prepared by allylic oxidation of allyl compounds by selenium dioxide. Allyl alcohol is ... Allyl alcohol was first prepared in 1856 by Auguste Cahours and August Hofmann by saponification of allyl iodide. Today allyl ... Allyl alcohol (IUPAC name: prop-2-en-1-ol) is an organic compound with the structural formula CH2=CHCH2OH. Like many alcohols, ... Today allyl alcohol can be obtained by many methods. Allyl alcohol is the smallest representative of the allylic alcohols. ...

*Vinyl group

In allyl compounds, where the next carbon is saturated but substituted once, allylic rearrangement and related reactions are ... The name is also used for any compound containing that group, namely R−CH=CH2 where R is any other group of atoms. An ... Allyl Grignard reagents (organomagnesiums) can attack with the vinyl end first. If next to an electron-withdrawing group, ... Allyls, acrylates and styrenics contain vinyl groups. (A styrenic crosslinker with two vinyl groups is called divinyl benzene ...

*List of MeSH codes (D02)

... allyl compounds MeSH D02.455.326.271.122.100 --- allylamine MeSH D02.455.326.271.122.260 --- allylglycine MeSH D02.455.326.271. ... trialkyltin compounds MeSH D02.691.850.900.910 --- triethyltin compounds MeSH D02.691.850.900.950 --- trimethyltin compounds ... mustard compounds MeSH D02.455.526.728.468 --- mustard gas MeSH D02.455.526.728.650 --- nitrogen mustard compounds MeSH D02.455 ... bephenium compounds MeSH D02.092.877.096.333 --- bretylium compounds MeSH D02.092.877.096.333.150 --- bretylium tosylate MeSH ...

*Allyl phenyl ether

This position is actually necessary and can only be formed by certain compounds like allyl phenyl ether. One type of synthesis ... Allyl phenyl ether is a good starting reactant for many different experiments. One experiment that it is used for is the ... Allyl phenyl ether (C9H10O) is a clear and very slight yellow liquid that is stable under normal temperatures and pressures. ... Hsu-chin Hsiao, J. D.; Hung-shan Weng, J. D., ANALYSIS OF FACTORS AFFECTING THE SYNTHESIS OF ALLYL PHENYL ETHER BY TRI-LIQUID- ...

*Carbon

... η2-alkene compounds (for example, Zeise's salt), and η3-allyl compounds (for example, allylpalladium chloride dimer); ... Organometallic compounds by definition contain at least one carbon-metal bond. A wide range of such compounds exist; major ... Carbon forms a vast number of compounds, more than any other element, with almost ten million compounds described to date, and ... Carbon is known to form almost ten million different compounds, a large majority of all chemical compounds. Carbon also has the ...

*List of phytochemicals in food

... allium compounds) Allyl methyl trisulfide garlic, onions, leeks, chives, shallots. Sulfides Diallyl disulfide garlic, onions, ... Allyl isothiocyanate horseradish, mustard, wasabi. Piperine black pepper. Syn-propanethial-S-oxide cut onions. Betacyanins ... Allyl isothiocyanate Phenethyl Isothiocyanate Benzyl Isothiocyanate Oxazolidine-2-thiones Nitriles Thiocyanates Polysulfides ( ... Sinigrin (the precursor to allyl isothiocyanate) broccoli family, brussels sprouts, black mustard. Glucotropaeolin (the ...

*Perfume

For example, the compound Tricyclodecenyl allyl ether is often found in synthetic perfumes and has insect repellent property. ... Plants are by far the largest source of fragrant compounds used in perfumery. The sources of these compounds may be derived ... By using a slightly hydrophilic compound such as ethanol, most of the fragrant compounds from the waxy source materials can be ... aromatic compounds Esprit de Parfum (ESdP): 15-30% aromatic compounds, a seldom used strength concentration in between EdP and ...

*Diallyl disulfide

It decomposes in the human body into other compounds such as allyl methyl sulfide. In 1844, Theodor Wertheim separated by steam ... Allyl propyl disulfide allyl disulfide Diallyl disulfide at Sigma Aldrich Block, E (2010). Garlic and Other Alliums: The Lore ... diallyl disulfide is produced from sodium disulfide and allyl bromide or allyl chloride at temperatures of 40-60 °C in an inert ... Fukao, T; Hosono, T; Misawa, S; Seki, T; Ariga, T (2004). "The effects of allyl sulfides on the induction of phase II ...

*Garlic allergy

... together with related compounds allyl propyl disulfide and allicin. These chemicals occur in oils of plants of the genus Allium ...

*Garlic mustard as an invasive species

Garlic mustard produces allelochemicals, mainly in the form of the compounds allyl isothiocyanate and benzyl isothiocyanate, ... Garlic mustard produces a variety of secondary compounds including flavonoids, defense proteins, glycosides, and glucosinolates ...

*TRPV1

... the irritating compound in hot chili peppers; and allyl isothiocyanate, the pungent compound in mustard and wasabi. The ...

*Allylamine

Ludger Krähling; Jürgen Krey; Gerald Jakobson; Johann Grolig; Leopold Miksche (2002). "Allyl Compounds". Ullmann's Encyclopedia ... Allylamine, like other allyl derivatives is a lachrymator and skin irritant. Its oral LD50 is 106 mg/kg for rats. Nomenclature ... Pure samples can be prepared by hydrolysis of allyl isothiocyanate. It behaves as a typical amine. Polymerization can be used ... Allylamine is an organic compound with the formula C3H5NH2. This colorless liquid is the simplest stable unsaturated amine. All ...

*Trifluoroperacetic acid

In the case of an allyl alcohol compound with a proximate carbonyl functional group, the epoxide can undergo a ring-expansion ... and conversion of nitroso compounds to nitro compounds or nitramines. For example, a mixture of hydrogen peroxide and ... The hypervalent compound is accessible in two ways, and which is chosen usually depends on what materials are available: it can ... One example is the formation of the hypervalent iodine compound (bis(trifluoroacetoxy)iodo)benzene, (CF 3COO) 2IC 6H 5 which is ...

*Allyl hexanoate

... is an organic compound with the formula C5H11CO2CH2CH=CH2. It is colorless liquid, although commercial samples ... Allyl hexanoate at The Good Scents Company Allyl caproate at Sigma-Aldrich Johannes Panten and Horst Surburg "Flavors and ... Allyl hexanoate is employed principally in the formulation of pineapple flavors but it can also be used for peach and apricot ... Fragrances, 2. Aliphatic Compounds" in Ullmann's Encyclopedia of Industrial Chemistry, 2015, Wiley-VCH, Weinheim.doi:10.1002/ ...

*Organocobalt chemistry

Organocobalt compounds are known with alkene, allyl, diene, and Cp ligands. A famous sandwich compound is cobaltocene, a 19- ... Other sandwich compounds are CoCp(C6Me6) and Co(C6Me6)2, with 20 electrons and 21 electrons, respectively. Reduction of cobalt( ... Organocobalt compounds are involved in several organic reactions and the important biomolecule vitamin B12 has a cobalt-carbon ... Cobalt compounds react with dialkynes and dienes to cyclic intermediates in cyclometalation. Other alkynes, alkenes, nitriles ...

*Organostannane addition

Methods for the addition of allyl groups to carbonyl compounds are numerous and incorporate a variety of metals. Organochromium ... These compounds are usually prepared by enantioselective reduction with a chiral reducing agent such as BINAL-H. In the ... These compounds react similarly to allylstannanes, affording homopropargyl alcohols. Imines are less reactive than the ... Reactions should be carried out in a well-ventilated fume hood, however, as volatile organotin compounds are highly toxic. Gung ...

*PF-4840154

The compound is a potent, selective activator of both the human (EC50 = 23 nM) and rat (EC50 = 97 nM) TRPA1 channels. This ... and is superior to allyl isothiocyanate for this use. The TRPA1 channel is considered an attractive pain target based on the ... compound elicits nociception in a mouse model through TRPA1 activation. PF-4840154 is used as a reference agonist of the TRPA1 ...

*Organolithium reagent

In allyl lithium compounds, the lithium cation coordinates to the face of the carbon π bond in an η-3 fashion instead of a ... Metalation of allyl ether with alkyllithium or LDA forms an anion α to the oxygen, and can proceed to 2,3-Wittig rearrangement ... For aromatic compounds, the position of lithiation is also determined by the directing effect of substituent groups. Some of ... In heteroaromatic compounds, metalation usually occurs at the position ortho to the heteroatom. See lithium-halogen exchange ( ...
Diallyl trisulfide (DATS), also known as Allitridin, is an organosulfur compound with the formula S(SCH2CH=CH2)2. It is one of several produced by the hydrolysis of allicin, including diallyl disulfide and diallyl tetrasulfide, DATS is one of the most potent. Many health benefits of garlic are attributed in part to DATS. These benefits include anti-cancer effects, platelet aggregation, blood pressure reduction, decreases in cholesterol levels, and increases in levels of reactive oxygen species. DATS has been shown to selectively kill cancerous cells in the prostate and breast, leaving healthy cells unharmed. This effect is attributed to increased reactive oxygen species (ROS) within cancer cells, increased the number of cells that arrest in the G2 phase of mitosis, and promote an increase in caspase-3 activity. These effects appear to contribute to the apoptosis of cancer cells and a decrease in cancer cell proliferation. DATS can be metabolized by glutathione in red blood cells to form hydrogen ...
diallyl disulfide 2179-57-9 Precursor and Downstream products, diallyl disulfide Precursor products, diallyl disulfide Downstream products ect.
Diallyl sulfide (DAS), diallyl disulfide (DADS) and diallyl trisulfide (DATS) are major oil-soluble organosulfur compounds of garlic responsible for most of its pharmacological effects. The present study investigated the influence of repeated intraperitoneally (ip) administration of DAS, DADS and DATS on the total level of sulfane sulfur, bound sulfur (S-sulfhydration) and hydrogen sulfide (H2S) and on the activity of enzymes, which catalyze sulfane sulfur formation and transfer from a donor to an acceptor in the normal mouse kidney, i.e., γ-cystathionase (CSE) and rhodanese (TST). The activity of aldehyde dehydrogenase (ALDH), which is a redox-sensitive protein, containing an -SH group in its catalytic center, was also determined. The obtained results indicated that all tested compounds significantly increased the activity of TST. Moreover, DADS and DATS increased the total sulfane sulfur level and CSE activity in the normal mouse kidney. ALDH activity was inhibited in the kidney after DATS
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1574 Epidemiological data continues to support the notion that increased consumption of Allium vegetables may reduce the risk for different types of malignancies including cancer of the prostate. Moreover, allium vegetable derived organosulfur compounds, such as diallyl trisulfide (DATS; CH2=CH-CH2-(S)3-CH2-CH=CH2), are highly effective in affording protection against cancer development in animal models. Evidence is mounting to indicate that garlic-derived organosulfur compounds can suppress proliferation of cultured cancer cells by inhibiting cell cycle progression and causing apoptosis induction. Previous studies including those from our laboratory have offered novel insights into the mechanism of apoptosis induction by DATS. For instance we showed previously that DATS-induced apoptosis in PC-3 and DU145 human prostate cancer cells was associated with c-jun N-terminal kinase mediated phosphorylation of Bcl-2, which reduced Bax-Bcl-2 interaction to trigger activation of caspase-9/3. In the ...
US EPA PC Code ); 006901 (US EPA PC Code Text ); 12044-79-0 (CAS number); 12044790; 12044790 (CAS number without hyphens); 12344682; 12612214; 1303-33-9 (CAS number); 1303-34-0 (CAS number); 1303339; 1303339 (CAS number without hyphens); 1303340; 1303340 (CAS number without hyphens); 56320220; Arsenic disulfide (CAS 56320-22-0); Arsenic sesquisulfide; Arsenic sesquisulfide (CAS 1303-33-9); Arsenic sulphide; Arsenic trisulfide; Arsenic trisulfide (As2S3); Arsenic trisulfide (CAS 1303-33-9); Arsenic trisulphide; Arsenic yellow; Arsenic yellow (CAS 1303-33-9); Arsenictrisulfide; Arsenone S; Arsenone S (CAS 12344-68-2); Diarsenic pentasulfide; Diarsenic pentasulfide (CAS 1303-34-0); Diarsenic tetrasulfide; Diarsenic tetrasulfide (CAS 12344-68-2); Diarsenic trisulfide; Diarsenic trisulfide (CAS 1303-33-9); Thioxoarsino; Thioxoarsino (CAS 12044-79-0 ...
Naturally occurring compounds belonging to two chemical groups were studied for their capacities to inhibit N-nitrosodiethylamine (NDEA)-induced carcinogenesis in female A/J mice. One group consists of organosulfur compounds found in Allium species, including garlic, onions, leeks, and shallots, and the other, two monoterpenes, i.e., d-limonene and d-carvone. In an initial experiment, in which organosulfur compounds were investigated, diallyl disulfide, allyl mercaptan, and allyl methyl disulfide were found to produce a marked inhibition of NDEA-induced neoplasia of the forestomach when the test compounds were administered p.o. 96 and 48 h prior to NDEA. The most potent was diallyl disulfide which reduced forestomach tumor formation by more than 90%. Pulmonary adenoma formation also was inhibited but to a considerably lesser extent, i.e., about 30%. In three additional experiments, test compounds were given p.o. either 15 min or 1 h prior to NDEA. Under these conditions diallyl disulfide and ...
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Allylstannanes are relatively stable reagents in the allylmetal family, and have been employed in a variety of complex organic syntheses. In fact, allylstannane addition is one of the most common methods for producing polypropionates, polyacetates, and other oxygenated molecules with a contiguous arrays of stereocenters.[10] Ley and coworkers[11] used an allylstannane to allylate a threose-derived aldehyde (see figure) en route to the macrolide antascomicin B, which structurally resembles FK506 and rapamycin, and is a potent binder of FKBP12. Allylboration is also often used to add allyl groups in a 1,2 fashion to aldehydes and ketones. Thanks to decades of research, there is now a wide variety of organoboron reagents available to the synthetic chemist, including organoboranes that predictably yield products in high diastereo- and enantioselectivity.[12] If a one-pot metal insertion and allylation procedure is required, indium- mediated allylation is an attractive option for generating ...
A number of studies on garlic have appeared dealing with diallyl sulfide and cancer. One from the Republic of Korea cites diallyl disulfide (DADS) as the most prevalent oil-soluble sulfur compound in garlic, inhibiting cell proliferation in many cell lines. Scientists there examined DADS ability to kill cells in a process involving free radical production. They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present. Cancer cells died following 24 hour DADS treatment that activated the p53 gene. They also found that DADS induced cell death was prevented by treatment with a compound known to prevent p53 dependent cell death by reducing free radical levels in the mitochrondria, the cellular furnaces. Their results showed that mitochrondrial free radicals may serve as second messengers in DADS-induced cell death, which requires activation of p53. That study was found in the Journal of Biochemical and Molecular Toxicology ...
A number of studies on garlic have appeared dealing with diallyl sulfide and cancer. One from the Republic of Korea cites diallyl disulfide (DADS) as the most prevalent oil-soluble sulfur compound in garlic, inhibiting cell proliferation in many cell lines. Scientists there examined DADS ability to kill cells in a process involving free radical production. They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present. Cancer cells died following 24 hour DADS treatment that activated the p53 gene. They also found that DADS induced cell death was prevented by treatment with a compound known to prevent p53 dependent cell death by reducing free radical levels in the mitochrondria, the cellular furnaces. Their results showed that mitochrondrial free radicals may serve as second messengers in DADS-induced cell death, which requires activation of p53. That study was found in the Journal of Biochemical and Molecular Toxicology ...
... definition, a colorless, volatile, flammable liquid, C 3 H 5 Cl, having a pungent odor, derived from propylene by chlorination: used chiefly in the synthesis of allyl alcohol, resins, and pharmaceuticals. See more.
AIM: To investigate the mechanism of allitridi-induced apoptosis in human gastric cancer cell line BGC823. METHODS: Growth inhibition by allitridi was analyzed using cell growth curve and MTT assay. Apoptotic cells were detected using staining with Hoechst 33342, and confirmed by flow cytometric analysis and DNA fragmentation analysis. The protein expression affected by allitridi was determined using Western blot. The activity of caspase-3 was measured using a fluorescence assay. RESULTS: Allitridi induced apoptosis, and then inhibited cells proliferation in human gastric cancer cell line BGC823. The protein level of Bcl-2 was decreased dramatically, while Bax and p53 were not significantly affected by allitridi. The expression and activity of caspase-3 started to increase after allitridi treatment for 72 h. CONCLUSION: Allitridi induced apoptosis through down-regulation of Bcl-2, and increased caspase-3 expression and its activity. ...
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Arsenic trisulfide definition, a yellow or red crystalline substance, As 2 S 3 , occurring in nature as the mineral orpiment, and used as a pigment (kings yellow) and in pyrotechnics. See more.
Sulfur represents approximately 1/4% of our total body weight and occurs principally in the body as a constituent of the cysteine and methionine. It plays an important role in protein synthesis and enzyme reaction functions and is found abundantly in broccoli, cauliflower, cabbage, kale, kohlrabi, etc. Organosulfides Organosulfur compounds presented in natural food are generally …. ...
Diallyl sulfide (DAS) and diallyl disulfide (DADS) are natural components that could account for the anticarcinogenic properties of garlic, at least in part, through the activation of xenobiotic detoxifying metabolism. The aim of this work was to describe the effect of DAS and DADS on xenobiotic-related gene expressions and to study molecular mechanisms relaying DAS effect. We describe the different effects of DAS and DADS on hepatic CYP2B1/2, CYP3A and epoxide hydrolase (EpH) mRNAs in rats, in terms of activation profile, doses and kinetics. The activation profile varied with the mode of chemical administration, i.e. gastric infusion or intraperitoneal (i.p.) injection. Using gastric infusion, DAS and DADS proved different efficiencies at enhancing the mRNA level of the three drug-metabolizing enzymes. After an i.p. administration, we observed a specific activation of CYP2B1/2 gene by DAS. The DAS-mediated CYP2B1/2 activation occurred at transcriptional level and through an okadaic ...
Allyl sulfide is a chemical compound with the formula C6H10S and a molecular weight of 114.21 g/mol. It is a clear, colorless liquid with a garlic odour and...
AR plays an important role in the development of prostate cancer as well as in the transition to castration-resistant state, which is highly aggressive and resistant to chemotherapy (4, 38). Thus, the preclinical/clinical development of novel agents that are safe but can suppress AR signaling is highly desirable. The present study shows that DATS treatment suppresses protein level of AR in both LNCaP cells and their androgen-independent variant. The DATS-mediated AR protein down-regulation is maintained for at least up to 24 hours even after removal of the drug. In addition, DATS treatment exhibits significant antiproliferative effect against androgen-stimulated growth of LNCaP cells.. We also conclude that the DATS-mediated suppression of AR protein level leads to inhibition of transcriptional activity of AR as evidenced by a significant decrease in secreted as well as intracellular levels of PSA in both LNCaP and C4-2 cells. Structure-activity analysis reveals that even a subtle change in the ...
Butyl methyl trisulfide | C5H12S3 | CID 189722 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Said compositions is also useful for reducing skin redness, detaining the formation of new acne outbreaks, reversing already existing outbreaks and regenerating skin damage caused by acne.
Sigma-Aldrich offers abstracts and full-text articles by [Fenja Klevenhusena, Stephane Duval, Johanna O Zeitz, Michael Kreuzer, Carla R Soliva].
The report generally describes allyl acetate, examines its uses, production methods, patents. Allyl acetate market situation is overviewed; allyl acetate
178366-78-4 - 6,8-Diallyl 5,7-dihydroxy 2-(2-allyl 3-hydroxy 4-methoxyphenyl)1-H benzo(b)pyran-4-one - Searchable synonyms, formulas, resource links, and other chemical information.
Facile formation of allylzinc species from allylboronate and zinc amide was discovered. The boron-to-zinc exchange process occurred smoothly to afford the corresponding allylzinc amides, which were successfully employed in catalytic allylation reactions with electrophiles. Asymmetric catalysis using a chiral
A topical formulation includes a water-soluble ingredient and an oil-soluble ingredient and includes a combination of water, a rheology modifier, and a water miscible organic solvent to stabilize the composition.
ALLYL BROMIDE | C3H5Br | CID 7841 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
J Am Acad Dermatol. 1990 Feb;22(2 Pt 1):231-8. Review.. Inhibition of benzoyl peroxide-mediated tumor promotion in 7,12-dimethylbenz(a)anthracene-initiated skin of Sencar mice by antioxidants nordihydroguaiaretic acid and diallyl sulfide ...
DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed.. DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. To view updated drug label links, paste the RSS feed address (URL) shown below into a RSS reader, or use a browser which supports RSS feeds, such as Safari for Mac OS X.. ...
Diallyl N,N-diisopropylphosphoramidite/AFI126429218 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
A crosslinking agent containing a polyallyl ether compound having at least one hydroxyl group derived from a glycidyl group and at least two allyl groups can be used for the production of a highly water-absorbing polymer comprising a polymerizable compound having a carbon-carbon double bond or a salt thereof, has a high solubility in aqueous solution of the monomer and gives a highly water-absorbing polymer having water absorptivity required at practical levels.
Looking for Disulphide? Find out information about Disulphide. A compound that has two sulfur atoms bonded to a radical or element. One of a group of organosulfur compounds RSSR′ that may be symmetrical or unsymmetrical Explanation of Disulphide
The 68845NV basic set includes 12 carbons, 18 hydrogens & 1 2 hole sulfur atom sufficient to build at least one basic organosulfur compound.
[150 Pages Report] Check for Discount on 2016 Natural Allyl Heptylate (CAS 142-19-8) Industry Market Report report by Prof Research. The Global and Chinese Natural Allyl Heptylate Industry, 2011-2021...
Im Greg, an autistic dad self-diagnosed at age 31. I have twin three year olds, one of whom is autistic. Im new to the autism community only in the sense that my son introduced my partner Meg and I…
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
Rob Van Driel is the Daddy on a mission after the early arrival of his daughter, Charlie, at 31 weeks gestation in June last year. Charlie was six weeks old
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allyl 2-methyl-2-phenylhydrazinecarboxylate - chemical structural formula, chemical names, chemical properties, synthesis references
|p |Silia|em||span style=color: #f37021;|Bond|/span||/em||sup|® |/sup|Allyl (Si-Allyl) can be used as solid support for further derivatization.|/p| |p||a href={{media url=specsheets/spec-R53530B.pdf}} target=_blank|PRODUCT SPECIFICATIONS|
Additives China, Sodium Allyl Sulfonate, Useage: 1)As the third monomer of acrylic, this produt can improve the dying properities, the heat resistance and flexib...
While our attitudes toward stay-at-home dads have evolved over the years, there are still some people who are shocked to see a man care for his children.
The Archnemesis Dad trope as used in popular culture. Some fathers just really dont do well by their kids, at all. Some are aloof, remote, and offer scant …
Consider pressure-volume loops for heart failure with preserved ejection fraction (HFpEF) diagnosis. PV loops directly demonstrate that patients with HFpEF have an abnormality of passive diastolic properties by measuring their EDPVR.
Garlic is a powerful cancer blocker. A number of the new studies on garlic that have recently appeared deal with garlic and cancer. One from the Republic of Korea cites diallyl disulfide (DADS) as the most prevalent oil-soluble sulfur compound in garlic, inhibiting cell proliferation in many cell lines. Scientists there examined DADS ability to kill cells in a process involving free radical production. They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present. Cancer cells died following 24 hour DADS treatment that activated the p53 gene. They also found that DADS induced cell death was prevented by treatment with a compound known to prevent p53 dependent cell death by reducing free radical levels in the mitochrondria, the cellular furnaces. Their results showed that mitochrondrial free radicals may serve as second messengers in DADS-induced cell death, which requires activation of p53. This study can be found in the January Journal of ...
A number of the new studies on garlic that have recently appeared deal with garlic and cancer. One from the Republic of Korea cites diallyl disulfide (DADS) as the most prevalent oil-soluble sulfur compound in garlic, inhibiting cell proliferation in many cell lines. Scientists there examined DADS ability to kill cells in a process involving free radical production. They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present. Cancer cells died following 24 hour DADS treatment that activated the p53 gene. They also found that DADS induced cell death was prevented by treatment with a compound known to prevent p53 dependent cell death by reducing free radical levels in the mitochrondria, the cellular furnaces. Their results showed that mitochrondrial free radicals may serve as second messengers in DADS-induced cell death, which requires activation of p53. This study can be found in the January Journal of Biochemical and Molecular Toxicology ...
garlic, glioblastoma, MUSC, neuro-oncology, The Medical University of South Carolina, Dr. Arabinda Das, DATS, diallyl trisulfide, brain tumor
A novel method for producing a diallyl ester of an aromatic dicarboxylic acid, particularly a diallyl ester of an aromatic symmetrical dicarboxylic acid by ester-exchange of a dialkyl ester of the aromatic dicarboxylic acid with allyl alcohol in the co-presence of two kinds of catalysts is disclosed.The obtained diallyl ester of an aromatic dicarboxylic acid according to the present invention is excellent in transmissivity.
This thesis deals with secondary interactions in asymmetric catalysis and their impact on the outcome of catalytic reactions.. The first part revolves around the metal-catalyzed asymmetric allylic alkylation reaction and how interactions within the catalyst affect the stereochemistry. An OH-Pd hydrogen bond in Pd(0)-π-olefin complexes of hydroxy-containing oxazoline ligands was identified by density functional theory computations and helped to rationalize the contrasting results obtained employing hydroxy- and methoxy-containing ligands in the catalytic reaction. This type of hydrogen bond was further studied in phenanthroline metal complexes. As expected for a hydrogen bond, the strength of the bond was found to increase with increased electron density at the metal and with increased acidity of the hydroxy protons.. The second part deals with the use of hydroxy- and methoxy-containing phosphinooxazoline ligands in the rhodium- and iridium-catalyzed asymmetric hydrosilylation reaction. The ...
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Extracts of fresh garlic, or Allium sativum, that are aged over a prolonged period contain antioxidant phytochemicals that fight against oxidant damage. These antioxidant phytochemicals include unique water-soluble organosulfur compounds, lipid-soluble organosulfur components and flavonoids, notably allixin and selenium. Longterm extraction of garlic (up to 20 months) ages the extract, retaining garlic nutrients while creating antioxidant properties by modifying unstable molecules with antioxidant activity, such as allicin. This aging process also increases stable and highly bioavailable organosulfur compounds, such as Sallylcysteine and S allylmercaptocysteine more antioxidant phytochemicals. And the aging process results in a truly odorless supplement. As a result, in addition to offering heart, brain, colon and other health benefits, AGE works as a powerful antioxidant, age-defying supplement by scavenging those pesky ROS, enhancing certain cellular antioxidant enzymes and increasing ...
An antioxidant lubricant composition has at least 50 wt % of a lubricating base oil and an oil-soluble metal compound providing between 1 and 2,000 parts per million of metal to the lubricant composition, the metal compound being chosen from the group consisting of molybdenum, tungsten titanium and boron compounds, and an oil-soluble hindered amine providing between about 0.001 and about 2 wt % of oil-soluble hindered amine to the lubricant composition, and optionally, an oil-soluble diarylamine providing between 0.001 and about 2 wt % of oil-soluble diarylamine to the lubricant composition.
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The green onion is an unassuming little vegetable. Its generally content to hang around in the background of many dishes, including much of what you find at our Seattle Korean restaurant, rarely ever drawing notice to itself. In case youve ever paid them any thought, though, its worth noting the many health benefits that the green onion offers.. A typical vegetable, the green onion is low in calories and features no fat or cholesterol. A single stalk of the plant offers ten percent of your recommended daily intake of vitamin A, nine percent of your vitamin C, and a touch of calcium and iron.. Green onions also contain organosulfur compounds. These compounds are good for preventing the decline of your cartilage as you age. A diet rich on organosulfur compounds can therefore help you avoid osteoarthritis, a painful condition associated with the atrophy of cartilage in the joints.. Quercetin, a valuable flavonoid found in green onions, is a valuable part of a healthy body. Not only does it ...
... is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in horseradish, mustard, wasabi, etc. Health Benefits 1. Brain Cancer In the investigation of that AITC significantly decreased proliferation and viability of human brain malignant glioma GBM 8401 cells in a dose-dependent manner with IC50 9.25+/-0.69 microM for 24 h-treatment, showed …. ...
Jun 16, 2010 . The volatile oils in garlic (which have the antiseptic action) . We rub the garlic oil around the ear, especially underneath the ear and jaw moving down into the throat. . Intestinal parasites; Lice, skin parasites . They ranged in size from your average pencil eraser size down to smaller than a pin head ...
To explore the underlying mechanisms for the protective effects of garlic oil (GO) against nitrosodiethylamine (NDEA)-induced hepatocarcinoma, 60 male Wistar rats were randomized into 4 groups (...
I was at the LFS and they had a teeny tiny bottle of garlic oil for 15.95. I make my own herbal oils and I was wondering if there would be anything wrong in making my own. The oil consists of pressed
HABA GARLIC OIL GOLD | CV. AL AFIAT SEHAT ALAMI. Diskon > 50%. Info obat herbal lainya, hubungi toko herbal online kami. Melayani grosir herbal dan retail.
1. ABDA-Datenbank: Allium sativum monograph. WuV, Eschborn and Micromedex Inc, Englewood, CO; 1997. 2. Agarwal KC: Therapeutic actions of garlic constituents. Med Res Rev 1996; 16:111-124. 3. Apitz-Castro R, Escalante J, Vargas R et al: Ajoene, the antiplatelet principle of garlic, synergistically potentiates the antiaggregatory action of prostacyclin, forskolin, indomethacin, and dypiridamole on human platelets. Thromb Res 1986; 42:303-311. 4. Berthold HK, Sudhop T & von Bergmann K: Effect of a garlic oil preparation on serum lipoproteins and cholesterol metabolism. A randomized controlled trial. J Am Med Assoc 1998; 279:1900-1902. 5. Burnham BE: Garlic as a possible risk for postoperative bleeding (letter). Plast Reconstr Surg 1995; 95(1):213. 6. Canduela V, Mongil I, Carrascosa M et al: Garlic: always good for the health (letter)? Br J Dermatol 1995; 132(1):161-162. 7. Couturier P & Bousquet J: Occupational allergy secondary to inhalation of garlic dust (letter). J Allergy Clin Immunol 1983; ...
Garlic contains diallyl disulfide, which prevents enzymes from damaging cartilage. The allicin in garlic also reduces pain in people who have chronic and excessive inflammation. Opt for fresh garlic because may garlic powders contain preservatives that decrease the positive effects [12].. Although there is no cure for arthritis, certain foods have been shown to fight inflammation, strengthen bones and boost the immune system. Add these foods to your diet to help keep your arthritis pain at bay.. ...
Nominated Substances: Allyl bromide. Nomination Date: 07/05/1995 Nominator: NCI Rationale: Widespread use leading to human exposure associated with its manufacture and use; persistence as an environmental pollutant; a suspicion of carcinogenicity; alkylating agent; positive genotoxicity test results. NTP Principles: 2, 3, 6, 7. Status: Selected ...
Listing your company for Allyl Bromide allows buyers to find your information through our directory pages which appear in the top positions when a search is conducted in Google, Yahoo!, MSN etc ...
Amino acids in garlic reduce the "bad" cholesterol (LDL) and triglycerides, and increase the concentration of "good" cholesterol (HDL), even in the case of consumption of very fatty foods. It helps in the treatment of various diseases of the lungs, and is extremely effective in the treatment of influenza and chronic bronchitis.. It strengthens the immune system and makes the body resistant to viruses and infections of any type. It is effective in the case of headaches, painful cramping in the calves, common herpes on the body, Candida and other types of fungal infections.. It reduces blood pressure for amazing 5% to 10%.. The garlic oil is necessary for the treatment of diabetes due to its hypoglycemic properties. Scientists have proven that the regular consumption of garlic oil reduces the risk of cancer and slows the development of tumor cells in the body.. Garlic oil boosts the immune system and it is a strong fighter against respiratory infections, it facilitates breathing and coughing. In ...
Acetaminophen (APAP) when administered in excess can cause severe hepatic necrosis in vivo. To study the mechanism of APAP toxicity and the role of cytochrome P450, a previously established human hepatoma HepG2 subline, MVh2E1-9, that constitutively expresses human CYP2E1 was used as a model. At high concentrations (above 5 mM) and when intracellular reduced glutathione (GSH) was depleted, APAP caused severe cytotoxicity in MVh2E1-9, but not in MV-5 cells which lack CYP2E1. The APAP cytotoxicity was dependent on the concentration of APAP and time of exposure, and could be blocked by 4-methylpyrazole, ethanol, diallyl sulfide, N-acetylcysteine and N-t-butyl-alpha-phenylnitrone, but not by propylgallate, an inhibitor of lipid peroxidation. Significantly more 14C-labeled APAP protein adduct was detected in MVh2E1-9 cells than MV-5 cells, especially after depletion of GSH. The formation of the APAP adducts could be inhibited by the same agents which prevent APAP cytotoxicity. At a lower ...
Propylene Dichloride (PDC) is a byproduct of several Dow processes. The thermal cracking of PDC produces l - cis-chloropropene , I - trans-chloropropene, 2- chloropropene , and allyl chloride . By oxidizing the 1 - and 2-chloropropenes to 3- and 2 ...
A simple procedure for N-Allylation of allyl Acetates has been developed using a biodegradable and easily recyclable heterogeneous chitosan-supported palladium catalyst. The general methodology, applicable to wide range of substrates, has sustainable features that include a ligand-free reaction with simple workup, recycling and reusability of the catalyst.. ...
Lookup HS Codes for China vi 28.13.90 Other non-metallic sulfides, phosphorus trisulfide Goods. Avalara LandedCosts helps determine your duty rates and other import taxes for China.
Title: Meta-Analysis of Anticancer Drug Structures - Significance of Their Polar Allylic Moieties. VOLUME: 7 ISSUE: 2. Author(s):Norman S. Radin. Affiliation:10150 Torre Ave., Apt. 115,Cupertino, CA 95014-2129, USA.. Keywords:Allylic anticancer drugs, thiol condensations, ceramide in cancer therapy, reactive oxygen species, ubiquinone interference, sphingolipids as coenzymes. Abstract: This meta-analysis examines a wide range of small molecule anticancer drugs to search for a structure common to all. Although they encompass a very wide range of structures, nearly all reveal the presence of an allylic O, N, or S atom. In some, the allylic oxygen is a carbonyl group, or an alcohol group, which can be substituted (ester, lactone, glycoside, ether) or replaced by an amino or imino nitrogen Some antineoplastic drugs do not exhibit this moiety but are converted in vivo to allylic derivatives. An allylic hydroxyl is also present in most sphingolipids, ubiquitous body components that control ...
The test agent in this study is a product of biphenylmethyl dicarboxylate (BDD) with garlic oil. The two components were confirmed to have complementary effects because of different operational mechanism in animal experiments, and were examined on humans in this study. Both BDD and garlic oil are expected to show better protection and treatment on hepatotoxicity caused by toxic substances, and the purpose of this study is to confirm efficacy of and safety on human body of the agent and to determine its optimal dose ...
- It helps with blood circulation -100% natural Preventive against fungi, bacteria and viruses - Rich in vitamins - With a high content of polyunsaturated fatty acids
From the kitchen of One Perfect Bite...Ive been trying to test a series of skillet suppers for quick and easy weeknight meals. It has been slow going because Ive overbooked my calendar, but I am slogging my way through the pile of recipes with the intent of of sharing the best of them with you. Hopefully, that will be before school starts. Tonights recipe is one of a series that I found in a BuzzFeed article that featured stovetop chicken dishes. The recipe is a keeper and I think all but the youngest members of your family will enjoy it. Feel free to substitute thigh meat for the breast meat specified in the recipe and use any type of pasta that you enjoy. I hope you will give this recipe a try. You can have this dish on the table in 30 minutes and it makes a lovely supper. Here is the recipe. ...
A model two-step synthesis of a saturated hyperbranched hydroxyl-terminated ester has been developed to show a synthesis route. Three different series of hyperbranched esters with different terminations have been synthesized to relate some of their properties to their structures. This route has then been used to synthesize three different allyl ether-maleate functional hyperbranched ester resins in a two-step procedure. The resins have been characterized with respect to rheology, structure, and properties, and the differences are discussed. The allyl ether-maleate functional resins have also been studied with respect to curing performance and final film properties.. ...
And like conventional antibiotics and anti-virals, youll have to take garlic for a minimum of one week or youll run the risk of having a relapse. I made that mistake when I used the same treatment for a viral infection. I was so convinced of the power of my garlic-honey-lime remedy that I used it to treat the swollen, painful lymph nodes that my kids developed. Because they also were running a high fever, indicative of a full-blown infection, I increased the dose to one clove/tsp. every three hours. Each time, I also smothered garlic oil on their necks below the ears where the nodes were sore, and on the soles of their feet twice a day as a trans-dermal therapy. The treatment was effective, but once the symptoms improved, I brought the dose down immediately to three times per day or every eight hours. The kids suffered a rebound. For a systemic, high-grade infection like that, I would recommend administering a dose six to eight times a day. Increase the time between doses by an hour as soon as ...
NTP Experiment-Test: 96003-05 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01 Route: GAVAGE Time: 13:49:05 FINAL#1/MICE Facility: BIORELIANCE Chemical CAS #: 106-95-6 Lock Date: 10/18/00 Cage Range: All Reasons For Removal: All Removal Date Range: All Treatment Groups: Include All a Number of animals examined microscopically at site and number of animals with lesion Page 1 NTP Experiment-Test: 96003-05 INCIDENCE RATES OF NONNEOPLASTIC LESIONS BY ANATOMIC SITE (a) Report: PEIRPT03 Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01 Route: GAVAGE Time: 13:49:05 ____________________________________________________________________________________________________________________________________ MICE:P53+/-(C57BL/6) FEMALE VEHICLE 0.5 1 MG/KG 2 MG/KG 4 MG/KG 8 MG/KG CONTROL MG/KG ____________________________________________________________________________________________________________________________________ DISPOSITION ...
주의 설명서: P210-P301+P310a-P303+P361+P353-P305+P351+P338-P405-P501a Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations. ...
The product is the vinyl ether /allyl cationic/free-radical mixed curing monomer synthesized with diisocyanate of IPDI, with low toxicity, fast curing speed, curing thoroughly, low oxygen interference, little shrinkage, good strength of the cured coating and good toughness of the cured coating ...
Allyl benzoate/ACM583040 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
Creative Peptides offers H-Tyr(tBu)-allyl ester · HCl for your research. We also provide custom peptide synthesis, process development, GMP manufacturing.
Additives China, Manufacture Of Sodium Allyl Sulfonate Sas, 1)As the third monomer of acrylic fiber, this product can improve the dying properties, the heat resistance and flexibil...
[65 Pages Report] Check for Discount on fmoc-L-glutamic acid 5-allyl ester Global Market and Forecast Research report by ChemReport. DescriptionWe provide independent and unbiased information on manufacturers, prices, production...
Kemira Specialty, Inc., Northvale, NJ, has created Kemira NanoGel, an ingredient that produces a nanoemulsion at room temperature using only a blade propeller or even a spatula. When it is added at three times the amount of any oil or oil-soluble ing
GamADEKs CF Liquid is a multivitamin and multimineral supplement indicated for the dietary management of those patients having problems to absorb oil-soluble vitamins (A, D, E, and K) and other micronutrients from the GI tract, as may occur in cystic fibrosis and other malabsorption medical conditions. GamADEKs CF Liquid is an orange flavored non-oily liquid, containing no EDTA, BHA, BHT or artificial colors.. ...
Coenzyme Q10 is a substance found in the cells of the human body, necessary for cellular respiration and the production of energy. Co Q10 is an oil-soluble quinone, also called ubiquinone (which means
Coenzyme Q10 (CoQ10) is an oil-soluble, vitamin-like substance that is present in most living cells, and its job is to generate up to 95% of the bodys energy.
Hi, Please can you help me... I have a 3 year old daughter- her father and I split up about 4 months ago, when she sleeps, she cries for her dad, she asks me to call her dad so she can say hello, she cries before she sleeps for her dad. And this morning she said she wants to go stay by her dad?? She sees her dad on a Wed, and every second weekend (but doesnt sleep over). Please can you help me to help her as well as me feel at ease... What am I doing wrong?. ...
How to Roast Garlic. Aside from various health benefits, garlic tastes delicious. Roasted garlic is a particularly tasty and sweet, more mellow way to prepare and eat garlic. Roasted garlic can be added to a meal or eaten as a snack but...
David DeLuise, Actor: Megas XLR. The youngest son of legendary actor and comedian Dom DeLuise, David DeLuise is now perhaps the most popular dad on TV. Hes won the admiration of millions of children and parents alike for his portrayal of family patriarch Jerry on the hit Emmy award-winning Disney Channel series, Wizards of Waverly Place. He also starred in Wizards of Waverly Place: The Movie, which aired on the Disney ...
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
. 0 onjugated Systems hapter 0 onjugation in Alkadienes and Allylic Systems onjugated systems are those in which a π-bond is connected or conjugated (from the Latin conjugare which means to link r yoke
Power of Garlic, Garlic is well known for its ability to lower blood pressure (19) as well as reduce the oxidative stress inherent in those
Garlic is a popular ingredient in a great many foods, but do you know that garlic is an amazing tonic for your body and has the following benefits
This page is a non-solicitous resource, containing scientific abstracts and articles about the properties and health benefits of Garlic UPDATED 10-15-2017 http://www.chiro.org/nutrition/garlic.shtml
Garlic is one of those controversial supplements I like to talk about. Anything considered natural seems to have controversy linked to it. Like anything, garlic has its positives and its negatives. Making a choice for your horse is about knowing ...
The Ireland-Claisen rearrangement is the central step in the synthesis of tubuphenylalanine, a key building block of the highly antitumor-active tubulysins. The rearrangement of substituted β-amino acid allyl esters, in combination with subsequent d
Cas number 2489-86-3 Cas 2489-86-3 Cas #2489-86-3 Chemicals Chemicals 3-A-Naphthylpropene, 1-prop-2-Enylnaphthalene, 1-Allylnaphthalene, Allyl Naphthalene, Allylnaphthalene
The clip putting dad to bed Part 2 from Dad (1989) Well, shes getting what she needs. A good rest. Shell be home soon. Good night. Good night. Leave the hall light on. I will. Sleep well.
You need to be careful while consuming garlic especially if you are suffering from health conditions like bleeding disorder, stomach problems etc.
Garlic (Allium sativum L.) has been used for culinary and medicinal purposes by many cultures for centuries (1). Garlic is a particularly rich source of organosulfur compounds, which are thought to be responsible for its flavor and aroma, as well as its potential health benefits (2). Consumer interest in the health benefits of garlic is strong enough to place it among the best-selling herbal supplements in the United States (3). Scientists are interested in the potential for organosulfur compounds derived from garlic to prevent and treat chronic diseases, such as cancer and cardiovascular disease.. Summary. * Garlic (Allium sativum L.) is a particularly rich source of organosulfur compounds, which are currently under investigation for their potential to prevent and treat disease. * Crushing or chopping garlic releases an enzyme called alliinase that catalyzes the formation of allicin. Allicin rapidly breaks down to form a variety of organosulfur compounds. * Since cooking can inactivate ...
0091]The composition of the first or second mantle layer (22 or 40) may also contain an organosulfur compound or a metal salt thereof in addition to the base rubber and the unsaturated carboxylic acid metal salt, such as those disclosed in copending U.S. patent application Ser. No. 09/951,963 (now U.S. Pat. No. 6,635,716), the entirety of which is incorporated herein by reference. The addition of such organosulfur compounds to base rubber compositions exhibit increased COR, decreased compression, or both. The organosulfur compound or metal salt thereof is preferably a halogenated organosulfur compound, and more preferably a halogenated thiophenol, including, but not limited to, pentafluorothiophenol; 2-fluorothiophenol; 3-fluorothiophenol; 4-fluorothiophenol; 2,3-fluorothiophenol; 2,4-fluorothiophenol; 3,4-fluorothiophenol; 3,5-fluorothiophenol 2,3,4-fluorothiophenol; 3,4,5-fluorothiophenol; 2,3,4,5-tetrafluorothiophenol; 2,3,5,6-tetrafluorothiophenol; 4-chlorotetrafluorothiophenol; ...
monomers include, without limitation, polyalkyenyl ethers of sucrose or others polyols; diallyl phthalates; divinyl benzene; allyl (meth)acrylate, trimethylolpropane tri(meth)acrylate, diallyl itaconate, diallyl fumarate, diallyl maleate, hexanediol di(meth)acrylate, butanediol di(meth)acrylate, neopentyl glycol di(meth)acrylate, pentaerythritol tetra(meth)acrylate, dipentaerythritol penta(meth)acrylate, dipentaerythritol hexa(meth)acrylate, alkylene glycol di(meth)acrylates and polyalkylene gxycol di(meth)acrylates, such as ethylene glycol di(meth)acrylate, butylene glycol di(meth)acrylate, diethylene glycol di(meth)acrylate, triethylene glycol di(meth)acrylate, and polyethylene glycol di(meth)acrylate; diallyl terephthalate, and so on, as well as combinations of such monomers. A variety of pairs of mutually reactive groups are possible. Illustrative examples of such pairs of reactive groups include, without limitation, epoxide and carboxyl groups, amine and carboxyl groups, epoxide and amine ...
This thesis is focused on two main areas of organic synthesis, palladium-catalyzed functionalization of alkenes and allylic alcohols, as well as development of new allylboration reactions.. We have developed a palladium-catalyzed selective allylic trifluoroacetoxylation reaction based on C−H functionalization. Allylic trifluoroacetates were synthesized from functionalized olefins under oxidative conditions. The reactions proceed under mild conditions with a high level of diastereoselectivity. Mechanistic studies of the allylic C−H trifluoroacetoxylation indicate that the reaction proceeds via (η3-allyl)palladium(IV) intermediate.. Palladium-catalyzed regio- and stereoselective synthesis of allylboronic acids from allylic alcohols has been demonstrated. Diboronic acid B2(OH)4 was used as the boron source in this process.. The reactivity of the allylboronic acids were studied in three types of allylboration reactions: allylboration of ketones, imines and acyl hydrazones. All three processes ...
Acetone, Acrylonitrile, Allyl Chloride, Benzene, Bromobenzene, Bromochloromethane, Bromodichloromethane, Bromoform, Bromomethane, 2-Butanone (MEK), n-Butylbenzene, sec-Butylbenzene, tert-Butylbenzene, Carbon Disulfide, Carbon Tetrachloride, Chlorobenzene, Chlorodibromomethane, Chloroethane, Chloroform, Chloromethane, Chloroprene, 2-Chlorotoluene, 4-Chlorotoluene, 1,2-Dibromo-3-chloropropane, 1,2-Dibromoethane, Dibromomethane, 1,2-Dichlorobenzene, 1,3-Dichlorobenzene, 1,4-Dichlorobenzene, Dichlorodifluoromethane, 1,1-Dichloroethane, 1,2-Dichloroethane, 1,1-Dichloroethene, cis-1,2-Dichloroethene, trans-1,2-Dichloroethene, 1,2-Dichloropropane, 1,3-Dichloropropane, 2,2-Dichloropropane, 1,1-Dichloropropene, cis-1,3-Dichloropropene, trans-1,3-Dichloropropene, cis-1.4-Dichloro-2-butene, Ethylbenzene, Ethyl Ether, Hexachlorobutadiene, 2-Hexanone (MBK), Idomethane, Isopropylbenzene, p-Isopropyltoluene, Methylene Chloride, Methyl Methacrylate, Ethyl Methacrylate, Naphthalene, 4-methyl-2-Pentanone, ...
TABLE-US-00008 [0158]TABLE 1 Component 1 Class Component 2 Class Component 3 Class Nerolidol T Octyl glucoside C/CD Salicylic acid Se Piperine A/AD Chitosan C/CD KH2PO2 Se Nerolidol T Allyl isothiocyanate OI HEDP Se Allyl isothiocyanate OI N,N-bis(3- A/AD Salicylic acid Se aminopropyl)dodecylamine Nerolidol T N,N-bis(3- A/AD Salicylic acid Se aminopropyl)dodecylamine Nisin A/AD Allyl isothiocyanate OI HEDP Se Nisin A/AD Piperine A/AD 8-hydroxyquinoline Se Nerolidol T Methylene blue A/AD HEDP Se Allyl isothiocyanate OI Na pyrithione A/AD 2-hydroxypropyl-a- Se cyclodextrin Limonene T Na pyrithione A/AD Salicylic acid Se Piperine A/AD Allyl isothiocyanate OI Salicylic acid Se Piperine A/AD Limonene T 8-hydroxyquinoline Se N,N-bis(3- A/AD Naphthalene sulphonic acid Su KH2PO2 Se aminopropyl)dodecylamine Nerolidol T Usnic Acid DD 2-hydroxypropyl-a- Se cyclodextrin Allyl isothiocyanate OI Methylene blue A/AD KH2PO2 Se Glycerol Monocaprylate C/CD Allyl isothiocyanate OI Salicylic acid Se Usnic Acid DD ...
Williams LR, Home VN, et al. The composition and bactericidal activity of oil of Melaleuca alternifolia (Tea tree oil). Int J Aromather. 1989;1:15-17 May J, Chan CH, King A, et al. Time-kill studies of tea tree oils on clinical isolates. J Antimicrob Chemother. 2000;45:639-643. Tong MM, Altman PM, Barnetson RS. Tea tree oil in the treatment of tinea pedis. Australas J Dermatol. 1992;33:145-149. Buck DS, Nidorf DM, Addino JG. Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotrimazole. J Fam Pract. 1994;38:601-605. Caporaso N, Smith SM, Eng RH. Antifungal activity in human urine and serum after ingestion of garlic (Allium sativum). Antimicrob Agents Chemother. 1983;23:700-702. Agarwal KC. Therapeutic actions of garlic constituents. Med Res Rev. 1996;16:111-124. Hughes BG, Lawson LD. Antimicrobial effects of Allium sativum (garlic), Allium ampeloprasum L (elephant garlic), and Allium cepa (onion), garlic compounds and commercial ...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.

Allyl compounds | definition of Allyl compounds by Medical dictionaryAllyl compounds | definition of Allyl compounds by Medical dictionary

Allyl compounds explanation free. What is Allyl compounds? Meaning of Allyl compounds medical term. What does Allyl compounds ... Looking for online definition of Allyl compounds in the Medical Dictionary? ... allyl. (redirected from Allyl compounds). Also found in: Dictionary, Thesaurus. al·lyl. (alil), The monovalent radical, CH2= ... Allyl compounds , definition of Allyl compounds by Medical dictionary https://medical-dictionary.thefreedictionary.com/Allyl+ ...
more infohttps://medical-dictionary.thefreedictionary.com/Allyl+compounds

Anion Exchangers Based on Allyl Compounds and Some Nitrogen- and Oxygen-Containing Monomers and Oligomers, Russian Journal of...Anion Exchangers Based on Allyl Compounds and Some Nitrogen- and Oxygen-Containing Monomers and Oligomers, Russian Journal of...

"Anion Exchangers Based on Allyl Compounds and Some Nitrogen- and Oxygen-Containing Monomers and Oligomers, Russian Journal of ... Anion Exchangers Based on Allyl Compounds and Some Nitrogen- and Oxygen-Containing Monomers and Oligomers. Ergozhin, E.; Chalov ... Anion Exchangers Based on Allyl Compounds and Some Nitrogen- and Oxygen-Containing Monomers and... Ergozhin, E.; Chalov, A.; ... Anion Exchangers Based on Allyl Compounds and Some Nitrogen- and Oxygen-Containing Monomers and Oligomers. ...
more infohttps://www.deepdyve.com/lp/springer_journal/anion-exchangers-based-on-allyl-compounds-and-some-nitrogen-and-oxygen-z093gFkR2t

Allyl Compounds - Allyl Heptanoate Manufacturer from VapiAllyl Compounds - Allyl Heptanoate Manufacturer from Vapi

Allyl Heptanoate, Allyl Phenoxyacetate, Coconut Amine and Diallylamine offered by Triveni Interchem Private Limited (Group Of ... Allyl Compounds. We are a leading Manufacturer of allyl heptanoate, allyl phenoxyacetate, coconut amine, diallylamine and ... It is chemical compounds.. Application / Uses Preparation. We are the leading wholesaler of Diallylamine compound with selling ... Allyl Heptanoate (142-19-8) is colourless liquid. also known as Heptanoic Acid Allyl Ester . Additional Information: ...
more infohttp://www.triveniinterchem.com/allyl-compounds.html

Allyl sulfur compounds and cellular detoxification system: effects and perspectives in cancer therapy | SpringerLinkAllyl sulfur compounds and cellular detoxification system: effects and perspectives in cancer therapy | SpringerLink

Natural organosulfur compounds (OSCs) have been shown to have chemopreventive effects and to suppress the proliferation of ... are needed to identify the molecular targets and modes of action of these natural compounds, the allyl sulfur compounds can ... Several modes of action of these compounds have been proposed, and it seems likely that the rate of clearance of allyl sulfur ... The aim of this review is to focus attention on the effects of natural allyl sulfur compounds on the cell detoxification system ...
more infohttps://link.springer.com/article/10.1007%2Fs00726-010-0522-6

Allyl group - WikipediaAllyl group - Wikipedia

Allyl compounds[edit]. Many substituents can be attached to the allyl group to give stable compounds. Commercially important ... The middle MO labeled Ψ2 is singly occupied in the allyl radical. In the allyl cation Ψ2 is unoccupied and in the allyl anion ... In 1844, Theodor Wertheim isolated an allyl derivative from garlic oil and named it "Schwefelallyl".[3][4] The term allyl ... and allylindium compounds are commonly used by organic chemists to introduce allyl groups.[9] ...
more infohttps://en.wikipedia.org/wiki/Allyl_group

Pd(O2CCF3)2/benzoquinone: a versatile catalyst system for the decarboxylative olefination of arene carboxylic acids.Pd(O2CCF3)2/benzoquinone: a versatile catalyst system for the decarboxylative olefination of arene carboxylic acids.

Allyl Compounds. Benzoquinones / chemistry*. Carboxylic Acids / chemistry*. Catalysis. Combinatorial Chemistry Techniques. ... 0/Alkenes; 0/Allyl Compounds; 0/Benzoquinones; 0/Carboxylic Acids; 106-51-4/benzoquinone; 7440-05-3/Palladium ...
more infohttp://www.biomedsearch.com/nih/Versatile-Catalyst-System-Decarboxylative-Olefination/19432465.html

TNO Repository search for: subject:Glutathione transferaseTNO Repository search for: subject:'Glutathione transferase'

Nutrition · Allyl Compounds · Animals · Cytoplasm · Eugenol · Glutathione Transferase · Humans · Isoenzymes · Kidney · Liver · ... Chemicals/CAS: 2-allylphenol, 1745-81-9; 4-propylphenol, 645-56-7; Allyl Compounds; Eugenol, 97-53-0; Glutathione Transferase, ... The MALDI spectra obtained with the neutral compounds ANA (pH 4.4), NA (pH 6.4) and AMNP (pH 7.1) as matrices contain only ... Although it is very difficult on the basis of the enzyme inducing or inhibiting properties of dietary compounds, especially to ...
more infohttps://repository.tudelft.nl/search/tno/?q=subject%3A%22Glutathione%20transferase%22

The EPA National Library Catalog | EPA National Library Network | US EPAThe EPA National Library Catalog | EPA National Library Network | US EPA

Aldehydes--Carcinogens ; Aldehydes--Toxicology ; Allyl Compounds--toxicity ; Epoxy Compounds ; Ethers, Cyclic--toxicity ; ... Allyl compounds, aldehydes, epoxides, and peroxides.. CORP Author. IARC Working Group on the Evaluation of the Carcinogenic ... Aromatic compounds--Toxicology--Congresses. ; Carcinogens--Congresses. ; Mutagenesis--Congresses. Holdings. Library. Call ... Aldehydes--Toxicology--Congresses ; Epoxy compounds--Toxicology--Congresses ; Peroxides--Toxicology--Congresses ; Carcinogens-- ...
more infohttps://cfpub.epa.gov/ols/catalog/advanced_bibliography.cfm?FIELD1=SUBJECT&INPUT1=Carcinogens%20Congresses&TYPE1=EXACT&LOGIC1=AND&COLL=&SORT_TYPE=MTIC&start_row=25

Allyl isothiocyanate, a compound present in human diets, found to induce cell toxicity in breast cancer cell linesAllyl isothiocyanate, a compound present in human diets, found to induce cell toxicity in breast cancer cell lines

Isothiocyanates are compounds that have been shown to exhibit anticancer effects, such […] ... a compound present in many cruciferous vegetables, on human breast cancer cell lines MCF-7 and MDA-MB-231. The results were ... a team of researchers from Taiwan examined the effect of allyl isothiocyanate (AITC), ... Allyl isothiocyanate, a compound present in human diets, found to induce cell toxicity in breast cancer cell lines. ...
more infohttps://food.news/2019-06-25-allyl-isothiocyanate-induces-cell-toxicity-breast-cancer.html

Plus itPlus it

Allyl compounds, aldehydes, epoxides and peroxides. In: IARC monographs on the evaluation on the carcinogenic risk of chemicals ...
more infohttp://cebp.aacrjournals.org/content/17/10/2846

Impact of Secondary Interactions in Asymmetric CatalysisImpact of Secondary Interactions in Asymmetric Catalysis

cetic acid; allyl acetate; allyl compound; hydroxide; ligand; malonic acid; oxazoline derivative; palladium; unclassified drug ...
more infohttp://kth.diva-portal.org/smash/record.jsf?pid=diva2:12045

Synthesis of heterocyclic and carbocyclic compounds via alkynyl, allyl, and propargyl organometallics of cyclopentadienyl iron,...Synthesis of heterocyclic and carbocyclic compounds via alkynyl, allyl, and propargyl organometallics of cyclopentadienyl iron,...

... allyl, and propargyl organometallics of cyclopentadienyl iron, molybdenum, and tungsten complexes ... Synthesis of heterocyclic and carbocyclic compounds via alkynyl, ... of carbocyclic and heterocyclic compounds using allyl, ... Subjects list: Research, United States, Analysis, Usage, Heterocyclic compounds, Organic compounds, Organic compound synthesis ... Synthesis of heterocyclic and carbocyclic compounds via alkynyl, allyl, and propargyl organometallics of cyclopentadienyl iron ...
more infohttp://www.readabstracts.com/Chemistry/Synthesis-of-heterocyclic-and-carbocyclic-compounds-via-alkynyl-allyl-and-propargyl-organometallics-.html

Effects of natakalim on plasma concentration of endothe | Open-iEffects of natakalim on plasma concentration of endothe | Open-i

Allyl Compounds/pharmacology*. *Cardiomegaly/drug therapy*. *Endothelium, Vascular/drug effects*/physiopathology. *Myocardial ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4199399_IJMM-34-05-1209-g04&req=4

Method for preparing a multi-layered polymeric composite and a     multi-layered composite produced thereby - Patent # 6682809 ...Method for preparing a multi-layered polymeric composite and a multi-layered composite produced thereby - Patent # 6682809 ...

... allyl compounds, such as allyl acetate.. The term "ABS terpolymer" is used generically herein not only to define a terpolymer ... These mercapto-olefin compounds are those as disclosed in U.S. Pat. No. 5,247,000 toAmick. Further, the methods of U.S. Pat. No ... Typically, themacromolecular organic compound may be used whenever facilitation of transport of monomer, or other ingredient, ... Macromolecular organic compounds having a hydrophobic cavity useful in the present invention include for example cyclodextrin ...
more infohttp://www.patentgenius.com/patent/6682809.html

Patente US7026372 - Enic compounds, sulfur-containing polyenic compound, sulfur-containing ... - Google PatentesPatente US7026372 - Enic compounds, sulfur-containing polyenic compound, sulfur-containing ... - Google Patentes

... and one or more enic compounds which composition is photocurable and can give a cured product having a high refractive index ... Concretely, it includes vinyl compounds, allyl compounds, acrylic compounds and methacrylic compounds. ... and a vinyl compound, an allyl compound, an acrylic compound and a methacrylic compound other than the formula (15). ... 2) allyl compounds obtained by substituting part or all of vinyl groups of the vinyl compounds of the above (1) with allyl ...
more infohttp://www.google.es/patents/US7026372?dq=flatulence

Patent US6927294 - Nitrogen-containing heterocycles - Google PatentsPatent US6927294 - Nitrogen-containing heterocycles - Google Patents

Nitrogen-containing heterocycles are prepared by reacting amino-carbonyl compounds that contain an amine moiety connected via a ... Functionalized nitrogen heterocyclic compounds, including benzodiazepines and azasugars, and synthetic methods for preparing ... An organoboron derivative, as defined herein, comprises a compound having a boron atom connected to at least one alkyl, allyl, ... The amino-carbonyl compound can be a compound of formulas 20 or 21, and the nitrogen heterocycle compound can be an azasugar of ...
more infohttp://www.google.com/patents/US6927294?dq=6,563,928

Extração e caracterização parcial de peroxidase de folhas de Copaifera langsdorffii Desf.Extração e caracterização parcial de peroxidase de folhas de Copaifera langsdorffii Desf.

Allyl compounds, aldehydes, epoxides and peroxides, IARC, Lyon, France 36, 1985. [ Links ]. 13. JACKSON, P.; RICARDO, C. P. P. ...
more infohttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612007000200002&lang=pt

Patent US4456643 - Decorative laminate - Google PatentsPatent US4456643 - Decorative laminate - Google Patents

... allyl compounds such as allyl acetate, allyl chloride, allyl ethyl ether, and the like; conjugated and cross-conjugated ... The resinous compound of the seal coat is preferably a vinyl resin. Suitable resins are commercially available in the form of ... Such materials as phenolformaldehyde and phenol-urea resins, polymerized vinyl compounds, such as polyvinyl chloride, polyvinyl ... cyclic unsaturated compounds such as styrene, chlorostyrene, coumarone, vinyl pyridine and the like; maleic and fumaric acid ...
more infohttp://www.google.com.au/patents/US4456643

Patents filed at Oct 11 2016 | Ono pincer ligands and ono pincer ligand comprising metal complexes | Patents.comPatents filed at Oct 11 2016 | Ono pincer ligands and ono pincer ligand comprising metal complexes | Patents.com

Organosilicon compound, adhesive composition and article , Method for producing hydrosilanes containing carbon , ... Allyl compound and method for producing the same. The allyl compound of the present invention is represented by general formula ... Inhibitor compounds of phosphodiesterase type 10A. The present invention relates to compounds of the formula I, the N-oxides, ... As a result of studies on compounds having FGFR inhibitory action,... US-9,464,076. Benzothiophene derivative. Compounds having ...
more infohttp://patents.com/isd-20161011-p81.html

3,4,5-Trimethoxyamphetamine - Everything2.com3,4,5-Trimethoxyamphetamine - Everything2.com

The compounds missing that methyl group on the 4-oxygen are famous. The allyl material is eugenol, 4-allylguaiacol, and it is ... The parent compound is myristicin, 5-allyl-1-methoxy-2,3-methylenedioxybenzene, and the source of this is nutmeg (or the ... This allyl compound is found in turpentine, anise, fennel, bay, tarragon, and basil. Its smell is light, and reminiscent of ... The allyl-2,4,5-isomer is called asaricin. It, and its propenyl-isomer, carpacin, are from the Carpano tree which grows in the ...
more infohttps://everything2.com/title/3%252C4%252C5-Trimethoxyamphetamine

Pemphigus in the eastern region of Turkey
	Pemphigus in the eastern region of Turkey

In vitro acantholysis by allyl compounds of the genus Allium. Dermatology. 1995. 190:p. 197-202 ... claim that garlic compounds with stable disulfide and thiol groups in their molecule are capable of inducing acantholysis in ...
more infohttps://www.termedia.pl/Pemphigus-in-the-eastern-region-of-Turkey,7,37479,1,1.html

Patente US5879805 - Gas phase polymerization of vinylpolybutadiene - Google PatentesPatente US5879805 - Gas phase polymerization of vinylpolybutadiene - Google Patentes

... an organoaluminum compound, and optionally a modifier (d) can be included in the catalyst composition. There is also provided a ... a compound selected from the group consisting of a phosphine, a xanthogen, a thiocyanide, a carbon disulfide, and mixtures ... vinyl compounds; cyclopentadienyl compounds; π-allyl compounds; 1,3-diketones such as acetylacetone and acetoacetic acid, and ... a) a cobalt compound;. (b) a compound selected from the group consisting of a phosphine compound, a xanthogen compound, a ...
more infohttp://www.google.es/patents/US5879805?dq=flatulence

US20060137603A1 - Methods and apparatus for rapid crystallization of biomolecules 
        - Google PatentsUS20060137603A1 - Methods and apparatus for rapid crystallization of biomolecules - Google Patents

... vinyl pyrrolidone and other low-molecular weight vinyl and allyl compounds; vinylic, allylic, acrylic and methacrylic ... The term "biomolecule" as used herein refers to any compound, either man-made or natural, that has an observable effect on a ... For example, addition of allyl glycidyl ether to hydroxyl groups is known, as is esterification of hydroxyls with acids, ... Candidate non-acrylamide monomers can include, e.g., allyl alcohol, HEMA (hydroxyethyl [methyl] acrylate), polyethylene glycol ...
more infohttps://patents.google.com/patent/US20060137603A1/en

CDC - NIOSH Publications and Products - Carcinogenic Effects of Exposure to Propylene Oxide (89-111)CDC - NIOSH Publications and Products - Carcinogenic Effects of Exposure to Propylene Oxide (89-111)

IARC [1985]. IARC Monographs on the evaluation of carcinogenic risk of chemicals to humans: Allyl compounds, aldehydes, ... Hine C, Rowe VK, White ER, Darmer KI Jr, Youngblood GT [1981]. Epoxy compounds. In: Pattys Industrial hygiene and toxicology. ... and cleaning compounds. Propylene oxide is also increasingly considered as a substitute for ethylene oxide as a sterilant for ...
more infohttps://www.cdc.gov/niosh/docs/89-111/default.html
  • In this study, a team of researchers from Taiwan examined the effect of allyl isothiocyanate (AITC), a compound present in many cruciferous vegetables, on human breast cancer cell lines MCF-7 and MDA-MB-231. (food.news)
  • Nikitina, A. 2004-10-13 00:00:00 Anion exchangers containing different basic groups and having good physicochemical and sorption properties were prepared by polycondensation of polyallylamine and various allyl halides, diglycidyl ethers of dihydroxybenzenes, and aromatic amines with some aliphatic polyamines. (deepdyve.com)
  • Nitrogen-containing heterocycles are prepared by reacting amino-carbonyl compounds that contain an amine moiety connected via a linker to a carbonyl moiety with an organoboron derivative. (google.com)
  • A direct interaction of the garlic allyl sulfur compounds with proteins involved in the detoxification system was studied in order to support the hypothesis that proteins possessing reactive thiol groups and that are involved in the detoxification system and in the cellular redox homeostasis, are likely the preferential targets of these compounds. (springer.com)
  • A review of studies published in the Chinese Journal of Natural Medicines confirmed that aged garlic can be used as a promising daily food supplement for preventing and treating cancer because of its compound called S-allylmercaptocysteine (SAMC). (naturalnews.com)
  • The present invention relates to a novel sulfur-containing polyenic compound, a sulfur-containing polythiol compound and photocurable compositions of these, which are useful for optical materials such as a spectacle lens, a prism, an optical fiber, an information recording substrate and a filter and useful for coating materials, adhesives and encapsulants for optical materials and relates to high-refractive-index cured products obtainable from the above photocurable compositions. (google.es)
  • This document relates to compounds and compositions useful for treating cancers, such as brain and nervous system cancers. (patents.com)
  • This invention is in the area of improved compounds, compositions and methods of transiently protecting healthy cells, and in particular hematopoietic stem and. (patents.com)
  • The biochemical transformation of the OSCs in the cell and their adducts with thiol functional groups of these proteins, could be considered relevant events to uncover the anticancer properties of the allyl sulfur compounds. (springer.com)
  • Although additional studies, using proteomic approaches and transgenic models, are needed to identify the molecular targets and modes of action of these natural compounds, the allyl sulfur compounds can represent potential ideal agents in anticancer therapy, either alone or in association with other antitumor drugs. (springer.com)
  • Isothiocyanates are compounds that have been shown to exhibit anticancer effects, such as the induction of apoptosis in different human cancer cell lines. (food.news)
  • Methods for the metal-mediated synthesis of seven to nine-membered ring compounds via ring-closing metathesis, ring-expansion, cyclization, cycloaddition, and annulation reactions are described. (readabstracts.com)
  • Compounds containing the C=C−CH 2 −C=C linkages, e.g. linoleic acid derivatives, are prone to autoxidation, which can lead to polymerization or form semisolids. (wikipedia.org)
  • Stable crystalline forms of a compound represented by the formula (IA): ##STR00001## an acid addition salt, and/or a solvate thereof are provided by the. (patents.com)
  • The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts thereof. (patents.com)
  • The invention provides compounds of formula I: ##STR00001## or a salt thereof as described herein. (patents.com)
  • An allyl group is a substituent with the structural formula H 2 C=CH−CH 2 R, where R is the rest of the molecule. (wikipedia.org)
  • An organosilicon compound having a hydrolyzable silyl group and a catechol group in the molecule is novel. (patents.com)
  • A method for producing a high-purity nitrogen-containing heterocyclic compound includes: a process (a) and a process (b): (a) a process of mixing a mixture. (patents.com)
  • Oxidative addition of the silane and the insertion of the allyl compound into the Pt-H bond turned out to be the crucial, selectivity-determining steps within the catalytic cycle. (tum.de)
  • In sum, the results demonstrated that AITC, a compound that is ordinarily present in human diets, may be used to treat various cancers. (food.news)
  • Through this aging process, unique and powerful compounds like SAMC and other S-allyl compounds are produced. (naturalnews.com)