Synthetic analogs of the naturally occurring insecticides cinerin, jasmolin, and pyrethrin. (From Merck Index, 11th ed)
A plant species of the genus CHRYSANTHEMUM, family ASTERACEAE. The flowers contain PYRETHRINS, cinerolones, and chrysanthemines which are powerful contact insecticides. Most in the old Pyrethrum genus are reclassified to TANACETUM; some to other ASTERACEAE genera.
The active insecticidal constituent of CHRYSANTHEMUM CINERARIIFOLIUM flowers. Pyrethrin I is the pyretholone ester of chrysanthemummonocarboxylic acid and pyrethrin II is the pyretholone ester of chrysanthemumdicarboxylic acid monomethyl ester.
Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.

Mammalian voltage-gated calcium channels are potently blocked by the pyrethroid insecticide allethrin. (1/13)

Pyrethroids are commonly used insecticides for both household and agricultural applications. It is generally reported that voltage-gated sodium channels are the primary target for toxicity of these chemicals to humans. The phylogenetic and structural relatedness between sodium channels and voltage-gated calcium (Ca) channels prompted us to examine the effects of the type 1 pyrethroid allethrin on the three major classes of mammalian calcium channels exogenously expressed in human embryonic kidney 293 cells. We report that all classes of mammalian calcium channels are targets for allethrin at concentrations very similar to those reported for interaction with sodium channels. Allethrin caused blockade with IC(50) values of 7.0 microM for T-type alpha(1G) (Ca(v)3.1), 6.8 microM for L-type alpha(1C) (Ca(v)1.2), and 6.7 microM for P/Q-type alpha(1A) (Ca(v)2.1) channels. Mechanistically, the blockade of calcium channels was found to be significantly different than the prolonged opening of mammalian sodium channels caused by pyrethroids. In all calcium channel subtypes tested, allethrin caused a significant acceleration of the inactivation kinetics and a hyperpolarizing shift in the voltage dependence of inactivation. The high-voltage-activated P/Q- and L-type channels showed a frequency of stimulation-dependent increase in block by allethrin, whereas the low-voltage-activated alpha(1G) subtype did not. Allethrin did not significantly modify the deactivation kinetics or current-voltage relationships of any of the calcium channel types. Our study indicates that calcium channels are another primary target for allethrin and suggests that blockade of different types of calcium channels may underlie some of the chronic effects of low-level pyrethroid poisoning.  (+info)

Metofluthrin: a potent new synthetic pyrethroid with high vapor activity against mosquitoes. (2/13)

(1R)-trans-Norchrysanthemic acid fluorobenzyl esters are synthesized and their structure-activity relationships are discussed. These esters show outstanding insecticidal activity against mosquitoes. In particular, the 2,3,5,6-tetrafluoro-4-methoxymethylbenzyl analog (metofluthrin) exhibits the highest potency, being approximately forty times as potent as d-allethrin in a mosquito coil formulation when tested against southern house mosquitoes (Culex quinquefasciatus). Metofluthrin also exhibits a significant vapor action at room temperature.  (+info)

Efficacy of thermal fog application of deltacide, a synergized mixture of pyrethroids, against Aedes aegypti, the vector of dengue. (3/13)

We evaluated the efficacy of indoor and peridomestic thermal fog applications of deltacide, a synergized mixture of pyrethroids (S-bioallethrin 0.7% w/v, deltamethrin 0.5% w/v and piperonyl butoxide 8.9% w/v) against adult populations of Aedes aegypti in Chennai, Tamil Nadu, India. We bioassayed adult caged mosquitoes, counted indoor resting and human landing adult mosquitoes and assessed the percentage of potential breeding sites with Aedes larvae. The bioassay mortalities indicated that the knockdown and killing effect was greater when fogging was applied inside houses rather than around them. Peridomestic thermal fogging reduced the resting and biting populations by 76% and 40%, respectively for the 3 days after treatment, whereas indoor fogging suppressed adult populations for 5 days.  (+info)

Ninety-day toxicity and one-generation reproduction study in rats exposed to allethrin-based liquid mosquito repellent. (4/13)

Rats exposed to liquid mosquito repellent (LMR) containing allethrin (3.6% w/w) 8-hrs/ day for a period of ninety days did not produce any signs of toxicity or death. Significant increases in relative weight of liver and adrenal in males, brain and thyroid in females were observed. No significant changes were noticed in clinical enzyme profile, gonadal enzymes and histopathology of vital organs except mild changes in the activities of liver and serum alkaline phosphates (ALP), testicular glucose-6-phosphate dehydrogenase (G-6PDH) and epididymal sorbitol dehydrogenase (SDH). Rats exposed to LMR for one generation had not produced changes in their reproductive indices such as fertility index, gestation index, live pups/ dam and sex ratio. There was no change in the preweanling evaluation of pups such as survival and growth index on post-natal days (PND) 0, 4, 7,14 and 21. No significant pathomorphological changes were observed in liver, brain, kidney and gonads of PND 21 pups. Absences of any major adverse effects in the adult as well as weanling rats suggest the safe use of allethrin-based LMR.  (+info)

Nationwide investigation of the pyrethroid susceptibility of mosquito larvae collected from used tires in Vietnam. (5/13)

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Lack of insecticidal effect of mosquito coils containing either metofluthrin or esbiothrin on Anopheles gambiae sensu lato mosquitoes. (6/13)

Use of mosquito coils for personal protection against malaria and mosquito nuisance is advocated under mosquito and malaria control programmes. We performed field studies of mosquito coils containing either metofluthrin or esbiothrin in experimental huts situated in Kamhororo village, Gokwe district, Zimbabwe. All tests were performed on 3-5 day old reared female Anopheles gambiae sensu lato mosquitoes. The burning times were 9hr 20min for mosquito coils containing metofluthrin and 8 hr for those containing esbiothrin and the results were significantly different (p = <0.001). The mean knock down rate for mosquito coils containing metofluthrin was 90% and that for esbiothrin was 73.3% and the results were significantly different (p = 0.00). Mosquito coils containing metofluthrin had a mean repellence of 92.7% as compared to 85.4% for esbiothrin and the results were not significantly different (p=0.27). The protection time as required by EPA (1999) was 6 hr for mosquito coils containing metofluthrin and 5 hr for those containing esbiothrin. The mean insecticidal effect of mosquito coils containing metofluthrin was 84% as compared to 83% for those containing esbiothrin and the results were not significantly different (p = 0.56). Both mosquito formulations could not be classified as having insecticidal effect since none of them met the 95% mortality rate criteria.  (+info)

Allethrin differentially modulates voltage-gated calcium channel subtypes in rat PC12 cells. (7/13)

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Divergent actions of the pyrethroid insecticides S-bioallethrin, tefluthrin, and deltamethrin on rat Na(v)1.6 sodium channels. (8/13)

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Allethrin is a synthetic insecticide that belongs to the class of chemicals called pyrethroids. It is derived from the natural pyrethrins, which are extracted from chrysanthemum flowers. Allethrin acts on the nervous system of insects, causing paralysis and death. It is used to control a wide variety of insect pests in both indoor and outdoor settings, including mosquitoes, flies, and cockroaches. However, it can also be toxic to non-target organisms, including fish and beneficial insects, and may cause skin and eye irritation in humans. Therefore, it should be used with caution and according to the manufacturer's instructions.

Chrysanthemum cinerariifolium is a specific species of chrysanthemum flower that is native to Asia. It is also known as the "Pyrethrum daisy" or "Dalmatian chrysanthemum." This plant is most well-known for its production of pyrethrin, a natural insecticide. The dried flowers of this species contain high concentrations of pyrethrins, which are potent neurotoxins to insects but considered low in toxicity to mammals and birds.

The medical definition of Chrysanthemum cinerariifolium is related to its use as a traditional herbal medicine in some cultures. The flowers are used to make teas and tinctures, which have been used to treat various conditions such as fever, headache, respiratory infections, and skin diseases. However, it's important to note that the scientific evidence supporting these uses is limited, and more research is needed before any definitive medical claims can be made.

It's also worth noting that Chrysanthemum cinerariifolium extracts and pyrethrins are used in some commercial insecticides and pesticides. These products are used to control a wide variety of pests, including mosquitoes, fleas, ticks, and agricultural pests. Pyrethrin-based insecticides are considered to be relatively safe for use around humans and animals, but they can be toxic to fish and other aquatic organisms, so they must be used with caution in or near bodies of water.

Pyrethrins are a group of naturally occurring organic compounds extracted from the flowers of Chrysanthemum cinerariaefolium and Chrysanthemum coccineum. They have been used for centuries as insecticides due to their ability to disrupt the nervous system of insects, leading to paralysis and death. Pyrethrins are composed of six esters, pyrethrin I and II, cinerin I and II, and jasmolin I and II, which have different insecticidal properties but share a similar mode of action. They are commonly used in household insect sprays, pet shampoos, and agricultural applications to control a wide range of pests. However, pyrethrins can be toxic to fish and some beneficial insects, so they must be used with caution.

Insecticides are substances or mixtures of substances intended for preventing, destroying, or mitigating any pest, including insects, arachnids, or other related pests. They can be chemical or biological agents that disrupt the growth, development, or behavior of these organisms, leading to their death or incapacitation. Insecticides are widely used in agriculture, public health, and residential settings for pest control. However, they must be used with caution due to potential risks to non-target organisms and the environment.

Allethrin I and allethrin II differ by having a methyl group and a methyl ester, respectively, on one terminus. Each of these ... Allethrin was the first pyrethroid. They are commonly used in ultra-low volume sprays for outdoor mosquito control, and in many ... The allethrins are a group of related synthetic compounds used in insecticides. They are classified as pyrethroids, i.e. ... Allethrins are toxic to cats because they either do not produce, or produce less of certain isoforms of glucuronosyltransferase ...
Allethrin: sometimes d-trans-allethrin, the first synthetic pyrethroid. Esbiothrin: a form of allethrin. Dimefluthrin: a novel ...
The initial active ingredient was allethrin, the first synthetic pyrethroid. Raid derivatives aimed at particular invertebrate ... "Allethrins - an overview , ScienceDirect Topics". www.sciencedirect.com. Retrieved 2022-02-20. "SC Johnson". SC Johnson - ...
It is also shown that inhaling d-trans-Allethrin can irritate the nose, throat and lungs. High exposure may cause headache, ... Mortein "Insect Seeking Fly Spray" uses the active ingredients Allethrin (2.09 g/kg) and Resmethrin (0.39 g/kg), both ... "Chronic exposure to pyrethroid-based allethrin and prallethrin mosquito repellents alters plasma biochemical profile". ...
Many synthetic pyrethroids, for example the allethrins, are esters of all four stereoisomers. Staudinger and Ružička named ...
It consists of two of the eight stereoisomers of allethrin I in an approximate ratio of 1:1. The name Bioallethrin is a ... Allethrins, Allyl compounds, All stub articles, Antiinfective agent stubs). ...
Allethrin, the first pyrethroid synthesized Bifenthrin, active ingredient of Talstar, Capture, Ortho Home Defense Max, and ...
... acetoprole acrinathrin acrylonitrile a-ecdysone afidopyropen afoxolaner alanycarb aldicarb aldoxycarb aldrin allethrin allicin ...
... allethrin MeSH D02.455.849.575.812.636 - permethrin MeSH D02.455.849.575.875 - thymol MeSH D02.455.849.575.875.200 - bromthymol ...
Allantoin Allethrin α-Amanatin, see Alpha-amanitin Amino acid Amylase (also see α-amylase) Anabolic steroid Anandamide (ANA) ...
Allethrins, Total synthesis). ...
Allethrins, All stub articles, Ketone stubs). ...
Allethrins, Plant toxin insecticides, Biological pest control). ...
Allethrins, Propargyl compounds). ...
Allethrin I and allethrin II differ by having a methyl group and a methyl ester, respectively, on one terminus. Each of these ... Allethrin was the first pyrethroid. They are commonly used in ultra-low volume sprays for outdoor mosquito control, and in many ... The allethrins are a group of related synthetic compounds used in insecticides. They are classified as pyrethroids, i.e. ... Allethrins are toxic to cats because they either do not produce, or produce less of certain isoforms of glucuronosyltransferase ...
Effect of Red Seaweed (Euchema cottonii) Powder Administration To The Quantity and Quality of Spermatozoa of Allethrin-Exposed ... Powder Administration To The Quantity and Quality of Spermatozoa of Allethrin-Exposed House Mice. In: 2nd national and ...
d-Allethrin. D&C Orange 4. D&C Red 17. D&C Red 33. D&C Violet 2. D&C Yellow #10. D&C Yellow 11. D&C Yellow 7. D-Cis/Trans ... Allethrin. DEA-Cetyl Phosphate. Dearomatized Alkanes. Decyl Glucoside. Decyl Oleate. Decylamine Oxide. DEET. Deltamethrin. ...
d-cis-trans Allethrin. *d-trans Allethrin. *Bifenthrin. *Bioallethrin. *Bioallethrin S-cyclopentenyl ...
Examples of pyrethroids include: allethrin, cypermethrin, permethrin, phenothrin, pyrethrins, and tetremethrin. There may be ...
We also analyzed prescribing data for allethrin, benzyl benzoate, crotamiton, ivermectin, lindane, and permethrin linked to ...
Point mutations in domain III of a Drosophila neuronal Na channel confer resistance to allethrin. Insect Biochemistry and ...
Pesticide safety is always a hot topic, from Alar on apples, malathion and sevin in the garden, allethrin and cinerin in ant ...
Many of these are combination products that include a fast-acting, short-lived ingredient (e.g., allethrin, tetramethrin) with ...
Derivatives of Pyrethrins (allethrin, resmethrin, sumithrin, tetramethrin) - Like pyrethrins, these products destabilize nerve ...
국립환경과학원공고제2022-501호. 「승인유예대상 기존살생물물질의 지정」 고시를 일부 개정함에 있어 그 취지와 내용을 국민에게 미리 알려 이에 대한 의견을 듣고자 「행정절차법」 제46조에 따라 다음과 같이 공고합니다.. 2022년 12월 13일. 국립환경과학원. 승인유예대상 기존살생물물질의 지정 고시 일부개정(안) 행정예고. 1. 개정 개요. 개정된 「생활화학제품 및 살생물제의 안전관리에 관한 법률」(20.3.24. 시행) 제18조제3항에 따라 신고받은 기존살생물물질을 승인유예대상 기존살생물물질로 추가지정 하고 제19조제3항 등에 따라 승인유예대상 기존살생물물질의 지정을 해제하고자 함.. 2. 주요 내용. 가. 기존 지정물질의 살생물제품유형 추가지정. - [별표] 중 "21", "100", "109", "153", "290"에 사용될 수 있는 살생물제품유형 추가지정 및 승인유예기간 ...
Allethrin. If youre unable to recognize the tabled ingredients, worry not. You will find them with brand names like Baygon, ...
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78. ALLETHRIN [ԱԼԵՏՐԻՆ] 29. ALCOHOLICS ANONYMOUS [ԱԼԿՈՀՈԼԻԿՆԵՐ ԱՆԱՆՈՒՆ] 79. ALLIED HEALTH PERSONNEL [ԲԺՇԿԱԿԱՆ ՕԺԱՆԴԱԿ ԱՆՁՆԱԿԱԶՄ ...
d-Allethrin method, TC, LV. Azimsulfuron method, TC, WG. Bioallethrin method, TC, LV. ...
Allethrin. Allethrins. Bornanes. Camphanes. Diterpenes, Abietane. Abietanes. Dolichol. Dolichols. D04 - Polycyclic Compounds ...
Allethrin. Allethrins. Bornanes. Camphanes. Diterpenes, Abietane. Abietanes. Dolichol. Dolichols. D04 - Polycyclic Compounds ...
Allethrin angel food cake. Cyfluthrin cookies to name a few.... All of them are to DIE for! ...
Allethrin inhibited the proliferation of HCE cells in a dose-dependent manner. In the presence of allethrin, cells showed ... Pyrethroids including allethrin are the most common commercial household insecticides. The detrimental effects caused by ... Allethrin toxicity on human corneal epithelial cells involves mitochondrial pathway mediated apoptosis. ... The present study was aimed to elucidate the effects of allethrin on the human corneal epithelial (HCE) cells. ...
Allethrins : health and safety guide, allethrin, d-allethrin, bioallethrin, S-bioallethrin. by World Health Organization , ...
Its Superior Active D-Trans Allethrin provides results like professional pest control treatment. It kills mosquitoes that may ... Its Superior Active D-Trans Allethrin provides results like professional pest control treatment. It kills mosquitoes that may ...
The pyrethroid insecticides fenvalerate and d-trans allethrin seem to antagonize the action of progesterone [65]. ...
Active ingredients] dL・d-T80-allethrin, potassium sorbate, sodium benzoate, colorant, talc, fragrance, mixed plant powder, 1 ...
... white camphor oil and camphor oil had good synergistic effects on allethrin, with the synergistic ratios of 1.292-1.364, and ... linaloe wood oil and lavender oil on allethrin in solid mosquito coil were determined using closed cylinder. Mixtures of ... the mixture of wintergreen oil and camphor oil (1∶1) had an obvious synergistic effect on allethrin. After selection of the ...
... products are powered by a Thermacell fuel cartridge which directs heat to a small mat infused with the repellent Allethrin, a ...
allethrin. Look at other dictionaries:. *. Allergy - Classification and external resources Hives are a common allergic symptom ...
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  • Its Superior Active D-Trans Allethrin provides results like professional pest control treatment. (vizaggrocers.com)
  • A partly enantiopure variant of allethrin I, consisting of only two stereoisomers in an approximate ratio of 1:1, is called bioallethrin. (wikipedia.org)
  • When outdoors, use area repellents (such as mosquito coils) containing metofluthrin or allethrin. (dartmouth-hitchcock.org)
  • Evaluates the risks to human health and the environment posed by exposure to allethrin, d-allethrin, bioallethrin, and s-bioallethrin. (who.int)
  • The most extensive section reviews the design and findings of experimental studies, with results given separately for allethrin, d-allethrin, bioallethrin, and s-bioallethrin in terms of eye irritation, skin irritation, and sensitization. (who.int)
  • 1989)‎. Allethrins : allethrin, d-allethrin, bioallethrin, S-bioallethrin / published under the joint sponsorship of the United Nations Environmnent Programme, the International Labour Organisation, and the World Health Organization. (who.int)
  • Piperonyl butoxide is also formulated with synthetic pyrethrin analogues, such as allethrin and tetramethrin. (nih.gov)
  • An insecticide containing diazinon and allethrin had been applied to the basement of the site, which housed a clothing retail operation. (cdc.gov)
  • Contains permethrin andbattery powered mouse trap to killrooms d-allethrin. (widagroup.net)
  • Biochemical and histological alterations induced by the smoke of allethrin based mosquito coil on mice model. (medscape.com)
  • Allethrin (coil) 0.1 and 1.6 per cent prallethrin (liquid) have been found to be effective repellents against Phlebotomus argentipes, the vector of Indian kalaazar. (nih.gov)
  • 4. Allethrin-induced genotoxicity and oxidative stress in Swiss albino mice. (nih.gov)
  • Because these allethrins are most commonly used indoors, data concerning effects on the environment are scarce. (who.int)
  • Because these allethrins are most commonly used indoors, and since these compounds are rapidly decomposed by sunlight, the report concludes that the use of allethrins is unlikely to pose an environmental hazard, except in the case of spillage or misuse. (who.int)