Allantoin: A urea hydantoin that is found in URINE and PLANTS and is used in dermatological preparations.Urate Oxidase: An enzyme that catalyzes the conversion of urate and unidentified products. It is a copper protein. The initial products decompose to form allantoin. EC 1.7.3.3.Hydantoins: Compounds based on imidazolidine dione. Some derivatives are ANTICONVULSANTS.UreohydrolasesTartronatesOxamic Acid: Amino-substituted glyoxylic acid derivative.Imidazolines: Compounds based on reduced IMIDAZOLES containing a single double bond.GlyoxylatesUrea: A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.Racemases and Epimerases: Enzymes that catalyze inversion of the configuration around an asymmetric carbon in a substrate having one (racemase) or more (epimerase) center(s) of asymmetry. (Dorland, 28th ed) EC 5.1.AmidohydrolasesUric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.Guanine Deaminase: An enzyme that catalyzes the deamination of guanine to form xanthine. EC 3.5.4.3.Nitrogen Compounds: Inorganic compounds that contain nitrogen as an integral part of the molecule.Membrane Transport Modulators: Agents that affect ION PUMPS; ION CHANNELS; ABC TRANSPORTERS; and other MEMBRANE TRANSPORT PROTEINS.Amidine-Lyases: These enzymes catalyze the elimination of ammonia from amidines with the formation of a double bond. EC 4.3.2.Nitrogen: An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.Suppositories: Medicated dosage forms that are designed to be inserted into the rectal, vaginal, or urethral orifice of the body for absorption. Generally, the active ingredients are packaged in dosage forms containing fatty bases such as cocoa butter, hydrogenated oil, or glycerogelatin that are solid at room temperature but melt or dissolve at body temperature.Anesthetics, Local: Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.Ointments: Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.Manufactured Materials: Substances and materials manufactured for use in various technologies and industries and for domestic use.Facility Regulation and Control: Formal voluntary or governmental procedures and standards required of hospitals and health or other facilities to improve operating efficiency, and for the protection of the consumer.United States Food and Drug Administration: An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.Cosmetics: Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)Investigational New Drug Application: An application that must be submitted to a regulatory agency (the FDA in the United States) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (From the "New Medicines in Development" Series produced by the Pharmaceutical Manufacturers Association and published irregularly.)Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Comfrey: Perennial herb Symphytum officinale, in the family Boraginaceae, used topically for wound healing. It contains ALLANTOIN, carotene, essential oils (OILS, VOLATILE); GLYCOSIDES; mucilage, resin, SAPONINS; TANNINS; triterpenoids, VITAMIN B12, and ZINC. Comfrey also contains PYRROLIZIDINE ALKALOIDS and is hepatotoxic if ingested.Artemisia: A plant genus of the family ASTERACEAE with strong-smelling foliage. It is a source of SANTONIN and other cytotoxic TERPENES.Boraginaceae: The Borage plant family is in the class Magnoliopsida, subclass Asteridae, order Lamiales. It is characterized by hairy foliage, usually alternate and simple; flowers are funnel-shaped or tubular. Some of the species contain PYRROLIZIDINE ALKALOIDS.Ginger: Deciduous plant rich in volatile oil (OILS, VOLATILE). It is used as a flavoring agent and has many other uses both internally and topically.Taraxacum: A plant genus of the family ASTERACEAE. Members contain chicoric and chlorogenic acids and germacrane- and eudesmane-type SESQUITERPENES.Drug Information Services: Services providing pharmaceutic and therapeutic drug information and consultation.Medical Assistance: Financing of medical care provided to public assistance recipients.Skin Cream: A water-soluble medicinal preparation applied to the skin.Uncompensated Care: Medical services for which no payment is received. Uncompensated care includes charity care and bad debts.Beneficence: The state or quality of being kind, charitable, or beneficial. (from American Heritage Dictionary of the English Language, 4th ed). The ethical principle of BENEFICENCE requires producing net benefit over harm. (Bioethics Thesaurus)Ice Cream: A frozen dairy food made from cream or butterfat, milk, sugar, and flavorings. Frozen custard and French-type ice creams also contain eggs.Rumen: The first stomach of ruminants. It lies on the left side of the body, occupying the whole of the left side of the abdomen and even stretching across the median plane of the body to the right side. It is capacious, divided into an upper and a lower sac, each of which has a blind sac at its posterior extremity. The rumen is lined by mucous membrane containing no digestive glands, but mucus-secreting glands are present in large numbers. Coarse, partially chewed food is stored and churned in the rumen until the animal finds circumstances convenient for rumination. When this occurs, little balls of food are regurgitated through the esophagus into the mouth, and are subjected to a second more thorough mastication, swallowed, and passed on into other parts of the compound stomach. (From Black's Veterinary Dictionary, 17th ed)Animal Feed: Foodstuff used especially for domestic and laboratory animals, or livestock.Dietary Proteins: Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS.Peptide Termination Factors: Proteins that are involved in the peptide chain termination reaction (PEPTIDE CHAIN TERMINATION, TRANSLATIONAL) on RIBOSOMES. They include codon-specific class-I release factors, which recognize stop signals (TERMINATOR CODON) in the MESSENGER RNA; and codon-nonspecific class-II release factors.Digestion: The process of breakdown of food for metabolism and use by the body.Gels: Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.Urbanization: The process whereby a society changes from a rural to an urban way of life. It refers also to the gradual increase in the proportion of people living in urban areas.Consumer Health Information: Information intended for potential users of medical and healthcare services. There is an emphasis on self-care and preventive approaches as well as information for community-wide dissemination and use.Oral Hygiene: The practice of personal hygiene of the mouth. It includes the maintenance of oral cleanliness, tissue tone, and general preservation of oral health.Income: Revenues or receipts accruing from business enterprise, labor, or invested capital.Oral Hygiene Index: A combination of the debris index and the dental calculus index to determine the status of oral hygiene.Powders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Developing Countries: Countries in the process of change with economic growth, that is, an increase in production, per capita consumption, and income. The process of economic growth involves better utilization of natural and human resources, which results in a change in the social, political, and economic structures.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Medication Errors: Errors in prescribing, dispensing, or administering medication with the result that the patient fails to receive the correct drug or the indicated proper drug dosage.Waiting Lists: Prospective patient listings for appointments or treatments.Medication Adherence: Voluntary cooperation of the patient in taking drugs or medicine as prescribed. This includes timing, dosage, and frequency.Developed Countries: Countries that have reached a level of economic achievement through an increase of production, per capita income and consumption, and utilization of natural and human resources.

Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. (1/150)

Members of the BMP family of signaling molecules display a high conservation of structure and function, and multiple BMPs are often coexpressed in a variety of tissues during development. Moreover, distinct BMP ligands are capable of activating common pathways. Here we describe the coexpression of two members of the 60A subfamily of BMPs, Bmp5 and Bmp7, at a number of different sites in the embryo from gastrulation onwards. Previous studies demonstrate that loss of either Bmp5 or Bmp7 has negligible effects on development, suggesting these molecules functionally compensate for each other at early stages of embryonic development. Here we show this is indeed the case. Thus we find that Bmp5;Bmp7 double mutants die at 10.5 dpc and display striking defects primarily affecting the tissues where these factors are coexpressed. The present analysis also uncovers novel roles for BMP signaling during the development of the allantois, heart, branchial arches, somites and forebrain. Bmp5 and Bmp7 do not appear to be involved in establishing pattern in these tissues, but are instead necessary for the proliferation and maintenance of specific cell populations. These findings are discussed with respect to potential mechanisms underlying cooperative signaling by multiple members of the TGF-beta superfamily.  (+info)

Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. (2/150)

A large body of experimental evidence supports the participation of two groups of extracellular proteases, matrix metalloproteinases (MMPs), and plasminogen activators/plasmin, in tissue remodeling in physiological and pathological invasion. In the late mouse placenta, several tissue remodeling and cell invasion processes take place. Spongiotrophoblast migration into maternal decidua, as well as decidual extracellular matrix remodeling require the coordinated action of extracellular proteolytic enzymes. Via Northern and in situ hybridization, we have analyzed the spatio-temporal expression patterns of members of the MMP family (stromelysin-3, gelatinases A and B), as well as their inhibitors TIMP-1, -2 and -3 in late murine placenta (days 10.5 to 18.5 of gestation). Gelatinase activity in placental extracts was assessed by substrate zymography. Gelatinase A and stromelysin-3 were found to be prominently expressed in decidual tissue; shortly after midpregnancy, the decidual expression patterns of gelatinase A and stromelysin-3 became overlapping with each other, as well as with the expression domain of TIMP-2. On the other hand, gelatinase B transcripts were expressed only by trophoblast giant cells at day 10.5, and were downregulated at later stages. TIMP-1 and TIMP-3 transcripts were detected in decidual periphery at day 10.5, while later the expression was restricted to the endometrial stroma and spongiotrophoblasts, respectively. The areas of stromelysin-3 expression were the same (giant trophoblasts) or adjacent (decidua) to those where urokinase (uPA) transcripts were detected, suggesting a possible cooperation between these proteinases in placental remodeling. We generated mice doubly deficient for stromelysin-3 and uPA, and report here that these mice are viable and fertile. Furthermore, these animals do not manifest obvious placental abnormalities, thereby suggesting the existence of compensatory/redundant mechanisms involving other proteolytic enzymes. Our findings document the participation of MMPs and their inhibitors in the process of late murine placenta maturation, and warrant the characterization of other members of the MMP family, like membrane type-MMPs, in this process.  (+info)

Investigation of cell culture media infected with viruses by pyrolysis mass spectrometry: implications for bioaerosol detection. (3/150)

Mass spectrometry coupled with a pyrolysis inlet system was used to investigate media from cell cultures infected with viruses. Cell culture media is an intricate mixture of numerous chemical constituents and cells that collectively produce complicated mass spectra. Cholesterol and free fatty acids were identified and attributed to lipid sources in the media (blood serum supplement and plasma membranes of host cells). These lipid moieties could be utilized as signature markers for rapidly detecting the cell culture media. Viruses are intracellular parasites and are dependent upon host cells in order to exist. Therefore, it is highly probable that significant quantities of media needed to grow and maintain viable host cells would be present if a viral agent were disseminated as an aerosol into the environment. Cholesterol was also detected from a purified virus sample, further substantiating its use as a target compound for detection. Implications of this research for detection of viral bioaerosols, using a field-portable pyrolysis mass spectrometer, is described.  (+info)

Overlapping positive and negative GATA factor binding sites mediate inducible DAL7 gene expression in Saccharomyces cerevisiae. (4/150)

Allantoin pathway gene expression in Saccharomyces cerevisiae responds to two different environmental stimuli. The expression of these genes is induced in the presence of allantoin or its degradative metabolites and repressed when a good nitrogen source (e. g. asparagine or glutamine) is provided. Three types of cis-acting sites and trans-acting factors are required for allantoin pathway gene transcription as follows: (i) UAS(NTR) element associated with the transcriptional activators Gln3p and Gat1p, (ii) URS(GATA) element associated with the repressor Dal80p, and (iii) UIS(ALL) element associated with the Dal82 and Dal81 proteins required for inducer-dependent transcription. Most of the work leading to the above conclusions has employed inducer-independent allantoin pathway genes (e.g. DAL5 and DAL3). The purpose of this work is to extend our understanding of these elements and their roles to inducible allantoin pathway genes using the DAL7 (encoding malate synthase) as a model. We show that eight distinct cis-acting sites participate in the process as follows: a newly identified GC-rich element, two UAS(NTR), two UIS(ALL), and three URS(GATA) elements. The two GATA-containing UAS(NTR) elements are coincident with two of the three GATA sequences that make up the URS(GATA) elements. The remaining URS(GATA) GATA sequence, however, is not a UAS(NTR) element but appears to function only in repression. The data provide insights into how these cis- and trans-acting factors function together to accomplish the regulated expression of the DAL7 gene that is observed in vivo.  (+info)

Clostridium innocuum: a glucoseureide-splitting inhabitant of the human intestinal tract. (5/150)

Glycosylureides were recently described as non-invasive markers of intestinal transit time. The underlying principle is an enzymatic splitting of (13)C-labelled ureides by intestinal bacteria. The (13)CO(2) released from the urea moiety of the glycosylureides can be measured in breath samples when the ingested tracer substrate reaches the caecum that is colonised with microbes. To date, the microbes that degrade glycosylureides are unknown. In order to identify the glucoseureide (GU)-splitting bacteria, 174 different strains of intestinal microbes obtained from five healthy adults were checked for their ability to degrade GU. The results of the microbial cultures and thin layer chromatography revealed that GU was exclusively degraded by Clostridium innocuum, belonging to the normal human intestinal microflora. C. innocuum probably synthesises a yet unknown enzyme that splits the glucose-urea bond. We suggest that the term glucoseureidehydrolase is the appropriate designation for this enzyme.  (+info)

Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli. (6/150)

Growth experiments with Escherichia coli have shown that this organism is able to use allantoin as a sole nitrogen source but not as a sole carbon source. Nitrogen assimilation from this compound was possible only under anaerobic conditions, in which all the enzyme activities involved in allantoin metabolism were detected. Of the nine genes encoding proteins required for allantoin degradation, only the one encoding glyoxylate carboligase (gcl), the first enzyme of the pathway leading to glycerate, had been identified and mapped at centisome 12 on the chromosome map. Phenotypic complementation of mutations in the other two genes of the glycerate pathway, encoding tartronic semialdehyde reductase (glxR) and glycerate kinase (glxK), allowed us to clone and map them closely linked to gcl. Complete sequencing of a 15.8-kb fragment encompassing these genes defined a regulon with 12 open reading frames (ORFs). Due to the high similarity of the products of two of these ORFs with yeast allantoinase and yeast allantoate amidohydrolase, a systematic analysis of the gene cluster was undertaken to identify genes involved in allantoin utilization. A BLASTP search predicted four of the genes that we sequenced to encode allantoinase (allB), allantoate amidohydrolase (allC), ureidoglycolate hydrolase (allA), and ureidoglycolate dehydrogenase (allD). The products of these genes were overexpressed and shown to have the predicted corresponding enzyme activities. Transcriptional fusions to lacZ permitted the identification of three functional promoters corresponding to three transcriptional units for the structural genes and another promoter for the regulatory gene allR. Deletion of this regulatory gene led to constitutive expression of the regulon, indicating a negatively acting function.  (+info)

Systematic review of comparative efficacy and tolerability of calcipotriol in treating chronic plaque psoriasis. (7/150)

OBJECTIVES: To evaluate the comparative efficacy and tolerability of topical calcipotriol in the treatment of mild to moderate chronic plaque psoriasis. DESIGN: Quantitative systematic review of randomised controlled trials. SUBJECTS: 6038 patients with plaque psoriasis reported in 37 trials. MAIN OUTCOME MEASURES: Mean difference in percentage change in scores on psoriasis area and severity index, and response rate ratios for both patients' and investigators' overall assessments of marked improvement or better. Adverse effects were estimated with the rate ratio, rate difference, and number needed to treat. RESULTS: Calcipotriol was at least as effective as potent topical corticosteroids, calcitriol, short contact dithranol, tacalcitol, coal tar, and combined coal tar 5%, allantoin 2%, and hydrocortisone 0.5%. Calcipotriol caused significantly more skin irritation than potent topical corticosteroids (number needed to treat to harm for irritation 10, 95% confidence interval 6 to 34). Calcipotriol monotherapy also caused more irritation than calcipotriol combined with a potent topical corticosteroid (6, 4 to 8). However, the number needed to treat for dithranol to produce lesional or perilesional irritation was 4 (3 to 5). On average, treating 23 patients with short contact dithranol led to one more patient dropping out of treatment owing to adverse effects than if they were treated with calcipotriol. CONCLUSIONS: Calcipotriol is an effective treatment for mild to moderate chronic plaque psoriasis, more so than calcitriol, tacalcitol, coal tar, and short contact dithranol. Only potent topical corticosteroids seem to have comparable efficacy at eight weeks. Although calcipotriol caused more skin irritation than topical corticosteroids this has to be balanced against the potential long term effects of corticosteroids. Skin irritation rarely led to withdrawal of calcipotriol treatment. Longer term comparative trials of calcipotriol versus dithranol and topical corticosteroids are needed to see whether these short term benefits are mirrored by long term outcomes such as duration of remission and improvement in quality of life.  (+info)

Ureide degradation pathways in intact soybean leaves. (8/150)

Ureides dramatically accumulate in shoots of N(2)-fixing soybean (Glycine max L. Merr.) under water deficit and this accumulation is higher in cultivars that have N(2) fixation that is sensitive to water deficit. One possible explanation is that ureide accumulation is associated with a feedback inhibition of nitrogenase activity. A critical factor involved in ureide accumulation is likely to be the rate of ureide degradation in the leaves. There exists, however, a controversy concerning the pathway of allantoic acid degradation in soybean. Allantoate amidinohydrolase was reported to be the pathway of degradation in studies using the cultivar Maple Arrow and allantoate amidohydrolase was the pathway that existed in the cultivar Williams. This investigation was undertaken to resolve the existence of these two pathways. An in situ technique was developed to examine the response of ureide degradation in leaf tissue to various treatments. In addition, the response of ureide accumulation and N(2) fixation activity was measured for intact plants in response to treatments that differentially influenced the two degradation pathways. The results from these studies confirmed that Maple Arrow and Williams degraded allantoic acid by different pathways as originally reported. The existence of two degradation pathways within the soybean germplasm opens the possibility of modifying ureide degradation to minimize the influence of soil water deficits on N(2) fixation activity.  (+info)

Two metabolism trials evaluated urinary allantoin excretion as a noninvasive marker of microbial crude protein flow from the rumen. In the first trial, both urinary allantoin excretion and duodenal purine flow increased as alfalfa intake increased. A positive linear relationship (r2 = .74) existed between the markers. In the second trial, an increase in the metabolizable energy supplied to the animal did not increase urinary allantoin excretion. We concluded that urinary allantoin excretion was an effective, noninvasive marker of microbial crude protein supply.
TY - JOUR. T1 - Antihypertensive action of allantoin in animals. AU - Chen, Mei Fen. AU - Tsai, Jo Ting. AU - Chen, Li Jen. AU - Wu, Tung Pi. AU - Yang, Jia Jang. AU - Yin, Li Te. AU - Yang, Yu Lin. AU - Chiang, Tai An. AU - Lu, Han Lin. AU - Wu, Ming Chang. PY - 2014. Y1 - 2014. N2 - The agonists of imidazoline I-1 receptors (I-1R) are widely used to lower blood pressure. It has been indicated that guanidinium derivatives show an ability to activate imidazoline receptors. Also, allantoin has a chemical stricture similar to guanidinium derivatives. Thus, it is of special interest to characterize the effect of allantoin on I-1R. In conscious male spontaneous hypertensive rats (SHRs), mean blood pressure (MBP) was recorded using the tail-cuff method. Furthermore, the hemodynamic analyses in catheterized rats were applied to measure the actions of allantoin in vivo. Allantoin decreased blood pressures in SHRs at 30 minutes, as the most effective time. Also, this antihypertensive action was shown in ...
The global Allantoin Market is anticipated to grow at a CAGR of over 6 % from 2016 to 2024 on account of the growing demands from various industries such as cosmetics, oral hygiene etc. Moreover, rising scope of applications of allantoin in the pharmaceutical products, such as eye drops and skin care creams, is also expected to drive the market growth during the forecast period. The global market is categorized as applications and regions.. The applications sector of the allantoin market includes cosmetics, pharmaceutical, and oral hygiene. The global market for allantoin was dominated by cosmetics sector in 2015. It is further expected to grow as a result of growing consumer awareness concerning potential benefits of the products. Plus, rapid urbanization along with the growing disposable income levels is also said to spur the sector growth during the estimated years. The pharma sector is also expected to have huge gains at over 6 % from 2016 to 2024. The growing customer awareness concerning ...
Allantoin + hydroquinone + tretinoin topical is used in the treatment of .get complete information about allantoin + hydroquinone + tretinoin topical including usage, side effects, drug interaction, expert advice along with medicines associated with allantoin + hydroquinone + tretinoin topical at 1mg.com
Allantoin produces its desirable effects by promoting healthy skin, stimulates new and healthy tissue growth. Allantoin is als. Allantoin Powder wholesale.
Pret Vevey Swiss Re!generation crema de maini protectia pielii (Allantoin, D-panthenol, Olive Oil) 100 ml Original. Cumpara acum Vevey Swiss Re!generation crema de maini protectia pielii (Allantoin, D-panthenol, Olive Oil) 100 ml la pretul de 9 lei. Produsele din gama Vevey Swiss Re!generation sunt Originale si se afla pe stoc. Cod produs VVSREGW_KHCR10. Plasati o comanda online de peste 100 lei si primiti un cadou gratuit. Cosmetice si Parfumuri Vevey Swiss Re!generation Originale si Ieftine. Produse Vevey Swiss Re!generation pentru femei si barbati la cel mai bun pret.. ...
MEDERMA SCAR CREAM + SPF 30 (Allantoin) drug information & product resources from MPR including dosage information, educational materials, & patient assistance.
Healing: Attributing to the keratolytic properties found in Allantoin, this compound can help shed extra and/or dead layers of skin found in the epidermis (upper layers) resulting in a soothing effect.. Moisturizing: Commonly experienced dry skin is usually caused by a loss of water in the epidermis. With Allantoin removing unnecessary and dead layers of the skin, other ingredients such as emollients, moisturizers, and humectants are able to more effectively work as intended; they are not absorbed by a layer of skin that is essentially non-effective. Allantoin is also considered to be an emollient, helping to trap moisture within the skin once applied.. Skin Protectant: With the review and approval of the Food and Drug Administration (FDA), Allantoin is considered to be a Skin Protectant Active Ingredient between concentrations of 0.5% to 2%. One way a skin protectant works is by creating a barrier that protects the underlying skin from irritants.. ...
Anodesyn ointment and suppositories contain lidocaine hydrochloride (previously known as lignocaine hydrochloride in the UK) and allantoin.
Nitrogen is an essential nutrient for all life forms. The emergence of cells able to transport, catabolize and synthesize a wide variety of nitrogenous compounds has thus been favored by evolutionary selective pressure [1]. As a consequence, the yeast Saccharomyces cerevisiae can use almost 30 distinct nitrogen-containing compounds [1].. Like most unicellular organisms, yeast transports and catabolizes good nitrogen sources in preference to poor ones. Nitrogen catabolite repression (NCR) refers to this selection mechanism [1, 2]. More specifically, NCR inhibits the transcriptional activation systems of genes needed to degrade poor nitrogen sources [2]. All known nitrogen catabolite pathways are regulated by four regulators (Gln3, Gat1, Dal80, and Deh1) [3]. The ultimate goal is to infer the complete nitrogen catabolite pathways.. In this context, bioinformatics approaches offer the possibility to identify a relatively small number of putative NCR genes [1, 2, 4]. Hence, biologists need only to ...
Ectoin gives protecting and stabilising effect also when applied to human cells. Therefore, it is used as an effective allergy relief; its use is also common in dermatology - mainly in relieving the symptoms and treatment of atopic Dermatitis. The studies in which Ectoin was used have confirmed that owing to its unique properties of binding water, this molecule moisturises the skin, reduces irritations and skin roughness. Thanks to its frequent use in treating allergic diseases, Ectoin has gained much recognition from outstanding specialists in the field of allergology and dermatology.. ALLANTOIN. The ingredient that exhibits anti-irritant and skin moisturising properties in our product, and which is responsible for skin protection is Allantoin - a diureide of glyoxylic acid, extracted naturally from the comfrey plant or derived from urea. Due to its affinity to proteins and ammonium character, Allantoin is also responsible for the removal of dead skin cells and for softening the skin. ...
We slightly heat up lime-tree hydrosol, dissolve water soluble sulfur and allantoin in it. Sulfur strengthens hair, stimulates its growth, and helps to get rid of dandruff. Allantoin softens and moisturizes skin, promotes detachment of dead cells of epidermis. Stimulating tissue regeneration allantoin allows the skin to assimilate active components from shampoos and balsams ...
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
24Seven is an e-pharmacy committed to safe, reliable and fast delivery of medicines, cosmetics as well as other medical products.
Juniper Russo, an eclectic autodidact, has been writing professionally since 2008. Her work has appeared in several online and print-based publications, including Animal Wellness. Russo regularly publishes health-related content and advocates an evidence-based, naturopathic approach to health care.. ...
The Lens serves nearly all of the patents in the world as open, annotatable digital public goods that are integrated with scholarly and technical literature along with regulatory and business data.
I really didnt expect such a great post from you! I am 53 years old and have been using these pills for about a year already and couldnt be any happier. Sex lasts much longer, hard on is rock solid and my wife just cant get her hands off me! ...
You may also wish to search for items by Huffman, H. and Huffman. 124 matching references were found. Parks, G.S.; Huffman, H.M., Thermal data on organic compounds. IX. A study of the effect of unsaturation on the heat capacities, entropies and free energies of some hydrocarbons and other compounds, J. Am. Chem. Soc., 1930, 52, 4381-4391. [all data] Huffman, H.M.; Ellis, E.L., Thermal Data. II. The heats of combustion of l-cysteine, of l-cystine, «beta»-thiolactic acid and «beta»,«beta»-dithiodilactic acid, J. Am. Chem. Soc., 1935, 57, 41-46. [all data] Stiehler, R.D.; Huffman, H.M., Thermal data. IV. The heats of combustion of adenine, hypoxanthine, guanine, xanthine, uric acid, allantoin and alloxan, J. Am. Chem. Soc., 1935, 57, 1734-1740. [all data] Huffman, H.M.; Ellis, E.L.; Fox, S.W., Thermal data. VI. The heats of combustion and free energies of seven organic compounds containing nitrogen, J. Am. Chem. Soc., 1936, 58, 1728-1733. [all data] Huffman, H.M.; Fox, S.W.; Ellis, E.L., ...
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli ...
Glysolid 12 Pack - The Only Product You Need For Your Dry, Cracked Skin. GLYSOLID SKIN AND HAND CREAM with Glycerin and Allantoin is designed to treat sensitive, stressed and damaged skin.
Gives immediate wellbeing and protection to your hands, even for very dry and chapped hands.. Hands are a very important part of the body because, as they move, caress or work, they reveal our age. They therefore deserve continuous, delicate care as an essential part of any beauty regime. Thanks to its natural hydrating and calming ingredients this cream provides immediate wellbeing and protection to even the most dry and chapped hands. The skin will appear younger, softer and smoother from the first application.It is non-greasy and absorbs immediately.. COMPOSITION Jojoba Oil, Sallow extract, Allantoin, D-Panthenol, Vitamin E Acetate, Vitamin A, Palmitate.. 100 ml tube in box.. ...
ABC DEF GHI JKL MNO PQR STUV WXZY ABC Algae Extract: Normalizes skins moisture content and provides suppleness to the epidermis. Acts as an anti-inflammatory agent and antioxidant.Allantoin: Botanical extract known to be healing and soothing. An excellent temporary anti-irritant that aids the healing process of dama
Helix Aspersia Muller (Snail Secretion Filtrate) is the product which is naturally produced by snails to regenerate and repair its own skin when damaged. Helix Aspersia Muller is said to contain a a combination of components which have been seen improve the human skin. Some of these properties include Collagen, Allantoin, Vitamins, Elastin & Glucose Amino Glucan. This, combined with our star composition including Hyaluronic Acid Sodium & Glycerin helps to restore the skin softly, smoothly & delicately ...
The refreshing summer shower HITZEFREI with its fruity and fresh melon fragrance provides the long-awaited cooling off on a warm summer day. The high-quality formulation with wheat protein and allantoin cares for the skin and maintains its natural moisture balance.
extracts to formulas were as easy as just dumping some raw ingredients into powdered makeup and giving it a stir, then everybody would be doing it. Well, its not that easy and everybody is NOT doing it. The process of properly incorporating actives into a formula is actually quite complicated and delicate. Another point I feel worth mentioning is the percentages of botanicals and extracts used within formulas. Some of these recent articles and posts purport that if a botanical and/or extract is listed near the bottom of the ingredient deck, it is essentially rendered ineffective in a formula. PRIIAs ingredient decks are always listed in order of predominance. This means ingredients listed at the top of the deck are in the highest percentage within a formula and ingredients listed toward the bottom are at the lowest percentage within a formula. The TYPE of botanical or extract determines where it must be placed within our formulas. For example, our Japanese Green Tea and our Allantoin (derived ...
Transforms the hair and skin from dry and damaged by strong, shiny and smooth. Formula enriched with allantoin for smoothness and softness to skin and hair.
Enriched with Vitamin E, Yoko Spa Milk Bath Salt provides nourishment to your skin with pure Milk Derma White & Allantoin. It removes dirt deposits, a
Masken til den modne, slappe og tørre hud. Transparent Collagen Mask er en usynlig crememaske, der ikke stivner og ikke skal vaskes af. Anbefales at anvende om aftenen 2 gange ugentligt, hvor den påføres som natcreme i et tyndt lag. Den fjernes altså ikke, men fungerer som en ekstra nærende creme, der trænger effektivt ind i huden. Indeholder honning, hyaluronsyre, allantoin og mælkesyre. Hyaluronsyre er en naturlig bestanddel, der findes i bindevævet, og som booster huden mærkbart. Transparent Collagen Mask virker genopbyggende og efterlader huden blød og smidig. Sørger for en optimal fugtbalance og forbedrer hudens tilstand synligt. I perioder med en svækket hudtilstand kan masken også anvendes i et tyndt lag under dagcremen, ligesom der kan kombineres med Actiprotin under crememasken. ...
Long-lasting hydration fix for lips, enriched with Shea Butter, Camphor and Allantoin to condition, perfect and protect deep down.
The annotations from this paper are all in MF for GLN3. The paper shows data for function, how can you not make a Process annotation? It is okay to make an annotation to the term positive regulation of transcription from RNA Pol II... But this paper doesnt show evidence for the nitrogen catabolite repression part. So you have to stop with the positive regulation term. Also, based on inter-ontology relationship, a BP inference will be made from the MF annotation from this paper ...
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I made this simple Indian spinach dal the other day, I have found that I tend to alternative other cuisines be it Italian, Asian, British with Indian so hubby doesnt miss out on the food he enjoys. Also our little one will happily eat dal with rice. Dal is great tasting rich in protein and satisfying ...
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With the 3rd thread coming up to 40 pages, a request from Venara and a bit of free time I will be helping manage this thread and also help keep it clean with various UIs from each class.* I have a decent amount of healer Add-on knowledge and healer UIs are usually a bit different then most DPS classes.* The reason I believe its a great idea to breat the UIs down again by classes is because it gives others something to relate too, so they can see where your spells are and see what they should
Cells need to respond to a vast range of different disturbances and changes over small and large time scales. This can be disturbances in the form of molecules used to fight infectious states, changes in growth patterns ...
ATTENZIONE! Saremo CHIUSI per ferie dal 10 al 24 Agosto. Tutti gli ordini inseriti a partire dal 8 Agosto compreso verranno evasi a partire dal 24 Agosto. Buone vacanze! Dismiss. Skip to content ...
AspectTestingFramework.pdf 72.53 KB Biology-Inspired techniques for Self Organization in dynamic Networks.pdf 298.38 KB Bullet-High Bandwidth Data
garsejades precisessen esbardissesses aixaragallà gallofejàssiu coacerven acugulà acensaran aulari sobrealimento deslliguéssiu cercaran desclassaríem ...
Lobiettivo del corso, è lapprofondimento teorico-pratico delle problematiche legate al trattamento chirurgico delle patologie a carico dellapparato riproduttivo femminile mediante tecniche endoscopiche avanzate utilizzando le più innovative concezioni embrio-anatomiche come chiave esemplificativa del gesto chirurgico. Verrà spegata ed attuata dal vivo in live-surgery la preparazione […]. ...
Hydrocortisone + zinc oxide + lidocaine + allantoin is used in the treatment of .get complete information about hydrocortisone + zinc oxide + lidocaine + allantoin including usage, side effects, drug interaction, expert advice along with medicines associated with hydrocortisone + zinc oxide + lidocaine + allantoin at 1mg.com
By Nutri People. Allantoin is a particular active part of the herb comfrey (Symphytum officinale). Allantoin is popular for skincare, as it is well absorbed, helps soothe and is easily dispersed throughout the body. It supports the renewal of healthy collagen, especially in skin, and helps tone, moisturise and soften skin.. ...
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the anaerobic utilization of allantoin as sole nitrogen source. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate.
Man Look After Shave Balsam With Allantoin - Anti Razor Pumps - 125gm price from jumia in Egypt. Compare prices and shop online now.
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as secondary nitrogen source when primary sources are limiting.
Urea Amidolyase; Contains Both Urea Carboxylase And Allophanate Hydrolase Activities, Degrades Urea To CO2 And NH3; Expression Sensitive To Nitrogen Catabolite Repression And Induced By Allophanate, An Intermediate In Allantoin Degradation; Protein Abundance Increases In Response To DNA Replication Stress
Uric acid is by-far the highest concentration antioxidant in human blood. Uric acid (UA) is an antioxidant oxypurine produced from xanthine by the enzyme xanthine oxidase, and is an intermediate product of purine metabolism. In almost all land animals, urate oxidase further catalyzes the oxidation of uric acid to allantoin,but in humans and most higher primates, the urate oxidase gene is nonfunctional, so that UA is not further broken down.The evolutionary reasons for this loss of urate converstion to allantoin remain the topic of active speculation. The antioxidant effects of uric acid have led researchers to suggest this mutation was beneficial to early primates and humans.Studies of high altitude acclimatization support the hypothesis that urate acts as an antioxidant by mitigating the oxidative stress caused by high-altitude hypoxia.In animal studies that investigate diseases facilitated by oxidative stress, introduction of UA both prevents the disease or reduces it, leading researchers to ...
Imidazole, appears in a number of pharmaceuticals, is characterized by a ring structure composed of three carbon atoms and two nitrogen atoms at nonadjacent positions. The simplest member of the imidazole family is itself, a compound with molecular formula C3H4N2. Labs can produce it and its derivatives, like clotrimazole and econazole, synthetically. This allows for efficient mass production in a controlled environment.. The chemical was first prepared in 1858. Other imidazole compounds have been known longer: allantoin (discovered in 1800) and parabanic acid were prepared in 1837 from uric acid. The amino acid histidine and its decomposition product histamine have the structure, as does biotin, a growth factor for both humans and yeast.. Patients may be told to take an imidazole to treat a fungal infection because it has a broad mechanism of action and is usually easy to use. It can be applied topically to skin infections as well as fungal infections in the eyes and orifices, like vaginal ...
Dermaheal Post Laser Cream information about active ingredients, pharmaceutical forms and doses by EIG Pharma, Dermaheal Post Laser Cream indications, usages and related health products lists
Elastin Collagen is an advanced firming nourish lotion suitable for all skin types concerned with anti-aging. A non-greasy, lightweight moisturizer with Elastin & Collagen to firm, improve elasticity and restore skin suppleness. Squalane, derived from olives, is a natural nourishment to parched skin. Allantoin is a natural botanical extract used to promote healthy skin renewal effects. Ingredients: AQUA (WATER), ISOCETYL STEARATE, BUTYLENE GLYCOL, GLYCERIN, ROSE WATER CONCENTRATE, CETYL ALCOHOL, STEARIC ACID, STEARYL ALCOHOL, GLYCERYL STEARATE, HYDROLYZED COLLAGEN, HYDROLYZED ELASTIN, SODIUM LAURYL SULFATE, TRIETHANOLAMINE, SQUALANE OIL, 3-AMINOPROPYL DIHYDROGEN PHOSPHATE, ALLANTOIN, LACTIC ACID, PHENOXYETHANOL, ETHYLHEXYLGLYCERIN
These include ammonia, allantoin, uric acid, and urea. Arthropod hormones are present most notably the juvenile hormone. ...
Van der Drift L, Vogels GD, Van der Drift C (1975). "Allantoin racemase: a new enzyme from Pseudomonas species". Biochim. ...
Similarly to rasburicase, it metabolises uric acid to allantoin. This reduces the risk of precipitates, since allantoin is five ...
For this purpose, it is sometimes combined with allantoin. It binds to the hair shaft readily; so, it is a common component of ...
... can also be synthesized either by heating allantoin with hydroiodic acid or by "heating bromacetyl urea with ... He obtained it by hydrogenation of allantoin, hence the name. Friedrich Urech synthesized 5-methylhydantoin in 1873 from ...
When heated with urea to 100 °C, it forms allantoin. By continued boiling of its aqueous solution it is decomposed into carbon ...
It is a crystalline acid obtained by hydrolysis of allantoin. "allantoic acid - Compound Summary". PubChem Compound. USA: ...
In enzymology, an allantoinase (EC 3.5.2.5) is an enzyme that catalyzes the chemical reaction (S)-allantoin + H2O ⇌ {\ ... The systematic name of this enzyme class is (S)-allantoin amidohydrolase. This enzyme participates in purine metabolism. ... displaystyle \rightleftharpoons } allantoate Thus, the two substrates of this enzyme are (S)-allantoin and H2O, whereas its ...
It is the third step of the conversion of uric acid (a purine derivative) to allantoin. Step one is catalysed by urate oxidase ... Kim K, Park J, Rhee S (2007). "Structural and functional basis for (S)-allantoin formation in the ureide pathway". J Biol Chem ... It catalyses the decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) into S(+)-allantoin. ...
This is converted to 5-hydroxyisourate, which decarboxylates to allantoin and allantoic acid. After hydrolyzing one urea, this ...
The active chemical constituents are aucubin (an anti-microbial agent), allantoin (which stimulates cellular growth and tissue ... It contains many bioactive compounds, including allantoin, aucubin, ursolic acid, flavonoids, and asperuloside. Scientific ... the cell-growth promoter allantoin, a large amount of soothing mucilage, flavonoids, caffeic acid derivatives, and alcohols in ...
... resulting in decreased conversion to allantoin, so this breed excretes uric acid, and not allantoin, in the urine. In birds and ... In most other mammals, the enzyme uricase further oxidizes uric acid to allantoin. The loss of uricase in higher primates ...
Allantoin Formylmethionine Methionine oxidation Paracetamol poisoning - A Methionine-Paracetamol preparation that might prevent ...
The name is derived from allantoin, a product of uric acid excreted by the fetus into the allantois, and oxaluric acid derived ... The name "Alloxan" emerged from an amalgamation of the words "allantoin" and "Oxalsäure" (oxalic acid). The alloxan model of ...
His research included studies of nitrites, allantoin, aromatic glycols and on the synthesis of citric acid. Also, he conducted ...
It is a recombinant version of urate oxidase, an enzyme that metabolizes uric acid to allantoin. Urate oxidase is known to be ... Rasburicase catalyzes enzymatic oxidation of poorly soluble uric acid into an inactive and more soluble metabolite allantoin ...
Supplemental use of an anti-irritant such as allantoin may also be helpful in reducing irritation. At higher concentrations (10 ...
... is only able to grow in the presence of uric acid, allantoin, or allantoic acid. Bacillus fastidiosus has ... Bacillus fastidious has the ability to use uricase to degrade uric acid to allantoin, and then use allantoinase to degrade ... allantoin to allantoate. It also has the ability to further break down allantoate to ammonia and ureidoglycolate via the enzyme ...
... and allantoin. While cytostatic agents such as zinc pyrithione are first line, keratolytics (salicylic acid and sulfur) can ...
Maggots secrete several chemicals that kill microbes, including allantoin, urea, phenylacetic acid, phenylacetaldehyde, calcium ...
Water (purified), PEG-4, Aloe barbadensis leaf juice, Allium cepa (onion) bulb extract, xanthan gum, allantoin, methylparaben, ... allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized ...
The plant contains the small organic molecule allantoin, which is thought to stimulate cell growth and repair while also ...
... is produced by the chemical reaction of allantoin and formaldehyde in the presence of sodium hydroxide ...
In 1960, Sunsilk Tonic shampoo was launched, containing skin healing ingredient Allantoin - designed to help keep the scalp ...
... is a component of some skin care products together with other skin soothing compounds such as allantoin. Guaiazulene has ...
Allantoin acts as an astringent to cause the cells that it comes into contact with to shrink and dry out. This causes shrinkage ... Anodesyn (allantoin, lidocaine). Anodesyn ointment and suppositories contain lidocaine hydrochloride (previously known as ... There are currently no other medicines available in the UK that contain allantoin and lidocaine as the active ingredients. ...
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
ARC SKIN PROTECTANT (allantoin) ointment. NDC Code(s): 69148-001-00, 69148-001-01 *Packager: Anjon Biologics, Inc ... ANY MI NATURAL MAGIC BB NO.5 (allantoin) cream. NDC Code(s): 62695-1001-1 *Packager: K.N.Life Co., Ltd. ... ANY MI NATURAL MAGIC BB NO.7 (allantoin) cream. NDC Code(s): 62695-2001-1 *Packager: K.N.Life Co., Ltd. ... ATOMU (allantoin) cream. NDC Code(s): 72544-030-01, 72544-030-02 *Packager: CELIM BIOTECH CO.,LTD ...
14C Allantoin passed through the blood bicarbonate pool, suggesting that Allantoin is degraded in the gastrointestinal tract. A ... Test animals were dosed with 28 µCi of 4,5-14C labeled Allantoin and 15 mg unlabelled Allantoin in 10 mL isotonic saline via ... Uric acid is converted to Allantoin by urate oxidase, followed by Allantoin excretion. Humans and some non-human primates do ... Most mammals process purines to Allantoin yielding stable endogenous levels of Allantoin in both blood and urine. Purine ...
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
Allantoin is an excellent addition to handmade facial toners, lotions, creams, and even mineral makeup. ... Allantoin is an excellent addition to the most luxurious of handmade products. This powder can be added to nearly any water ... Allantoin Powder: Allantoin Powder is an excellent addition to the most luxurious of handmade products. It can be added to ... I use Allantoin in my facial creams. So Im glad to see that Bramble Berry is now offering this item. A little goes a long way ...
ALLANTOIN (UNII: 344S277G0Z) (ALLANTOIN - UNII:344S277G0Z). ALLANTOIN. 0.425 g in 85 g. ... ALLANTOIN- advanced derma spray aerosol, spray To receive this label RSS feed. Copy the URL below and paste it into your RSS ... ALLANTOIN- advanced derma spray aerosol, spray Out of scope - Out of scope for RxNorm and will not receive RxNorm normal forms ...
... allantoin Hence, this enzyme has one substrate, (S)(+)-allantoin, and one product, (R)(-)-allantoin. This enzyme belongs to the ... In enzymology, an allantoin racemase (EC 5.1.99.3) is an enzyme that catalyzes the chemical reaction (S)(+)-allantoin ⇌ {\ ... The systematic name of this enzyme class is allantoin racemase. This enzyme participates in purine metabolism. Van der Drift L ... Vogels GD, Van der Drift C (1975). "Allantoin racemase: a new enzyme from Pseudomonas species". Biochim. Biophys. Acta. 391 (1 ...
Find user ratings and reviews for lanolin-allantoin topical on WebMD including side effects and drug interactions, medication ... Read user comments about the side effects, benefits, and effectiveness of lanolin-allantoin topical. ...
Allantoin is used as a moisturizing agent to prevent or treat various skin disorders such as dry, itchy, scaly skin or the ... General Information on Allantoin. Generic Name : Allantoin Pronunciation : al-lan- to-in. Latest prescription information about ... Why is Allantoin Prescribed? (Indications) Allantoin is used as a moisturizing agent to prevent or treat various skin disorders ... Trade Names/Brand Names of Allantoin. India : Anomex , Prucial , Aloederm-B (250 gm) , Cosglo , Masse Cream , Alorex , Alphosyl ...
Alphosyl Lotion information about active ingredients, pharmaceutical forms and doses by GlaxoSmithKline, Alphosyl Lotion indications, usages and related health products lists
Silco information about active ingredients, pharmaceutical forms and doses by Candor Biotech, Silco indications, usages and related health products lists
If allantoin is proven to also increase longevity in humans, the next step would be turning it into a pill. The worms ingested ... The next step for us is to understand the mechanisms by which allantoin extends life span, as this could reveal new longevity ... A team of researchers at the University of Liverpool has discovered that allantoin, an ingredient found in many skin-care ... When the researchers tested the effects of allantoin-a botanical extract derived from the comfrey plant-on nematode worms, they ...
... and Allantoin 2.5% Cream. Includes ingredients, method of preparation, discussion, and references for the compounding ... Coal Tar 2% and Allantoin 2.5% Cream. Allen Loyd V Jr Nov/Dec 2007. 508. Buy. ... Related Keywords: Loyd V. Allen, Jr., PhD, RPh, formulation, skin disorders, coal tar, allantoin, antiseptic agent, astringent ... Abstract: A formulation for preparing Coal Tar 2% and Allantoin 2.5% Cream. Includes ingredients, method of preparation, ...
Allantoin, Allantoin Ascorbate, Allantoin Biotin, Allantoin Galacturonic Acid, Allantoin Polygalacturonic Acid, Allantoin ... Allantoin Biotin, Allantoin Galacturonic Acid, Allantoin Polygalacturonic Acid, Allantoin Glycyrrhetinic Acid and Allantoin ... Allantoin Biotin, Allantoin Galacturonic Acid, Allantoin Polygalacturonic Acid, Allantoin Glycyrrhetinic Acid and Allantoin ... Allantoin Ascorbate, and the Allantoin salt of vitamin B7, Allantoin Biotin. Allantoin complexes that may be used in cosmetics ...
Nutrient - Allantoin. By Nutri People. Allantoin is a particular active part of the herb comfrey (Symphytum officinale). ... Allantoin is popular for skincare, as it is well absorbed, helps soothe and is easily dispersed throughout the body. It ...
C, Michaelis-Menten kinetics of [14C]allantoin uptake. D, Inhibition of [14C]allantoin uptake in yeast cells. [14C]allantoin ... Synthesis and Purification of [14C]Allantoin for Transport Studies. [14C]allantoin was produced from 8-[14C]uric acid in a ... 5J), suggesting a role of PvUPS1 in importing allantoin into the symplast to pass the endodermis and in loading of allantoin ... Transport studies in yeast cells with [14C]-labeled allantoin showed that PvUPS1 mediates uptake of allantoin (Fig. 3A) and ...
F). To completely mix and disperse Allantoin, very good mixing is a must.. INCI: Allantoin. Country of origin: Could be U.S., ... This chemically synthesized allantoin, which is chemically equivalent to natural allantoin, is non-toxic and compatible with ... Synthetic allantoin is available today to accelerate wound healing and is used for skin ulcer therapy when applied topically ( ... Allantoin is used in cosmetic applications such as shaving creams, shampoos, lipsticks, suntan products, hair gels, body powder ...
But back to allantoins role in skin care. Allantoin is a white, odorless powder that is safe and non-allergenic. Its properties ... Humans however, do not have this enzyme and so do not make allantoin, or at least not significant amounts. Allantoin will ... How does Colorado Aromatics use allantoin? In three of our balms we use allantoin containing herbs; comfrey in our Joint Jam ... Allantoin is formed from uric acid which occurs from breakdown of purine. I love when my current reading takes me back to ...
In this regard, allantoin is sometimes used as a marker of oxidative stress. Allantoin can be isolated from cow urine or as a ... Allantoin. Description. Allantoin is a diureide of glyoxylic acid with the chemical formula C4H6N4O3. It is also called 5- ... Allantoin helps to heal wounds and skin irritations and stimulates the growth of healthy tissue. Allantoin can be found in anti ... In humans, uric acid is excreted instead of allantoin. The presence of allantoin in the urine can be an indication of microbial ...
Allantoin Market size is set to exceed USD 670 million by 2023 led by increasing demand from cosmetic sector says, a new ... Allantoin Market size is set to exceed USD 670 million by 2023; according to a new research report by Global Market Insights, ... Allantoin market research report includes in-depth coverage of the industry with estimates & forecast in terms of volume in ... Allantoin Market worth over USD 670 million by 2023. Published Date: February 3, 2017 Author: Global Market Insights, Inc. ...
... containing onion extract and allantoin has been developed for preventing and treating dermatologic scars and keloids. Here, we ... Ho WS, Ying SY, Chan PC, Chan HH (2006) Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese ... Our results agree with other studies showing that the onion extract and allantoin used in the OIP are effective and well ... This study examined an OIP that combines the benefits of occlusion and onion extract and allantoin. The study confirmed that ...
... Hellsten, Y ... During EX1 there was a significant accumulation of urate (from 0.16 +/- 0.02 to 0.27 +/- 0.03 micromol/kg d.w.) and allantoin ( ... yet the level of oxidative stress in EX1 and EX2 was similar as evidenced by a similar increase in muscle allantoin in both ...
Acnoff (Allantoin) Drug Price and Information. Allantoin is used as a moisturizing agent to prevent or treat various skin ...
Allantoin) drug information & product resources from MPR including dosage information, educational materials, & patient ...
  • Read user comments about the side effects, benefits, and effectiveness of lanolin-allantoin topical. (webmd.com)
  • Allantoin has been widely used for decades in cosmetic and OTC topical formulations because it is so effective at only 0.5%, making it an economical anti-inflammatory additive. (ingredientstodiefor.com)
  • Allantoin is also used in the topical pharmaceutical market in psoriasis medications and analgesic gels. (ingredientstodiefor.com)
  • A study shows that topical application of allantoin, along with other ingredients, improves skin texture and drastically reduces the appearance of wrinkles and fine lines ( 4 ). (stylecraze.com)
  • The FDA-approved topical application of allantoin at 0.5% to 2.0% concentration is considered safe ( 1 ). (stylecraze.com)
  • Allantoin, also known as glyoxyldiureide or 5-ureidohydantoin, belongs to the class of organic compounds known as imidazoles. (ymdb.ca)
  • Allantoin will however, accumulate in times of oxidative stress and is a marker for that. (sagescript.com)
  • In this regard, allantoin is sometimes used as a marker of oxidative stress. (hmdb.ca)
  • 05). The glycogen levels were lowered by 40% at the onset of EX2, yet the level of oxidative stress in EX1 and EX2 was similar as evidenced by a similar increase in muscle allantoin in both exercise bouts. (diva-portal.org)
  • This might indicate that progeny from plates have better ROS protection, while liquid culture progeny are more susceptible to oxidative stress and uric acid acts there as an endogenous antioxidant, resulting in its nonenzymatic oxidation to allantoin. (wormbook.org)
  • Overall, these experiments suggest that different levels of oxidative stress may not explain differences in the uric acid/allantoin ratio. (wormbook.org)
  • It turns out that urate can spontaneously oxidize to form allantoin, and some think that this is an indicator of oxidative stress (whatever that means in this context). (nilssonlab.se)
  • To address this issue we evaluated the relationship between procedural pain, ATP utilization (hypoxanthine and uric acid), and oxidative stress (MDA and allantoin) in premature infants. (llu.edu)
  • Based upon these data, we recommend conducting age-matched as well as weight for age-matched studies when using urinary purines and allantoin to evaluate the relationship between procedural pain and hypoxia on ATP utilization and oxidative stress. (llu.edu)
  • When the researchers tested the effects of allantoin-a botanical extract derived from the comfrey plant-on nematode worms, they found that it mimicked the calorie-restriction process and increased the life span of the worms by 20 percent. (allure.com)
  • Allantoin can be isolated from cow urine or as a botanical extract of the comfrey plant. (hmdb.ca)
  • An occlusive overnight intensive patch medical device (OIP) containing onion extract and allantoin has been developed for preventing and treating dermatologic scars and keloids. (springer.com)
  • An occlusive overnight intensive patch medical device (OIP) containing onion extract and allantoin was recently developed to provide optimal scar healing and improved convenience for the patient. (springer.com)
  • A popular source of allantoin is the extract of comfrey, a species of herb native to Europe. (beautycarechoices.com)
  • Fortified with Licorice Extract and Allantoin to help soothe. (dermalogica.com)
  • Chemically synthesized allantoin is frequently present in toothpaste, mouthwash and other oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products and clarifying lotions, various cosmetic lotions and creams and other cosmetic and pharmaceutical products. (camdengrey.com)
  • Increasing product usage in the cosmetic sector was the prime factor propelling the overall allantoin market size over the estimated period. (gminsights.com)
  • When 0.5% to 2.0% Allantoin is added to cosmetic and personal care products and no claims are made related to Allantoin, the product remains a cosmetic . (ingredientstodiefor.com)
  • Allantoin can be used in cosmetic and personal care products AS LONG AS NO CLAIM ARE MADE related to skin protection. (thebeautybrains.com)
  • Moreover, the use of synthetically produced allantoin has received GRAS status from U.S. Food and Drug Administration for its recommended use in the cosmetic and personal care products. (transparencymarketresearch.com)
  • Excretion of orally dosed Allantoin is approximately 30% of the absorbed dose in rats and humans and 75% of the absorbed dose in canines. (europa.eu)
  • If allantoin is proven to also increase longevity in humans, the next step would be turning it into a pill. (allure.com)
  • The dermal penetration of Allantoin in humans was shown to be dependent on the formulation. (cosmeticsinfo.org)
  • Humans however, do not have this enzyme and so do not make allantoin, or at least not significant amounts. (sagescript.com)
  • In humans, uric acid is excreted instead of allantoin. (hmdb.ca)
  • Allantoin exists in all living species, ranging from bacteria to humans. (ymdb.ca)
  • A putative allantoin transporter ( PvUPS1 ) was isolated from nodulated roots of French bean and was functionally characterized in an allantoin transport-deficient yeast mutant showing that PvUPS1 transports allantoin but also binds its precursors xanthine and uric acid. (plantphysiol.org)
  • Next, we examined clinical factors that need to be considered when using the urinary concentrations of hypoxanthine, xanthine, uric acid, and allantoin to evaluate the biochemical effects of procedural pain. (llu.edu)
  • While allantoin is present in botanical extracts of the comfrey plant, it is generally chemically synthesized to meet worldwide demand. (lotioncrafter.com)
  • Sometimes allantoin is naturally-derived from the leaves and roots of the comfrey plant (or other such plants). (skincarevibes.com)
  • Known for its moisturizing, protecting and healing qualities, allantoin is found naturally in the comfrey plant, which has been used for centuries as a natural soothing and healing source. (votrevu.com)
  • Allantoin is a naturally occurring compound that can be derived from the comfrey plant or from mammal urine. (thebeautybrains.com)
  • Allantoin is a compound found in the root of the comfrey plant, a hairy perennial Eurasian herb long used in herbal medicine. (kiehls.com)
  • In tropical legumes like French bean ( Phaseolus vulgaris ) or soybean ( Glycine max ), most of the fixed nitrogen is used for synthesis of the ureides allantoin and allantoic acid, the major long-distance transport forms of organic nitrogen in these species. (plantphysiol.org)
  • Excretion of intravenously or subcutaneously dosed Allantoin approaches quantitative levels regardless of species. (europa.eu)
  • Allantoin distribution in blood and urine is discussed more fully in the context of absorption and excretion. (europa.eu)
  • However, distribution has been evaluated in the rumen of sheep and in the fetus of pregnant rhesus monkeys, further supporting the rapid absorption and excretion of Allantoin. (europa.eu)
  • Urinary Allantoin Excretion as a Marker of Microbial Crude Protein Sup" by Ryan Mass, D. J. Jordon et al. (unl.edu)
  • Two metabolism trials evaluated urinary allantoin excretion as a noninvasive marker of microbial crude protein flow from the rumen. (unl.edu)
  • In the first trial, both urinary allantoin excretion and duodenal purine flow increased as alfalfa intake increased. (unl.edu)
  • In the second trial, an increase in the metabolizable energy supplied to the animal did not increase urinary allantoin excretion. (unl.edu)
  • We concluded that urinary allantoin excretion was an effective, noninvasive marker of microbial crude protein supply. (unl.edu)
  • The overall allantoin market share for pharmaceutical shall witness maximum growth more than 6% by 2023. (gminsights.com)
  • Moreover, rising scope of applications of allantoin in the pharmaceutical products, such as eye drops and skin care creams, is also expected to drive the market growth during the forecast period. (express-press-release.net)
  • Allantoin also has been described as a cell proliferant, an epithelization stimulant and a chemical debrider in texts such as the United States Dispensatory, Merck Index, and British Pharmaceutical Codex. (ingredientstodiefor.com)
  • The DAL80 locus has been located and is not linked to any of the structural genes of the allantoin pathway. (asm.org)
  • The allantoin-degradative pathway of Saccharomyces cerevisiae consists of several genes whose expression is highly induced by the presence of allophanic acid. (asm.org)
  • A method for increasing the stability and solubility of allantoin in hydroalcoholic solutions, which comprises combining allantoin with hydrolyzed animal protein to form the product as defined in claim 1. (lens.org)
  • Allantoin, which is a component of many plants including comfrey, has been reported to provide healing, soothing, and anti-irritating properties and to help to heal wounds and skin irritations and stimulate growth of healthy tissue. (cosmeticsinfo.org)
  • In fact, at one time blowfly larvae were used to treat severe wounds because of its high content of allantoin. (sagescript.com)
  • Allantoin can be found in anti-acne products, sun care products, and clarifying lotions because of its ability to help heal minor wounds and promote healthy skin. (hmdb.ca)
  • Allantoin helps heal wounds, skin injuries, and scars faster. (stylecraze.com)
  • Because Allantoin is rapidly absorbed and excreted, distribution in tissues and fluids other than blood and urine has not been extensively studied. (europa.eu)
  • Approximately 80% of the 14C Allantoin was recovered in the urine during the 12 hr. immediately post injection. (europa.eu)
  • Technically, allantoin can also be isolated from animal urine. (skincarevibes.com)
  • Isolation and characterization of mutants that produce the allantoin-degrading enzymes constitutively in Saccharomyces cerevisiae. (asm.org)
  • A gene product needed for induction of allantoin system genes in Saccharomyces cerevisiae but not for their transcriptional activation. (asm.org)
  • From these observations we conclude that production of the allantoin-degrading enzymes is regulated by the DAL80 gene product and that induction and repression of enzyme synthesis can be cleanly separated mutationally. (asm.org)
  • After transport to neighboring uninfected cells, uric acid is used for allantoin synthesis in peroxisomes. (plantcell.org)
  • Allantoin is a superior humectant, which means it draws moisture from the air to the skin. (brambleberry.com)
  • Allantoin is used as a moisturizing agent to prevent or treat various skin disorders such as dry, itchy, scaly skin or the psoriasis symptoms and for specific skin irritations such as minor burns due to radiotherapy or a diaper rash. (medindia.net)
  • Allantoin, Allantoin Ascorbate, Allantoin Biotin, Allantoin Galacturonic Acid, Allantoin Polygalacturonic Acid, Allantoin Glycyrrhetinic Acid and Allanotin Panthenol all function as skin-conditioning agents - miscellaneous. (cosmeticsinfo.org)
  • Allantoin also functions as a skin protectant . (cosmeticsinfo.org)
  • Allantoin was not an eye or skin irritant and it was not phototoxic. (cosmeticsinfo.org)
  • The other compounds containing Allantoin all function as skin conditioning agents - miscellaneous. (cosmeticsinfo.org)
  • Synthetic allantoin is available today to accelerate wound healing and is used for skin ulcer therapy when applied topically (also used in veterinary medicine). (camdengrey.com)
  • Allantoin enhances desquamation of dead upper layers of skin meaning that it promotes exfoliation and thus improves the smoothness of skin. (sagescript.com)
  • But back to allantoins role in skin care. (sagescript.com)
  • In our higher end products we use pure allantoin in our Springtide Antiaging Cream for its skin regeneration properties and antiaging properties and in our Oasis Spray Lotion for its anti-irritant properties. (sagescript.com)
  • Allantoin™ is a skin protectant for use in creams, lotions, lip products, shaving creams, suntan products and baby products. (chempoint.com)
  • Allantoin is used as a medicated moisturiser which prevents or treats dry, rough, scaly, skin and minor skin irritations such as skin burns , diaper rash , from radiation therapy. (lybrate.com)
  • A stable form of allantoin is provided which takes the form of a combined allantoin-hydrolyzed animal protein product which may be employed in the form of a hydroalcoholic solution, such as a cologne, after-shave lotion or skin toner, containing at least about 0.5% by weight allantoin which remains in solution, without crystallizing out, over extended periods of time. (lens.org)
  • Allantoin produces its desirable effects by promoting healthy skin. (ingredientstodiefor.com)
  • Allantoin helps alleviate and prevent symptoms of irritated and dry skin, and dry / chapped lips. (ingredientstodiefor.com)
  • The U.S. Food and Drug Administration in the Tentative Monograph, 48 Federal Register 6820-33 defines Allantoin as a skin protectant. (ingredientstodiefor.com)
  • Allantoin fuctions as a skin protectant and conditioning agent in skincare products, making skin appear more supple and reducing the appearance of damaged skin, according to CosmeticsInfo.org. (livestrong.com)
  • Allantoin in Skin Care: Benefits & More! (skincarevibes.com)
  • Studies have shown that treatments containing allantoin aren't as good as more modern treatments when considering psoriasis (a condition characterized by scaly skin) ( source 1 , source 2 ). (skincarevibes.com)
  • Allantoin: What Is It And What Are The Skin Benefits? (stylecraze.com)
  • So, without further ado, let's check out what exactly allantoin does to your skin. (stylecraze.com)
  • The allantoin developed in laboratories is just as potent as its naturally-occurring counterpart, and it can help your skin in many ways. (stylecraze.com)
  • Allantoin keeps your skin hydrated by preventing transepidermal water loss ( 4 ). (stylecraze.com)
  • If you have dry and flaky skin, allantoin can help it retain more water and keep it moisturized ( 5 ). (stylecraze.com)
  • Allantoin works as a conditioning agent for your skin. (stylecraze.com)
  • If you use any skin product with allantoin and experience any of these side effects, stop using it immediately and consult a doctor. (stylecraze.com)
  • Want to try out allantoin on your skin? (stylecraze.com)
  • Check out the list of the best allantoin-based skin care products available on the market. (stylecraze.com)
  • While lanolin's texture is waxy, gummy and thick, allantoin feels slippery and moist against the skin. (oureverydaylife.com)
  • Given it's ability to prevent AND treat skin irritation, I'd say Allantoin is probably responsible for the Anti-Howdy Doody effect. (thebeautybrains.com)
  • Derived from comfrey root, allantoin is a natural anti-irritant with soothing and healing properties that aids in the healing of damaged skin by stimulating new tissue growth. (afterglowcosmetics.com)
  • Within our formulas, Allantoin is known to soothe and comfort skin. (kiehls.com)
  • Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring. (uniprot.org)
  • By functional complementation of a yeast mutant defective in allantoin uptake, an Arabidopsis transporter, AtUPS1 ( Arabidopsis thaliana ureide permease 1 ), was identified. (plantcell.org)
  • and its oxidation can proceed nonenzymatically, e.g., in the presence of ROS, with allantoin being one of the oxidation products. (wormbook.org)
  • This type of allantoin won't likely end up in your skincare products-it's just so much easier (and cheaper) to produce it synthetically. (skincarevibes.com)
  • But according to Drugbank, allantoin is commonly found in moisturizing creams & lotions, dental products (i.e. toothpastes and mouthwashes), shaving creams, sun care products, lipsticks, aerosols (i.e. hairsprays), and anti-acne products ( source ). (skincarevibes.com)
  • Any products that contain an active level of Allantoin could be worth a try. (thebeautybrains.com)
  • It is postulated that Allantoin cleanses away necrotic tissue, speeding up the growth of new, healthy tissue. (ingredientstodiefor.com)
  • This fact has spawned a fairly common misconception that allantoin is made from the fetal tissue or placenta. (oureverydaylife.com)
  • Il falicite le processus de récupération de la peau en évitant la formation excessive de tissue cicatriciel de l'intérieur. (freerxacc.com)
  • Allantoin is also found in many plants, such as comfrey, horse chestnut and bearberry. (cosmeticsinfo.org)
  • When comparing exo-metaboloms of arrested L1s (L1 medium) whose parents were grown on bacterial plates vs. liquid bacterial culture we found that progeny of worms grown in liquid produce substantially more allantoin and less uric acid than progeny of worms from plates (Fig. 2). (wormbook.org)
  • We then compared uric acid and allantoin levels in L1 medium of sod-3 ( tm760 ) , sod-5 ( tm1146 ) and N2 whose parents were grown on plates and found no significant difference. (wormbook.org)
  • In conclusion, we found that in arrested L1 worms whose parents were grown on plates purine metabolism stops at uric acid, while in arrested L1s whose parents were grown in liquid culture it proceeds one step further and uric acid is converted to allantoin. (wormbook.org)
  • In fact, a study conducted in 2010 found that injured rats treated with a 5% allantoin-based emulsion healed faster than rats not treated with allantoin ( source ). (skincarevibes.com)
  • Allantoin is also found in sugar beets, chamomile, and wheat sprouts, but not as abundantly as in comfrey. (stylecraze.com)
  • While allantoin is produced artificially and found in hundreds of natural sources, lanolin can only be extracted from a single source: sheep's wool. (oureverydaylife.com)
  • In nature, allantoin can be found in the placental tissues of many mammals. (oureverydaylife.com)
  • Allantoin was also found to be significantly altered by gestational age. (llu.edu)
  • We found a total of 117 words by unscrambling the letters in allantoin. (allscrabblewords.com)
  • We noted while "pinning metabolites" that allantoin was present in the mass spec data from UCSD. (nilssonlab.se)
  • In a study of limited reliability due to the small number of human test subjects (n=6), Allantoin (1%) doses were prepared in both hydrophilic gel and oil/water emulsion vehicles. (europa.eu)
  • Make your emulsion, then add Allantoin during the cooling process (the emulsion should be below 90 deg. (camdengrey.com)
  • To incorporate 0.5% Allantoin, or more, into an emulsion product, the emulsion is made and Allantoin is added during the cooling process below 50°C (122°F). Good agitation is required to thoroughly disperse the Allantoin to achieve a suitable suspension. (lotioncrafter.com)
  • When purines do breakdown (instead of being salvaged) they form uric acid which in most organisms is converted to allantoin by the enzyme uricase. (sagescript.com)
  • Specifically, we determined the effects of gestational age, weight for gestational age, and neonatal morbidity on the urinary concentration of purines and allantoin. (llu.edu)
  • In addition, respiratory morbidity significantly increased urinary purines, but not allantoin, within the late preterm population. (llu.edu)
  • Although no data were identified on the compounds containing Allantoin, the CIR Expert Panel has previously reviewed the safety of ascorbic acid, biotin, glycyrrhetinic acid and panthenol. (cosmeticsinfo.org)