Allantoin
Urate Oxidase
Urea
Racemases and Epimerases
Uric Acid
Membrane Transport Modulators
Amidine-Lyases
Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. (1/150)
Members of the BMP family of signaling molecules display a high conservation of structure and function, and multiple BMPs are often coexpressed in a variety of tissues during development. Moreover, distinct BMP ligands are capable of activating common pathways. Here we describe the coexpression of two members of the 60A subfamily of BMPs, Bmp5 and Bmp7, at a number of different sites in the embryo from gastrulation onwards. Previous studies demonstrate that loss of either Bmp5 or Bmp7 has negligible effects on development, suggesting these molecules functionally compensate for each other at early stages of embryonic development. Here we show this is indeed the case. Thus we find that Bmp5;Bmp7 double mutants die at 10.5 dpc and display striking defects primarily affecting the tissues where these factors are coexpressed. The present analysis also uncovers novel roles for BMP signaling during the development of the allantois, heart, branchial arches, somites and forebrain. Bmp5 and Bmp7 do not appear to be involved in establishing pattern in these tissues, but are instead necessary for the proliferation and maintenance of specific cell populations. These findings are discussed with respect to potential mechanisms underlying cooperative signaling by multiple members of the TGF-beta superfamily. (+info)Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. (2/150)
A large body of experimental evidence supports the participation of two groups of extracellular proteases, matrix metalloproteinases (MMPs), and plasminogen activators/plasmin, in tissue remodeling in physiological and pathological invasion. In the late mouse placenta, several tissue remodeling and cell invasion processes take place. Spongiotrophoblast migration into maternal decidua, as well as decidual extracellular matrix remodeling require the coordinated action of extracellular proteolytic enzymes. Via Northern and in situ hybridization, we have analyzed the spatio-temporal expression patterns of members of the MMP family (stromelysin-3, gelatinases A and B), as well as their inhibitors TIMP-1, -2 and -3 in late murine placenta (days 10.5 to 18.5 of gestation). Gelatinase activity in placental extracts was assessed by substrate zymography. Gelatinase A and stromelysin-3 were found to be prominently expressed in decidual tissue; shortly after midpregnancy, the decidual expression patterns of gelatinase A and stromelysin-3 became overlapping with each other, as well as with the expression domain of TIMP-2. On the other hand, gelatinase B transcripts were expressed only by trophoblast giant cells at day 10.5, and were downregulated at later stages. TIMP-1 and TIMP-3 transcripts were detected in decidual periphery at day 10.5, while later the expression was restricted to the endometrial stroma and spongiotrophoblasts, respectively. The areas of stromelysin-3 expression were the same (giant trophoblasts) or adjacent (decidua) to those where urokinase (uPA) transcripts were detected, suggesting a possible cooperation between these proteinases in placental remodeling. We generated mice doubly deficient for stromelysin-3 and uPA, and report here that these mice are viable and fertile. Furthermore, these animals do not manifest obvious placental abnormalities, thereby suggesting the existence of compensatory/redundant mechanisms involving other proteolytic enzymes. Our findings document the participation of MMPs and their inhibitors in the process of late murine placenta maturation, and warrant the characterization of other members of the MMP family, like membrane type-MMPs, in this process. (+info)Investigation of cell culture media infected with viruses by pyrolysis mass spectrometry: implications for bioaerosol detection. (3/150)
Mass spectrometry coupled with a pyrolysis inlet system was used to investigate media from cell cultures infected with viruses. Cell culture media is an intricate mixture of numerous chemical constituents and cells that collectively produce complicated mass spectra. Cholesterol and free fatty acids were identified and attributed to lipid sources in the media (blood serum supplement and plasma membranes of host cells). These lipid moieties could be utilized as signature markers for rapidly detecting the cell culture media. Viruses are intracellular parasites and are dependent upon host cells in order to exist. Therefore, it is highly probable that significant quantities of media needed to grow and maintain viable host cells would be present if a viral agent were disseminated as an aerosol into the environment. Cholesterol was also detected from a purified virus sample, further substantiating its use as a target compound for detection. Implications of this research for detection of viral bioaerosols, using a field-portable pyrolysis mass spectrometer, is described. (+info)Overlapping positive and negative GATA factor binding sites mediate inducible DAL7 gene expression in Saccharomyces cerevisiae. (4/150)
Allantoin pathway gene expression in Saccharomyces cerevisiae responds to two different environmental stimuli. The expression of these genes is induced in the presence of allantoin or its degradative metabolites and repressed when a good nitrogen source (e. g. asparagine or glutamine) is provided. Three types of cis-acting sites and trans-acting factors are required for allantoin pathway gene transcription as follows: (i) UAS(NTR) element associated with the transcriptional activators Gln3p and Gat1p, (ii) URS(GATA) element associated with the repressor Dal80p, and (iii) UIS(ALL) element associated with the Dal82 and Dal81 proteins required for inducer-dependent transcription. Most of the work leading to the above conclusions has employed inducer-independent allantoin pathway genes (e.g. DAL5 and DAL3). The purpose of this work is to extend our understanding of these elements and their roles to inducible allantoin pathway genes using the DAL7 (encoding malate synthase) as a model. We show that eight distinct cis-acting sites participate in the process as follows: a newly identified GC-rich element, two UAS(NTR), two UIS(ALL), and three URS(GATA) elements. The two GATA-containing UAS(NTR) elements are coincident with two of the three GATA sequences that make up the URS(GATA) elements. The remaining URS(GATA) GATA sequence, however, is not a UAS(NTR) element but appears to function only in repression. The data provide insights into how these cis- and trans-acting factors function together to accomplish the regulated expression of the DAL7 gene that is observed in vivo. (+info)Clostridium innocuum: a glucoseureide-splitting inhabitant of the human intestinal tract. (5/150)
Glycosylureides were recently described as non-invasive markers of intestinal transit time. The underlying principle is an enzymatic splitting of (13)C-labelled ureides by intestinal bacteria. The (13)CO(2) released from the urea moiety of the glycosylureides can be measured in breath samples when the ingested tracer substrate reaches the caecum that is colonised with microbes. To date, the microbes that degrade glycosylureides are unknown. In order to identify the glucoseureide (GU)-splitting bacteria, 174 different strains of intestinal microbes obtained from five healthy adults were checked for their ability to degrade GU. The results of the microbial cultures and thin layer chromatography revealed that GU was exclusively degraded by Clostridium innocuum, belonging to the normal human intestinal microflora. C. innocuum probably synthesises a yet unknown enzyme that splits the glucose-urea bond. We suggest that the term glucoseureidehydrolase is the appropriate designation for this enzyme. (+info)Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli. (6/150)
Growth experiments with Escherichia coli have shown that this organism is able to use allantoin as a sole nitrogen source but not as a sole carbon source. Nitrogen assimilation from this compound was possible only under anaerobic conditions, in which all the enzyme activities involved in allantoin metabolism were detected. Of the nine genes encoding proteins required for allantoin degradation, only the one encoding glyoxylate carboligase (gcl), the first enzyme of the pathway leading to glycerate, had been identified and mapped at centisome 12 on the chromosome map. Phenotypic complementation of mutations in the other two genes of the glycerate pathway, encoding tartronic semialdehyde reductase (glxR) and glycerate kinase (glxK), allowed us to clone and map them closely linked to gcl. Complete sequencing of a 15.8-kb fragment encompassing these genes defined a regulon with 12 open reading frames (ORFs). Due to the high similarity of the products of two of these ORFs with yeast allantoinase and yeast allantoate amidohydrolase, a systematic analysis of the gene cluster was undertaken to identify genes involved in allantoin utilization. A BLASTP search predicted four of the genes that we sequenced to encode allantoinase (allB), allantoate amidohydrolase (allC), ureidoglycolate hydrolase (allA), and ureidoglycolate dehydrogenase (allD). The products of these genes were overexpressed and shown to have the predicted corresponding enzyme activities. Transcriptional fusions to lacZ permitted the identification of three functional promoters corresponding to three transcriptional units for the structural genes and another promoter for the regulatory gene allR. Deletion of this regulatory gene led to constitutive expression of the regulon, indicating a negatively acting function. (+info)Systematic review of comparative efficacy and tolerability of calcipotriol in treating chronic plaque psoriasis. (7/150)
OBJECTIVES: To evaluate the comparative efficacy and tolerability of topical calcipotriol in the treatment of mild to moderate chronic plaque psoriasis. DESIGN: Quantitative systematic review of randomised controlled trials. SUBJECTS: 6038 patients with plaque psoriasis reported in 37 trials. MAIN OUTCOME MEASURES: Mean difference in percentage change in scores on psoriasis area and severity index, and response rate ratios for both patients' and investigators' overall assessments of marked improvement or better. Adverse effects were estimated with the rate ratio, rate difference, and number needed to treat. RESULTS: Calcipotriol was at least as effective as potent topical corticosteroids, calcitriol, short contact dithranol, tacalcitol, coal tar, and combined coal tar 5%, allantoin 2%, and hydrocortisone 0.5%. Calcipotriol caused significantly more skin irritation than potent topical corticosteroids (number needed to treat to harm for irritation 10, 95% confidence interval 6 to 34). Calcipotriol monotherapy also caused more irritation than calcipotriol combined with a potent topical corticosteroid (6, 4 to 8). However, the number needed to treat for dithranol to produce lesional or perilesional irritation was 4 (3 to 5). On average, treating 23 patients with short contact dithranol led to one more patient dropping out of treatment owing to adverse effects than if they were treated with calcipotriol. CONCLUSIONS: Calcipotriol is an effective treatment for mild to moderate chronic plaque psoriasis, more so than calcitriol, tacalcitol, coal tar, and short contact dithranol. Only potent topical corticosteroids seem to have comparable efficacy at eight weeks. Although calcipotriol caused more skin irritation than topical corticosteroids this has to be balanced against the potential long term effects of corticosteroids. Skin irritation rarely led to withdrawal of calcipotriol treatment. Longer term comparative trials of calcipotriol versus dithranol and topical corticosteroids are needed to see whether these short term benefits are mirrored by long term outcomes such as duration of remission and improvement in quality of life. (+info)Ureide degradation pathways in intact soybean leaves. (8/150)
Ureides dramatically accumulate in shoots of N(2)-fixing soybean (Glycine max L. Merr.) under water deficit and this accumulation is higher in cultivars that have N(2) fixation that is sensitive to water deficit. One possible explanation is that ureide accumulation is associated with a feedback inhibition of nitrogenase activity. A critical factor involved in ureide accumulation is likely to be the rate of ureide degradation in the leaves. There exists, however, a controversy concerning the pathway of allantoic acid degradation in soybean. Allantoate amidinohydrolase was reported to be the pathway of degradation in studies using the cultivar Maple Arrow and allantoate amidohydrolase was the pathway that existed in the cultivar Williams. This investigation was undertaken to resolve the existence of these two pathways. An in situ technique was developed to examine the response of ureide degradation in leaf tissue to various treatments. In addition, the response of ureide accumulation and N(2) fixation activity was measured for intact plants in response to treatments that differentially influenced the two degradation pathways. The results from these studies confirmed that Maple Arrow and Williams degraded allantoic acid by different pathways as originally reported. The existence of two degradation pathways within the soybean germplasm opens the possibility of modifying ureide degradation to minimize the influence of soil water deficits on N(2) fixation activity. (+info)
Urinary Allantoin Excretion as a Marker of Microbial Crude Protein Sup by Ryan Mass, D. J. Jordon et al.
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Allantoin
... are antimicrobial condensation products of allantoin with formaldehyde. "Allantoin". "CAS # 97-59-6, Allantoin, 5- ... In fish, allantoin is broken down further (into ammonia) before excretion. Allantoin has been shown to improve insulin ... Chemically synthesized bulk allantoin, which is chemically equivalent to natural allantoin, is safe, non-toxic, compatible with ... Mutants in the B. subtilis pucI gene were unable to grow on allantoin, indicating that it encodes an allantoin transporter. In ...
Allantoin racemase
... allantoin Hence, this enzyme has one substrate, (S)(+)-allantoin, and one product, (R)(-)-allantoin. This enzyme belongs to the ... In enzymology, an allantoin racemase ({EC 5.1.99.3) is an enzyme that catalyzes the chemical reaction (S)(+)-allantoin ⇌ {\ ... The systematic name of this enzyme class is allantoin racemase. This enzyme participates in purine metabolism. Van der Drift L ... Vogels GD, Van der Drift C (1975). "Allantoin racemase: a new enzyme from Pseudomonas species". Biochim. Biophys. Acta. 391 (1 ...
Urea
Examples include carbamide peroxide, allantoin, and hydantoin. Ureas are closely related to biurets and related in structure to ...
Hemolymph
These include ammonia, allantoin, uric acid, and urea. Arthropod hormones are present, most notably the juvenile hormone. ...
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Van der Drift L, Vogels GD, Van der Drift C (1975). "Allantoin racemase: a new enzyme from Pseudomonas species". Biochim. ...
Pegloticase
Similarly to rasburicase, it metabolises uric acid to allantoin. This reduces the risk of precipitates, since allantoin is five ...
Panthenol
For this purpose, it is sometimes combined with allantoin. It binds to the hair shaft readily, so, it is a common component of ...
Hydantoin
... can also be synthesized either by heating allantoin with hydroiodic acid or by "heating bromacetyl urea with ... He obtained it by hydrogenation of allantoin, hence the name. Friedrich Urech synthesized 5-methylhydantoin in 1873 from ...
Dihydroxymalonic acid
When heated with urea to 100 °C, it forms allantoin. By continued boiling of its aqueous solution it is decomposed into carbon ...
Allantoic acid
It is a crystalline acid obtained by hydrolysis of allantoin. In nature, allantoic acid is produced from allantoin by the ...
Plantago major
Plantain contains phytochemicals including allantoin, aucubin, ursolic acid, flavonoids, and asperuloside. Plantain extract has ...
Allantoinase
In enzymology, an allantoinase (EC 3.5.2.5) is an enzyme that catalyzes the chemical reaction (S)-allantoin + H2O ⇌ {\ ... The systematic name of this enzyme class is (S)-allantoin amidohydrolase. This enzyme participates in purine metabolism. ... displaystyle \rightleftharpoons } allantoate Thus, the two substrates of this enzyme are (S)-allantoin and H2O, whereas its ...
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
It is the third step of the conversion of uric acid (a purine derivative) to allantoin. Step one is catalysed by urate oxidase ... Kim K, Park J, Rhee S (2007). "Structural and functional basis for (S)-allantoin formation in the ureide pathway". J Biol Chem ... It catalyses the decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) into S(+)-allantoin. ...
Glycolaldehyde
This is converted to 5-hydroxyisourate, which decarboxylates to allantoin and allantoic acid. After hydrolyzing one urea, this ...
Amos Frumkin
First identification of allantoin, C4H6N4O3 in Kahf Kharrat Najem Cave, United Arab Emirates. International Journal of ...
Urate oxidase
... allantoin + CO2 Uric acid 5-Hydroxyisourate Allantoin Urate oxidase is mainly localised in the liver, where it forms a large ... Urate oxidase is the first in a pathway of three enzymes to convert uric acid to S-(+)-allantoin. After uric acid is converted ... This means that instead of producing allantoin as the end product of purine oxidation, the pathway ends with uric acid. This ... However, humans lack the subsequent enzyme HIU hydroxylase in the pathway to degrade uric acid to allantoin, so long-term urate ...
Sunsilk
In 1960, Sunsilk Tonic shampoo was launched, containing the skin healing ingredient Allantoin. In 1961, Sunsilk Liquid shampoo ...
Lemmermannia
Prasad, P. V. D. (1983). Hypoxanthine and allantoin as nitrogen sources for the growth of some freshwater green algae. New ... Lemmermannia tetrapedia can use hypoxanthine and allantoin as the only nitrogen source for photosynthesis, which indicates that ...
Tissue engineering
"Fabrication and characterization of scaffolds containing different amounts of allantoin for skin tissue engineering". ...
Veganism
... allantoin- from the comfrey plant or cows' urine -is found in shampoos, moisturizers and toothpaste; and carmine from scale ...
Alloxan
The name is derived from allantoin, a product of uric acid excreted by the fetus into the allantois, and oxaluric acid derived ... The name "Alloxan" emerged from an amalgamation of the words "allantoin" and "Oxalsäure" (oxalic acid). The alloxan model of ...
Édouard Grimaux
His research included studies of nitrites, allantoin, aromatic glycols and on the synthesis of citric acid. Also, he conducted ...
Rasburicase
It is a recombinant version of urate oxidase, an enzyme that metabolizes uric acid to allantoin. Urate oxidase is known to be ... Rasburicase catalyzes enzymatic oxidation of poorly soluble uric acid into an inactive and more soluble metabolite allantoin ...
Antioxidant
In almost all land animals, urate oxidase further catalyzes the oxidation of uric acid to allantoin, but in humans and most ... The evolutionary reasons for this loss of urate conversion to allantoin remain the topic of active speculation. The antioxidant ...
Bacillus fastidiosus
... is only able to grow in the presence of uric acid, allantoin, or allantoic acid. This species has been ... Bacillus fastidious has the ability to use uricase to degrade uric acid to allantoin, and then use allantoinase to degrade ... allantoin to allantoate. It also has the ability to further break down allantoate to ammonia and ureidoglycolate via the enzyme ...
Symphytum
Comfrey contains mixed phytochemicals in varying amounts, including allantoin, mucilage, saponins, tannins, pyrrolizidine ...
Methionine
Allantoin Formylmethionine Methionine oxidation Paracetamol poisoning Photoreactive methionine S-Methylcysteine Dawson RM, ...
Insects in medicine
Maggots secrete several chemicals that kill microbes, including allantoin, urea, phenylacetic acid, phenylacetaldehyde, calcium ...
Mederma
Water (purified), PEG-4, Aloe barbadensis leaf juice, Allium cepa (onion) bulb extract, xanthan gum, allantoin, methylparaben, ... allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized ...
Diazolidinyl urea
... is produced by the chemical reaction of allantoin and formaldehyde in the presence of sodium hydroxide ...
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Allantoin: Uses, Interactions, Mechanism of Action | DrugBank Online
Allantoin is an ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. ... Allantoin. DrugBank Accession Number. DB11100. Background. Allantoin is a substance that is endogenous to the human body and ... In human muscle, urate is oxidized to allantoin during such exercise Label. The concentration of allantoin in muscles increases ... Toxnet Toxicology Data Network: Allantoin [Link] *TITCK Product Information: Noskar (allium cepa extract/allantoin/heparin ...
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Allantoin USP is a synthetic free-flowing powder used in cosmetic and pharmaceutical formulations for its soothing and anti- ... To incorporate 0.5% Allantoin, or more, into an emulsion product, the emulsion is made and Allantoin is added during the ... Allantoin stimulates healthy, normal tissue formation even at low concentrations.. While allantoin is present in botanical ... INCI: Allantoin. California Prop 65 Statement: The following statement is made in order to comply with the California Safe ...
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Density Functional Theory of a New Derivative of Allantoin with Antiplasmodial Properties, Antimycobacterial Activities of...
Results: a new allantoin (1) derivative named batesiin (2) was characterized from the EtOAc extract; thirteen known compounds ... Density Functional Theory of a New Derivative of Allantoin with Antiplasmodial Properties, Antimycobacterial Activities of ... especially the case of a derivative of allantoin (1); essential oil from Cordia batesii presents interesting antimycobacterial ... including allantoin (1) were either isolated or identified by means of MS, NMR, LC-MS and GC-MS. GC-MS was applied on a ...
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Allantoin helps to lock in moisture and Vitamin E is a natural antioxidant. Suede Aftershave balm absorbs quickly and a small ... Aftershave Balm Suede Organic Aloe Allantoin, Menthol. Gingers Garden Suede Natural Aftershave Balm is meant to soothe the ... Organic Aloe Vera, Coconut oil, Rice Bran Oil, Almond Oil, E-Wax, Mango Butter, Stearic Acid, Allantoin, Vitamin E, ... It is made with organic aloe vera, moisturizing coconut oil, soothing Allantoin, cooling menthol and natural mango butter. ...
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Benefits of Allantoin - Aqicare
What is Allantoin?. Allantoin is often used in skin care products like creams and lotions. It can also be found in different ... Allantoin is non-toxic, non-allergenic and odorless. Allantoin is widely used in skin care products because its non-toxic, non ... Allantoin helps soften and moisturise the skin. It has the ability to soften the keratin of the skin thus assisting the skin to ... Allantoin is a natural chemical compound that is often produced by animals and plants. This compound can be naturally derived ...
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Allantoin
Allantoin
... is a cosmetic ingredient with a moisturizing and keratolytic effect; increases the water content of the extracellular ... DESCRIPTION: Allantoin is a cosmetic ingredient with a moisturizing and keratolytic effect; increases the water content of the ... Allantoin is the nature-identical extract of the comfrey plant; produced synthetically for cosmetic use. A non-toxic ... SOLUBILITY: Water (0.5 at 25C) Above 0.5 in clear solutions and allantoin recrystalizes. ...
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Reference standards of Allantoin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below ... Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets Label. It is ... allantoin and its Impurities Allantoin is a substance that is endogenous to the human body and also found as a normal component ... Reference standards of Allantoin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below ...
Allantoin | Profiles RNS
"Allantoin" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Allantoin" by people in this website by year, and whether " ... Below are the most recent publications written about "Allantoin" by people in Profiles. ...
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Allantoin | Làm mỹ phẩm
Allantoin tương thích với hầu hết các thành phần trong công thức mỹ phẩm. Nhưng khó để hòa tan Allantoin trong nươ ... Để kết hợp 0.5% Allantoin vào các sản phẩm nhũ hóa, hãy cho nó vào hỗn hợp ở giai đoạn làm nguội dưới 50oC. ... Allantoin có tác dụng chống kích ứng, đặc tính làm dịu da và chữa lành vết thương , giúp loại bỏ tế bào da chết và thúc đẩy ... Trong mỹ phẩm Allantoin được dùng như
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Allantoin - The universal weapon for sensitive skin
Allantoin also optimizes the cell cohesion process of your skin and supports your moisture balance. As a result, your skins ... Now, there is a proven miracle cure for your sensitive and extremely dry skin, named Allantoin. It comes from comfrey, a root ... Allantoin promotes the acceleration of cell regeneration and restores your skins protective moisture barriers. It repairs ... The properties of the Allantoin in the lotion soothe and protect your skin. The body lotion nurtures the keratin layer and ...
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DERMATORY Allantoin Moisturizing Cream Pad 175ml. /shop/dermatory-allantoin-moisturizing-cream-pad-175ml-false-31900 58000.00 ... Allantoin, Arginine, Ceramide NP, Xanthan Gum, Panthenol, Sodium Stearoyl Glutamate, Fructooligosaccharides, Beta-Glucan, ... Allantoin, Caffeine, Hippophae Rhamnoides Fruit Extract, Daucus Carota Sativa (Carrot) Root Extract, Caprylyl Glycol, ...
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Allantoin (ALL) CAS 97-59-6 - Zhonglan Industry
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Ingredient11
- Allantoin is an ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. (drugbank.com)
- Allantoin has been classified by the FDA as an Over-The-Counter (OTC) Category I (safe and effective) active ingredient skin protectant. (lotioncrafter.com)
- Since it also has anti-inflammatory and anti-irritant properties, Allantoin is a great ingredient to use in skin care products specially made for sensitive skin. (aqicare.com)
- Skincare products that have Allantoin as an effective ingredient and have the fewest possible additives, will prevent redness, micro-cracks and dry skin. (mixa.com)
- ALLANTOIN is an effective bioactive ingredient used in a wide range of personal care formulations. (dsm.com)
- Whatever the concern we have, you covered it in the form of wonderful allantoin, an ingredient that often flies under the radar. (thenakedchemist.com)
- Allantoin used in cosmetics is a by-product of Diazolidinyl Urea's production, which is also considered a hydrating ingredient. (thenakedchemist.com)
- Allantoin has active keratolytic properties, which means it is the ideal ingredient for combatting dandruff, breaking down large particles in dead skin cells. (thenakedchemist.com)
- Allantoin is a cosmetic ingredient used in skin care products to reduce the appearance of fine lines and wrinkles, and to promote wound healing. (tkbtrading.com)
- This Anti-Aging Serum has Allantoin, a clinically proven and powerful ingredient often found in the best Anti-Aging Serums, that diminishes the appearance of scars and skin imperfections and maximally increases the smoothness of your skin so you can have your most beautiful and refreshed skin ever. (estalaskincare.com)
- ALLANTOIN a non-irritating ingredient that soothes and protects the skin. (skinlaundry.com)
Soothes2
- We absolutely recommend adding Allantoin into your routine, it soothes and speeds up skin cell turnover making a significant visible difference in your skin. (tahnyc.com)
- Shields your skin: Allantoin soothes skin irritation and therefore, it is ideal for sensitive skin. (djanillies.com)
Uric11
- More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid. (drugbank.com)
- Uricase is the enzyme that possesses the functionality to convert uric acid to allantoin. (drugbank.com)
- The presence of allantoin in human urine is subsequently the result of non-enzymatic processes on uric acid with reactive oxygen species 3 . (drugbank.com)
- Purpose of this systematic review is to summarize the current state of knowledge on changes in biomarkers (ie, oxytocin [OT], cortisol, hypoxanthine, xanthine , uric acid, and allantoin), associated with SSC in premature infants and parents, that may reflect physiologic responses to stress. (lww.com)
- Unlike allantoin, the more soluble end product of purine metabolism in lower animals, uric acid is a poorly soluble end product of purine metabolism in humans. (medscape.com)
- Recombinant form of urate oxidase (derived from Saccharomyces cerevisiae -synthesized Aspergillus flavus ), which oxidizes uric acid to allantoin (soluble and inactive). (medscape.com)
- Unlike uric acid, allantoin soluble and easily excreted by kidneys. (medscape.com)
- Allantoic acid production from IMP, XMP, inosine, xanthosine, hypoxanthine, xanthine, uric acid and allantoin was investigated by incubating each of these substrates with Cajanus cajan cytosol and bacteroid fractions separately in the presence and absence of NAD+ and allopurinol. (who.int)
- Allantoic acid synthesis by bacteroid fraction could only be observed with uric acid and allantoin as substrates. (who.int)
- With NAD+ or with allopurinol, allantoic acid was produced only with uric acid and allantoin as substrates. (who.int)
- Except with uric acid and allantoin, allopurinol completely inhibited NADH formation. (who.int)
Comfrey5
- While allantoin is present in botanical extracts of the comfrey plant, it is generally chemically synthesized to meet worldwide demand. (lotioncrafter.com)
- Allantoin is commonly found in plants like comfrey, chamomile, sugar beet and wheat sprouts. (aqicare.com)
- Allantoin is a chemical compound and is found in plants like chamomile, wheat sprouts, sugar beet and comfrey (an herb with purple flowers). (myhi9.com)
- Allantoin is found in our bodies naturally as well as in plants, it is extracted from comfrey root and is used to calm, repair and regenerate skin cells. (tahnyc.com)
- Extracted from the Comfrey plant, allantoin increases water content in the skin and enhances exfoliation improving skin smoothness. (shopbinhlamaesthetics.com)
Hyaluronic Acid1
- Bolstered by a moisturising blend of Hyaluronic Acid and Allantoin, we promise you calmer and healthier skin from the first use. (thepastelsshop.com)
Ingredients3
- Allantoin is compatible with most ingredients used in personal care formulations. (lotioncrafter.com)
- There are various skin care products that make use of Allantoin like AQI Sensitive Everyday Shampoo , CoQ10 Placenta Cream , AQI Lanolin Cream with Oatmeal And Manuka Honey 550g , AQI Lanolin Cream With Oatmeal 250g , AQI Emu Oil Extra Moisturising Cream 250g that utilises Allantoin and other natural active ingredients to cleanse the skin! (aqicare.com)
- Many products also have ingredients that soften the horny substance (keratin) that holds the top layer of skin cells together (including urea, alpha hydroxy acids such as lactic/citric/glycolic acid, and allantoin ). (webmd.com)
Powder3
- Allantoin is a synthetic, free-flowing hygroscopic powder widely used in cosmetic, dermatological and pharmaceutical formulations for its soothing and anti-irritating properties. (lotioncrafter.com)
- If you need to buy Allantoin powder, or to work with China Allantoin suppliers, manufacturers, factory directly, please feel free to contact [email protected] We guarantee to offer high quality with best Allantoin price. (chinatnj.com)
- TNJ Chemical is a China factory, supplier and manufacturer of Allantoin powder CAS 97-59-6 USP BP grade with plant site in Feidong Anhui Province. (chinatnj.com)
Witch hazel1
- Calamine 7%, Witch Hazel, Allantoin protects and hydrates sensitive skin. (beautiqn.com)
Hydrates1
- Hydrates your Skin: Allantoin helps your skin cells to retain water, making it softer and plumper. (djanillies.com)
Skin's3
- Allantoin promotes the acceleration of cell regeneration and restores your skin's protective moisture barriers. (mixa.com)
- Allantoin is clever in interacting with the skin's keratin to thin out an abnormally thick epidermis (outer layer of skin). (thenakedchemist.com)
- Allantoin and vitamin E maintain skin's moisture balance and the hydrolipid barrier. (shopbinhlamaesthetics.com)
Cosmetic2
- Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions 4 . (drugbank.com)
- Akema S.r.l. is a leading manufacturer of allantoin & cosmetic preservatives located in Italy. (akema.it)
Collagen3
- This facilitation of wound healing is supported by observations that wounds inflicted to rat subjects to which topical allantoin preparations were applied histologically demonstrated increased vasodilation, presence of inflammatory exudates, number of inflammatory cells, angiogenesis, fibroblast proliferation, and increased collagen deposition when compared to rat subjects with wounds that did not receive any allantoin administration 1 . (drugbank.com)
- Allantoin also helps synthesise collagen - a fibrous protein found in the dermis (lower layer of skin) that keeps skin elastic and supplies, decreasing with age leading to sagging skin - allantoin boosts this. (thenakedchemist.com)
- Minimizes the Signs of Aging: Allantoin assists in the synthesis of collagen-a fibrous protein known for binding the skin cells together. (djanillies.com)
Mask5
- Tell stressed, blotchy skin to cool off with Dr.Jart+'s Cryo Rubber Mask with Soothing Allantoin. (butiq.lt)
- Djanillie's Revitalizing Cay Mask contains the goodness of both Allantoin and coconut oil for soothing your tired skin. (djanillies.com)
- Salah satu alternatif eye mask yang meminimalisir ketidak cocokan atau iritasi itu yakni dengan memilih eye mask yang memilki kandungan Allantoin. (tribunnews.com)
- Kali ini Tribunshopping.com akan memberikan 5 rekomendasi eye mask yang mengandung Allantoin, dan bahan alami yang bisa menjadi refernesi kamu. (tribunnews.com)
- BREYLEE Pomegranate Eye Mask selain mengandung Allantoin, juga mengandung ekstrak buah delima. (tribunnews.com)
Urea2
- At more significant percentages, it is thought that allantoin may also have the same keratolytic effects as urea . (thenakedchemist.com)
- Hidantoína de urea que se encuesntra en la ORINA y en PLANTAS, y que se utiliza para producir preparados dermatológicos. (bvsalud.org)
Chamomile1
- Allantoin can also be extracted from wheat sprouts, sugar beets, and chamomile. (djanillies.com)
Glyoxyldiureide1
- Allantoin is also known as 5-ureidohydantoin or glyoxyldiureide. (thenakedchemist.com)
Coconut oil5
- It is made with organic aloe vera, moisturizing coconut oil, soothing Allantoin, cooling menthol and natural mango butter. (gingersgarden.com)
- How Nutrient-rich Allantoin and Coconut Oil Soothe Your Skin? (djanillies.com)
- Both allantoin and coconut oil have been used for centuries for smoother and healthier skin. (djanillies.com)
- When combined with coconut oil, the healing, and properties of Allantoin can do wonders to your sensitive, dull and lifeless skin. (djanillies.com)
- Coconut oil, on the other hand, makes your skin soft and smooth as soon as the dead skin cells are exfoliated by Allantoin. (djanillies.com)
Anti-irritant1
- Allantoin is well known for treating burns, wounds and scars because of its anti-inflammatory and anti-irritant properties. (aqicare.com)
Redness2
- Allantoin has anti-inflammatory property that can soothe irritated skin as well as help reduce redness. (aqicare.com)
- Allantoin Serum Water can be paired with Exfoliants, Retinol and Acids to help skin heal and calm redness pre and post treatment. (tahnyc.com)
Chemical compound1
- Allantoin is a natural chemical compound that is often produced by animals and plants. (aqicare.com)
Soothe1
- The properties of the Allantoin in the lotion soothe and protect your skin. (mixa.com)
Keratolytic effects1
- Nevertheless, ongoing studies suggest that allantoin possesses moisturizing and keratolytic effects, as well as abilities to increase the water content of the extracellular matrix and enhance the desquamation of upper layers of dead skin cells, all of which are activities that can promote cell proliferation and facilitate wound healing 1 . (drugbank.com)
Increases3
- During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated Label . (drugbank.com)
- The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise Label . (drugbank.com)
- Allantoin increases the smoothness of the skin and provides a skin protectant effect. (skinactives.com)
Cosmetics1
- 2. In cosmetics, Allantoin can be directly or indirectly used in cosmetics and other daily chemical products, such as toothpaste, shampoo, soap etc. (chinatnj.com)
Exfoliation1
- As discussed in the exfoliation section - allantoin, by its very nature, is keratolytic, gently softening the keratin and keeping the skin smooth. (thenakedchemist.com)