Salts of alginic acid that are extracted from marine kelp and used to make dental impressions and as absorbent material for surgical dressings.
Term used to designate tetrahydroxy aldehydic acids obtained by oxidation of hexose sugars, i.e. glucuronic acid, galacturonic acid, etc. Historically, the name hexuronic acid was originally given to ascorbic acid.
A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.
A group of carbon-oxygen lyases. These enzymes catalyze the breakage of a carbon-oxygen bond in polysaccharides leading to an unsaturated product and the elimination of an alcohol. EC 4.2.2.
Microbial, plant, or animal cells which are immobilized by attachment to solid structures, usually a column matrix. A common use of immobilized cells is in biotechnology for the bioconversion of a substrate to a particular product. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.
Stable strontium atoms that have the same atomic number as the element strontium, but differ in the atomic weight. Sr-84, 86, 87, and 88 are the stable strontium isotopes.
Substances used to create an impression, or negative reproduction, of the teeth and dental arches. These materials include dental plasters and cements, metallic oxide pastes, silicone base materials, or elastomeric materials.
A genus of BROWN ALGAE in the family Laminariaceae. Dried pencil-like pieces may be inserted in the cervix where they swell as they absorb moisture, serving as osmotic dilators.
Reversibly catalyze the oxidation of a hydroxyl group of carbohydrates to form a keto sugar, aldehyde or lactone. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.; EC 1.1.2.; and 1.1.99.
Hard or soft soluble containers used for the oral administration of medicine.
Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.
Acids derived from monosaccharides by the oxidation of the terminal (-CH2OH) group farthest removed from the carbonyl group to a (-COOH) group. (From Stedmans, 26th ed)
Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)
A genus of gram-negative, aerobic, rod-shaped bacteria characterized by an outer membrane that contains glycosphingolipids but lacks lipopolysaccharide. They have the ability to degrade a broad range of substituted aromatic compounds.
Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.
Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.
An enzyme that catalyzes the reversible isomerization of D-mannose-6-phosphate to form D-fructose-6-phosphate, an important step in glycolysis. EC
A hydrated form of silicon dioxide. It is commonly used in the manufacture of TOOTHPASTES and as a stationary phase for CHROMATOGRAPHY.
The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
Chemicals especially for use on instruments to destroy pathogenic organisms. (Boucher, Clinical Dental Terminology, 4th ed)
A species of gram-negative, aerobic bacteria first isolated from soil in Vineland, New Jersey. Ammonium and nitrate are used as nitrogen sources by this bacterium. It is distinguished from other members of its genus by the ability to use rhamnose as a carbon source. (From Bergey's Manual of Determinative Bacteriology, 9th ed)
A genus of BROWN ALGAE in the family Lessoniaceae, and one of the major forms of KELP. The species Macrocystis pyrifera, also known as giant kelp, is the largest of the marine algae.
A network of cross-linked hydrophilic macromolecules used in biomedical applications.
A group of enzymes that catalyze an intramolecular transfer of a phosphate group. It has been shown in some cases that the enzyme has a functional phosphate group, which can act as the donor. These were previously listed under PHOSPHOTRANSFERASES (EC 2.7.-). (From Enzyme Nomenclature, 1992) EC 5.4.2.
A calcium salt that is used for a variety of purposes including: building materials, as a desiccant, in dentistry as an impression material, cast, or die, and in medicine for immobilizing casts and as a tablet excipient. It exists in various forms and states of hydration. Plaster of Paris is a mixture of powdered and heat-treated gypsum.
The study of the structure, growth, function, genetics, and reproduction of bacteria, and BACTERIAL INFECTIONS.
A publication issued at stated, more or less regular, intervals.
The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
The collection, writing, and editing of current interest material on topics related to biomedicine for presentation through the mass media, including newspapers, magazines, radio, or television, usually for a public audience such as health care consumers.
Salts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Multicellular marine macroalgae including some members of red (RHODOPHYTA), green (CHLOROPHYTA), and brown (PHAEOPHYTA) algae. They are widely distributed in the ocean, occurring from the tide level to considerable depths, free-floating (planktonic) or anchored to the substratum (benthic). They lack a specialized vascular system but take up fluids, nutrients, and gases directly from the water. They contain CHLOROPHYLL and are photosynthetic, but some also contain other light-absorbing pigments. Many are of economic importance as FOOD, fertilizer, AGAR, potash, or source of IODINE.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Compounds used in food or in food preparation to replace dietary fats. They may be carbohydrate-, protein-, or fat-based. Fat substitutes are usually lower in calories but provide the same texture as fats.
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Herbaceous biennial plants and their edible bulbs, belonging to the Liliaceae.
Dressings comprised of a self-adhesive matrix to which hydrophilic absorbent particles are embedded. The particles consist of CELLULOSE derivatives; calcium ALGINATES; PECTINS; or GELS. The utility is based on providing a moist environment for WOUND HEALING.
Material used for wrapping or binding any part of the body.
Human or animal tissue used as temporary wound coverings.
Maintenance of the hygienic state of the skin under optimal conditions of cleanliness and comfort. Effective in skin care are proper washing, bathing, cleansing, and the use of soaps, detergents, oils, etc. In various disease states, therapeutic and protective solutions and ointments are useful. The care of the skin is particularly important in various occupations, in exposure to sunlight, in neonates, and in PRESSURE ULCER.
A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.
Stable iron atoms that have the same atomic number as the element iron, but differ in atomic weight. Fe-54, 57, and 58 are stable iron isotopes.
Iron or iron compounds used in foods or as food. Dietary iron is important in oxygen transport and the synthesis of the iron-porphyrin proteins hemoglobin, myoglobin, cytochromes, and cytochrome oxidase. Insufficient amounts of dietary iron can lead to iron-deficiency anemia.
Recording of visual and sometimes sound signals on magnetic tape.
The industry concerned with processing, preparing, preserving, distributing, and serving of foods and beverages.
The storing or preserving of video signals for television to be played back later via a transmitter or receiver. Recordings may be made on magnetic tape or discs (VIDEODISC RECORDING).
Polymers where the main polymer chain comprises recurring amide groups. These compounds are generally formed from combinations of diamines, diacids, and amino acids and yield fibers, sheeting, or extruded forms used in textiles, gels, filters, sutures, contact lenses, and other biomaterials.
A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
Proteins that cotransport sodium ions and bicarbonate ions across cellular membranes.

Purification and properties of an alginate lyase from a marine bacterium. (1/937)

An unidentified pseudomonad isolated by enrichment procedures from decomposing seaweed was grown in defined medium containing sodium alginate as the sole carbon source. The alginate lyase recovered from disrupted bacterial cells was purified by a procedure of (NH4)2SO4 precipitation, gel filtration and ion-exchange chromatography. From sodium dodecyl sulphate/polyacrylamide-gel-electrophoresis experiments a mol.wt. of about 50 000 was determined. The enzyme was active against both algal and bacterial alginate preparations. Kinetic studies together with analysis of the unsaturated oligouronide products of alginate lyase action indicated the enzyme was specific for guluronic acid-containing regions of the macromolecular substrate. The specificity of the enzyme can be used to give information about the primary composition of alginate samples.  (+info)

Matrix degradation by chondrocytes cultured in alginate: IL-1 beta induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation. (2/937)

OBJECTIVE: To determine the role of interleukin-1 beta (IL-1 beta) in the degradation of proteoglycans and collagen by articular chondrocytes. DESIGN: Chondrocytes were cultured in alginate beads for 2 weeks to produce extracellular matrix, followed by the addition of IL-1 beta for 1 or 2 days. Breakdown of extracellular matrix (with and without activation of pro-matrix metalloproteinases (MMPs) by APMA) was monitored by release of glycosaminoglycans (GAG, proteoglycans) and hydroxyproline (collagen) from the beads into the medium, and by the amount of damaged collagen in the bead. Levels of (pro)MMPs in the beads were assayed by zymography and their activity was quantified fluorometrically. RESULTS: IL-1 beta induced a profound GAG release (approximately 80% after 2 days at 20 ng/ml IL-1 beta) that was both time and IL-1 beta concentration dependent. Under these conditions no increase in collagen release or damaged collagen in the bead was detected. Zymography demonstrated that the synthesis of a variety of proMMPs was induced by IL-1 beta, without a detectable increase of MMP-activity as measured in the activity assay. After activation of the proMMPs by APMA, a time and IL-1 beta concentration-dependent increase in MMP-activity was found, which resulted in almost complete deterioration of collagen already after 18 h of incubation. In the presence of APMA, GAG release from IL-1 beta treated beads was significantly increased from 24 to 31%. CONCLUSIONS: Our data suggest that proteoglycan and collagen degradation are regulated through different mechanisms: IL-1 beta induces the synthesis of active enzymes that degrade proteoglycans, such as 'aggrecanase', and inactive proMMPs. Thus, IL-1 beta alone is not sufficient to result in collagen-degrading MMPs. Once activated, MMPs may account for up to a quarter of the aggrecan degradation in this model.  (+info)

Factors affecting dimensional instability of alginate impressions during immersion in the fixing and disinfectant solutions. (3/937)

To clarify the factors determining the dimensional stability of alginate impressions during immersion in disinfectant and fixing solution, the weight change of impressions in solutions of glutaraldehyde (GA), NaClO, Na2SO4, K2SO4, CaCl2, and ZnSO4 was measured. In the nonelectrolytic solution, GA, the weight decreased in proportion to concentration, possibly due to the gradient of osmotic pressure between the impression and solution. In monovalent metallic salt solutions the weight change decreased with increased concentration. Especially at lower concentrations the rate of weight loss was high. A chemical action of the solution might also be involved, in addition to the osmotic pressure difference. The weight loss in divalent metallic salt solutions was greater than in monovalent solutions, implicating crosslinking reactions between the impression and solution.  (+info)

Study of the response of a biofilm bacterial community to UV radiation. (4/937)

We have developed a bioluminescent whole-cell biosensor that can be incorporated into biofilm ecosystems. RM4440 is a Pseudomonas aeruginosa FRD1 derivative that carries a plasmid-based recA-luxCDABE fusion. We immobilized RM4440 in an alginate matrix to simulate a biofilm, and we studied its response to UV radiation damage. The biofilm showed a protective property by physical shielding against UV C, UV B, and UV A. Absorption of UV light by the alginate matrix translated into a higher survival rate than observed with planktonic cells at similar input fluences. UV A was shown to be effectively blocked by the biofilm matrix and to have no detectable effects on cells contained in the biofilm. However, in the presence of photosensitizers (i.e., psoralen), UV A was effective in inducing light production and cell death. RM4440 has proved to be a useful tool to study microbial communities in a noninvasive manner.  (+info)

The A modules of the Azotobacter vinelandii mannuronan-C-5-epimerase AlgE1 are sufficient for both epimerization and binding of Ca2+. (5/937)

The industrially important polysaccharide alginate is composed of the two sugar monomers beta-D-mannuronic acid (M) and its epimer alpha-L-guluronic acid (G). In the bacterium Azotobacter vinelandii, the G residues originate from a polymer-level reaction catalyzed by one periplasmic and at least five secreted mannuronan C-5-epimerases. The secreted enzymes are composed of repeats of two protein modules designated A (385 amino acids) and R (153 amino acids). The modular structure of one of the epimerases, AlgE1, is A1R1R2R3A2R4. This enzyme has two catalytic sites for epimerization, each site introducing a different G distribution pattern, and in this article we report the DNA-level construction of a variety of truncated forms of the enzyme. Analyses of the properties of the corresponding proteins showed that an A module alone is sufficient for epimerization and that A1 catalyzed the formation of contiguous stretches of G residues in the polymer, while A2 introduces single G residues. These differences are predicted to strongly affect the physical and immunological properties of the reaction product. The epimerization reaction is Ca2+ dependent, and direct binding studies showed that both the A and R modules bind this cation. The R modules appeared to reduce the Ca2+ concentration needed for full activity and also stimulated the reaction rate when positioned both N and C terminally.  (+info)

Regulation of alginate biosynthesis in Pseudomonas syringae pv. syringae. (6/937)

Both Pseudomonas aeruginosa and the phytopathogen P. syringae produce the exopolysaccharide alginate. However, the environmental signals that trigger alginate gene expression in P. syringae are different from those in P. aeruginosa with copper being a major signal in P. syringae. In P. aeruginosa, the alternate sigma factor encoded by algT (sigma22) and the response regulator AlgR1 are required for transcription of algD, a gene which encodes a key enzyme in the alginate biosynthetic pathway. In the present study, we cloned and characterized the gene encoding AlgR1 from P. syringae. The deduced amino acid sequence of AlgR1 from P. syringae showed 86% identity to its P. aeruginosa counterpart. Sequence analysis of the region flanking algR1 in P. syringae revealed the presence of argH, algZ, and hemC in an arrangement virtually identical to that reported in P. aeruginosa. An algR1 mutant, P. syringae FF5.32, was defective in alginate production but could be complemented when algR1 was expressed in trans. The algD promoter region in P. syringae (PsalgD) was also characterized and shown to diverge significantly from the algD promoter in P. aeruginosa. Unlike P. aeruginosa, algR1 was not required for the transcription of algD in P. syringae, and PsalgD lacked the consensus sequence recognized by AlgR1. However, both the algD and algR1 upstream regions in P. syringae contained the consensus sequence recognized by sigma22, suggesting that algT is required for transcription of both genes.  (+info)

Biodegradable alginate microspheres as a delivery system for naked DNA. (7/937)

Sodium alginate is a naturally occurring polysaccharide that can easily be polymerized into a solid matrix to form microspheres. These biodegradable microspheres were used to encapsulate plasmid DNA containing the bacterial beta-galactosidase (LacZ) gene under the control of either the cytomegalovirus (CMV) immediate-early promoter or the Rous sarcoma virus (RSV) early promoter. Mice inoculated orally with microspheres containing plasmid DNA expressed LacZ in the intestine, spleen and liver. Inoculation of mice with microspheres containing both the plasmid DNA and bovine adenovirus type 3 (BAd3) resulted in a significant increase in LacZ expression compared to those inoculated with microspheres containing only the plasmid DNA. Our results suggest that adenoviruses are capable of augumenting transgene expression by plasmid DNA both in vitro and in vivo.  (+info)

R-factor inheritance and plasmid content in mucoid Pseudomonas aeruginosa. (8/937)

Eighteen strains of alginate-producing mucoid Pseudomonas aeruginosa were evaluated with respect to plasmid content and the ability to maintain well-characterized R plasmids. The spontaneous loss of alginate production in these strains varied from 0.01 to 0.7% and was not significantly increased by plasmid curing regimens. Examination of cleared lysates of these strains and their isogenic nonmucoid derivatives by agarose gel electrophoresis failed to reveal plasmid DNA. R-plasmid (P-incompatibility-group) transfer to mucoid P. aeruginosa was unaffected by the presence of the alginate capsule. Maintenance and expression of such plasmids in the mucoid strains were confirmed by agarose gel electrophoresis and by verification of plasmid-linked drug resistance and pilus-specific bacteriophage sensitivity. These studies demonstrate that alginate production does not appear to be plasmid linked and that mucoid P. aeruginosa are capable of receiving and donating certain drug resistance plasmids. Since some of the plasmids used here have been shown to mobilize chromosomal DNA, strains constructed in this study should afford the means for exploring the genetic basis of the mucoid phenotype.  (+info)

Calcium alginate is a water-insoluble, gelatinous, cream-coloured substance that can be created through the addition of aqueous calcium chloride to aqueous sodium alginate. Calcium alginate is also used for entrapment of enzymes and forming artificial seeds in plant tissue culture. Alginate is usually the salts of alginic acid, but it can also refer to derivatives of alginic acid and alginic acid itself; in some publications the term algin is used instead of alginate. Alginate is present in the cell walls of brown algae, as the calcium, magnesium and sodium salts of alginic acid. To extract the alginate, the seaweed is broken into pieces and stirred with a hot solution of an alkali, usually sodium carbonate. Over a period of about two hours, the alginate dissolves as sodium alginate to give a very thick slurry. This slurry also contains the part of the seaweed that does not dissolve, mainly cellulose. This insoluble residue must be removed from the solution. The solution is too thick ...
Like many natural polysaccharides, dried alginates are not stable to heat, oxygen, metallic ions, etc. Stored in such circumstances, alginates will be degraded naturally. The high-viscosity alginate is more rapidly degraded than the medium-or low- viscosity ones. The order of stability in storage is: sodium alginate , ammonium alginate , alginic acid.. Different kind of alginate salt gives different stability, so does the different grade product. The industrial grade alginate solution is more easily degraded by microbe in the air, because such products contain much algal particles and nitrogenous matter which offer plenty of nutrition for microbe. The pure sodium alginate solution can be kept at room temperature for several months without obvious change in viscosity. When temperature increases, all alginate solutions will depolymerize. Alginate solutions are stable in the pH range 5.5 - 10 at room temperature for a long time, but will form the gel below pH 5.5. Propylene glycol alginate solution ...
Grape juice can be easily contaminated with ochratoxin A (OTA), one of the known mycotoxins with the greatest public health significance. Among the different approaches to decontaminate juice from this mycotoxin, microbiological methods proved efficient, inexpensive and safe, particularly the use of yeast or yeast products. To ascertain whether immobilisation of the yeast biomass would lead to successful decontamination, alginate beads encapsulating Candida intermedia yeast cells were used in our experiments to evaluate their OTA-biosorption efficacy. Magnetic calcium alginate beads were also prepared by adding magnetite in the formulation to allow fast removal from the aqueous solution with a magnet. Calcium alginate beads were added to commercial grape juice spiked with 20μg/kg OTA and after 48h of incubation a significant reduction (,80%), of the total OTA content was achieved, while in the subsequent phases (72-120h) OTA was slowly released into the grape juice by alginate beads. ...
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TY - JOUR. T1 - The effect of sodium alginate on physical and dissolution properties of Surelease®-matrix pellets prepared by a novel pelletizer. AU - Kim, Min Soo. AU - Kim, Jeong Soo. AU - Hwang, Sung Joo. PY - 2007/11/1. Y1 - 2007/11/1. N2 - The aim of this study was to investigate the effect of sodium alginate on the physical and dissolution properties of Surelease®-matrix pellets prepared by a novel pelletizer-equipped piston extruder and double-arm counter-rotating rollers. The mean values of the shape factor (eR) and the aspect ratio of Surelease®-matrix pellets were 0.615-0.625 and 1.06-1.070, respectively, indicating good sphericity of the pellets. The drug release rate increased as the amount of sodium alginate increased due to hydration, swelling, and erosion within the Surelease®-matrix pellets. In addition, the porosity of pellets also increased with increasing sodium alginate content. The results of this study show that sodium alginate has a greater effect on the drug release ...
Press Release issued Apr 30, 2019: There are several types of alginates available in the global market including sodium, calcium, and potassium out of which sodium alginates hold the highest share of the market. Sodium alginate is a type of natural polysaccharide which is extracted from the brown seaweed that grows in cold water regions. Sodium alginate market is expanding mainly on account of the increasing size of food industry. Sodium alginate is soluble in cold and hot water, and possesses thickening and binding properties. Sodium alginate forms a gel without being heated in the presence of calcium. Sodium alginate is generally used along with calcium salts in several cuisines to produce small and large spheres filled with liquid that burst in the mouth. Sodium Alginate is also used in the food industry as an emulsifier to increase viscosity. It is also used in indigestion tablets as it does not have any discernible flavor.
The report on the Global Sodium Alginate market offers complete data on the Sodium Alginate market. Components, for example, main players, analysis, size, situation of the business, SWOT analysis, and best patterns in the market are included in the report. In addition to this, the report sports numbers, tables, and charts that offer a clear viewpoint of the Sodium Alginate market. The top contenders SNP, KIMICA, SNAP Natural & Alginate Products, IRO Alginate Industry, NovaMatrix, Bright Moon Seaweed, Lianyungang Tiantian Seaweed Industrial, Unikem of the global Sodium Alginate market are further covered in the report .. Access to the sample pages of the report at: The report also segments the global Sodium Alginate market based on product mode and segmentation Industrial Grade, Food Grade, Pharma Grade. The study includes a profound summary of the key sectors and the segments Papermaking, Paper Coatings, Textiles, Food & ...
There have been few studies of the effect of alginate dressings on the processes of wound healing.. The healing of cutaneous ulcers requires the development of a vascularized granular tissue bed, filling of large tissue defects by dermal regeneration, and the restoration of a continuous epidermal keratinocyte layer. These processes were modeled in vitro in one study, utilizing human dermal fibroblast, microvascular endothelial cell (HMEC), and keratinocyte cultures to examine the effect of calcium alginate on the proliferation and motility of these cultures, and the formation of capillarylike structures by HMEC.. In the study, the calcium alginate increased the proliferation of fibroblasts but decreased the proliferation of HMEC and keratinocytes. In contrast, the calcium alginate decreased fibroblast motility but had no effect on keratinocyte motility. There was no significant effect of calcium alginate on the formation of capillarylike structures by HMEC. The effects of calcium alginate on ...
Sodium Alginate Market by Product (Food Grade Sodium Alginate, Pharmaceutical Grade Sodium Alginate, Technical Grade Sodium Alginate, Feed Grade Sodium Alginate), by Application (Food Additives, Pharmaceutical & Healthcare, Paper & Pulp, Personal Care & Cosmetics, Textile, Animal Feed, Industrial) and by Region, Trend, Forecast, Competitive Analysis, and Growth Opportunity 2019-2024 - Radiant Insights
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Figure 1, a) 3D pore 100 µm droplet chip junction, b) 80 µm, c) 100 µm alginate beads.. The Dolomite Team is using microfluidics to produce small (80-120 µm) alginate beads suitable for cell encapsulation. A 2 % alginate solution was dissolved in water overnight with subsequent addition of Ca-EDTA. For the oil phase, 1 % Fluosurf in HFE 7500 was used with 0.05 % acetic acid to release the chelated calcium in the Ca-EDTA complex and allow alginate crosslinking from within. Both solutions were introduced into a 100 µm 3D pore fluorophilic single junction chip (figure 1a) to form spherical monodispersed beads. Depending on flow rates (Qd 16 µlmin-1 Qc 10 µlmin-1 and Qd 10 µlmin-1 Qc 18 µlmin-1) 80 µm (figure 1b) and 100 µm (figure 1c) alginate beads were produced respectively.. DOWNLOAD APPLICATION NOTE HERE. If you are interested in producing alginate beads for your applications, please contact us at [email protected], and keep an eye out for our alginate bead application ...
Alginate is a biodegradable, immunocompatible biopolymer that is capable of immobilizing viable cells and bioactive factors. Few investigations have analyzed the efficacy of alginate gels as substrata for cell attachment and proliferation. Here we have compared the adhesion and subsequent growth of human and rat bone marrow stromal fibroblastic cells on unmodified alginate hydrogel surfaces. It was found that, in contrast to rat cells, human cells did not readily attach or proliferate on unmodified alginates. In attempts to enhance these features, or collagen type I was incorporated into the gels, with no significant improvements in prolonged human cell adherence. However, alginate gels containing both collagen type I and beta-tricalcium phosphate were found to enhance human cell adherence and proliferation. Furthermore, interactions between the collagen and beta-tricalcium phosphate prevented loss of the protein from the hydrogels. These results indicate that alginate gels containing collagen have
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This study explores the utility of calcium-alginate hydrogels as a three-dimensional culture platform for hematopoietic cell culture. We investigate the effects of calcium concentration and alginate viscosity on the mechanical and physical properties of the gel, and their subsequent effects on cellular growth. Further, we have also explored the establishment of a co-culture system in the presence of stromal cells (HS-5) and using K562 cells as our hematopoietic model. Physical characterization of calcium alginate is conducted with mechanical testing and Scanning Electron Microscope (SEM) scans to determine the relationship between the mechanical strength and the structure of calcium alginate with the variation of calcium concentration and alginate viscosity. The study on mechanical properties via compressive stress test reveals that increasing calcium concentration and alginate viscosity resulted in the formation of stiffer gels as showed by the higher elastic moduli. In addition, SEM scans ...
The influence of the mixture of water and alcohols on the solubility and properties of alginate and its calcium-induced gels is of interest for the food, wound care and pharmaceutical industries. The solvent quality of water with increasing amounts of ethanol (0-20%) on alginate was studied using intrinsic viscosity. The effect of ethanol addition on the rheological and mechanical properties of calcium alginate gels was determined. Small-angle X-ray scattering and transmission electron microscopy were used to study the network structure. It is shown that the addition of ethanol up to 15% (wt) increases the extension of the alginate chain, which correlates with increased moduli and stress being required to fracture the gels. The extension of the polymer chain is reduced at 20% (wt) ethanol, which is followed by reduced moduli and stress at breakage of the gels. The network structure of gels at high ethanol concentrations (24%) is characterized by thick and poorly connected network strands.. ...
Alginate hydrogels are commonly used in biomedical applications such as scaffolds for tissue engineering, drug delivery, and as a medium for cell immobilization. Multivalent cations are often employed to create physical crosslinks between carboxyl and hydroxyl moieties on neighbouring polysaccharide chains, creating hydrogels with a range of mechanical properties. This work describes the manufacture and characterisation of sodium alginate hydrogels using the divalent cations Mg2+, Ca2+ and Sr2+ to promote gelation via non-covalent crosslinks. The gelation time and Youngs modulus are characterised as a function of cation and alginate concentrations. The implications of this work towards the use of environmental elasticity to control stem cell differentiation are discussed.. ...
Sodium and potassium alginate are intended to be used as technological additives (functional groups: emulsifiers, stabilisers, thickeners, gelling agents and binders). Sodium alginate is intended to be used in feedingstuffs for pets, other non food-producing animals and fish, with no maximum recommended use level. Potassium alginate is intended to be used in feedingstuffs for cats and dogs at levels up to 40,000 mg/kg feed (on dry matter). Since the functional properties of the additives are determined by the alginate content, sodium and potassium alginate were considered equivalent. The maximum dose considered safe for cats, dogs, other non food-producing animals, salmonids and other fish is 40,000 mg alginates (sodium and potassium salts)/kg complete feed. The use of alginates in feedingstuffs for fish is of no concern for the consumer. Alginates are reported not to be irritant to the skin but mildly irritant to the eyes. They are considered as potential sensitisers to the skin and the ...
TY - JOUR. T1 - Oxidised alginate hydrogels as niche environments for corneal epithelial cells. AU - Wright, Bernice. AU - De Bank, Paul A.. AU - Luetchford, Kimberley. AU - Acosta, Fernando R.. AU - Connon, Che J.. PY - 2014/10. Y1 - 2014/10. N2 - Chemical and biochemical modification of hydrogels is one strategy to create physiological constructs that maintain cell function. The aim of this study was to apply oxidised alginate hydrogels as a basis for development of a biomimetic niche for limbal epithelial stem cells that may be applied to treating corneal dysfunction. The stem phenotype of bovine limbal epithelial cells (LEC) and the viability of corneal epithelial cells (CEC) were examined in oxidised alginate gels containing collagen IV over a 3-day culture period. Oxidation increased cell viability (P ≤ 0.05) and this improved further with addition of collagen IV (P ≤ 0.01). Oxidised gels presented larger internal pores (diameter: 0.2 - 0.8 µm) than unmodified gels (pore diameter: ...
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Humidity: sunny, mild humidity Using our observations from Experiment #2, we decided to start with a 1:24 ratio of sodium alginate to Future floor polish because this ratio produced a solution with the right combination of fluidity and thickness for a ground.. To begin the experiment we mixed ½ tbs of Sodium alginate and ¾ cup of Zea Mays Stop out to achieve a 1:24 ratio.. This mixture was not fluid like we expected. It immediately started clumping up and became thicker than we anticipated. We hypothesized the different results were due to addition of Gac 100, which is part of the stop out mixture. The Gac 100 was not included in our first test with a 1:24 ratio. In the first test, just future floor polish was mixed with sodium alginate. We let the sodium alginate and stop out mixture sit for three hours to see if over time the clumps would dissolve. After three hours of sitting with periodic stirring, the mixture was still very lumpy and thick. This ratio,1 part sodium alginate to 24 parts ...
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Oxygen-dependent alginate synthesis and enzymes in Pseudomonas aeruginosa.: Alginate production by the highly alginate-producing Pseudomonas aeruginosa 8821M wa
Objective(s): In this study, effects of encapsulated umbilical cord stem cells (UCSCs)-derived hepatocyte-like cells (HLCs) in high mannuronic alginate scaffolds was investigated on CCl4-induced acute liver failure (ALF) in rats. Material and Methods: UCSCs were encapsulated in high mannuronic alginate scaffolds. Then the UCSCs differentiated into HLCs for treatment of CCl4-induced ALF in rats. Thirty rats randomly divided into 5 groups: Intoxicated group received only CCl4 to induce ALF. In other groups including cell-free, UCSCs and HLCs, alginate scaffolds were transplanted into the liver 4 days after CCl4 injection. Biochemical markers including albumin (ALB), blood urea nitrogen (BUN), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) were evaluated. Histological changes and gene expression of ALB, alpha-fetoprotein (AFP), and cytokeratin 18 (CK-18) were also assessed.Results: Expression of CK-18 significantly increased in HLCs compared to the UCSCs
lginate is a polysaccharide found within brown seaweeds and has been targeted as a carbon source for biofuel production. Alginate consists of α-L-guluronate (G) and β-D-mannuronate (M) linked in various patterns, which results in either a homo- or heteropolymeric structure. Alginate lyases are enzymes that degrade the linkage between G and M blocks and can have specificity to either polyG, polyM, or polyMG block degradation. The marine bacterium Vibrio splendidus 12B01 contains four putative alginate lyases which were investigated in this study. We identified, purified, and characterized the four PL7 alginates lyases. We found that these lyases have optimal activity between pH 7.5-8.5 and 20-25°C, consistent with use in a marine environment. Additionally, Ca 2+ is necessary for optimal enzyme activity. The binding constant (K m ) of the lyases toward alginate was found to be between 22 and 123 mM alginate and the maximum reaction rate (V max ) was found to be between 0.13 and 0.83 μM s -1 . ...
Alginates have many beneficial uses across a wide variety of industries. Alginates are salts of alginic acid taking the form of sodium, calcium and/or ammonium alginate precipitated from brown seaweed (algae).
TY - JOUR. T1 - Controlling alginate gel degradation utilizing partial oxidation and bimodal molecular weight distribution. AU - Boontheekul, Tanyarut. AU - Kong, Hyun Joon. AU - Mooney, David J.. N1 - Funding Information: The author would like to thank NIDCR/NIH for financial support (RO1 DE13349), as well as Royal King Anandamahidol foundation (Thailand) for a graduate fellowship to T.B.. PY - 2005/5. Y1 - 2005/5. N2 - Degradability is often a critical property of materials utilized in tissue engineering. Although alginate, a naturally derived polysaccharide, is an attractive material due to its biocompatibility and ability to form hydrogels, its slow and uncontrollable degradation can be an undesirable feature. In this study, we characterized gels formed using a combination of partial oxidation of polymer chains and a bimodal molecular weight distribution of polymer. Specifically, alginates were partially oxidized to a theoretical extent of 1% with sodium periodate, which created acetal ...
All chronic wounds are colonised by bacteria; for some, colonisation progresses to become infection. Alginate wound dressings are used for highly exuding chronic wounds as they are very absorbent, taking up large quantities of exudate while maintaining a moist wound bed to support healing. Some alginate dressings are doped with antimicrobials, most commonly silver, but evidence regarding the efficacy of these is largely inconclusive. This manuscript describes the development and in vitro assessment of alginate materials doped with chlorhexidine hexametaphosphate (CHX-HMP), a sparingly soluble salt which when exposed to aqueous environments provides sustained release of the common antiseptic chlorhexidine. Comparator materials were a commercial silver alginate dressing material and an alginate doped with chlorhexidine digluconate (CHXdg). CHX-HMP alginates provided a dose-dependent CHX release which was sustained for over 14 days, whereas CHXdg alginates released limited CHX and this ceased ...
Research work that began in 2013 has been able to establish, optimise and standardise the cultivation of the soil bacterium and the biotechnological process for producing and isolating bacterial alginates. By working specifically on optimising the bacteriums alginate biosynthesis, the researchers succeeded in improving the composition, and therefore the properties and yield of the alginate. This meant that they could make customised alginates that are particularly suitable for producing fibres for use in medical products. In a pilot production facility, the research partners were able to spin fibres from alginate and alginate-viscose, and turn them into innovative nonwoven materials and wound dressings within the established process. When the new wound dressings were tested in use, the alginate product that had been made using biotechnology was impressive for its liquid absorption capacity, which was significantly better than that of commercially available marine alginate-based wound dressings. ...
The high cost of soluble enzymes can limit their use for commercial and industrial purposes. Immobilization can enhance enzyme reusability, thereby reducing product isolation costs and overcoming this economic barrier. In the current study, two novel, purified lipases from Pseudomonas sp. (Pseudomonas reinekei and Pseudomonas brenneri) were entrapped in a calcium alginate matrix, with the aim of simultaneously enhancing enzyme reusability and stability. Following entrapment, the retained activity of the enzyme-alginate composite was verified by an enzymatic hydrolysis reaction of a p-nitrophenol palmitate substrate. The effect of the enzyme-alginate entrapment against various physiochemical parameters such as pH, temperature, metal ions, and solvents were subsequently examined. The entrapment was found to have minimal beneficial stability gains. However, enhanced enzyme reusability (up to 3 cycles) and stability (up to 18 days at 4°C) of the calcium alginate entrapped lipase, as indicated by
The relationship of high and low molecular weight mannuronic acid (M)- and guluronic acid (G)-rich alginate nanoparticles as oral insulin carrier was elucidated. Nanoparticles were prepared through ionotropic gelation using Ca2 +, and then in vitro physicochemical attributes and in vivo antidiabetic characteristics were examined. The alginate nanoparticles had insulin release retarded when the matrices had high alginate-to-insulin ratio or strong alginate-insulin interaction via O-H moiety. High molecular weight M-rich alginate nanoparticles were characterized by assemblies of long polymer chains that enabled insulin encapsulation with weaker polymer-drug interaction than nanoparticles prepared from other alginate grades. They were able to encapsulate and yet release and have insulin absorbed into systemic circulation, thereby lowering rat blood glucose. High molecular weight G- and low molecular weight M-rich alginate nanoparticles showed remarkable polymer-insulin interaction. This retarded ...
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The analysts forecast the global sodium alginate market to exhibit a CAGR of 5.43% during the period 2019-2024. The report covers the present scenario and the growth prospects of the global sodium alginate for 2019-2024. To calculate the market size, the report considers the sodium alginate sales volume and revenue.. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: regional markets, product, and application.. Download Free Sample Report @ Geographically, the global sodium alginate market is segmented into North America, Asia Pacific, Europe, Middle East & Africa and South America. This report forecasts revenue growth at a global, regional & country level, and provides an analysis of the market trends in each of the ...
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SODIUM ALGINATE is part of manufacturing ingredient used in FDA Database. When you consume you prescription drug make sure that you are not allergic to this SODIUM ALGINATE. This will change the way your body absorbs prescription drug your doctor provided you with. SODIUM ALGINATE is used in manufacturing process of pharmaceutical products. List bellow has SODIUM ALGINATE as ingredient during manufacturing.. As some Prescription Drugs might have same name but they are classified by FDA with uniq ID.. ...
This review provides a critical update on human and animal studies investigating the effect of alginate supplementation on appetite regulation, glycaemic and insulinemic responses, and lipid metabolism with discussion of the evidence on potential mechanisms, efficacy and tolerability. Dependent on vehicle applied for alginate supplementation, the majority of animal and human studies suggest that alginate consumption does suppress satiety and to some extent energy intake. Only one long-term intervention trial found effects on weight loss. In addition, alginates seem to exhibit beneficial influence on postprandial glucose absorption and insulin response in animals and humans. However, alginate supplementation was only found to have cholesterol-lowering properties in animals. Several mechanisms have been suggested for the positive effect observed, which involve delayed gastric emptying, increased viscosity of digesta and slowed nutrient absorption in the small intestine upon alginate gel formation. ...
Alginate hydrogel made from alginate and crosslinking divalent ions is a natural biomaterial that is biocompatible, has low toxicity, is relatively cheap and has mild gelation chemistry. It is a porous material that allows diffusion of small molecules. Alginate hydrogel is a polymeric network that contains 95-99% water and it does in many ways resemble the natural extracellular matrix (ECM) that surrounds cells in the body. It is also hydrophilic, which reduces friction in body fluids and minimizes protein adsorption and it is easily stored and sterilized.Alginate is produced by both algae and bacteria, and it is initially synthesized as mannuronan (M) with 100% M-residues. Guluronic acid residues (G) are introduced in a post-polymerization step by enzymes called mannuronan C-5 epimerases that catalyze conversion of M into G without breaking the glycosidic bond. Seven different mannuronan C-5 epimerases have been sequenced, cloned and produced recombinantly, and these enzymes introduce ...
Here, we sought to develop a cell culture surface conversion technique that would not damage living cells. An alginate thin film, formed on a glass plate by spin coating of sodium alginate solution and dipping into calcium chloride solution, was used to inhibit adhesion of cells. The film could be removed by ethylenediaminetetraacetate (EDTA) at any time during cell culture, permitting observation of cellular responses to conversion of the culture surface in real time. Additionally, we demonstrated the validity of the alginate thin film coating method and the performance of the film. The thickness of the alginate thin film was controlled by varying the rotation speed during spin coating. Moreover, the alginate thin film completely inhibited the adhesion of cultured cells to the culture surface, irrespective of the thickness of the film. When the alginate thin film was removed from the culture surface by EDTA, the cultured cells adhered to the culture surface, and their morphology changed. ...
The two-phase model used previously to calculate the polymer-subphase volume of alginic acid was applied to interpret the dependence of apparent metal binding equilibrium on environmental conditions. In this model, the polymer subphase, a small aqueous region surrounding the polymer chain, was considered as a separate phase in the aqueous solution and as a protonation-deprotonation and metal binding reaction zone. Three factors were taken into account when treating experimental data: (1) the electric field due to the charged ligands on the polymer molecule, (2) the effective concentration of ligands based on polymer-subphase volume, and (3) the competition from hydrogen ions for the metal binding sites. The data of base titration of alginic acid in the presence of trace amounts of copper at different alginic acid concentrations and ionic strengths yielded unique intrinsic stability constants for complexes formed between a cupric ion and one or two binding ligands ...
Dolomite Microfluidics systems are enabling reliable, reproducible production of monodisperse alginate beads, overcoming the challenges associated with traditional batch techniques. Controlled and reproducible generation of alginate gel beads is crucial for biomedical science and engineering applications that require biologically and chemically inert polymers, such as the encapsulation of drugs or cells. However, this can be difficult to achieve with batch synthesis, which produces large beads with a wide size distribution and minimal control over bead size. The reproducibility and throughput of the technique are also low. Microfluidic synthesis of alginate beads overcomes these difficulties, allowing precise control of bead formation and enabling rapid production of particles with well-defined sizes, shapes and morphologies ...
Alginic acid, also called algin or alginate, is an anionic polysaccharide distributed widely in the cell walls of brown algae, where through binding with water it forms a viscous gum. It is also a significant component of the biofilms produced by the bacterium Pseudomonas aeruginosa, the major pathogen in cystic fibrosis, that confer it a high resistance to antibiotics and killing by macrophages. Its colour ranges from white to yellowish-brown. It is sold in filamentous, granular or powdered forms. Alginic acid is a linear copolymer with homopolymeric blocks of (1-4)-linked β-D-mannuronate (M) and its C-5 epimer α-L-guluronate (G) residues, respectively, covalently linked together in different sequences or blocks. The monomers can appear in homopolymeric blocks of consecutive G-residues (G-blocks), consecutive M-residues (M-blocks) or alternating M and G-residues (MG-blocks). Alginates are refined from brown seaweeds. A wide variety of brown seaweeds of the phylum Phaeophyceae are harvested ...
Sodium alginate is a seaweed-derived fibre that has previously been shown to moderate appetite in models of acute feeding. The mechanisms underlying this effect may include slowed gastric clearance and attenuated uptake from the small intestine. In order to assess whether alginate could be effective as a means of appetite control in free-living adults, 68 males and females (BMI range: 18.50-32.81 kgl M-2) completed this randomised, controlled two-way crossover intervention to compare the effects of 7 day daily ingestion of a strong-gelling sodium alginate formulation against a control. A sodium alginate with a high-guluronate content was chosen because, upon ingestion, it forms a strong gel in the presence of calcium ions. Daily preprandial ingestion of the sodium alginate formulation produced a significant 134.8 kcal (7%) reduction in mean daily energy intake. This reduced energy intake was underwritten by significant reductions in mean daily carbohydrate, sugar, fat, saturated fat and protein ...
Alginate can be produced by a microbial fermentation using bacteria such as Azobacter Vinelandii and Pseudomonas Aeruginosa (Linker and Jones 1964, Gorin and Spencer 1966). These bacteria produce a polysaccharide with a structure resembling alginate, differing only in that there are acetyl groups on a portion of the C2 and C3 hydroxyls. It is believed that the acetate groups are associated mainly with the D-mannuronic acid residues (Davidson 1977, Sutherland 1983, Paul 1986). The level of acetylation is variable as is the mannuronic and guluronic acid content. However the level of guluronic acid in the final polymer can be controlled to some extent by altering the level of calcium in the fermentation broth (Haug and Larsen 1971). The sequence structures and acetylation patterns of bacterial alginate, from different sources, have been studied with 2D COSY proton NMR techniques. The acetyl residues were found to be exclusively associated with the mannuronic acid residues with degrees of ...
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TY - JOUR. T1 - Gypsum Compatibility of Antimicrobial Alginates After Spray Disinfection. AU - King, Barbara B.. AU - Norling, Barry K.. AU - Seals, Richard. PY - 1994/12. Y1 - 1994/12. N2 - This investigation examined the gypsum compatibility of two antimicrobial alginates after spray disinfection. Subjective compatibility evaluations were compared with objective quantitative profilometer readings of gypsum cast surface roughness. COE Hydrophilic Gel Alginate, Jeltrate Plus Antimicrobial Alginate, and their nonantimicrobial counterparts, Coe Alginate and Jeltrate Plus, were used in this study. After spray disinfection with water (control), Alcide LD, Biocide, OMC II, and 0.5% NaOCl, impressions of the American National Standards Institute/American Dental Association (ANSI/ADA) specification no. 18 detail reproduction die and impressions made simultaneously of a smooth glass die were cast in Microstone, Silky‐Rock, and Die‐Keen. Five specimens were made for each alginate/disinfectant/gypsum ...
Pseudomonas aeruginosa (PA) infections in Cystic Fibrosis (CF) patients are not easily cleared due to the conversion from a nonmucoid to a mucoid phenotype. Alginate is an acetylated exopolysaccharide produced by mucoid PA that is responsible for increased resistance to antibiotics, host phagocytic killing, and propagating biofilm formation. Understanding the interaction between PA and host cells is critical to understanding chronic infection and inflammation in CF. In order to investigate this, we used A549 pulmonary epithelial cells and murine alveolar macrophages (MH-S) to examine host response to nonmucoid versus mucoid PA infection. Adhesion assays in A549 pulmonary epithelial cells revealed that mucoid PA mutants adhere poorly compared to their nonmucoid counterparts. Similarly, phagocytosis assays using MH-S infected with PA revealed that mucoid PA are increasingly resistant to phagocytosis. The alginate acetylation mutant FRD1175 is more susceptible to phagocytic killing than alginate+ FRD1.
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Sodium Alginate (alginate, algin) Molecular RecipesSodium Alginate is a natural polysaccharide product extracted from brown seaweed that grows in cold water regions. In modernist cuisine, sodiu&thickener sodium alginate
... (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E ... Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are ... a b Propylene glycol alginate, Food and Agriculture Organization of the United Nations ... What is the "propylene glycol alginate" found in salad dressings? at The Straight Dope ...
... is also used for the production of alginates, with China producing up to ten thousand tons of the product ... "Alginates". Miyai, Kiyoshi; Tokushige, Tomoyasu; Kondo, Masahiko (2008-12-01). "Suppression of thyroid function ...
Alginate seaweed sources Alginate properties Alginate medical uses article Wired on Easy Cheese, describing sodium alginate. ... Sodium alginate (NaC6H7O6) is the sodium salt of alginic acid. Sodium alginate is a gum. Potassium alginate (KC6H7O6 ) is the ... Sodium alginate is mixed with soybean flour to make meat analogue.[citation needed] Alginate is used as an ingredient in ... Calcium alginate (C12H14CaO12 ), is made from sodium alginate from which the sodium ion has been removed and replaced with ...
ISBN 978-1-4398-4887-6.CS1 maint: extra text: authors list (link) editor, Bernd H. A. Rehm (2009). Alginates biology and ...
Sodium alginate • Soft palate • SoftDent • SOHP • Sonicare • Southern Regional Testing Agency • Sozodont • Speech organ • ... Potassium alginate • Premolar • Preparation • Primordial cyst • Procaine • Procter & Gamble • Prognathism • Prosthodontics • ...
Alginates can be extracted from L. hyperborea. In France, Ireland, Scotland and Norway, stipes cast up on beaches are collected ...
Alginates can be used as thickening agents. Although listed here under the category 'Microbial polysaccharides', commercial ... ISBN 978-1-904455-36-3. Remminghorst & Rehm (2009). "Microbial Production of Alginate: Biosynthesis and Applications". ... alginates are currently only produced by extraction from brown seaweeds such as Laminaria hyperborea or L. japonica. Poly-γ- ...
Alginate dressings: these dressings are composed of calcium, sodium salts and also provide a moist environment for the healing ... Hydro-fiber dressings: these dressings are similar to alginate dressings when it comes to absorbing characteristics, but they ... alginate dressings, hydrofiber dressings, transparent film dressings, hydrogel dressings, and hydrocolloid dressings. All of ...
Hydrogel alginates have emerged as one of the most commonly used materials in organ printing research, as they are highly ... For instance, alginate polymerization is started by calcium ions in the substrate, which diffuse into the liquified bioink and ... Alginate hydrogel that is suitable for extrusion printing is also often less structurally and mechanically sound; however, this ... A major challenge in the use of alginate is its stability and slow degradation, which makes it difficult for the artificial gel ...
"Small-Angle X-Ray Scattering and Rheological Characterization of Alginate Gels. 1. Ca−Alginate Gels". Macromolecules. 33 (5): ...
Alginic acids (Alginates). E 400-E 407. in Algae Sodium alginate. E 401 ...
Sodium alginate is an unbranched copolymer of 1,4-linked-β-d-mannuronate (M) and α-l-guluronate (G) sugars. Sodium alginate ( ... Alginates are the natural product of brown algae and have been used extensively in wound dressing, drug delivery and tissue ... "CALCIUM ALGINATE - National Library of Medicine HSDB Database". Archived from the original on 2017-11-15. ... Chiu, Chih-Tung; Lee, Jui-Sheng; Chu, Chi-Shung; Chang, Yi-Pin; Wang, Yng-Jiin (2008-02-12). "Development of two alginate-based ...
2017 Jun 22;6:CD011947 Dumville JC, Keogh SJ, Liu Z, Stubbs N, Walker RM, Fortnam M (May 2015). "Alginate dressings for ... Cochrane reviews summarise evidence on alginate dressings, foam dressings, and hydrogel dressings. Due to a lack of robust ...
... sodium alginate and ulva (ID 1873); vitamins, minerals, trace elements and standardised ginseng G115 extract (ID". EFSA Journal ...
There is uncertain evidence whether alginate dressing is effective in the healing of venous ulcer when compared to hydrocolloid ... Cochrane Wounds Group) (August 2015). "Alginate dressings for venous leg ulcers". The Cochrane Database of Systematic Reviews ( ...
... sodium alginate and ulva (ID 1873); vitamins, minerals, trace elements and standardised ginseng G115 extract (ID 8, 1673, 1674 ...
Qin Y (June 2005). "Silver-containing alginate fibres and dressings". International Wound Journal. 2 (2): 172-6. doi:10.1111/j. ...
The amount of free calcium ions needs to be sufficient in order to form a gel-like capsule reaction with sodium alginate. Milk ... When the liquid containing alcohol or calcium salt is dropped into an alginate bath, the liquid will draw itself into a ... Both the liquid for consumption and the alginate bath should be left to stand after preparing to eliminate air bubbles. Air ... After removing the jelly from the alginate bath, calcium would not continue to diffuse into the center of the sphere, therefore ...
Cheshire, Anthony C.; Hallam, Neil D. (1985). "The environmental role of alginates in Durvillaea potatorum (Fucales, Phaeophyta ...
Their cell walls are composed of alginate. They use laminarin and mannitol for storage. Like most brown algae, Postelsia goes ...
Dumville JC, O'Meara S, Deshpande S, Speak K (June 2013). "Alginate dressings for healing diabetic foot ulcers". The Cochrane ... Dressings and creams containing silver have not been properly studied nor have alginate dressings. Biologically active bandages ...
Alginates are used in wound dressings (see alginate dressing), and dental moulds. In microbiology, agar is used as a culture ... Alginates are used in industrial products such as paper coatings, adhesives, dyes, gels, explosives and in processes such as ... Carrageenans, alginates and agaroses, with other macroalgal polysaccharides, have biomedicine applications. Delisea pulchra may ... " ("sweet"). Alginate, agar and carrageenan are gelatinous seaweed products collectively known as hydrocolloids or ...
Qin Y (2005). "Silver-containing alginate fibres and dressings". Int Wound J. 2 (2): 172-6. doi:10.1111/j.1742-4801.2005.00101. ... Dumville, JC; O'Meara, S; Deshpande, S; Speak, K (25 June 2013). "Alginate dressings for healing diabetic foot ulcers". The ... A 2012 Cochrane review found that silver-containing hydrocolloid dressings were no better than standard alginate dressings in ...
Collogel dispersed sodium alginate in domestic water systems. Two years later the company introduced Adjunct for use in ...
"ThiolEne Alginate Hydrogels as Versatile Bioinks for Bioprinting". doi:10.1021/acs.biomac.8b00696.s001. Cite journal requires , ...
Hecht, Hadas; Srebnik, Simcha (2016). "Structural Characterization of Sodium Alginate and Calcium Alginate". Biomacromolecules ... For example, sodium alginate gels upon exposure to calcium ion, which allows it to form ionic bonds that bridge between ... alginate chains. Polyvinyl alcohol gels upon the addition of borax through hydrogen bonding between boric acid and the ...
... alginate) and minerals (hydroxyapatite). Alginate scaffolds, composed of cross-linked calcium ions, are actively being explored ... Alginate's ability to scaffold and makes it a novel polysaccharide. Even though many minerals can be adapted for bone ... Uses for alginate in composites include chitosan composites for bone tissue repair, bioglass composites for repairing or ... Other composites suitable for use in artificial bone are those using alginate, a biopolymer known for its scaffold-forming ...
Alginate Alginate is an important role in the development of antimicrobial textiles due to its characteristics of environmental ... Li, J., He, J., & Huang, Y. (2017). Role of alginate in antibacterial finishing of textiles. ...
The multivalent ions used to create the alginate-based ACH gels were copper ions, whose diffusion into the sodium alginate ... Alginate is a polysaccharide that readily forms chains; it can be cross-linked at its carboxylic groups with multivalent ... Calcium alginates form polymers that are both biocompatible and non-immunogenic and have been used in tissue engineering ... The capillary walls are lined with the precipitated metal alginate, while the lumen is filled with the extruded water. Prang et ...
nov., an alginate-degrading bacterium isolated from a microbial consortium". International Journal of Systematic and ... Dysgonomonas alginatilytica has the ability to degrade alginate. Parte, A.C. "Dysgonomonas". LPSN. "Dysgonomonas alginatilytica ...
Propylene glycol alginate (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E ... Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are ... a b Propylene glycol alginate, Food and Agriculture Organization of the United Nations ... What is the "propylene glycol alginate" found in salad dressings? at The Straight Dope ...
1,2-propane-diol ester of alginic acid; hydroxypropyl alginate; propane 1,2-diol alginate; INS No. 405. ... Propylene glycol alginate. Prepared at the 49th JECFA (1997). superseding specifications prepared at the 44th JECFA (1995),. ... Propylene glycol alginate is an ester of alginic acid in which some of the carboxyl groups are esterified with propylene glycol ...
Role of the Pseudomonas fluorescens Alginate Lyase (AlgL) in Clearing the Periplasm of Alginates Not Exported to the ... Role of Alginate and Its O Acetylation in Formation of Pseudomonas aeruginosa Microcolonies and Biofilms David E. Nivens, ... Alginate Overproduction Affects Pseudomonas aeruginosa Biofilm Structure and Function Morten Hentzer, Gail M. Teitzel, Grant J ... MucA-Mediated Coordination of Type III Secretion and Alginate Synthesis in Pseudomonas aeruginosa Weihui Wu, Hassan Badrane, ...
This new volume explores the latest research on the use of alginate as a biopolymer in various biomedical applications and ... The uses of alginates and modified alginates discussed in this book include tissue regeneration, encapsulation and delivery of ... This book also describes the synthesis and characterizations of various alginate and modified alginate systems, such as ... Updates on Alginate-Based Interpenetrating Polymer Networks for Sustained Drug Release. Ibrahim M. El-Sherbiny and Kholoud ...
Calcium alginate can be produced from a sodium alginate solution by the addition of a calcium salt such as calcium chloride. ... Calcium alginate is also used for entrapment of enzymes and forming artificial seeds in plant tissue culture. "Alginate" is ... This influences the alginates physical and chemical properties. Uses of calcium alginate are: in plant tissue culture to ... Over a period of about two hours, the alginate dissolves as sodium alginate to give a very thick slurry. This slurry also ...
... alginate)n+1 Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP ... In enzymology, an alginate synthase (EC is an enzyme that catalyzes the chemical reaction GDP-D-mannuronate + ( ... The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. This enzyme is also called ... and (alginate)n+1. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. ...
alginate synonyms, alginate pronunciation, alginate translation, English dictionary definition of alginate. n. A salt of ... alginate. Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.. Related to alginate: sodium alginate ... Our objective was to evaluate alginate and alginate-chitosan as encapsulating polymers for glycerol.. Evaluation of glycerol ... Suo and co-workers developed highly stretchable, tough alginate/PAM hybrid DN hydrogels with alginate network ionically ...
Alginates is made up of long chains of two monomers -- guluronic acid and manuronic acid. The chains can be made of all one ... Alginates are used as thickeners in fat substitutes, pet food, stuffed olives, onion rings, low fat sauces and spreads, and pie ... It also makes alginates useful as wound dressings, where they absorb fluids, and stop bleeding, and act as a scaffold. ... Propylene glycol alginate is stable in acids, and is used to keep the foamy head on beers. ...
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Restore Calcium Alginate Dressing is a high absorption dressing for highly exuding wounds. Restore Calcium Alginate Dressing ... Restore Calcium Alginate Dressing dressing can be removed in one piece. ... Restore SILVER Calcium Alginate Dressing. Restore SILVER Calcium Alginate Dressing releases silver ions in the presence of ... Restore SILVER Calcium Alginate Dressing - Sterile is also listed in these categories below:. / Wound Care. / Wound Dressings ...
Pseudomonas aeruginosa synthesizes an exopolysaccharide called alginate in response to environmental conditions. Alginate ... Transcription of the alginate biosynthetic genes is induced upon attachment to the substratum and this leads to increased ... Thus, both alginate biosynthetic and degradative enzymes are important for the development, maintenance and spread of P. ... This negates the anchoring properties of the alginate and results in increased detachment of the bacteria away from the surface ...
Characterization of Alginate Characterization of sodium alginate was conducted to determine the physical and chemical ... by drying the sample at 105 oC alginate. The water content is determined based on the dry weight alginate that is a percentage ... Alginate ash content expressed as a percentage by weight of ash to the dry sample weight. Analysis of Pb and Hg Determination ... Then converted to sodium alginate by adding 20 g of Na2CO3 and stirred in a mixer. The resulting solution is then etched with ...
The investigators will use alginate, in the form of alginate beads, as a protective barrier for soluble iron gluconate. It has ... iron gluconate incorporated into alginate beads,ferrous gluconate incorporated into alginate beads given with calcium, and ... Dietary Supplement: alginate beads with ferrous gluconate in presence of calcium After insertion of the cannula and collection ... Alginate inhibits iron absorption from ferrous gluconate in a randomized controlled trial and reduces iron uptake into Caco-2 ...
Heres some pictures and a video of my first experiments with sodium alginate and spherification. I used sodium alginate from ... Sodium alginate is water soluble and can be mixed with many different fruit/vegetable juices and purés. When dripped into a ... When alginate is coordinated to sodium, its a very flexible chain. When sodium is replaced by calcium however, each calcium ... Chef Simon (French, click here for babelfish translation) has a nice page on alginates as well. Another french page here (with ...
Alginates isolated from certain types of seaweed may have potential in weight loss supplements and foods, according to new ... The team used bread as a vehicle for the delivery of the alginate a further during trial - finding that even a small amount ... "Method for quantifying alginate and determining release from a food vehicle in gastrointestinal digesta"​. Authors: David ... The study, published in Food Chemistry​, shows that alginate from sea kelp can suppress the digestion of fat in the gut - ...
Exploring Fabrication - Gummy Capsules" lets visitors make self-assembled polymer spheres. They learn that self-assembly is a process by which molecules and cells form themselves into functional structures, and that self-assembly is used to make nanocapsules that can deliver medication ...
2005) Role of an alginate lyase for alginate transport in mucoid Pseudomonas aeruginosa. Infect Immun 73:6429-6436. ... 2006) In vitro alginate polymerization and the functional role of Alg8 in alginate production by Pseudomonas aeruginosa. Appl ... 2005) Role of the Pseudomonas fluorescens alginate lyase (AlgL) in clearing the periplasm of alginates not exported to the ... Structural basis for alginate secretion across the bacterial outer membrane. John C. Whitney, Iain D. Hay, Canhui Li, Paul D. W ...
A list of US medications equivalent to Alginate de sodium/Bicarbonate de sodium Mylan is available on the website. ... Alginate de sodium/Bicarbonate de sodium Mylan is a medicine available in a number of countries worldwide. ... Ingredient matches for Alginate de sodium/Bicarbonate de sodium Mylan. Sodium Alginate. Sodium Alginate is reported as an ... Alginate de sodium/Bicarbonate de sodium Mylan. Alginate de sodium/Bicarbonate de sodium Mylan may be available in the ...
Alginates in the Snack and wholesale bakery industry, which includes food processing and packaging equipment as well as ... Home » Directories » Buyers Guide » Gums, Vegetable Alginates. Buyers Guide. Directory & Buying Guide. * Construction, ... Companies in Gums, Vegetable Alginates DuPont Nutrition & Biosciences DuPont Nutrition & Biosciences delivers essential food ...
Micrometre-sized silver flakes are suspended in a polyacrylamide-alginate hydrogel matrix and, after going through a partial ... A hydrogel composite that consists of micrometre-sized silver flakes suspended in a polyacrylamide-alginate hydrogel matrix ... Strengthening alginate/polyacrylamide hydrogels using various multivalent cations. ACS Appl. Mater. Interfaces 5, 10418-10422 ( ... Ohm, Y., Pan, C., Ford, M.J. et al. An electrically conductive silver-polyacrylamide-alginate hydrogel composite for soft ...
... alginate dressings are designed to interact with sodium in wounds to create an ionic exchange and help jump-start the ... Alginate Dressings. Kendall™ alginate dressings are designed to interact with sodium in wounds to create an ionic exchange and ... Kendall™ Calcium Alginate Dressings. Kendall™ calcium alginate dressings are designed to interact with sodium in wounds to ... Kendall™ Zinc Calcium Alginate Dressings. Kendall™ zinc calcium alginate dressings are designed to interact with sodium in ...
Due to the coronavirus outbreak worldwide, global demand for some personal protective equipment (PPE) is exceeding supply. In addition, manufacturing of PPE and many other wound care and infection prevention products have been impacted by global response to coronavirus. While you may see product availability reduction in the near-term, please be assured Medline continues to work to diversify production and provide your supply needs. As always, please reach out to your Medline sales representative with any specific questions or follow up. ...
Get the best prices on Calcium Alginate Dressing, Silver Alginate Wound Dressing and more at Allegro Medical. ... Alginate Dressings - Calcium Alginate Dressings - Silver Alginate Wound Dressing. Alginate dressings are a popular type of ... At Allegro Medical, you will find many different options for these alginate dressings, including rope dressings and ... Fibracol Plus Collagen Wound Dressing with Alginate - 3/ 8 x 15- 3/4... ...
... Liqiang Wang,1,2 Osvaldo Campanella,3 Bhavesh Patel, ... Liqiang Wang, Osvaldo Campanella, Bhavesh Patel, and Lixin Lu, "Preparation and Sealing Processing of Sodium Alginate Based ...
Sodium alginate, SCMC, and gelatin powders were weighed and mixed to get total weight of 4.5 g (3.0 : 1.0 : 0.5 ratio) and ... Preparation and Sealing Processing of Sodium Alginate Based Blending Film. Liqiang Wang,1,2 Osvaldo Campanella,3 Bhavesh Patel, ... Sodium alginate was purchased from TIC Gums, Inc. (MD, USA), sodium carboxymethyl cellulose (type 7MF) was obtained from ... M. S. Tapia, M. A. Rojas-Graü, F. J. Rodríguez, J. Ramírez, A. Carmona, and O. Martin-Belloso, "Alginate- and gellan-based ...
Scalable Preparation of Alginate Templated-Layered Double Hydroxide Mesoporous Composites with Enhanced Surface Areas and ... Here we report on a scalable preparation of sodium alginate-templated MgAl-LDH (LDH/SA) mesoporous composites with high surface ... The powdery LDH/SA mesoporous composites are prepared using alginate as template by a scalable method of separate nucleation ... Keywords: LAYERED DOUBLE HYDROXIDES; MESOPOROUS COMPOSITES; SODIUM ALGINATE; SURFACE ACTIVITY; SURFACE AREA ...
DuPont to sell existing alginates business. DuPont to divest alginates business as Commission clears FMC-DuPont deals. By ... Alginates are used as stabilising, thickening or gelling agents in both food and pharmaceutical products. ... In addition to DuPonts sell-off of its alginate business, clearance of the proposed acquisition of DuPonts crop protection ... The conditional clearance of the DuPont-FMC swap deal, based on the above additional divestments of alginates and herbicides ...
Next Generation Science Standards and NGSS are registered trademarks of Achieve. Neither Achieve nor the lead states and partners that developed the Next Generation Science Standards were involved in the production of this product, and do not endorse it.. ...
  • What is the "propylene glycol alginate" found in salad dressings? (
  • Uses of calcium alginate are: in plant tissue culture to produce insoluble artificial seeds for immobilizing enzymes by entrapment to produce an edible substance incorporated into wound dressings (alginate dressings) as a hemostatic as a alginate hydrogel, can be used for a controlled-release drug delivery system Gosselin, R.E. (
  • DEHYDRATED HUMAN umbilical cord allograft may have benefit over alginate wound dressings as a treatment for chronic, nonhealing diabetic foot ulcers (DFU), findings from an industry-funded, randomized controlled study suggest. (
  • It also makes alginates useful as wound dressings, where they absorb fluids, and stop bleeding, and act as a scaffold. (
  • Kendall™ alginate dressings are designed to interact with sodium in wounds to create an ionic exchange and help jump-start the epitheliazation process. (
  • Alginate dressings for healing diabetic foot ulcers. (
  • Dressings form a key part of ulcer treatment, with clinicians and patients having many different types to choose from including alginate dressings. (
  • To compare the effects of alginate wound dressings with no wound dressing or alternative dressings on the healing of foot ulcers in people with diabetes mellitus. (
  • Published or unpublished randomised controlled trials (RCTs) that have compared the effects on ulcer healing of alginate dressings with alternative wound dressings or no dressing in the treatment of foot ulcers in people with diabetes. (
  • these compared alginate dressings with basic wound contact dressings, foam dressings and a silver-containing, fibrous-hydrocolloid dressing. (
  • Meta analysis of two studies found no statistically significant difference between alginate dressings and basic wound contact dressings: risk ratio (RR) 1.09 (95% CI 0.66 to 1.80). (
  • Pooled data from two studies comparing alginate dressings with foam dressings found no statistically significant difference in ulcer healing (RR 0.67, 95% CI 0.41 to 1.08). (
  • Currently there is no research evidence to suggest that alginate wound dressings are more effective in healing foot ulcers in people with diabetes than other types of dressing however many trials in this field are very small. (
  • TY - JOUR T1 - Alginate dressings for healing diabetic foot ulcers. (
  • Alginates are used as foam, clotting agents and gauze in absorbable surgical dressings and packing. (
  • Alginate dressings are derived from seaweed made of soft non-woven fibres, and are available as pads, ropes or ribbons. (
  • Alginate dressings are extremely lightweight, absorb many times their own weight, form a gel-like covering over the wound, and maintain a moist environment. (
  • used, in the form of calcium, sodium or ammonium alginate, as foam, clot or gauze for absorbable surgical dressings. (
  • Provides not only superior absorbency, but also superior wet strength when compared with other calcium alginate dressings tested. (
  • Contrary to hydrofiber dressings, Biatain Alginate Ag has documented haemostatic effect, i.e. ability to arrest blood flow in minor bleedings. (
  • Mayonnaise and salad dressings thickened with sodium alginate are less likely to separate into their original oil and water forms. (
  • These images are a random sampling from a Bing search on the term "Alginate Dressing. (
  • CURASORB Calcium Alginate Dressing - 4 x. (
  • Abena® Calcium Alginate Dressing with Si. (
  • Abena® Calcium Alginate Dressing, Steril. (
  • Restore SILVER Calcium Alginate Dressing releases silver ions in the presence of wound exudate. (
  • SILVERCEL Antimicrobial Alginate Dressing - 4 1/ 4' x 4 1/ 4' Square P. (
  • CM Alginate is a soft, highly absorbent dressing that quickly forms a hydrophilic gel and cover the wound bed. (
  • Melgisorb Ag is a highly absorbent alginate dressing with CMC and ionic silver that kills bacteria for up to four days. (
  • The superb, wet strength of these alginate fibers do not allow the dressing to disintegrate in the wound bed so it may be removed easily in one piece. (
  • There was no statistically significant difference in the number of diabetic foot ulcers healed when an anti-microbial (silver) hydrocolloid dressing was compared with a standard alginate dressing (RR 1.40, 95% CI 0.79 to 2.47). (
  • SILVERCEL Dressing is a sterile, non-woven pad composed of high tensile strength alginate, carboxymethylcellulose (CMC) and silver coated nylon fibers. (
  • CURASORB Calcium Alginate Dressing Absorbs exudate from wound, creating a protective gel and moist healing environment. (
  • ALGISITE M is a calcium-alginate dressing which forms a soft, gel that absorbs when it comes into contact with wound exudate. (
  • 3M™ Tegaderm™ Alginate Ag Silver Dressing highly absorbent, antimicrobial wound dressing with an ionic silver complex to provide antimicrobial protection. (
  • Propylene glycol alginate has widespread application such as thickening agent used in ice creams, salad dressing, and foam stabiliser especially used in brewery industries and widely used as food preservatives. (
  • Biatain Alginate Ag is a highly absorbent silver alginate dressing for moderately to heavily exuding infected wounds of any size, shape and depth. (
  • Biatain Alginate Ag is an alginate dressing consisting of calcium alginate, carboxymethylcellulose (CMC) and an ionic silver complex. (
  • Human neutrophil elastase inhibition with a novel cotton-alginate wound dressing formulation. (
  • Occlusion and elasticity were combined in a novel cotton-based alginate dressing containing a nontoxic elastase inhibitor. (
  • Cotton gauzes were modified with a textile finishing process for incorporating alginate to yield a dressing material that retains elasticity while enhancing absorption. (
  • AlgiSite M Calcium Alginate Dressing creates and maintains a moist healing environment, enabling epithelial cells to migrate freely across the wound surface. (
  • AlgiSite M, Calcium Alginate dressing is used to manage partial- and full-thickness wounds with moderate to heavy exudate, such as leg ulcers, pressure ulcers (stages 3 & 4), diabetic foot ulcers, and surgical wounds. (
  • Buy Smith and Nephew AlgiSite M Calcium Alginate Dressing online from a set aside SDVOSB Service-Disabled Veteran-Owned Small Business medical supplies company like Mountainside Medical Equipment that is certified with the United States Government. (
  • The resulting solution is then etched with ethanol to form sodium alginate fibers. (
  • All fiber based alginates release fibers when handled, however the advanced bonding technique employed in ALGISITE M greatly reduces this. (
  • The production of a gel by the action of exudate on the alginate fibers creates a moist wound environment at the wound surface. (
  • Use Sodium Alginate SH for cotton and other cellulose fibers. (
  • 12. The method of claim 1 further comprising treating the plurality of alginate fibers with an ionic crosslinking agent to provide a plurality of ionically crosslinked alginate fibers. (
  • Another use of sodium alginate is to form films of sodium or calcium alginate, and fibers of calcium alginates. (
  • The alginate-citrate finishes were combined with the neutrophil elastase inhibitor, oleic acid, to demonstrate the ability of the algino-cellulose fibers to release the inhibitor and neutralize destructively high levels of neutrophil elastase found in nonhealing and burn wounds. (
  • Scanning electron microscopy analysis revealed large areas of the yarn surface covered by the alginate film with a smooth surface on the original fibers. (
  • Produces a gel on contact with the alginate fibers to maintain a moist wound surface environment. (
  • Chemically, propylene glycol alginate is an ester of alginic acid , which is derived from kelp . (
  • Propylene glycol alginate is an ester of alginic acid in which some of the carboxyl groups are esterified with propylene glycol, some neutralized with an appropriate alkali and some remain free. (
  • Alginate is present in the cell walls of brown algae, as the calcium, magnesium and sodium salts of alginic acid. (
  • An acid is added to isolate the alginic acid from the diluted sodium alginate solution. (
  • n a salt of alginic acid (e.g., sodium alginate), which, when mixed with water in accurate proportions, forms an irreversible hydrocolloid gel used for making impressions or molds of the denti-tion. (
  • Alginates are salts of alginic acid taking the form of sodium, calcium and/or ammonium alginate precipitated from brown seaweed (algae).The global alginates and derivatives market is projected to reach a value of $409.2 million by 2019 growing at a CAGR of 3.8% from 2014 to 2019. (
  • Propylene glycol alginate is chemical combination of alginic acid and propylene oxide. (
  • Principally, propylene glycol alginate is derivative of alginic acid ester, which is obtained from kelp plant. (
  • 6. An isolated protein comprising an enzymatically active alginate lyase sequence having a thermostable alginate lyase activity. (
  • The global alginates & derivatives market is projected to reach a value of $409.2 million by 2019 growing at a CAGR of 3.8% from 2014 to 2019. (
  • The market value of alginates was estimated at US$ 379 million in 2019 and is expected to increase at a CAGR rate of 4.1% to US$ 458 million by 2024. (
  • New York, NY -- ( SBWIRE ) -- 04/30/2019 -- There are several types of alginates available in the global market including sodium, calcium, and potassium out of which sodium alginates hold the highest share of the market. (
  • Micrometre-sized silver flakes are suspended in a polyacrylamide-alginate hydrogel matrix and, after going through a partial dehydration process, the flakes form percolating networks that are electrically conductive and robust to mechanical deformations. (
  • A tunable silk-alginate hydrogel scaffold for stem cell culture and transplantation. (
  • This paper reports the development of a new silk-alginate based hydrogel with a focus on stem cell culture. (
  • The multifunctional anticancer-drug carrier bead was fabricated by incorporating functional nanomaterials, such as near-infrared (NIR)-responsive gold nanorod (GNR) and superparamagnetic iron oxide nanoparticles (IONP) that work as a magnetic resonance imaging (MRI) contrast agent, into an alginate hydrogel bead. (
  • Real-time in-situ Rheology of Alginate Hydrogel Photocrosslinking. (
  • This video describes how an alginate hydrogel can be used to trigger the formation of new blood vessels at an ischemic site in the body. (
  • Hydrogel ® Mold Compound is an alginate-based white powder that, after mixing with water, cures in 5 minutes to a moist, rubbery material. (
  • Pseudomonas aeruginosa biofilms: role of the alginate exopolysaccharide. (
  • Pseudomonas aeruginosa synthesizes an exopolysaccharide called alginate in response to environmental conditions. (
  • During colonization of the lung, P. aeruginosa converts to a mucoid phenotype characterized by the overproduction of the exopolysaccharide alginate. (
  • Mucoidy is a descriptive term for the production of copious amounts of the exopolysaccharide alginate, a phenotype that appears to be selected by the environment of the CF lung ( 3 ). (
  • A major component of the biofilm during these infections is the exopolysaccharide alginate, which is synthesized at the inner membrane as a homopolymer of 1-4-linked β-D-mannuronate. (
  • Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation. (
  • During the course of chronic cystic fibrosis (CF) infections, Pseudomonas aeruginosa undergoes a conversion to a mucoid phenotype, which is characterized by overproduction of the exopolysaccharide alginate. (
  • The mucoid phenotype is caused by overproduction of alginate, an exopolysaccharide (EPS) consisting of mannuronic acid and guluronic acid monomers. (
  • Sodium alginate is water soluble and can be mixed with many different fruit/vegetable juices and purés. (
  • To extract the alginate in the seaweed caustic soda is added to convert the seaweed to water-soluble sodium alginate. (
  • water-soluble alginates are useful as materials for dental impressions. (
  • The copolymer consists of two uronic acids: D-mannuronic acid (M) and L-guluronic acid (G ). Sodium alginate as well as other alkali metal alginates are water soluble, whereas the salts of polyvalent cations, e.g., calcium, nickel, copper, cobalt are water insoluble, with the exception of magnesium. (
  • Provides the broad-spectrum antimicrobial action of silver with enhanced exudate management properties of alginate technology. (
  • Curcumin loaded alginate foams are proposed for application in antimicrobial photodynamic therapy of infected wounds. (
  • Biatain Alginate Ag provides continuous antimicrobial effect during the entire wear time (up to 7 days). (
  • Persistence Market Research (PMR) recently published a well-researched study about the growth of the global sodium alginate market. (
  • The study also offers valid reasoning and explanation on the how the revenue share was estimated for each segment of the global sodium alginate market, which can help market players make appropriate decisions in the coming years. (
  • The composite film obtained with sodium alginate, sodium carboxymethyl cellulose, and chitosan contents of 1.5%, 0.5%, and 1.5%, respectively, in the casting solution displayed excellent tensile strength, water vapor transmission rate, and elongation after fracture. (
  • Extracted from brown seaweed, sodium alginate is a high viscosity, low solids thickener for all dyes. (
  • sodium alginate LV is a low viscosity, pure sodium alginate suitable for use in pharmaceutical products. (
  • Sodium Alginate is also used in the food industry as an emulsifier to increase viscosity. (
  • In particular, the present invention relates to a dental alginate impression material that is superior in preservability, is free from change of viscosity of the main paste with time and from liquid separation of the setting paste, and does not cause a delay in setting time during the preservation. (
  • The unique combination of calcium alginate and carboxymethylcellulose (CMC) forms a cohesive gel that can absorb up to 18 times its own weight in exudate. (
  • Calcium alginate is a water-insoluble, gelatinous, cream-coloured substance that can be created through the addition of aqueous calcium chloride to aqueous sodium alginate. (
  • Calcium alginate can be produced from a sodium alginate solution by the addition of a calcium salt such as calcium chloride. (
  • Also, check out this "caviar" maker for dripping 96 drops of sodium alginate solutions into calcium chloride at once. (
  • I used sodium alginate from the Texturas series and calcium chloride from a drug store. (
  • In this study, the capability to continuously create mono-disperse droplets in a microfluidic device is used to form calcium-alginate capsules through chemical crosslinking from aqueous droplets of calcium chloride and sodium alginate suspended in an oil solution. (
  • Capsule formation is accomplished through fusion of a sodium alginate droplet and a calcium chloride droplet. (
  • The high surface tension between the droplet of calcium chloride and sodium alginate necessitates the use of the surfactant sodium dodecyl sulfate (SDS) and a device with a judiciously designed geometry. (
  • A composite gel bead was prepared from graphene oxide (GO) and sodium alginate (SA) through a combination of freeze-drying and cross-linking with calcium chloride. (
  • So i just recieved an order from Will Powder of sodium alginate and calcium chloride. (
  • Alginates are used as stabilising, thickening or gelling agents in both food and pharmaceutical products. (
  • The consumption of alginates in the pharmaceutical sector is less in developing countries as compared to developed countries, which presents untapped potential for the market. (
  • What is the scope for sodium alginate market players based on food & pharmaceutical applications? (
  • Sodium alginate is widely used in textile printing, cement compositions, paper coating, pharmaceutical preparations and water-base paints. (
  • SODIUM ALGINATE is used in manufacturing process of pharmaceutical products. (
  • 1.1 This guide covers the evaluation of alginates suitable for use in biomedical or pharmaceutical applications, or both, including, but not limited to, Tissue Engineered Medical Products (TEMPs). (
  • In certain circumstances, P. aeruginosa produces an alginate lyase enzyme which cleaves the polymer into short oligosaccharides. (
  • Here we report the 2.3 Å crystal structure of AlgE, which reveals a monomeric 18-stranded β-barrel characterized by a highly electropositive pore constriction formed by an arginine-rich conduit that likely acts as a selectivity filter for the negatively charged alginate polymer. (
  • The presence of multiple subsites, the electropositive groove, and the non-random distribution of guluronate in the alginate polymer suggest that AlgG is a processive enzyme. (
  • To improve the mechanical resistance of sodium alginate films, the polymer was deposited over the surface of a cellulose acetate support by means of ultrafiltration. (
  • Poly(ethylene oxide) and Its Blends With Sodium Alginate," Polymer 46(24):10750-10757, Nov. 2005. (
  • Electrospinning of Sodium Alginate With Poly(ethylene oxide)," Polymer 47(23):8026-8031, Oct. 2006. (
  • Study of Electrospinning of Sodium Alginate, Blended Solutions of Sodium Alginate/Poly(vinyl alcohol) and Sodium Alginate/Poly(ethylene oxide)," Journal of Applied Polymer Science 104(5):3245-3255, 2007. (
  • The researchers measured the effects of food additives, alpha-amylase, alginate , xanthan, guar gum, carrageenan, carboxymethyl cellulose, distilled monoglyceride and sodium stearoyl lactylate on the hardness of the steamed rice cakes. (
  • The edible film was prepared from blend of three polymers (sodium alginate, sodium carboxymethyl cellulose, and gelatin) based on previous research work. (
  • This solution was then combined with a sodium carboxymethyl cellulose solution and the mixture was cast onto a glass plate and dried at a constant temperature of 60 °C. Then, a carboxymethyl cellulose/sodium alginate/chitosan composite film was obtained by immersing the film in a solution of a cross-linking agent, CaCl 2 , and air-drying the resulting material. (
  • Liu, Y. Preparation and Properties of Sodium Carboxymethyl Cellulose/Sodium Alginate/Chitosan Composite Film. (
  • The aqueous alginate solution is further processed through a clarification procedure. (
  • Since the aqueous alginate solution is very thick at this stage, the solution is diluted with large amount of water then clarified. (
  • Thus, both alginate biosynthetic and degradative enzymes are important for the development, maintenance and spread of P. aeruginosa biofilms. (
  • Alginate contributes to the persistence of P. aeruginosa lung infection by facilitating microcolony formation during biofilm development ( 4 ), protecting the bacteria from opsonic phagocytosis ( 5 ) and limiting the toxicity of oxygen radicals produced by host macrophages ( 6 ). (
  • Alginate is a linear copolymer of 1,4-linked β-D-mannuronic acid (M) and its C-5 epimer α-L-guluronic acid (G). Of the thirteen genes required for the biosynthesis and secretion of alginate by P. aeruginosa , twelve are located on the tightly regulated algD operon. (
  • Failure to eradicate mucoid forms of P. aeruginosa has implicated bacterial alginate in a local evasion of host defence mechanisms within the lung of Cystic Fibrosis (CF) patients. (
  • These data suggest that bacterial alginate by scavenging free radicals, may favour the survival of mucoid forms of P. aeruginosa, particularly in the CF lung. (
  • Encapsulation of explant for synthetic seed production: For encapsulation, nodal segments of size 3 mm were excised from in vitro culture of rose and dipped in sterile solution of sodium alginate (as gel matrix) of various concentrations (1-4%) prepared in full strength MS salts lacking sucrose and phytohormones. (
  • The uses of alginates and modified alginates discussed in this book include tissue regeneration, encapsulation and delivery of drugs, nucleic acid materials, proteins and peptides, genes, herbal therapeutic agents, nutraceuticals, and more. (
  • It concerns a novel application method that is based on encapsulation of EPN and EPB in alginate beads, which are to be improved by supplementing them with useful plant-derived substances. (
  • Calcium-alginate capsules have many potential uses, such as immunoisolation of cells, microencapsulation of active drug ingredients, and encapsulation of bitter agents in food or beverage products. (
  • The method is extended to the encapsulation of cells, molecules and particles of interest within the calcium alginate, and the entire process can be carried out under cell-friendly conditions. (
  • Liposome encapsulation helped to increase the encapsulation efficiency of insulin in alginate-chitosan capsules. (
  • POLYENG aims at developing a set of highly efficient biomolecules, alginates and other uronic acid containing biopolymers, with a wide variety of programmable properties designed for advanced drug delivery systems or as encapsulation matrix for cells. (
  • A common property of the encapsulation systems is that alginates for medical application should have an extreme high degree of purity and lack pathogen-associated molecular patterns (PAMPs) to avoid activation of the recipient's immune system. (
  • Sodium alginate, being a natural polysaccharide, was selected as the polymeric matrix because of its chemical structure and film-forming ability. (
  • Sodium alginate is a type of natural polysaccharide which is extracted from the brown seaweed that grows in cold water regions. (
  • The seaweed extract is filtered to separate the sodium alginate solution from the cellulose contained in the fibrous seaweed residue. (
  • A good affinity between sodium alginate and cellulose acetate was observed. (
  • The algino-cellulose conjugates were formed through citric acid crosslinking of cellulose and alginate. (
  • The modified gauzes contain a citrate conjugate of alginate and cellulose that gels upon hydration. (
  • Fourier transform infrared (FTIR) spectroscopy of the film and alginate-citrate finished cotton showed formation of the alginate and citrate cellulose esters. (
  • Sodium Alginate , also called Algin , is one kind of electrolyte of organic macromolecule among algae of brown algae types, such as kelp, as principal components of cell membrane with other substances. (
  • Alginate is obtained from brown algae comprehends dietary properties. (
  • Propylene glycol alginate ( PGA ) is an emulsifier , stabilizer , and thickener used in food products. (
  • Propylene glycol alginate is stable in acids, and is used to keep the foamy head on beers. (
  • Propylene glycol alginate offers widespread application, hence offers multitude advantages to the manufacturers. (
  • Propylene glycol alginate is extensively used in brewery industry as it stabilises the foam in the beer and hence prevents foam breakdown due to presence of any residual product. (
  • Propylene glycol alginate is comprehensively used in food & beverage industry due to its distinctive properties such as thickening and emulsifying agent. (
  • Therefore, it's wide spread applications accounts to escalating growth of propylene glycol alginate market. (
  • Thus this may hamper the growth of propylene glycol alginate market. (
  • Hence, these factors may inhibit the growth of propylene glycol alginate market. (
  • Thus, propylene glycol alginate market is yet at exploratory stage of development. (
  • Propylene glycol alginate is also used as an ingredient in chewing gums and few condiments. (
  • The global propylene glycol alginate market is categorised into seven regions, namely, Western Europe, Eastern Europe Middle East and Africa (MEA), Asia Pacific excluding Japan (APEJ), , Japan Latin America and, North America. (
  • North America accounts for the highest consumption of propylene glycol alginate. (
  • Europe also comprehends major share of propylene glycol alginate consumption. (
  • Asia pacific region is expected to witness substantial growth for propylene glycol alginate market due to increased awareness on its application across various industries. (
  • To extract the alginate, the seaweed is broken into pieces and stirred with a hot solution of an alkali, usually sodium carbonate. (
  • To understand the molecular basis of alginate epimerization, the structure of Pseudomonas syringae AlgG has been determined at 2.1-Å resolution, and the protein was functionally characterized. (
  • On contact with wound exudate Biatain Alginate Ag converts to a soft, cohesive gel that conforms closely to the wound bed for optimal infection control. (
  • There needs to be a thorough understanding of the synthesis, purification, and characterization of alginates and its derivatives for their utility in healthcare fields, and this volume offers an abundance of information toward that end. (
  • Characterization of Alginate Characterization of sodium alginate was conducted to determine the physical and chemical properties of sodium alginate extraction results. (
  • 4.1 This guide contains a listing of those characterization parameters that are directly related to the functionality of alginate. (
  • This guide can be used as an aid in the selection and characterization of the appropriate alginate for a particular application. (
  • These are: identity of alginate, physical and chemical characterization and testing, impurities profile, and performance-related tests. (
  • 1.2 This guide addresses key parameters relevant for the functionality, characterization, and purity of alginates. (
  • This book also describes the synthesis and characterizations of various alginate and modified alginate systems, such as hydrogels, gels, composites, nanoparticles, scaffolds, etc., used for the biomedical applications and therapeutics. (
  • Update: The Frog Blog has nice posts with pictures showing how Jay Veregge and Joel Robuchon utilize alginate gels. (
  • Cell adhesion studies of mouse myoblasts (C2C12) and human dental stem cells (RP89) to gels containing various amounts of GRGDSP coupled alginate demonstrated the bioactivity of the material where RP89 cells needed higher peptide concentrations to adhere. (
  • 1. A recombinant construct comprising a DNA sequence comprising a coding region for a thermostable alginate lyase enzyme. (
  • The water content is determined based on the dry weight alginate that is a percentage of the dry weight of the initial weight. (
  • The Question: Is magnesium alginate plus simethicone an effective treatment of gastroesophageal reflux (GER) in infants? (
  • He had been using syrups containing the active ingredient including sodium alginate, magnesium alginate and domperidone for four months with a diagnosis of gastroesophageal reflu disease (GER). (
  • The increase in consumption of processed and convenience food products in emerging markets such as Asia-Pacific and Latin American countries have contributed to an increase in the sales of alginates and their derivatives. (
  • In the Asia-Pacific region, annual alginate consumption is expected to increase by 5.9% as the apparel, food and beverage sectors advance rapidly. (
  • Oxygen consumption by neutrophils (unlike that of macrophages) could be detected in a Clark electrode, and was not reduced by alginate, confirming that scavenging of radicals was responsible for the earlier observations. (
  • The major drivers for sodium alginate market include the increasing consumption of convenience foods and their multi-functionality. (
  • Suo and co-workers developed highly stretchable, tough alginate/PAM hybrid DN hydrogels with alginate network ionically crosslinked by various multivalent cations (e.g. (
  • The silk-alginate scaffold promotes adherence of mouse embryonic stem cells and cell survival upon transplantation. (
  • Peptide coupled alginates obtained by chemical functionalization of alginates are commonly used as scaffold materials for cells in regenerative medicine and tissue engineering. (
  • Skjí¥k-Brí¦k, G. "Alginates from Algae" in "Polysaccharides and Polyamides in the Food Industry. (
  • 12. The isolated protein of claim 6 having a thermostable alginate lyase activity on alginate oligo/polysaccharides such that it preferentially cleaves M-G bonds and less preferentially G-G or M-M or G-M bonds. (
  • 15. The isolated protein of claim 6 having a thermostable alginate lyase activity on alginate oligo/polysaccharides such that it preferentially cleaves M-M in an Exo-fashion and yielding preferentially monosugars. (
  • The work show that alginates, which are brown algal cell wall polysaccharides exploited by the industry for their gelifying properties, are accumulated at the surface of areas subject to high tensile stress in the cell wall. (
  • By way of using in production and application, NDY thickener was significantly higher than the cost advantages of alginate and was a completely substitution of sodium alginate. (
  • Sodium alginate is used as a thickener in syrups, sauces, and toppings for ice cream. (
  • Biatain Alginate Ag can be used under compression bandages. (
  • In enzymology, an alginate synthase (EC is an enzyme that catalyzes the chemical reaction GDP-D-mannuronate + (alginate)n ⇌ {\displaystyle \rightleftharpoons } GDP + (alginate)n+1 Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP and (alginate)n+1. (
  • Led by Professor Jeff Pearson of Newcastle University, and backed by the BBSRC, the team identified the chemical properties of alginates which prevent fat from being digested by our bodies, noting that if we can reduce the amount digested, we reduce also the amount absorbed. (
  • Current insight is that although the technology is versatile major research efforts are required for identifying the mechanical, immunological, and physico-chemical requirements that alginate-based capsules should meet for successful human application. (
  • Our objective was to evaluate alginate and alginate-chitosan as encapsulating polymers for glycerol. (
  • Considering the process involving dropping a flavored solution of sodium alginate into a calcium salt solution to form a sphere was patented in 1946 by William Peschardt to manufacture artificial cherries, it would seem we've been eating MG for the holidays for some 60 years… in our fruitcake. (
  • After insertion of the cannula and collection of baseline blood sample a single dose of approximately 20mg of iron as ferrous gluconate incorporated into alginate beads (approximately 22.2g)and added to cola jelly (200ml) will be given to the volunteer together with 3 placebo capsules (each containing 50mg of dextrose)and cola drink (200ml). (
  • The technique of continuous passive separation using co-laminar flow has shown promising results in separating the calcium-alginate capsules from the oil phase and into the aqueous phase. (
  • An oral formulation based on liposome encapsulated alginate-chitosan gel capsules was developed for insulin delivery for the treatment of diabetes. (