Alginates: Salts of alginic acid that are extracted from marine kelp and used to make dental impressions and as absorbent material for surgical dressings.Hexuronic Acids: Term used to designate tetrahydroxy aldehydic acids obtained by oxidation of hexose sugars, i.e. glucuronic acid, galacturonic acid, etc. Historically, the name hexuronic acid was originally given to ascorbic acid.Glucuronic Acid: A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.Polysaccharide-Lyases: A group of carbon-oxygen lyases. These enzymes catalyze the breakage of a carbon-oxygen bond in polysaccharides leading to an unsaturated product and the elimination of an alcohol. EC 4.2.2.Cells, Immobilized: Microbial, plant, or animal cells which are immobilized by attachment to solid structures, usually a column matrix. A common use of immobilized cells is in biotechnology for the bioconversion of a substrate to a particular product. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Pseudomonas aeruginosa: A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.Strontium Isotopes: Stable strontium atoms that have the same atomic number as the element strontium, but differ in the atomic weight. Sr-84, 86, 87, and 88 are the stable strontium isotopes.Dental Impression Materials: Substances used to create an impression, or negative reproduction, of the teeth and dental arches. These materials include dental plasters and cements, metallic oxide pastes, silicone base materials, or elastomeric materials.Laminaria: A genus of BROWN ALGAE in the family Laminariaceae. Dried pencil-like pieces may be inserted in the cervix where they swell as they absorb moisture, serving as osmotic dilators.Carbohydrate Dehydrogenases: Reversibly catalyze the oxidation of a hydroxyl group of carbohydrates to form a keto sugar, aldehyde or lactone. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.; EC 1.1.2.; and 1.1.99.Capsules: Hard or soft soluble containers used for the oral administration of medicine.Microspheres: Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.Uronic Acids: Acids derived from monosaccharides by the oxidation of the terminal (-CH2OH) group farthest removed from the carbonyl group to a (-COOH) group. (From Stedmans, 26th ed)Hydrogels: Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)Sphingomonas: A genus of gram-negative, aerobic, rod-shaped bacteria characterized by an outer membrane that contains glycosphingolipids but lacks lipopolysaccharide. They have the ability to degrade a broad range of substituted aromatic compounds.Chitosan: Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.Gels: Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.Mannose-6-Phosphate Isomerase: An enzyme that catalyzes the reversible isomerization of D-mannose-6-phosphate to form D-fructose-6-phosphate, an important step in glycolysis. EC 5.3.1.8.Silicic Acid: A hydrated form of silicon dioxide. It is commonly used in the manufacture of TOOTHPASTES and as a stationary phase for CHROMATOGRAPHY.Drug Compounding: The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)Dental Disinfectants: Chemicals especially for use on instruments to destroy pathogenic organisms. (Boucher, Clinical Dental Terminology, 4th ed)Azotobacter vinelandii: A species of gram-negative, aerobic bacteria first isolated from soil in Vineland, New Jersey. Ammonium and nitrate are used as nitrogen sources by this bacterium. It is distinguished from other members of its genus by the ability to use rhamnose as a carbon source. (From Bergey's Manual of Determinative Bacteriology, 9th ed)Macrocystis: A genus of BROWN ALGAE in the family Lessoniaceae, and one of the major forms of KELP. The species Macrocystis pyrifera, also known as giant kelp, is the largest of the marine algae.Hydrogel: A network of cross-linked hydrophilic macromolecules used in biomedical applications.Phosphotransferases (Phosphomutases): A group of enzymes that catalyze an intramolecular transfer of a phosphate group. It has been shown in some cases that the enzyme has a functional phosphate group, which can act as the donor. These were previously listed under PHOSPHOTRANSFERASES (EC 2.7.-). (From Enzyme Nomenclature, 1992) EC 5.4.2.Calcium Sulfate: A calcium salt that is used for a variety of purposes including: building materials, as a desiccant, in dentistry as an impression material, cast, or die, and in medicine for immobilizing casts and as a tablet excipient. It exists in various forms and states of hydration. Plaster of Paris is a mixture of powdered and heat-treated gypsum.

Purification and properties of an alginate lyase from a marine bacterium. (1/937)

An unidentified pseudomonad isolated by enrichment procedures from decomposing seaweed was grown in defined medium containing sodium alginate as the sole carbon source. The alginate lyase recovered from disrupted bacterial cells was purified by a procedure of (NH4)2SO4 precipitation, gel filtration and ion-exchange chromatography. From sodium dodecyl sulphate/polyacrylamide-gel-electrophoresis experiments a mol.wt. of about 50 000 was determined. The enzyme was active against both algal and bacterial alginate preparations. Kinetic studies together with analysis of the unsaturated oligouronide products of alginate lyase action indicated the enzyme was specific for guluronic acid-containing regions of the macromolecular substrate. The specificity of the enzyme can be used to give information about the primary composition of alginate samples.  (+info)

Matrix degradation by chondrocytes cultured in alginate: IL-1 beta induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation. (2/937)

OBJECTIVE: To determine the role of interleukin-1 beta (IL-1 beta) in the degradation of proteoglycans and collagen by articular chondrocytes. DESIGN: Chondrocytes were cultured in alginate beads for 2 weeks to produce extracellular matrix, followed by the addition of IL-1 beta for 1 or 2 days. Breakdown of extracellular matrix (with and without activation of pro-matrix metalloproteinases (MMPs) by APMA) was monitored by release of glycosaminoglycans (GAG, proteoglycans) and hydroxyproline (collagen) from the beads into the medium, and by the amount of damaged collagen in the bead. Levels of (pro)MMPs in the beads were assayed by zymography and their activity was quantified fluorometrically. RESULTS: IL-1 beta induced a profound GAG release (approximately 80% after 2 days at 20 ng/ml IL-1 beta) that was both time and IL-1 beta concentration dependent. Under these conditions no increase in collagen release or damaged collagen in the bead was detected. Zymography demonstrated that the synthesis of a variety of proMMPs was induced by IL-1 beta, without a detectable increase of MMP-activity as measured in the activity assay. After activation of the proMMPs by APMA, a time and IL-1 beta concentration-dependent increase in MMP-activity was found, which resulted in almost complete deterioration of collagen already after 18 h of incubation. In the presence of APMA, GAG release from IL-1 beta treated beads was significantly increased from 24 to 31%. CONCLUSIONS: Our data suggest that proteoglycan and collagen degradation are regulated through different mechanisms: IL-1 beta induces the synthesis of active enzymes that degrade proteoglycans, such as 'aggrecanase', and inactive proMMPs. Thus, IL-1 beta alone is not sufficient to result in collagen-degrading MMPs. Once activated, MMPs may account for up to a quarter of the aggrecan degradation in this model.  (+info)

Factors affecting dimensional instability of alginate impressions during immersion in the fixing and disinfectant solutions. (3/937)

To clarify the factors determining the dimensional stability of alginate impressions during immersion in disinfectant and fixing solution, the weight change of impressions in solutions of glutaraldehyde (GA), NaClO, Na2SO4, K2SO4, CaCl2, and ZnSO4 was measured. In the nonelectrolytic solution, GA, the weight decreased in proportion to concentration, possibly due to the gradient of osmotic pressure between the impression and solution. In monovalent metallic salt solutions the weight change decreased with increased concentration. Especially at lower concentrations the rate of weight loss was high. A chemical action of the solution might also be involved, in addition to the osmotic pressure difference. The weight loss in divalent metallic salt solutions was greater than in monovalent solutions, implicating crosslinking reactions between the impression and solution.  (+info)

Study of the response of a biofilm bacterial community to UV radiation. (4/937)

We have developed a bioluminescent whole-cell biosensor that can be incorporated into biofilm ecosystems. RM4440 is a Pseudomonas aeruginosa FRD1 derivative that carries a plasmid-based recA-luxCDABE fusion. We immobilized RM4440 in an alginate matrix to simulate a biofilm, and we studied its response to UV radiation damage. The biofilm showed a protective property by physical shielding against UV C, UV B, and UV A. Absorption of UV light by the alginate matrix translated into a higher survival rate than observed with planktonic cells at similar input fluences. UV A was shown to be effectively blocked by the biofilm matrix and to have no detectable effects on cells contained in the biofilm. However, in the presence of photosensitizers (i.e., psoralen), UV A was effective in inducing light production and cell death. RM4440 has proved to be a useful tool to study microbial communities in a noninvasive manner.  (+info)

The A modules of the Azotobacter vinelandii mannuronan-C-5-epimerase AlgE1 are sufficient for both epimerization and binding of Ca2+. (5/937)

The industrially important polysaccharide alginate is composed of the two sugar monomers beta-D-mannuronic acid (M) and its epimer alpha-L-guluronic acid (G). In the bacterium Azotobacter vinelandii, the G residues originate from a polymer-level reaction catalyzed by one periplasmic and at least five secreted mannuronan C-5-epimerases. The secreted enzymes are composed of repeats of two protein modules designated A (385 amino acids) and R (153 amino acids). The modular structure of one of the epimerases, AlgE1, is A1R1R2R3A2R4. This enzyme has two catalytic sites for epimerization, each site introducing a different G distribution pattern, and in this article we report the DNA-level construction of a variety of truncated forms of the enzyme. Analyses of the properties of the corresponding proteins showed that an A module alone is sufficient for epimerization and that A1 catalyzed the formation of contiguous stretches of G residues in the polymer, while A2 introduces single G residues. These differences are predicted to strongly affect the physical and immunological properties of the reaction product. The epimerization reaction is Ca2+ dependent, and direct binding studies showed that both the A and R modules bind this cation. The R modules appeared to reduce the Ca2+ concentration needed for full activity and also stimulated the reaction rate when positioned both N and C terminally.  (+info)

Regulation of alginate biosynthesis in Pseudomonas syringae pv. syringae. (6/937)

Both Pseudomonas aeruginosa and the phytopathogen P. syringae produce the exopolysaccharide alginate. However, the environmental signals that trigger alginate gene expression in P. syringae are different from those in P. aeruginosa with copper being a major signal in P. syringae. In P. aeruginosa, the alternate sigma factor encoded by algT (sigma22) and the response regulator AlgR1 are required for transcription of algD, a gene which encodes a key enzyme in the alginate biosynthetic pathway. In the present study, we cloned and characterized the gene encoding AlgR1 from P. syringae. The deduced amino acid sequence of AlgR1 from P. syringae showed 86% identity to its P. aeruginosa counterpart. Sequence analysis of the region flanking algR1 in P. syringae revealed the presence of argH, algZ, and hemC in an arrangement virtually identical to that reported in P. aeruginosa. An algR1 mutant, P. syringae FF5.32, was defective in alginate production but could be complemented when algR1 was expressed in trans. The algD promoter region in P. syringae (PsalgD) was also characterized and shown to diverge significantly from the algD promoter in P. aeruginosa. Unlike P. aeruginosa, algR1 was not required for the transcription of algD in P. syringae, and PsalgD lacked the consensus sequence recognized by AlgR1. However, both the algD and algR1 upstream regions in P. syringae contained the consensus sequence recognized by sigma22, suggesting that algT is required for transcription of both genes.  (+info)

Biodegradable alginate microspheres as a delivery system for naked DNA. (7/937)

Sodium alginate is a naturally occurring polysaccharide that can easily be polymerized into a solid matrix to form microspheres. These biodegradable microspheres were used to encapsulate plasmid DNA containing the bacterial beta-galactosidase (LacZ) gene under the control of either the cytomegalovirus (CMV) immediate-early promoter or the Rous sarcoma virus (RSV) early promoter. Mice inoculated orally with microspheres containing plasmid DNA expressed LacZ in the intestine, spleen and liver. Inoculation of mice with microspheres containing both the plasmid DNA and bovine adenovirus type 3 (BAd3) resulted in a significant increase in LacZ expression compared to those inoculated with microspheres containing only the plasmid DNA. Our results suggest that adenoviruses are capable of augumenting transgene expression by plasmid DNA both in vitro and in vivo.  (+info)

R-factor inheritance and plasmid content in mucoid Pseudomonas aeruginosa. (8/937)

Eighteen strains of alginate-producing mucoid Pseudomonas aeruginosa were evaluated with respect to plasmid content and the ability to maintain well-characterized R plasmids. The spontaneous loss of alginate production in these strains varied from 0.01 to 0.7% and was not significantly increased by plasmid curing regimens. Examination of cleared lysates of these strains and their isogenic nonmucoid derivatives by agarose gel electrophoresis failed to reveal plasmid DNA. R-plasmid (P-incompatibility-group) transfer to mucoid P. aeruginosa was unaffected by the presence of the alginate capsule. Maintenance and expression of such plasmids in the mucoid strains were confirmed by agarose gel electrophoresis and by verification of plasmid-linked drug resistance and pilus-specific bacteriophage sensitivity. These studies demonstrate that alginate production does not appear to be plasmid linked and that mucoid P. aeruginosa are capable of receiving and donating certain drug resistance plasmids. Since some of the plasmids used here have been shown to mobilize chromosomal DNA, strains constructed in this study should afford the means for exploring the genetic basis of the mucoid phenotype.  (+info)

*Calcium alginate

To the sodium alginate from the initial extraction solution, a calcium salt is added. This causes calcium alginate to form with ... Calcium alginate is also used for entrapment of enzymes and forming artificial seeds in plant tissue culture. "Alginate" is ... Over a period of about two hours, the alginate dissolves as sodium alginate to give a very thick slurry. This slurry also ... The rationale behind the extraction of alginate from the seaweed is to convert all the alginate salts to the sodium salt, ...

*Alginic acid

Alginate seaweed sources Alginate properties Alginate medical uses article Wired on Easy Cheese, describing sodium alginate. ... Sodium alginate is a gum, extracted from the cell walls of brown algae. Potassium alginate is a chemical compound that is the ... Calcium alginate, made from sodium alginate from which the sodium ion has been removed and replaced with calcium, has the ... Dental impression material utilizes alginate as its means of gelling. Alginate is both food and skin safe. Seaweeds can be ...

*Alginate dressing

Alginate is initially extracted from the cell wall of Brown seaweeds. Alginate dressings can be in the form of freeze-dried, ... Alginate dressings are useful for moderate to heavily exuding wounds. In the form of fibres trapped in a wound, alginate is ... A comparative study of hydrocolloid dressings and alginates showed that alginates gels remain on the wound for a longer period ... The ease of biodegradation is exploited in making alginate sutures used in surgical wound closures. Since alginate dressings ...

*Alginate synthase

... alginate)n+1 Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP ... In enzymology, an alginate synthase (EC 2.4.1.33) is an enzyme that catalyzes the chemical reaction GDP-D-mannuronate + ( ... The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. This enzyme is also called ... and (alginate)n+1. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. ...

*Propylene glycol alginate

Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are ... Propylene glycol alginate (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E ... List of food additives, Codex Alimentarius Propylene glycol alginate, Food and Agriculture Organization of the United Nations ... What is the "propylene glycol alginate" found in salad dressings? at The Straight Dope. ...

*Saccharina japonica

The harvest is also used for the production of alginates, with China producing up to ten thousand tons of the product each year ... "Alginates". www.seaweed.ie. Miyai, Kiyoshi; Tokushige, Tomoyasu; Kondo, Masahiko (2008-12-01). "Suppression of thyroid function ...

*Streptomyces psammoticus

ISBN 1-4398-4887-4. CS1 maint: Extra text: authors list (link) editor, Bernd H. A. Rehm, (2009). Alginates biology and ...

*Index of oral health and dental articles

Sodium alginate • Soft palate • SoftDent • SOHP • Sonicare • Southern Regional Testing Agency • Sozodont • Speech organ • ... Potassium alginate • Premolar • Preparation • Primordial cyst • Procaine • Procter & Gamble • Prognathism • Prosthodontics • ...

*Laminaria hyperborea

Alginates can be extracted from L. hyperborea. In France, Ireland, Scotland and Norway, stipes cast up on beaches are collected ...

*Food microbiology

Alginates can be used as thickening agents. Although listed here under the category 'Microbial polysaccharides', commercial ... ISBN 978-1-904455-36-3. Remminghorst & Rehm (2009). "Microbial Production of Alginate: Biosynthesis and Applications". ... alginates are currently only produced by extraction from brown seaweeds such as Laminaria hyperborea or L. japonica. Poly-γ- ...

*Organ printing

Hydrogel alginates have emerged as one of the most commonly used materials in organ printing research, as they are highly ... Materials for 3D printing usually consist of alginate or fibrin polymers that have been integrated with cellular adhesion ... Augst, Alexander D.; Kong, Hyun Joon; Mooney, David J. (2006). "Alginate Hydrogels as Biomaterials". Macromolecular Bioscience ...

*Photolabile protecting group

"Small-Angle X-Ray Scattering and Rheological Characterization of Alginate Gels. 1. Ca−Alginate Gels". Macromolecules. 33 (5): ...

*Edible water bottle

Sodium alginate is an unbranched copolymer of 1,4-linked-β-d-mannuronate (M) and α-l-guluronate (G) sugars. Sodium alginate ( ... Alginates are the natural product of brown algae and have been used extensively in wound dressing, drug delivery and tissue ... "CALCIUM ALGINATE - National Library of Medicine HSDB Database". toxnet.nlm.nih.gov. Archived from the original on 2017-11-15. ... The edible water bottle is a blob-like water container made from sodium alginate gel. The biodegradable blob was created by ...

*Bio-ink

Additionally, these alginate-based bioinks can be blended with other materials such as nanocellulose for application in tissues ... Alginates are particularly suitable for bioprinting due to their mild cross-linking conditions via incorporation of divalent ... Jia, Jia (2014). "Engineering alginate as bioink for bioprinting". Acta Biomaterialia. 10 (10): 4323-4331. Markstedt, Kajsa ( ... Alginate is a naturally derived biopolymer from the cell wall of brown algae that has been widely used as a biomaterial. ...

*Reverse spherification

The amount of free calcium ion needs to be sufficient in order to form a gel-like capsule reaction with Sodium Alginate. Milk ... When the liquid containing alcohol or calcium salt got dropped into an alginate bath, the liquid will draw itself into a ... Both the liquid for consumption and the alginate bath should be left to stand after preparing to eliminate air bubbles. Air ... After removing the jelly from the alginate bath, calcium would not continue to diffuse into the center of the sphere, therefore ...

*Durvillaea

Cheshire, Anthony C.; Hallam, Neil D. (1985). "The environmental role of alginates in Durvillaea potatorum (Fucales, Phaeophyta ...

*Postelsia

Their cell walls are composed of alginate. They use laminarin and mannitol for storage. Like most brown algae, Postelsia goes ...

*Poly(beta-D-mannuronate) lyase

Other names in common use include alginate lyase I, alginate lyase, alginase I, alginase II, and alginase. This enzyme ... Davidson IW, Lawson CJ, Sutherland IW (1977). "An alginate lysate from Azotobacter vinelandii phage". J. Gen. Microbiol. 98 (1 ...

*Diabetic foot ulcer

Dumville, JC; O'Meara, S; Deshpande, S; Speak, K (25 June 2013). "Alginate dressings for healing diabetic foot ulcers". The ... Dressings and creams containing silver have not been properly studied nor have alginate dressings. Biologically active bandages ...

*Natural gum

... and Sodium alginate (E401); Carrageenan (E407); Natural gums obtained from non-marine botanical resources: Polyelectrolytes: ...

*GE Betz

Collogel dispersed sodium alginate in domestic water systems. Two years later the company introduced Adjunct for use in ...

*Dysgonomonas alginatilytica

nov., an alginate-degrading bacterium isolated from a microbial consortium". International Journal of Systematic and ... Dysgonomonas alginatilytica has the ability to degrade alginate. Parte, A.C. "Dysgonomonas". www.bacterio.net. "Dysgonomonas ...

*Seaweed fertiliser

In terms of soil structure, seaweed does not add a great deal of bulk, but its jelly like alginate content helps to bind soil ... Rinsing seaweed is risky as valuable alginates are potentially lost to runoff. Organic fertilizer Organic gardening Organic ...

*Sargassum muticum

Water treatment: the cell walls of S. muticum contains alginates and fucoidans. The association of both molecules forms a ...

*Philippine Nuclear Research Institute

It is made from local honey and Sodium Alginate. The PNRI utilizes nuclear techniques in addressing problems in air pollution, ... De Guzman, "Radiation-Sterilized Honey Alginate Wound Dressing for Exudating Wounds and Burns." n.d. Castañeda and Sombrito, ... De Guzman, Zenaida M. "Radiation-Sterilized Honey Alginate Wound Dressing for Exudating Wounds and Burns." PNRI. Retrieved July ... Through the process of Radiation Processing, Radiation-Sterilized Honey Alginate Wound Dressing was also developed; which is ...
Calcium alginate is a water-insoluble, gelatinous, cream-coloured substance that can be created through the addition of aqueous calcium chloride to aqueous sodium alginate. Calcium alginate is also used for entrapment of enzymes and forming artificial seeds in plant tissue culture. "Alginate" is usually the salts of alginic acid, but it can also refer to derivatives of alginic acid and alginic acid itself; in some publications the term "algin" is used instead of alginate. Alginate is present in the cell walls of brown algae, as the calcium, magnesium and sodium salts of alginic acid. To extract the alginate, the seaweed is broken into pieces and stirred with a hot solution of an alkali, usually sodium carbonate. Over a period of about two hours, the alginate dissolves as sodium alginate to give a very thick slurry. This slurry also contains the part of the seaweed that does not dissolve, mainly cellulose. This insoluble residue must be removed from the solution. The solution is too thick ...
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This study developed a drug-loadable hydrogel system with high plasticity and favorable biological properties to enhance oral bone tissue regeneration. Hydrogels of different calcium alginate concentrations were prepared. Their swelling ratio, degradation time, and bovine serum albumin (BSA) release rate were measured. Human periodontal ligament cells (hPDLCs) and bone marrow stromal cells (BMSCs) were cultured with both calcium alginate hydrogels and polylactic acid (PLA), and then we examined the proliferation of cells. Inflammatory-related factor gene expressions of hPDLCs and osteogenesis-related gene expressions of BMSCs were observed. Materials were implanted into the subcutaneous tissue of rabbits to determine the biosecurity properties of the materials. The materials were also implanted in mandibular bone defects and then scanned using micro-CT. The calcium alginate hydrogels caused less inflammation than the PLA. The number of mineralized nodules and the expression of osteoblast-related genes
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Alginate hydrogels are commonly used in biomedical applications such as scaffolds for tissue engineering, drug delivery, and as a medium for cell immobilization. Multivalent cations are often employed to create physical crosslinks between carboxyl and hydroxyl moieties on neighbouring polysaccharide chains, creating hydrogels with a range of mechanical properties. This work describes the manufacture and characterisation of sodium alginate hydrogels using the divalent cations Mg2+, Ca2+ and Sr2+ to promote gelation via non-covalent crosslinks. The gelation time and Youngs modulus are characterised as a function of cation and alginate concentrations. The implications of this work towards the use of environmental elasticity to control stem cell differentiation are discussed.. ...
Sodium and potassium alginate are intended to be used as technological additives (functional groups: emulsifiers, stabilisers, thickeners, gelling agents and binders). Sodium alginate is intended to be used in feedingstuffs for pets, other non food-producing animals and fish, with no maximum recommended use level. Potassium alginate is intended to be used in feedingstuffs for cats and dogs at levels up to 40,000 mg/kg feed (on dry matter). Since the functional properties of the additives are determined by the alginate content, sodium and potassium alginate were considered equivalent. The maximum dose considered safe for cats, dogs, other non food-producing animals, salmonids and other fish is 40,000 mg alginates (sodium and potassium salts)/kg complete feed. The use of alginates in feedingstuffs for fish is of no concern for the consumer. Alginates are reported not to be irritant to the skin but mildly irritant to the eyes. They are considered as potential sensitisers to the skin and the ...
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Oxygen-dependent alginate synthesis and enzymes in Pseudomonas aeruginosa.: Alginate production by the highly alginate-producing Pseudomonas aeruginosa 8821M wa
Alginates have many beneficial uses across a wide variety of industries. Alginates are salts of alginic acid taking the form of sodium, calcium and/or ammonium alginate precipitated from brown seaweed (algae).
The extracellular biofilm matrix includes primarily DNA and exopolysaccharides (EPS), which function to maintain aggregate structures and to protect biofilms from antibiotics and the immune response. Both polymers are anionic and have cation binding activity, however the impact of this activity on biofilms is not fully understood. Host cell contact is considered the primary signal for activation of most type III secretion systems (T3SS), although calcium limitation is frequently used as a trigger of contact-independent T3SS expression. We hypothesized that alginate, which is a known calcium binding exopolysaccharide produced in mucoid Pseudomonas aeruginosa isolates, can activate the T3SS in biofilms. The addition of exogenous purified alginate to planktonic, non-mucoid PAO1 cultures induced expression of exoS, exoT and exoY-lux reporters of the T3SS in a concentration-dependent manner. Induction by alginate was comparable to induction by the calcium chelator NTA. We extended our analysis of the T3SS in
Research work that began in 2013 has been able to establish, optimise and standardise the cultivation of the soil bacterium and the biotechnological process for producing and isolating bacterial alginates. By working specifically on optimising the bacteriums alginate biosynthesis, the researchers succeeded in improving the composition, and therefore the properties and yield of the alginate. This meant that they could make customised alginates that are particularly suitable for producing fibres for use in medical products. In a pilot production facility, the research partners were able to spin fibres from alginate and alginate-viscose, and turn them into innovative nonwoven materials and wound dressings within the established process. When the new wound dressings were tested in use, the alginate product that had been made using biotechnology was impressive for its liquid absorption capacity, which was significantly better than that of commercially available marine alginate-based wound dressings. ...
The high cost of soluble enzymes can limit their use for commercial and industrial purposes. Immobilization can enhance enzyme reusability, thereby reducing product isolation costs and overcoming this economic barrier. In the current study, two novel, purified lipases from Pseudomonas sp. (Pseudomonas reinekei and Pseudomonas brenneri) were entrapped in a calcium alginate matrix, with the aim of simultaneously enhancing enzyme reusability and stability. Following entrapment, the retained activity of the enzyme-alginate composite was verified by an enzymatic hydrolysis reaction of a p-nitrophenol palmitate substrate. The effect of the enzyme-alginate entrapment against various physiochemical parameters such as pH, temperature, metal ions, and solvents were subsequently examined. The entrapment was found to have minimal beneficial stability gains. However, enhanced enzyme reusability (up to 3 cycles) and stability (up to 18 days at 4°C) of the calcium alginate entrapped lipase, as indicated by
Objectives. This study determined the effect of alginate adhesive on various bond strengths of alginate to stainless steel. Methods. Three test assemblies were designed and machined in stainless steel for tension, shear and cleavage tests. Alginate adhesive (Fix™) was applied thinly and dried for 5 min. Alginate (Blueprint™) was then loaded and allowed to set for 5 min before testing. The force at failure was measured by an Instron machine with a cross-head speed of 50 mm min-1. Results. Breaking stresses of alginate without adhesive were found to be 65 kPa (tension), 31 kPa (shear) and 10 kPa (cleavage). The bond strengths of Blueprint with Fix were 100 kPa (tension), 42 kPa (shear) and 37 kPa (cleavage) giving improvements of 53%, 37% and 270% respectively (p < 0.05). Conclusions. Alginate adhesive increases the bond strength of alginate, particularly cleavage, to stainless steel. © 1998 Elsevier Science Ltd. All rights reserved ...
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This review provides a critical update on human and animal studies investigating the effect of alginate supplementation on appetite regulation, glycaemic and insulinemic responses, and lipid metabolism with discussion of the evidence on potential mechanisms, efficacy and tolerability. Dependent on vehicle applied for alginate supplementation, the majority of animal and human studies suggest that alginate consumption does suppress satiety and to some extent energy intake. Only one long-term intervention trial found effects on weight loss. In addition, alginates seem to exhibit beneficial influence on postprandial glucose absorption and insulin response in animals and humans. However, alginate supplementation was only found to have cholesterol-lowering properties in animals. Several mechanisms have been suggested for the positive effect observed, which involve delayed gastric emptying, increased viscosity of digesta and slowed nutrient absorption in the small intestine upon alginate gel formation. ...
Here, we sought to develop a cell culture surface conversion technique that would not damage living cells. An alginate thin film, formed on a glass plate by spin coating of sodium alginate solution and dipping into calcium chloride solution, was used to inhibit adhesion of cells. The film could be removed by ethylenediaminetetraacetate (EDTA) at any time during cell culture, permitting observation of cellular responses to conversion of the culture surface in real time. Additionally, we demonstrated the validity of the alginate thin film coating method and the performance of the film. The thickness of the alginate thin film was controlled by varying the rotation speed during spin coating. Moreover, the alginate thin film completely inhibited the adhesion of cultured cells to the culture surface, irrespective of the thickness of the film. When the alginate thin film was removed from the culture surface by EDTA, the cultured cells adhered to the culture surface, and their morphology changed. ...
The two-phase model used previously to calculate the polymer-subphase volume of alginic acid was applied to interpret the dependence of apparent metal binding equilibrium on environmental conditions. In this model, the polymer subphase, a small aqueous region surrounding the polymer chain, was considered as a separate phase in the aqueous solution and as a protonation-deprotonation and metal binding reaction zone. Three factors were taken into account when treating experimental data: (1) the electric field due to the charged ligands on the polymer molecule, (2) the effective concentration of ligands based on polymer-subphase volume, and (3) the competition from hydrogen ions for the metal binding sites. The data of base titration of alginic acid in the presence of trace amounts of copper at different alginic acid concentrations and ionic strengths yielded unique intrinsic stability constants for complexes formed between a cupric ion and one or two binding ligands ...
Calcium alginate is a substance formed from seaweed and used in specialized wound dressings. The purpose of calcium alginate is to combine with wound...
Alginate overproduction, or mucoidy, plays an important role in the pathogenesis of P. aeruginosa lung infection in cystic fibrosis (CF). Mucoid strains with mucA mutations predominantly populate in chronically-infected patients. However, the mucoid strains can revert to nonmucoidy in vitro through suppressor mutations. We screened a mariner transposon library using CF149, a non-mucoid clinical isolate with a misssense mutation in algU(AlgUA61V). The wild type AlgU is a stress-related sigma factor that activates transcription of alginate biosynthesis. Three mucoid mutants were identified with transposon insertions that caused 1) an overexpression of AlgUA61V, 2) an overexpression of the stringent starvation protein A (SspA), and 3) a reduced expression of the major sigma factor RpoD (σ70). Induction of AlgUA61V in trans caused conversion to mucoidy in CF149 and PAO1DalgU, suggesting that AlgUA61V is functional in activating alginate production. Furthermore, the level of AlgUA61V was increased in all
Alginic acid, also called algin or alginate, is an anionic polysaccharide distributed widely in the cell walls of brown algae, where through binding with water it forms a viscous gum. It is also a significant component of the biofilms produced by the bacterium Pseudomonas aeruginosa, the major pathogen in cystic fibrosis, that confer it a high resistance to antibiotics and killing by macrophages. Its colour ranges from white to yellowish-brown. It is sold in filamentous, granular or powdered forms. Alginic acid is a linear copolymer with homopolymeric blocks of (1-4)-linked β-D-mannuronate (M) and its C-5 epimer α-L-guluronate (G) residues, respectively, covalently linked together in different sequences or blocks. The monomers can appear in homopolymeric blocks of consecutive G-residues (G-blocks), consecutive M-residues (M-blocks) or alternating M and G-residues (MG-blocks). Alginates are refined from brown seaweeds. A wide variety of brown seaweeds of the phylum Phaeophyceae are harvested ...
Alginate can be produced by a microbial fermentation using bacteria such as Azobacter Vinelandii and Pseudomonas Aeruginosa (Linker and Jones 1964, Gorin and Spencer 1966). These bacteria produce a polysaccharide with a structure resembling alginate, differing only in that there are acetyl groups on a portion of the C2 and C3 hydroxyls. It is believed that the acetate groups are associated mainly with the D-mannuronic acid residues (Davidson 1977, Sutherland 1983, Paul 1986). The level of acetylation is variable as is the mannuronic and guluronic acid content. However the level of guluronic acid in the final polymer can be controlled to some extent by altering the level of calcium in the fermentation broth (Haug and Larsen 1971). The sequence structures and acetylation patterns of bacterial alginate, from different sources, have been studied with 2D COSY proton NMR techniques. The acetyl residues were found to be exclusively associated with the mannuronic acid residues with degrees of ...
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Alginate lyase (Sphingomonas sp.) [ME-ALGLS] - High purity recombinant Alginate lyase (Sphingomonas sp.) for use in research, biochemical enzyme assays and in vitrodiagnostic analysis. EC 4.2.2.3 CAZY Family: PL7 Recombinant. From Sphingomonas sp. In 3.2 M ammonium sulphate. endo-acting β-elimination cleavage of the polysaccharide, alginate. Specific activity: ~ 120 U/mg (40oC, pH 7.2 on sodium alginate). Store at 4oC.
In accordance with this invention, an aqueous solution of drug or drugs and alginate is prepared in DW/NS/PBS with an alginate: drug ratio of 1:6-1:8 w/w and a final alginate concentration of 0.05-0.07% w/v. Methanol may be added (if one of the drug is hydrophobic) in a ratio of 0.2:1-10 v/v. The mixture can comprise an excess amount of drug solution or sodium alginate solution, but which would only constitute a waste. To the mixture is added an aqueous solution of calcium chloride (drug-alginate solution: calcium chloride solution-18:1-22:1 v/v) with a molarity of calcium chloride maintained between 15-20mM. To the mixture is further added an aqueous solution of chitosan (drug-alginate solution: chitosan solution=8:1-12:1 v/v) with an alginatexhitosan ratio maintained preferably, but not limited to a ratio between 4:1-7:1 w/w. The nanoparticles formed are left as such for l-18h and subsequently collected by centrifugation at 19,000-37,000 rpm, at 4°C-30°C for 30 min-45 min ...
Packaging & Delivery Packaging Details:25kg bags E401 Sodium Alginate Delivery Detail:Prompt Specifications Sodium Alginate Powder Food Grade white or yellowish granular or powder CAS No. 9005-38-3 25kgs/bag shlef life:2 years E401 Sodium Alginate...
Alginate is used in various pharmaceutical preparations. Chemically, it is a linear copolymer with homopolymeric blocks of (1-4)-linked ?-D-mannuronate (M) and its C-5 epimer ?-L-guluronate (G) residues, respectively, covalently linked together in different sequences or blocks. Alginic acid can be separated from benzoate, citric acid and saccharin by mixed-mode chromatography on Primesep C HPLC column. This method can be used to quantitate alginic acid, citric acid or saccharin in complex mixtures. Various detection technique can be used (UV, ELSD, LC/MS), based on mobile phase selection. ...
Chitosan, carrageenan and alginate are among the most abundant biopolymers in nature. They were prepared in uniform beads shape with a diameter of 2 mm ± 10%, using the encapsulator for removal of calcium, magnesium and iron cations from hard water. Solutions of 100-500 mg/L were prepared from each cation, and the detection of cations was carried out using atomic absorption spectrometer. Carrageenan and chitosan were able to chelate the three cations without further modification. However, alginate beads succeeded to chelate iron and magnesium and failed to chelate any calcium ions; in contrast, it increased the initial calcium concentration! That could be due to the pre-cross-linking of alginate beads using calcium chloride solution, which may be leaked back to the solution. However, grafting the alginate beads with polyethyleneimine and bromoacetic acid rectified this problem and the new functional group, -COOH, has been proved using the FT-IR. Optimization of the results in terms of beads ...
Injection of a biomaterial scaffold into the infarcted myocardium can replace the injured extracellular matrix and improve the mechanical strength of the scar. The present study aimed to determine and compare the effect of novel injectable alginate scaffold, with or without staged cardiomyocyte transplantation, with injectable collagen scaffold, or saline on left ventricular (LV) remodeling and function after myocardial infarction (MI) in rat. We developed a novel injectable, absorbable biomaterial composed of a calcium cross-linked alginate solution, which displays low viscosity and undergoes phase transition into hydrogel after injection into the infarct. Rats (n=58) were subjected to anterior MI and subsequently treated with injection of alginate biomaterial (n=22), collagen (n=12), or saline (n=12) into the infarct. One week later, 10 of 22 biomaterial-treated rats and 10 MI rats received rat fetal cardiomyocyte transplantation (1×10 6 cells) into the scar. Hemodynamic studies, performed ...
Feb 24, 2016 ... Propylene glycol alginate (PGA) is an emulsifier, stabilizer, and thickener used as a food additive with E number 405. Chemically speaking, propylene glycol alginate is an ester of alginic acid, which is ... Sodium Alginate.. Read More ...
Algal alginates are of great importance for industrial applications. Since their properties depend on the kind of algae and the time of harvesting, supply problems caused price fluctuations. Hence, current research focuses on alternative alginate sources. Back in the 60s, exopolysaccharides similar to algal alginates were found. They were produced by mucoid Pseudomonas aeruginosa strains which embed themselves in a slime matrix containing bacterial alginates. The focus of this thesis was a comparisons of the physico-chemical properties of bacterial and algal alginates. The main results of the performed investigations are as follows: a) both substances aggregate in highly diluted solutions, b) bacterial alginates have a bigger molar mass than algal alginates, c) their mean squared radii of gyration are bigger than those of algal alginates, d) the second osmotic virial coefficients of these systems are negative and temperature dependent, e) acetylation of alginates support the aggregation, f) ...
This study is a randomised, single blinded, cross-over trial with participants randomly allocated into two groups: A (n= 8 volunteers) and B (n=8 volunteers). The study will include a total of four arms.. By administration of test meals #1 (iron in alginate beads) and #4 (iron in a capsule) the possible protective effect of alginate on iron absorption will be investigated. By administration of test meal #2 (iron in alginate beads + calcium capsule)and #3 (iron in a capsule + calcium in a capsule)the study will investigate whether alginates can bind calcium (a well-known iron inhibitor) in vivo, thus diminish the potential negative effect of calcium on iron absorption.. Only half (8) of the volunteers will undergo treatments including calcium. Therefore group A will undergo all 4 tests, whereas group B will undergo 2 out of 4 tests.. The four test meals will be administered a week apart following an overnight fast. On each occasion blood sampling will take place over a period of 6h with samples ...
SILVERCEL Antimicrobial Alginate Dressing . SILVERCEL Antimicrobial Alginate Dressing is an effective barrier to bacterial penetration. SILVERCEL Antimicrobial Alginate Dressing is also great for pressure ulcers, venous ulcers, diabetic ulcers and surgical wounds.
Lists the various brand names available for medicines containing alginic acid. Find information on alginic acid use, treatment, drug class and molecular formula.
Sodium Alginate (SA) Alginates are extracted from brown seaweeds which are usually found in cold waters. Alginates are very versatile and can form ge...
Figure from Draget, K. I.; Smidsrød, O.; Skjí¥k-Brí¦k, G. "Alginates from Algae" in "Polysaccharides and Polyamides in the Food Industry. Properties, Production, and Patents", Steinbí¼chel and Rhee (Ed.), Wiley 2005.. When alginate is coordinated to sodium, its a very flexible chain. When sodium is replaced by calcium however, each calcium ion (black dots in the image below) coordinates to two alginate chains, linking them together. The flexible chains become less flexible and form a huge network - a gel. The fun thing is that this happens within seconds after the alginate mixture is dripped into the water bath with the calcium ions.. ...
... _sodium alginate food grade is widely used as thickeners visitchem product sodiumalginateSodium alginate can be used as stabilizer to replace starch and gelatin in ice cream, at the same time,
Restore Calci Care Calcium Alginate Dressings are significantly more absorbent so you need to change them less often. That means less trauma for the...
RX Vitamins Alginate Detox SupplementAlginate Plus provides optimum levels of high-binding alginate and standardized milk thistle in vegetarian capsules. Studies have demonstrated that alginates bind tightly to certain heavy metals and is thus beneficial for those individuals exposed to environmental pollutants or toxins.Supplement Facts Bottle Contains 120 Vegetarian Capsules One Capsule provide:Calories 0Calories from Fat 0Total Fat 0gAlginate (sodium alginate) 400mgMilk Thistle (standardized 80% silymarin) 40mgOther Ingredients: Silicon Dioxide, Kosher Rice Flour, VegiCap (hypromellose)Recommended Usage: As a dietary supplement, take one capsule three times daily with a full glass of water, or as directed by your health care professional.
Conversion to a mucoid, exopolysaccharide alginate-overproducing phenotype in Pseudomonas aeruginosa is associated with chronic respiratory infections in cystic fibrosis. Mucoidy is caused by muc mutations that derepress the alternative sigma factor AlgU, which in turn activates alginate biosynthetic and ancillary regulatory genes. Here we report the molecular characterization of two newly identified genes, algW and mucD, that affect expression of mucoidy. The algW gene, mapping at 69 min, was isolated on the basis of its ability to suppress mucoidy and reduce transcription of the alginate biosynthetic gene algD. The predicted primary structure of AlgW displayed similarity to HtrA (DegP), a serine protease involved in proteolysis of abnormal proteins and required for resistance to oxidative and heat stress in enteric bacteria. Inactivation of algW on the chromosome of the wild-type nonmucoid strain PAO1 caused increased sensitivity to heat, H2O2, and paraquat, a redox cycling compound inducing ...
In this work an enzyme encapsulation general approach, based on the use of calcium alginate hydrogels, is reported. Alginate gels are biodegradable and low cost and have been found to provide a good matrix for the entrapment of sensitive biomolecules. Alginate is an anionic polymer whose gelation occurs by an exchange of sodium ions from the polymer chains with multivalent cations, resulting in the formation of a three dimensional gel network. For gelation alginate is dripped into a calcium chloride solution. The cations diffuse from the continuous phase to the interior of the alginate droplets and form a gelled matrix. By means of this
[150 Pages Report]Alginates & Derivatives Market categorizes the global market by Type (Sodium Alginate, Calcium Alginate, Others), Application (Food & Beverage, Industrial, Others), & by Region
Wound care items that are composed of calcium alginate. Calcium alginate is a component of seaweed. When in contact with a wound the calcium in the dressing is exchanged with sodium from the wound fluid. This turns the dressing into a gel
Looking for alginate? Find out information about alginate. An algal polysaccharide that is a major constituent of the cell walls of brown algae Explanation of alginate
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2-Surface Protective Agents. Surface protective agents usually contain alginate or sucralfate. Alginates are insoluble salts of alginic acid, a common anionic polysaccharide found in the cell walls of some algae. Alginate acts as a gumming agent and is typically combined with sodium bi-carbonate/potassium bicarbonate. When exposed to gastric acid, the bicarbonate is converted to carbon dioxide, which is then trapped by the alginate gel, forming a foam raft that floats atop the gastric contents. In doing so, it acts as a buffering agent as well as a physical barrier to reflux of gastric contents into the esoph-agus. A systematic review of studies of alginates in children revealed variable efficacy with evidence that these preparations can marginally reduce the height of reflux episodes in the esoph-agus but may relieve symptoms temporarily.( Tighe MP, et al ,2009). Sucralfate is a combination of sucrose, sulfate, and alumi-num. In an acidic environment, it forms a gel that binds to the exposed ...
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[109 Pages Report] Check for Discount on Global Alginate Dressing Market Professional Survey Report 2017 report by QYResearch Group. This report studies Alginate Dressing in Global market, especially in...
Alginic acid, an aa cried algin or alginate, is an anionic polysaccharide distributit widely in the cell walls o broun algae, whaur through bindin wi watter it furms a viscous gum. In extractit furm it absorbs watter quickly; it is capable o absorbin 200-300 times its ain wicht in watter.[1] Its colour ranges frae white tae yellaeish-broun. It is sauld in filamentous, granular or poudered furms.. ...
Immobilized yeast for the production of alcoholic beverages is produced by forming calcium alginate beads containing yeast, hardening the beads for 30 to 180 minutes in a CaCl|sub|2|/sub| solution, wa
Dear All, is there anyone out there who has made alginate beads? The kind of beads people immobilize cells with? My plan is to make an alginate column, but I am a bit lost trying to get this stuff to make beads which are free flowing. I can make an inconvenient lump by adding calcium chloride, but no nice small beads! Regards, Mike ...
Osteogenic differentiation of mesenchymal stem cells has been extensively investigated with regards to different aspects, including the analysis of cell intracellular and extracellular proteome, cell gene expression pattern, and morphology. During the osteogenic differentiation, osteoblasts produce and release specific proteins, like osteocalcin and osteopontin. Simultaneously, cells produce the extracellular matrix (ECM) that resembles the bone ECM, with high quantity of calcium and phosphorus. We focused on the ultrastructural changes occurring during the osteogenic differentiation of MSC cultured in alginate hydrogel. The analysis revealed that during the osteogenic differentiation the most of cells become dead, and these dead cells contain large quantities of calcium and deposition is strictly connected with the cellular death and small membrane vesicles released by cells. Cell organelles were not present within differentiated cells, while in cells from non-osteogenic group the cellular
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alginic acid definition: An insoluble colloidal acid by means of a carboxylated polysaccharide thats abundant in the mobile wall space of brown algae.; A gum (a carboxylated polysaccharide), obtained…
Gentaur molecular products has all kinds of products like :search , Nacala \ Alginic Acid \ 01227-62 for more molecular products just contact us
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The use of 3-dimensional (3D) matrices for cell culture has become popular as it provides more representative models of the biological situation in tissues, organs and tumors than the traditional 2D cell culture. NovaMatrix®-3D is an alginate-based cell culture system comprising an alginate foam matrix and an alginate immobilization solution. The cells are first suspended in the alginate solution and applied to the foam. This induces in situ gelation by diffusion of calcium ions to the added alginate and the cells are immobilized inside the pores of the foam. Alginate is not recognized by cell receptors and is considered inert towards cells. Cells form 3-dimensional structures such as spheroids, and the system may be utilized as an in vitro tumor model. The growth of spheroids inside the 3D matrix can be determined by evaluating changes in spheroid volume. Hypoxic cells are more resistant towards traditional cancer treatments such as chemotherapy and radiation. This study used cells cultured in ...
Andrew J. Leech, A. Sprinkle, L. Wood, D.J. Wozniak, and D.E. Ohman. "The NtrC-family regulator AlgB, which controls alginate biosynthesis in mucoid Pseudomonas aeruginosa, binds directly to the algD promoter." Journal of Bacteriology. Vol. 190, (January 2008.): 581-589.. Belete, B., H. Lu, and D.J. Wozniak. "Pseudomonas aeruginosa AlgR regulates type IV pilus biosynthesis by activating expression of the fimU-pilVWXY1Y2E operon." Journal of Bacteriology. Vol. 190, (January 2008.): 2023-2030.. Robert W. Huigens, L. Ma, C. Gambino, P.D.R. Moeller, A. Basso, J. Cavanagh, D.J. Wozniak, and C. Melander. "Control of bacterial biofilms with marine alkaloid derivatives." Mol. BioSyst. Vol. 4, (January 2008.): 614-621.. Eric T. Weimer, H. Lu, D.J. Wozniak, and S.B. Mizel. "A vaccine containing OprF epitope 8, OprI, and type A and B flagellins provides protection against Pseudomonas aeruginosa." Infect. Immun.. Vol. 77, (January 2009.): 2356-2366.. M. Starkey, J. H. Hickman, L. Ma, N. Zhang, S. De Long, ...
ActivHeal Alginate is manufactured by processing natural elements found in seaweed to produce felt and rope dressings. The alginate fibres allow exudate to be absorbed into the dressing to form a cohe
ActivHeal Alginate is manufactured by processing natural elements found in seaweed to produce felt and rope dressings. The alginate fibres allow exudate to be absorbed into the dressing to form a cohe
In this research, a tissue engineering approach was investigated for the fabrication of homogeneous polymer/cells scaffolds suitable for applications in the clinic, in particular for the treatment of coronary disease and atherosclerosis. Sodium alginate chemically modified with an RGD-containing peptide promoting cell attachment was chosen as the natural polymer for the preparation of matrix/cells constructs. Several conditions were investigated to optimise the derivatisation of the biomaterial, and no major dissimilarities were identified among alginates with different guluronic/mannuronic acid compositions and viscosities during the derivatisation process. Successful incorporation of the GRGDY-pentapeptide onto the alginate was achieved. Amino acid analysis, which allowed a reliable quantification of the degree of peptide attached, demonstrated that the complete pentapeptidic sequence was present in the alginate after completion of the derivatisation procedure. However, a significant loss of ...
Citation: Sargus-Patino, C.N., Wright, E.C., Plautz, S.A., Miles, J.R., Vallet, J.L., Pannier, A.K. 2014. In vitro development of preimplantation porcine embryos using alginate hydrogels as a three-dimensional extracellular matrix. Reproduction, Fertility and Development. 26(7):943-953. Interpretive Summary: Between day 10 and 12 of gestation, porcine embryos undergo a dramatic morphological change, known as elongation, which is critical for recognition of pregnancy. Elongation deficiencies contribute to ~20% of embryonic loss, but exact mechanisms of elongation are poorly understood. Knowledge of these mechanisms could lead to the identification of factors that could be targeted to improve pregnancy outcomes. We have established a culture system using alginate hydrogel as a three-dimensional matrix that facilitates transformations in porcine embryo morphology, providing an in vitro model to study mechanisms of elongation. Day 9 embryos were assigned to an alginate hydrogel system or a control, ...
Biatain Alginate Ag is a highly absorbent silver alginate dressing for moderately to heavily exuding infected wounds; for sloughy wounds and cavity filling.
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In the modern world, controlled release of drug (CR) represent one of the very important areas in the medical field. These delivery systems offer numerous advantages, compared with conventional dosage forms, which include no side effects, improved efficacy, reduced toxicity, and improved patient compliance. The biodegradable polymers such sodium alginate (SA) and lignosulphonic acid (LS) are used, in order to investigate the CR of ciprofloxacin from SA/LS blends.
Westco Chemicals Inc. Chemical Distributor in Los Angeles California - Sodium Alginate Sodium Aluminum Phosphate Sodium Aluminum Sulfate Sodium Ascorbate
Page contains details about doxorubicin-glycyrrhetinic acid-loaded sodium alginate derivative-based nanoparticles . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
Sodium Alginate,Foodalga® 500 is a cream white powder whose appearance and smell are similar to sugar. It has a viscosity of approximately 400-600mPa.s ...
Surplus inventory offer of Manufacturer, Asia Radiator Additive. sodium alginate and mannitol. Overstock Radiator Additive inventory offer brand is Manufacturer, Asia
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Straight Handle Alginate Spatula is a plastic, broad blade spatula with medium flex used for alginate or cement. This dental tool is autoclavable to 270 ...
This page includes the following topics and synonyms: Alginate Dressing, Absorption Dressing, Absorptive Dressing, Dehydrating Dressing, Xerodressing, Algicell, Algisite M, Carboflex, Carraginate, Dermaginate, Kalginate, Kaltostat, Melgisorb, Sorbsan, Tegagen, Calcicare.
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How can something so common as milk turn instantly into a hard ball? Alginate. This critical ingredient is in everything from casts to Tums to silk screening gear. It is also the magic powder dropped into this kitchen sink science experiment. So, what is alginate? Sodium alginate is the sodium salt of alginic acid. Found naturally in seaweed, it is used here for its rapid agglutination properties. This process is accelerated by the vinegar. The sugar provides an additional binding agent for the balls. If youve tried this, wed love to hear about it. There might even be a free t-shirt in
As for Genehunter1s query... Aspergillie is again right on. We gave up on commercial so-called primary chondrocyte lines early on, because they lost their phenotype quickly. Some people also use various chondrosarcomas for matrix studies too, usually in the context of protein production for structural biology, but you dont want to read too much into normal cartilage biology from these cell types. Weve found that isolating our own from weanling rat rib/costal cartilage works best for our studies. This (Bone. 1988;9(3):185-94) is a GREAT paper describing this method in detail especially regarding ECM characteristics. We can maintain growth cells in monloayer for about 15 passages before they get weird. The phenotypic shift is quite dramatic...they become spindly rather than their normal rounded/cuboid morphology and they just suddenly stop proliferating at the usual pace of a 36-48h doubling time to a week or more, so Im reasonably sure theyve changed biologically. This is when I can them ...
poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3); α-L-guluronate lyase / G-specific alginate lyase (EC 4.2.2.11); poly-(MG)-lyase / MG-specific alginate lyase (EC 4.2.2.- ...
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The vessel-simulating flow-through cell (vFTC) has been used to examine release and distribution from drug-eluting stents in an in vitro model adapted to the stent placement in vivo. The aim of this s
The polysaccharide alginate is produced by brown algae and some bacteria and is composed of the two monomers, β-d-mannuronic acid (M) and α-l-guluronic acid (G). The distribution and composition of M/G are important for ...
Simpurity™ Alginate Wound Dressings have gel forming properties, conform to wound contours, and have strong wet tensile strength.
Page contains details about Ti3C2Tx-sodium alginate composite . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
A List with 1,031 English Words From Letters ALGINATES -- FindTheWord.info is a search engine for English words. FindTheWord.info searches for partial words (both crossword solver and part of word), help with cheating in Scrabble and Wordfeud, finds anagrams, palindromes, and words in word, and much more.The dictionary used contains more than 589,000 English words.
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Understanding the tolerance of Pseudomonas aeruginosa biofilms to antimicrobial therapy will aid in the treatment of chronic infections.
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Once infection is established and bacterial levels increase, P. aeruginosa must evade adaptive immunity. Within the CF lung major changes in the phenotype of P. aeruginosa occur. These result in the overproduction of the cell surface polysaccharide alginate, loss of the LPS O antigen (Campodónico et al., 2008), and accumulation of DNA mutations caused by mutations affecting the DNA repair enzyme MutS (Oliver and Mena, 2010). Thus, the organism presents an ever-changing set of antigens for adaptive host immune responses. As CF patients do not have known defects in adaptive immunity, why cant they mount an effective immune response to clear P. aeruginosa? Some do, as it was shown almost 25 yr ago that a small subset of CF patients ,12 yr old remained uninfected and had serum antibodies that recognize alginate and facilitate opsonic killing (Pier et al., 1987). This antibody is not found in other CF patients or even in healthy humans, most of whom produce natural nonopsonic/nonprotective ...
Bone morphogenetic proteins have been investigated intensively on both experimentally and clinically in orthopedic surgery. Especially in the early stages of bone regeneration, BMP-2 recruits local sources of skeletal progenitor cells and determines their course towards the osteogenic lineage. The current therapeutic application of BMP-2 for bone repair is nevertheless associated with unacceptable side effects and very high doses. The ideal carrier matrix should provide localized, retarded, and active BMP-2 delivery. Moreover, it should fulfill cell, attachment, proliferation, and differentiation requirements. We assumed that BMP-2 loaded microporous ß-TCP scaffolds, prepared by mixing BMP-2 solution with alginate and by loading the porous ceramics and hardening the alginate sol to a gel, would deliver a prolonged release system complying with these requirements. With this method, it is possible to include any concentration of one or more active ingredients in the scaffold. After the alginate ...
This invention relates to an alginate composition for coating food products, in particular cooked meat products such as sausages and a method for producing the alginate composition. Furthermore, the invention relates to a method for producing coated food products with the use of the alginate composition of the invention.
0014]Alginate is, according to the invention, primarily used as an alkaline or alkaline earth metal, eg. sodium, lithium, potassium, calcium etc. Sodium alginate is commonly preferred due to ease of solubility and inclusion hereof on the approved list (E401). Hence, sodium alginate is approved as an additive to foods. It is widely used in foods where a thickening of the food in question is desired. Usually, this involves an activated sodium alginate in contrast to this invention, wherein a dissolved or swelled, but inactivated, sodium alginate is used, which reacts upon a lowering of the pH value as happens in the stomach. Sodium alginate can be obtained in pharmaceutical and food approved varieties. Sodium alginate originates in seaweed, especially brown seaweed from the Norwegian Sea. A particular preferred alginate has a viscosity below 800 cP in a 4% aqueous solution measured at 20° C. on a Brookfield RVT viscometer, spindle no. 2 at 20 rpm. However, to obtain a sufficient gel strength when ...
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Thin films (2.0 nm) of copper on germanium internal reflection elements (IREs) were exposed to 10% gum arabic (aqueous solution), 2% alginic acid (aqueous solution), 1% bacterial culture supernatant (BCS, simulated seawater solution), and 0.5% Pseudomonas atlantica exopolymer (simulated seawater solution) and monitored in situ, real time, with the use of Fourier transform infrared/cylindrical internal reflection/attenuated total reflection spectroscopy as a function of time at ambient conditions. Ancillary graphite furnace atomic absorption spectroscopy was used to monitor the removal process of the copper thin film from the germanium IREs. Results indicate that some of the copper was removed from the Cu/Ge interface by all four polymers and incorporated into the polymer matrix. Thus, biocorrosion of copper was exhibited by the four polymers in the order of alginic acid , gum arabic , BCS , Pseudomonas atlantica exopolymer. The FT-IR/CIR/ATR technique can be successfully used to monitor ...
WORLD HEALTH ORGANIZATION WHO Food Additives Series 1972, No. 1 TOXICOLOGICAL EVALUATION OF SOME ENZYMES, MODIFIED STARCHES AND CERTAIN OTHER SUBSTANCES The evaluations contained in this publication were prepared by the Joint FAO/WHO Expert Committee on Food Additives which met in Rome, 16-24 June 19711 World Health Organization Geneva 1972 1 Fifteenth Report of the Joint FAO/WHO Expert Committee on Food Additives, Wld Hlth Org. techn. Rep. Ser., 1972, No. 488; FAO Nutrition Meetings Report Series, 1972, No. 50. The monographs contained in the present volume are also issued by the Food and Agriculture Organization of the United Nations, Rome, as FAO Nutrition Meetings Report Series, No. 50A (c) FAO and WHO 1972 PROPYLENE GLYCOL ALGINATE Biological data Biochemical aspects In vitro hydrolysis by simulated gastric and intestinal juices shows practically no effect of gastric juice, while intestinal juice hydrolyses 25 per cent. of the ester in 4 h., 65 per cent. in 12 h. and 80 per cent. in 24 h. ...
Sodium Alginate is the food preservative to this "RAW" product known as kelp noodles. Sodium Alginate is a natural source and is found and derived from brown seaweed also know as Laminaria hyperborea and Laminaria digitata.This is a food preservative to keep freshness. Do you know why? Well this Alginate that has a negative ionic charge which is good comes in a food grade source as a derivative from brown sea weed. This is a heavy procedure to produce this item. Kelp is harvested and made into mush from blending up heated and cleaned to be reformed into a matter of nice noodle shapes. By adding Sodium Alginate you get to reform material into a noodle with flexibility. Also this preservative will pull heavy metals and toxins from food source. It is also used as a supplement and hasnt been disapproved however look at the substance, it doesnt look that natural. Your food is packaged in a substance that moleculary binds tightly to such substances as strontium, calcium, barium, cadmium and radium. ...
Nanocomposite powders of gadolinium-doped ceria (GDC, Ce0.8Gd0.2O1.9) were synthesized via thermal treatment of the gel formed by contacting ionic solutions of sodium alginate as the jelling template and metal (gadolinium/cerium) nitrates as the starting material. The influence of calcination temperature and sodium alginate loading fraction on the properties of the synthesized GDC nanocomposite powders was investigated. Characterization was performed by energy dispersive X-ray spectroscopy, powder X-ray diffraction, thermogravimetric analysis, Field Emission Scanning Electron Microscopy, Fourier transformed infrared spectroscopy and nitrogen adsorption/desorption analysis. It was observed that the particle size and the surface area of the produced GDC nanocomposite powders are dominantly controlled by the calcination temperature, while the effect of sodium alginate loading fraction is limited by the range of the calcination temperature. In this study, the smallest mesoporous GDC nanocomposite ...
In this work, the brown algae Macrocystis pyrifera were pretreated with dilute sulfuric acid, water and three different types of ionic liquids (ILs): 1-ethyl-3-methylimidazolium acetate ([EMIM][OAc]), 1,5-diazabicyclo[4.3.0]non-5-ene acetate ([DBNH][OAc]) and 1,8-diazabicyclo-[5.4.0]-undec-7-ene-sulfurdioxide-monoethanolamine (DBU-MEA-SO2-SIL), to disassemble the complex polysaccharide structure. After each pretreatment procedure, enzymatic saccharification was performed to release the monosaccharides. The main building blocks of M. pyrifera were processed by derivatization via acid methanolysis and subjected to gas chromatographic analysis. It was found that the main constituents were alginate (60.6 wt.%) and cellulose (22.6 wt.%) of total carbohydrate content. The degradation of alginate requires the action of alginate lyase and oligoalginate lyase, which hydrolyze the main chain in a synergistic mechanism releasing uronic acid (unsaturated uronate). Upon saccharification of cellulose, ...
Gilead is developing a broad spectrum combination antibiotic (FTI) consisting of fosfomycin (an antibiotic with activity against gram-positive and gram-negative bacteria) and tobramycin (an aminoglycoside antibiotic with potent gram-negative activity) for treatment of patients with CF. FTI offers a potential option for treatment of CF lung infections. It is important to note that the concentration of tobramycin in FTI is lower than that of the approved dose of inhaled tobramycin alone, thereby demonstrating the potential of FTI to minimize long-term toxicity from repeated exposure to aminoglycosides like tobramycin. This study will evaluate the safety and efficacy of 2 dose combinations of fosfomycin/tobramycin for inhalation (FTI), following a 28-day course of Aztreonam for Inhalation (AZLI) in patients with cystic fibrosis and Pseudomonas aeruginosa lung infection ...
Natural antacids, such as calcium carbonate (Tums) or hydrotalcite, may provide short term relief from GERD.8. Drugs used to treat GERD may tend to deplete the body of certain nutrients-especially vitamin B12, but also folate and various minerals. Use of a multivitamin/multimineral supplement should correct this problem. For more information, see the articles on specific medications in the Drug Interactions section of this database. Deglycyrrhizinated licorice (DGL), a special form of the herb licorice, has shown some promise for the treatment of ulcers. A drug (carbenoxolone) that is similar to ingredients in licorice has been studied for the treatment of GERD, with good results.3-5. However, in these studies carbenoxolone was combined with other ingredients, including antacids and alginic acid. It is not clear that carbenoxolone alone will help GERD, and it is even less clear that licorice itself offers any benefit.. A popular over-the-counter drug for GERD, Gaviscon, contains a substance ...

Buy Dental Impression materials Online| Pinkblue.inBuy Dental Impression materials Online| Pinkblue.in

Modifications in alginates include dust free alginates, siliconized alginates and alginates containing disinfectants. ... ALGINATES:. Alginate is a widely used dental impression material. It is an irreversible elastic hydrocolloid which is a mucous ... Alginates are used to make preliminary impressions for dentulous and edentulous patients. The types of alginate include fast ... Dentsply Zelgan Plus Alginate 450gm Pack Regular Price ₹351 Special Price ₹338 ...
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Useful Information about Seaweed - Irish SeaweedsUseful Information about Seaweed - Irish Seaweeds

Raw material for seaweed polymers such as the alginate industry. *Cosmetics, body care, thalassotherapy and medicinal ...
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Essiac Tea (Tea Bag Cut)Essiac Tea (Tea Bag Cut)

... alginate (helps remove radioactive elements and heavy metals from cells), and sterols (reported to exhibit anti- ...
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Investigation of chitosan nanoparticles durability in combination with antioxidant-antibacterial fraction extracted from...Investigation of chitosan nanoparticles durability in combination with antioxidant-antibacterial fraction extracted from...

5.Venkatesan J, Bhatnagar I, Kim S-K. Chitosan-alginate biocomposite containing fucoidan for bone tissue engineering. Mar drugs ...
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Kombu (Laminaria digitata) - Atlantic Holdfast Seaweed CompanyKombu (Laminaria digitata) - Atlantic Holdfast Seaweed Company

It contains the highest levels of iodine and trace minerals of any seaweed we harvest, along with beneficial sodium alginate ... It contains the highest levels of iodine and trace minerals of any seaweed we harvest, along with beneficial sodium alginate ...
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Propylene glycol alginatePropylene glycol alginate

1,2-propane-diol ester of alginic acid; hydroxypropyl alginate; propane 1,2-diol alginate; INS No. 405. ... Propylene glycol alginate. Prepared at the 49th JECFA (1997). superseding specifications prepared at the 44th JECFA (1995),. ... Propylene glycol alginate is an ester of alginic acid in which some of the carboxyl groups are esterified with propylene glycol ...
more infohttp://www.fao.org/docrep/w6355e/w6355e0u.htm

Propylene glycol alginate - WikipediaPropylene glycol alginate - Wikipedia

Propylene glycol alginate (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E ... Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are ... a b Propylene glycol alginate, Food and Agriculture Organization of the United Nations ... What is the "propylene glycol alginate" found in salad dressings? at The Straight Dope ...
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Ingredients -- AlginatesIngredients -- Alginates

Alginates is made up of long chains of two monomers -- guluronic acid and manuronic acid. The chains can be made of all one ... Alginates are used as thickeners in fat substitutes, pet food, stuffed olives, onion rings, low fat sauces and spreads, and pie ... It also makes alginates useful as wound dressings, where they absorb fluids, and stop bleeding, and act as a scaffold. ... Propylene glycol alginate is stable in acids, and is used to keep the foamy head on beers. ...
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Video on alginatesVideo on alginates

Heres some pictures and a video of my first experiments with sodium alginate and spherification. I used sodium alginate from ... Sodium alginate is water soluble and can be mixed with many different fruit/vegetable juices and purés. When dripped into a ... When alginate is coordinated to sodium, its a very flexible chain. When sodium is replaced by calcium however, each calcium ... Chef Simon (French, click here for babelfish translation) has a nice page on alginates as well. Another french page here (with ...
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Alginate DressingAlginate Dressing

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sodium alginate | NISE Networksodium alginate | NISE Network

Exploring Fabrication - Gummy Capsules" lets visitors make self-assembled polymer spheres. They learn that self-assembly is a process by which molecules and cells form themselves into functional structures, and that self-assembly is used to make nanocapsules that can deliver medication ...
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Melgisorb Alginate DressingMelgisorb Alginate Dressing

Molnlycke Melgisorb® Ag Calcium Alginate Dressing is a highly absorbent, alginate dressing with CMC and ionic silver that kills ... The superb, wet strength of these alginate fibers do not allow the dressing to disintegrate in the wound bed so it may be ... When absorbing, the alginate fibers form a soft, moist gel providing a moist environment conductive to wound healing ... Melgisorb Ag is a highly absorbent alginate dressing with CMC and ionic silver that kills bacteria for up to four days. ...
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CM alginate dressingCM alginate dressing

... from Ningbo Chinmed Technology Co., Ltd on TopTenWholesale.com. This supplier is located in Ningbo, China ... CM Alginate is a soft, highly absorbent dressing that quickly forms a hydrophilic gel and cover the wound bed. Outstanding ...
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Sodium Alginate ManufacturingSodium Alginate Manufacturing

ArtMolds has a graphical presentation and explanation of how sodium silicate or sodium alginates are manufactured. Learn about ... HOW SODIUM ALGINATE IS MADE. The processes for the manufacture of sodium alginate from brown seaweeds fall into two categories ... To extract the alginate in the seaweed caustic soda is added to convert the seaweed to water-soluble sodium alginate. ... The aqueous alginate solution is further processed through a clarification procedure. Since the aqueous alginate solution is ...
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Fat-busting seaweed: Scientists identify fat-blocking seaweed alginatesFat-busting seaweed: Scientists identify fat-blocking seaweed alginates

Alginates isolated from certain types of seaweed may have potential in weight loss supplements and foods, according to new ... The team used bread as a vehicle for the delivery of the alginate a further during trial - finding that even a small amount ... "Method for quantifying alginate and determining release from a food vehicle in gastrointestinal digesta"​. Authors: David ... The study, published in Food Chemistry​, shows that alginate from sea kelp can suppress the digestion of fat in the gut - ...
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Browse fuzing.com to find sodium alginate sellers, suppliers, wholesalers, companies, manufacturers, exporters, factories. ... sodium alginate. You May Also Be Interested In: alginate color paste printing thickener sodium alginate thickener NDY printing ... 6. Lower price: about 3000RMB/t less than sodium alginate. Meanwhile, NDY brings similar softness as sodium alginate on ... NDY thickener has a lot of advantages over widely used thickener -- sodium alginate:. 1. Over 10~20% higher color yield, save a ...
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Calcium alginate applicators permit superior culture isolation from areas such as the eyes, ears, nasopharynx, urethra and ... Calcium alginate fibers lack fatty acids that inhibit many gonorrhea strains. *Calcium alginate fibers are slowly dissolved by ... Puritan™ Calcium Alginate Swabs Specimen collection and wound care; Wood shaft, Type 2; Shaft dimensions: 6 L x 0.10 Diameter ... Calcium alginate applicators permit superior culture isolation from areas such as the eyes, ears, nasopharynx, urethra and ...
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Iron & Alginate Study - Full Text View - ClinicalTrials.govIron & Alginate Study - Full Text View - ClinicalTrials.gov

The investigators will use alginate, in the form of alginate beads, as a protective barrier for soluble iron gluconate. It has ... iron gluconate incorporated into alginate beads,ferrous gluconate incorporated into alginate beads given with calcium, and ... Dietary Supplement: alginate beads with ferrous gluconate in presence of calcium After insertion of the cannula and collection ... Alginate inhibits iron absorption from ferrous gluconate in a randomized controlled trial and reduces iron uptake into Caco-2 ...
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Alginates & Derivatives Market by Type, Application, Region - 2019 | MarketsandMarketsAlginates & Derivatives Market by Type, Application, Region - 2019 | MarketsandMarkets

150 Pages Report]Alginates & Derivatives Market categorizes the global market by Type (Sodium Alginate, Calcium Alginate, ... Sodium Alginate *Calcium Alginate *Potassium Alginate *PGA *Others (ammonium alginate, magnesium alginate, zinc alginate, ... Others: Ammonium alginate, magnesium alginate, zinc alginate, alginic acid, triethanolamine alginate, and value-added alginates ... 7.2 Alginates & Derivatives Market, By Type 7.2.1 Sodium Alginate. 7.2.2 Calcium Alginate. 7.2.3 Potassium Alginate. 7.2.4 PGA ...
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Sodium Alginate SH | The WoolerySodium Alginate SH | The Woolery

... sodium alginate is a high viscosity, low solids thickener for all dyes. Primarily used for cotton but is suitable for silk and ... In addition to its textile application, sodium alginate is used as a stabilizer for ice cream, yogurt, cream, and cheese. It ... In addition to its textile application, sodium alginate is used as a stabilizer for ice cream, yogurt, cream, and cheese. It ... Extracted from brown seaweed, sodium alginate is a high viscosity, low solids thickener for all dyes. Primarily used for cotton ...
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AlgiSite M Calcium Alginate DressingAlgiSite M Calcium Alginate Dressing

Soft and conformable, AlgiSite M Calcium Alginate Dressing can be be cut and folded to fit unique wound sizes. Buy your ... AlgiSite M Calcium Alginate Dressing is designed for moist wound management of exuding wounds. ... As the AlgiSite ® M Calcium Alginate Dressing forms its soft gel, the alginate dressing creates moist environment at the wound ... AlgiSite ® M Calcium Alginate Dressing can be molded, folded, or cut to fit the shape and size of the wound. As the fibers gel ...
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  • The global alginates & derivatives market is projected to reach a value of $409.2 million by 2019 growing at a CAGR of 3.8% from 2014 to 2019. (marketsandmarkets.com)
  • The Commission said that clearance of DuPonts acquisition of the FMC Health and Nutrition business is conditional on the divestment of DuPont's global alginates business. (nutraingredients.com)
  • "DuPont offered to divest its global alginates business, including all tangible and intangible assets for the sourcing, development, manufacturing, packaging or sale of alginates," ​ said the EC. (nutraingredients.com)
  • The study, published in Food Chemistry ​, shows that alginate from sea kelp can suppress the digestion of fat in the gut - opening up 'exciting possibilities' for making everyday foods healthier. (nutraingredients.com)
  • Update: The Frog Blog has nice posts with pictures showing how Jay Veregge and Joel Robuchon utilize alginate gels. (khymos.org)
  • Cell adhesion studies of mouse myoblasts (C2C12) and human dental stem cells (RP89) to gels containing various amounts of GRGDSP coupled alginate demonstrated the bioactivity of the material where RP89 cells needed higher peptide concentrations to adhere. (bibsys.no)
  • Peptide coupled alginates obtained by chemical functionalization of alginates are commonly used as scaffold materials for cells in regenerative medicine and tissue engineering. (bibsys.no)
  • In addition to its textile application, sodium alginate is used as a stabilizer for ice cream, yogurt, cream, and cheese. (woolery.com)
  • The coupling efficiency was to some extent dependent on alginate composition, being most efficient on mannuronan. (bibsys.no)
  • By way of using in production and application, NDY thickener was significantly higher than the cost advantages of alginate and was a completely substitution of sodium alginate. (fuzing.com)
  • Extracted from brown seaweed, sodium alginate is a high viscosity, low solids thickener for all dyes. (woolery.com)
  • In the form of fibres trapped in a wound, alginate is readily biodegradable and can be rinsed away with saline irrigation. (wikipedia.org)
  • In certain circumstances, P. aeruginosa produces an alginate lyase enzyme which cleaves the polymer into short oligosaccharides. (nih.gov)
  • In enzymology, an alginate synthase (EC 2.4.1.33) is an enzyme that catalyzes the chemical reaction GDP-D-mannuronate + (alginate)n ⇌ {\displaystyle \rightleftharpoons } GDP + (alginate)n+1 Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP and (alginate)n+1. (wikipedia.org)
  • The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. (wikipedia.org)
  • The video shows how a red beet paste mixed with alginate solidifies when dripped into a solution of calcium lactate (this solution is normally clear, the yellow colour comes from extensive use). (khymos.org)
  • Sodium alginate is used to thicken the dye to a paste consistency for printing and hand painting. (misterart.com)
  • The seaweed extract is filtered to separate the sodium alginate solution from the cellulose contained in the fibrous seaweed residue. (artmolds.com)
  • The aim of this project is to measure the effect of alginate on iron absorption from ferrous gluconate and assess the potential modulating effect of calcium on iron absorption in the presence and absence of alginate. (clinicaltrials.gov)
  • Study to Measure the Absorption of Iron From Ferrous Gluconate Incorporated Into Alginate Beads. (clinicaltrials.gov)
  • Absorption will be assessed in response to four test meals as follows: unprotected ferrous gluconate, iron gluconate incorporated into alginate beads,ferrous gluconate incorporated into alginate beads given with calcium, and unprotected ferrous gluconate given with calcium. (clinicaltrials.gov)
  • The gelling properties of alginates are attributed to the presence of calcium ions that help form a slow degradeable cross-linked polymer gel. (wikipedia.org)
  • Globally, the alginates & derivatives market is driven by growing demand for sodium alginate, which is used in various industrial applications such as textile, paper, ceramics, cosmetics, pharmaceuticals, along with the food & beverage industry. (marketsandmarkets.com)
  • After insertion of the cannula and collection of baseline blood sample a single dose of approximately 20mg of iron as ferrous gluconate incorporated into alginate beads (approximately 22.2g)and added to cola jelly (200ml) will be given to the volunteer together with 3 placebo capsules (each containing 50mg of dextrose)and cola drink (200ml). (clinicaltrials.gov)
  • Alginate serves to protect the bacteria from adversity in its surroundings and also enhances adhesion to solid surfaces. (nih.gov)
  • This negates the anchoring properties of the alginate and results in increased detachment of the bacteria away from the surface, allowing them to spread and colonize new sites. (nih.gov)