Aleutian Mink Disease Virus
Aleutian Mink Disease
A slow progressive disease of mink caused by the ALEUTIAN MINK DISEASE VIRUS. It is characterized by poor reproduction, weight loss, autoimmunity, hypergammaglobulinemia, increased susceptibility to bacterial infections, and death from renal failure. The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are particularly susceptible.
Mink
Parvoviridae
Parvovirus
Newcastle disease virus
Cats
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Virus Replication
Foot-and-Mouth Disease Virus
Borna disease virus
A species in the genus Bornavirus, family BORNAVIRIDAE, causing a rare and usually fatal encephalitic disease in horses and other domestic animals and possibly deer. Its name derives from the city in Saxony where the condition was first described in 1894, but the disease occurs in Europe, N. Africa, and the Near East.
Vacuum
gamma-Globulins
Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.
Nova Scotia
A province of eastern Canada, one of the Maritime Provinces with NEW BRUNSWICK; PRINCE EDWARD ISLAND; and sometimes NEWFOUNDLAND AND LABRADOR. Its capital is Halifax. The territory was granted in 1621 by James I to the Scotsman Sir William Alexander and was called Nova Scotia, the Latin for New Scotland. The territory had earlier belonged to the French, under the name of Acadia. (From Webster's New Geographical Dictionary, 1988, p871 & Room, Brewer's Dictionary of Names, 1992, p384)
Counterimmunoelectrophoresis
Mephitidae
Physiological Phenomena
Vapor Pressure
Myotonia Congenita
Inherited myotonic disorders with early childhood onset MYOTONIA. Muscular hypertrophy is common and myotonia may impair ambulation and other movements. It is classified as Thomsen (autosomal dominant) or Becker (autosomal recessive) generalized myotonia mainly based on the inheritance pattern. Becker type is also clinically more severe. An autosomal dominant variant with milder symptoms and later onset is known as myotonia levior. Mutations in the voltage-dependent skeletal muscle chloride channel are associated with the disorders.
Quercus
Prussia
Peer Review
An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.
Andersen Syndrome
A form of inherited long QT syndrome (or LQT7) that is characterized by a triad of potassium-sensitive periodic paralysis, VENTRICULAR ECTOPIC BEATS, and abnormal features such as short stature, low-set ears, and SCOLIOSIS. It results from mutations of KCNJ2 gene which encodes a channel protein (INWARD RECTIFIER POTASSIUM CHANNELS) that regulates resting membrane potential.
Peer Review, Health Care
The concurrent or retrospective review by practicing physicians or other health professionals of the quality and efficiency of patient care practices or services ordered or performed by other physicians or other health professionals (From The Facts On File Dictionary of Health Care Management, 1988).
Enterococcus faecalis
Ketoglutaric Acids
National Institutes of Health (U.S.)
Wuchereria bancrofti
Hypergammaglobulinemia
PubMed
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Acanthaceae
A plant family of the order Lamiales. It is characterized by simple leaves in opposite pairs, cystoliths (enlarged cells containing crystals of calcium carbonate), and bilaterally symmetrical and bisexual flowers that are usually crowded together. The common name for Ruellia of wild petunia is easily confused with PETUNIA.
Hexokinase
An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-Glucose, D-mannose, D-fructose, sorbitol, and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase. (From Enzyme Nomenclature, 1992) EC 2.7.1.1.
Publishing
MEDLINE
Serial Publications
Biological Science Disciplines
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.
Parvovirus, Canine
Parvovirus B19, Human
Feline panleukopenia virus
A species of PARVOVIRUS infecting cats with a highly contagious enteric disease. Host range variants include mink enteritis virus, canine parvovirus (PARVOVIRUS, CANINE), and raccoon parvovirus. After infecting their new hosts, many of these viruses have further evolved and are now considered distinct species.
Oropharynx
Identification of a cell surface protein from Crandell feline kidney cells that specifically binds Aleutian mink disease parvovirus. (1/84)
Aleutian mink disease parvovirus (ADV) is the etiological agent of Aleutian disease of mink. The acute disease caused by ADV consists of permissive infection of alveolar type II cells that results in interstitial pneumonitis. The permissive infection is experimentally modeled in vitro by infecting Crandell feline kidney (CrFK) cells with a tissue culture-adapted isolate of ADV, ADV-G. ADV-G VP2 empty virions expressed in a recombinant baculovirus system were analyzed for the ability to bind to the surface of CrFK cells. Radiolabeled VP2 virions bound CrFK cells specifically, while they did not bind either Mus dunni or Spodoptera frugiperda cells, cells which are resistant to ADV infection. The binding to CrFK cells was competitively inhibited by VP2 virions but not by virions of cowpea chlorotic mottle virus (CCMV), another unenveloped virus similar in size to ADV. Furthermore, preincubation of CrFK cells with the VP2 virions blocked infection by ADV-G. The VP2 virions were used in a virus overlay protein binding assay to identify a single protein of approximately 67 kDa, named ABP (for ADV binding protein), that demonstrates specific binding of VP2 virions. Exogenously added VP2 virions were able to competitively inhibit the binding of labeled VP2 virions to ABP, while CCMV virions had no effect. Polyclonal antibodies raised against ABP reacted with ABP on the outer surface of CrFK cells and blocked infection of CrFK cells by ADV-G. In addition, VP2 virion attachment to CrFK cells was blocked when the VP2 virions were preincubated with partially purified ABP. Taken together, these results indicate that ABP is a cellular receptor for ADV. (+info)Three-dimensional structure of Aleutian mink disease parvovirus: implications for disease pathogenicity. (2/84)
The three-dimensional structure of expressed VP2 capsids of Aleutian mink disease parvovirus strain G (ADVG-VP2) has been determined to 22 A resolution by cryo-electron microscopy and image reconstruction techniques. A structure-based sequence alignment of the VP2 capsid protein of canine parvovirus (CPV) provided a means to construct an atomic model of the ADVG-VP2 capsid. The ADVG-VP2 reconstruction reveals a capsid structure with a mean external radius of 128 A and several surface features similar to those found in human parvovirus B19 (B19), CPV, feline panleukopenia virus (FPV), and minute virus of mice (MVM). Dimple-like depressions occur at the icosahedral twofold axes, canyon-like regions encircle the fivefold axes, and spike-like protrusions decorate the threefold axes. These spikes are not present in B19, and they are more prominent in ADV compared to the other parvoviruses owing to the presence of loop insertions which create mounds near the threefold axes. Cylindrical channels along the fivefold axes of CPV, FPV, and MVM, which are surrounded by five symmetry-related beta-ribbons, are closed in ADVG-VP2 and B19. Immunoreactive peptides made from segments of the ADVG-VP2 capsid protein map to residues in the mound structures. In vitro tissue tropism and in vivo pathogenic properties of ADV map to residues at the threefold axes and to the wall of the dimples. (+info)Replication of Aleutian mink disease parvovirus in vivo is influenced by residues in the VP2 protein. (3/84)
Aleutian mink disease parvovirus (ADV) is the etiological agent of Aleutian disease of mink. Several ADV isolates have been identified which vary in the severity of the disease they elicit. The isolate ADV-Utah replicates to high levels in mink, causing severe Aleutian disease that results in death within 6 to 8 weeks, but does not replicate in Crandell feline kidney (CrFK) cells. In contrast, ADV-G replicates in CrFK cells but does not replicate in mink. The ability of the virus to replicate in vivo is determined by virally encoded determinants contained within a defined region of the VP2 gene (M. E. Bloom, J. M. Fox, B. D. Berry, K. L. Oie, and J. B. Wolfinbarger. Virology 251:288-296, 1998). Within this region, ADV-G and ADV-Utah differ at only five amino acid residues. To determine which of these five amino acid residues comprise the in vivo replication determinant, site-directed mutagenesis was performed to individually convert the amino acid residues of ADV-G to those of ADV-Utah. A virus in which the ADV-G VP2 residue at 534, histidine (H), was converted to an aspartic acid (D) of ADV-Utah replicated in CrFK cells as efficiently as ADV-G. H534D also replicated in mink, causing transient viremia at 30 days postinfection and a strong antibody response. Animals infected with this virus developed diffuse hepatocellular microvesicular steatosis, an abnormal accumulation of intracellular fat, but did not develop classical Aleutian disease. Thus, the substitution of an aspartic acid at residue 534 for a histidine allowed replication of ADV-G in mink, but the ability to replicate was not sufficient to cause classical Aleutian disease. (+info)Unusual, high genetic diversity of Aleutian mink disease virus. (4/84)
The genetic diversity of Aleutian mink disease virus (AMDV) was examined. Sequences obtained from 35 clinical samples were compared with five published sequences. An unusual, high genetic variability was revealed. Three phylogenetic subgroups of AMDV were identified, and the presence of more than one genotype at some farms was detected. (+info)Replication of Aleutian mink disease parvovirus in mink lymph node histocultures. (5/84)
Aleutian mink disease parvovirus (ADV), causes an immune disorder with a persistent infection of lymphoid organs in adult mink. We studied replication of ADV in gel-supported histocultures prepared from adult mink mesenteric lymph node (MLN). Evidence of virus replication in the histocultures was first observed by indirect immunofluorescence 72 h after incubation with virus. Cells resembling lymphocytes and macrophages contained both ADV capsid (VP2) and nonstructural (NS1 and NS2) proteins, and were present in a distribution suggestive of infected cells within germinal centres. ADV replicative form and encapsidated virion DNA were also detected in infected histocultures at time-points after 72 h. In addition, we were able to passage ADV-Utah to a new round of histocultures. These results suggested that the infected cells were actual target cells for ADV replication and that productive ADV-Utah replication, complete with the generation of virus, was occurring in the histocultures. The mink MLN histocultures provide a system to study the replication and molecular pathogenesis of ADV in target tissues. (+info)Nonsuppurative meningoencephalitis associated with Aleutian mink disease parvovirus infection in ranch mink. (6/84)
Severe nonsuppurative meningoencephalitis associated with Aleutian mink disease parvovirus (ADV) infection was observed in adult ranch mink. Brain lesions included severe, locally extensive to coalescing lymphoplasmacytic meningoencephalitis with accompanying gliosis, satellitosis, and mild extension of inflammation into the leptomeninges. ADV was identified in mesenteric lymph node, spleen, brain, and liver of affected mink by polymerase chain reaction techniques. Sequences of the ADV isolate (TH5) revealed 2 unique residues in the region of the viral genome that determines pathogenicity. These findings suggest that certain strains of ADV may preferentially cause disease in the nervous system. ADV infection should be considered in the differential diagnosis of neurologic disorders in mink. (+info)Spontaneous Aleutian disease in a ferret. (7/84)
A 3-year-old female ferret died five days after admission to a veterinary clinic for treatment of acute dyspnea and posterior paresis. Blood chemistry showed no hypergammaglobulinemia. Histopathological examination revealed mild to severe inflammatory infiltrates, composed mostly of plasma cells, in multiple organs. Lesions were especially severe in the kidneys, where focal segmental membranous glomerulopathy was also present. In the liver, in addition to lymphocytic and plasmacytic infiltration in periportal areas, dilatation and proliferation of the bile ducts were seen. On analysis of PCR products, using primers directed against the gene encoding Aleutian disease (AD) viral capsid and formalin-fixed kidney samples, we detected a single band of about 400 bp, specific to the AD virus. (+info)Nucleotide sequence and polymerase chain reaction/restriction fragment length polymorphism analyses of Aleutian disease virus in ferrets in Japan. (8/84)
Two ferrets with spontaneous Aleutian disease (AD) were found in Japan. The diagnosis was verified by polymerase chain reaction (PCR) amplification of part of the capsid gene specific to AD virus (ADV). The nucleotide sequences (365 bp in length) of the amplified fragments from the 2 ferrets differed by a single nucleotide, producing an amino acid alteration. Compared with other types of ADV, these isolates had 96% sequence similarity to a published ferret ADV (FADV) in contrast to <91% homology to various types of mink ADV (MADV). The phylogenetic tree of ADVs indicates that these 2 isolates and the published FADV belong to the same genetic group and definitely are divergent from MADVs. The predicted amino acid sequence of the hypervariable segment in the capsid gene was conserved among the 3 types of FADV. These results indicated that the 2 isolates found in Japan were new DNA types of FADV and could have been derived from FADV(s). A restriction fragment length polymorphism (RFLP) method to distinguish the ferret types of ADV from the mink types of ADV was developed on the basis of differences in their nucleotide sequences. Digestion of the PCR products with Afal or ScaI provided different cleavage patterns for FADV and MADV. This PCR/RFLP analysis of the ADV capsid gene will be a valuable asset for diagnosis of this virus infection in ferrets. (+info)
Monitoring chronic infection with a field strain of Aleutian mink disease virus - Danish National Research Database-Den Danske...
Aleutian mink disease virus in furbearing mammals in Nova Scotia, Canada | Acta Veterinaria Scandinavica | Full Text
Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme<...
ANTIBODIES TO ALEUTIAN MINK DISEASE PARVOVIRUS IN FREE-RANGING EUROPEAN MINK (MUSTELA LUTREOLA) AND OTHER SMALL CARNIVORES FROM...
No questions in Aleutian Mink Disease - lookformedical.com
Aleutian Mink Disease | Harvard Catalyst Profiles | Harvard Catalyst
Background Mink enteritis pathogen (MEV) causes mink viral enteritis, an acute | immune-source.com
Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits....
The effect of antimicrobial treatment on mortality associated with urinary tract disease in mink kits ( Neovison vison ) | Acta...
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THE BACK STORY -: Dont Blink, Its Another MINK!
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Studies on the pathogenesis of Aleutian disease in mink. VIII. Depression of antibody formation against horseradish peroxidase ...
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Molecular Mechanisms
25 mm mink trepalnice večino magnetni trepalnice paket debelo oči, trepalnice dramatično umetne trepalnice 30 parov ročno...
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Amdoparvovirus
Aleutian+Mink+Disease at the US National Library of Medicine Medical Subject Headings (MeSH) Aleutian+Mink+Disease+Virus at the ... Aleutian mink disease virus). Diseases associated with this genus include progressive disorder of immune system. Group: ssDNA ... Cheng F, Chen AY, Best SM, Bloom ME, Pintel D, Qiu J (March 2010). "The capsid proteins of Aleutian mink disease virus activate ... "Driving forces behind the evolution of the Aleutian mink disease parvovirus in the context of intensive farming". Virus ...
Parvovirus
Aleutian mink disease virus), vii) Aveparvovirus (e.g. chicken parvovirus) and viii) Copiparvovirus (e.g. bovine parvovirus 2). ... A different parvovirus causes aleutian disease in mink and other mustelids, characterized by lymphadenopathy, splenomegaly, ... They are classified as group II viruses in the Baltimore classification of viruses. Parvoviruses are among the smallest viruses ... Mink enteritis virus is similar in effect to feline panleukopenia, except that it does not cause cerebellar hypoplasia. ...
Ferret health
Aleutian disease virus (ADV) is a parvovirus discovered among mink in the Aleutian Islands in the early 20th century. In ... There is no cure or vaccine for the disease, and ferrets may carry the virus for months or years without any signs. Canine ... It has also been suggested that there may be a hereditary component to adrenal disease. Adrenal disease is usually detected ... Ferrets treated for adrenal disease may temporarily have severe hair loss as their bodies recover from the disease. Insulinoma ...
List of MeSH codes (B04)
... aleutian mink disease virus MeSH B04.280.580.650.600.325 - feline panleukopenia virus MeSH B04.280.580.650.600.550 - mice ... aleutian mink disease virus MeSH B04.909.204.671.650.600.325 - feline panleukopenia virus MeSH B04.909.204.671.650.600.550 - ... border disease virus MeSH B04.820.250.700.150 - diarrhea viruses, bovine viral MeSH B04.820.250.700.150.100 - diarrhea virus 1 ... african horse sickness virus MeSH B04.820.630.550.100 - bluetongue virus MeSH B04.820.630.550.400 - hemorrhagic disease virus, ...
Aleutian disease
Once symptoms have been indicated, the mink is certain to die. A lethal infection in mink, the Aleutian disease virus lies ... Persson S, Jensen TH, Blomström AL, Appelberg MT, Magnusson U (2015-03-30). "Aleutian mink disease virus in free-ranging mink ... Aleutian Disease was first recognized in ranch-raised mink in 1956. The disease was so named because it was first found in mink ... Aleutian disease, also known as mink plasmacytosis, is a disease which causes spontaneous abortion and death in minks and ...
ADV
... in flow measurement Acoustic droplet vaporization Adventure type of visual novel Aleutian Disease Virus, a disease of ferrets ... and minks, or the virus that causes it Andover Airfield, Hampshire, UK (IATA airport code) Andover railway station, UK ( ...
Ochlerotatus
Sindbis virus[citation needed] Ochlerotatus fitchii - woodland mosquito Bites man, carries Aleutian mink disease, heartworm, ... heartworm Jamestown Canyon virus, La Crosse virus. West Nile virus[citation needed] Aedes churchillensis Aedes communis - ... woodland snow pool mosquito Bites man, carries California encephalitis virus, Jamestown Canyon virus, Sindbis virus[citation ... carries Ross River virus Ochlerotatus canadensis - woodland pool mosquito Bites man, carries California encephalitis virus, ...
List of MeSH codes (C02)
... aleutian mink disease MeSH C02.256.700.300 - erythema infectiosum MeSH C02.256.700.363 - feline panleukopenia MeSH C02.256. ... kyasanur forest disease MeSH C02.782.417.505 - lassa fever MeSH C02.782.417.560 - marburg virus disease MeSH C02.782.417.762 - ... border disease MeSH C02.782.350.675.106 - bovine virus diarrhea-mucosal disease MeSH C02.782.350.675.200 - classical swine ... marburg virus disease MeSH C02.782.580.600 - paramyxoviridae infections MeSH C02.782.580.600.080 - avulavirus infections MeSH ...
American mink
Aleutian disease European mink Sea mink Fur farming Reid, F.; Schiaffini, M.; Schipper, J. (2016). "Neovison vison". IUCN Red ... The American mink and European mink have both been found to transmit SARS-CoV-2, the virus that causes COVID-19. American minks ... Transmissible mink encephalopathy (TME) is a prion disease of mink, similar to BSE in cattle and scrapie in sheep. A 1985 ... Domestic mink are larger than wild mink, which may cause problems with the ecosystem when they escape. Minks are solitary, ...
Tern
Several species of terns have been implicated as carriers of West Nile virus. Terns and their eggs have long been eaten by ... ISBN 0-00-219728-6. Takken, Willem; Knols, Bart G J (editors) (2007). Emerging pests and vector-borne diseases in Europe. ... like the Aleutian tern, may wander far from land. The sooty tern is entirely oceanic when not breeding, and healthy young birds ... such as the American mink in Scotland, presents an unfamiliar threat. Adult terns may be hunted by owls and raptors, and their ...
Sea otter
Although disease has clearly contributed to the deaths of many of California's sea otters, it is not known why the California ... In the Aleutian Islands, a massive and unexpected disappearance of sea otters has occurred in recent decades. In the 1980s, the ... The extinct sea mink of northeastern North America is another mustelid that had adapted to a marine environment. Three ... "may be a newly identified animal host of influenza viruses". Sea otters have the thickest fur of any mammal, which makes them a ...
List of introduced species
"B-Virus and Free-Ranging Macaques, Puerto Rico". Emerging Infectious Diseases. 10 (3): 494-496. doi:10.3201/eid1003.030257. PMC ... American mink) from North America Procyon lotor (common raccoon) from North America Myocastor coypus (nutria) from South ... and Umnak Island in the Aleutian Archipelago from mainland Alaska Lepus europaeus (European hare) From Europe Oryctolagus ... Guyana and Suriname American mink Dog Cat Chital from Asia to Argentina, Brazil, Uruguay and Chile Elk from North America Red ...
Arctic fox
Arctic rabies virus. References. *^ a b c d Angerbjörn, A.; Hersteinsson, P.; Tannerfeldt, M. (2008). "Alopex lagopus". IUCN ... In the late 19th century, it was introduced into the Aleutian Islands southwest of Alaska. It mostly inhabits tundra and pack ... treating a population imperilled by disease". Oryx. 30 (4): 251-258. doi:10.1017/S0030605300021748.. ... European mink (M. lutreola). *Indonesian mountain weasel (M. lutreolina). *Black-footed ferret (M. nigripes) ...
Aleutian Mink Disease Virus and Humans - Volume 15, Number 12-December 2009 - Emerging Infectious Diseases journal - CDC
However, 2 mink farmers with vascular disease and microangiopathy similar to that in mink with Aleutian disease were found to ... These findings raise the suspicion that AMDV may play a role in human disease. ... Reports of a possible relationship between Aleutian mink disease parvovirus (AMDV) and human infection are rare. ... such as Aleutian mink disease virus (AMDV), cause a broad spectrum of diseases in animals and man. Acute disease manifests ...
Aleutian Mink Disease Virus and Humans - Volume 15, Number 12-December 2009 - Emerging Infectious Diseases journal - CDC
... such as Aleutian mink disease virus (AMDV), cause a broad spectrum of diseases in animals and man. Acute disease manifests ... Aleutian Mink Disease Virus and Humans. Emerging Infectious Diseases. 2009;15(12):2040-2042. doi:10.3201/eid1512.090514.. ... However, 2 mink farmers with vascular disease and microangiopathy similar to that in mink with Aleutian disease were found to ... Jepsen JR, dAmore F, Baandrup U, Clausen MR, Gottschalck E, Aasted B. Aleutian Mink Disease Virus and Humans. Emerg Infect Dis ...
Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme<...
Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme. Kopenhagen Fur Forskning. Faglig ... Kvisgaard, LK, Hansen, MS, Chriél, M, Larsen, LE & Hjulsager, CK 2018, Forsøg med inaktivering af aleutian mink disease virus ( ... Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme. In Kopenhagen Fur Forskning. ... title = "Fors{\o}g med inaktivering af aleutian mink disease virus (AMDV) i gylle ved h{\o}j PH eller varme", ...
Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits....
Aleutian Mink Disease. Aleutian Mink Disease Virus. Animals. Immunosorbent Techniques. Liver. Lung. Mink. Molecular Weight. ... Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. ... Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. ... Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. ...
Co-circulation of highly diverse Aleutian mink disease virus strains in Finland | Microbiology Society
... is the causative agent of Aleutian disease (AD), which affects mink of all genotypes and also infects other mustelids such as ... Mink in the wild carry viruses with high intra-host diversity and are occasionally even co-infected by two different strains, ... strains by sequencing the complete coding sequences of 31 strains from mink originating from farms differing in their virus ... The sequences demonstrate that the Finnish AMDV strains have considerable diversity, and that the virus has been introduced to ...
Restricted heterogeneity of the early antibody response to Aleutian disease virus in mink kits. - DRO
Aleutian Mink Disease. Aleutian Mink Disease Virus. Animals. Antibodies, Viral. Counterimmunoelectrophoresis. Electrophoresis, ... Restricted heterogeneity of the early antibody response to Aleutian disease virus in mink kits.. Alexandersen, Soren and Aasted ... Restricted heterogeneity of the early antibody response to Aleutian disease virus in mink kits. ... B 1986, Restricted heterogeneity of the early antibody response to Aleutian disease virus in mink kits., Acta Pathologica ...
Aleutian mink disease virus in furbearing mammals in Nova Scotia, Canada | Acta Veterinaria Scandinavica | Full Text
The mechanism of virus transmission between wildlife and captive mink and the effects of AMDV exposure on the viability of the ... Antibodies to AMDV were detected by CIEP in 16 of 56 (28.6%) mink and one of the 8 skunks (12.5%). Thirteen of the mink were ... Positive PCR or CIEP samples were detected in 56 of 60 (93.3%) American mink, 43 of 61 (70.5%) short-tailed weasels, 2 of 8 ( ... Positive CIEP or PCR animals were present in all nine counties from which mink or weasel samples were collected. The presence ...
Figure 1 - Aleutian Mink Disease Virus and Humans - Volume 15, Number 12-December 2009 - Emerging Infectious Diseases journal -...
Aleutian Mink Disease Virus and Humans Jørgen R. Jepsen. , Francesco dAmore, Ulrik Baandrup, Michael Roost Clausen, Elisabeth ... of abdominal aortic biopsy sample from 35-year-old mink farmer in Denmark who had been exposed to Aleutian mink disease ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ...
Monitoring chronic infection with a field strain of Aleutian mink disease virus - Danish National Research Database-Den Danske...
Aleutian mink disease virus (AMDV) readily spread within farmed mink and causes chronic infections with significant impacts for ... Aleutian mink disease virus; AMDV; Mink; PCR; Counter current immunoelectrophoresis; Chronic experimental infection; The ... Monitoring chronic infection with a field strain of Aleutian mink disease virus. * ... Four of 6 sapphire mink were infected indirectly via the AMDV inoculated wild type mink whereas the other 2 sapphire mink ...
Histopathologic and immunohistochemical lesions in liver of mink infected with Aleutian disease virus - Polish Journal of...
Histopathologic and immunohistochemical lesions in liver of mink infected with Aleutian disease virus - Polish Journal of ... Histopathologic and immunohistochemical lesions in liver of mink infected with Aleutian disease virus Journal title. Polish ... Histopathologic and immunohistochemical lesions in liver of mink infected with Aleutian disease virus. A. Valdovska; M. Pilmane ... Mink: Biology, health and disease, 21. ; S Hsu (1981), The use of antiavidin antibody and avidin-biotin - peroxidase complex in ...
Molecular epidemiology of Aleutian mink disease virus causing outbreaks in mink farms from Southwestern Europe: a retrospective...
Molecular epidemiology of Aleutian mink disease virus causing outbreaks in mink farms from Southwestern Europe: a retrospective ... Molecular epidemiology of Aleutian mink disease virus causing outbreaks in mink farms from ... [email protected]#Aleutian mink disease virus (AMDV) causes major economic losses in fur-bearing animal production. The control of ... helps assess the possible origin of AMDV infections in mink farms and improving the control and prevention of this disease. ...
Division of Intramural Research Laboratory Descriptions | NIH: National Institute of Allergy and Infectious Diseases
Models being examined include human, murine, and equine retroviruses; rabies virus; Aleutian disease virus of mink; and ... Laboratory of Infectious Diseases (LID) focuses on viral vaccine development, host immune response to viruses, and viral ... Laboratory of Viral Diseases. Laboratory of Viral Diseases (LVD) studies the basic mechanisms of viral entry into cells, ... Laboratory of Parasitic Diseases (LPD) conducts basic and clinical studies to prevent, control, and treat diseases caused by ...
Institut for Kemi og Biovidenskab - Publikationer
- Aalborg Universitets forskningsportal
Anders Gorm Pedersen - DTU
Evolutionary analysis of whole-genome sequences confirms inter-farm transmission of Aleutian mink disease virus Hagberg, Emma ... Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies Boyd, Mette ; ... frame next generation sequencing assay for genotyping and identification of resistance-associated variants in hepatitis C virus ...
Wildlife diseases
Aleutian mink disease virus in furbearing mammals in Nova Scotia, Canada Aleutian mink disease virus (AMDV) is widespread among ... Reports on the detection of viruses such as the isolation of an avian influenza virus in Norway for the first time, and the ... Wildlife Diseases. Here we present a collection of articles published in Acta Veterinaria Scandinavica advancing our knowledge ... Orf virus infection in Alaskan mountain goats, Dalls sheep, muskoxen, caribou and Sitka black-tailed deer The zoonotic Orf ...
Lise Kirstine Kvisgaard - DTU
Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme Kvisgaard, Lise Kirstine ; Hansen ... Forbedret diagnostik af mink enteritis virus (MEV) Kvisgaard, Lise Kirstine ; Holm, Elisabeth ; Chriél, Mariann ; Larsen, Lars ... Publisher: Kopenhagen Fur, Report name: Forbedret diagnostik af mink enteritis virus (MEV), pages: 101-104 ... Eksperimentel smitte af mink med plasmacytosevirus i foder Hjulsager, Charlotte Kristiane ; Lazov, Christina Marie ; Chriél, ...
Sektion for Virologisk Overvågning og Forskning
Aleutian mink disease virus (ADV). *Rabbit hemorragic disease virus (RHDV). I sektionen udføres der udover overvågning og ... Sektionen overvåger virus ved at udføre specialiseret karakterisering af cirkulerende virus i Danmark i forbindelse med ... Lasse Dam Rasmussen, Seniorforsker, Virus & Mikrobiologisk Specialdiagnostik / Virus Overvågning og Reference. T. 32689055 @. ... Sofie Elisabeth Midgley, Seniorforsker, Virus & Mikrobiologisk Specialdiagnostik / Virus Overvågning og Reference. T. 32683407 ...
Aleutian Mink Disease | Harvard Catalyst Profiles | Harvard Catalyst
A slow progressive disease of mink caused by the ALEUTIAN MINK DISEASE VIRUS. It is characterized by poor reproduction, weight ... "Aleutian Mink Disease" by people in Harvard Catalyst Profiles by year, and whether "Aleutian Mink Disease" was a major or minor ... The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are ... "Aleutian Mink Disease" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ...
The Big Picture Book of Viruses - ICTV
50.1.1.0.001 Type Species mice minute virus. 50.1.1.0.002 Species Aleutian mink disease virus This type of numbering system ... Viral Diseases - Virus Names - Virus Families - Virus Hosts - Viruses By Genome Type Big Picture Book of Viruses - FAQ - Submit ... Other species: 50.1.1.0.002 Aleutian mink disease virus; 50.1.1.0.003 bovine parvovirus; 50.1.1.0.004 canine minute virus; 50.1 ... Decimal code - a tool for virus classification. It is often difficult to uniquely identify each virus, because virus names for ...
Virology Journal 1/2017 | springermedizin.de
Outbreak tracking of Aleutian mink disease virus (AMDV) using partial NS1 gene sequencing. P. Ryt-Hansen, C.K. Hjulsager, E.E. ... Global phylogenetic analysis of contemporary aleutian mink disease viruses (AMDVs). P. Ryt-Hansen, E. E. Hagberg, M. Chriél, T ... Recombinant expression of beak and feather disease virus capsid protein and assembly of virus-like particles in Nicotiana ... A rapid virus-induced gene silencing (VIGS) method for assessing resistance and susceptibility to cassava mosaic disease. Getu ...
Biology Honors Theses and Research Papers
Sequence analysis of Aleutian Mink Disease Virus (AMDV) isolates in captive North American mink Vaughan, Cristina (2014) ... Aleutian mink disease virus (AMDV) is a member of the parvoviridae family which primarily affects mink, often resulting in ... The purpose of this study was to identify changes in protein expression that occur in the hippocampus in Alzheimers disease ( ... Bacterial wilt is a devastating disease affecting hundreds of species of plants and millions of people by destroying crops like ...
Browsing College of Agricultural and Life Sciences Honors and Undergraduate Research Program by Title
New DNA Viruses Identified in Patients with Acute Viral Infection Syndrome | Journal of Virology
... minute virus of canines; AMDV, Aleutian mink disease virus; MEV, mink enteritis virus; Kilrat, Kilham rat parvovirus; MVM, ... GB virus C/hepatitis G virus was identified in three individuals and hepatitis B virus in one individual. Three previously ... GB virus C (GBV-C)/hepatitis G virus (HGV) (22, 34), hantavirus (26), TT virus (TTV) (24, 27), and herpesviruses in monkeys (12 ... Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Science 271:505-508. ...
Pedersen Anders[au] - PubMed - NCBI
Evolutionary analysis of whole-genome sequences confirms inter-farm transmission of Aleutian mink disease virus. ... Virus Adaptation and Selection Following Challenge of Animals Vaccinated against Classical Swine Fever Virus. ... Acute Influenza A virus outbreak in an enzootic infected sow herd: Impact on viral dynamics, genetic and antigenic variability ... Donor Genotype in the Interleukin-7 Receptor α-Chain Predicts Risk of Graft-versus-Host Disease and Cytomegalovirus Infection ...
Sun Z[au] - PubMed - NCBI
Distemper virus as a cause of central nervous disease and death in badgers (Meles meles) in Denmark - DTU Orbit
Monitoring chronic infection with a field strain of Aleutian mink disease virus. Research output: Research - peer-review › ... Distemper virus as a cause of central nervous disease and death in badgers (Meles meles) in Denmark. Research output: Research ... Section of Fur Animal Diseases and Wildlife, Division of Poultry, Fish and Fur Animals, National Veterinary Institute, ... Risk factors for transmission of foot-and-mouth disease during an outbreak in southern England in 2007. Research output: ...
Parvovirus - Wikipedia
Aleutian mink disease virus), vii) Aveparvovirus (e.g. chicken parvovirus) and viii) Copiparvovirus (e.g. bovine parvovirus 2). ... A different parvovirus causes aleutian disease in mink and other mustelids, characterized by lymphadenopathy, splenomegaly, ... They are classified as group II viruses in the Baltimore classification of viruses. Parvoviruses are among the smallest viruses ... Mink enteritis virus is similar in effect to feline panleukopenia, except that it does not cause cerebellar hypoplasia. ...
Table of Contents - September 01, 1977, 119 (3) | The Journal of Immunology
Reduced Severity of Lesions in Mink Infected Transplacentally with Aleutian Disease Virus David D. Porter, Austin E. Larsen and ... Antibody Response to Simian Virus 40 Tumor Antigen in Nude Mice Reconstituted with T Cells Lucienne Cicurel and Carlo M. Croce ... The Role of T Cells in Anti-Herpes Simplex Virus Immunity Klaus Pfizenmaier, Hartmut Jung, Anna Starzinski-Powitz, Martin ... Appearance of Cytotoxic Cells within the Bronchus after Local Infection with Herpes Simplex Virus Robert Clancy, William E. ...
Parvovirus -- Britannica Online Encyclopedia
Type species of the Parvovirinae include minute virus of mice, human parvovirus, and Aleutian mink disease virus. Whereas many ... Parvovirus, any virus belonging to the family Parvoviridae. Parvoviruses have small nonenveloped virions (virus particles), and ... these strains are designated adenoassociated viruses (AAV). Densovirinae viruses are typically named for their insect hosts; ... species of Parvovirinae replicate autonomously, the genus Dependovirus contains viruses that replicate only in the presence of ...
Welcome to CDC stacks
Aleutian Mink Disease Virus and Humans Personal Author:. Jepsen, Jørgen R.; dAmore, Francesco; Baandrup, Ulrik; Clausen, ... However, 2 mink farmers with vascular disease and microangiopathy similar to that in mink with Aleutian disease were found to ... Reports of a possible relationship between Aleutian mink disease parvovirus (AMDV) and human infection are rare. ... is a pathogen that causes gastroenteritis and bloody diarrhea but can lead to severe disease, such as hemolytic uremic syndrome ...
AMDVAntibodiesGenomeInfection in minkStrainsFerretsParvovirusesMustelaNeovisonViralInfectsHumansProteinsInfectionsAdeno-assocLesionsParvovirinaeParvoviridaeMolecularMustelidsHuman parvovirusImmuneFarmsFerretSkunksReplicationFree-rangSequenceSusceptibleMechanismsDetectionChronic diseaseMortalityAcuteGeneSpeciesImmunoelectrophoresisCausative agentOutbreaksAmdoparvovirusWeaselGenomicOttersEmerging InfectioVirulentNucleic acidMiceTissueGenesLiverStrainInfectious diseaseAdultPersistentCharacterizationPathogenesisParticlesAvianMRNAMeSH
AMDV40
- Reports of a possible relationship between Aleutian mink disease parvovirus (AMDV) and human infection are rare. (cdc.gov)
- However, 2 mink farmers with vascular disease and microangiopathy similar to that in mink with Aleutian disease were found to have AMDV-specific antibodies and AMDV DNA. (cdc.gov)
- These findings raise the suspicion that AMDV may play a role in human disease. (cdc.gov)
- Autonomous parvoviruses, such as Aleutian mink disease virus (AMDV), cause a broad spectrum of diseases in animals and man. (cdc.gov)
- In adult mink, AD is a persistent, slowly progressive AMDV infection in which a dysregulated immune system and a postinfectious antibody response cause an immune complex-mediated vasculitis ( 2 ). (cdc.gov)
- Histopathologic features like those in AMDV-infected mink have been described for 2 patients in the early 1960s ( 10 ). (cdc.gov)
- however, injection of their antibody-positive blood into Aleutian mink caused neither lesions nor AMDV-antibody production ( 11 ). (cdc.gov)
- We report finding anti-AMDV antibodies and AMDV genome in tissue from 2 mink farmers with relevant virus exposure and clinical disease similar to that in mink with AD. (cdc.gov)
- Patient 1 was a mink farmer who had been exposed to AMDV-infected mink for 10 years. (cdc.gov)
- Aleutian mink disease virus (AMDV) is the causative agent of Aleutian disease (AD), which affects mink of all genotypes and also infects other mustelids such as ferrets, martens and badgers. (microbiologyresearch.org)
- Previous studies have investigated diversity in Finnish AMDV strains, but these studies have been restricted to small parts of the virus genome, and mostly from newly infected farms and free-ranging mustelids. (microbiologyresearch.org)
- Here, we investigated the diversity and evolution of Finnish AMDV strains by sequencing the complete coding sequences of 31 strains from mink originating from farms differing in their virus history, as well as from free-ranging mink. (microbiologyresearch.org)
- The sequences demonstrate that the Finnish AMDV strains have considerable diversity, and that the virus has been introduced to Finland in multiple events. (microbiologyresearch.org)
- Molecular characterization of the small nonstructural proteins of parvovirus Aleutian mink disease virus (AMDV) during infection. (microbiologyresearch.org)
- Aleutian mink disease virus (AMDV) is widespread among ranched and free-ranging American mink in Canada, but there is no information on its prevalence in other wild animal species. (biomedcentral.com)
- The presence of AMDV in so many species across the province has important epidemiological ramifications and could pose a serious health problem for the captive mink, as well as for susceptible wildlife. (biomedcentral.com)
- The mechanism of virus transmission between wildlife and captive mink and the effects of AMDV exposure on the viability of the susceptible species deserve further investigation. (biomedcentral.com)
- Information on the prevalence of AMDV in wildlife in Eastern Canada is limited to one report on the feral American mink[ 3 ]. (biomedcentral.com)
- The primary objective of this study was to survey the prevalence of AMDV in wild furbearing species in Nova Scotia (NS), the largest ranched mink pelt producing province in Canada. (biomedcentral.com)
- Aleutian mink disease virus (AMDV) readily spread within farmed mink and causes chronic infections with significant impacts for welfare and economy. (forskningsdatabasen.dk)
- In the present study a currently circulating Danish AMDV strain was used to induce chronic experimental infection of farmed mink.PCR was used to detect viral DNA in full blood, organs, faeces and oro-nasal swabs weekly for the first 8 weeks and then biweekly for another 16 weeks after AMDV challenge inoculation of wild type mink. (forskningsdatabasen.dk)
- The mink (n=29) was infected and seroconverted 2-3 weeks after AMDV inoculation and AMDV antibodies persisted during the maximum experimental period of 24 weeks. (forskningsdatabasen.dk)
- This highlights the risk of transmitting AMDV between infected farms.PCR was successfully used to detect viral DNA in organs 8, 16 and 24 weeks after AMDV inoculation with only minor differences between these weeks which is of diagnostic interest.This AMDV challenge model was also used to mimic natural infection of susceptible sapphire mink. (forskningsdatabasen.dk)
- Four of 6 sapphire mink were infected indirectly via the AMDV inoculated wild type mink whereas the other 2 sapphire mink remained uninfected. (forskningsdatabasen.dk)
- [email protected]# Aleutian mink disease virus (AMDV) causes major economic losses in fur-bearing animal production . (bvsalud.org)
- The combined study of phylogenetic results and epidemiological information of each farm suggests that most of the AMDV outbreaks since 2012 had been produced by within- farm reservoirs , while a few of them may have been due to the introduction of the virus through international trade. (bvsalud.org)
- [email protected]#The combination of phylogenetic inference , together with epidemiological data, helps assess the possible origin of AMDV infections in mink farms and improving the control and prevention of this disease . (bvsalud.org)
- Aleutian mink disease virus (AMDV) is a member of the parvoviridae family which primarily affects mink, often resulting in death. (wisconsin.edu)
- Mink plasmacytosis, caused by Aleutian Mink Disease Virus (AMDV), poses a threat to the development of the animal fur industry. (bvsalud.org)
- Neutralizing antibodies against AMDV may result in a persistent infection rather than providing protection for minks. (bvsalud.org)
- In order to eliminate mink plasmacytosis, antibody detection technology has been used globally as a dominant approach to screen for AMDV-positive minks. (bvsalud.org)
- Aleutian mink disease parvovirus (AMDV) causes a persistent infection associated with immune complex disease, hypergammaglobulinemia, and high levels of antiviral antibodies. (bvsalud.org)
- In addition, the role of cytokine IL-6 in ADE mediated disease development is discussed, to facilitate a better understanding of the pathogenesis of AMDV infection, as well as give insights into rational vaccine design approaches. (bvsalud.org)
- jvs-21-e65-s006.ppt (589K) GUID:?4FD9A02E-5253-433C-9258-7AE5FB36D581 Abstract Background Aleutian mink disease virus (AMDV) causes major economic losses in fur-bearing animal production. (idh-inhibitors.com)
- Objectives This study had the following aims: characterize the AMDV strains from most outbreaks created at Spanish farms between 2012C2019 in the molecular level, and measure the utility from the combined usage of molecular and epidemiological data to monitor the feasible routes of disease. (idh-inhibitors.com)
- The combined research of phylogenetic outcomes and epidemiological info of each plantation suggests that a lot of the AMDV outbreaks since 2012 have been made by within-farm reservoirs, while those hateful pounds may have been because of the introduction from the disease ML365 through international trade. (idh-inhibitors.com)
- 2]. The development of AD depends on the virulence of the AMDV strain and the genetics of the hosts, affecting the Aleutian genotype mink [3]. (idh-inhibitors.com)
- In contrast, most AMDV infections in non-Aleutian mink are asymptomatic and even non-persistent, even though some animals can show typical disease [4,6]. (idh-inhibitors.com)
- AMDV is a non-enveloped virus with a single-stranded DNA encoding three non-structural proteins (NS1CNS3) and two capsid proteins (VP1 and VP2) [2]. (idh-inhibitors.com)
- Concerning AMDV attacks in Spanish mink farms, because the intro of counter-inmunoelectrophoresis (CIEP) tests, the percentage of positive farms offers reduced from 100% in 1980 to around 25% in 2019. (idh-inhibitors.com)
Antibodies11
- Acute Influenza A virus outbreak in an enzootic infected sow herd: Impact on viral dynamics, genetic and antigenic variability and effect of maternally derived antibodies and vaccination. (nih.gov)
- While the parvovirus itself causes little or no harm to the ferret host, the large number of antibodies produced in response to the presence of the virus results in a systemic vasculitis, resulting in eventual renal failure, bone marrow suppression and death. (wikipedia.org)
- Through the virus elicits a strong immune response from the ferret, the antibodies produced in response, don't neutralize the virus. (pethealthandcare.com)
- At times these antibodies, which are produced in huge amounts, form complexes, which get deposited in the tissues and lead to inflammation, which eventually aggravates the disease. (pethealthandcare.com)
- However, as for other common viral infections such as by the human immunodeficiency virus (HIV), there is a period of time until the appearance of antibodies after infection, or the so-called window period in which a virus is unidentifiable by existing testing methods. (wipo.int)
- The tests only show the presence of antibodies to ADV, which indicates only exposure to the disease. (ferretclub.com)
- Selected sera originating in women from case-control study carried out in Spain and Colombia found negative and positive for HPV16, 18, 31, 33 and 35 DNA were tested in ELISA for the presence of IgG antibodies to purified virus-like particles (VLP). (usda.gov)
- For new targets we consult with leading experts to accelerate development of antibodies that will propel state-of-the-art research in cellular health and disease. (abgent.com)
- After the virus enters the host, IBDV causes acute lytic infections and high titers of anti-IBDV antibodies [5, 14]. (thefreedictionary.com)
- Comparison between the counter immunoelectrophoresis test and mouse neutralization test for the detection of antibodies against rabies virus in dog sera. (ukrbiochemjournal.org)
- Although melatonin administration raises serum levels of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma), the mortality observed in neutralization experiments with the corresponding anticytokine antibodies, suggests that neither TNF-alpha nor IFN-gamma are essential for the protective effect of melatonin on murine VEE virus infection. (eattheapple.com)
Genome16
- Nearly complete viral genome sequencing and phylogenetic analysis confirmed the presence of a new parvovirus distinct from known human and animal parvoviruses and of two related TTV-like viruses highly divergent from both the TTV and TTV-like minivirus groups. (asm.org)
- Parvoviruses are linear, non-segmented single-stranded DNA viruses , with an average genome size of 5000 nucleotides. (wikipedia.org)
- JX051319 Achimota virus 1, complete genome. (dpvweb.net)
- JX051320 Achimota virus 2, complete genome. (dpvweb.net)
- AB051848 Aconitum latent virus genomic RNA, complete genome, isolate:D. (dpvweb.net)
- JN427015 Actinidia virus B isolate TP7-93B, complete genome. (dpvweb.net)
- The genome of Rabies virus, Borna disease virus and Ebola virus code for the P phosphoprotein and VP35 that can block the antiviral response induced by IFN [ 8 , 9 , 10 ]. (intechopen.com)
- Due to the problems caused by the uncertainty in alignment, existing tools for phylogenetic analysis based on multiple alignment could not be directly applied to the whole-genome comparison and phylogenomic studies of viruses. (biomedcentral.com)
- In this paper, the DL method is used to analyze the whole-proteome phylogeny of 124 large dsDNA viruses and 30 parvoviruses, two data sets with large difference in genome size. (biomedcentral.com)
- In comparison, some alignment-free methods such as the CV Tree method can be used for recovering the phylogeny of large dsDNA viruses, but they are not suitable for resolving the phylogeny of parvoviruses with a much smaller genome size. (biomedcentral.com)
- The present study represents another effort of applying an alignment-free method in analysing complete genome data to elucidate the phylogeny of two virus groups of different genome size, the large dsDNA viruses and parvoviruses. (biomedcentral.com)
- The genome sizes of dsDNA viruses are usually larger than 10 kb except those in the families Polyomaviridae (5 kb) and Papillomaviridae (7-8 kb). (biomedcentral.com)
- On the other hand, the genome sizes of ssDNA viruses are smaller than 10 kb. (biomedcentral.com)
- The genome of varicella-zoster virus (VZV), encodes at least six glycoproteins and they elicit the formation of complement-independent, complement-dependent, and non-neutralizing antibody responses. (usda.gov)
- The sequence of 91.6% (4397 bp) of the genome of one Aleutian mink disease virus from Cape Breton (NS-CB) was determined. (dal.ca)
- In the last years, interest has shifted toward mendelian genetics in mitochondrial disease, not only because the majority of the OXPHOS system subunits are encoded by the nuclear genome, but also because a large number of yet unknown nuclear proteins, such as regulatory proteins and assembly factors, are likely involved in its biogenesis and function. (statescale.ga)
Infection in mink1
- A lethal infection in mink, the Aleutian disease virus lies dormant in ferrets until stress or injury allows it to surface. (wikipedia.org)
Strains9
- Mink in the wild carry viruses with high intra-host diversity and are occasionally even co-infected by two different strains, suggesting that free-ranging mink tolerate chronic infections for extended periods of time. (microbiologyresearch.org)
- The goal of the ICTVdB is to describe all viruses of animals (vertebrates, invertebrates, protozoa), plants (higher plants and algae), bacteria, fungi, and archaea from the family level down to strains and isolates. (virology.net)
- The standardised character list for the ICTVdB should conform with the ICTV descriptions of virus families and genera, but should be extensible to allow the incorporation of detailed information that is required to differentiate between strains and isolates. (virology.net)
- these strains are designated adenoassociated viruses (AAV). (britannica.com)
- When different strains of Aleutian disease virus. (molecularstation.com)
- There are different strains of this disease which have been documented. (wikipedia.org)
- Since there are different strains of ADV, it is believed that each strain may differ in the severity of the disease they cause. (pethealthandcare.com)
- Virulent strains produce high mortality rates in Aleutian mink. (idh-inhibitors.com)
- It has also been demonstrated that melatonin protects some strains of mink against Aleutian disease, and prevents the reduction of B- and T-cells as well as Th1 cytokine secretion in mice infected with leukemia retrovirus. (eattheapple.com)
Ferrets18
- Aleutian disease (AD) is known to produce clinical signs in mink and ferrets only ( 2 , 3 ), although other mammals have reportedly been antibody positive. (cdc.gov)
- Aleutian disease, also known as mink plasmacytosis, is a disease which causes spontaneous abortion and death in minks and ferrets. (wikipedia.org)
- The virus has been found as a natural infection in the Mustelidae family within mink, ferrets, otters, polecats, stone and pine martens and within other carnivores such as skunks, genets, foxes and raccoons. (wikipedia.org)
- The disease spread from minks to ferrets, as the two were raised on the same farms. (wikipedia.org)
- Prevention is best accomplished by stopping the spread of ADV. Any new ferret, or those which have been confirmed as serum positive for the virus should be perpetually isolated from other ferrets. (wikipedia.org)
- Aleutian Disease in ferrets has become an increasing problem, affecting overall ferret health. (pethealthandcare.com)
- The Aleutian Disease Virus in ferrets (ADV) is a type of parvovirus, which gets its name from a strain of minks, as the virus was first detected in them. (pethealthandcare.com)
- The Aleutian Disease Virus in ferrets can survive in the environment, for a long period of time. (pethealthandcare.com)
- Because this disease is fairly common, ferrets can suffer from it for a while, before showing any symptoms. (pethealthandcare.com)
- Lawsonia intracellularis can cause a proliferative bowel disease, especially in younger ferrets. (merckvetmanual.com)
- Ferrets are susceptible to canine distemper virus . (merckvetmanual.com)
- Two coronaviruses cause disease in ferrets. (merckvetmanual.com)
- This disease is highly transmissible and is often brought into a group of ferrets by an asymptomatic juvenile animal. (merckvetmanual.com)
- The disease is most severe in older ferrets, which may take months to fully recover. (merckvetmanual.com)
- Most ferrets with active ADV die of liver or kidney failure at the end of the disease. (ferretclub.com)
- The Pennsylvania Ferret Club & Shelter believes that until more is known about this disease, the only responsible thing that we can do when inviting hundreds of ferret owners and their ferrets to our events is to require that all ferrets in attendance have been tested for this disease. (ferretclub.com)
- In fact, studies have shown that only a small percentage of ferrets that have tested positive for ADV will actually become clinically sick from the disease. (ferretclub.com)
- Ferrets with secondary renal cysts associated with other developmental anomalies, mesangial glomerulopathy, or end-stage kidney disease had hyperphosphatemia and elevated BUN in comparison with those with primary cystic disease and elevated BUN compared with those without renal lesions. (wordpress.com)
Parvoviruses13
- Other viruses that can infect without helper viruses are called as autonomous parvoviruses. (wikipedia.org)
- Parvoviruses are among the smallest viruses (hence the name, from Latin parvus meaning small ) and are 18-28 nm in diameter. (wikipedia.org)
- Parvoviruses can cause disease in some animals , including starfish and humans. (wikipedia.org)
- Parvoviruses do not have envelopes and are thus considered "naked" viruses. (wikipedia.org)
- Autonomous Parvoviruses do not require a helper virus like dependoviruses. (wikipedia.org)
- Parvoviruses have small nonenveloped virions (virus particles), and the icosahedral capsid (the protein shell surrounding the viral nucleic acids ) is made up of 32 capsomeres (capsid subunits) measuring 18-26 nm (1 nm = 10 −9 metre) in diameter. (britannica.com)
- Autonomous parvoviruses are small nonenveloped viruses that have oncolytic capabilities and have been exploited as a nanotool in medicine. (pubmedcentralcanada.ca)
- The trees from our analyses are in good agreement to the latest classification of large dsDNA viruses and parvoviruses by the International Committee on Taxonomy of Viruses (ICTV). (biomedcentral.com)
- The present method provides a new way for recovering the phylogeny of large dsDNA viruses and parvoviruses, and also some insights on the affiliation of a number of unclassified viruses. (biomedcentral.com)
- Parvoviruses are interesting viruses, mostly because they are so small and dependent on the cell they infect. (futurelearn.com)
- The parvoviruses are dependent on help from host cells or other viruses to replicate. (medigoo.com)
- The autonomous parvoviruses propagate in actively dividing cells, whereas the adeno-associated viruses grow in tissue cultures infected with adenoviruses and herpesviruses. (medigoo.com)
- The parvoviruses known to infect humans include B19 parvovirus in the genus Erythrovirus , adeno-associated viruses (AAVs) in the genus Dependovirus , human bocavirus (HBoV) in the genus Bocavirus , and PARV4 and PARV5, not yet placed into a genus. (asmscience.org)
Mustela3
- The American Mink (mustela vision) is a member of the family of animals known as mustelids. (wildliferesponse.org)
- Owing to the rapid decline of the European mink ( Mustela lutreola ) in France, a national conservation action plan has been initiated, in which scientific research to improve understanding of the causes of the decline is one of the primary objectives. (bioone.org)
- Development of microsatellite markers in the American mink (Mustela vison). (dal.ca)
Neovison2
- During the spring of 2015 till early winter 2015, 15 adult and eight juvenile mink ( Neovison vison ) carcasses, Nos. (biomedcentral.com)
- Mink ( Neovison vison ) is one of the major fur animals and its health problems have become an important issue for the fur industry. (biomedcentral.com)
Viral18
- Viraemia and faecal excretion of viral DNA was detected in the mink (n=29) at various and intermittent time intervals. (forskningsdatabasen.dk)
- Excretion of viral DNA in oro-nasal swabs was detected for 1-8 weeks in 21 mink. (forskningsdatabasen.dk)
- Persistent viral shedding during asymptomatic Aleutian mink disease parvoviral infection in a ferret. (harvard.edu)
- A sequence-independent PCR amplification method was used to identify viral nucleic acids in the plasma samples of 25 individuals presenting with symptoms of acute viral infection following high-risk behavior for human immunodeficiency virus type 1 transmission. (asm.org)
- The detection of two previously undescribed viral species in a small group of individuals presenting acute viral syndrome with unknown etiology indicates that a rich yield of new human viruses may be readily identifiable using simple methods of sequence-independent nucleic acid amplification and limited sequencing. (asm.org)
- The ability to perform amino acid-based similarity searches using the translated products of sequenced amplification products therefore allows the identification of viral sequences more divergent from already known viruses than do methods relying on nucleic acid hybridization. (asm.org)
- DNase-SISPA was used here to determine whether known and previously uncharacterized viruses could be identified in the plasma samples of 25 patients suffering from acute viral infection syndrome. (asm.org)
- The left-end origin of minute virus of mice (MVM), oriL, contains binding sites for the viral initiator nickase, NS1, and parvovirus initiation factor (PIF), a member of the emerging KDWK family of transcription factors. (asm.org)
- As in other RCR systems, minute virus of mice (MVM) encodes, in NS1, a site-specific nickase, which recognizes disparate origin sequences present in the two viral termini and is able to nick and resolve these concatemers into unit-length molecules ( 12 , 13 , 15 ). (asm.org)
- Among DNA viruses, B19V has a unique feature in the processing of its precursor mRNA (pre-mRNA) in that all the viral mRNAs are alternatively processed from a single pre-mRNA. (labome.ru)
- Therefore, there is an urgent need to develop effective, non-toxic, and environmentally friendly antiviral drugs to control viral infections in mink. (biomedcentral.com)
- Sequence and phylogenetic analysis revealed that viral sequences showing a close relationship with Dabieshan tick virus, Aleutian mink disease virus, adeno-associated virus, Gokushovirus, avian gyrovirus 2 were present in the virome of these ticks. (bvsalud.org)
- The construction of the PVX vector required the new plasmid to be amplified in E. coli before inoculating plants, which would be necessary to construct a plant virus vectored viral genes for a vaccine for these two viruses. (biomedcentral.com)
- When the eukaryotic expression vectors are derived from viruses, certain viral sequences might be recognized as promoter elements. (biomedcentral.com)
- Defective particles are naturally occurring virus mutants that lack one or more genes required for viral replication. (storysteel.gq)
- In conclusion, the immunomodulatory, antioxidant, and neuroprotective effects of melatonin suggest that this indole must be considered as an additional therapeutic alternative to fight viral diseases. (eattheapple.com)
- Methods for treating cancer, viral diseases, respiratory. (google.es)
- Methods for treating cancer, viral diseases, respiratory and immune regulatory diseases, inflammations, infections and infestations by administering an acetylated mannan derivative, such as acemannan derived from aloe, are described. (google.es)
Infects4
- The virus B19 was discovered in blood serum and infects red blood cell precursors. (wikipedia.org)
- Likewise, in the mink kits that survive, it infects the alveolar cells and ultimately causes respiratory distress, possibly leading to death. (wikipedia.org)
- Aleutian mink disease parvovirus (ADV) infects macrophages but infection is restricted. (usda.gov)
- The virus infects and lyses erythroid precursor cells leading to a drop in reticulocyte count and transient anemia. (medigoo.com)
Humans8
- The heart of such a universal virus database is a standardised character list capable to describe unambiguously all viruses of humans, animals, plants, invertebrates, protozoa, bacteria and fungi. (virology.net)
- The identification of previously uncharacterized viruses infecting humans and animals remains a constant task. (asm.org)
- Finally, Erythroparvovirus contains an important pathogen of humans, parvovirus B19, which produces the so-called "fifth disease" in children, a type of erythema. (futurelearn.com)
- The « missing link » between bats and humans could well be the mink - though the raccoon dog is also suspected. (reporterre.net)
- Freuling added that transmission without making the host sick is typical of a well-adapted virus, which may confirm the hypothesis that this species could be the « missing link » between bats and humans. (reporterre.net)
- BACKGROUND: Ticks (class Arachnida, subclass Acari) are vectors of transmitting a broad range of pathogenic microorganisms, protozoa, and viruses affecting humans and animals. (bvsalud.org)
- Viruses in two subfamilies, the Parvovirinae and Densovirinae , are distinguished primarily by their respective ability to infect vertebrates (including humans) versus invertebrates. (ictvonline.org)
- These viruses include feline panleukopenia virus, canine parvovirus, Aleutian mink disease virus, and porcine parvovirus, adeno-associated viruses, also members of the Parvoviridae family, appear to infect humans without causing clinical manifestations and have been used as vectors for gene transduction and gene therapy. (medigoo.com)
Proteins6
- Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. (edu.au)
- They are utilized to investigate genes in cell cultures of the proteins which are encoded by those genes via mass production method or manipulated as probable vectors to examine genes in the cells of patients for diagnosis and treatment of several genetic diseases and cancers. (wikipedia.org)
- These processes are associated with the production of antigenic proteins that make the virus vulnerable to immune control mechanisms 'warning' the host of the presence of an invader [ 1 ]. (intechopen.com)
- Viruses encode homologs of complement regulatory proteins that are secreted and block complement activation and neutralization of virus particles. (intechopen.com)
- All IFNs identified in vertebrates are secreted proteins, with IFN-α being secreted from virus-infected white blood cells. (biomedcentral.com)
- The diseases associated with M proteins are listed in Table 104-1. (wordpress.com)
Infections7
- How dysregulation of the immune system results in immunodeficiencies, autoimmunity, inflammation, allergy, chronic infections, and lymphoproliferative diseases and what strategies might be valuable for therapeutic or vaccine development related to these conditions as well as cancer are important topics of interest, as is the behavior of the meta-organism. (nih.gov)
- Some infections do not result in visible infection, while some manifest with visible effects, such as fifth disease (erythema infectiosum), which can give children a 'slapped-cheek' appearance. (wikipedia.org)
- These bacteria are also common in several other infectious conditions in mink, such as urinary tract infections, pneumonia, and pleuritis. (biomedcentral.com)
- Chronic Infectious Neuropathie Agents (China) and Other Slow Virus Infections. (annals.org)
- Reviews of infections with other "slow" viruses (Aleutian mink disease virus and lymphocytic choriomeningitis virus) emphasize a potential importance of immune and autoimmune reactions in the pathogenesis of some chronic nervous system disorders. (annals.org)
- Since EHV-1 is a DNA virus, this type of PCR is rarely used to detect lytic infections but more likely for detecting and quantifying latent EHV-1 in tissues and whole blood (Borchers et al. (thefreedictionary.com)
- At metaphylactic vaccination because of latently / acute distemper virus infections animal losses are possible. (drugs.com)
Adeno-assoc1
- Three genera in the subfamily Parvoviridae are recognized: Parvovirus, Erythrovirus, and Dependovirus, which includes the adeno-associated virus. (medigoo.com)
Lesions2
- Lesions can also be found within the pelt depending on the severity of the disease. (wikipedia.org)
- This study presents the isolation of Arcanobacterium phocae from mink with severe skin lesions and other pathological conditions, and from wild seals and otters. (biomedcentral.com)
Parvovirinae5
- the Parvovirinae (vertebrate viruses) and the Densovirinae (invertebrate viruses). (wikipedia.org)
- Different examples can be given for the subfamily Parvovirinae but the most common is Dependovirus , which only work with a helper virus such as adenovirus. (wikipedia.org)
- Type species of the Parvovirinae include minute virus of mice, human parvovirus, and Aleutian mink disease virus. (britannica.com)
- Amdoparvovirus is a genus of viruses, in the family Parvoviridae, in the subfamily Parvovirinae. (wikipedia.org)
- Group: ssDNA Order: Unassigned Family: Parvoviridae Sub-Family: Parvovirinae Genus: Amdoparvovirus Carnivore amdoparvovirus 1 Carnivore amdoparvovirus 2 Carnivore amdoparvovirus 3 Carnivore amdoparvovirus 4 Viruses in the genus Amdoparvovirus have non-enveloped protein particles with T=1 icosahedral symmetry. (wikipedia.org)
Parvoviridae4
- Parvovirus is the common name applied to all the viruses in the Parvoviridae taxonomic family. (wikipedia.org)
- The remainder of this article discusses the disease-causing Parvoviridae . (wikipedia.org)
- Parvovirus , any virus belonging to the family Parvoviridae. (britannica.com)
- Members of family Parvoviridae are small, resilient, non-enveloped viruses with linear, single-stranded DNA genomes of 4-6 kb. (ictvonline.org)
Molecular5
- Nucleotide sequence of the 5'-terminal palindrome of Aleutian mink disease parvovirus and construction of an infectious molecular clone. (microbiologyresearch.org)
- The Laboratory of Immune System Biology (LISB) is focused on the basic genetics, molecular biology, and cell biology of the immune system, as well as on human disease informed by these more basic studies. (nih.gov)
- By the same token, the advent of molecular biology brought so many new aspects and data important for the concise description of a virus, that it is difficult to pick only the most basic characteristics without loosing specificity important during the identification process. (virology.net)
- To analyze the molecular mechanisms of cross-host transmission of the Aleutian mink disease vi rus (ADV), the hypervariable region fragment of the VP2 gene of the ADV in Jilin Province (China) was amplified. (bvsalud.org)
- NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease. (furosemideforsale.site)
Mustelids1
- The American mink shares the common characteristic of all mustelids: anal musk glands that are used for territory marking and defense. (wildliferesponse.org)
Human parvovirus1
- Aleutian mink disease virus, 25 feline panleukopenia virus (FPLV), 26 human parvovirus B19, 27 - 29 parvovirus H-1, 30 and rat parvovirus 31 have been reported to induce apoptotic cell death while bovine parvovirus infected cells are necrotic. (pubmedcentralcanada.ca)
Immune9
- Use of animals in biomedical research is necessary to expand our ability to curtail infectious diseases, characterize new diseases, combat bioterrorism, and discover new ways to augment or harness the body's immune system. (nih.gov)
- Laboratory of Immunoregulation (LIR) studies the regulation of the human immune system in health and disease, with emphasis on the immunopathogenic mechanisms of HIV infection and disease progression. (nih.gov)
- Diseases associated with this genus include progressive disorder of immune system. (wikipedia.org)
- Therefore, the symptoms are actually caused by the ferret's immune response to the virus. (pethealthandcare.com)
- While Aleutian disease does not really cause any direct harm, it depresses the ferret's immune system in such a way, that the animal becomes susceptible to a number of other diseases. (pethealthandcare.com)
- During the period of coexistence with their hosts, viruses have learned how to manipulate host immune control mechanism. (intechopen.com)
- The present review will highlight the different complex mechanisms associated with the host immune evasion by the viruses with special reference to the Classical Swine Fever Virus. (intechopen.com)
- There are certain cellular components which are manipulated by viruses to evade the innate immune response. (intechopen.com)
- In a lytic infection the virus is exposed to components of the immune response that have the potential to clear the virus from the host. (thefreedictionary.com)
Farms5
- This is most commonly due to escapees within farms, who when free are hybridizing with wild mink. (wikipedia.org)
- In 2015, A. phocae was isolated for the first time in Denmark from outbreaks of dermatitis in mink farms. (biomedcentral.com)
- 1-23, (Table 1 ) originating from 12 mink farms (Fig. 1 ) were submitted to the National Veterinary Institute, Technical University of Denmark for laboratory examination. (biomedcentral.com)
- It seems increasingly plausible that Covid-19 originated in fur farms, especially mink, as our investigation shows. (reporterre.net)
- This is similar to mink as we saw in Mink farms in Denmark and the Netherlands . (reporterre.net)
Ferret5
- The diagnosis of this disease can be a little difficult and usually requires various tests to be performed on the ferret. (pethealthandcare.com)
- It should be noted that neither of these tests can predict whether or not your ferret will actually become sick with ADV or if it will even spread the disease. (ferretclub.com)
- The ferret is a small sleek fur-bearing mammal that belongs to the same Family as the otter, weasel, wolverine, and mink. (allferrets.org)
- Unlike its cousins the otter, weasel, and mink, the pet ferret is not a wild animal. (allferrets.org)
- Cystic Renal Disease in the Domestic Ferret. (wordpress.com)
Skunks1
- Positive PCR or CIEP samples were detected in 56 of 60 (93.3%) American mink, 43 of 61 (70.5%) short-tailed weasels, 2 of 8 (25.0%) striped skunks, 2 of 11 (18.2%) North American river otters, 9 of 85 (10.6%) raccoons, and 2 of 20 (10.0%) bobcats. (biomedcentral.com)
Replication6
- Their limited coding capacity means that these viruses must rely predominantly upon host cell replication factors, augmented and orchestrated by the virus-encoded pleiotropic initiator protein NS1 ( 3 , 10 , 26 , 29 , 30 ). (asm.org)
- Nevertheless, to exist as a species, virus replication and transfer to a new host are essential. (intechopen.com)
- By using strand-specific in situ hybridization and immunohistochemistry, evidence for replication of the Aleutian mink disease parvovirus was observed in cells resembling macrophages and cells resembling follicular dendritic cells at 10 days after infection but only in macrophages at 60 days. (elsevier.com)
- Bloom, M. E. / Replication of Aleutian mink disease parvorivus in lymphoid tissues of adult mink : Involvement of follicular dendritic cells and macrophages . (elsevier.com)
- Dependovirus are the smallest parvovirus, and require or depend on the presence of other viruses for replication. (futurelearn.com)
- A steady replication of vaccine virus is necessary for that. (drugs.com)
Free-rang1
- Samples were placed in plastic bags, identified and stored in house freezers (−15°C) before delivery to the laboratory on ice for long-term storage at −80°C. In addition, carcasses of four free-ranging mink from the province of New Brunswick were tested. (biomedcentral.com)
Sequence13
- EF546802 Abaca bunchy top virus isolate Q1108 segment DNA-N, complete sequence. (dpvweb.net)
- KC430935 Abutilon golden mosaic Yucatan virus isolate Conkal-2007 segment A, complete sequence. (dpvweb.net)
- HM585445 Abutilon mosaic Bolivia virus segment DNA-A, complete sequence. (dpvweb.net)
- JF694479 Abutilon mosaic Brazil virus isolate BgV06B.1.C77 segment DNA-B, complete sequence. (dpvweb.net)
- JF694480 Abutilon mosaic Brazil virus isolate BgV01A.1.C21 segment DNA-A, complete sequence. (dpvweb.net)
- JF694481 Abutilon mosaic Brazil virus isolate BgV01A.1.C67 segment DNA-A, complete sequence. (dpvweb.net)
- JF694483 Abutilon mosaic Brazil virus isolate BgV01B.1.C35 segment DNA-B, complete sequence. (dpvweb.net)
- HQ588899 Abutilon mosaic virus strain IN-Udg-JIE1-2010 segment DNA-A, complete sequence. (dpvweb.net)
- HQ588901 Abutilon mosaic virus strain IN-Udg-JIX12-2010 segment DNA-A, complete sequence. (dpvweb.net)
- EU559678 Abutilon yellow mosaic virus genomic sequence. (dpvweb.net)
- The vast sequence divergence among different virus groups has presented a great challenge to alignment-based analysis of virus phylogeny. (biomedcentral.com)
- The homologies of the 13 mink IFN-α genes were 93.6-99.3% and 88.8-98.4% at the nucleotide and amino acid sequence levels, respectively. (biomedcentral.com)
- RESULTS: From the 300 ticks, 1,218,388 high-quality reads were generated, of which 5643 (0.463%) reads showed significant sequence identity to known viruses. (bvsalud.org)
Susceptible2
- The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are particularly susceptible. (harvard.edu)
- It was assumed that the disease was a result of poor genetics, but it was later found that minks of all coat colors were susceptible to the disease - but tend to have a lower mortality compared with Aleutian Mink. (wikipedia.org)
Mechanisms1
- Mechanisms allowing persistance of agents for long periods before producing disease are discussed. (annals.org)
Detection1
- Reports on the detection of viruses such as the isolation of an avian influenza virus in Norway for the first time, and the second case in Finland of European bat lyssavirus type2 in a Daubenton's bat. (biomedcentral.com)
Chronic disease1
- chronic disease reflects a restricted or abortive infection of specific cell types ( 1 ). (cdc.gov)
Mortality3
- In four Danish mink ranches acute interstitial pneumonitis caused excessive mortality among kits within the first 2 1/2 months after parturition. (molecularstation.com)
- Melatonin also postpones the onset of the disease produced by Semliki Forest virus inoculation and reduces the mortality of West Nile virus-infected mice stressed by either isolation or dexamethasone injection. (eattheapple.com)
- In VEE-infected mice, melatonin postpones the onset of the disease and death for several days and reduces the mortality rate. (eattheapple.com)
Acute3
- In mink kits, AD causes an acute cytopathic infection of alveolar cells, which leads to respiratory distress and death ( 8 ). (cdc.gov)
- Specimens for analysis were plasma samples from subjects screened for acute human immunodeficiency virus (HIV) infection in the University of California, San Francisco (UCSF) Options Project but found to be HIV negative. (asm.org)
- Acute interstitial pneumonitis caused by Aleutian disease virus in mink kits. (molecularstation.com)
Gene11
- The disease was so named because it was first found in mink with the Aleutian coat color gene, a gun-metal grey pelt. (wikipedia.org)
- FJ787433 Abaca bunchy top virus isolate Laguna coat protein gene, complete cds. (dpvweb.net)
- AY422070 Abutilon yellows virus coat protein gene and partial coat protein, complete cds. (dpvweb.net)
- EU184018 Acalypha yellow mosaic virus - [Barrackpore] coat protein (AV1) gene, complete cds. (dpvweb.net)
- JN807766 Acalypha yellow mosaic virus-[Croton] isolate Croton coat protein (AV1) gene, complete cds. (dpvweb.net)
- Viruses have great potential as nanotools in medicine for gene transfer, targeted gene delivery, and oncolytic cancer virotherapy. (pubmedcentralcanada.ca)
- The phylogeny based on single genes or gene families contains ambiguity because horizontal gene transfer (HGT), along with gene duplication and gene capture from hosts, appear to be frequent in large DNA viruses [ 7 - 10 ]. (biomedcentral.com)
- The nucleotide sequences of the SH gene of 45 new mumps virus isolates derived from different parts of Europe, Canada and USA were determined. (usda.gov)
- Identification of a disease causing gene rarely leads to the invention of a novel therapy. (furosemideforsale.site)
- It was previously reported that there was a cryptic promoter associated with a toxic gene in potato virus Y (PVY) that interrupted cloning work in E. coli [ 8 ]. (biomedcentral.com)
- Here, we examine the genetic structure and relative expression of MeE3L (native and gene-edited mutant), and determine how MeE3L affects geminivirus South African cassava mosaic virus (SACMV) DNA accumulation. (researchsquare.com)
Species7
- Solid signs and open signs represent Aleutian mink disease virus infected and non-infected species, respectively. (biomedcentral.com)
- The database is still in its infancy and only the morphological and genomic aspects have been recorded for of all virus families and genera including their type species. (virology.net)
- There are currently four species in this genus, including the type species Carnivore amdoparvovirus 1 (Aleutian mink disease virus). (wikipedia.org)
- In order to investigate the possible role of Aleutian disease parvovirus (ADV) in decline of the species, a serologic survey was conducted from March 1996 to March 2002 in 420 free-ranging individuals of six species of small carnivores distributed in eight départements of southwestern France. (bioone.org)
- 0:14 Skip to 0 minutes and 14 seconds In this step we are going to focus on the parvovirus, which are one of the most common causes of disease amongst pets, but also in other species. (futurelearn.com)
- By contrast, animals bred for their fur, particularly the three main species - mink, fox, and the raccoon dog - are highly sensitive to it. (reporterre.net)
- Reactive oxygen species have been implicated in the dissemination of this virus, and their deleterious effects may be diminished by melatonin. (eattheapple.com)
Immunoelectrophoresis4
- Examination of Aleutian disease virus in charge-shift crossed immunoelectrophoresis. (molecularstation.com)
- The surface properties of Aleutian disease virus were studied by charge-shift crossed immunoelectrophoresis. (molecularstation.com)
- Counter current line absorption immunoelectrophoresis is an alternative diagnostic screening test to counter current electrophoresis in Aleutian disease (AD) eradication programs. (thefreedictionary.com)
- Raj GD, Thangavelu A, Elankumaran S, Koteeswaran A. Rocket immunoelectrophoresis in the diagnosis of infectious bursal disease. (ukrbiochemjournal.org)
Causative agent1
- Japanese Patent Publication (Kohyo) 2 (1990) - 500880), it was found that hepatitis C is an infectious disease who causative agent is hepatitis C virus (HCV) that is transmitted through the blood and blood products as its main route of infection. (wipo.int)
Outbreaks1
- During school outbreaks of the virus, 10 to 60% of students may get fifth disease. (medigoo.com)
Amdoparvovirus2
- It is caused by Carnivore amdoparvovirus 1 (also known as Aleutian disease virus, ADV), a highly contagious parvovirus in the genus Amdoparvovirus. (wikipedia.org)
- Aleutian disease virus-like virus (Amdoparvovirus sp. (elsevier.com)
Weasel1
- Positive CIEP or PCR animals were present in all nine counties from which mink or weasel samples were collected. (biomedcentral.com)
Genomic2
- We have already mentioned in a previous activity that this genomic simplicity implies that parvovirus needs the cell to be actively dividing, even more so than other viruses. (futurelearn.com)
- If a helper virus is not present, AAV integrates into the host cell genomic DNA in a site-specific fashion. (asmscience.org)
Otters1
- Here we present a collection of articles published in Acta Veterinaria Scandinavica advancing our knowledge of wildlife research, ranging from diseases in reindeer to mountain goats to gulls to otters to moles. (biomedcentral.com)
Emerging Infectio1
- Our research focuses on emerging infectious diseases in human and animals. (helsinki.fi)
Virulent1
- The viruses responsible are commonly called virulent phages. (thefreedictionary.com)
Nucleic acid2
- Characterization of the protein and nucleic acid of Aleutian disease virus. (microbiologyresearch.org)
- Amplification products are subcloned and sequenced, and their similarities to known viruses were tested using BLASTn (for nucleic acid similarity) and tBLASTx (for protein similarity) ( 1 ). (asm.org)
Mice1
- Melatonin has been shown to prevent paralysis and death in mice infected with the encephalomyocarditis virus and to decrease viremia. (eattheapple.com)
Tissue4
- Because the viruses require actively dividing cells to replicate, the type of tissue infected varies with the age of the animal. (wikipedia.org)
- In the 1960s, it was common practice for mink ranchers to make their own distemper vaccines by homogenizing tissue from distemper-infected mink, making suspensions, and injecting all the mink on their ranch. (wikipedia.org)
- The cowpox virus (CPV) complement inhibitor, termed inflammation modulatory protein (IMP), blocks immunopathological tissue damage at the site of infection, presumably by inhibiting production of the macrophage chemo attractant factors C3a and C5a. (intechopen.com)
- With the appropriate helper virus, AAVs can replicate in a variety of tissue culture systems. (asmscience.org)
Genes3
- U51137 Abutilon mosaic virus-HW AV1 and partial coat protein, AC3 and partial coat protein, AC2 and partial coat protein, AC1 and partial coat protein, and AC4 genes and partial coat protein, complete cds. (dpvweb.net)
- U51138 Abutilon mosaic virus-HW BV1 and BC1 genes and partial coat protein, complete cds. (dpvweb.net)
- In this study, we cloned the genes for 13 IFN-α subtypes from peripheral blood lymphocytes of the mink. (biomedcentral.com)
Liver1
- Based on these findings, it is suggested that the nematode M. giraffae may not be an unusual parasite of the giraffe and that it does not necessarily cause detrimental liver disease. (labome.org)
Strain1
- Active immunization of minks with an attenuated distemper virus, strain D 84/1 as an aid in the prevention of disease due to distemper virus. (drugs.com)
Infectious disease3
- This is a growing concern within mink producers as it is the most significant infectious disease affecting farmed mink worldwide. (wikipedia.org)
- The invention also relates to methods for making such complexes and compositions comprising alpha (2) macroglobulin complexes, isolated from the serum of a mammal, wherein such compositions are used in methods for the treatment and prevention of cancer and infectious disease. (patents.com)
- The invention also relates to methods for treating and preventing cancer and infectious disease using such complexes comprising, isolated from the serum of a mammal. (patents.com)
Adult2
- This virus can unfortunately reduce fitness of wild mink especially, by disturbing both the productivity within adult females and the overall survivor rates of both juveniles and adults. (wikipedia.org)
- The objective of our study was to determine the socioecologic factors that predict readiness for self-management and transition from pediatric to adult health care services, adherence to taking medications, and health care utilization among adolescents and young adults with chronic kidney disease. (storysteel.gq)
Persistent1
- It is an opportunistic pathogen and can induce chronic, persistent gastritis and ulcer formation similar to the disease in people. (merckvetmanual.com)
Characterization1
- Characterization of Aleutian disease virus as a parvovirus. (microbiologyresearch.org)
Pathogenesis4
- Polarisation of Major Histocompatibility Complex II Host Genotype with Pathogenesis of European Brown Hare Syndrome Virus. (dtu.dk)
- The journal encourages papers providing results that have clear implications for understanding disease pathogenesis and for the development of control measures or treatments, as well as those dealing with a comparative biomedical approach, which represents a substantial improvement to animal and human health. (elsevier.com)
- Studies on the pathogenesis of Aleutian disease in mink. (geoscience.net)
- Evaluation of T and B lymphocyte function in the pathogenesis of Aleutian disease virus infection of mink. (coopsifas.com)
Particles3
- In each city associations between particles with an aerodynamic diameter of less than 10 microm (PM(10)) and black smoke and daily counts of emergency hospital admissions for asthma (0-14 and 15-64 yr), chronic obstructive pulmonary disease (COPD), and all-respiratory disease (65+ yr) controlling for environmental factors and temporal patterns were investigated. (arctichealth.org)
- Viruses can exist in two forms: extra cellular virion particles and intracellular genomes. (intechopen.com)
- 1 - 5 In addition, CPV virus-like particles have been employed in delivery of drugs. (pubmedcentralcanada.ca)
Avian1
- BACKGROUND: Avian influenza virus (AIV) subtypes H5 and H7 attracts particular attention because of the risk of their potential pathogenicity in poultry. (usda.gov)
MRNA1
- Qiu J , Cheng F , Pintel D . The abundant R2 mRNA generated by aleutian mink disease parvovirus is tricistronic, encoding NS2, VP1, and VP2. (microbiologyresearch.org)
MeSH1
- Aleutian Mink Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)