A slow progressive disease of mink caused by the ALEUTIAN MINK DISEASE VIRUS. It is characterized by poor reproduction, weight loss, autoimmunity, hypergammaglobulinemia, increased susceptibility to bacterial infections, and death from renal failure. The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are particularly susceptible.
A species of PARVOVIRUS that causes a disease in mink, mainly those homozygous for the recessive Aleutian gene which determines a desirable coat color.
Carnivores of genus Mustela of the family MUSTELIDAE. The European mink, which has white upper and lower lips, was widely trapped for commercial purposes and is classified as endangered. The American mink, lacking a white upper lip, is farmed commercially.
A family of very small DNA viruses containing a single molecule of single-stranded DNA and consisting of two subfamilies: PARVOVIRINAE and DENSOVIRINAE. They infect both vertebrates and invertebrates.
A genus of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, infecting a variety of vertebrates including humans. Parvoviruses are responsible for a number of important diseases but also can be non-pathogenic in certain hosts. The type species is MINUTE VIRUS OF MICE.
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Proteins that form the CAPSID of VIRUSES.
The outer protein protective shell of a virus, which protects the viral nucleic acid.
Deoxyribonucleic acid that makes up the genetic material of viruses.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Established cell cultures that have the potential to propagate indefinitely.
An excess of GAMMA-GLOBULINS in the serum due to chronic infections or PARAPROTEINEMIAS.
Animals considered to be wild or feral or not adapted for domestic use. It does not include wild animals in zoos for which ANIMALS, ZOO is available.
A space in which the pressure is far below atmospheric pressure so that the remaining gases do not affect processes being carried on in the space.
The most well known avian paramyxovirus in the genus AVULAVIRUS and the cause of a highly infectious pneumoencephalitis in fowl. It is also reported to cause CONJUNCTIVITIS in humans. Transmission is by droplet inhalation or ingestion of contaminated water or food.
Viruses whose taxonomic relationships have not been established.
Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.
A province of eastern Canada, one of the Maritime Provinces with NEW BRUNSWICK; PRINCE EDWARD ISLAND; and sometimes NEWFOUNDLAND AND LABRADOR. Its capital is Halifax. The territory was granted in 1621 by James I to the Scotsman Sir William Alexander and was called Nova Scotia, the Latin for New Scotland. The territory had earlier belonged to the French, under the name of Acadia. (From Webster's New Geographical Dictionary, 1988, p871 & Room, Brewer's Dictionary of Names, 1992, p384)
Immunoelectrophoresis in which immunoprecipitation occurs when antigen at the cathode is caused to migrate in an electric field through a suitable medium of diffusion against a stream of antibody migrating from the anode as a result of endosmotic flow.
Fish-eating carnivores of the family MUSTELIDAE, found on both hemispheres.
The family of omnivorous New World skunks, showing typical warning coloration of patterned black and white and able to eject a malodorous secretion when the animal is startled or in danger.
An enzyme isolated from horseradish which is able to act as an antigen. It is frequently used as a histochemical tracer for light and electron microscopy. Its antigenicity has permitted its use as a combined antigen and marker in experimental immunology.
The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.
The functions and properties of living organisms, including both the physical and chemical factors and processes, supporting life in single- or multi-cell organisms from their origin through the progression of life.
The contribution to barometric PRESSURE of gaseous substance in equilibrium with its solid or liquid phase.
Inherited myotonic disorders with early childhood onset MYOTONIA. Muscular hypertrophy is common and myotonia may impair ambulation and other movements. It is classified as Thomsen (autosomal dominant) or Becker (autosomal recessive) generalized myotonia mainly based on the inheritance pattern. Becker type is also clinically more severe. An autosomal dominant variant with milder symptoms and later onset is known as myotonia levior. Mutations in the voltage-dependent skeletal muscle chloride channel are associated with the disorders.
A plant genus of the family FAGACEAE that is a source of TANNINS. Do not confuse with Holly (ILEX).
Former state in north central Germany. Formally abolished March 1, 1947. Kingdom established 1701.
An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.
A form of inherited long QT syndrome (or LQT7) that is characterized by a triad of potassium-sensitive periodic paralysis, VENTRICULAR ECTOPIC BEATS, and abnormal features such as short stature, low-set ears, and SCOLIOSIS. It results from mutations of KCNJ2 gene which encodes a channel protein (INWARD RECTIFIER POTASSIUM CHANNELS) that regulates resting membrane potential.
The concurrent or retrospective review by practicing physicians or other health professionals of the quality and efficiency of patient care practices or services ordered or performed by other physicians or other health professionals (From The Facts On File Dictionary of Health Care Management, 1988).
A species of gram-positive, coccoid bacteria commonly isolated from clinical specimens and the human intestinal tract. Most strains are nonhemolytic.
A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
An operating division of the US Department of Health and Human Services. It is concerned with the overall planning, promoting, and administering of programs pertaining to health and medical research. Until 1995, it was an agency of the United States PUBLIC HEALTH SERVICE.
A white threadlike worm which causes elephantiasis, lymphangitis, and chyluria by interfering with the lymphatic circulation. The microfilaria are found in the circulating blood and are carried by mosquitoes.
An endopeptidase that is structurally similar to MATRIX METALLOPROTEINASE 2. It degrades GELATIN types I and V; COLLAGEN TYPE IV; and COLLAGEN TYPE V.
Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.
Databases devoted to knowledge about specific genes and gene products.
Proteases which use a metal, normally ZINC, in the catalytic mechanism. This group of enzymes is inactivated by metal CHELATORS.
The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.
Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.

Three-dimensional structure of Aleutian mink disease parvovirus: implications for disease pathogenicity. (1/70)

The three-dimensional structure of expressed VP2 capsids of Aleutian mink disease parvovirus strain G (ADVG-VP2) has been determined to 22 A resolution by cryo-electron microscopy and image reconstruction techniques. A structure-based sequence alignment of the VP2 capsid protein of canine parvovirus (CPV) provided a means to construct an atomic model of the ADVG-VP2 capsid. The ADVG-VP2 reconstruction reveals a capsid structure with a mean external radius of 128 A and several surface features similar to those found in human parvovirus B19 (B19), CPV, feline panleukopenia virus (FPV), and minute virus of mice (MVM). Dimple-like depressions occur at the icosahedral twofold axes, canyon-like regions encircle the fivefold axes, and spike-like protrusions decorate the threefold axes. These spikes are not present in B19, and they are more prominent in ADV compared to the other parvoviruses owing to the presence of loop insertions which create mounds near the threefold axes. Cylindrical channels along the fivefold axes of CPV, FPV, and MVM, which are surrounded by five symmetry-related beta-ribbons, are closed in ADVG-VP2 and B19. Immunoreactive peptides made from segments of the ADVG-VP2 capsid protein map to residues in the mound structures. In vitro tissue tropism and in vivo pathogenic properties of ADV map to residues at the threefold axes and to the wall of the dimples.  (+info)

Replication of Aleutian mink disease parvovirus in vivo is influenced by residues in the VP2 protein. (2/70)

Aleutian mink disease parvovirus (ADV) is the etiological agent of Aleutian disease of mink. Several ADV isolates have been identified which vary in the severity of the disease they elicit. The isolate ADV-Utah replicates to high levels in mink, causing severe Aleutian disease that results in death within 6 to 8 weeks, but does not replicate in Crandell feline kidney (CrFK) cells. In contrast, ADV-G replicates in CrFK cells but does not replicate in mink. The ability of the virus to replicate in vivo is determined by virally encoded determinants contained within a defined region of the VP2 gene (M. E. Bloom, J. M. Fox, B. D. Berry, K. L. Oie, and J. B. Wolfinbarger. Virology 251:288-296, 1998). Within this region, ADV-G and ADV-Utah differ at only five amino acid residues. To determine which of these five amino acid residues comprise the in vivo replication determinant, site-directed mutagenesis was performed to individually convert the amino acid residues of ADV-G to those of ADV-Utah. A virus in which the ADV-G VP2 residue at 534, histidine (H), was converted to an aspartic acid (D) of ADV-Utah replicated in CrFK cells as efficiently as ADV-G. H534D also replicated in mink, causing transient viremia at 30 days postinfection and a strong antibody response. Animals infected with this virus developed diffuse hepatocellular microvesicular steatosis, an abnormal accumulation of intracellular fat, but did not develop classical Aleutian disease. Thus, the substitution of an aspartic acid at residue 534 for a histidine allowed replication of ADV-G in mink, but the ability to replicate was not sufficient to cause classical Aleutian disease.  (+info)

Unusual, high genetic diversity of Aleutian mink disease virus. (3/70)

The genetic diversity of Aleutian mink disease virus (AMDV) was examined. Sequences obtained from 35 clinical samples were compared with five published sequences. An unusual, high genetic variability was revealed. Three phylogenetic subgroups of AMDV were identified, and the presence of more than one genotype at some farms was detected.  (+info)

Replication of Aleutian mink disease parvovirus in mink lymph node histocultures. (4/70)

Aleutian mink disease parvovirus (ADV), causes an immune disorder with a persistent infection of lymphoid organs in adult mink. We studied replication of ADV in gel-supported histocultures prepared from adult mink mesenteric lymph node (MLN). Evidence of virus replication in the histocultures was first observed by indirect immunofluorescence 72 h after incubation with virus. Cells resembling lymphocytes and macrophages contained both ADV capsid (VP2) and nonstructural (NS1 and NS2) proteins, and were present in a distribution suggestive of infected cells within germinal centres. ADV replicative form and encapsidated virion DNA were also detected in infected histocultures at time-points after 72 h. In addition, we were able to passage ADV-Utah to a new round of histocultures. These results suggested that the infected cells were actual target cells for ADV replication and that productive ADV-Utah replication, complete with the generation of virus, was occurring in the histocultures. The mink MLN histocultures provide a system to study the replication and molecular pathogenesis of ADV in target tissues.  (+info)

Nonsuppurative meningoencephalitis associated with Aleutian mink disease parvovirus infection in ranch mink. (5/70)

Severe nonsuppurative meningoencephalitis associated with Aleutian mink disease parvovirus (ADV) infection was observed in adult ranch mink. Brain lesions included severe, locally extensive to coalescing lymphoplasmacytic meningoencephalitis with accompanying gliosis, satellitosis, and mild extension of inflammation into the leptomeninges. ADV was identified in mesenteric lymph node, spleen, brain, and liver of affected mink by polymerase chain reaction techniques. Sequences of the ADV isolate (TH5) revealed 2 unique residues in the region of the viral genome that determines pathogenicity. These findings suggest that certain strains of ADV may preferentially cause disease in the nervous system. ADV infection should be considered in the differential diagnosis of neurologic disorders in mink.  (+info)

Spontaneous Aleutian disease in a ferret. (6/70)

A 3-year-old female ferret died five days after admission to a veterinary clinic for treatment of acute dyspnea and posterior paresis. Blood chemistry showed no hypergammaglobulinemia. Histopathological examination revealed mild to severe inflammatory infiltrates, composed mostly of plasma cells, in multiple organs. Lesions were especially severe in the kidneys, where focal segmental membranous glomerulopathy was also present. In the liver, in addition to lymphocytic and plasmacytic infiltration in periportal areas, dilatation and proliferation of the bile ducts were seen. On analysis of PCR products, using primers directed against the gene encoding Aleutian disease (AD) viral capsid and formalin-fixed kidney samples, we detected a single band of about 400 bp, specific to the AD virus.  (+info)

Poly IC therapy in aleutian disease of mink. (7/70)

Twenty-four virgin female aleutian mink were infected with aleutian disease agent and after 24 hours, 12 of these were treated with a course of polyinosinic acid-polycytidilic acid (Poly IC) injections. After six weeks the gammaglobulin level was significantly lower in the treated group but at 12 weeks this difference was no longer present. Four of the treated mink had normal target organ histology when killed at 20 weeks. The untreated group all showed moderate to marked changes but this difference was not statistically significant. There was a marked increase in the reactive lymphocyte blastogenesis index during the first weeks of infection and the phytohaemagglutinin response was seen to fall progressively. The antiglobulin reaction usually became positive after infection but neither antinuclear nor antierythrocyte antibodies were found. Precipitating antibodies to several polynucleotides were frequently present and were unrelated to infection or to Poly IC treatment.  (+info)

Deposition of IgA in renal glomeruli of mink affected with Aleutian disease. (8/70)

The glomerular deposition of immunoglobulin (Ig) was studied in sapphire mink affected with terminal Aleutian disease (AD). Fluorescein conjugated Ig-class specific antiserums were used to evaluate and identify the glomerular Ig. Kidneys of all 28 mink with documented AD had deposits of IgA and beta 1 C in a capillary and mesangial distribution. Only 7 of 28 mink had demonstrable glomerular IgG and/or IgM. In addition, interstitial plasma cell infiltrates in 17 of 19 kidneys stained exclusively with anti-IgA. All antiserums used in this study were evaluated for Ig-class specificity by both gel diffusion and agarose-bead techniques. The striking Ig class restriction demonstrated for glomerular Ig deposition in AD is discussed in light of current knowledge of the pathogenesis of AD glomerulopathy.  (+info)

A slow progressive disease of mink caused by the ALEUTIAN MINK DISEASE VIRUS. It is characterized by poor reproduction, weight loss, autoimmunity, hypergammaglobulinemia, increased susceptibility to bacterial infections, and death from renal failure. The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are particularly susceptible ...
A slow progressive disease of mink caused by the ALEUTIAN MINK DISEASE VIRUS. It is characterized by poor reproduction, weight loss, autoimmunity, hypergammaglobulinemia, increased susceptibility to bacterial infections, and death from renal failure. The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are particularly susceptible.
Alexandersen, Soren, Uttenthal-Jensen, A and Aasted, B 1986, Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. Brief report., Archives of Virology, vol. 87, no. 1-2, pp. 127-133, doi: 10.1007/BF01310549. ...
Aleutian mink disease virus (AMDV) readily spread within farmed mink and causes chronic infections with significant impacts for welfare and economy. In the present study a currently circulating Danish AMDV strain was used to induce chronic experimental infection of farmed mink.PCR was used to detect viral DNA in full blood, organs, faeces and oro-nasal swabs weekly for the first 8 weeks and then biweekly for another 16 weeks after AMDV challenge inoculation of wild type mink. The mink (n=29) was infected and seroconverted 2-3 weeks after AMDV inoculation and AMDV antibodies persisted during the maximum experimental period of 24 weeks. Viraemia and faecal excretion of viral DNA was detected in the mink (n=29) at various and intermittent time intervals. Excretion of viral DNA in oro-nasal swabs was detected for 1-8 weeks in 21 mink. This highlights the risk of transmitting AMDV between infected farms.PCR was successfully used to detect viral DNA in organs 8, 16 and 24 weeks after AMDV inoculation ...
Aleutian mink disease virus (AMDV) is widespread among ranched and free-ranging American mink in Canada, but there is no information on its prevalence in other wild animal species. This paper describes the prevalence of AMDV of 12 furbearing species in Nova Scotia (NS), Canada. Samples were collected from carcasses of 462 wild animals of 12 furbearing species, trapped in 10 NS counties between November 2009 and February 2011. Viral DNA was tested by PCR using two primer pairs, and anti-viral antibodies were tested by counterimmunoelectrophoresis (CIEP) on spleen homogenates. Positive PCR or CIEP samples were detected in 56 of 60 (93.3%) American mink, 43 of 61 (70.5%) short-tailed weasels, 2 of 8 (25.0%) striped skunks, 2 of 11 (18.2%) North American river otters, 9 of 85 (10.6%) raccoons, and 2 of 20 (10.0%) bobcats. Samples from six fishers, 24 coyotes, 25 red foxes, 58 beavers, 45 red-squirrels and 59 muskrats were negative. Antibodies to AMDV were detected by CIEP in 16 of 56 (28.6%) mink and one of
TY - GEN. T1 - Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme. AU - Kvisgaard, Lise Kirstine. AU - Hansen, Mette Sif. AU - Chriél, Mariann. AU - Larsen, Lars Erik. AU - Hjulsager, Charlotte Kristiane. PY - 2018. Y1 - 2018. M3 - Konferencebidrag i proceedings. SP - 90. EP - 94. BT - Kopenhagen Fur Forskning. Faglig Årsberetning 2018. PB - Kopenhagen Fur Forskning. CY - Aarhus N. ER - ...
Journal of Wildlife Diseases publishes work on infectious, parasitic, toxic, nutritional, physiologic, and neoplastic diseases impacting wild animals.
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I have noticed an abundance of these American Mink along the shore this year. A few nights ago, I was having cocktails with a neighbor. We were sitting on her porch overlooking the water. Suddenly, a mink bounced onto the lawn, stood on its hind legs while studying us, then bounced away back down to the rocks. I have seen them numerous times in front of our house while NOT under the influence of Martinis. Our dog yodels wildly when he sees one darting amongst the rocks. I took these photos on Little Wood Island which sits about two miles off the coast of Phippsburg on the west side. This is an American Mink. You can tell its not a European Mink by its accent. Actually, European Minks are distinguishable by a white mark on their head. They are an introduction to our ecology and do not fare as well as the American Mink. Our mink eats anything. In the wild they eat small fish and other marine life caught in tidal pools and small birds. Ive seen them most often at low tide, hunting the stranded ...
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The Pamfletti zine was published in September 93 in conjunction with The Pastels/Stereolab gigs in Edinburgh and Glasgow. Here are some highlights ...
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H9N2 is one of the major subtypes of influenza virus circulating in poultry in China, which has a wide host range from bird to mammals. Two H9N2 viruses were isolated from one mink farm in 2014. Phylogenetic analysis showed that internal genes of the H9N2 viruses have close relationship with those of H7N9 viruses. Interestingly, two H9N2 were separated in phylogenetic trees, indicating that they are introduced to this mink farm in two independent events. And further mice studies showed that one H9N2 caused obvious weight loss and 20% mortality in infected mice, while another virus did not cause any clinical sign in mice infected at the same dose ...
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immune Uncategorized Olmesartan medoxomil manufacture, PT141 Acetate/ Bremelanotide Acetate Background Mink enteritis pathogen (MEV) causes mink viral enteritis, an acute and contagious disease whose medical indications include violent diarrhea highly, and which is seen as a high mortality and morbidity. 246 Olmesartan medoxomil manufacture scientific mink samples gathered from five provinces in North-Eastern China, 50.8% were scored MEV positive by our nanoPCR assay, weighed against 32.5% for conventional PCR. Furthermore no combination reactivity was noticed for the nanoPCR assay regarding related infections, including dog distemper pathogen (CDV) and Aleutian mink disease parvovirus (AMDV). Phylogenetic evaluation of four Chinese language outrageous type MEV isolates using the nanoPCR assay indicated that they belonged to a little MEV clade, called China type, in the MEV/FPLV cluster, and were clustered in the same area closely. Conclusions Our outcomes indicate the fact that MEV China type ...
Trautwein, G.; Schneider, P.; Ernst, E., 1974: Studies on the pathogenesis of Aleutian disease in mink. VIII. Depression of antibody formation against horseradish peroxidase
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Aleutian+Mink+Disease at the US National Library of Medicine Medical Subject Headings (MeSH) Aleutian+Mink+Disease+Virus at the ... Aleutian mink disease virus). Diseases associated with this genus include progressive disorder of immune system. Group: ssDNA ... Cheng F, Chen AY, Best SM, Bloom ME, Pintel D, Qiu J (March 2010). "The capsid proteins of Aleutian mink disease virus activate ... "Driving forces behind the evolution of the Aleutian mink disease parvovirus in the context of intensive farming". Virus ...
A different parvovirus causes aleutian disease in mink and other mustelids, characterized by lymphadenopathy, splenomegaly, ... Aleutian mink disease virus), vii) Aveparvovirus (e.g. chicken parvovirus) and viii) Copiparvovirus (e.g. bovine parvovirus 2). ... Disease information on Parvoviridae[edit]. The remainder of this article discusses the disease-causing Parvoviridae. ... 4 Disease information on Parvoviridae *4.1 Diseases caused by members of the Parvoviridae family ...
Aleutian disease virus (ADV) is a parvovirus discovered among mink in the Aleutian Islands in the early 20th century. In ... It has also been suggested that there may be a hereditary component to adrenal disease. Adrenal disease is usually detected ... Ferrets treated for adrenal disease may temporarily have severe hair loss as their bodies recover from the disease. Insulinoma ... which treat the symptoms but not the disease itself, and/or hormone therapy. The causes of adrenal disease are as yet uncertain ...
... aleutian mink disease virus MeSH B04.280.580.650.600.325 - feline panleukopenia virus MeSH B04.280.580.650.600.550 - mice ... aleutian mink disease virus MeSH B04.909.204.671.650.600.325 - feline panleukopenia virus MeSH B04.909.204.671.650.600.550 - ... mink cell focus-inducing viruses MeSH B04.909.574.807.375.525.596 - moloney murine leukemia virus MeSH B04.909.574.807.375.525. ... mink cell focus-inducing viruses MeSH B04.909.777.731.375.525.596 - moloney murine leukemia virus MeSH B04.909.777.731.375.525. ...
Aleutian mink disease MeSH C20.673.774.535 - granulomatous disease, chronic MeSH C20.673.774.600 - Job's syndrome MeSH C20.683. ... Still's disease, adult-onset MeSH C20.111.258.250 - demyelinating autoimmune diseases, cns MeSH C20.111.258.250.175 - diffuse ... heavy chain disease MeSH C20.683.780.490.512 - immunoproliferative small intestinal disease MeSH C20.683.780.640 - monoclonal ... Hodgkin disease MeSH C20.683.515.761.480 - lymphoma, non-Hodgkin MeSH C20.683.515.761.480.150 - lymphoma, b-cell MeSH C20.683. ...
... carries Aleutian mink disease, heartworm, West Nile virus[citation needed] Ochlerotatus flavescens Carries heartworm, Western ...
... aleutian mink disease MeSH C02.256.700.300 - erythema infectiosum MeSH C02.256.700.363 - feline panleukopenia MeSH C02.256. ... kyasanur forest disease MeSH C02.782.417.505 - lassa fever MeSH C02.782.417.560 - marburg virus disease MeSH C02.782.417.762 - ... swine vesicular disease MeSH C02.782.687.484 - foot-and-mouth disease MeSH C02.782.791.142 - african horse sickness MeSH ... kyasanur forest disease MeSH C02.081.885.550 - nairobi sheep disease MeSH C02.182.500.300 - encephalitis, viral MeSH C02.182. ...
... was first recognized in ranch-raised mink in 1956. The disease was so named because it was first found in mink ... Aleutian disease, also known as mink plasmacytosis, is a disease which causes spontaneous abortion and death in minks and ... The disease spread from minks to ferrets, as the two were raised on the same farms. Aleutian disease has also more currently ... Once symptoms have been indicated, the mink is certain to die. A lethal infection in mink, the Aleutian disease virus lies ...
Aleutian disease European mink Sea mink Fur farming Reid, F.; Schiaffini, M.; Schipper, J. (2016). "Neovison vison". IUCN Red ... Transmissible mink encephalopathy (TME) is a prion disease of mink, similar to BSE in cattle and scrapie in sheep. A 1985 ... The American mink and European mink have both been found to transmit SARS-CoV-2, the virus that causes COVID-19. American minks ... Domestic mink are larger than wild mink, which may cause problems with the ecosystem when they escape. Minks are solitary, ...
... in flow measurement Acoustic droplet vaporization Adventure type of visual novel Aleutian Disease Virus, a disease of ferrets ... and minks, or the virus that causes it Andover Airfield, Hampshire, UK (IATA airport code) Andover railway station, UK ( ...
The beginning of the river lies in the Aleutian Range. The first six miles of the river run slowly through the tundra. ... Along the river, beaver, foxes, wolverines, mink, and otter are all found as well occasional wolf. In the water, there are ... After the decimation of natives by the disease, white human settlement around the Alagnak increased rapidly. In June 1927 ...
The largest producer of mink and foxes is Nova Scotia which in 2012 generated revenues of nearly $150 million and accounted for ... The maritime fur trade was pioneered by the Russians, working east from Kamchatka along the Aleutian Islands to the southern ... as well as epidemic diseases. The trade's effect on China and Europe was minimal. For New England, the maritime fur trade and ... depopulation due to epidemic disease, and enhanced importance of totems and traditional nobility crests. The indigenous culture ...
Regions in the world with similar climates include the Aleutian Islands, the Alaska Peninsula, and Tierra del Fuego, although ... It views the database, called Íslendingabók, as a valuable tool for conducting research on genetic diseases, given the relative ... Wild mammals include the Arctic fox, mink, mice, rats, rabbits, and reindeer. Polar bears occasionally visit the island, ... Natural disasters, including volcanic eruption and disease, contributed to a decreasing population. In the summer of 1627, ...
... in central Ontario carried both toxoplasmosis and Aleutian disease, but neither affliction was suspected to ... slender-bodied weasel about the size of a mink with relatively large rounded ears, short limbs, and a bushy tail. American ... 1990). The effects of disease, prey fluctuation, and clear cutting on American marten in Newfoundland. Logan, UT: Utah State ...
In turn, Finnish white-tailed eagles have become the main natural control and may inhibit the mink from breeding via heavy ... Bald eagle juveniles may be found together with white-tailed eagles in the Aleutian islands (where the white-tailed eagle ... Alexander, T. L., & Buxton, D. (Eds.). (1986). Management and diseases of deer: a handbook for the veterinary surgeon. ... Murie, O. J. (1959). Fauna of the Aleutian Islands and Alaska peninsula. North American Fauna, 1-364. Tobish Jr, T. G., & Balch ...
Little effort has gone into assessing the threat of disease to wild North American river otter populations, so it is poorly ... The North American river otters may compete with the American mink (Mustela vison) for resources. In Alaska, the two species ... The species is also present throughout Alaska, including the Aleutian Islands, and the north slope of the Brooks Range. However ... Gilbert, F.F.; E.G. Nancekivell (1982). "Food habits of mink (Mustela vison) and otter (Lutra canadensis) in northeastern ...
a b Salo, P., Nordström, M., Thomson, R. L., & Korpimäki, E. (2008). Risk induced by a native top predator reduces alien mink ... Alexander, T. L., & Buxton, D. (Eds.). (1986). Management and diseases of deer: a handbook for the veterinary surgeon. ... Murie, O. J. (1959). Fauna of the Aleutian Islands and Alaska peninsula. North American Fauna, 1-364. ... Conversely, the white-tailed eagle have not been known to prey on the critically endangered, native European mink (Mustela ...
ISBN 0-00-219728-6. Takken, Willem; Knols, Bart G J (editors) (2007). Emerging pests and vector-borne diseases in Europe. ... like the Aleutian tern, may wander far from land. The sooty tern is entirely oceanic when not breeding, and healthy young birds ... such as the American mink in Scotland, presents an unfamiliar threat. Adult terns may be hunted by owls and raptors, and their ...
Although disease has clearly contributed to the deaths of many of California's sea otters, it is not known why the California ... In the Aleutian Islands, a massive and unexpected disappearance of sea otters has occurred in recent decades. In the 1980s, the ... The extinct sea mink of northeastern North America is another mustelid that had adapted to a marine environment. Three ... In the eastern Pacific Ocean, E. l. kenyoni, the northern sea otter, is found from Alaska's Aleutian Islands to Oregon and E. l ...
American mink) from North America Procyon lotor (common raccoon) from North America Myocastor coypus (nutria) from South ... Emerging Infectious Diseases. 10 (3): 494-496. doi:10.3201/eid1003.030257. PMC 3322806. PMID 15109420. "Puerto Rico killing ... and Umnak Island in the Aleutian Archipelago from mainland Alaska Lepus europaeus (European hare) From Europe Oryctolagus ... Guyana and Suriname American mink Dog Cat Chital from Asia to Argentina, Brazil, Uruguay and Chile Elk from North America Red ...
Journal of Wildlife Diseases 35:187-193. Kaler, R. S., Kenney, L. A., Bond, A. L., & Eagles-Smith, C. A. (2014). Mercury ... In North America, the breeding range has been known in modern times to include the Aleutians (i.e. Buldir and Attu) and much of ... American mink (Mustela vision), and striped skunk (Mephitis mephitis). Given the large size of some of this prey, it can be ... In North America, they occasionally regularly winter in the Aleutian island chain and do so broadly and with a fair amount of ...
In the late 19th century, it was introduced into the Aleutian Islands southwest of Alaska. It mostly inhabits tundra and pack ... treating a population imperilled by disease". Oryx. 30 (4): 251-258. doi:10.1017/S0030605300021748.. ... European mink (M. lutreola). *Indonesian mountain weasel (M. lutreolina). *Black-footed ferret (M. nigripes) ... They were transported to various previously fox-free Aleutian Islands during the 1920s. The program was successful in terms of ...
Nevertheless, a genetic bottleneck is present in the existing population, which could make it more susceptible to disease and ... they migrate northwards to their feeding grounds along the continental shelf from Washington to the western Aleutians in Alaska ... European mink (M. lutreola). *Indonesian mountain weasel (M. lutreolina). *Black-footed ferret (M. nigripes) ...
Enlarged, pitted, pale tan kidneys seen in an advanced case of Aleutian disease of mink. ... From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health ...
"Aleutian Mink Disease" by people in Harvard Catalyst Profiles by year, and whether "Aleutian Mink Disease" was a major or minor ... A slow progressive disease of mink caused by the ALEUTIAN MINK DISEASE VIRUS. It is characterized by poor reproduction, weight ... The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are ... "Aleutian Mink Disease" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ...
However, 2 mink farmers with vascular disease and microangiopathy similar to that in mink with Aleutian disease were found to ... These findings raise the suspicion that AMDV may play a role in human disease. ... Reports of a possible relationship between Aleutian mink disease parvovirus (AMDV) and human infection are rare. ... However, 2 mink farmers with vascular disease and microangiopathy similar to that in mink with Aleutian disease were found to ...
However, 2 mink farmers with vascular disease and microangiopathy similar to that in mink with Aleutian disease were found to ... such as Aleutian mink disease virus (AMDV), cause a broad spectrum of diseases in animals and man. Acute disease manifests ... Aleutian Mink Disease Virus and Humans. Emerging Infectious Diseases. 2009;15(12):2040-2042. doi:10.3201/eid1512.090514.. ... Evidence of restricted viral replication in adult mink infected with Aleutian disease of mink parvovirus. J Virol. 1988;62:1495 ...
Journal of Wildlife Diseases publishes work on infectious, parasitic, toxic, nutritional, physiologic, and neoplastic diseases ... ANTIBODIES TO ALEUTIAN MINK DISEASE PARVOVIRUS IN FREE-RANGING EUROPEAN MINK (MUSTELA LUTREOLA) AND OTHER SMALL CARNIVORES FROM ... EVALUATION OF THE BIONIC® TRAP TO QUICKLY KILL MINK (MUSTELA... ALEUTIAN MINK DISEASE PARVOVIRUS IN WILD RIPARIAN CARNIVORES IN ... "ANTIBODIES TO ALEUTIAN MINK DISEASE PARVOVIRUS IN FREE-RANGING EUROPEAN MINK (MUSTELA LUTREOLA) AND OTHER SMALL CARNIVORES FROM ...
The transplacental transmission of Aleutian mink disease parvovirus (ADV) was studied in experimental infection of 1-year-old ... N2 - The transplacental transmission of Aleutian mink disease parvovirus (ADV) was studied in experimental infection of 1-year- ... AB - The transplacental transmission of Aleutian mink disease parvovirus (ADV) was studied in experimental infection of 1-year- ... Broll S, Alexandersen S. Investigation of the pathogenesis of transplacental transmission of Aleutian mink disease parvovirus ...
Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme. Kopenhagen Fur Forskning. Faglig ... Kvisgaard, LK, Hansen, MS, Chriél, M, Larsen, LE & Hjulsager, CK 2018, Forsøg med inaktivering af aleutian mink disease virus ( ... Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme. In Kopenhagen Fur Forskning. ... title = "Fors{\o}g med inaktivering af aleutian mink disease virus (AMDV) i gylle ved h{\o}j PH eller varme", ...
The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are ... A slow progressive disease of mink caused by the ALEUTIAN MINK DISEASE VIRUS. It is characterized by poor reproduction, weight ...
Aleutian Mink Disease. Aleutian Mink Disease Virus. Animals. Immunosorbent Techniques. Liver. Lung. Mink. Molecular Weight. ... Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. ... Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. ... Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. ...
Aleutian mink disease diagnostics. Certified production of two types of tests (CIEP- and ELISA-based), which allow detection of ... antibodies specific for the AMDV (viral plasmacytosis) in the blood of minks. Custom services and troubleshooting the ...
... is the causative agent of Aleutian disease (AD), which affects mink of all genotypes and also infects other mustelids such as ... Mink in the wild carry viruses with high intra-host diversity and are occasionally even co-infected by two different strains, ... as well as from free-ranging mink. The data set was supplemented with partial genomes obtained from 26 strains. The sequences ... suggesting that free-ranging mink tolerate chronic infections for extended periods of time. These findings highlight the need ...
Aleutian Mink Disease. Aleutian Mink Disease Virus. Animals. Antibodies, Viral. Counterimmunoelectrophoresis. Electrophoresis, ... Restricted heterogeneity of the early antibody response to Aleutian disease virus in mink kits.. Alexandersen, Soren and Aasted ... Restricted heterogeneity of the early antibody response to Aleutian disease virus in mink kits. ... B 1986, Restricted heterogeneity of the early antibody response to Aleutian disease virus in mink kits., Acta Pathologica ...
Antibodies to AMDV were detected by CIEP in 16 of 56 (28.6%) mink and one of the 8 skunks (12.5%). Thirteen of the mink were ... Positive PCR or CIEP samples were detected in 56 of 60 (93.3%) American mink, 43 of 61 (70.5%) short-tailed weasels, 2 of 8 ( ... Positive CIEP or PCR animals were present in all nine counties from which mink or weasel samples were collected. The presence ... The mechanism of virus transmission between wildlife and captive mink and the effects of AMDV exposure on the viability of the ...
Aleutian Mink Disease Virus and Humans Jørgen R. Jepsen. , Francesco dAmore, Ulrik Baandrup, Michael Roost Clausen, Elisabeth ... of abdominal aortic biopsy sample from 35-year-old mink farmer in Denmark who had been exposed to Aleutian mink disease ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ...
... A total of 24 mink were infected with the virus of Aleutian disease and groups of 4 were killed at intervals of 4 weeks. Each ... Trautwein, G.; Schneider, P.; Ernst, E., 1974: Studies on the pathogenesis of Aleutian disease in mink. VIII. Depression of ... Studies on the pathogenesis of Aleutian disease in mink. VIII. Depression of antibody formation against horseradish peroxidase ...
Aleutian mink disease virus (AMDV) readily spread within farmed mink and causes chronic infections with significant impacts for ... Aleutian mink disease virus; AMDV; Mink; PCR; Counter current immunoelectrophoresis; Chronic experimental infection; The ... Monitoring chronic infection with a field strain of Aleutian mink disease virus. * ... Four of 6 sapphire mink were infected indirectly via the AMDV inoculated wild type mink whereas the other 2 sapphire mink ...
Histopathologic and immunohistochemical lesions in liver of mink infected with Aleutian disease virus - Polish Journal of ... Histopathologic and immunohistochemical lesions in liver of mink infected with Aleutian disease virus Journal title. Polish ... Histopathologic and immunohistochemical lesions in liver of mink infected with Aleutian disease virus. A. Valdovska; M. Pilmane ... Mink: Biology, health and disease, 21. ; S Hsu (1981), The use of antiavidin antibody and avidin-biotin - peroxidase complex in ...
Aleutian disease (AD), caused by Aleutian mink disease virus (AMDV), is a serious problem for the multi-million-dollar mink ... Relationships Between Severity of Histopathological Lesions of Aleutian Disease in Mink, Measured by Digital Image Analysis, ... Selecting mink that can tolerate the infection is a viable way to control the problem. The first objective of this study was to ... liver and heart of 299 black mink, inoculated with a local strain of AMDV and monitored for up to 3.5 years, were generally ...
Replication of Aleutian mink disease parvorivus in lymphoid tissues of adult mink: Involvement of follicular dendritic cells ... Replication of Aleutian mink disease parvorivus in lymphoid tissues of adult mink: Involvement of follicular dendritic cells ... Replication of Aleutian mink disease parvorivus in lymphoid tissues of adult mink : Involvement of follicular dendritic cells ... title = "Replication of Aleutian mink disease parvorivus in lymphoid tissues of adult mink: Involvement of follicular dendritic ...
... supplementation on survival rate and reproductive performance of mink challenged with Aleutian mink disease virus Effects of ... supplementation on survival rate and reproductive performance of mink challenged with Aleutian mink disease virus ...
Molecular epidemiology of Aleutian mink disease virus causing outbreaks in mink farms from Southwestern Europe: a retrospective ... Molecular epidemiology of Aleutian mink disease virus causing outbreaks in mink farms from ... [email protected]#Aleutian mink disease virus (AMDV) causes major economic losses in fur-bearing animal production. The control of ... helps assess the possible origin of AMDV infections in mink farms and improving the control and prevention of this disease. ...
Aleutian disease virus of mink; and transmissible spongiform encephalopathies (TSEs or prion diseases) such as scrapie, bovine ... Laboratory of Viral Diseases. Laboratory of Viral Diseases (LVD) studies the basic mechanisms of viral entry into cells, ... Laboratory of Parasitic Diseases (LPD) conducts basic and clinical studies to prevent, control, and treat diseases caused by ... Laboratory of Infectious Diseases. Laboratory of Infectious Diseases (LID) focuses on viral vaccine development, host immune ...
Aleutian mink disease virus in free-ranging mink from Sweden. Persson, S., Jensen, T. H., Blomström, A. L., Appelberg;m, M. T ...
Evolutionary analysis of whole-genome sequences confirms inter-farm transmission of Aleutian mink disease virus Hagberg, Emma ... Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies Boyd, Mette ; ...
Forsøg med inaktivering af aleutian mink disease virus (AMDV) i gylle ved høj PH eller varme Kvisgaard, Lise Kirstine ; Hansen ... Forbedret diagnostik af mink enteritis virus (MEV) Kvisgaard, Lise Kirstine ; Holm, Elisabeth ; Chriél, Mariann ; Larsen, Lars ... Eksperimentel smitte af mink med plasmacytosevirus i foder Hjulsager, Charlotte Kristiane ; Lazov, Christina Marie ; Chriél, ... Immunologisk respons mod mink astrovirus Mathiesen, Ronja ; Kvisgaard, Lise Kirstine ; Chriél, Mariann ; Struve, Tina ; ...
Aleutian mink disease virus (ADV). *Rabbit hemorragic disease virus (RHDV). I sektionen udføres der udover overvågning og ... og human influenzavirus samt aviær influenza og Newcastle disease virus. ...
aleutian mink disease. *aleutian disease. basal cell carcinoma. *basal cell cancer. *1342967 ... Additional Disease Information for MMP11 Genetic Association Database (GAD) Human Genome Epidemiology Navigator (HuGE) ATLAS of ... Disease Links. Group. Role. Mechanism of Action. Clinical Trials. Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2- ... Gene Damage Index Score: 2.74; 46.78% of all genes are more intolerant (likely to be disease-causing) ...
Aleutian mink disease virus in furbearing mammals in Nova Scotia, Canada Aleutian mink disease virus (AMDV) is widespread among ... Wildlife Diseases. Here we present a collection of articles published in Acta Veterinaria Scandinavica advancing our knowledge ... Rabies is a disease of global significance including in the circumpolar Arctic. In Alaska enzootic rabies persist in northern ... Arcanobacterium phocae infection in mink (Neovison vison), seals (Phoca vitulina, Halichoerus grypus) and otters (Lutra lutra) ...
Three-dimensional structure of Aleutian mink disease parvovirus: implications for disease pathogenicity. ...
  • Reports of a possible relationship between Aleutian mink disease parvovirus (AMDV) and human infection are rare. (cdc.gov)
  • Histopathologic appearance of abdominal aortic biopsy sample from 35-year-old mink farmer in Denmark who had been exposed to Aleutian mink disease parvovirus−infected mink for 10 years (patient 1). (cdc.gov)
  • In order to investigate the possible role of Aleutian disease parvovirus (ADV) in decline of the species, a serologic survey was conducted from March 1996 to March 2002 in 420 free-ranging individuals of six species of small carnivores distributed in eight départements of southwestern France. (bioone.org)
  • The transplacental transmission of Aleutian mink disease parvovirus (ADV) was studied in experimental infection of 1-year-old female non-Aleutian mink. (dtu.dk)
  • Characterization of Aleutian disease virus as a parvovirus. (microbiologyresearch.org)
  • Nucleotide sequence of the 5'-terminal palindrome of Aleutian mink disease parvovirus and construction of an infectious molecular clone. (microbiologyresearch.org)
  • Qiu J , Cheng F , Pintel D . The abundant R2 mRNA generated by aleutian mink disease parvovirus is tricistronic, encoding NS2, VP1, and VP2. (microbiologyresearch.org)
  • Molecular characterization of the small nonstructural proteins of parvovirus Aleutian mink disease virus (AMDV) during infection. (microbiologyresearch.org)
  • By using strand-specific in situ hybridization and immunohistochemistry, evidence for replication of the Aleutian mink disease parvovirus was observed in cells resembling macrophages and cells resembling follicular dendritic cells at 10 days after infection but only in macrophages at 60 days. (elsevier.com)
  • Sequestration of the Aleutian mink disease parvovirus in larger numbers of macrophages and follicular dendritic cells was noted at both 10 and 60 days. (elsevier.com)
  • It is caused by Carnivore amdoparvovirus 1 (also known as Aleutian disease virus, ADV), a highly contagious parvovirus in the genus Amdoparvovirus. (wikipedia.org)
  • Type species of the Parvovirinae include minute virus of mice, human parvovirus, and Aleutian mink disease virus. (britannica.com)
  • The Aleutian Disease Virus in ferrets (ADV) is a type of parvovirus, which gets its name from a strain of minks, as the virus was first detected in them. (pethealthandcare.com)
  • Aleutian mink disease virus, 25 feline panleukopenia virus (FPLV), 26 human parvovirus B19, 27 - 29 parvovirus H-1, 30 and rat parvovirus 31 have been reported to induce apoptotic cell death while bovine parvovirus infected cells are necrotic. (pubmedcentralcanada.ca)
  • Viuff B, Aasted B, Alexandersen S (1994) Role of alveolar type II cells and of surfactant-associated protein C mRNA levels in the pathogenesis of respiratory distress in mink kits infected with aleutian mink disease parvovirus. (springer.com)
  • 0:14 Skip to 0 minutes and 14 seconds In this step we are going to focus on the parvovirus, which are one of the most common causes of disease amongst pets, but also in other species. (futurelearn.com)
  • Finally, Erythroparvovirus contains an important pathogen of humans, parvovirus B19, which produces the so-called "fifth disease" in children, a type of erythema. (futurelearn.com)
  • To research whether a DNA trojan may evade passive immunotherapy using a polyclonal antiserum, we analyzed the security of the neutralizing capsid antiserum against a lethal an infection from the immunosuppressive strain of the parvovirus minute disease of mice (MVMi) in 42 immunodeficient mice over a period of 200 days. (mingsheng88.org)
  • These results strengthen our earlier report within the quick evolutionary capacity of this mammalian-specific DNA disease in vivo LP-533401 cost and indicate the NS2-CRM1 interaction is an important determinant of parvovirus virulence that can be modulated in nature, hampering the effectiveness of passive antibody therapies in the LP-533401 cost long term. (mingsheng88.org)
  • Furthermore no combination reactivity was noticed for the nanoPCR assay regarding related infections, including dog distemper pathogen (CDV) and Aleutian mink disease parvovirus (AMDV). (immune-source.com)
  • Aleutian mink disease parvovirus (ADV) infects macrophages but infection is restricted. (usda.gov)
  • Aleutian mink disease parvovirus (AMDV) causes a persistent infection associated with immune complex disease, hypergammaglobulinemia, and high levels of antiviral antibodies. (bvsalud.org)
  • However, 2 mink farmers with vascular disease and microangiopathy similar to that in mink with Aleutian disease were found to have AMDV-specific antibodies and AMDV DNA. (cdc.gov)
  • These findings raise the suspicion that AMDV may play a role in human disease. (cdc.gov)
  • Autonomous parvoviruses, such as Aleutian mink disease virus (AMDV), cause a broad spectrum of diseases in animals and man. (cdc.gov)
  • In adult mink, AD is a persistent, slowly progressive AMDV infection in which a dysregulated immune system and a postinfectious antibody response cause an immune complex-mediated vasculitis ( 2 ). (cdc.gov)
  • Histopathologic features like those in AMDV-infected mink have been described for 2 patients in the early 1960s ( 10 ). (cdc.gov)
  • however, injection of their antibody-positive blood into Aleutian mink caused neither lesions nor AMDV-antibody production ( 11 ). (cdc.gov)
  • We report finding anti-AMDV antibodies and AMDV genome in tissue from 2 mink farmers with relevant virus exposure and clinical disease similar to that in mink with AD. (cdc.gov)
  • Patient 1 was a mink farmer who had been exposed to AMDV-infected mink for 10 years. (cdc.gov)
  • Certified production of two types of tests (CIEP- and ELISA-based), which allow detection of antibodies specific for the AMDV (viral plasmacytosis) in the blood of minks. (imgenplus.com)
  • Aleutian mink disease virus (AMDV) is the causative agent of Aleutian disease (AD), which affects mink of all genotypes and also infects other mustelids such as ferrets, martens and badgers. (microbiologyresearch.org)
  • Here, we investigated the diversity and evolution of Finnish AMDV strains by sequencing the complete coding sequences of 31 strains from mink originating from farms differing in their virus history, as well as from free-ranging mink. (microbiologyresearch.org)
  • Aleutian mink disease virus (AMDV) is widespread among ranched and free-ranging American mink in Canada, but there is no information on its prevalence in other wild animal species. (biomedcentral.com)
  • The presence of AMDV in so many species across the province has important epidemiological ramifications and could pose a serious health problem for the captive mink, as well as for susceptible wildlife. (biomedcentral.com)
  • The mechanism of virus transmission between wildlife and captive mink and the effects of AMDV exposure on the viability of the susceptible species deserve further investigation. (biomedcentral.com)
  • Information on the prevalence of AMDV in wildlife in Eastern Canada is limited to one report on the feral American mink[ 3 ]. (biomedcentral.com)
  • The primary objective of this study was to survey the prevalence of AMDV in wild furbearing species in Nova Scotia (NS), the largest ranched mink pelt producing province in Canada. (biomedcentral.com)
  • Aleutian mink disease virus (AMDV) readily spread within farmed mink and causes chronic infections with significant impacts for welfare and economy. (forskningsdatabasen.dk)
  • In the present study a currently circulating Danish AMDV strain was used to induce chronic experimental infection of farmed mink.PCR was used to detect viral DNA in full blood, organs, faeces and oro-nasal swabs weekly for the first 8 weeks and then biweekly for another 16 weeks after AMDV challenge inoculation of wild type mink. (forskningsdatabasen.dk)
  • The mink (n=29) was infected and seroconverted 2-3 weeks after AMDV inoculation and AMDV antibodies persisted during the maximum experimental period of 24 weeks. (forskningsdatabasen.dk)
  • This highlights the risk of transmitting AMDV between infected farms.PCR was successfully used to detect viral DNA in organs 8, 16 and 24 weeks after AMDV inoculation with only minor differences between these weeks which is of diagnostic interest.This AMDV challenge model was also used to mimic natural infection of susceptible sapphire mink. (forskningsdatabasen.dk)
  • Four of 6 sapphire mink were infected indirectly via the AMDV inoculated wild type mink whereas the other 2 sapphire mink remained uninfected. (forskningsdatabasen.dk)
  • Aleutian disease (AD), caused by Aleutian mink disease virus (AMDV), is a serious problem for the multi-million-dollar mink industry in Nova Scotia. (dal.ca)
  • The first objective of this study was to develop a quantitative method of measuring the severity of histopathological lesions in the kidneys, liver and heart of AMDV-infected mink, using digital image analysis (DIA) software. (dal.ca)
  • The second objective was to assess relationships between the severity of AD lesions, assessed by DIA, and anti-AMDV antibody titer and serum gamma-globulin level, which are believed to be indicators of the severity of AD lesions in infected mink. (dal.ca)
  • A reproducible and reliable method was developed for the calculation of the percent infiltrated mononuclear cells on H&E stained slides of the kidneys, liver and heart of AMDV-infected mink. (dal.ca)
  • Associations between antibody titer and gamma-globulin level and percent infiltrated mononuclear cells measured by DIA software in the kidneys, liver and heart of 299 black mink, inoculated with a local strain of AMDV and monitored for up to 3.5 years, were generally weak, making the serological measures unreliable tools for the identification of tolerant mink, particularly when the time of infection is unknown. (dal.ca)
  • [email protected]# Aleutian mink disease virus (AMDV) causes major economic losses in fur-bearing animal production . (bvsalud.org)
  • [email protected]#The combination of phylogenetic inference , together with epidemiological data, helps assess the possible origin of AMDV infections in mink farms and improving the control and prevention of this disease . (bvsalud.org)
  • Aleutian mink disease virus (AMDV) is a member of the parvoviridae family which primarily affects mink, often resulting in death. (wisconsin.edu)
  • Body 2 Evaluation from the sensitivities of nanoPCR (a) and typical PCR (b) for the recognition of MEV plasmid DNA copies put through nanoPCR and … Specificity from the MEV nanoPCR assay Agarose gel electrophoresis evaluation indicated no combination result of the nanoPCR assay with CDV or AMDV DNAs, nor DNA extracted in the tissues of healthful minks, but was positive for MEV-infected minks (Body?3). (immune-source.com)
  • Mink plasmacytosis, caused by Aleutian Mink Disease Virus (AMDV), poses a threat to the development of the animal fur industry. (bvsalud.org)
  • Neutralizing antibodies against AMDV may result in a persistent infection rather than providing protection for minks. (bvsalud.org)
  • In order to eliminate mink plasmacytosis, antibody detection technology has been used globally as a dominant approach to screen for AMDV-positive minks. (bvsalud.org)
  • In addition, the role of cytokine IL-6 in ADE mediated disease development is discussed, to facilitate a better understanding of the pathogenesis of AMDV infection, as well as give insights into rational vaccine design approaches. (bvsalud.org)
  • Aleutian disease (AD) is known to produce clinical signs in mink and ferrets only ( 2 , 3 ), although other mammals have reportedly been antibody positive. (cdc.gov)
  • Aleutian disease, also known as mink plasmacytosis, is a disease which causes spontaneous abortion and death in minks and ferrets. (wikipedia.org)
  • The virus has been found as a natural infection in the Mustelidae family within mink, ferrets, otters, polecats, stone and pine martens and within other carnivores such as skunks, genets, foxes and raccoons. (wikipedia.org)
  • The disease spread from minks to ferrets, as the two were raised on the same farms. (wikipedia.org)
  • A lethal infection in mink, the Aleutian disease virus lies dormant in ferrets until stress or injury allows it to surface. (wikipedia.org)
  • Aleutian Disease in ferrets has become an increasing problem, affecting overall ferret health. (pethealthandcare.com)
  • The Aleutian Disease Virus in ferrets can survive in the environment, for a long period of time. (pethealthandcare.com)
  • Because this disease is fairly common, ferrets can suffer from it for a while, before showing any symptoms. (pethealthandcare.com)
  • Lawsonia intracellularis can cause a proliferative bowel disease, especially in younger ferrets. (merckvetmanual.com)
  • Two coronaviruses cause disease in ferrets. (merckvetmanual.com)
  • This disease is highly transmissible and is often brought into a group of ferrets by an asymptomatic juvenile animal. (merckvetmanual.com)
  • The disease is most severe in older ferrets, which may take months to fully recover. (merckvetmanual.com)
  • Most ferrets with active ADV die of liver or kidney failure at the end of the disease. (ferretclub.com)
  • The Pennsylvania Ferret Club & Shelter believes that until more is known about this disease, the only responsible thing that we can do when inviting hundreds of ferret owners and their ferrets to our events is to require that all ferrets in attendance have been tested for this disease. (ferretclub.com)
  • In fact, studies have shown that only a small percentage of ferrets that have tested positive for ADV will actually become clinically sick from the disease. (ferretclub.com)
  • At times these antibodies, which are produced in huge amounts, form complexes, which get deposited in the tissues and lead to inflammation, which eventually aggravates the disease. (pethealthandcare.com)
  • For new targets we consult with leading experts to accelerate development of antibodies that will propel state-of-the-art research in cellular health and disease. (abgent.com)
  • Sera from `regular' mink in colonies without overt disease got neither antigens nor antibodies detectable in precipitin testing. (healthappsopenday.com)
  • Sera from mink with spontaneously obtained Aleutian disease got a high occurrence of `nuclear' antigens and anti-DNA antibodies detectable in precipitin testing. (healthappsopenday.com)
  • The tests only show the presence of antibodies to ADV, which indicates only exposure to the disease. (ferretclub.com)
  • Plasmacytosis (Aleutian Disease) in feral mink in Iceland. (keldur.is)
  • Studies on the pathogenesis of Aleutian disease in mink. (geoscience.net)
  • Mink in the wild carry viruses with high intra-host diversity and are occasionally even co-infected by two different strains, suggesting that free-ranging mink tolerate chronic infections for extended periods of time. (microbiologyresearch.org)
  • There are different strains of this disease which have been documented. (wikipedia.org)
  • When different strains of Aleutian disease virus. (molecularstation.com)
  • Since there are different strains of ADV, it is believed that each strain may differ in the severity of the disease they cause. (pethealthandcare.com)
  • The coronavirus has spread and mutated in the Danish mink population, and now there have been cases of these strains jumping back into humans and causing infections there. (sciencemag.org)
  • reports have it that some of the current mink strains in Denmark are less susceptible to antibody responses. (sciencemag.org)
  • It has also been demonstrated that melatonin protects some strains of mink against Aleutian disease, and prevents the reduction of B- and T-cells as well as Th1 cytokine secretion in mice infected with leukemia retrovirus. (eattheapple.com)
  • Owing to the rapid decline of the European mink ( Mustela lutreola ) in France, a national conservation action plan has been initiated, in which scientific research to improve understanding of the causes of the decline is one of the primary objectives. (bioone.org)
  • The American Mink (mustela vision) is a member of the family of animals known as mustelids. (wildliferesponse.org)
  • Development of microsatellite markers in the American mink (Mustela vison). (dal.ca)
  • How dysregulation of the immune system results in immunodeficiencies, autoimmunity, inflammation, allergy, chronic infections, and lymphoproliferative diseases and what strategies might be valuable for therapeutic or vaccine development related to these conditions as well as cancer are important topics of interest, as is the behavior of the meta-organism. (nih.gov)
  • Some infections do not result in visible infection, while some manifest with visible effects, such as fifth disease (erythema infectiosum), which can give children a 'slapped-cheek' appearance. (wikipedia.org)
  • These bacteria are also common in several other infectious conditions in mink, such as urinary tract infections, pneumonia, and pleuritis. (biomedcentral.com)
  • Methods for treating cancer, viral diseases, respiratory and immune regulatory diseases, inflammations, infections and infestations by administering an acetylated mannan derivative, such as acemannan derived from aloe, are described. (google.es)
  • Reviews of infections with other "slow" viruses (Aleutian mink disease virus and lymphocytic choriomeningitis virus) emphasize a potential importance of immune and autoimmune reactions in the pathogenesis of some chronic nervous system disorders. (annals.org)
  • Parvoviruses can cause disease in some animals , including starfish and humans. (wikipedia.org)
  • The « missing link » between bats and humans could well be the mink - though the raccoon dog is also suspected. (reporterre.net)
  • Demonstration of non-degraded Aleutian disease virus (ADV) proteins in lung tissue from experimentally infected mink kits. (edu.au)
  • Background Mink enteritis pathogen (MEV) causes mink viral enteritis, an acute and contagious disease whose medical indications include violent diarrhea highly, and which is seen as a high mortality and morbidity. (immune-source.com)
  • Lesions can also be found within the pelt depending on the severity of the disease. (wikipedia.org)
  • This study presents the isolation of Arcanobacterium phocae from mink with severe skin lesions and other pathological conditions, and from wild seals and otters. (biomedcentral.com)
  • There are currently four species in this genus, including the type species Carnivore amdoparvovirus 1 (Aleutian mink disease virus). (wikipedia.org)
  • Aleutian disease virus-like virus (Amdoparvovirus sp. (elsevier.com)
  • Likewise, in the mink kits that survive, it infects the alveolar cells and ultimately causes respiratory distress, possibly leading to death. (wikipedia.org)
  • It was assumed that the disease was a result of poor genetics, but it was later found that minks of all coat colors were susceptible to the disease - but tend to have a lower mortality compared with Aleutian Mink. (wikipedia.org)
  • In four Danish mink ranches acute interstitial pneumonitis caused excessive mortality among kits within the first 2 1/2 months after parturition. (molecularstation.com)
  • Melatonin also postpones the onset of the disease produced by Semliki Forest virus inoculation and reduces the mortality of West Nile virus-infected mice stressed by either isolation or dexamethasone injection. (eattheapple.com)
  • In VEE-infected mice, melatonin postpones the onset of the disease and death for several days and reduces the mortality rate. (eattheapple.com)
  • The American mink shares the common characteristic of all mustelids: anal musk glands that are used for territory marking and defense. (wildliferesponse.org)
  • During the spring of 2015 till early winter 2015, 15 adult and eight juvenile mink ( Neovison vison ) carcasses, Nos. (biomedcentral.com)
  • Persistent viral shedding during asymptomatic Aleutian mink disease parvoviral infection in a ferret. (harvard.edu)
  • The diagnosis of this disease can be a little difficult and usually requires various tests to be performed on the ferret. (pethealthandcare.com)
  • It should be noted that neither of these tests can predict whether or not your ferret will actually become sick with ADV or if it will even spread the disease. (ferretclub.com)
  • The ferret is a small sleek fur-bearing mammal that belongs to the same Family as the otter, weasel, wolverine, and mink. (allferrets.org)
  • Unlike its cousins the otter, weasel, and mink, the pet ferret is not a wild animal. (allferrets.org)
  • Differential response of black mink to the Aleutian mink disease virus. (dal.ca)
  • Included in this symposium are reviews of chronic central nervous system diseases in animals produced by identifiable virus-like agents (CHINA), such as scrapie, rida, and visna in sheep, and encephalopathy in minks. (annals.org)
  • This is most commonly due to escapees within farms, who when free are hybridizing with wild mink. (wikipedia.org)
  • American mink farms are already known to be a reservoir for Aleutian disease. (sciencemag.org)
  • In 2015, A. phocae was isolated for the first time in Denmark from outbreaks of dermatitis in mink farms. (biomedcentral.com)
  • 1-23, (Table 1 ) originating from 12 mink farms (Fig. 1 ) were submitted to the National Veterinary Institute, Technical University of Denmark for laboratory examination. (biomedcentral.com)
  • It seems increasingly plausible that Covid-19 originated in fur farms, especially mink, as our investigation shows. (reporterre.net)
  • This is similar to mink as we saw in Mink farms in Denmark and the Netherlands . (reporterre.net)
  • Evaluation of a polyvalent foot-and-mouth disease virus vaccine containing A Saudi-95 against field challenge on large-scale dairy farms in Saudi Arabia with the emerging A/ASIA/G-VII viral lineage. (harvard.edu)
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. (genecards.org)
  • They are utilized to investigate genes in cell cultures of the proteins which are encoded by those genes via mass production method or manipulated as probable vectors to examine genes in the cells of patients for diagnosis and treatment of several genetic diseases and cancers. (wikipedia.org)
  • The diseases associated with M proteins are listed in Table 104-1. (wordpress.com)
  • An adenovirus vectored mucosal adjuvant augments protection of mice immunized intranasally with an adenovirus-vectored foot-and-mouth disease virus subunit vaccine. (harvard.edu)
  • Methods for treating cancer, viral diseases, respiratory. (google.es)
  • In conclusion, the immunomodulatory, antioxidant, and neuroprotective effects of melatonin suggest that this indole must be considered as an additional therapeutic alternative to fight viral diseases. (eattheapple.com)
  • Samples were placed in plastic bags, identified and stored in house freezers (−15°C) before delivery to the laboratory on ice for long-term storage at −80°C. In addition, carcasses of four free-ranging mink from the province of New Brunswick were tested. (biomedcentral.com)
  • The disease occurs in all color types, but mink which are homozygous recessive for the Aleutian gene for light coat color are particularly susceptible. (harvard.edu)
  • While Aleutian disease does not really cause any direct harm, it depresses the ferret's immune system in such a way, that the animal becomes susceptible to a number of other diseases. (pethealthandcare.com)
  • Back in the spring and early summer , mink farmers in the Netherlands reported coronavirus outbreaks in their animals, and this was followed by reports from Denmark and other countries in Europe. (sciencemag.org)
  • Utah fur ranches reported coronavirus outbreaks in their mink populations (with thousands of dead animals) in August . (sciencemag.org)
  • For "herd immunity" fans, the outbreaks seem to tail off once about 90% of the population has been exposed, but that's a lot higher number than you'd ever want to hit, and it's also worth noting that the human population is not well modeled by the conditions on a mink farm. (sciencemag.org)
  • The genome of Rabies virus, Borna disease virus and Ebola virus code for the P phosphoprotein and VP35 that can block the antiviral response induced by IFN [ 8 , 9 , 10 ]. (intechopen.com)
  • In the placentae of these mink, virus DNA and viral mRNA were detected in cells in the mesenchymal stroma of the placental labyrinth and hematoma but only occasionally in the cytotrophoblast of the placental hematoma. (dtu.dk)
  • Positive PCR or CIEP samples were detected in 56 of 60 (93.3%) American mink, 43 of 61 (70.5%) short-tailed weasels, 2 of 8 (25.0%) striped skunks, 2 of 11 (18.2%) North American river otters, 9 of 85 (10.6%) raccoons, and 2 of 20 (10.0%) bobcats. (biomedcentral.com)
  • The disease was so named because it was first found in mink with the Aleutian coat color gene, a gun-metal grey pelt. (wikipedia.org)
  • But the places to watch are Poland and China: these are big mink pelt producers, and (as far as I can see) nothing has been heard from them about this new problem. (sciencemag.org)
  • Japanese Patent Publication (Kohyo) 2 (1990) - 500880), it was found that hepatitis C is an infectious disease who causative agent is hepatitis C virus (HCV) that is transmitted through the blood and blood products as its main route of infection. (wipo.int)
  • Aleutian Mink Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • Positive CIEP or PCR animals were present in all nine counties from which mink or weasel samples were collected. (biomedcentral.com)
  • Laboratory of Immunoregulation (LIR) studies the regulation of the human immune system in health and disease, with emphasis on the immunopathogenic mechanisms of HIV infection and disease progression. (nih.gov)
  • Mechanisms allowing persistance of agents for long periods before producing disease are discussed. (annals.org)
  • To analyze the molecular mechanisms of cross-host transmission of the Aleutian mink disease vi rus (ADV), the hypervariable region fragment of the VP2 gene of the ADV in Jilin Province (China) was amplified. (bvsalud.org)
  • Parasites of farm minks and farm foxes in Iceland. (keldur.is)
  • Here we present a collection of articles published in Acta Veterinaria Scandinavica advancing our knowledge of wildlife research, ranging from diseases in reindeer to mountain goats to gulls to otters to moles. (biomedcentral.com)
  • It is an opportunistic pathogen and can induce chronic, persistent gastritis and ulcer formation similar to the disease in people. (merckvetmanual.com)
  • Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. (naver.com)
  • The Laboratory of Immune System Biology (LISB) is focused on the basic genetics, molecular biology, and cell biology of the immune system, as well as on human disease informed by these more basic studies. (nih.gov)
  • Our research focuses on emerging infectious diseases in human and animals. (helsinki.fi)
  • On both continents, it's believed that the disease spread from the human farm workers into the mink populations. (sciencemag.org)
  • Elle réunit des chercheurs ayant des compétences en dynamique des populations, en écologie évolutive, en éco-épidémiologie, en modélisation mathématique et en analyse statistique. (univ-lyon1.fr)
  • Examination of Aleutian disease virus in charge-shift crossed immunoelectrophoresis. (molecularstation.com)
  • The surface properties of Aleutian disease virus were studied by charge-shift crossed immunoelectrophoresis. (molecularstation.com)
  • Counter current line absorption immunoelectrophoresis is an alternative diagnostic screening test to counter current electrophoresis in Aleutian disease (AD) eradication programs. (thefreedictionary.com)
  • Solid signs and open signs represent Aleutian mink disease virus infected and non-infected species, respectively. (biomedcentral.com)
  • By contrast, animals bred for their fur, particularly the three main species - mink, fox, and the raccoon dog - are highly sensitive to it. (reporterre.net)
  • Bloom, M. E. / Replication of Aleutian mink disease parvorivus in lymphoid tissues of adult mink : Involvement of follicular dendritic cells and macrophages . (elsevier.com)
  • This virus can unfortunately reduce fitness of wild mink especially, by disturbing both the productivity within adult females and the overall survivor rates of both juveniles and adults. (wikipedia.org)
  • In mink kits, AD causes an acute cytopathic infection of alveolar cells, which leads to respiratory distress and death ( 8 ). (cdc.gov)
  • Acute interstitial pneumonitis caused by Aleutian disease virus in mink kits. (molecularstation.com)
  • Different mammals have different susceptibilities to the virus (to any virus), and it appears that Covid-19 is highly transmissible in mink. (sciencemag.org)
  • All transmissible diseases (PCR): Anaplasma, Babesia, Theileria. (vetlab.com.ua)
  • In the 1960s, it was common practice for mink ranchers to make their own distemper vaccines by homogenizing tissue from distemper-infected mink, making suspensions, and injecting all the mink on their ranch. (wikipedia.org)
  • In each city associations between particles with an aerodynamic diameter of less than 10 microm (PM(10)) and black smoke and daily counts of emergency hospital admissions for asthma (0-14 and 15-64 yr), chronic obstructive pulmonary disease (COPD), and all-respiratory disease (65+ yr) controlling for environmental factors and temporal patterns were investigated. (arctichealth.org)
  • This study confirms that particle concentrations in European cities are positively associated with increased numbers of admissions for respiratory diseases and that some of the variation in PM(10) effect estimates between cities can be explained by city characteristics. (arctichealth.org)
  • Use of animals in biomedical research is necessary to expand our ability to curtail infectious diseases, characterize new diseases, combat bioterrorism, and discover new ways to augment or harness the body's immune system. (nih.gov)
  • Diseases associated with this genus include progressive disorder of immune system. (wikipedia.org)
  • Role of the immune response in visna, a lentiviral central nervous system disease of sheep. (keldur.is)
  • The Serum Science Institute in Denmark seems to be the place where these effects were found, and they've shared their findings with the WHO and the European Centre for Disease Prevention and Control. (sciencemag.org)
  • This is a growing concern within mink producers as it is the most significant infectious disease affecting farmed mink worldwide. (wikipedia.org)
  • The invention also relates to methods for making such complexes and compositions comprising alpha (2) macroglobulin complexes, isolated from the serum of a mammal, wherein such compositions are used in methods for the treatment and prevention of cancer and infectious disease. (patents.com)
  • The invention also relates to methods for treating and preventing cancer and infectious disease using such complexes comprising, isolated from the serum of a mammal. (patents.com)
  • The remainder of this article discusses the disease-causing Parvoviridae . (wikipedia.org)