Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity. (1/10)
The seed oil derived from the tung (Aleurites fordii Hemsl.) tree contains approximately 80% alpha-eleostearic acid (18:3delta(9cis,11trans,13trans)), an unusual conjugated fatty acid that imparts industrially important drying qualities to tung oil. Here, we describe the cloning and functional analysis of two closely related Delta(12) oleate desaturase-like enzymes that constitute consecutive steps in the biosynthetic pathway of eleostearic acid. Polymerase chain reaction screening of a tung seed cDNA library using degenerate oligonucleotide primers resulted in identification of two desaturases, FAD2 and FADX, that shared 73% amino acid identity. Both enzymes were localized to the endoplasmic reticulum of tobacco (Nicotiana tabacum cv Bright-Yellow 2) cells, and reverse transcriptase-polymerase chain reaction revealed that FADX was expressed exclusively within developing tung seeds. Expression of the cDNAs encoding these enzymes in yeast (Saccharomyces cerevisiae) revealed that FAD2 converted oleic acid (18:1delta(9cis)) into linoleic acid (18:2delta(9cis,12cis)) and that FADX converted linoleic acid into alpha-eleostearic acid. Additional characterization revealed that FADX exhibited remarkable enzymatic plasticity, capable of generating a variety of alternative conjugated and delta(12)-desaturated fatty acid products in yeast cells cultured in the presence of exogenously supplied fatty acid substrates. Unlike other desaturases reported to date, the double bond introduced by FADX during fatty acid desaturation was in the trans, rather than cis, configuration. Phylogenetic analysis revealed that tung FADX is grouped with delta(12) fatty acid desaturases and hydroxylases rather than conjugases, which is consistent with its desaturase activity. Comparison of FADX and other lipid-modifying enzymes (desaturase, hydroxylase, epoxygenase, acetylenase, and conjugase) revealed several amino acid positions near the active site that may be important determinants of enzymatic activity. (+info)Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondria. (2/10)
Tail-anchored membrane proteins are a class of proteins that are targeted posttranslationally to various organelles and integrated by a single segment of hydrophobic amino acids located near the C terminus. Although the localization of tail-anchored proteins in specific subcellular compartments in plant cells is essential for their biological function, the molecular targeting signals responsible for sorting these proteins are not well defined. Here, we describe the biogenesis of four closely related tung (Aleurites fordii) cytochrome b5 isoforms (Cb5-A, -B, -C, and -D), which are small tail-anchored proteins that play an essential role in many cellular processes, including lipid biosynthesis. Using a combination of in vivo and in vitro assays, we show that Cb5-A, -B, and -C are targeted exclusively to the endoplasmic reticulum (ER), whereas Cb5-D is targeted specifically to mitochondrial outer membranes. Comprehensive mutational analyses of ER and mitochondrial Cb5s revealed that their C termini, including transmembrane domains (TMD) and tail regions, contained several unique physicochemical and sequence-specific characteristics that defined organelle-specific targeting motifs. Mitochondrial targeting of Cb5 was mediated by a combination of hydrophilic amino acids along one face of the TMD, an enrichment of branched beta-carbon-containing residues in the medial portion of the TMD, and a dibasic -R-R/K/H-x motif in the C-terminal tail. By contrast, ER targeting of Cb5 depended primarily upon the overall length and hydrophobicity of the TMD, although an -R/H-x-Y/F- motif in the tail was also a targeting determinant. Collectively, the results presented provide significant insight into the early biogenetic events required for entry of tail-anchored proteins into either the ER or mitochondrial targeting pathways. (+info)Benefits and side effects of different vegetable oil vectors on apoptosis, oxidative stress, and P2X7 cell death receptor activation. (3/10)
PURPOSE: Ocular side effects in patients using eye drops may be due to intolerance to the vector used in eye drops. Castor oil is the commonly used lipophilic vector but has been shown to be cytotoxic. Effects on cells of four oils (olive, camelina, Aleurites moluccana, maize) were compared with those of castor oil in human conjunctival cells. METHODS: Human conjunctival cells were incubated with the oils for 15 minutes. After a 24-hour recovery period, cells were tested for viability, proliferation, apoptosis (P2X7 cell death receptor and caspase 3 activation), intracellular redox potential, and reactive oxygen species production. Fatty acid incorporation in cell membranes was also analyzed. In vivo ocular irritation was assessed using the Draize test. RESULTS: Compared to the four other oils, castor oil was shown to induce significant necrosis and P2X7 cell death receptor and caspase 3 activation and to enhance intracellular reactive oxygen species production. Aleurites moluccana and camelina oils were not cytotoxic and increased cell membrane omega-3 fatty acid content. None of the five tested oils showed any in vivo ocular irritation. CONCLUSIONS: The results demonstrated that castor oil exerts cytotoxic effects on conjunctival cells. This cytotoxicity could explain the side effects observed in some patients using eye drops containing castor oil as a vehicle. The lack of cytotoxic effects observed with the four other oils, Aleurites, camelina, maize, and olive, suggest that they could be chosen to replace castor oil in ophthalmic formulations. (+info)Tool use by wild New Caledonian crows Corvus moneduloides at natural foraging sites. (4/10)
(+info)The ecological significance of tool use in New Caledonian crows. (5/10)
(+info)The N termini of Brassica and tung omega-3 fatty acid desaturases mediate proteasome-dependent protein degradation in plant cells. (6/10)
The regulation of fatty acid desaturase activity in plants is important for determining the polyunsaturated fatty acid content of cellular membranes, which is often rapidly adjusted in plant cells in response to temperature change. Recent studies have demonstrated that the endoplasmic reticulum (ER)-localized omega-3 desaturases (Fad3s) are regulated extensively at the post-transcriptional level by both temperature-dependent changes in translational efficiency, as well as modulation of protein half-life. While the N-terminal sequences of Fad3 proteins were shown to contain information that mediates their rapid, proteasome-dependent protein turnover in both plant and yeast cells, it is currently unknown whether these sequences alone are sufficient to direct protein degradation. In this report, we fused the N-terminal sequences of two different Fad3 proteins to an ER-localized fluorescent protein reporter, consisting of the green fluorescent protein and the ER integral membrane protein cytochrome b5, and then measured (via microscopy) the degradation of the resulting fusion proteins in plant suspension-cultured cells relative to a second, co-expressed fluorescent reporter protein. Overall, the results demonstrate that the N-termini of both Fad3 proteins are sufficient for conferring rapid, proteasome-dependent degradation to an ER-bound marker protein. (+info)Expression of tung tree diacylglycerol acyltransferase 1 in E. coli. (7/10)
(+info)Antinociceptive, anti-inflammatory and wound healing features in animal models treated with a semisolid herbal medicine based on Aleurites moluccana L. Willd. Euforbiaceae standardized leaf extract: semisolid herbal. (8/10)
(+info)Aleurites moluccana (F160) :: Swingle Plant Anatomy Digital Archive
Selection of tool diameter by New Caledonian crows Corvus moneduloides. - Oxford Neuroscience
Contribution of α,β-Amyrenone to the Anti-Inflammatory and Antihypersensitivity Effects of Aleurites moluccana (L.) Willd.
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Endothelial dysfunction in Type 2 diabetes correlates with deregulated expression of the tail-anchored membrane protein SLMAP<...
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Structural Basis for Tail-Anchored Membrane Protein Biogenesis by the Get3-Receptor Complex
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Roger Tung | Concert Pharmaceuticals, Inc | Email CEO @concertpharma.com CFO
Office of Research - University of Michigan Medical School
A functional polymorphism in the CD95 cell death receptor associated with prognosis in acute promyelocytic leukemia [Abstract] ...
Intra- und postoperative Zwischenfälle: Ihre Verhütung und Behandling. | Annals of Internal Medicine | American College of...
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Aleurites
Media related to Aleurites at Wikimedia Commons Data related to Aleurites at Wikispecies (Wikipedia articles incorporating a ... 1911). "Aleurites" . Encyclopædia Britannica. Vol. 1 (11th ed.). Cambridge University Press. p. 543. "Aleurites moluccanus". ... Aleurites is a small genus of arborescent flowering plants in the Euphorbiaceae, first described as a genus in 1776. It is ... The name Aleurites is derived from the Ancient Greek: ἄλευρον meaning "wheaten flour" or "ground meal", because of the ...
Aleurites rockinghamensis
"Aleurites rockinghamensis (Baill.) P.I.Forst". Australian Plant Name Index (APNI), IBIS database. Centre for Plant Biodiversity ... Aleurites rockinghamensis, the candlenut, is a flowering tree in the spurge family, Euphorbiaceae found in northeastern ...
Aleurites moluccanus
"Aleurites moluccana". African plants - a Photo Guide. Frankfurt/Main: Forschungsinstitut Senckenberg. Aleurites moluccana usage ... Aleurites moluccanus, the candlenut, is a flowering tree in the spurge family, Euphorbiaceae, also known as candleberry, Indian ... It was renamed as Aleurites moluccana in 1805 by Carl Ludwig Willdenow in a later edition of Species Plantarum (Sp. Pl. 4: 590 ... While there are many online references to the name "Aleurites moluccana", this is not a name that is accepted by botanic ...
List of honey plants
Aleurites fordii Hemsl. Croton floribundus Spreng. Croton macrobothrys Baill. Croton salutaris Casar. Dalechampia humilis Müll. ...
Imshaugia
... aleurites (Ach.) S.L.F.Mey. (1985) Imshaugia angustior (Nyl.) Sipman (2021) Imshaugia evernica (Elix & J.Johnst.) ... In a previous study of Parmeliopsis, Meyer noted a group of species (represented by P. aleurites and P. placorodia) that would ... The phycobiont in Imshaugia is green algae - Trebouxia in I. aleurites, and Myrmecia in I. placorodia. The thallus contains ... Imshaugia aleurites, is widely distributed in northern North America, having been recorded from the tree line in the Arctic ...
List of lichens of Maryland
Lendemer & Knapp (2007) - (4. Sharptown) Imshaugia aleurites (Ach.) S.F. Meyer [Parmeliaceae] Syn.: Parmeliopsis aleurites (Ach ...
Vernicia fordii
"Aleurites fordii Hemsl". Handbook of Energy Crops. Purdue University. 1997. Fairchild, David (1938). The World Was My Garden: ... doi:10.1016/S0031-9422(00)98005-1. Media related to Vernicia fordii at Wikimedia Commons "Aleurites fordii (Hemsl.) Airy Shaw ... Apogee Components Condor: Glider using tung wood "Aleurites fordii". Florida Invasive Plant Education. University of Florida. ... Extracts of Aleurites fordii and its Diterpene Ester 12-O-Hexadecanoyl-16-hydroxyphorbol-13-acetate". Cancer Letters. 18 (1): ...
Jatropha
Aleurites moluccanus (L.) Willd. (as J. moluccana L.) Baliospermum montanum (Willd.) Müll.Arg. (as J. montana Willd.) ...
Lake Euramoo
Aleurites moluccana, Macaranga spp.) Myrtaceae (e.g. Austromyrtus spp., Eugenia cormiflora) and Rubiaceae (e.g. Flindersia ...
Hypomecis transcissa
Host plants include Aleurites species. "Species Details: Hypomecis transcissa Walker, 1860". Catalogue of Life. Retrieved 17 ...
Xylinophylla hypocausta
The larvae feed on Aleurites moluccanus. Holloway, Jeremy Daniel. "Xylinophylla hypocausta Warren stat. rev". The Moths of ...
Coumarinolignoid
... found in Aleurites moluccanus Aleuritin, found in Aleurites fordii Durantin A and repenins, isolated from Duranta Ma, Zhongjun ... a coumarinolignoid from Aleurites moluccana". Phytochemistry. 27 (6): 1908. doi:10.1016/0031-9422(88)80480-1. Fozdar, B.I.; ... and a coumarin from Aleurites fordii". Phytochemistry. 28 (9): 2459. doi:10.1016/S0031-9422(00)98005-1. v t e ( ...
Candlenut oil
... or kukui nut oil is extracted from the nut of Aleurites moluccanus (Aleurites triloba), the candlenut or kuku'i. ... the oil of Aleurites cordata (now V. cordata) yields "Japanese tung oil". Thompson, Alice R. (1913), "Kukui (Candle-Nut) Oil", ... Aleurites, Triloba, Oil of., p.1556 Mindaryani, A.; Rahayu, S. S. (2010). "Epoxidation of candlenut oil". 2010 International ...
List of Stachys species
Stachys albotomentosa Ramamoorthy Stachys aleurites Boiss. & Heldr. Stachys alpigena T.C.E.Fr. Stachys alpina L. Stachys ...
List of Euphorbiaceae of South Africa
indigenous Genus Aleurites: Aleurites moluccana (L.) Willd. not indigenous, naturalised Aleurites moluccana (L.) Willd. var. ...
List of lichens of Soldiers Delight
8 January 1984) L-467 Imshaugia aleurites (Ach.) S.F. Meyer [EGW] Collected and identified by B. Ball and A. Norden; on scrub ... often grows with Imshaugia aleurites and Ahtiana aurescens. (9 March 1980) L-269 [EGW] Collected and identified by EGW; on bark ...
Conactiodoria
... aleurites Townsend, 1940 Conactiodoria aurea Townsend, 1934 Brazil. Townsend, C.H.T. (1934). "New Neotropical ...
Aleuritin
... is a coumarinolignoid found in the tree Aleurites fordii. Fozdar, B. I.; Khan, S. A.; Shamsuddin, T.; Shamsuddin, K. ... M.; Kintzinger, J. (1989). "Aleuritin, a Coumarinolignoid, and a Coumarin from Aleurites fordii". Phytochemistry. 28 (9): 2459- ...
Paleobiota of the London Clay
Urticaceae †Urticicarpum scutellum Euphorbiaceae - the spurge family Aleurites sp. Croton sp. Euphorbia sp. - similar to ...
List of culinary nuts
Candlenut (Aleurites moluccana), used in many South East Asian cuisines. Chestnuts (Castanea spp.) Chinese chestnuts (Castanea ...
Oxydema fusiforme
The other host plants include, Aleurites moluccana and Pandanus odorifer. It is also an intermediate host of the nematode, ...
Coconut crab
Aleurites moluccanus), drupes (Cocos nucifera) and seeds (Annona reticulata); and the pith of fallen trees. However, as they ...
Vernicia
The species have often been included within the related genus Aleurites. They are shrubs or trees growing to 20 m tall. The ...
Lumban
It got its name from Aleurites moluccanus, a tree locally named "lumbang". The province's capital town, Santa Cruz, as well as ...
Ascocoryne sarcoides
In Hawaii, it grows on trunks of fallen Cibotium and Aleurites trees. A. sarcoides occurs most frequently in late summer and ...
Flueggea neowawraea
Aleurites moluccanus), hame (Antidesma pulvinatum), ʻahakea (Bobea sp.), alaheʻe (Psydrax odorata), olopua (Nestegis ...
Dili
... and Aleurites moluccana. Eucalyptus alba is found in rocky areas, and palm and acacia trees are also found. The eucalyptus ...
Maurice Langeron
Le genre Aleurites Forst (Euphorbiacées) systématique, anatomie, pharmacologie, 1902 - The genus Aleurites (Euphorbiaceae); ...
Alloxylon flammeum
Here Alloxylon flammeum is found with such species as candlenut (Aleurites rockinghamensis), Argyrodendron spp., fishtail ...
Timor
Typical trees of the lowland slopes include Sterculia foetida, Calophyllum teysmannii and Aleurites moluccanus. During the ...
Aleurites moluccana (L.) Willd. | Europeana
Aleurites moluccana - Plants of Hawaii - Starr Environmental
Aleurites - eFlora of India
1. For any mistake in identification or for becoming efloraofindia e-group member (for contributing towards building of efloraofindia or otherwise), pl. mail to [email protected] or [email protected] 2. For better viewing of species pages, colour scheme & formatting is being followed as: Description of the species, Details of other flora species on the same page, Uses/ harms, Distribution, Abundance/ Location/ Flowering time & date, Habit & habitat, Etymology & pronunciation, Other interesting information, stories etc., Others, Botanical names, Common names, Main point of discussion below, Discussion about Botanical names.. ...
Aleurites moluccanus var. floccosus Airy Shaw | Plants of the World Online | Kew Science
Aleurites moluccanus var. floccosus Airy Shaw. This is a synonym of Aleurites moluccanus (L.) Willd. ... Aleurites moluccanus var. floccosus Airy Shaw appears in other Kew resources:. IPNI - The International Plant Names Index. ... Cited as Aleurites moluccana.]. *Govaerts, R., Frodin, D.G. & Radcliffe-Smith, A. (2000). World Checklist and Bibliography of ...
buy Aleurites moluccana plant | Plantslive
APII database extract: photo class = 'dig' and photo no = '3743'
Aleurites Moluccana (Kukui) Seed Oil ingredient | Aveda
Pages that link to "Aleurites moluccanus (PROTA)" - PlantUse English
Sell Aleurites Moluccana Seed Oil 100ml | Cipta Anugerah Bakti Mandiri Surabaya
Nuez de la India 12 seeds from 8,33 EUR, Aleurites Moluccana, 9,99 €
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Plant Characters Determinant that Influence The Yield of Candlenut [Aleurites moluccana (L.) Willd.] | Tresniawati | Jurnal...
The Effect of Candlenut (Aleurites Moluccana I Willd.) Seed Flour in Native Chicken Feeding Toward the Internal Egg Quality...
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Aleurites moluccanus (L.) Willd.. Accepted. WCSP. 2012-03-23. Aleurites moluccanus var. aulanii O.Deg. & I.Deg.. Synonym. WCSP ... Aleurites cordata R. Br. ex Steud.. Unresolved. TRO. 2012-04-18. Aleurites cordatus (Thunb.) R.Br. ex Steud.. Synonym. WCSP. ... Aleurites moluccanus var. remyi (Sherff) Stone. Synonym. WCSP. 2012-03-23. Aleurites moluccanus var. rockinghamensis Baill.. ... Aleurites saponarius Blanco. Synonym. WCSP. 2012-03-23. Aleurites triloba J.R. Forst. & G. Forst.. Unresolved. TRO. 2012-04-18 ...
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Kukui Nut1
- Kukui Nut oil (Aleurites Moluccans) was discovered by native Hawaiians many centuries ago. (jenulence.com)
Willd1
- Tumbuhan kemiri (Aleurites Moluccana (L.) Willd banyak dimanfaatkan oleh manusia terutama pada bagian bijinya. (unej.ac.id)
Fordii1
- Here we describe the biogenesis of four closely related tung (Aleurites fordii) cytochrome b5 isoforms (Cb5-A, -B, -C, and -D), which are small tail-anchored proteins that play an essential role in many cellular processes, including lipid biosynthesis. (usda.gov)
Candlenut1
- The most widespread and well known species in the candlenut , Aleurites moluccana , the state tree of Hawaii. (allthingsnature.org)
Moluccana Seed1
- Aleurites Moluccana Seed Extract is an extract of the nuts of the kukui, Aleurites moluccana. (ewg.org)
Genus1
- Aleurites is a genus of flowering evergreen trees native to tropical and subtropical areas of South America, Asia, and the Pacific Islands. (allthingsnature.org)
Cordata1
- Aleurites cordata auct. (altervista.org)
Triloba1
- Aleurites triloba J.R. Forst. (itis.gov)
Seeds1
- From Asia, the Kukui nut is pressed from the seeds of the Aleurites Moluccana Tree, which oil contains Omega-6 and Omega-3, two essential fatty acids which cannot be produced by the human body. (cozmetica.pk)
Tree1
- The kukui (Aleurites moluccana) is a tree that has stood by the side of Polynesian peoples for thousands of years and is one of the foundations of their cultures. (mnbg.org)
Common1
- Aleurites moluccana gets its common name from the fact that the seed can be used as a candle due to its rich oil content. (allthingsnature.org)
Native1
- Aleurites are native to tropical and sub-tropical regions. (allthingsnature.org)
Cooking oil1
- Aleurites oil can also be used as cooking oil if it is treated to remove poisonous elements. (allthingsnature.org)
Moluccanus4
- Also known as Aleurites moluccanus. (starrenvironmental.com)
- Aleurites moluccanus var. (kew.org)
- Kukui oil comes from Hawaii and is produced by cold-pressing the seeds of the Aleurites Moluccanus tree, a treasured natural source of seed oil. (kikocosmetics.com)
- All the Kukui ( Aleurites moluccanus) half shells have been gathered by Kumu Kaponoʻai and his ʻohana on the island of Maui in the uplands of ʻĪao to the shores of Honokahua. (native-intel.com)
Fordi Oil Copolymer1
- Triisostearate Polybutene Brassica Camp - estris / Aleurites Fordi Oil Copolymer Synthetic Fluorphlogopite Ceresin Calcium Aluminum Borosilicate Titanium Dioxide (CI 77891) Octyldodecanol Ricinus Communis (Castor) Seed Oil Ozokerite Oleyl Alcohol Diisostearyl Malate Isoamyl p - Methoxy- cinnamate Isohexadecane Bis-PEG-/PPG14/14. (mirenesse.com)
Brassica Campestris2
- Brassica Campestris/Aleurites Fordi is a biodegradable, botanical based high performance polymer made from tung (China wood) and rapeseed oils. (lovinah.com)
- Brassica Campestris/Aleurites Fordi has the power to stay on skin longer, delivering superior protection from damage caused by aging pollutants and environmental aggressors. (lovinah.com)
SEED OIL4
- Aleurites Moluccana (Kukui Nut) Oil, Rubus Idaeus (Raspberry) Seed Oil, Cucumber Hydrosols, Calophyllum Inophyllum (Tamanu) Oil. (nordstrom.com)
- Argania Spinosa (Argan) Kernel Oil*, Crambe Abyssinica (Abyssinian) Seed Oil, Aleurites Moluccana (Kukui) Seed Oil, Tocopherol *Ingredient from Organic Farming. (mankind.co.uk)
- Citrus & Lavender luxury body oil: Ingredients: Prunus Amygdalus Dulcis (Sweet Almond) Oil, Persea Gratissima (Avocado) Oil, Aleurites Moluncanus seed oil, Lavandula Angustifolia (Lavender) flower Oil, Citrus Grandis (Grapefruit) Essential Oil. (heylandandwhittle.co.uk)
- Ingredients: Helianthus Annuus (Sunflower) Seed Oil*, Cocos Nucifera (Coconut) Oil*, Cera Alba (Beeswax)*, Butyrospermum Parkii (Shea Butter)*, Theobroma Cacao (Cocoa) Seed Butter*, Prunus Amygdalus Dulcis (Sweet Almond) Oil*, Canola Oil*, Aleurites Moluccana (Kukui) Seed Oil*, Hippophae Rhamnoides (Sea Buckthorn) Oil*, Tocopherol (Non-GMO). (27sextoys.com)
Airy Shaw1
- Airy Shaw (Aleurites cordata (Thunb. (mfa.org)
Moluccans1
- Kukui Nut oil (Aleurites Moluccans) was discovered by native Hawaiians many centuries ago. (jenulence.com)
Species1
- Species Identification Sheet Common name: Kukui nut tree Scientific name: Aleurites moluccana Geographic area of origin: Indo Malaysia Common uses/hazards/importance: It can be used for cooking, lighting places, medicine, jewelry, tattoos, and fisherman could use it to break the surface tension in the water to remove the reflections and increase their visibility range. (projectnoah.org)
Thunb1
- Aleurites cordatus (Thunb. (theplantlist.org)
Forst1
- Aleurites triloba J.R. Forst. (theplantlist.org)
Nuts1
- Kukui Butter is obtained from the dried nuts of the Kukui tree (Aleurites moluccana) by cold pressing and subsequent refining. (cosmeticsandtoiletries.com)
Plant1
- 39 plant name records match your search criteria Aleurites . (theplantlist.org)