Aldicarb: Carbamate derivative used as an insecticide, acaricide, and nematocide.Thiocholine: A mercaptocholine used as a reagent for the determination of CHOLINESTERASES. It also serves as a highly selective nerve stain.Ictaluridae: A family of North American freshwater CATFISHES. It consists of four genera (Ameiurus, Ictalurus, Noturus, Pylodictis,) comprising several species, two of which are eyeless.Insecticides: Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.Cholinesterase Inhibitors: Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.CholinesterasesToxicity Tests, Acute: Experiments designed to determine the potential toxic effects of one-time, short-term exposure to a chemical or chemicals.Cholinesterase Reactivators: Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates.Gills: Paired respiratory organs of fishes and some amphibians that are analogous to lungs. They are richly supplied with blood vessels by which oxygen and carbon dioxide are exchanged directly with the environment.Sulfoxides: Organic compounds that have the general formula R-SO-R. They are obtained by oxidation of mercaptans (analogous to the ketones). (From Hackh's Chemical Dictionary, 4th ed)Lethal Dose 50: The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.Acetylcholinesterase: An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.Water Pollution, Chemical: Adverse effect upon bodies of water (LAKES; RIVERS; seas; groundwater etc.) caused by CHEMICAL WATER POLLUTANTS.Oncorhynchus mykiss: A large stout-bodied, sometimes anadromous, TROUT found in still and flowing waters of the Pacific coast from southern California to Alaska. It has a greenish back, a whitish belly, and pink, red, or lavender stripes on the sides, with usually a sprinkling of black dots. It is highly regarded as a sport and food fish. Its former name was Salmo gairdneri. The sea-run rainbow trouts are often called steelheads. Redband trouts refer to interior populations of rainbows.Bass: Common name for FISHES belonging to the order Perciformes and occurring in three different families.

A neomorphic syntaxin mutation blocks volatile-anesthetic action in Caenorhabditis elegans. (1/53)

The molecular mechanisms underlying general anesthesia are unknown. For volatile general anesthetics (VAs), indirect evidence for both lipid and protein targets has been found. However, no in vivo data have implicated clearly any particular lipid or protein in the control of sensitivity to clinical concentrations of VAs. Genetics provides one approach toward identifying these mechanisms, but genes strongly regulating sensitivity to clinical concentrations of VAs have not been identified. By screening existing mutants of the nematode Caenorhabditis elegans, we found that a mutation in the neuronal syntaxin gene dominantly conferred resistance to the VAs isoflurane and halothane. By contrast, other mutations in syntaxin and in the syntaxin-binding proteins synaptobrevin and SNAP-25 produced VA hypersensitivity. The syntaxin allelic variation was striking, particularly for isoflurane, where a 33-fold range of sensitivities was seen. Both the resistant and hypersensitive mutations decrease synaptic transmission; thus, the indirect effect of reducing neurotransmission does not explain the VA resistance. As assessed by pharmacological criteria, halothane and isoflurane themselves reduced cholinergic transmission, and the presynaptic anesthetic effect was blocked by the resistant syntaxin mutation. A single gene mutation conferring high-level resistance to VAs is inconsistent with nonspecific membrane-perturbation theories of anesthesia. The genetic and pharmacological data suggest that the resistant syntaxin mutant directly blocks VA binding to or efficacy against presynaptic targets that mediate anesthetic behavioral effects. Syntaxin and syntaxin-binding proteins are candidate anesthetic targets.  (+info)

Aldicarb as a cause of food poisoning--Louisiana, 1998. (2/53)

Cholinesterase-inhibiting pesticides (i.e., organic phosphates and carbamates), widely used in agriculture, can cause illness if they contaminate food or drinking water. Aldicarb, a regulated carbamate pesticide, is highly toxic, and the U.S. Environmental Protection Agency (EPA) requires applicators to be trained and certified. This report describes a foodborne outbreak of aldicarb poisoning that occurred when improperly stored and labeled aldicarb was used mistakenly in food preparation.  (+info)

In vitro sulfoxidation of aldicarb by hepatic microsomes of channel catfish, Ictalurus punctatus. (3/53)

The carbamate pesticide, aldicarb, demonstrates significant acute toxicity in mammals, birds, and fish, and is readily biotransformed by most organisms studied. Metabolic products of aldicarb include the more toxic sulfoxide and the less toxic sulfone as two of the major products. Both the cytochrome P450 (CYP) and the flavin monooxygenase systems (FMO) are involved in this process. This study examined the capacities of liver microsomes of male channel catfish (Ictalurus punctatus), which lack FMO, to biotransform aldicarb in vitro. In addition, the acetylcholinesterase inhibitory potencies of aldicarb and its sulfoxide and sulfone derivatives were determined. For metabolism studies, incubations of [14C]-aldicarb (0.1mM) were carried out for up to 15-90 min using 1.0 mg/mL of hepatic microsomal protein. Total NADPH- dependent biotransformation was low (< 3.0% conversion to polar metabolites), and was inhibited by carbon monoxide. The only metabolite detected was aldicarb sulfoxide (Kmapp = 53.8 +/- 25.3 microM; Vmaxapp = 0.040 +/- 0.007 nmol/min/mg). Treatment of fish with the CYP modulators beta-naphthoflavone (BNF, 50 mg/kg) and ethanol (EtOH, 1.0% aqueous) had no effect on sulfoxide production. No correlation existed between CYP isoform expression (determined by western blot) and aldicarb sulfoxidation rates, suggesting the involvement of an unmeasured CYP isoform or involvement of several isoforms with low specificity. This study indicates that a low rate of bioactivation of aldicarb to aldicarb sulfoxide may be responsible for the resistance of channel catfish to aldicarb toxicity relative to that of other piscine species.  (+info)

A case of aldicarb poisoning: a possible murder attempt. (4/53)

A couple showing signs of cholinergic crisis was admitted to the hospital. Analyses with high-performance liquid chromatography and gas chromatography-mass spectrometry conducted on serum, urine, and stomach contents that were collected few hours after first symptoms showed the presence of aldicarb, which is the most potent carbamate insecticide on the market. A murder attempt was suspected because the patients showed the first signs some minutes after drinking coffee upon returning home and no commercial products containing aldicarb were found in the house. Because of the reversibility of inhibition of acetylcholinesterase, the patients recovered after treatment with atropine and toxogonin. They left the hospital after 12 days. To our knowledge, the serum concentrations of aldicarb reported in this paper are the highest reported for a nonfatal case.  (+info)

Serotonin inhibition of synaptic transmission: Galpha(0) decreases the abundance of UNC-13 at release sites. (5/53)

We show that serotonin inhibits synaptic transmission at C. elegans neuromuscular junctions, and we describe a signaling pathway that mediates this effect. Release of acetylcholine from motor neurons was assayed by measuring the sensitivity of intact animals to the acetylcholinesterase inhibitor aldicarb. By this assay, exogenous serotonin inhibited acetylcholine release, whereas serotonin antagonists stimulated release. The effects of serotonin on synaptic transmission were mediated by GOA-1 (a Galpha0 subunit) and DGK-1 (a diacylglycerol [DAG] kinase), both of which act in the ventral cord motor neurons. Mutants lacking goa-1 G(alpha)0 accumulated abnormally high levels of the DAG-binding protein UNC-13 at motor neuron nerve terminals, suggesting that serotonin inhibits synaptic transmission by decreasing the abundance of UNC-13 at release sites.  (+info)

In vivo acetylcholinesterase inhibition, metabolism, and toxicokinetics of aldicarb in channel catfish: role of biotransformation in acute toxicity. (6/53)

The carbamate pesticide, aldicarb, demonstrates significant acute toxicity in mammals, birds, and fish through the inhibition of acetylcholinesterase (AChE), and may present high potential for exposure of aquatic organisms during periods of runoff. Toxicity studies have shown that channel catfish are less sensitive to the acute toxic effects of aldicarb than are rainbow trout or bluegill. An earlier in vitro study suggests that the aldicarb resistance in catfish may be related to a low level of bioactivation to the potent aldicarb sulfoxide. The current study examines the toxicity, AChE inhibition, plasma kinetics, and in vivo metabolism of aldicarb in channel catfish. A 48-h LC50 of 9.7 mg/l was determined for juvenile channel catfish. Mortality was accompanied by dramatic loss of brain AChE. Further characterization of tissue-level effects suggests that muscle AChE plays a causal role in mortality. Aldicarb was metabolized in channel catfish to aldicarb sulfoxide, along with the formation of minor hydrolytic products. The toxicokinetics of aldicarb in catfish are bi-compartmental with rapid elimination (t1/2 = 1.9 h). Plasma AChE was inhibited in a pattern similar to that of the elimination of total aldicarb-derived compounds. A comparison of aldicarb uptake between catfish and rainbow trout showed no difference in compound absorbed in 24 h. The pattern of in vivo metabolism, however, was quite different between these species. Rainbow trout produce significantly more hydrolytic derivatives and have a 3-fold higher aldicarb sulfoxide to aldicarb ratio at 3 h. These data give strength to the hypothesis that a slower rate of bioactivation in the catfish (vs. rainbow trout) is acting as a protective mechanism against the acute toxicity of aldicarb.  (+info)

Mitochondrial expression and function of GAS-1 in Caenorhabditis elegans. (7/53)

A mutation in the gene gas-1 alters sensitivity to volatile anesthetics, fecundity, and life span in the nematode Caenorhabditis elegans. gas-1 encodes a close homologue of the 49-kDa iron protein subunit of Complex I of the mitochondrial electron transport chain from bovine heart. gas-1 is widely expressed in the nematode neuromuscular system and in a subcellular pattern consistent with that of a mitochondrial protein. Pharmacological studies indicate that gas-1 functions partially via presynaptic effects. In addition, a mutation in the gas-1 gene profoundly decreases Complex I-dependent metabolism in mitochondria as measured by rates of both oxidative phosphorylation and electron transport. An increase in Complex II-dependent metabolism also is seen in mitochondria from gas-1 animals. There is no apparent alteration in physical structure in mitochondria from gas-1 nematodes compared with those from wild type. These data indicate that gas-1 is the major 49-kDa protein of complex I and that the GAS-1 protein is critical to mitochondrial function in C. elegans. They also reveal the importance of mitochondrial function in determining not only aging and life span, but also anesthetic sensitivity, in this model organism.  (+info)

Effects of salinity on aldicarb toxicity in juvenile rainbow trout (Oncorhynchus mykiss) and striped bass (Morone saxatilis x chrysops). (8/53)

Fluctuations in several environmental variables, such as salinity, can influence the interactions between organisms and pollutants in aquatic organisms, and, therefore, affect the toxicity of xenobiotics. In this study, after 2 species of fish, rainbow trout (Oncorhynchus mykiss) and hybrid striped bass (Morone saxatilis x chrysops) were acclimated to 4 salinity regimens of 1.5, 7, 14, and 21 ppt for 1 week and then exposed to 0.5 mg/l aldicarb. Mortality, brain, and muscle cholinesterase levels were measured after 96 h. Rates of (14)C-aldicarb sulfoxide formation were determined in kidney (trout only), liver, and gill microsomes from each species acclimated to the 4 salinity regimens. Salinity significantly enhanced aldicarb toxicity, cholinesterase inhibition, and (14)C-aldicarb sulfoxide formation in rainbow trout but not in striped bass. In vitro incubations with (14)C-aldicarb and the cytochrome P450 (CYP) inhibitor, N-benzylimidazole, did not significantly alter aldicarb sulfoxide formation in tissue microsomes from either species of fish, indicating CYP did not contribute to aldicarb sulfoxidation. Salinity increased flavin-containing monooxygenase (FMO) mRNA expression and catalytic activities in microsomes of liver, gill, and kidney of rainbow trout, which was consistent with the salinity-induced enhancement of aldicarb toxicity. Salinity did not alter FMO mRNA expression and catalytic activities in striped bass, which was also consistent with the lack of an effect of salinity on aldicarb toxicity in this species. These results suggest that salinity-mediated enhancement of aldicarb toxicity is species-dependent, and at least partially due to the salinity-related upregulation of FMOs, which, in turn, increases the bioactivation of aldicarb to aldicarb sulfoxide, which is a more potent inhibitor of cholinesterase than aldicarb.  (+info)

*Aldicarb

... is one of the most widely used pesticides internationally, and is also one of the most environmentally toxic. Aldicarb ... A new aldicarb pesticide named AgLogic 15G, was approved by the EPA in December 2011 and is said to be entering the market in ... Aldicarb is a carbamate insecticide which is the active substance in the pesticide Temik. It is effective against thrips, ... Aldicarb is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. In case of severe ...

*Nematicide

Aldicarb is a cholinesterase inhibitor, which prevents the breakdown of acetylcholine in the synapse. In case of severe ... Aldicarb (Temik), a carbamate insecticide marketed by Bayer CropScience, is an example of a commonly used commercial nematicide ... "Bayer CropScience plans to discontinue Aldicarb by 2014". Retrieved 2012-09-01. D. J. Chitwood, "Nematicides," in Encyclopedia ... Bayer CropScience announced that it planned to discontinue aldicarb by 2014. Human health safety and environmental concerns ...

*Carbamic acid

... for example aldicarb. Carbamoyl phosphate M03BA Carbamic acid esters Thomas L. Lemke. (2003). Review of organic functional ... "The toxicologic effects of the carbamate insecticide aldicarb in mammals: a review". Environmental Health Perspectives. 72: 267 ...

*Carbamate

Included in this group are aldicarb (Temik), carbofuran (Furadan), carbaryl (Sevin), ethienocarb, fenobucarb, oxamyl, and ... the most potent compounds such as aldicarb and carbofuran are still capable of inhibiting mammalian acetylcholinesterase ...

*Quality Assurance International

Lynn Goldman, Johns Hopkins University's School of Public Health:] 'Ginger with Aldicarb is not legal food.' In fact, the ... was found when tested to be contaminated with the banned pesticide Aldicarb. The organic ginger from which the QAI certified ...

*Acute inhalation injury

... and aldicarb). It has also been used in the production of rubbers and adhesives. As a highly toxic and irritating material, it ...

*Methyl isocyanate

... and aldicarb). It has also been used in the production of rubbers and adhesives. As a highly toxic and irritating material, it ...

*Carbofuran

... only aldicarb and parathion are more toxic).[citation needed] Most carbofuran is applied by commercial applicators using closed ...

*Orange (fruit)

Soil application of aldicarb provided limited control of Asian citrus psyllid, while drenches of imidacloprid to young trees ...

*Organic cotton

... and aldicarb. Other pesticides persisting in cotton fields in the United States include Trifluralin, Toxaphene and DDT. ...

*Tobacco rattle virus

... and carmabates such as aldicarb and oxamyl are recommended as a last resort. Tobacco Rattle Virus is only found in nature in ...

*Carbamoyl chloride

... carbofuran and aldicarb. Carbamoyl chlorides are prepared by the reaction of an amine with phosgene: 2 R2NH + COCl2 → R2NCOCl ...

*Pratylenchus brachyurus

The plots in this study by Koenning were treated with aldicarb, carbofuran, and fenamiphos and had less nematodes 40 days post ...

*Meloidogyne arenaria

... on peanut has traditionally relied primarily on treatment of infested fields with nematicides such as granular aldicarb (Temik ...

*List of extremely hazardous substances

Acetone cyanohydrin Acetone thiosemicarbazide Acrolein Acrylamide Acrylonitrile Acryloyl chloride Adiponitrile Aldicarb Aldrin ...

*Agriculture in Thailand

Aldicarb, Azinphos-methyl, Chlorpyrifos-ethyl, Methoxychlor, and Paraquat. Instead, by 2014 the number of active ingredients in ...

*List of IARC Group 3 carcinogens

... chloride Acrolein Acrylic acid Acrylic fibres Acrylonitrile-butadiene-styrene copolymers Actinomycin D Agaritine Aldicarb ...

*Health in Thailand

Aldicarb, Azinphos-methyl, Chlorpyrifos-ethyl, Methoxychlor and Paraquat. A study by the health ministry and Britain's Wellcome ...

*List of MeSH codes (D02)

... aldicarb MeSH D02.241.081.251.125 --- benomyl MeSH D02.241.081.251.140 --- carbadox MeSH D02.241.081.251.145 --- carbamyl ...

*Emergency Planning and Community Right-to-Know Act

500 gallons of aldicarb oxime and highly toxic MIC leaked from the Institute plant. Although no one was killed, 134 people ...

*Dieldrin

The Stockholm Convention banned 12 POPs, nicknamed "the dirty dozen". These include: aldicarb, toxaphene, chlordane and ...

*Acetylcholinesterase inhibitor

Sarin Soman Tabun VX VE VG VM Diazinon Malathion Parathion Carbamates Aldicarb Bendiocarb Bufencarb Carbaryl Carbendazim ...

*Rotterdam Convention

2,4,5-T and its salts and esters Alachlor Aldicarb Aldrin Asbestos - Actinolite, Anthophyllite, Amosite, Crocidolite, and ...

*Food safety incidents in China

... but when tested was found to contain the banned pesticide Aldicarb. The ginger had been mistakenly certified organic by Quality ...

*Scutellonema bradys

Four granular nematicides (aldicarb, oxamyl, carbofuran and miral) applied as post-plant sidedressing treatments effectively ...
Kok FN, Arica MY, Halicigil C, Alaeddinoglu G, Hasirci V Carboxymethylcellulose microspheres cross-linked via aluminum ions were used as a support material for immobilization of Methylosinus isolated from soil contaminated with aldicarb. The degradation capacity of immobilized bacteria, different parameters such as substrate concentration (50-800 ppm), flow rate (10-60 ml h−1), and continuous contact with reaction medium (flow rate, 20 ml h−1 and concentration, 100 ppm) that affect aldicarb degradation were investigated in a packed-bed reactor. Increases in the flow rate decreased the conversion of aldicarb into its metabolites. On the other hand, increasing the substrate concentration up to 400 ppm led to an increase in the amount of aldicarb converted (max 16%). Beyond this, the proportion of aldicarb that converted was decreased, reaching approximately 7% at 800 ppm. The apparent kinetic parameters, K′m and Vmax, were determined to be as 310.11 ppm and 2.29 × 10−2 ppm s−1, ...
Kök FN, Wilkins RM, Cain RB, Arica MY, Alaeddinoğlu G, Hasirci V. Department of Biological Sciences, Middle East Technical University, Ankara, Turkey. Aldicarb loaded microspheres of carboxymethyl cellulose, CMC, of various compositions were prepared with the crosslinking action of Al(III). Into these microspheres, lignin was introduced as a filler to further regulate the rate of release. The encapsulation efficiency was low (4.15-13.00%) due to the high water solubility of aldicarb. Release into aqueous media was quite rapid and almost complete within 24h. Initial stages of the release (60% of AS released) was investigated to determine the release mechanism and it was found that release from the microspheres was governed by Fickian diffusion. Among the various parameters, the ratio of lignin to CMC and aldicarb to CMC were found to be influential on the rate of release from the crosslinked CMC-lignin microspheres. The soil behaviour confirmed the delayed release effect of the controlled ...
The small GTPase RHO-1 is an important regulator of neurotransmission. Caenorhabditis elegans nematodes expressing activated RHO-1 (G14V) in their cholinergic motor neurons (nRHO-1*) become hypersensitive to the acetylcholinesterase inhibitor aldicarb, demonstrating increased acetylcholine release, and acquire a highly loopy, uncoordinated locomotion. RHO-1 inhibits diacylglycerol kinase (DGK-1), and so increases the availability of diacylglycerol (DAG), a key second messenger for release at the presynaptic membrane. Inhibiting RHO-1 in a dgk-1 mutant causes a decrease in neurotransmitter release, demonstrating the presence of additional targets downstream of RHO-1. During a forward genetic screen for suppressors of the loopy locomotion of nRHO-1* animals we obtained a mutant, nz94, which carried an additional fainter phenotype, helping us identify it as an allele of unc-80, a large, conserved protein, important in the localization of NCA-1 and NCA-2, C. elegans homologues of the novel ...
The carbamate pesticide aldicarb is used for the control of insects, nematodes, and mites. It is now registered for use on cotton, sugar beets, sugar cane, potatoes, peanuts, and a variety of field- and nursery-grown ornamental plants.. A bioassay of aldicarb for possible carcinogenicity was conducted by administering the test chemical in feed to F344 rats and B6C3F1 mice.. Groups of 50 rats and 50 mice of each sex were administered aldicarb at one of two doses, either 2 or 6 ppm, for 103 weeks and then observed for an additional 0 to 2 weeks. Matched controls consisted of 25 untreated rats and 25 untreated mice of each sex. All surviving animals were killed at weeks 103 to 105.. Mean body weights of the dosed male and female rats were essentially the same as those of the corresponding controls. Mean body weights of the dosed male and female mice also were essentially the same as those of corresponding controls. Hyperactivity was noted in the dosed groups of mice. Survival was not affected ...
Acute symptoms of pesticide poisoning include headaches, vomiting,. tremors, lack of coordination, difficulty breathing or respiratory. depression, loss of consciousness, seizures and death. Chronic effects. of long-term pesticide exposure include impaired memory and concentration, disorientation, severe depression and confusion.. ● In India, home to over one third of the worlds cotton farmers, cotton. accounts for 54% of all pesticides used annually - despite occupying. just 5% of land under crops. In a single 5 month observation period, 97. cotton farmers experienced 323 separate incidents of ill health. Of these. 39% were associated with mild poisoning, 38% with moderate poisoning, and 6 % with severe poisoning.. ● A single drop of the pesticide aldicarb, absorbed through the skin can. kill an adult. Aldicarb is commonly used in cotton production and in. 2003 almost 1 million kilos was applied to cotton grown in the USA.. Aldicarb is also applied to cotton in 25 other countries ...
See how COMSOL can be used to simulate pesticide runoff and degradation patterns, important when determining if a pesticide is safe for use.
Founded in 2005, Consumerist® is an independent source of consumer news and information published by Consumer Media LLC, a not-for-profit subsidiary of Consumer Reports.. ...
Porcine, like human, LES is formed by the sling muscle on the angle of Hiss and the clasp component in lesser curvature (Preiksaitis and Diamant, 1997). We only included clasp strips that developed active tension and relaxed during stimulation of inhibitory motor neurons, ensuring that we had selected LES strips with intact innervation. We tested the effect of a nitric oxide donor, VIP, ATP, PACAP, a carbon monoxide donor, and CGRP because these substances colocalize in esophageal inhibitory motor neurons (Ny et al., 1995a; Uc et al., 1997). Colocalized substances can participate as neuromodulators, neurotransmitters, or with neurotrophic effects (Burnstock, 2004). We found that the nitric oxide donor, VIP, ATP, ADPβS, the carbon monoxide donor, and PACAP relaxed LES strips through a tetrodotoxin-insensitive mechanism, suggesting a direct effect on smooth muscle cells. Nitric oxide, ATP, and PACAP induced a complete LES relaxation, and CORM-1 and VIP were clearly less efficient, as observed in ...
Previously it has been proposed that the slow depolarization underlying the CMMC is produced by the removal of inhibitory neural activity (disinhibition) (4, 6, 18, 28, 30, 31). The fast oscillations, superimposed on the slow-depolarizing phase of the CMMC, were thought to be mediated entirely by the release of acetylcholine from cholinergic motor neurons that either caused myogenic oscillations in the muscle (4, 18) or the repetitive firing of excitatory junction potentials in the muscle (32). These previous experiments were performed in the presence of L-type Ca2+ channel antagonists (4, 30-32) that block slow-wave activity (36).. We still recorded robust spontaneous CMMCs in the depolarized nNOS−/− mouse colon despite the fact that neuronal nitric oxide, a major component of inhibitory neurotransmission to the muscle, had been knocked out. This initially suggested to us that a reduction in the release of NO from inhibitory motor neurons (disinhibition) was unlikely to play a major role in ...
• Ag Logic, a subsidiary of Maximum Economic Yield (MEY), has applied to the EPA for label clearance on a Temik-like product and expects the final answer by Oct. 23. • The product will not be Temik, it will be an aldicarb compound that is very similar to Temik.
Evidence that inhibitory motor neurons of the guinea-pig small intestine exhibit fast excitatory synaptic potentials mediated via P-2X receptors Journal Articles ...
From a pharmacological perspective, these substances act via the parasympathetic nervous system (PSNS) as reversible inhibitors of the enzyme acetylcholinesterase (AChE). Typically, acetylcholine (ACh) is released into the neural synaptic cleft and binds to ACh receptors post-synapse, which then relays a signal from the nerve. AChE halts the signal transmission via hydrolysis of ACh into acetate and choline. AChE functions rapidly and has a very high catalytic activity - it has been demonstrated that AChE can degrade about 25,000 molecules of ACh per second. Choline is then taken up by the presynaptic nerve and ACh is constructed from choline and Acetyl Coenzyme A (acetyl-CoA) via another enzyme, choline acetyltransferase. As AChE inhbitors, aldicarb and carbofuran inhibit or slow down the normal function of this enzymatic pathway of ACh which results in an accumulation of ACh in the neural synaptic cleft. This accumulation can result in devastating consequences for the organism. ...
SUETT, D.L. & JUKES, A.A. (1990). Some factors influencing the accelerated degradation and biological activity of aldicarb and carbofuran in field soils. Abstracts 7th International Congress of Pesticide Chemistry, Hamburg, Germany, August 1990, p. 71.. SUETT, D.L. & JUKES, A.A. (1988). Accelerated degradation of soil‑applied insecticides ‑ implications for control of damson‑hop aphid in hops. IOBC/WPRS Bulletin, XI/5, pp. 22-32 ...
Poisoned Peregrine Falcon (Falco peregrinus) preparing to return to the UK skies. The female bird and her brother were discovered near Buckfastleigh in Devon in June. Her brother later died. Officials suspect deliberate poisoning. Tests show he swallowed a highly toxic substance. A pigeon smeared in the toxic pesticide, aldicarb, was also found. A £1000 reward is being offered for any information leading to a conviction ...
Survival of juveniles of the seed-gall nematode, Anguina tritici, was used to assess the nematicidal efficacy of various substituted β-ketoesters and β-dicarbonyt compounds. In general, β-dicarbonyl compounds were more active than β-ketoesters. The activity of the esters and ketones was increased by introducing chloro, bromo, acetoxy or aryl groups at α- and β-positions. Some of the compounds have comparable activity to that of the commercial nematicide, aldicarb.
According to a news bulletin recently released by the ASPCA Animal Poison Control Center, permethrin insecticide and laundry detergent caused the greatest numbers of reported deaths.. Permithrins are the most common over-the-counter "flea and tick" treatment. Although relatively safe (if ineffective) when used on dogs as directed, it is a common and potentially fatal mistake to misapply the product on cats. This can cause the cat to die of convulsions. There is no antidote.. Liquid laundry detergent or the new individual detergent packs cause severe stomach upset in bot dogs and cats, followed by aspiration of the detergent into the lungs. The ensuing respiratory complications can be fatal.. Poison number 3 is topical Efundex, or 5-fluorouracil. Dogs who get a hold of the tube and ingest even a small amount of the cream develop GI upset, severe seizures and cardiac arrest.. Carbonate insecticides, ie Aldicarb (illegal in the US) and methomyl can cause acute collapse and patients referral to the ...
Automated behavioural fingerprinting of C. elegans mutants: Rapid advances in genetics, genomics, and imaging have given insight into the molecular and cellular
Apl-1 expression was induced in adult worms via heat shock. A single induction in day one adults mildly increased lifespan (5%) whereas regular apl-1 expression robustly increased lifespan (12-30%). Tissue specific expression had differing effects, neuron specific expression resulted in a decrease in lifespan whereas hypodermis specific expression resulted in lifespan extension ...
UCIL used to manufacture three different kinds of pesticides: Carbaryl (trade name Sevin), Aldicarb (trade name Temik) and a formulation of Carbaryl and gamma-hexachlorocyclohexane (trade name Sevidol). The plant also used heavy metals like mercury and chromium. Most of these products and elements are persistent and toxic. The CSE laboratory chose the same chemicals for its tests.. In October this year, one water and eight soil samples were collected from various places inside the factory. Eleven more water samples came from locations outside, ranging from colonies next to the factorys boundary to those 3.5 km away.. All the samples collected from within the factory were found to be highly contaminated. The waste stored within the premises had Carbaryl content of 9,856 parts per million (ppm) and mercury content of 1,065 ppm. The soil sample near the Sevidol plant had 2,782 ppm of Lindane; soil from solar evaporation pond had chromium content of 1,065 ppm, while that from the Sevin plant had ...
HPLC Application #18282: Carbamate Pesticides on Kinetex 2.6µm C18 50 x 4.6mm ID. Column used: Kinetex® 2.6 µm C18 100 Å, LC Column 50 x 4.6 mm, Ea Part#: 00B-4462-E0
Reagents flow rate: 0.3 mL/min Detection: Fluorometer: λex 330 nm, λem 465 nm The recommended gradient conditions are subject to change without notice. This may happen because of lot specific changes in the columns, or improvements in the overall method. The recommended gradient for the column will always be included in the column package, and it supersedes the information in this catalog. ...
At 4 a.m., July 4, 1985, three adults who ate a solid green watermelon purchased in Oakland, California, had rapid onset of nausea, vomiting, diarrhea, profuse sweating, excessive tearing, muscle fasciculations, and bradycardia. The most severely ill was a 59-year-old woman who had been receiving digoxin and who, on examination, had a heart rate of 32 and 4-second periods of asystole. The treating physician diagnosed cholinesterase-inhibitor poisoning, and the patient responded rapidly to atropine. The California Department of Health Services (CDHS) had been alerted the day before by Oregon State Health Division officials of similar, although milder, clusters of illness in Oregon associated with ingestion of striped watermelons, possibly of California origin. CDHS notified the San Francisco Bay Area Regional Poison Control Center to be alert for watermelon-associated illness. When the attending physician consulted the Poison Control Center, CDHS was alerted to the outbreak in California. CDHS ...
Ulmus parvifolia, commonly called Chinese elm or lacebark elm, is a medium-sized deciduous tree that typically grows to 40-50 (less frequently to 70) tall with a rounded crown and long pendulous branching. It is native to China, Korea and Japan. It is noted for its excellent foliage, multi-colored bark, rapid growth and good resistance to Dutch elm disease. Insignificant, small, reddish-green flowers appear in late summer. Flowers give way to single-seeded wafer-like samaras (each tiny seed is surrounded by a flattened circular papery wing) that mature in fall. Elliptic to ovate, shiny dark green leaves (to 3" long) have small teeth. Leaves typically turn an undistinguished dull yellow in fall, but sometimes produce more interesting yellows or reddish-purples. One of the most ornamental features of this tree is its mottled bark. On mature trees, bark flakes to reveal patches of gray, cream, orange, brown and green ...
The common species of thrips infesting cotton seedlings include flower thrips, Frankliniella tritici (Fitch); tobacco thrips, Frankliniella fusca (Hinds); western flower thrips, Frankliniella occidentalis (Pergande); onion thrips, Thrips tabaci (Lindeman); and soybean thrips, Neohydatothrips variabilis (Beach). In surveys of cotton seedlings at several locations in Louisiana, tobacco thrips was the most common species. The occurrence of flower thrips and soybean thrips was variable. Western flower thrips accounted for < 15% of adults collected at all locations, except two. The performance of acephate and imidacloprid applied as seed treatments and in-furrow, and aldicarb applied in-furrow was evaluated for thrips management across different production environments. Insecticide treatments reduced thrips densities and delayed development of thrips larval populations. The at-planting insecticides influenced thrips species composition in some instances. In studies to evaluate the effects of ...
2017 RTI International. RTI is a registered trademark and trade name of Research Triangle Institute. The RTI logo is a registered trademark of Research Triangle Institute. ...
This study firstly reports the development, characterisation, and application of thick-film acetylcholinesterase (AChE) biosensors based on a gold electrode modified with a mercaptobenzothiazole (MBT) self-assembled monolayer and either poly(omethoxyaniline) (POMA) or poly(2,5-dimethoxyaniline) (PDMA) in the presence of polystyrene(4-sulphonic acid) (PSSA). The Au/MBT/POMA-PSSA/AChE and Au/MBT/PDMA-PSSA/AChE biosensors were then applied to successfully detect standard organophosphorous and carbamate pesticides in a 0.1 M phosphate buffer, 0.1 M KCl (pH 7.2) solution. Secondly, it reports the construction of the Au/MBT/PANI/AChE/PVAc thick-film biosensor for the determination of certain organophosphate and carbamate pesticide solutions in selected aqueous organic solvent solutions ...
Click to buy 3 x Non-slip Replacement Pedal Covers Foot Board for Car Vehicle RIG-59581 from TinyDeal.com with wholesale price and free shipping!
Recent organic fertilizer treatments (cow manure, pig slurry, composts, or green manure) simultaneously increase insecticide adsorption onto soil and the insecticide soil persistence, indicating a mechanism of slow release of insecticide into soil by the organic matter. This occurred in sugar beet crops with aldicarb, thiofanox and imidacloprid; also, in leek, cauliflower and brussels sprouts crops with chlorpyrifos and chlorfenvinphos. In contrast, organic fertilizer treatments applied once or repeatedly in the past, have no significant influence on adsorption or persistence of insecticides; the same is observed for the old soil organic matter, when its soil concentrations change in limited ranges ...
Business Directory for Rodenticide Suppliers in Vadodara - Get contact details of Rodenticide Manufacturers, Wholesale Rodenticide Exporters, Best Rodenticide Traders & Distributors Across the Vadodara.
APL-1 overexpression using either the apl-1 or the snb-1 promoter, but not the pan-neuronal rab-3 promoter, caused a diminished chemotaxis response to both sodium acetate and benzaldehyde. Similarly, a short heat shock during adulthood to induce ubiquitous APL-1 expression was sufficient to cause an impaired chemotaxis response. These results suggest that APL-1 expression in non-neuronal cells decreases or disrupts the chemotaxis response. For instance, apl-1 signaling may interfere with the feedback from downstream neurons or non-neuronal tissue to the sensory neurons. Strikingly, the chemotaxis impairments of these transgenic animals were fully or partially restored by decreased activity of daf-2 insulin-IGF-1 receptor, daf-7 TGFβ, or daf-12 NHR signaling. Hence, the effects of APL-1 levels on chemotaxis are unlikely to be due to disrupted neuronal structure or neurodegeneration, but rather to modulation of the insulin/IGF-1 and/or DAF-12 NHR signaling pathways. Similarly, disruption of apl-1 ...
Rodenticides are chemical poisons used against rodents. Most all rodenticides are also harmful to humans if swallowed or absorbed through the skin in high enough quantities.
The male version of a whale tail. When a man's thong underware is hiked up so high, his pants are so low, or a combination of both, that you can see what resembles the sea creature's tail.
TORONTO--(Marketwire - Oct 29, 2012) - October 29, 2012 -Independent Committee Selects Cynapsus Novel Sublingual formulation of Apomorphine, as One of the Most Promising CNS Candidates- TORONTO, CANADA - Cynapsus Therapeutics Inc. (CTH: TSX V) today announced that its APL-130277 for Parkinsons was recognized as one of the Top Ten...

Controlled release of aldicarb from lignin loaded ionotropic hydrogel microspheres    [Koks Group]Controlled release of aldicarb from lignin loaded ionotropic hydrogel microspheres [Kok's Group]

Controlled release of aldicarb from lignin loaded ionotropic hydrogel microspheres. Kök FN, Wilkins RM, Cain RB, Arica MY, ... Among the various parameters, the ratio of lignin to CMC and aldicarb to CMC were found to be influential on the rate of ... Aldicarb loaded microspheres of carboxymethyl cellulose, CMC, of various compositions were prepared with the crosslinking ... The encapsulation efficiency was low (4.15-13.00%) due to the high water solubility of aldicarb. Release into aqueous media was ...
more infohttp://www.kokbiolab.com/doku.php?id=publications:controlled_release_of_aldicarb_from_a_lignin_loaded_ionotrophic_hydrogel

Biodegradation of aldicarb in a packed-bed reactor by immobilized Methylosinus    [Koks Group]Biodegradation of aldicarb in a packed-bed reactor by immobilized Methylosinus [Kok's Group]

Biodegradation of aldicarb in a packed-bed reactor by immobilized Methylosinus. Kok FN, Arica MY, Halicigil C, Alaeddinoglu G, ... publications/biodegradation_of_aldicarb_in_a_packed_bed_reactor_by_immobilized_methylosinus.txt · Last modified: 2009/12/06 03: ... Operation of the bioreactor in the recycled mode was much more efficient, degrading 50% of the aldicarb in 24 h and 100% in ... On the other hand, increasing the substrate concentration up to 400 ppm led to an increase in the amount of aldicarb converted ...
more infohttp://www.kokbiolab.com/doku.php?id=publications:biodegradation_of_aldicarb_in_a_packed_bed_reactor_by_immobilized_methylosinus

Aldicarb (PDS)Aldicarb (PDS)

See Also: Aldicarb (EHC 121, 1991) Aldicarb (IARC Summary & Evaluation, Volume 53, 1991) Aldicarb (ICSC) ... Aldicarb injected into hens eggs at a dose of 1.0 mg/egg produced no teratogenic effects. Aldicarb given to pregnant rats at ... Aldicarb should not be used on stored crops or products. 1.4.4 Unintended effects - Applied as directed aldicarb is not ... Mice fed a 1:1 ratio of aldicarb and aldicarb sulfone at dose levels from 2 to 36 mg/kg b.w. showed no treatment related ...
more infohttp://www.intox.org/databank/documents/chemical/aldicarb/pest53_e.htm

Epidemiologic Notes and Reports Aldicarb Food Poisoning from
Contaminated Melons -- CaliforniaEpidemiologic Notes and Reports Aldicarb Food Poisoning from Contaminated Melons -- California

Aldicarb has the lowest LD((50)) of any pesticide registered in the United States (LD((50((1 mg/kg body weight) (1). Aldicarb ... Aldicarb is a carbamate insecticide used in citrus groves and potato fields. Unlike organophosphates, which also interfere with ... Toxicological properties of aldicarb. Berkeley: California Department of Health Services, 1979; publication no. CA/DOH/AIHL/R- ... ASO is the primary toxic metabolite of aldicarb (Temik), a systemic pesticide not registered in the United States for use on ...
more infohttps://www.cdc.gov/mmwr/preview/mmwrhtml/00000721.htm

Simulating Pesticide Runoff, the Effects of Aldicarb | COMSOL BlogSimulating Pesticide Runoff, the Effects of Aldicarb | COMSOL Blog

For aldicarb and aldicarb sulfoxide, the toxicity is LD50 = 0.9 mg/kg; a very high toxicity, while aldicarb sulfone has a value ... When aldicarb degrades, it transforms first into the toxic chemicals aldicarb sulfoxide and aldicarb sulfone, and then is ... Concentration of the toxic species aldicarb, aldicarb sulfoxide, and aldicarb sulfone over a period of 100 days. ... The sorption, degradation, and volatilization of the three solutes, aldicarb, aldicarb sulfoxide, and aldicarb sulfone proceed ...
more infohttps://www.comsol.se/blogs/simulating-pesticide-runoff-the-effects-of-aldicarb/

Aldicarb - WikipediaAldicarb - Wikipedia

Aldicarb is one of the most widely used pesticides internationally, and is also one of the most environmentally toxic. Aldicarb ... A new aldicarb pesticide named AgLogic 15G, was approved by the EPA in December 2011 and is said to be entering the market in ... Aldicarb is a carbamate insecticide which is the active substance in the pesticide Temik. It is effective against thrips, ... Aldicarb is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. In case of severe ...
more infohttps://en.wikipedia.org/wiki/Aldicarb

Aldicarb-sulfone 100 µg/mL in Methanol- CAS Number 1646-88-4Aldicarb-sulfone 100 µg/mL in Methanol- CAS Number 1646-88-4

Achetez Aldicarb-sulfone 100 µg/mL in Methanol - Numéro CAS 1646-88-4 de LGC Standards. Sidentifier ou senregistrer pour ...
more infohttps://www.lgcstandards.com/FR/fr/Aldicarb-sulfone-100-g-mL-in-Methanol/p/U-PST-1215M100A01

Refined avian risk assessment for aldicarb in the United States - Moore - 2009 - Integrated Environmental Assessment and...Refined avian risk assessment for aldicarb in the United States - Moore - 2009 - Integrated Environmental Assessment and...

Aldicarb is a systemic insecticide sold in granular form under the trade name Temik®. It is applied directly to soil and is ... Next article in issue: Refined aquatic risk assessment for aldicarb in the United States Next article in issue: Refined aquatic ... Refined avian risk assessment for aldicarb in the United States. Authors. *. Dwayne RJ Moore,. Corresponding author*E-mail ... Thus, aldicarb granules may be mistaken for grit by birds. The Granular Pesticide Avian Risk Assessment Model (GranPARAM) is ...
more infohttp://onlinelibrary.wiley.com/doi/10.1897/IEAM_2009-022.1/full?globalMessage=0&systemMessage=Wiley+Online+Library+is+migrating+to+a+new+platform+powered+by+Atypon%2C+the+leading+provider+of+scholarly+publishing+platforms.+The+new+Wiley+Online+Library+will+be+migrated+over+the+weekend+of+February+24+and+25+and+will+be+live+on+February+26%2C+2018.+For+more+information%2C+please+visit+our+migration+page%3Ahttp%3A%2F%2Fwww.wileyactual.com%2FWOLMigration%2F

ASTM D7600 - 09e1 Standard Test Method for Determination of Aldicarb, Carbofuran, Oxamyl and Methomyl by Liquid Chromatography...ASTM D7600 - 09e1 Standard Test Method for Determination of Aldicarb, Carbofuran, Oxamyl and Methomyl by Liquid Chromatography...

... aldicarb, carbaryl, carbofuran, formetanate hydrochloride, methiocarb, methomyl, oxamyl, pirimicarb, ... ... ASTM D7645 - 10e1 Standard Test Method for Determination of Aldicarb, Aldicarb Sulfone, Aldicarb Sulfoxide, Carbofuran, ... ASTM D7645 - 10e1 Standard Test Method for Determination of Aldicarb, Aldicarb Sulfone, Aldicarb Sulfoxide, Carbofuran, ... No comments were found for ASTM D7600 - 09e1 Standard Test Method for Determination of Aldicarb, Carbofuran, Oxamyl and ...
more infohttps://www.environmental-expert.com/news/astm-d7600-09e1-standard-test-method-for-determination-of-aldicarb-carbofuran-oxamyl-and-methomyl-by-282255

AldicarbAldicarb

... ,2-Methyl-2-(methylthio)propanal O-[(methylamino)carbonyl]oxime,2-methyl-2-(methylthio)propionaldehyde O-( ...
more infohttp://www.druglead.com/cds/aldicarb.html

Aldicarb-sulfone | Bioneks®Aldicarb-sulfone | Bioneks®

Bioneks® Bioteknoloji henüz çok genç bir firma olmasına rağmen kurucularının üstlendiği misyon (ilke) ve sahip oldukları vizyon (ülkü) ile kısa sürede doğru hamleler yaparak pazarın hızla büyüyen ve güvenilen markası olmayı başarmıştır.
more infohttp://www.bioneks.com/aldicarb-sulfone-3

Pesticide aldicarb is back for use in South Carolina | Clemson University News and Stories, South CarolinaPesticide aldicarb is back for use in South Carolina | Clemson University News and Stories, South Carolina

The chemical aldicarb is coming back as AgLogic 15G. It will be available for use on cotton, peanuts and soybeans grown in ... The return of aldicarb certainly will be welcomed by agricultural producers.". Aldicarb is a chemical many growers relied on to ... Pesticide aldicarb is back for use in South Carolina. Denise Attaway, College of Agriculture, Forestry and Life Sciences; ... The chemical aldicarb is coming back as AgLogic 15G. It will be available for use on cotton, peanuts and soybeans grown in ...
more infohttp://newsstand.clemson.edu/mediarelations/pesticide-aldicarb-is-back-for-use-in-south-carolina/

ALDICARB- THE DEADLY KILLER ON OUR STREETSALDICARB- THE DEADLY KILLER ON OUR STREETS

Aldicarb is available from vendors selling their goods on the sidewalks of our cities. It is a street poison and it is leaving ... From what we learnt this one is the Aldicarb that is sold as Temik. Not a whole lot of dust, just the grey granules.. Now it ... The illegal Aldicarb comes in from Zimbabwe, Malawi, Mozambique, and as far as Tanzania so the borders are porous. Anyone can ... Wendy: If an animal in the wild was poisoned using Aldicarb what is the impact on the environment. Tim Snow: If an animal is ...
more infohttp://kaapsevryheidsburger.forumsmotion.com/t1047-aldicarb-the-deadly-killer-on-our-streets

Simulating Pesticide Runoff, the Effects of Aldicarb | COMSOL BlogSimulating Pesticide Runoff, the Effects of Aldicarb | COMSOL Blog

For aldicarb and aldicarb sulfoxide, the toxicity is LD50 = 0.9 mg/kg; a very high toxicity, while aldicarb sulfone has a value ... When aldicarb degrades, it transforms first into the toxic chemicals aldicarb sulfoxide and aldicarb sulfone, and then is ... Concentration of the toxic species aldicarb, aldicarb sulfoxide, and aldicarb sulfone over a period of 100 days. ... The sorption, degradation, and volatilization of the three solutes, aldicarb, aldicarb sulfoxide, and aldicarb sulfone proceed ...
more infohttps://www.comsol.co.in/blogs/simulating-pesticide-runoff-the-effects-of-aldicarb/

Regulation of Glutamate Signaling in the Sensorimotor Circuit by CASY-1A/Calsyntenin in Caenorhabditis elegans | GeneticsRegulation of Glutamate Signaling in the Sensorimotor Circuit by CASY-1A/Calsyntenin in Caenorhabditis elegans | Genetics

The Aldicarb assays were performed as described previously (Mahoney et al. 2006b). NGM plates containing Aldicarb at a final ... A-D) Aldicarb-induced paralysis at 80 or 105 min is shown for the indicated genotypes. The casy-1 Aldicarb hypersensitivity was ... The rate of Aldicarb-induced paralysis was found to vary in few of the experiments, although the Aldicarb concentration used in ... and after every 30 min during the Aldicarb assay. For this assay, Aldicarb plates were seeded with OP50 containing 0.8 mM all- ...
more infohttp://www.genetics.org/content/208/4/1553

μ2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans | JCBμ2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans | JCB

Plates with six different aldicarb final concentrations were prepared (0.1, 0.3, 0.5, 0.7, 0.9, and 1.1 mM). Aldicarb was ... S3 shows apm-2 aldicarb assay. Fig. S4 is a cartoon structure of apm-2∷GFP DNA constructs. Fig. S5 depicts the assembly of AP2 ... Aldicarb resistance assay. Each agar plate was seeded with bacteria and weighed to top spread plates with the appropriate ... Mutants lacking μ3 (apm-2(tm920)) are outwardly wild type but slightly aldicarb resistant. Again, μ2 and μ3 mutations do not ...
more infohttp://jcb.rupress.org/content/183/5/881

Akton- CAS Number 1757-18-2Akton- CAS Number 1757-18-2

Aldicarb. 100 mg. DRE-C10070000. Add to basket Aldicarb 100 µg/mL in Acetonitrile. Short expiry date due to chemical nature of ... Aldicarb-sulfoxide-nitrile. 10 mg. DRE-C10080800. Add to basket Aldicarb-sulfoxide. Short expiry date due to chemical nature of ... Aldicarb-oxime 10 µg/mL in Acetonitrile. 1 mL. DRE-LA10079500AL. Add to basket ... Aldicarb-sulfone. 100 mg. DRE-C10080000. Add to basket ...
more infohttps://www.lgcstandards.com/PL/en/Akton/p/DRE-C10050000

Abstract for TR-136Abstract for TR-136

Bioassay of Aldicarb for Possible Carcinogenicity CASRN: 116-06-3. Chemical Formula: C7H14N2O2S. Molecular Weight: 190.2656. ... The carbamate pesticide aldicarb is used for the control of insects, nematodes, and mites. It is now registered for use on ... A bioassay of aldicarb for possible carcinogenicity was conducted by administering the test chemical in feed to F344 rats and ... Groups of 50 rats and 50 mice of each sex were administered aldicarb at one of two doses, either 2 or 6 ppm, for 103 weeks and ...
more infohttps://ntp.niehs.nih.gov/results/pubs/longterm/reports/longterm/tr100199/abstracts/tr136/index.html

Popular Articles & Stories for August 13, 1985 - latimesPopular Articles & Stories for August 13, 1985 - latimes

Carbide to Suspend Aldicarb Work, Pay Expenses of Victims Associated Press. *. Pope Asks Africans to Forgive Christians for ...
more infohttp://articles.latimes.com/1985/aug/13

Abstract for IMM89025Abstract for IMM89025

Aldicarb oxime is also anintermediate in the metabolism of aldicarb.. Aldicarb oxime was nominated to the. NTP. for ... Aldicarb oxime [2-Methyl-2-(methyl-thio)-propanal,oxime] is produced primarily as an intermediate in the synthesisof aldicarb [ ... Aldicarb oxime was administered bygavage at doses of 1, 7.5 or 15 mg/kg daily for 14 consecutivedays. The highest dose was the ... Immunotoxicity of Aldicarb Oxime in Female B6C3F1 Mice. CASRN: 1646-75-9. Chemical Formula: C5H11NOS. Molecular Weight: ...
more infohttps://ntp.niehs.nih.gov/testing/types/imm/abstracts/imm89025/index.html

Carbendazim - WikipediaCarbendazim - Wikipedia

Carbendazim is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is also employed as a casting worm control agent in amenity turf situations such as golf greens, tennis courts etc. and in some countries is licensed for that use only.[2] The fungicide is used to control plant diseases in cereals and fruits, including citrus, bananas, strawberries, pineapples, and pomes.[3] It is also controversially used in Queensland, Australia on macadamia plantations.[4] A 4.7% solution of carbendazim hydrochloride, sold as Eertavas, is marketed as a treatment for Dutch elm disease. Studies have found high doses of carbendazim cause infertility and destroy the testicles of laboratory animals.[5][6] Maximum pesticide residue limits (MRLs) have reduced since discovering its harmful effects. The MRLs for fresh produce in the EU are now between 0.1 and 0.7 mg/kg with the exception of loquat, which is 2 mg/kg.[7] The limits for more commonly consumed citrus and pome fruits are ...
more infohttps://en.wikipedia.org/wiki/Carbendazim

How to Comply with Requirements to Protect California Red-legged Frog from Pesticides | Protecting Endangered Species from...How to Comply with Requirements to Protect California Red-legged Frog from Pesticides | Protecting Endangered Species from...

The injunction addresses pesticide use only within and around certain geographic areas designated by the US Fish and Wildlife Service as critical habitat, and specified non-critical habitat sections. Sections are defined one-square mile areas of land, based on the Meridian-Township-Range-Section (MTRS) geographic system. These geographic areas are within one or more of 33 counties within California.. Are you planning to apply the pesticide in one or more of the following counties in California? If you answer "no", the courts injunction does not apply to the pesticide application. If you answer "yes", click on the county name to view a map of critical habitat and non-critical habitat sections within that county to which the injunction applies.. Is your proposed use within 400 feet of the general critical habitat areas or non-critical habitat sections? If you answer "no", the courts injunction does not apply to your pesticide application. If you answer "yes", continue to step 3.. You will need ...
more infohttps://www.epa.gov/endangered-species/how-comply-requirements-protect-california-red-legged-frog-pesticides

GV (nerve agent) - WikipediaGV (nerve agent) - Wikipedia

GV (IUPAC name: 2-(Dimethylamino)ethyl N,N-dimethylphosphoramidofluoridate) is an organophosphate nerve agent. GV is a part of a new series of nerve agents with properties similar to both the "G-series" and "V-series". It is a potent acetylcholinesterase inhibitor with properties similar to other nerve agents, being a highly poisonous vapour. Treatment for poisoning with GV involves drugs such as atropine, benactyzine, obidoxime, and HI-6.[1][2] ...
more infohttps://en.wikipedia.org/wiki/GV_

Chemical control of nematodes: efficiency and side-effectsChemical control of nematodes: efficiency and side-effects

Aldicarb 5-10 In bands for nursery use Banana Radopholus similis and/or Carbofuran 2-4 ga.i. per plant Applied around plant 2-3 ... Aldicarb 5.5-11.0 Annual treatment applied along drip-line Grape Meloidogyne spp. Fenamiphos. (e.c. formulation) 10.0 In bands ...
more infohttp://www.fao.org/docrep/v9978e/v9978e08.htm
  • This method has been investigated for use with reagent and surface water for the selected carbamates: aldicarb, carbofuran, oxamyl and methomyl. (environmental-expert.com)
  • 1.1 This procedure covers the determination of aldicarb, carbofuran, oxamyl and methomyl (referred to collectively as carbamates in this test method) in surface water by direct injection using liquid chromatography (LC) and detected with tandem mass spectrometry (MS/MS). These analytes are qualitatively and quantitatively determined by this method. (environmental-expert.com)
  • Aldicarb is a fast-acting cholinesterase inhibitor, causing rapid accumulation of acetylcholine at the synaptic cleft. (wikipedia.org)
  • By looking at the reaction mechanism of the pesticide's degradation, we can determine the decomposition kinetics and mass balance equations for aldicarb and its decay products. (comsol.se)
  • The degradation capacity of immobilized bacteria, different parameters such as substrate concentration (50-800 ppm), flow rate (10-60 ml h−1), and continuous contact with reaction medium (flow rate, 20 ml h−1 and concentration, 100 ppm) that affect aldicarb degradation were investigated in a packed-bed reactor. (kokbiolab.com)
  • needs update] Tres Pasitos, a mouse, rat, and roach killer that contains high concentrations of aldicarb, has been illegally imported into the United States from Mexico and other Latin American countries. (wikipedia.org)
  • Formulated aldicarb may be used concurrently with many fertilizers or other pesticides. (intox.org)
  • Aldicarb poisoning from agricultural water runoff has led to the destruction of healthy ecosystems and the irreversible poisoning of fertile agricultural land. (wikipedia.org)
  • Jeremy Greene , entomologist at Clemson's Edisto Research and Education Center , said the return of aldicarb is "great news" for agricultural producers. (clemson.edu)
  • The return of aldicarb certainly will be welcomed by agricultural producers. (clemson.edu)
  • Groups of 50 rats and 50 mice of each sex were administered aldicarb at one of two doses, either 2 or 6 ppm, for 103 weeks and then observed for an additional 0 to 2 weeks. (nih.gov)
  • Aldicarb oxime was administered bygavage at doses of 1, 7.5 or 15 mg/kg daily for 14 consecutivedays. (nih.gov)
  • 1.4.2 Susceptible pests - Aldicarb is effective against various insects (especially aphids, whiteflies, leaf miners, flea beetles and ground beetles), mites and nematodes on field crops, some vegetable and fruit crops, cotton and ornamentals in commercial plantings. (intox.org)
  • Aldicarb should not be used on stored crops or products. (intox.org)
  • In the United States, aldicarb was approved by the USEPA for use by professional pesticide applicators on a variety of crops, including cotton, beans, and others. (wikipedia.org)
  • Cotton, peanut and soybean producers in South Carolina will soon have aldicarb to use in their fight against insects and nematodes. (clemson.edu)
  • T cellresponses to mitogens (Con A and PHA) and allogeneic cells (MLR)were all unaffected by exposure to aldicarb oxime. (nih.gov)
  • With respect to innate immunity, naturalkiller cell function and peritoneal macrophage number and functionswere unaffected by aldicarb oxime exposure. (nih.gov)
  • Streptococcus pneumoniae,Listeria monocytogenes, and the B16F10 pulmonary metastaticmelanoma models were all unaffected by exposure to aldicarb oxime. (nih.gov)
  • A bioassay of aldicarb for possible carcinogenicity was conducted by administering the test chemical in feed to F344 rats and B6C3F1 mice. (nih.gov)
  • It is concluded that under the conditions of this bioassay, technical-grade aldicarb was not carcinogenic for F344 rats or B6C3F1 mice of either sex. (nih.gov)
  • The (U.S.) cotton crop has suffered with declining availability of aldicarb. (clemson.edu)
  • Aldicarb oxime [2-Methyl-2-(methyl-thio)-propanal,oxime] is produced primarily as an intermediate in the synthesisof aldicarb [2-methyl-2-(methylthio)-prioionaldehyde)-(methylcarbamoyl)oxime] which is used as a pesticide. (nih.gov)
  • Aldicarb is a chemical many growers relied on to help with control of early-season insect pests and nematodes. (clemson.edu)
  • When setting up a pesticide runoff system, we can imagine that the aldicarb is contained in a ring of water sitting on the ground. (comsol.se)
  • FAAT 1988, aldicarb was found not to affect theimmune system. (nih.gov)
  • Operation of the bioreactor in the recycled mode was much more efficient, degrading 50% of the aldicarb in 24 h and 100% in four days. (kokbiolab.com)
  • 1.4.4 Unintended effects - Applied as directed aldicarb is not phytotoxic. (intox.org)
  • In South Africa (where Aldicarb is popularly known as Two Step) it is widely used by burglars to poison dogs. (wikipedia.org)
  • The technical product is 94.7-97.7% pure aldicarb. (intox.org)
  • Aldicarb is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities. (wikipedia.org)