Ethanolamine: A viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.Ethanolamine Ammonia-Lyase: An enzyme that catalyzes the deamination of ethanolamine to acetaldehyde. EC 4.3.1.7.Desulfovibrio gigas: A species of gram-negative, anaerobic, spiral-shaped bacteria originally isolated from a saltwater pond in France. It contains a well-characterized metabolic pathway that enables it to survive transient contacts with OXYGEN.Metabolomics: The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.Aldehyde Oxidoreductases: Oxidoreductases that are specific for ALDEHYDES.British Columbia: A province of Canada on the Pacific coast. Its capital is Victoria. The name given in 1858 derives from the Columbia River which was named by the American captain Robert Gray for his ship Columbia which in turn was named for Columbus. (From Webster's New Geographical Dictionary, 1988, p178 & Room, Brewer's Dictionary of Names, 1992, p81-2)Tungsten: Tungsten. A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. It is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus.Canada: The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Alberta: A province of western Canada, lying between the provinces of British Columbia and Saskatchewan. Its capital is Edmonton. It was named in honor of Princess Louise Caroline Alberta, the fourth daughter of Queen Victoria. (From Webster's New Geographical Dictionary, 1988, p26 & Room, Brewer's Dictionary of Names, 1992, p12)Aldehydes: Organic compounds containing a carbonyl group in the form -CHO.Aldehyde Reductase: An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.Lipid Peroxidation: Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor.Imidazolidines: Compounds based on reduced IMIDAZOLINES which contain no double bonds in the ring.AcroleinKinetics: The rate dynamics in chemical or physical systems.Sorbitol: A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. It is also used in many manufacturing processes, as a pharmaceutical aid, and in several research applications.Fatty Acids, Unsaturated: FATTY ACIDS in which the carbon chain contains one or more double or triple carbon-carbon bonds.Apoenzymes: The protein components of enzyme complexes (HOLOENZYMES). An apoenzyme is the holoenzyme minus any cofactors (ENZYME COFACTORS) or prosthetic groups required for the enzymatic function.Fatty Acids: Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Saccharomyces cerevisiae: A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.Saccharomyces cerevisiae Proteins: Proteins obtained from the species SACCHAROMYCES CEREVISIAE. The function of specific proteins from this organism are the subject of intense scientific interest and have been used to derive basic understanding of the functioning similar proteins in higher eukaryotes.Fungal Proteins: Proteins found in any species of fungus.Genes, Fungal: The functional hereditary units of FUNGI.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).Gene Expression Regulation, Fungal: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in fungi.Saccharomyces: A genus of ascomycetous fungi of the family Saccharomycetaceae, order SACCHAROMYCETALES.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Titrimetry: The determination of the concentration of a given component in solution (the analyte) by addition of a liquid reagent of known strength (the titrant) until an equivalence point is reached (when the reactants are present in stoichiometric proportions). Often an indicator is added to make the equivalence point visible (e.g., a change in color).

Nitrate-dependent regulation of acetate biosynthesis and nitrate respiration by Clostridium thermoaceticum. (1/1279)

Nitrate has been shown to shunt the electron flow in Clostridium thermoaceticum from CO2 to nitrate, but it did not influence the levels of enzymes involved in the Wood-Ljungdahl pathway (J. M. Frostl, C. Seifritz, and H. L. Drake, J. Bacteriol. 178:4597-4603, 1996). Here we show that under some growth conditions, nitrate does in fact repress proteins involved in the Wood-Ljungdahl pathway. The CO oxidation activity in crude extracts of nitrate (30 mM)-supplemented cultures was fivefold less than that of nitrate-free cultures, while the H2 oxidation activity was six- to sevenfold lower. The decrease in CO oxidation activity paralleled a decrease in CO dehydrogenase (CODH) protein level, as confirmed by Western blot analysis. Protein levels of CODH in nitrate-supplemented cultures were 50% lower than those in nitrate-free cultures. Western blots analyses showed that nitrate also decreased the levels of the corrinoid iron-sulfur protein (60%) and methyltransferase (70%). Surprisingly, the decrease in activity and protein levels upon nitrate supplementation was observed only when cultures were continuously sparged. Northern blot analysis indicates that the regulation of the proteins involved in the Wood-Ljungdahl pathway by nitrate is at the transcriptional level. At least a 10-fold decrease in levels of cytochrome b was observed with nitrate supplementation whether the cultures were sparged or stoppered. We also detected nitrate-inducible nitrate reductase activity (2 to 39 nmol min-1 mg-1) in crude extracts of C. thermoaceticum. Our results indicate that nitrate coordinately represses genes encoding enzymes and electron transport proteins in the Wood-Ljungdahl pathway and activates transcription of nitrate respiratory proteins. CO2 also appears to induce expression of the Wood-Ljungdahl pathway genes and repress nitrate reductase activity.  (+info)

Aldehyde oxidase-dependent marked species difference in hepatic metabolism of the sedative-hypnotic, zaleplon, between monkeys and rats. (2/1279)

A marked difference in hepatic activity of aldehyde oxidase between rats and monkeys was found to be responsible for the previously reported marked species difference in the metabolism of Zaleplon in vivo. In the postmitochondrial fractions, S-9s, from liver homogenates of these animals, Zaleplon was transformed in the presence of NADPH into the side chain oxidation product, N-desethyl-Zaleplon, and the aromatic ring oxidation product, 5-oxo-Zaleplon. In the rat S-9, N-desethyl-Zaleplon and 5-oxo-Zaleplon were a major and a very minor metabolites, respectively. However, in the monkey S-9, Zaleplon was transformed into 5-oxo-Zaleplon at a much higher rate than that for N-desethyl-Zaleplon formation. N-Desethyl-Zaleplon was formed in the monkey S-9 at a rate almost equal to that in the rat S-9. N-Desethyl-5-oxo-Zaleplon was formed at a minor rate only in the monkey S-9 through N-desethyl-Zaleplon as an obligatory intermediate. The hepatic activity for the formation of 5-oxo-Zaleplon in the monkey and rat was localized in cytosol and did not require NADPH. Sensitivity to various inhibitors and requirement of water as oxygen source, using H218O, strongly suggested that the hepatic cytosolic formation of 5-oxo-Zaleplon was mediated by aldehyde oxidase. N-Desethyl-Zaleplon was formed in the presence of NADPH by microsomes from the liver of rats and monkeys, and its formation was strongly suggested using various cytochrome P-450 inhibitors to be mediated by a number of cytochrome P-450 isoforms, such as 3A, 2C, and 2D subfamilies.  (+info)

A genetic linkage map of rat chromosome 9 with a new locus for variant activity of liver aldehyde oxidase. (3/1279)

A genetic linkage map of rat chromosome 9 consisting of five loci including a new biochemical marker representing a genetic variation of the activity of the liver aldehyde oxidase, (Aox) was constructed. Linkage analysis of the five loci among 92 backcross progeny of (WKS/Iar x IS/Iar)F1 x WKS/Iar revealed significant linkages between these loci. Minimizing crossover frequency resulted in the best gene order: Aox-D9Mit4-Gls-Cryg-Tp53l1. The homologues of the Cryg, Gls, and Aox genes have been mapped on mouse chromosome 1 and human chromosome 2q. The present findings provide further evidence for the conservation of synteny among these regions of rat, mouse, and human chromosomes.  (+info)

Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation system in Pseudomonas aeruginosa: cloning and sequencing of the genes encoding cytochrome c550 and an adjacent acetaldehyde dehydrogenase. (4/1279)

Pseudomonas aeruginosa ATCC 17933 grown aerobically on ethanol produces a soluble cytochrome c550 together with a quinoprotein ethanol dehydrogenase. A 3.2 kb genomic DNA fragment containing the gene encoding cytochrome c550 was cloned and sequenced. Two other complete and two truncated ORFs were also identified. A truncated ORF encoding the quinoprotein ethanol dehydrogenase (exaA) was found upstream of the cytochrome c550 gene (exaB) and in reverse orientation. An ORF encoding a NAD(+)-dependent acetaldehyde dehydrogenase (exaC) was located downstream of the cytochrome c550 gene and in the same orientation. Another ORF showed similarity to the pqqA gene and a truncated ORF similarity to the pqqB gene, both involved in the biosynthesis of the prosthetic group PQQ. The organization of these genes was found to be different from the well-studied methanol oxidation system in methylotrophic bacteria. The deduced amino acid sequence of cytochrome c550 from P. aeruginosa showed some similarity to cytochrome c6 of the alga Chlamydomonas reinhardtii and the haem domain of quinohaemoprotein alcohol dehydrogenases of acetic acid bacteria, but no similarity to the soluble cytochrome cL of the quinoprotein methanol oxidation system of methylotrophs could be detected. A mutant of P. aeruginosa with an interrupted cytochrome c550 gene was unable to grow on ethanol, which proves that cytochrome c550 is an essential component of the ethanol oxidation system in this organism.  (+info)

Xenopus cytosolic thyroid hormone-binding protein (xCTBP) is aldehyde dehydrogenase catalyzing the formation of retinoic acid. (5/1279)

Amino acid sequencing of an internal peptide fragment derived from purified Xenopus cytosolic thyroid hormone-binding protein (xCTBP) demonstrates high similarity to the corresponding sequence of mammalian aldehyde dehydrogenase 1 (ALDH1) (Yamauchi, K., and Tata, J. R. (1994) Eur. J. Biochem. 225, 1105-1112). Here we show that xCTBP was co-purified with ALDH and 3,3',5-triiodo-L-thyronine (T3) binding activities. By photoaffinity labeling with [125I]T3, a T3-binding site in the xCTBP was estimated to reside in amino acid residues 93-114, which is distinct from the active site of the enzyme but present in the NAD+ binding domain. The amino acid sequences deduced from the two isolated xALDH1 cDNAs (xALDH1-I and xALDH1-II) were 94.6% identical to each other and very similar to those of mammalian ALDH1 enzymes. The two recombinant xALDH1 proteins exhibit both T3 binding activity and ALDH activity converting retinal to retinoic acid (RA), which are similar to those of xCTBP. The mRNAs were present abundantly in kidney and intestine of adult female Xenopus. Interestingly, their T3 binding activities were inhibited by NAD+ and NADH but not by NADP+ and NADPH, whereas NAD+ was required for their ALDH activities. Our results demonstrate that xCTBP is identical to ALDH1 and suggest that this protein might modulate RA synthesis and intracellular level of free T3.  (+info)

Metabolism of daunorubicin by a barbiturate-sensitive aldehyde reductase from rat liver. (6/1279)

A barbiturate-sensitive aldehyde reductase was purified to homogeneity from rat liver and shown to metabolize the cancer-chemotherapeutic antibiotic daunorubicin. The aldehyde reductase may have important roles in the metabolism of exogeneous drugs as well as the aldehyde derivatives of the biogenic amines.  (+info)

The choline-converting pathway in Staphylococcus xylosus C2A: genetic and physiological characterization. (7/1279)

A Staphylococcus xylosus C2A gene cluster, which encodes enzymes in the pathway for choline uptake and dehydrogenation (cud), to form the osmoprotectant glycine betaine, was identified. The cud locus comprises four genes, three of which encode proteins with significant similarities to those known to be involved in choline transport and conversion in other organisms. The physiological role of the gene products was confirmed by analysis of cud deletion mutants. The fourth gene possibly codes for a regulator protein. Part of the gene cluster was shown to be transcriptionally regulated by choline and elevated NaCl concentrations as inducers.  (+info)

The strict molybdate-dependence of glucose-degradation by the thermoacidophile Sulfolobus acidocaldarius reveals the first crenarchaeotic molybdenum containing enzyme--an aldehyde oxidoreductase. (8/1279)

In order to investigate the effects of trace elements on different metabolic pathways, the thermoacidophilic Crenarchaeon Sulfolobus acidocaldarius (DSM 639) has been cultivated on various carbon substrates in the presence and absence of molybdate. When grown on glucose (but neither on glutamate nor casein hydrolysate) as sole carbon source, the lack of molybdate results in serious growth inhibition. By analysing cytosolic fractions of glucose adapted cells for molybdenum containing compounds, an aldehyde oxidoreductase was detected that is present in the cytosol to at least 0.4% of the soluble protein. With Cl2Ind (2,6-dichlorophenolindophenol) as artificial electron acceptor, the enzyme exhibits oxidizing activity towards glyceraldehyde, glyceraldehyde-3-phosphate, isobutyraldehyde, formaldehyde, acetaldehyde and propionaldehyde. At its pH-optimum (6.7), close to the intracellular pH of Sulfolobus, the glyceraldehyde-oxidizing activity is predominant. The protein has an apparent molecular mass of 177 kDa and consists of three subunits of 80.5 kDa (alpha), 32 kDa (beta) and 19.5 kDa (gamma). It contains close to one Mo, four Fe, four acid-labile sulphides and four phosphates per protein molecule. Methanol extraction revealed the existence of 1 FAD per molecule and 1 molybdopterin per molecule, which was identified as molybdopterin guanine dinucleotide on the basis of perchloric acid cleavage and thin layer chromatography. EPR-spectra of the aerobically prepared enzyme exhibit the so-called 'desulpho-inhibited'-signal, known from chemically modified forms of molybdenum containing proteins. Anaerobically prepared samples show both, the signals arising from the active molybdenum-cofactor as well as from the two [2Fe-2S]-clusters. According to metal-, cofactor-, and subunit-composition, the enzyme resembles the members of the xanthine oxidase family. Nevertheless, the melting point and long-term thermostability of the protein are outstanding and perfectly in tune with the growth temperature of S. acidocaldarius (80 degrees C). The findings suggest the enzyme to function as a glyceraldehyde oxidoreductase in the course of the nonphosphorylated Entner-Doudoroff pathway and thereby may attribute a new physiological role to this class of enzyme.  (+info)

*Aldehyde ferredoxin oxidoreductase

In enzymology, an aldehyde ferredoxin oxidoreductase (EC 1.2.7.5) is an enzyme that catalyzes the chemical reaction an aldehyde ... Aldehyde Ferredoxin Oxidoreductase is a member of an AOR family, which includes glyceraldehyde-3-phosphate ferredoxin ... The systematic name of this enzyme class is aldehyde:ferredoxin oxidoreductase. This enzyme is also called AOR. It is a ... Roy R, Dhawan IK, Johnson MK, Rees DC, Adams MW (2006-04-15). Handbook of Metalloproteins: Aldehyde Ferredoxin Oxidoreductase ( ...

*Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an ... Roy R, Menon AL, Adams MW (2001). "Aldehyde oxidoreductases from Pyrococcus furiosus". Methods Enzymol. Methods in Enzymology. ... The systematic name of this enzyme class is D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase. Other names in common use ... Mukund S, Adams MW (1995). "Glyceraldehyde-3-phosphate ferredoxin oxidoreductase, a novel tungsten-containing enzyme with a ...

*Alcohol dehydrogenase (nicotinoprotein)

Van Ophem, P.W.; Van Beeumen, J.; Duine, J.A. (1993). "Nicotinoprotein [NAD(P)-containing] alcohol/aldehyde oxidoreductases. ... N-dimethyl-4-nitrosoaniline oxidoreductase) is an enzyme with systematic name ethanol:acceptor oxidoreductase. This enzyme ... catalyst for coenzyme-independent oxidation of a broad spectrum of alcohols and the interconversion of alcohols and aldehydes ...

*Eubacterium acidaminophilum

"Tungsten-containing aldehyde oxidoreductase of Eubacterium acidaminophilum". European Journal of Biochemistry / FEBS. 271 (1): ...

*Methanol dehydrogenase (nicotinoprotein)

Van Ophem, P.W.; Van Beeumen, J.; Duine, J.A. (1993). "Nicotinoprotein [NAD(P)-containing] alcohol/aldehyde oxidoreductases. ... N-dimethyl-4-nitrosoaniline oxidoreductase) is an enzyme with systematic name methanol:acceptor oxidoreductase. This enzyme ... dimethyl-4-nitrosoaniline oxidoreductase from Mycobacterium sp. strain JC1 (DSM 3803)". Microbiology. 156 (Pt 2): 463-471. doi: ... dimethyl-4-nitrosoaniline oxidoreductases from the gram-positive methylotrophic bacteria Amycolatopsis methanolica and ...

*Aldehyde dehydrogenase (FAD-independent)

... acceptor oxidoreductase (FAD-independent). Other names in common use include aldehyde oxidase, aldehyde oxidoreductase, Mop, ... This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with ... Andrade SL, Brondino CD, Feio MJ, Moura I, Moura JJ (2000). "Aldehyde oxidoreductase activity in Desulfovibrio alaskensis NCIMB ... "Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas". Science. 270 (5239): 1170-6. doi: ...

*Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain

"Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas". Science. 270 (5239): 1170-6. doi: ... Aldehyde oxidase (EC 1.2.3.1) catalyzes the conversion of an aldehyde in the presence of oxygen and water to an acid and ... The aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain is an evolutionary conserved protein domain. ...

*Cofactor (biochemistry)

... tungsten in the aldehyde ferredoxin oxidoreductase of the thermophilic archaean Pyrococcus furiosus, and even cadmium in the ... aldehyde ferredoxin oxidoreductase". Science. 267 (5203): 1463-9. doi:10.1126/science.7878465. PMID 7878465. Lane TW, Morel FM ...

*List of MeSH codes (D08)

... aldehyde oxidoreductases MeSH D08.811.682.657.163.249 --- aldehyde dehydrogenase MeSH D08.811.682.657.163.249.750 --- omega- ... amino acid oxidoreductases MeSH D08.811.682.664.500.062 --- alanine dehydrogenase MeSH D08.811.682.664.500.125 --- d-amino-acid ... succinate cytochrome c oxidoreductase MeSH D08.811.600.250.875.249 --- electron transport complex ii MeSH D08.811.600.250. ... aldehyde lyases MeSH D08.811.520.224.062.250 --- 2-dehydro-3-deoxyphosphoheptonate aldolase MeSH D08.811.520.224.062.400 --- ...

*Ferredoxin

... such as aldehyde oxidoreductase (N-terminal), xanthine oxidase (N-terminal), phthalate dioxygenase reductase (C-terminal), ... NADP+ oxidoreductase EC 1.18.1.2. Ferredoxins are small proteins containing iron and sulfur atoms organized as iron-sulfur ...

*Carboxylate reductase

The systematic name of this enzyme class is aldehyde:acceptor oxidoreductase. This enzyme is also called aldehyde:(acceptor) ... This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with ... In enzymology, a carboxylate reductase (EC 1.2.99.6) is an enzyme that catalyzes the chemical reaction an aldehyde + acceptor ... oxidoreductase. This enzyme participates in pyruvate metabolism. It employs one cofactor, tungsten. White H, Strobl G, Feicht R ...

*Aldehyde dehydrogenase (NADP+)

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ... The systematic name of this enzyme class is aldehyde:NADP+ oxidoreductase. Other names in common use include NADP+-acetaldehyde ... In enzymology, an aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) is an enzyme that catalyzes the chemical reaction an aldehyde + ... Adachi O, Matsushita K, Shinagawa E & Ameyama M (1980). "Crystallization and properties of NADP-dependent aldehyde ...

*Sabyasachi Sarkar

... the Tungsten Sites of Inactive and Active Forms of Hyperthermophilic Pyrococcus furiosus Aldehyde Ferredoxin Oxidoreductase". ...

*Aryl-aldehyde dehydrogenase (NADP+)

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ... The systematic name of this enzyme class is aryl-aldehyde:NADP+ oxidoreductase (ATP-forming). Other names in common use include ... 1. Purification and properties of aryl-aldehyde: NADP-oxidoreductase from Neurospora crassa]". Eur. J. Biochem. 8 (3): 413-9. ... "Formation and reduction of intermediate acyladenylate by aryl-aldehyde. NADP oxidoreductase from Neurospora crassa". Eur. J. ...

*Abscisic-aldehyde oxidase

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with ... The systematic name of this enzyme class is abscisic-aldehyde:oxygen oxidoreductase. Other names in common use include abscisic ... In enzymology, an abscisic-aldehyde oxidase (EC 1.2.3.14) is an enzyme that catalyzes the chemical reaction abscisic aldehyde ... Seo M, Koiwai H, Akaba S, Komano T, Oritani T, Kamiya Y, Koshiba T (2000). "Abscisic aldehyde oxidase in leaves of Arabidopsis ...

*Aryl-aldehyde dehydrogenase

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ... The systematic name of this enzyme class is aryl-aldehyde:NAD+ oxidoreductase. This enzyme participates in tyrosine metabolism ... In enzymology, an aryl-aldehyde dehydrogenase (EC 1.2.1.29) is an enzyme that catalyzes the chemical reaction an aromatic ... H+ The 3 substrates of this enzyme are aromatic aldehyde, NAD+, and H2O, whereas its 3 products are aromatic acid, NADH, and H+ ...

*Long-chain-fatty-acyl-CoA reductase

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ... The systematic name of this enzyme class is long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming). Other names in common ... H+ The 3 substrates of this enzyme are long-chain aldehyde, CoA, and NADP+, whereas its 3 products are long-chain acyl-CoA, ... is an enzyme that catalyzes the chemical reaction a long-chain aldehyde + CoA + NADP+ ⇌ {\displaystyle \rightleftharpoons } a ...

*Aldehyde dehydrogenase (NAD+)

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ... NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, propionaldehyde dehydrogenase, and aldehyde ... The systematic name of this enzyme class is aldehyde:NAD+ oxidoreductase. Other names in common use include CoA-independent ... In enzymology, an aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) is an enzyme that catalyzes the chemical reaction an aldehyde + ...

*Betaine-aldehyde dehydrogenase

NAD+ oxidoreductase. Other names in common use include betaine aldehyde oxidase, BADH, betaine aldehyde dehydrogenase, and BetB ... This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ... In enzymology, a betaine-aldehyde dehydrogenase (EC 1.2.1.8) is an enzyme that catalyzes the chemical reaction betaine aldehyde ... ROTHSCHILD HA, BARRON ES (1954). "The oxidation of betaine aldehyde by betaine aldehyde dehydrogenase". J. Biol. Chem. 209 (2 ...

*Artemisinic aldehyde Delta11(13)-reductase

NADP+ oxidoreductase. This enzyme catalyses the following chemical reaction (11R)-dihydroartemisinic aldehyde + NADP+ ⇌ {\ ... Artemisinic aldehyde Delta11(13)-reductase (EC 1.3.1.92, Dbr2) is an enzyme with systematic name artemisinic aldehyde: ... Artemisinic aldehyde Delta11(13)-reductase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... displaystyle \rightleftharpoons } artemisinic aldehyde + NADPH + H+ This enzyme i present in Artemisia annua. Bertea, C.M.; ...

*Aldehyde dehydrogenase (pyrroloquinoline-quinone)

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with ... The systematic name of this enzyme class is aldehyde:(pyrroloquinoline-quinone) oxidoreductase. This enzyme is also called ... In enzymology, an aldehyde dehydrogenase (pyrroloquinoline-quinone) (EC 1.2.99.3) is an enzyme that catalyzes the chemical ... Patel RN, Hou CT, Derelanko P, Felix A (1980). "Purification and properties of a heme-containing aldehyde dehydrogenase from ...

*Aryl-aldehyde oxidase

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with ... The systematic name of this enzyme class is aryl-aldehyde:oxygen oxidoreductase. JM; Sutherland, John B.; Pometto, Anthony L.; ... In enzymology, an aryl-aldehyde oxidase (EC 1.2.3.9) is an enzyme that catalyzes the chemical reaction an aromatic aldehyde + ... H2O2 The 3 substrates of this enzyme are aromatic aldehyde, O2, and H2O, whereas its two products are aromatic carboxylic acid ...

*Aldehyde dehydrogenase (NAD(P)+)

The systematic name of this enzyme class is aldehyde:NAD(P)+ oxidoreductase. Other names in common use include aldehyde ... This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ... In enzymology, an aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) is an enzyme that catalyzes the chemical reaction an aldehyde ... Black S (1951). "Yeast aldehyde dehydrogenase". Arch. Biochem. Biophys. 34 (1): 86-97. doi:10.1016/S0003-9861(51)80013-4. PMID ...

*Coniferyl-aldehyde dehydrogenase

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ... The systematic name of this enzyme class is coniferyl aldehyde:NAD(P)+ oxidoreductase. Achterholt S, Priefert H, Steinbuchel A ... In enzymology, a coniferyl-aldehyde dehydrogenase (EC 1.2.1.68) is an enzyme that catalyzes the chemical reaction coniferyl ... 2 H+ The 4 substrates of this enzyme are coniferyl aldehyde, H2O, NAD+, and NADP+, whereas its 4 products are ferulate, NADH, ...

*Alcohol dehydrogenase

... (NAD(P)+) Aldehyde dehydrogenase Oxidoreductase Blood alcohol content for rates of metabolism This ... leading to NADH and a zinc bound aldehyde or ketone Release of the product aldehyde. The mechanism in yeast and bacteria is the ... Finally, Ser-48 deprotonates the alcohol, making it an aldehyde. From a mechanistic perspective, if the enzyme adds hydride to ... Conway T, Ingram LO (Jul 1989). "Similarity of Escherichia coli propanediol oxidoreductase (fucO product) and an unusual ...

*Molybdopterin

... glyceraldehyde-3-phosphate ferredoxin oxidoreductase, respiratory arsenate reductase, carbon monoxide dehydrogenase, aldehyde ... Some oxidoreductases use tungsten in a similar manner as molybdenum by using it in a tungsten-pterin complex, with ... Tungsten-using enzymes typically reduce free carboxylic acids to aldehydes. The first tungsten-requiring enzyme to be ...
Multiple research groups have proposed crystal structures for the α2β2 tetrameric enzyme CODH/ACS from the acetogenic bacteria M. thermoacetica, including two recent examples since 2009: 3I01 2Z8Y. The two β units are the site of CODH activity and form the central core of the enzyme. In total, the 310 kDa enzyme contains seven iron-sulfur [4Fe-4S] clusters. Each α unit contains a single metal cluster. Together, the two β units contains five clusters of three types. CODH catalytic activity occurs at the Ni-[3Fe-4S] C-clusters while the interior [4Fe-4S] B and D clusters transfer electrons away from the C-cluster to external electron carriers such as ferredoxin. The ACS activity occurs in A-cluster located in the outer two α units.[2][3]. A noteworthy feature of the M.thermoacetica CODH/ACS is an internal gas tunnel connecting the multiple active sites.[6] The full role of the gas channel in regulating the rate catalytic activity is still a subject of investigation, but several studies ...
1FFU: The effect of intracellular molybdenum in Hydrogenophaga pseudoflava on the crystallographic structure of the seleno-molybdo-iron-sulfur flavoenzyme carbon monoxide dehydrogenase.
Description of disease Fatty aldehyde dehydrogenase deficiency. Treatment Fatty aldehyde dehydrogenase deficiency. Symptoms and causes Fatty aldehyde dehydrogenase deficiency Prophylaxis Fatty aldehyde dehydrogenase deficiency
Shop Alcohol-forming fatty acyl-CoA reductase ELISA Kit, Recombinant Protein and Alcohol-forming fatty acyl-CoA reductase Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
A 3.2 kb fragment of an indigenous Anabaena azollae plasmid was isolated and fully sequenced. Sequence analysis identified an open reading frame of 1110-bp that showed high similarity (56-71%) with glutathione dependent formaldehyde dehydrogenase genes (gdfaldh) from various bacteria. The identity of the gene was confirmed by expressing the gene in Escherichia coli with a pET-32 (a) vector followed by enzyme assay. Adjacent to the gdfaldh a second gene was detected that showed high similarity (53%) with an S-formylglutathione hydrolase (fgh) gene from the methylotrophic bacterium Paracoccus denitrificans. The presence of gdfaldh and fgh-like genes adjacent to each other may suggest that the corresponding gene products interact in a common metabolic pathway involved in removing exogenous or endogenous formaldehyde ...
Alcohol dehydrogenases (ADH) (EC 1.1.1.1) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In humans and many other animals, they serve to break down alcohols that otherwise are toxic, and they also participate in generation of useful aldehyde, ketone, or alcohol groups during biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+. Genetic evidence from comparisons of multiple organisms showed that a glutathione-dependent formaldehyde dehydrogenase, identical to a class III alcohol dehydrogenase (ADH-3/ADH5), is presumed to be the ancestral enzyme for the entire ADH family. Early on in evolution, an effective method for eliminating both endogenous and exogenous formaldehyde was important and this ...
Birds clean and lubricate their feathers with waxes that are produced in the uropygial gland, a holocrine gland located on their back above the tail. The type and the composition of the secreted wax esters are dependent on the bird species, for instance the wax ester secretion of goose contains branched-chain fatty acids and unbranched fatty alcohols, whereas that of barn owl contains fatty acids and alcohols both of which are branched. Alcohol-forming fatty acyl-CoA reductases (FAR) catalyze the reduction of activated acyl groups to fatty alcohols that can be esterified with acyl-CoA thioesters forming wax esters. cDNA sequences encoding fatty acyl-CoA reductases were cloned from the uropygial glands of barn owl (Tyto alba), domestic chicken (Gallus gallus domesticus) and domestic goose (Anser anser domesticus). Heterologous expression in Saccharomyces cerevisiae showed that they encode membrane associated enzymes which catalyze a NADPH dependent reduction of acyl-CoA thioesters to fatty alcohols. By
In contrast to the published description of S. mucosus [7], which suggests a strictly aerobic and chemoheterotrophic metabolism, the genome reveals an astonishing metabolic versatility. Besides genes for the degradation of organic substrates, we also found genes encoding enzymes for the utilization of alternative electron donors enabling facultative lithotrophic growth: a Sox multienzyme complex encoded by the genes salmuc_00587 - 00597 could be utilized for the oxidation of thiosulfate to sulfate, while molecular hydrogen may be utilized as electron donor by a multimeric uptake hydrogenase of the [NiFe]-type (salmuc_04814 - 04830). A further potential substrate is carbon monoxide, which might be oxidized by an aerobic-type carbon monoxide dehydrogenase encoded by the genes salmuc_05576 - 05578. Additional genes encoding subunits of carbon monoxide dehydrogenase were found dispersed at several sites in the genome. The metabolic plasticity of this species is further reflected in a multiple ...
The complexes feature a six-coordinate Mo(1) atom bridged to a four-coordinate Cu(1) atom via a single, bent μ-sulfido ligand S(1). The coordination sphere of Mo(1) contains a tridentate fac-TpiPr ligand and mutually cis, monodentate terminal oxo, phenolate and μ-sulfido ligands. The Mo(1) atoms lie ca. 0.28 Å out of the equatorial planes, defined by S(1), O(2), N(21) and N(31), towards the terminal oxo atom O(1). The major distortions from octahedral geometry include the deviation of the axial bond angles from 180° [O(1)-Mo(1)-N(11) ca. 162° for group 1 and 167° for 2] and acute TpiPr N-Mo-N angles (75-85°). The terminal oxo and phenoxide bond lengths, ranging from 1.673-1.698 Å and 1.972-2.009 Å, respectively, are typical of closely related structures.51 The Mo(1)-S(1) distances (av. 2.28 Å) are typical of values observed in Mo(μ-S)2Cu species (2.26-2.28 Å).28-34 The Mo-N distances are typical of oxosulfido-Mo-TpiPr species, the significant trans influence of the terminal oxo ...
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
Previous studies have shown that the steady state mRNA levels of RALDH2 are significantly increased during recovery from induced myopia.17 In the present study, RALDH2 protein expression was compared in 4-day control (C) and recovering (R) eyes by Western blot with chick specific anti-RALDH2 antibodies (Fig. 4A). The 4-day time point was used since RALDH2 mRNA levels were shown previously to be significantly increased at this time point.17 Quantification of the band intensities demonstrated that RALDH2 protein levels were significantly increased in 4-day recovering choroids (3.65 ± 0.45 RALDH2 IOD/8-mm punch) compared to controls (1.62 ± 0.31 RALDH2 IOD/8-mm punch; P , 0.05, paired t-test; n = 4) (Figs. 4A, 4B). RALDH2 protein expression in 8-mm posterior choroidal punches was examined subsequently at several time points throughout the recovery process (0 hours to 15 days; Fig. 5). RALDH2 was detected in control and recovering choroids at all time points examined as an approximately 55 kDa ...
Retinal Dehydrogenase: A metalloflavoprotein enzyme involved the metabolism of VITAMIN A, this enzyme catalyzes the oxidation of RETINAL to RETINOIC ACID, using both NAD+ and FAD coenzymes. It also acts on both the 11-trans- and 13-cis-forms of RETINAL.
3UKO: Crystal structure and kinetic behavior of alcohol dehydrogenase III /S-nitrosoglutathione reductase from arabidopsis thaliana
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
Complete information for FAR2P1 gene (Pseudogene), Fatty Acyl-CoA Reductase 2 Pseudogene 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
Anna was looking forward to receiving her third year trophy, and she was worried about what would happen to her partner in the show without her. Every co-dependent, desire-to-please/fix/make OK alarm sounded in my body; I wanted my girls there even if I was sweating it out and pushing George into the world at that very moment! I did not want to disappoint them... but if Emre was with me as labor coach, was that feasible? Practical? Prudent? Yes, I had a dance mom on standby, willing to come and pick them up and do their hair... but I dont know her well, neither do my girls, and while Anna would be old enough to handle this upheaval in stride, would little Gianna manage? What if one of them got hurt or fell ill while backstage? What to do!? My husband helped me to discern that I was stressing out over the possibility of separation; the actual separation into unchartered territory would create more anxiety for me during labor and that was exactly what I didnt need. Furthermore, my concerns were ...
Are you co-dependent or know someone who is? Are you not sure what co-dependency is and want to learn more | Breaking the Barriers of Co-Dependency on Cellas Chat | VoiceAmerica - The Leader in Internet Media
resume formate for images resume formate. Take the most recent Glamorous photos of resume formate tagged at stagedeguitare.com. 22-Jan-18 06:53:45
Looking for SPECTRUM Cyanomethyl Formate,5g (19HA94)? Graingers got your back. Price:$60.50. Easy ordering & convenient delivery. Log-in or register for your pricing.
Looking for online definition of retinaldehyde dehydrogenase 1 in the Medical Dictionary? retinaldehyde dehydrogenase 1 explanation free. What is retinaldehyde dehydrogenase 1? Meaning of retinaldehyde dehydrogenase 1 medical term. What does retinaldehyde dehydrogenase 1 mean?
Preparations of sheep liver cytoplasmic aldehyde dehydrogenase obtained by published methods were found by analytical isoelectric focusing in the pH range 5-8 to contain 5-10% by weight of the mitochondrial aldehyde dehydrogenase. Under the conditions used the pI of the cytoplasmic enzyme is 6.2 and that of the mitochondrial enzyme 6.6. The mitochondrial enzyme can be removed from the preparation by selective precipitation of the cytoplasmic enzyme with (NH4)2SO4. Kinetic experiments and inhibition experiments with disulfiram show that the properties of the two sheep liver enzymes are so different that the presence of 10% mitochondrial enzyme in preparations of the cytoplasmic enzyme can introduce serious errors into results. Our results suggest that the presence of 10 microM-disulfiram in assays may completely inactivate the pure cytoplasmic enzyme. This result is in contrast with a previous report [kitson (1978) Biochem. U. 175, 83-90]. ...
Introduction: Diminished NO production and altered NO bioavailability promote vascular inflammation and atherosclerosis. S-nitrosoglutathione reductase (GSNOR) controls cellular NO balance by degrading S-nitrosoglutathione (GSNO), which is a major source of nitric oxide (NO) bioactivity. GSNOR inhibition increases protein S-nitrosylation and potentiates NO action. The role of GSNOR in vascular inflammation is undefined, and the purpose of our investigation was to determine if GSNOR targeting dampens inflammation and reduces atherosclerosis.. Methods and results: We evaluated vascular inflammation and atherosclerosis in wild type (WT) and GSNOR-deficient (GSNOR-/-) mice. TNF-induced NFκB activation was reduced by 40% (p,0.05) in endothelial cells (ECs) isolated from GSNOR-/- compared to WT mice, which was accompanied by attenuated expression of P-selectin, E-selectin, and VCAM-1 (,34% reduction, p,0.05). Decreased EC adhesion molecule expression led to a 45% reduction in leukocyte rolling in the ...
Expression of alcohol-forming fatty acyl-CoA reductases in E. coli can result in the biosynthesis of fatty alcohols from endogenous E. coli fatty acids, but the levels were quite low [19]. To improve the production of fatty alcohols, Steen et al. carried out a further genetic modification of E. coli, and achieved an increased titer (~60 mg/L) of the medium chain fatty alcohols (C12 or C14 alcohols) [3]. In their strategy, they employed thioesterases with different substrate specificities to tailor the composition of the FFAs, and used the aldehyde-forming fatty acyl-CoA reductase Acr1 for the conversion of fatty acyl-CoAs to fatty aldehydes. The synthesized fatty aldehydes can be further converted to fatty alcohols by an unknown alcohol dehydrogenase/aldehyde reductase of E. coli [6].. However, Steen et al. just obtained a small quantity of C16/18 alcohol, though they used the thioesterase TesA, which was capable of yielding a large proportion of C16/18 FFA [3]. As aforementioned, expression of ...
Kinetic studies were carried out on mitochondrial aldehyde dehydrogenase (EC 1.2.1.3) isolated from sheep liver. Steady-state studies over a wide range of acetaldehyde concentrations gave a non-linear double-reciprocal plot. The dissociation of NADH from the enzyme was a biphasic process with decay constants 0.6s-1 and 0.09s-1. Pre-steady-state kinetic data with propionaldehyde as substrate could be fitted by using the same burst rate constant (12 +/- 3s-1) over a wide range of propionaldehyde concentrations. The quenching of protein fluorescence on the binding of NAD+ to the enzyme was used to estimate apparent rate constants for binding (2 × 10(4) litre.mol-1.s-1) and dissociation (4s-1). The kinetic properties of the mitochondrial enzyme, compared with those reported for the cytoplasmic aldehyde dehydrogenase from sheep liver, show significant differences, which may be important in the oxidation of aldehydes in vivo. ...
Mono- and Stereopictres of 5.0 Angstrom coordination sphere of Potassium atom in PDB 2wme: Crystallographic Structure of Betaine Aldehyde Dehydrogenase From Pseudomonas Aeruginosa
TY - JOUR. T1 - Levels of retinoic acid and retinaldehyde dehydrogenase expression in eyes of the Mitf-vit mouse model of retinal degeneration.. AU - Duncan, T.. AU - Swint, C.. AU - Smith, S. B.. AU - Wiggert, B. N.. PY - 1999/6/28. Y1 - 1999/6/28. N2 - PURPOSE: Several reports have characterized the retinal degeneration observed in the Mitf(vit) mutant mouse. Despite these reports, the factor(s) that may cause or modulate the degeneration still are not well defined; however, it is known that the photoreceptors of Mitf(vit) mice die through an apoptotic mechanism. We reported previously that retinoid metabolism in the RPE of Mitf(vit)++ mice is perturbed. Retinoids regulate genes via the RAR and RXR nuclear receptor pathway that are involved in numerous cellular responses including apoptosis. It is possible that retinoic acid (RA) modulates the retinal degeneration observed in the Mitf(vit) mice. The purpose of this study was to evaluate the levels of RA in whole eyes, as well as its ...
In 1957, Sjögren and Larsson described a cohort of Swedish patients with an unusual combination of symptoms that included of congenital ichthyosis, intellectual disability, and spastic diplegia or tetraplegia. Family studies indicated that Sjögren-Larsson syndrome (SLS) was a genetic disorder with autosomal recessive inheritance.
RALDH2, RALDH 2, RALDH(II), aldehyde dehydrogenase 1A2, aldehyde dehydrogenase family 1 member A2, retinal dehydrogenase 2, retinaldehyde dehydrogenase 2, retinaldehyde-specific dehydrogenase type 2, Retinal dehydrogenase 2, RALDH 2, Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type ...
Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
The invention provides a method of chemically-mechanically polishing a substrate comprising tungsten through use of a composition comprising a tungsten etchant, an inhibitor of tungsten etching, and water, wherein the inhibitor of tungsten polishing is a polymer, copolymer, or polymer blend comprising at least one repeating group comprising at least one nitrogen-containing heterocyclic ring or a tertiary or quaternary nitrogen atom. The invention further provides a chemical-mechanical polishing composition particularly useful in polishing tungsten-containing substrates.
Betaine aldehyde dehydrogenase (BADH) is important enzyme which plays a dual role in cereals. It acts as an osmoprotectant and has an important role during abiotic stress. In addition it also influences the fragrance in rice. Therefore, this gene has both agronomical and breeding values. An 8pb deletion in exon 7 cause a premature termination codon in BADH2 resulting a mutate badh2 allele; which ultimately elevates the level of 2AP leading fragrance in fragrant rice (Bradbury et al., 2008). Unlike rice wheat is a hexaploid and has two BADH homologs i.e. BADH1 and BADH2. Our genomic data shows that there are three alleles for BADH homologs. One allele is present in the progenitors and these indicates that, these allele is inheritate from each of the progenitors during polyploidy in hexaploid wheat. Our data show that a total of 4 and 14 SNPs are present among the genomes in BADH2 and BADH1respectivly. Investigation on two different tissues (i.e. leaves and seeds), at two different time point (i.e. 14 DPA
S-hydroxymethylglutathione dehydrogenase from Paecilomyces variotii No. 5 strain (NBRC 109023), isolated as a formaldehyde-degrading fungus, was purified by a procedure that included ammonium sulfate precipitation, DEAE-Sepharose and hydroxyapatite chromatography and isoelectrofocusing. Approximately 122-fold purification was achieved with a yield of 10.5%. The enzyme preparation was homogeneous as judged by sodium dodecyl polyacrylamide gel electrophoresis (SDS-PAGE). The molecular mass of the purified enzyme was estimated to be 49 kDa by SDS-PAGE and gel filtration, suggesting that it is a monomer. Enzyme activity was optimal at pH 8.0 and was stable in the range of pH 7.0-10. The optimum temperature for activity was 40°C and the enzyme was stable up to 40°C. The isoelectric point was pH 5.8. Substrate specificity was very high for formaldehyde. Besides formaldehyde, the only aldehyde or alcohol tested that served as a substrate was pyruvaldehyde. Enzyme activity was enhanced by several divalent
Supported Au catalysts have been studied extensively for CO oxidation. These catalysts are known to catalyze this reaction even at sub-ambient temperatures. While recent literature demonstrates catalytic activity of gold nanoparticles |2 |nm, the next stage in fine tuning this catalysis process is to develop gold clusters prepared with atomic precision. Such atomically precise gold catalysts supported on TiO2 hitherto have not been investigated for CO oxidation. The main objective of this work is to synthesize atomically-precise Au38 clusters in a flask-based method using principles of wet chemistry, to characterize these clusters using various advanced spectroscopic techniques, and to test these clusters as potential catalytic materials for CO oxidation. Furthermore, we have tested TiO2-supported Au38 clusters and a commercially purchased Au/TiO2 catalyst for CO oxidation at 30 °C and 60 °C, and used DRIFTS as a probe spectroscopic technique to correlate kinetics with the mechanism occurring on the
ID ADHE_ECOLI Reviewed; 891 AA. AC P0A9Q7; P17547; DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 2. DT 22-NOV-2017, entry version 109. DE RecName: Full=Aldehyde-alcohol dehydrogenase; DE Includes: DE RecName: Full=Alcohol dehydrogenase; DE Short=ADH; DE EC=1.1.1.1; DE Includes: DE RecName: Full=Acetaldehyde dehydrogenase [acetylating]; DE Short=ACDH; DE EC=1.2.1.10; DE Includes: DE RecName: Full=Pyruvate-formate-lyase deactivase; DE Short=PFL deactivase; GN Name=adhE; Synonyms=ana; OrderedLocusNames=b1241, JW1228; OS Escherichia coli (strain K12). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Escherichia. OX NCBI_TaxID=83333; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 2-11. RX PubMed=2695398; DOI=10.1016/0378-1119(89)90483-6; RA Goodlove P.E., Cunningham P.R., Parker J., Clark D.P.; RT "Cloning and sequence analysis of the fermentative alcohol- RT dehydrogenase-encoding gene of ...
Interest in the biochemistry of nickel has been stimulated by recent discoveries of its essentiality to various microorganisms, plants, and animals and of the existence of several nickel metalloenzymes in plants and microorganisms. Signs of nickel deprivation have been described for six animal species-chick, cow, goat, minipig, rat, and sheep. Included among the more consistent signs of deficiency in mammals are depressed growth, unthriftiness characterized by rough hair coat, and an altered iron metabolism leading to depressed hematopoiesis. The predominant sign of nickel deficiency for microorganisms is depressed growth, and for plants is depressed nitrogen utilization. In plants and microorganisms, nickel is known to function in several metalloenzymes including urease, several hydrogenases, and carbon monoxide dehydrogenase. In higher animals, the evidence showing that nickel is essential has not defined its metabolic function. The finding of nickel metalloenzymes in lower forms of life ...
GenBank) aldehyde-alcohol dehydrogenase 2 [Includes: Alcohol dehydrogenase (EC 1.1.1.1) (ADH); Acetaldehyde dehydrogenase (ACDH ...
J:104523 Ribes V, Wang Z, Dolle P, Niederreither K, Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling. Development. 2006 Jan;133(2):351-61 ...
Antabuse, also called disulfiram, is a famous drug for the treatment of alcohol and drug addiction. Its working mechanism is based on inhibition of the acetaldehyde dehydrogenase (the enzyme responsible for the split of acetaldehyde- the enzyme, which helps to digest alcohol.
Further information can be found in the Supplemental Methods.. Animals. Mice were housed in a pathogen-free, temperature- and light-controlled animal facility under a 12-hour light/dark cycle. ALDH2-/- LDLR-/- mice were obtained by crossing ALDH2-/- mice (a gift from Jun Ren and Aijun Sun, Zhongshan Hospital affiliated with Fudan University, Shanghai, China) (37, 40) and LDLR-/- mice (Jackson Laboratory). ALDH2-/-APOE-/- mice were obtained by crossing ALDH2-/- mice and APOE-/- mice (Shanghai Model Organisms). All mice used in the present study were on a C57BL/6 background. For atherosclerotic study, 6-week-old mice were fed Western Diet (Research Diets, catalog D12079B) for 12 weeks or 26 weeks (26-week experiment was done in duplicate). The number of mice studied in each experiment is shown in the figure legends.. Cell culture. HEK 293T cell lines were purchased from the CAS Cell Bank and cultured in DMEM containing 10% FBS. Isolation of bone marrow-derived macrophages (BMDMs) followed a ...
Semantic Scholar extracted view of Aldehyde dehydrogenase activity and level of dopamine in certain sections of the brain of rats preferring and refusing ethanol by Kharchenko Nk
Sjögren-Larsson syndrome presents with ichtyosis, spastic diplegia and cognitive deficits. It is caused by a deficiency of fatty aldehyde dehydrogenase. Treatments are limited to symptomatic therapies; for example, ziluteon (an inhibitor of 5-lipoxygenase) can reduce pruritus.. In a recent article, bezafibrate has been shown to induce the expression of the deficient protein in fibroblasts from some patients. This discovery could become of clinical importance ...
FUJIWARA Ken , DAVAADASH Bulgan , YATABE Megumi , KIKUCHI Motoshi , HORIGUCHI Kotaro , KUSUMOTO Kenji , KOUKI Tom , YASHIRO Takashi Medical molecular morphology : official journal of the Japanese Society for Clinical Molecular Morphology 41(3), 126-131, 2008-09-01 医中誌Web 参考文献20件 ...
Aldehyde dehydrogenase 10山羊多克隆抗体(ab103902)可与小鼠, 大鼠样本反应并经WB实验严格验证。所有产品均提供质保服务,中国75%以上现货。
Principal nameFormate dehydrogenase antibodyAlternative names for Formate dehydrogenase antibodyFDH1, FDH, FDH3, NAD-dependent formate…
Or ALDH, this breaks down various aldehydes into the corresponding carboxylic acids. Its most notable substrate is, of course ethanal the breakdown prod...
Réactivité: Boeuf (Vache), Chien, Cobaye and more. Comparez ALDH1A2 Anticorps. Commandez directement chez anticorps-enligne.fr.
How is Gomoris aldehyde fuchsin-Alcian blue combination abbreviated? GAF-AB stands for Gomoris aldehyde fuchsin-Alcian blue combination. GAF-AB is defined as Gomoris aldehyde fuchsin-Alcian blue combination rarely.
Homo sapiens aldehyde dehydrogenase 18 family, member A1 (ALDH18A1), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA. (H00005832-R03) - Products - Abnova
Objective: To study cortical excitability, electroencephalography patterns, nerve conduction velocity, and sleep patterns, in succinic semialdehyde dehydrogenase (SSADH) deficiency, a rare autosomal recessive pediatric neurotransmitter disease associated with elevated levels of brain gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter. The clinical phenotype includes mental retardation, epilepsy, and neuropsychiatric manifestations.. Study Population: Patients with SSADH deficiency, parents of patients (who are obligate heterozygotes), and healthy volunteers.. Design: This is a natural history study in which subjects will have a series of neurophysiological tests. Transcranial magnetic stimulation (TMS) is a non-invasive technique that allows for measures of cortical excitation and inhibition. Electroencephalography (EEG) measures baseline brain electrical activity. Nerve conduction studies measure the speed of conduction of impulses by peripheral nerves. Polysomnography ...
The retina often has glistening white intraretinal dots which may be concentrated in the macula. They have been found in 1 to 2 year old infants. The macula may have punched out lesions. A pigmentary retinopathy is present in about 50% of patients and fluorescein angiography reveals a mottled hyperfluorescence. The cornea often has grayish stromal opacities that become vascularized, most commonly in the lower half. Most patients have punctate keratitis resulting in marked photophobia. Visual acuities can range from about 20/40 to finger counting. The retinal changes may be progressive but EOG and ERG studies do not reveal abnormalities of retinal function. VEPs though are often abnormal. Ichthyosis may involve the lids and periorbital areas.. ...
Looking for online definition of Aldehyde Dehydrogenase 5 Family, Member A1 in the Medical Dictionary? Aldehyde Dehydrogenase 5 Family, Member A1 explanation free. What is Aldehyde Dehydrogenase 5 Family, Member A1? Meaning of Aldehyde Dehydrogenase 5 Family, Member A1 medical term. What does Aldehyde Dehydrogenase 5 Family, Member A1 mean?
ALDH2.2; aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2; aldh2; cb154; aldh2b; aldh2l; zgc:85659; wu:fi26c02; aldehyde dehydrogenase 2b; aldehyde dehydrogenase 2.2; aldehyde dehydrogenase 2, like; aldehyde dehydrogenase 2, tandem dupl ...
RN [1] RM 96134964 RT Characterization of the cdhD and cdhE genes encoding subunits of the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex from Methanosarcina thermophila. RA Maupin-Furlow J, Ferry JG RL J Bacteriol 1996 Jan;178(2):340-6 RN [2] RT Cloning and expression of the gene cluster encoding key proteins involved in acetyl-CoA synthesis in Clostridium thermoaceticum: CO dehydrogenase, the corrinoid/Fe-S protein, and methyltransferase. RA Roberts DL, James-Hagstrom JE, Garvin DK, Gorst CM, Runquist JA, Baur JR, Haase FC, Ragsdale SW RL Proc Natl Acad Sci U S A 1989 Jan;86(1):32-6 SE TIGR GA hmmls AL clustalw, belvu DR HAMAP; MF_01135; 9 of ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Despite not accumulating glycine betaine, rice (Oryza sativa) possesses two genes encoding betaine aldehyde dehydrogenase (BADH, EC 1.2.1.8) (BADH1 and BADH2). A BADH2 allele which codes for a truncated BADH2 enzyme is responsible for the elevated level of 2-acetyl-1-pyrroline (2AP) which gives Jasmine and Basmati style fragrant rices their distinct aroma. In this study the transcript levels of the genes which encode BADH1 and BADH2 were studied using quantitative reverse-transcriptase PCR (qRTPCR) in multiple fragrant and non-fragrant rice varieties. In non-fragrant rices, BADH2 transcript levels were significantly higher than those of BADH1 in leaf and mature seed, whilst in developing seed BADH1 and BADH2 transcript levels were similar. This indicates that the loss of BADH2 activity due to the deletion in the gene in fragrant rice is likely to result in a significant reduction in total functional BADH. BADH2 transcript levels in non-fragrant rice varieties were significantly higher than the levels in
Goat anti Human aldehyde dehydrogenase 1 antibody recognizes aldehyde dehydrogenase 1 family, member A1, also known as ALDH1A1. Goat anti
CO Oxidation over Pd-ZrO2 Catalysts: Role of Support′s Donor Sites. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
The surface structure of Pd(100) during CO oxidation was measured using a combination of a flow reactor and in situ surface X-ray diffraction coupled to a large-area 2-dimensional detector. The surface structure was measured for PO2/PCO ratios between 0.6 and 10 at a fixed total gas pressure of 200 mbar and
A Kyushu University-led collaboration developed a catalyst that can oxidize both hydrogen and carbon monoxide in fuel cells. As a result, their catalyst is resistant to poisoning by the contaminant carbon monoxide in commercial hydrogen gas, which is a common limitation of current fuel cell catalysts. The action of the multifunctional catalyst resembled that of two enzymes: a hydrogenase and carbon monoxide dehydrogenase. This catalyst is promising for use in high-performance hydrogen fuel cells.
Identification of Crucial Amino Acids in Mouse Aldehyde Oxidase 3 That Determine Substrate Specificity. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Retinaldehyde Serum is ideal for normal to dry, aging skin and helps correct hyperpigmentation, sun damage, congestion, roughness and thin or sensitive skin.
Definition of retinaldehyde isomerase. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
A free platform for explaining your research in plain language, and managing how you communicate around it - so you can understand how best to increase its impact.
We,China ALDEHYDE C18 104-61-0 Suppliers and China ALDEHYDE C18 104-61-0 Manufacturers, provide ALDEHYDE C18 104-61-0 product and the products related with China ALDEHYDE C18 104-61-0 - winsunchem
When you heal a co-dependent relationship, usually by ending it, you may go through an identity crisis. Be prepared to see and become who you really are. Maybe you wont be the cute, innocent, docile creature you think you are. This has to be okay with you. Better to be genuine. Many, many people have terrible fears that if they say what is on their mind, if they behave like they feel like behaving toward another, if they dropped their props and phony mannerisms, they will be rejected and scorned by their partners or by the world. It is not so!!! Real people will respect you more, and like you more. The only ones who will not like are the other co-dependent types, who are themselves putting on an act and do not want you to break their spell - often the spell they have over you. ...
In many bacteria, plants and animals, the osmoprotectant betaine is synthesized in two steps: (1) choline to betaine aldehyde and (2) betaine aldehyde to betaine ...
We,China 4-Methylthiazole-5-aldehyde 82294-70-0 Suppliers and China 4-Methylthiazole-5-aldehyde 82294-70-0 Manufacturers, provide 4-Methylthiazole-5-aldehyde 82294-70-0 product and the products related with China 4-Methylthiazole-5-aldehyde 82294-70-0 - Shandong Sihuan
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
Mollusks and human are different species, but because of convergent evolution that led them to have similar genetic expression. There have been studies that proved octopus eyes are similar to humans. In their study, they used a set of 1052 genes of the octopus eye and 13 303 genes of the human eye. For one of the research, they discovered that the protein in the eye were similar. When then compared the genes, they identified that a total of 729 genes were commonly expressed, a total of 69.3%. On other various tests,they found that six3, lhx2, retinal arrestin, retinal dehydrogenase, and human nuclear-transport receptor karyopherin were found to be expressed in the octopus eye ...
Tinku Baidya, Gargi Dutta, M. S. Hegde and Umesh V. Waghmare, Noble metal ionic catalysts: correlation of increase in CO oxidation activity with increasing effective charge on Pd ion in Pd ion substituted Ce1-xMxO2-d (M = Ti, Zr and Hf), Dalton Trans. 455 - 464 (2009 ...
Thiolate Ligands as a Double-Edged Sword for CO Oxidation on CeO2 Supported Au25(SCH2CH2Ph)18 Nanoclusters", Z. Wu, D.-e. Jiang, A. K. P. Mann, D. R. Mullins, Z.-A. Qiao, L. F. Allard, C. Zeng, R. Jin, and S. H. Overbury. J. Am. Chem. Soc. 2014, 136, 6111-6122 ...
Guidchem offer qualified suppliers for Octyl aldehyde (CAS NO.124-13-0) ,Find latest products of Octyl aldehyde manufacturers, suppliers, exporters and producers on guidechem.com.
Residues 1 to 131 (E-value = 9.7e-37) place NG1997 in the Semialdhyde_dh family which is described as Semialdehyde dehydrogenase, NAD binding domain (PF01118 ...
Find out about the science and chemistry of Formaldehyde (Methanal ), see colourful images of Formaldehyde and explore interactive 3D molecules of Formaldehyde
Acetaldehyde; formaldehyde/ACM68442604 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum…
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum…
In recent years, aldehyde oxidase (AO) has continued to grow as an important enzyme in drug metabolism. Herein, we have focused primarily on the inhibition kinetics of AO and also developing tools to better understand AO ...
SpillKit Formaldehyde | Emergency cleaning set • Reliable protection for a safe removal of formaldehyde • Keeping you well equipped for accidents involving formaldehyde
Hope every expert will be fine. i want to get current date and time in the formate like this 04/15/2002 05:25:45 PM or 04/15/2002 05:25:45 tell me simple way because I am new in VC++. waiting for...
Testul de identificare specie: Examen microscopic nativ si colorat, cultură și identificare fungica. Proba de sensibilitate la antifungice Probe din: Exsudat Faringian. ...
Testul de identificare specie: Examen microscopic nativ si colorat, cultură și identificare fungica. Proba de sensibilitate la antifungice Probe din: Secretii otice. ...
Hier könnt ihr euch eine Übersicht über alle aktuell verfügbaren Klartext-Stempel zum Ausdrucken auf DIN-A4 herunterladen (auch super geeignet als Inventur- oder Wunschliste!): ...
Succinic semialdehyde dehydrogenase deficiency (SSADHD), also known as 4-hydroxybutyric aciduria or gamma-hydroxybutyric aciduria, is a rare autosomal recessive disorder of the degradation pathway of the inhibitory neurotransmitter γ-aminobutyric acid, or GABA. The disorder has been identified in approximately 350 families, with a significant proportion being consanguineous families. The first case was identified in 1981 and published in a Dutch clinical chemistry journal that highlighted a person with a number of neurological conditions such as delayed intellectual, motor, speech, and language as the most common manifestations. Later cases reported in the early 1990s began to show that hypotonia, hyporeflexia, seizures, and a nonprogressive ataxia were frequent clinical features as well. SSADH deficiency is caused by an enzyme deficiency in GABA degradation. Under normal conditions, SSADH works with the enzyme GABA transaminase to convert GABA to succinic acid. Succinic acid can then be ...
The study will consist of a clinical component and a scientific component consisting of laboratory investigations of potentially useful biochemical (lipid and protein) markers. Up to 50 SLS patients of all ages, gender and ethnic origins will be enrolled. A detailed clinical evaluation will be performed to determine the presence and extent of disease involving the skin, nervous system and eyes. Clinical testing will include brain magnetic resonance imaging (MRI) and spectroscopy (MRS), electroencephalography (EEG), neurocognitive tests, ophthalmologic examination with retinal photographs and optical coherence tomography (OCT), photographs of the skin and tests of cutaneous transepidermal water loss. Laboratory investigations will include lipid analyses (e.g. fatty alcohols, farnesol, fatty acids, ether glycerolipids, etc.) of blood, skin and urine; proteomic analysis of skin (stratum corneum); and measurements of leukocyte fatty alcohol and farnesol oxidation. A skin biopsy (optional) will be ...
Aldehyde dehydrogenases (ALDH, EC 1.2.1.3) are a group of enzymes that catalyze the oxidation (dehydrogenation) of aldehydes to carboxylic acids, an action also performed by xanthine oxidase (XO) and aldehyde oxidase (AO).. The aldehyde cinnamaldehyde commonly used as a food flavoring is rapidly oxidized by aldehyde dehydrogenases into the carboxylic acid cinnamic acid.. ...
AIM: Pathological gambling and comorbid alcohol dependence often occur in combination. Disulfiram is one of the proven drugs for alcohol dependence. In addition to its inhibiting acetaldehyde dehydrogenase, disulfiram inhibits dopamine beta-hydroxyla
This project is supported by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canadas national genomics strategy with $900 million in funding from the federal government ...
Aldehyde dehydrogenases in rat brain: subcellular distribution, properties and involvement in acetaldehyde and dopamine metabolism ...
Aliphatic aldehydes of the general formula I ##STR1## where R.sup.1 is hydrogen or methyl,R.sup.2 is a straight-chain or branched alkyl radical of 1 to 4 carbon atoms and the two radicals X are each hydrogen or together form a further C--C bond, in particular2,5,7,7-tetramethyloctanal,2,4,5,7,7-pentamethyloctanal,2-ethyl-5,7,7-trimethyloctanal and2,5,7,7-tetramethyl-2-octen-1-al, are used in scent compositions and are prepared by a process in which an aldehyde of the general formula II ##STR2## is condensed with an aldehyde of the general formula III ##STR3## in the presence of an aldol condensation catalyst to give the substituted octenal of the general formula I, and, if required, the latter is partially hydrogenated or reduced to give the ocorresponding octanal of the formula I.
Aldehyde oxidases (AOXs) are molybdoflavoenzymes with an important role in the metabolism and detoxification of heterocyclic compounds and aliphatic as well as aromatic aldehydes. The enzymes use oxygen as the terminal electron acceptor and produce reduced oxygen species during turnover. Four different enzymes, mAOX1, mAOX3, mAOX4, and mAOX2, which are the products of distinct genes, are present in the mouse. A direct and simultaneous comparison of the enzymatic properties and characteristics of the four enzymes has never been performed. In this report, the four catalytically active mAOX enzymes were purified after heterologous expression in Escherichia coli. The kinetic parameters of the four mouse AOX enzymes were determined and compared with the use of six predicted substrates of physiologic and toxicological interest, i.e., retinaldehyde, N1-methylnicotinamide, pyridoxal, vanillin, 4-(dimethylamino)cinnamaldehyde (p-DMAC), and salicylaldehyde. While retinaldehyde, vanillin, p-DMAC, and ...
Butyraldehyde definition, a clear, colorless, flammable liquid, C 4 H 8 O, used chiefly as an intermediate in the manufacture of resins and rubber cement. See more.
View mouse Aldh7a1 Chr18:56509687-56572951 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
Sigma-Aldrich offers abstracts and full-text articles by [Kwok Ki Ho, Abhijit Mukhopadhyay, Yi Feng Li, Soma Mukhopadhyay, Henry Weiner].
A novel preparation of [email protected] and Au/Cd-ZnO structures is reported. The different morphologies of the two nanostructures are the result of either multiple or single nucleation events depending on the crystalline nature of the Au or Au/Cd seeds. Both samples are surprisingly active for CO oxidation and the water-gas
ALDH1A2 - ALDH1A2 (untagged)-Human aldehyde dehydrogenase 1 family, member A2 (ALDH1A2), transcript variant 2 available for purchase from OriGene - Your Gene Company.
Although aldehyde dehydrogenase (ALDH) from sheep liver cytosol has a broad specificity, it will not oxidize the aldehyde group of glyoxylic acid which is in fact an inhibitor of the enzyme. The inhibition pattern is non-linear but competitive at high propionaldehyde concentrations (2-20 mM); however, a simple non-competitive pattern is observed at low (less than 100 microM) propionaldehyde concentrations (Ki = 1.6 mM). The esterase activity was unaffected by glyoxylic acid in the absence of NAD+ but a simple competitive inhibition pattern (Ki = 2.5 mM) was observed with respect to 4-nitrophenyl acetate in the presence of NAD+. The data require a two-site model in which ester and aldehyde binding sites are distinct but with a second propionaldehyde molecule, and glyoxylic acid, binding at or near the ester binding site. Consistent with this model is the fact that chloral hydrate was a non-competitive inhibitor of the esterase activity in the presence of NAD+ but a competitive inhibitor in its ...
TY - JOUR. T1 - Order and disorder in mitochondrial aldehyde dehydrogenase. AU - Hurley, Thomas. AU - Perez-Miller, Samantha. AU - Breen, Heather. PY - 2001/1/30. Y1 - 2001/1/30. N2 - One of the most notable and currently unexplained features of the mitochondrial form of aldehyde dehydrogenase is its property of half-of-the-sites reactivity. An appropriate description of this phenomenon can be to consider this as the extreme example of negative cooperativity. This implies, therefore, that a pathway of communication must exist between active sites in order to convey the structural consequences of ligand binding. Data from four different structures of human ALDH2 collected during the past 2 years may shed some light on one possible pathway for the propagation of structural information. We recently published a 2.6 Å structure of a binary complex between ALDH2 and NAD+ in which the predominant conformation of the cofactor differed between different subunits in the structure. We now have three ...
Synopsis of Fatty Alcohol Alkoxylates Market. Fatty alcohol alkoxylates (FAA) is a class of non-ionic surfactants, which is readily biodegradable in nature with minimal toxicity as compared to its counterparts. It is mainly produced by the alkoxylation of fatty alcohols with addition of ethylene oxide (EO) and propylene oxide (PO). Fatty alcohol alkoxylates have a wide range of applications such as wetting agents, emulsifiers, and dispersion applications among others and it is consumed across an array of industries viz., household cleaning, industrial & institutional cleaning, detergent intermediates, textile, and personal care among others for the latter applications. Fatty alcohols from the natural and synthetic production routes are used in the preparation of fatty alcohol alkoxylates. On the basis of carbon chain distribution in each type of fatty alcohol alkoxylates, it is used for different applications across different industries. For instance, the long chain alcohol alkoxylates such as ...
Isolation and Characterization of a New Methanobacterium formicicum KOR-1 from an Anaerobic Digester Using Pig Slurry - Methanogen;Anaerobic Digester;16S rRNA;mcrA;Methanobacterium formicicum;
Define propionaldehyde. propionaldehyde synonyms, propionaldehyde pronunciation, propionaldehyde translation, English dictionary definition of propionaldehyde. n. A flammable liquid, C3H6O, with a suffocating odor, used in the manufacture of plastics and rubber chemicals, and as a preservative and disinfectant....

Tungsten-containing aldehyde oxidoreductasesTungsten-containing aldehyde oxidoreductases

Three different types of tungsten-containing aldehyde oxidizing enzymes aldehyde ferredoxin oxidoreductase (AOR), formaldehyde ... Detailed kinetic analyses of FOR indicate that C4 - C6 dialdehyde or acid-substituted aldehyde may serve as the physiological ... ferredoxin oxidoreductase (FOR) and glyceraldehyde-3-phosphate ferredoxin oxidoreductase (GAPOR) have previously been isolated ...
more infohttps://athenaeum.libs.uga.edu/handle/10724/20424

Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily (IPR036503) | InterPro | EMBL-EBIAldehyde ferredoxin oxidoreductase, N-terminal domain superfamily (IPR036503) | InterPro | EMBL-EBI

Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily (IPR036503). Short name: Ald_Fedxn_OxRdtase_N_sf ... Enzymes of the aldehyde ferredoxin oxidoreductase (AOR) family [PMID: 9242907] contain a tungsten cofactor and an 4Fe4S cluster ... Structure of a hyperthermophilic tungstopterin enzyme, aldehyde ferredoxin oxidoreductase.. Science 267 1463-9 1995 ... formaldehyde ferredoxin oxidoreductase (FOR), glyceraldehyde-3-phosphate ferredoxin oxidoreductase (GAPOR), all isolated from ...
more infohttps://www.ebi.ac.uk/interpro/entry/IPR036503

ECMDB: aldehyde oxidoreductase, ethanolamine utilization protein (P77445)ECMDB: aldehyde oxidoreductase, ethanolamine utilization protein (P77445)

eco:b2455 eutE; aldehyde oxidoreductase, ethanolamine utilization protein; K04021 aldehyde dehydrogenase (N) ... eco:b2455 eutE; aldehyde oxidoreductase, ethanolamine utilization protein; K04021 aldehyde dehydrogenase (A) ... aldehyde oxidoreductase, ethanolamine utilization protein (P77445). Identification. Name:. aldehyde oxidoreductase, ...
more infohttp://ecmdb.ca/proteins/P77445

Aldehyde ferredoxin oxidoreductase - WikipediaAldehyde ferredoxin oxidoreductase - Wikipedia

In enzymology, an aldehyde ferredoxin oxidoreductase (EC 1.2.7.5) is an enzyme that catalyzes the chemical reaction an aldehyde ... Aldehyde Ferredoxin Oxidoreductase is a member of an AOR family, which includes glyceraldehyde-3-phosphate ferredoxin ... The systematic name of this enzyme class is aldehyde:ferredoxin oxidoreductase. This enzyme is also called AOR. It is a ... Roy R, Dhawan IK, Johnson MK, Rees DC, Adams MW (2006-04-15). Handbook of Metalloproteins: Aldehyde Ferredoxin Oxidoreductase ( ...
more infohttps://en.wikipedia.org/wiki/Aldehyde_ferredoxin_oxidoreductase

NAVER Academic | Aldehyde oxidoreductase as a biocatalyst: Reductions of vanillic acidNAVER Academic | Aldehyde oxidoreductase as a biocatalyst: Reductions of vanillic acid

ATP and NADPH dependent reduction of carboxylic acids to their corresponding aldehydes. The identification of the gene from ... Aldehyde oxidoreductase (carboxylic acid reductase) catalyzes the Mg 2+, ... Aldehyde oxidoreductase as a biocatalyst: Reductions of vanillic acid. Author. Venkitasubramanian Padmesh, Daniels Lacy, Das ... Aldehyde oxidoreductase (carboxylic acid reductase) catalyzes the Mg 2+, ATP and NADPH dependent reduction of carboxylic acids ...
more infohttp://academic.naver.com/article.naver?doc_id=64814343

Kinetic and structural studies of aldehyde oxidoreductase from Desulfovibrio gigas reveal a dithiolene-based chemistry for...Kinetic and structural studies of aldehyde oxidoreductase from Desulfovibrio gigas reveal a dithiolene-based chemistry for...

The XO family member aldehyde oxidoreductase from Desulfovibrio gigas (DgAOR) is an exception as presents in its catalytically ... Kinetic and structural studies of aldehyde oxidoreductase from Desulfovibrio gigas reveal a dithiolene-based chemistry for ... Kinetic and structural studies of aldehyde oxidoreductase from Desulfovibrio gigas reveal a dithiolene-based chemistry for ... Mononuclear Mo-containing enzymes of the xanthine oxidase (XO) family catalyze the oxidative hydroxylation of aldehydes and ...
more infohttps://ri.conicet.gov.ar/handle/11336/494

Aldehyde oxidase as a cell marker for internal organs in Drosophila melanogaster.  - PubMed - NCBIAldehyde oxidase as a cell marker for internal organs in Drosophila melanogaster. - PubMed - NCBI

Aldehyde Oxidoreductases. LinkOut - more resources. Medical. *Genes and Gene Therapy - MedlinePlus Health Information ... Aldehyde oxidase as a cell marker for internal organs in Drosophila melanogaster.. Janning W. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/4632933?dopt=Abstract

Energies  | Free Full-Text | Microbial Conversion of Waste Glycerol from Biodiesel Production into Value-Added Products | HTMLEnergies | Free Full-Text | Microbial Conversion of Waste Glycerol from Biodiesel Production into Value-Added Products | HTML

... aldehyde oxidoreductase; DHAK, dihydroxyacetone kinase; FHL, formate hydrogen lyase complex; FRD, fumarate reductase; GlyD, ... aldehyde oxidoreductase; DHAK, dihydroxyacetone kinase; FHL, formate hydrogen lyase complex; FRD, fumarate reductase; GlyD, ... Zhang, Y.; Li, Y.; Du, C.; Liu, M.; Cao, Z. Inactivation of aldehyde dehydrogenase: A key factor for engineering 1,3- ... By inactivating aldehyde dehydrogenase (ADH), the enzyme responsible for ethanol formation in K. pneumoniae YMU2, less ethanol ...
more infohttps://www.mdpi.com/1996-1073/6/9/4739/htm

KEGG ENZYME: 1.2.99.7KEGG ENZYME: 1.2.99.7

Oxidoreductases;. Acting on the aldehyde or oxo group of donors;. With unknown physiological acceptors. ... Aldehyde oxidoreductase activity in Desulfovibrio alaskensis NCIMB 13491 EPR assignment of the proximal [2Fe-2S] cluster to the ... Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from ... Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas. ...
more infohttps://www.genome.jp/dbget-bin/www_bget?ec:1.2.99.7

Cryo-electron microscopy of AMD plasma cells with putat | Open-iCryo-electron microscopy of AMD plasma cells with putat | Open-i

Aldehyde Oxidoreductases/genetics. *Amino Acids/biosynthesis. *Cell Wall/metabolism. *Drug Resistance/genetics ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC3750248_1471-2164-14-485-5&req=4

Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4...Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4...

Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4- ... Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4- ... Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4- ... Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4- ...
more infohttp://www.biochemj.org/content/329/3/469

IJMS | Free Full-Text | Insight into Conformational Change for 14-3-3σ Protein by Molecular Dynamics SimulationIJMS | Free Full-Text | Insight into Conformational Change for 14-3-3σ Protein by Molecular Dynamics Simulation

Structural Data on the Periplasmic Aldehyde Oxidoreductase PaoABC from Escherichia coli: SAXS and Preliminary X-ray ...
more infohttps://www.mdpi.com/1422-0067/15/2/2794

The unique features of glycolytic pathways in Archaea | Biochemical JournalThe unique features of glycolytic pathways in Archaea | Biochemical Journal

Abbreviations used: AOR, aldehyde oxidoreductase; ED, Entner-Doudoroff; EM, Embden-Meyerhof; FBA, fructose-1,6-bisphosphate ... glyceraldehyde-3-phosphate ferredoxin oxidoreductase; GLK, glucokinase; KDG, 2-keto-3-deoxygluconate; KDPG, 2-keto-3-deoxy-6- ... aldolase; FBP, fructose-1,6-bisphosphatase; FOR, formaldehyde ferredoxin oxidoreductase; GAP, glyceraldehyde 3-phosphate; GAPDH ...
more infohttp://www.biochemj.org/content/375/2/231

Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead (IPR000674) | InterPro | EMBL-EBIAldehyde oxidase/xanthine dehydrogenase, a/b hammerhead (IPR000674) | InterPro | EMBL-EBI

Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas.. Science 270 1170-6 1995 ... Aldehyde oxidase (EC:1.2.3.1) catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and ... Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead (IPR000674). Short name: Ald_Oxase/Xan_DH_a/b ... The aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain is an evolutionary conserved protein domain [PMID: ...
more infohttp://www.ebi.ac.uk/interpro/entry/IPR000674

Energy Conservation Associated with Ethanol Formation from H2 and CO2 in Clostridium autoethanogenum Involving Electron...Energy Conservation Associated with Ethanol Formation from H2 and CO2 in Clostridium autoethanogenum Involving Electron...

Aldehyde:ferredoxin oxidoreductase are tungsten- or molybdenum iron-sulfur proteins (63-65). It has therefore been considered ... On a reversible molybdenum-containing aldehyde oxidoreductase from Clostridium formicoaceticum. Arch Microbiol 159:244-249. doi ... The formaldehyde:ferredoxin oxidoreductase activity is a side activity of the acetaldehyde:ferredoxin oxidoreductase (63-65), ... Further characterization of 2 different, reversible aldehyde oxidoreductases from Clostridium formicoaceticum, one containing ...
more infohttps://jb.asm.org/content/197/18/2965

d1vlba4d1vlba4

Aldehyde oxidoreductase 1vlb_A2. d1vlba4. A609-A907. Alpha and beta proteins (a+b). Molybdenum cofactor-binding domain. ...
more infohttp://prodata.swmed.edu/malidup/d1vlba4/d1vlba4.html

Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) - WikipediaGlyceraldehyde-3-phosphate dehydrogenase (ferredoxin) - Wikipedia

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an ... Roy R, Menon AL, Adams MW (2001). "Aldehyde oxidoreductases from Pyrococcus furiosus". Methods Enzymol. Methods in Enzymology. ... The systematic name of this enzyme class is D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase. Other names in common use ... Mukund S, Adams MW (1995). "Glyceraldehyde-3-phosphate ferredoxin oxidoreductase, a novel tungsten-containing enzyme with a ...
more infohttps://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(ferredoxin)

ZFIN Publication: Begemann et al., 2001ZFIN Publication: Begemann et al., 2001

Aldehyde Oxidoreductases/genetics*. *Aldehyde Oxidoreductases/metabolism. *Amino Acid Sequence. *Animals. *Cloning, Molecular ...
more infohttps://zfin.org/ZDB-PUB-011002-4

Table of Contents - March 10, 1995, 267 (5203) | ScienceTable of Contents - March 10, 1995, 267 (5203) | Science

Structure of a hyperthermophilic tungstopterin enzyme, aldehyde ferredoxin oxidoreductase. By MK Chan, S Mukund, A Kletzin, MW ...
more infohttp://science.sciencemag.org/content/267/5203

A New Class of Tungsten-Containing Oxidoreductase in Caldicellulosiruptor, a Genus of Plant Biomass-Degrading Thermophilic...A New Class of Tungsten-Containing Oxidoreductase in Caldicellulosiruptor, a Genus of Plant Biomass-Degrading Thermophilic...

... aldehyde ferredoxin oxidoreductase (AOR) (17), and tungsten oxidoreductases of unknown function WOR4 and WOR5. The clade ... Tungsten-dependent aldehyde oxidoreductase: a new family of enzymes containing the pterin cofactor. Metal Ions Biol Syst 39:673 ... Molybdenum incorporation in tungsten aldehyde oxidoreductase enzymes from Pyrococcus furiosus. J Bacteriol 192:4143-4152. doi: ... Structure of a hyperthermophilic tungstopterin enzyme, aldehyde ferredoxin oxidoreductase. Science 267:1463-1469. doi:10.1126/ ...
more infohttps://aem.asm.org/content/81/20/7339

Molybdenum cofactors, enzymes and pathways | NatureMolybdenum cofactors, enzymes and pathways | Nature

... sulphite oxidase and xanthine oxidoreductases. Nature has developed two scaffolds holding molybdenum in place, the iron- ... A periplasmic aldehyde oxidoreductase represents the first molybdopterin cytosine dinucleotide cofactor containing molybdo- ... The Arabidopsis aldehyde oxidase 3 (AAO3) gene product catalyzes the final step in abscisic acid biosynthesis in leaves. Proc. ... Harrison, R. Structure and function of xanthine oxidoreductase: where are we now? Free Radic. Biol. Med. 33, 774-797 (2002). ...
more infohttps://www.nature.com/articles/nature08302?error=cookies_not_supported&code=57f51f3d-fb06-4421-92aa-d426766edcd1

De Novo Biosynthesis of Vanillin in Fission Yeast (Schizosaccharomyces pombe) and Bakers Yeast (Saccharomyces cerevisiae) |...De Novo Biosynthesis of Vanillin in Fission Yeast (Schizosaccharomyces pombe) and Baker's Yeast (Saccharomyces cerevisiae) |...

Reduction of carboxylic acids by Nocardia aldehyde oxidoreductase requires a phosphopantetheinylated enzyme. J. Biol. Chem. 282 ... Purification, characterization, and properties of an aryl aldehyde oxidoreductase from Nocardia sp. strain NRRL 5646. J. ... carboxylic acid reductase: cloning, expression, and characterization of a new aldehyde oxidoreductase family. Appl. Environ. ... Reduction of aryl acids by white-rot fungi for the biocatalytic production of aryl aldehydes and alcohols. Appl. Microbiol. ...
more infohttps://aem.asm.org/content/75/9/2765.full?view=long&pmid=19286778

Protocols and Video Articles Authored by Peter-Leon HagedoornProtocols and Video Articles Authored by Peter-Leon Hagedoorn

The combination of WOR5, formaldehyde oxidoreductase, and aldehyde oxidoreductase forms an efficient catalyst for the oxidation ... aldehyde ferredoxin oxidoreductase, glyceraldehyde-3-phosphate ferredoxin oxidoreductase and the tungsten-containing ... Our finding that the aldehyde oxidation activity of FOR and WOR5 (W-containing oxidoreductase 5) correlates only with the ... WOR5, a Novel Tungsten-containing Aldehyde Oxidoreductase from Pyrococcus Furiosus with a Broad Substrate Specificity Journal ...
more infohttps://www.jove.com/author/Peter-Leon_Hagedoorn

Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms | Drug...Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms | Drug...

2013) A biosensor for aromatic aldehydes comprising the mediator dependent PaoABC-aldehyde oxidoreductase. Electroanalysis 25: ... 2014) Electrical Wiring of the Aldehyde Oxidoreductase PaoABC with a Polymer Containing Osmium Redox Centers: Biosensors for ... aldehyde oxidase. DCPIP. dichlorophenolindophenol. Moco. molybdenum cofactor. RT. room temperature. SNP. single-nucleotide ... Aldehyde oxidase (AO, EC1.2.3.1) is a molybdo-flavoenzyme present in the cytosol of many tissues in mammals (Garattini et al., ...
more infohttp://dmd.aspetjournals.org/content/44/8/1277?ijkey=a708b0f7ac1bad8a4debe6a818e47c220e4ece04&keytype2=tf_ipsecsha

The meninges is a source of retinoic acid for the late-developing hind by Jinhua Zhang, Deborah Smith et al."The meninges is a source of retinoic acid for the late-developing hind" by Jinhua Zhang, Deborah Smith et al.

Aldehyde Oxidoreductases; Animals; Cell Movement; Cells, Cultured; Cerebellum; Cytochrome P-450 Enzyme System; Genes, Reporter ...
more infohttps://escholarship.umassmed.edu/oapubs/1173/
  • During an analysis of the C. bescii genome sequence for oxidoreductase-type enzymes, evidence was uncovered to suggest that the primary redox metabolism of C. bescii has a completely uncharacterized aspect involving tungsten, a rarely used element in biology. (asm.org)