Albumins. Medical search

Water-soluble proteins found in egg whites, blood, lymph, and other tissues and fluids. They coagulate upon heating.

A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.

Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)

Normal human serum albumin mildly iodinated with radioactive iodine (131-I) which has a half-life of 8 days, and emits beta and gamma rays. It is used as a diagnostic aid in blood volume determination. (from Merck Index, 11th ed)

Cell surface proteins that bind albumin with high affinity and trigger intracellular changes influencing the behavior of cells.

A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in cardiovascular and cerebral circulation.

The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).

A major class of water-soluble seed storage proteins. Many proteins from this class are major PLANT ALLERGENS.

Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.

An indicator and reagent. It has been used in serum albumin determinations and as a pH indicator.

A bile pigment that is a degradation product of HEME.

The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.

A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.

Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

The first alpha-globulins to appear in mammalian sera during FETAL DEVELOPMENT and the dominant serum proteins in early embryonic life.

Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.

A process of selective diffusion through a membrane. It is usually used to separate low-molecular-weight solutes which diffuse through the membrane from the colloidal and high-molecular-weight solutes which do not. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Electrophoresis applied to BLOOD PROTEINS.

Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.

The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

The rate dynamics in chemical or physical systems.

An indicator and reagent. It has been used for several purposes including the determination of serum albumin concentrations

Elements of limited time intervals, contributing to particular results or situations.

Chemical analysis based on the phenomenon whereby light, passing through a medium with dispersed particles of a different refractive index from that of the medium, is attenuated in intensity by scattering. In turbidimetry, the intensity of light transmitted through the medium, the unscattered light, is measured. In nephelometry, the intensity of the scattered light is measured, usually, but not necessarily, at right angles to the incident light beam.

Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.

An iron-binding beta1-globulin that is synthesized in the LIVER and secreted into the blood. It plays a central role in the transport of IRON throughout the circulation. A variety of transferrin isoforms exist in humans, including some that are considered markers for specific disease states.

The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.

Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.

All blood proteins except albumin ( = SERUM ALBUMIN, which is not a globulin) and FIBRINOGEN (which is not in the serum). The serum globulins are subdivided into ALPHA-GLOBULINS; BETA-GLOBULINS; and GAMMA-GLOBULINS on the basis of their electrophoretic mobilities. (From Dorland, 28th ed)

The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.

The separation of particles from a suspension by passage through a filter with very fine pores. In ultrafiltration the separation is accomplished by convective transport; in DIALYSIS separation relies instead upon differential diffusion. Ultrafiltration occurs naturally and is a laboratory procedure. Artificial ultrafiltration of the blood is referred to as HEMOFILTRATION or HEMODIAFILTRATION (if combined with HEMODIALYSIS).

A cluster of convoluted capillaries beginning at each nephric tubule in the kidney and held together by connective tissue.

Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.

Two-phase systems in which one is uniformly dispersed in another as particles small enough so they cannot be filtered or will not settle out. The dispersing or continuous phase or medium envelops the particles of the discontinuous phase. All three states of matter can form colloids among each other.

Pathological conditions in the INTESTINES that are characterized by the gastrointestinal loss of serum proteins, including SERUM ALBUMIN; IMMUNOGLOBULINS; and at times LYMPHOCYTES. Severe condition can result in HYPOGAMMAGLOBULINEMIA or LYMPHOPENIA. Protein-losing enteropathies are associated with a number of diseases including INTESTINAL LYMPHANGIECTASIS; WHIPPLE'S DISEASE; and NEOPLASMS of the SMALL INTESTINE.

A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses.

The adhesion of gases, liquids, or dissolved solids onto a surface. It includes adsorptive phenomena of bacteria and viruses onto surfaces as well. ABSORPTION into the substance may follow but not necessarily.

The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.

Starches that have been chemically modified so that a percentage of OH groups are substituted with 2-hydroxyethyl ether groups.

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

State of the body in relation to the consumption and utilization of nutrients.

An amino sugar formed when glucose non-enzymatically reacts with the N-terminal amino group of proteins. The fructose moiety is derived from glucose by the "classical" Amadori rearrangement.

The volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. It is considered to be equivalent to INULIN clearance.

An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in that it binds to a variety of ligands with relatively high affinity and may function in mediating the uptake and lysosomal degradation of macromolecules such as: LIPOPROTEINS; ENDOPEPTIDASES; and PROTEASE INHIBITORS.

The parts of a macromolecule that directly participate in its specific combination with another molecule.

Measurement of the intensity and quality of fluorescence.

The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.

Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.

A group of fatty acids that contain 18 carbon atoms and a double bond at the omega 9 carbon.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.

A condition in which total serum protein level is below the normal range. Hypoproteinemia can be caused by protein malabsorption in the gastrointestinal tract, EDEMA, or PROTEINURIA.

Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.

The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.

Salts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed)

Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)

Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.

Treatment process involving the injection of fluid into an organ or tissue.

Products derived from the nonenzymatic reaction of GLUCOSE and PROTEINS in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of DIABETES MELLITUS.

An examination of chemicals in the blood.

An azo dye used in blood volume and cardiac output measurement by the dye dilution method. It is very soluble, strongly bound to plasma albumin, and disappears very slowly.

Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.

Pathological processes of the KIDNEY or its component tissues.

Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.

The renal tubule portion that extends from the BOWMAN CAPSULE in the KIDNEY CORTEX into the KIDNEY MEDULLA. The proximal tubule consists of a convoluted proximal segment in the cortex, and a distal straight segment descending into the medulla where it forms the U-shaped LOOP OF HENLE.

Stable iodine atoms that have the same atomic number as the element iodine, but differ in atomic weight. I-127 is the only naturally occurring stable iodine isotope.

A technique that combines protein electrophoresis and double immunodiffusion. In this procedure proteins are first separated by gel electrophoresis (usually agarose), then made visible by immunodiffusion of specific antibodies. A distinct elliptical precipitin arc results for each protein detectable by the antisera.

Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).

Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.

Accumulation or retention of free fluid within the peritoneal cavity.

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.

The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.

Serum globulins that migrate to the gamma region (most positively charged) upon ELECTROPHORESIS. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins and conversely most gamma globulins are immunoglobulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

A procedure in which fluid is withdrawn from a body cavity or organ via a trocar and cannula, needle, or other hollow instrument.

Blood proteins that bind to THYROID HORMONES such as THYROXINE and transport them throughout the circulatory system.

A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.

A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.

Globulins of milk obtained from the WHEY.

Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.

Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.

An imbalanced nutritional status resulted from insufficient intake of nutrients to meet normal physiological requirement.

A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance.

An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)

Proteins in the cerebrospinal fluid, normally albumin and globulin present in the ratio of 8 to 1. Increases in protein levels are of diagnostic value in neurological diseases. (Brain and Bannister's Clinical Neurology, 7th ed, p221)

Experimentally induced tumors of the LIVER.

Serum proteins that have the most rapid migration during ELECTROPHORESIS. This subgroup of globulins is divided into faster and slower alpha(1)- and alpha(2)-globulins.

The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.

Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.

A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)

The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.

PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.

Disorders caused by nutritional imbalance, either overnutrition or undernutrition.

Isolation of rat liver albumin messenger RNA. (1/2483)

Rat liver albumin messenger RNA has been purified to apparent homogeneity by means of polysome immunoprecipitation and poly(U)-Sepharose affinity chromatography. Specific polysomes synthesizing albumin were separated from total liver polysomes through a double antibody technique which allowed isolation of a specific immunoprecipitate. The albumin-polysome immunoprecipitate was dissolved in detergent and the polysomal RNA was separated from protein by sucrose gradient centrifugation. Albumin mRNA was then separated from ribosomal RNA by affinity chromatography through the binding of poly(U)-Sepharose to the polyadenylate 3' terminus of the mRNA. Pure albumin mRNA migrated as an 18 S peak on 85% formamide-containing linear sucrose gradients and as a 22 S peak on 2.5% polyacrylamide gels in sodium dodecyl sulfate. It coded for the translation of authentic liver albumin when added to a heterologous protein-synthesizing cell-free system derived from either rabbit reticulocyte lysates or wheat germ extracts. Translation analysis in reticulocyte lysates indicated that albumin polysomes were purified approximately 9-fold from total liver polysomes, and that albumin mRNA was purified approximately 74-fold from albumin polysomal RNA. The total translation product in the mRNA-dependent wheat germ system, upon addition of the pure mRNA, was identified as authentic albumin by means of gel electrophoresis and tryptic peptide chromatography. (+info)

Sentinel lymph node biopsy and axillary dissection in breast cancer: results in a large series. (2/2483)

BACKGROUND: Axillary lymph node dissection is an established component of the surgical treatment of breast cancer, and is an important procedure in cancer staging; however, it is associated with unpleasant side effects. We have investigated a radioactive tracer-guided procedure that facilitates identification, removal, and pathologic examination of the sentinel lymph node (i.e., the lymph node first receiving lymphatic fluid from the area of the breast containing the tumor) to predict the status of the axilla and to assess the safety of foregoing axillary dissection if the sentinel lymph node shows no involvement. METHODS: We injected 5-10 MBq of 99mTc-labeled colloidal particles of human albumin peritumorally in 376 consecutive patients with breast cancer who were enrolled at the European Institute of Oncology during the period from March 1996 through March 1998. The sentinel lymph node in each case was visualized by lymphoscintigraphy, and its general location was marked on the overlying skin. During breast surgery, the sentinel lymph node was identified for removal by monitoring the acoustic signal from a hand-held gamma ray-detecting probe. Total axillary dissection was then carried out. The pathologic status of the sentinel lymph node was compared with that of the whole axilla. RESULTS: The sentinel lymph node was identified in 371 (98.7%) of the 376 patients and accurately predicted the state of the axilla in 359 (95.5%) of the patients, with 12 false-negative findings (6.7%; 95% confidence interval = 3.5%-11.4%) among a total of 180 patients with positive axillary lymph nodes. CONCLUSIONS: Sentinel lymph node biopsy using a gamma ray-detecting probe allows staging of the axilla with high accuracy in patients with primary breast cancer. A randomized trial is necessary to determine whether axillary dissection may be avoided in those patients with an uninvolved sentinel lymph node. (+info)

"The FSGS factor:" enrichment and in vivo effect of activity from focal segmental glomerulosclerosis plasma. (3/2483)

A circulating causative factor has been postulated in focal segmental glomerulosclerosis (FSGS). It has been shown that serum or plasma from some FSGS increases glomerular albumin permeability (Palb) in vitro. Palb greater than 0.5 (i.e., FS activity) is associated with recurrence after transplantation. Specimens from 15 FSGS patients were studied to document the presence of a permeability factor, to isolate this factor, to characterize its biochemical properties, and to show its effect in vivo. Total lipids were extracted by chloroform/methanol (2: 1); FS activity was absent from total lipid extract. Chylomicrons and lipoproteins were removed from the plasma with dextran sulfate, followed by sequential precipitation of proteins at 50 and 70% ammonium sulfate saturation. FS activity was retained in the 70% ammonium sulfate supernatant and exhibited a 100-fold purification. FS activity was lost after heating at 100 degrees C for 10 min or after protease digestion. Under nondenaturing conditions, electrophoresis of the FSGS 70% supernatant showed a prominent low molecular weight band that was not evident in the 70% supernatant from normal plasma. Dialysis and centrifugation-based membrane ultrafiltration of the FSGS factor indicated a molecular size between 30 and 50 kD. Injection of the 70% FSGS supernatant into rats caused a threefold increase in urine protein in collections from 6 to 24 h after injection. No increase in proteinuria occurred in rats injected with 70% supernatant from normal individuals. It is concluded that the FSGS factor is a low molecular weight protein with the potential to increase Palb in vitro and to cause proteinuria in vivo. (+info)

Triacylglycerol biosynthesis in rat adipose-tissue homogenates. (4/2483)

The optimum cofactor requirements for triacylglycerol biosynthesis in rat adipose-tissue homogenates containing mitochondrial, microsomal and cytosolic fractions were investigated. In general the optimum concentrations of cofactors for triacylglycerol biosynthesis were found to differ from those for total fatty acid esterification. The results provided further evidence for the key role of phosphatidate phosphohydrolase in the regulation of triacylglycerol biosynthesis. Albumin was included in the incubation medium to permit the use of concentrations of added fatty acids that would swamp the effects of endogenous fatty acids. The addition of albumin had little effect on the incorporation of palmitic acid and stearic acid into lipids including triacylglycerols. By contrast, a critical concentration of albumin (about 60 muM) was required before incorporation of oleic acid or linoleic acid into triacylglycerols occurred. The system was used to study the incorporation of different 1-14C-labelled fatty acids from a mixture of unesterified fatty acids [palmitic acid 30%; stearic acid 10%; oleic acid 40%; linoleic acid 20% (molar percentages)] separately into the positions 1,2 and 3 of triacyl-sn-glycerols. In general the stereo-specific distribution of the labelled fatty acids incorporated into triacylglycerols paralleled the normal distribution of fatty acids within rat adipose-tissue triacylglycerols, suggesting that the specificities of the relevant acyltrasferases have the major role in determining the positional distribution of fatty acids within triacylglycerols. (+info)

von Willebrand factor contained in a high purity FVIII concentrate (Fanhdi) binds to platelet glycoproteins and supports platelet adhesion to subendothelium under flow conditions. (5/2483)

BACKGROUND AND OBJECTIVE: There is evidence suggesting that von Willebrand factor (VWF) from high purity factor VIII concentrates could be of clinical use in the management of patients suffering from VWD. We analyzed structural and functional characteristics of VWF present in a high purity factor VIII concentrate VWFHPC (Fanhdi). The multimeric structure, the ability to bind to platelet GP Ib/IX or GP IIb/IIIa, and the capacity of VWFHPC to promote platelet adhesion on injured vessels were investigated and compared with that present in standard plasma cryoprecipitates [VWFCRYO]. DESIGN AND METHODS: Binding studies were carried out by incubating radiolabeled VWF and washed platelets, which were activated with either ristocetin (1 mg/mL; for GP Ib/IX), or thrombin (2.5 U/mL; for GP IIb/IIIa). Platelet adhesion was assessed in a perfusion system (shear rate = 800 s-1, 10 min) in which the source of VWF was added (at 0.4 or 0.8 U/mL VWF:Ag) to washed platelets and red cells suspended in a human albumin solution. The deposition of platelets onto the perfused subendothelial surface was morphometrically evaluated and expressed as percentage of surface coverage (%SC). RESULTS: The VWFHPC (152 Units VWF:RCof/mg protein; VWF:RCof/VWF:Ag = 0.97), lacked only a small proportion of high-molecular-weight multimers present in VWFCRYO. Binding affinities (Kd values, nM) of VWFHPC were similar to those of VWFCRYO (5.3 +/- 0.86 vs 5.2 +/- 0.95, for GP Ib/IX; and 11.6 +/- 2.7 vs 15.4 +/- 1.7 for GPIIb-IIIa). A slightly, though not significantly, higher binding capacity for these receptors (Bmax values, molecules/pit) was obtained for VWFHPC. The %SC in perfusions in the presence of albumin was < 10%. Addition of VWFHPC or VWFCRYO significantly increased the %SC, with values of 27.1 +/- 4.9 and 17.5 +/- 2.8%, respectively with 0.4 U/mL (p < 0.004 and p < 0.02 vs albumin); and 30.8 +/- 4.9% and 20.03 +/- 4.1%, respectively, at 0.8 U/mL (p < 0.001 and p < 0.02 vs albumin). INTERPRETATION AND CONCLUSIONS: Our data show that VWF present in the high purity FVIII concentrate Fanhdi retains the functional capacity to bind to GPs Ib/IX and IIb/IIIa and to promote platelet adhesion onto exposed subendothelium. (+info)

Secretory cells of the peripheral pulmonary epithelium as targets for toxic agents. (6/2483)

The extracellular lining of the pulmonary peripheral airways is of vital importance to the lung. In this report, some aspects of the pulmonary extracellular lining and the epithelial cells believed to be responsible for its formation and secretion have been briefly reviewed. The influence of a number of toxic agents on the extracellular lining either directly or via those cells involved in its formation indicates that the extracellular lining may be important in understanding numerous toxic agent interactions with the lung. (+info)

Peritoneal clearance of leptin in CAPD patients: impact of local insulin administration. (7/2483)

INTRODUCTION: The ob gene product leptin is secreted by fat cells and the serum leptin levels reflects the body fat content. Markedly elevated serum leptin levels have been reported in patients with chronic renal failure. The aim of the present study was to assess if the dialysate leptin levels in peritoneal dialysate are similar to what can be expected from passive diffusion or if intraperitoneal synthesis of leptin may occur. METHODS: We studied 39 patients (20 males), mean age 54+/-12 years, who had been treated with peritoneal dialysis for 17+/-12 months. Ten of the patients were diabetics of which seven used intraperitoneal insulin. A 24-h collection of dialysate was performed and dialysate and fasting blood samples were analysed for leptin, albumin and beta2-microglobulin, and the peritoneal clearances (PCl) were calculated for these solutes. RESULTS: Serum leptin (mean 47+/-76, range 3-350 ng/ml) was related to body mass index (r=0.35, P<0.05). In multiple regression analysis, serum leptin also correlated to serum TNF-alpha. Although dialysate leptin levels correlated to serum leptin, they were higher than expected from the molecular weight of 16 kD. PCl of leptin was 1.3 ml/min (range 0.2-5.9 ml/min), which was 1.6 times higher than expected from the molecular weight of leptin and PCl for albumin and beta2-microglobulin, not taking the protein binding of leptin into account. A strong correlation was found between PCI for albumin and beta2-microglobulin (r = 0.68, P < 0.0001) but neither PCl albumin, nor PCl beta2-microglobulin correlated to PCI leptin. The PCl of leptin was markedly higher in diabetics using intraperitoneal insulin (n = 7) compared to the other 32 patients (2.6+/-2.0 vs 1.1+/-0.7 ml/min, P<0.05). CONCLUSION: Serum leptin is locally produced in the peritoneal cavity, and intraperitoneal insulin enhances local production of leptin. (+info)

The cytotoxicity of mafosfamide on G-CSF mobilized hematopoietic progenitors is reduced by SH groups of albumin--implications for further purging strategies. (8/2483)

The efficacy of mafosfamide purging depends on factors like incubation time, drug and erythrocyte concentration. To determine the influence of protein-bound SH groups in the incubation medium, the cytotoxicity of mafosfamide on G-CSF mobilized CD34+/- cells was evaluated by short-term culture assays and drug concentration measurements. 100 micromol/ml mafosfamide was incubated for 30 min in five buffers (PBS, PBS with 1%, 5% and 10% BSA and plasma). The mean calculated areas under the concentration-time curves (AUC) were 2489 +/- 198, 1561 +/- 286, 976 +/- 201, 585 +/- 62 and 605 +/- 196 micromol/l/min. The mean reductions of CFU-GM growth were 79.4%, 73.0%, 62.5%, 30.3%, 6.2% respectively. Similar results were obtained for BFU-E. Regression analysis showed a good correlation between cytotoxicity and AUCs (CFU-GM: r = 0.8195; BFU-E: r = 0.8207). This effect is well explained by the different concentrations of SH moieties in the incubation medium resulting in a higher drug binding capacity. The profound difference between AUCs and CFU-GMs in plasma and 10% BSA cannot be explained by the quantity of SH-groups. It is probably due to an additional enzymatic drug degeneration by the 3'-5'exonuclease subsite of plasma DNA polymerase. In conclusion, the concentration of albumin-associated SH groups strongly influences the cytotoxicity of mafosfamide. It has to be considered as a new and important aspect in ex vivo bone marrow purging. (+info)

Serum albumin purification[edit]. Of many uses of affinity chromatography, one use of it is seen in affinity purification of ... In affinity purification of serum albumin, the stationary used for collecting or attracting serum proteins can be Cibacron Blue ... This type of purification is helpful in removing excess albumin and α2-macroglobulin contamination, when performing mass ... Naval, Javier; Calvo, Miguel; Lampreave, Fermin; Piñeiro, Andrés (1983-01-01). "Affinity chromatography of serum albumin: An ...

https://en.wikipedia.org/wiki/Immunoaffinity_chromatography

Albumin[edit]. Albumin is the major fraction in a normal SPEP. A fall of 30% is necessary before the decrease shows on ... Absence of albumin, known as analbuminaemia, is rare. A decreased level of albumin, however, is common in many diseases, ... Increased AMG is also noted in rats with no albumin indicating that this is a response to low albumin rather than nephrotic ... Albumin - alpha-1 interzone[edit]. Even staining in this zone is due to alpha-1 lipoprotein (high density lipoprotein - HDL). ...

https://en.wikipedia.org/wiki/Serum_proteins

Albumin historia[muokkaa , muokkaa wikitekstiä]. Nauhoittaminen ja julkaisu[muokkaa , muokkaa wikitekstiä]. Rumpali Steven ... Vaihtoehtoisesti hän esitti kahden tupla-albumin - tässä tapauksessa siis Use Your Illusion I:n ja Use Your Illusion II:n - ... Albumin on tuottanut Mike Clink, ja se julkaistiin 17. syyskuuta vuonna 1991 samanaikaisesti yhtyeen neljännen studioalbumin, ... Albumin avausraita "Right Next Door to Hell" kertoo Rosen mukaan hänen jatkuvasta vihasuhteestaan pakkomielteiseen naapuriinsa. ...

https://fi.wikipedia.org/wiki/Use_Your_Illusion_I

Albumin single[muokkaa , muokkaa wikitekstiä]. Vuosi Kappale Billboard Hot 100 Hot R&B/Hip-Hop Singles & Tracks ... Albumin kaikki kappaleet ovat ennen julkaisemattomia. Still I Risen julkaisi 14. joulukuuta 1999 Interscope Records, Death Row ... ". "Baby Don't Cry (Keep Ya Head Up II)" on myös albumin ainoa kappale, josta kuvattiin musiikkivideo. ...

https://fi.wikipedia.org/wiki/Still_I_Rise

Albumin tuotti Martin Birch, ja levy-yhtiö EMI julkaisi albumin Euroopassa 11. huhtikuuta 1988. Yhdysvalloissa albumin julkaisi ... Albumin kahdeksasta kappaleesta kolmea säveltänyt Adrian Smith erosi yhtyeestä albumin kiertueen jälkeen. ... Albumin teema, sanoitukset ja synty[muokkaa , muokkaa wikitekstiä]. »Se oli meidän seitsemäs studiolevy, eikä mulla ollut sille ... Albumin kappaleista "Can I Play with Madness" (Britannian singlelistan 3.), "The Evil That Men Do" (brittilistan 5.) ja "The ...

https://fi.wikipedia.org/wiki/Seventh_Son_of_a_Seventh_Son

Albumin konsepti[muokkaa , muokkaa wikitekstiä]. Albumin peruskonsepti on erittäin tummanpuhuva. Sanoitukset käsittelevät ... Albumin myötä yhtye nousi suureen suosioon ja siitä tuli yksi grunge-musiikin johtavista kokoonpanoista. Albumi käsittelee ... Monet albumin sanoituksista, eritoten kappaleet "God Smack", "Angry Chair" ja "Junkhead", puivat laulaja Layne Staleyn ... Albumin viimeinen kappale "Would?" on Cantrellin kunnianosoitus vuonna 1990 kuolleelle Andrew Woodille. ...

https://fi.wikipedia.org/wiki/Dirt

Kyseisessä julkaisussa albumin nimi on kuitenkin Alive IV: The Millenium Concert. Kappalelista[edit , edit source]. Levy 1[edit ... sillä albumin julkaisusta tiedotettiin jo vuonna 1999[2]. Albumin kansitaide ehdittiin jo paljastaa, ja levylle konsertissa ... Albumin taustaa[edit , edit source]. Kissin alkuperäisen eli Gene Simmonsin, Paul Stanleyn, Peter Crissin ja Ace Frehleyn ... Albumin tuotti Mark Opitz[1], ja se on yhtyeen Alive-livealbumisarjan neljäs osa. ...

https://fi.wikipedia.org/wiki/Kiss_Symphony:_Alive_IV

tammikuuta 2012.[14] Albumin nimi, MDNA on näennäinen lyhenne Madonnan nimestä.[15][16] Albumin nimestä nousi pian nimen ... Kansikuva ja albumin nimeäminen[muokkaa , muokkaa wikitekstiä]. Madonna julkisti uuden albuminsa nimen The Graham Norton ... Albumin avaussingle Give Me All Your Luvin' vuosi internetiin 8. marraskuuta nimellä "Give Me All Your Love".[5] 15. joulukuuta ... Albumin ensimmäinen single, "Give Me All Your Luvin'", julkaistiin helmikuun 3. päivä digitaalisesti.[3] Singlen demo vuosi ...

https://fi.wikipedia.org/wiki/MDNA

... albumin, transferrin and transthyretin: a practical, simple and clinically relevant approach in a large cohort". Journal of ... "Transcriptional regulation of transferrin and albumin genes by retinoic acid in human hepatoma cell line Hep3B". The ...

https://en.wikipedia.org/wiki/Transferrin

Serum albumin. *Human serum albumin. *Bovine serum albumin. *Prealbumin. Other. *C-reactive protein ...

https://en.wikipedia.org/wiki/Antibody

... is known to be plasma protein bound to albumin, SHBG, and CBG.[4][5][6] ...

https://en.wikipedia.org/wiki/Danazol

... , also known as "whey protein", is the albumin contained in milk and obtained from whey. Lactalbumin is found in the ... Serum proteins, including albumin, remained unchanged and within normal range, indicating that protein replenishment per se was ... The presence in the serum albumin fraction of glutamylcysteine groups (rare in food protein) and the specific intramolecular ... Whey protein concentrate was prepared so that the most thermosensitive proteins, such as serum albumin which contains 6 ...

https://en.wikipedia.org/wiki/Lactalbumin

albumin. *α1-acid glycoprotein. *lipoproteins. Some drug interactions with warfarin are due to changes in protein binding.[16] ...

https://en.wikipedia.org/wiki/Adverse_drug_reaction

In medicine, it is known as the primary carrier of basic (positively charged) drugs (whereas albumin carries acidic (negatively ... Aging causes a small decrease in plasma albumin levels; if anything, there is a small increase in alpha-1-acid glycoprotein. ... the other three are albumin, very low-density lipoprotein particle size, and citrate).[7] ...

https://en.wikipedia.org/wiki/Orosomucoid

Albumin- oids Crude Fiber Extractive Matter Free From Nitrogen Fat Meadow hay- poor 14.3 5.0 7.5 33.5 38.2 1.5 ...

https://en.wikipedia.org/wiki/Haystack

Albumin , 4.0 g/dl. *White blood count ≥ 15,000/µl. Other studies have reported the following to be the most important adverse ...

https://en.wikipedia.org/wiki/Hodgkins_lymphoma

... is highly plasma protein bound, 99% bound to albumin. Albumin is the most abundant protein found in human plasma ... "plasma albumin". TheFreeDictionary.com. Saunders. Retrieved 7 January 2018. de Vries HE, Kuiper J, de Boer AG, Van Berkel TJ, ...

https://en.wikipedia.org/wiki/Zafirlukast

Rhian Daly (August 15, 2014). "Celebration - 'Albumin'". Nme.com. Retrieved April 29, 2018. T. Ballard Lesemann (October 24, ... Albumin - (August, 2014) Wounded Healer - (June, 2017) "Diamonds" - (December 5, 2005) "War" - (February 20, 2006) "New Skin ...

https://en.wikipedia.org/wiki/Celebration_(2000s_band)

For example, this technique is used to investigate how fatty acids bind to serum albumin (a highly abundant blood protein), ... Berde CB, Hudson BS, Simoni RD, Sklar LA (January 1979). "Human serum albumin. Spectroscopic studies of binding and proximity ... which will compete for binding sites on serum albumin. α-Parinaric acid has been used to study the hydrophobicity and foaming ... binding to bovine serum albumin". Biochemistry. 16 (23): 5100-8. doi:10.1021/bi00642a024. PMID 911814. ...

https://en.wikipedia.org/wiki/Alpha-Parinaric_acid

Poznansky, M. J. (1984). "Enzyme-albumin polymers. New approaches to the use of enzymes in medicine". Applied Biochemistry and ...

https://en.wikipedia.org/wiki/Enzyme_replacement_therapy

album-in 1922. Molecular studies have shown that the current species concept for H. repandum needed revision as there was a ...

https://en.wikipedia.org/wiki/Hydnum_repandum

... , or trenbolone cyclohexylmethylcarbonate, sold under the brand names Parabolan and Hexabolan, is a synthetic, injected anabolic-androgenic steroid (AAS) of the nandrolone group and an androgen ester - specifically, the C17β hexahydrobenzylcarbonate (cyclohexylmethylcarbonate) ester of trenbolone - which was marketed in France for medical use in humans but has since been discontinued.[1] It was introduced in France in 1980 and was voluntarily discontinued by its manufacturer in 1997.[1][2] The drug acts as a long-lasting prodrug of trenbolone when administered via intramuscular injection.[1] It was used clinically at a dosage of one ampoule (76 mg, corresponding to 50 mg trenbolone base) every 10 days.[1] ...

https://en.wikipedia.org/wiki/Trenbolone_hexahydrobenzylcarbonate

Androstenedione immunogens: Androvax (androstenedione albumin). *Ovandrotone albumin (Fecundin). *#WHO-EM. *‡Withdrawn from ...

https://en.wikipedia.org/wiki/Androgen

InChI=1S/C29H31NO4/c1-20-26-14-11-24(32)19-27(26)34-29(28(20)21-5-9-23(31)10-6-21)22-7-12-25(13-8-22)33-18-17-30-15-3-2-4-16-30/h5-14,19,29,31-32H,2-4,15-18H2,1H3/t29-/m0/ ...

https://en.wikipedia.org/wiki/Acolbifene

The Women's Health Initiative trials were conducted between 1991 and 2006 and were the first large, double-blind, placebo-controlled clinical trials of HRT in healthy women.[52] Their results were both positive and negative, suggesting that during the time of hormone therapy itself, there are increases in invasive breast cancer, stroke and lung clots. Other risks include increased endometrial cancer, gallbladder disease, and urinary incontinence, while benefits include decreased hip fractures, decreased incidence of diabetes, and improvement of vasomotor symptoms. There also is an increased risk of dementia with HRT in women over 65, though when given earlier it appears to be neuroprotective. After the cessation of HRT, the WHI continued observe its participants, and found that most of these risks and benefits dissipated, though some elevation in breast cancer risk did persist.[24] Other studies have also suggested an increased risk of ovarian cancer.[43] The arm of the WHI receiving combined ...

https://en.wikipedia.org/wiki/Hormone_replacement_therapy

The plasma protein binding of norethisterone is 97%.[4] It is bound 61% bound to albumin and 36% bound to SHBG.[4] ...

https://en.wikipedia.org/wiki/Norethindrone

CDMT was the key steroid administered to approximately 10,000 athletes from East Germany (GDR) as secret official policy, often without their knowing the nature of the "vitamins" they were forced to take. The doping program was run by the East German Government from about 1968 until 1989 when the Berlin Wall was destroyed. The doping program was known as State Plan Topic 14.25. The doping was done in secret; it was only in the 1990s that Franke and Berendonk looked closely at the original archived information and discovered the true scope of just how well-planned and successful the doping regime had been (in terms of medal success and world record performances).[2] After the collapse of the East German regime, people responsible for the forced doping were found guilty of causing grievous bodily harm to about 10,000 sportspeople; victims were compensated. In later life former athletes developed serious health problems believed due to the drugs; psychotic episodes were attributed to CDMT.[3] ...

https://en.wikipedia.org/wiki/Chlorodehydromethyltestosterone

... (INN) (brand names Colpotrofin, Colpotrophine, Delipoderm), also known as estradiol 3-propyl 17β-methyl diether, is a synthetic steroidal estrogen which is used topically in a 1% cream formulation.[1][2][3][4] It is the 3-propyl and 17β-methyl diether of estradiol.[5] The drug is described as a tropic agent and antiseborrheic.[1] It has not been found to be effective in the treatment of androgenic alopecia or other conditions of cutaneous androgenization.[6][7] ...

https://en.wikipedia.org/wiki/Promestriene

... (INN, JAN) (brand names Steranabol Depo, Steranabol Ritardo; former developmental code name FI-5852), or oxabolone cypionate, also known as 4-hydroxy-19-nortestosterone 17β-cypionate or estr-4-en-4,17β-diol-3-one 17β-cypionate, is synthetic and injected anabolic-androgenic steroid (AAS) and derivative of nandrolone (19-nortestosterone) which has been marketed in Europe.[1][2][3] It is the C17β cypionate ester and a prodrug of oxabolone (4-hydroxy-19-nortestosterone).[2][3] ...

https://en.wikipedia.org/wiki/Oxabolone_cipionate

A 2017 population-based, matched-cohort study of 93,197 men aged 66 years and older with BPH found that finasteride and dutasteride were associated with a significantly increased risk of depression (HR, 1.94; 95% CI, 1.73-2.16) and self-harm (HR, 1.88; 95% CI, 1.34-2.64) during the first 18 months of treatment, but were not associated with an increased risk of suicide (HR, 0.88; 95% CI, 0.53-1.45).[31][32][33][21] After the initial 18 months of therapy, the risk of self-harm was no longer heightened, whereas the elevation in risk of depression lessened but remained marginally increased (HR, 1.22; 95% CI, 1.08-1.37).[31][32][21] The absolute increase in the rate of depression was 247 per 100,000 patient-years and of self-harm was 17 per 100,000 patient-years.[21][34] As such, on the basis of these findings, it has been stated that cases of depression in patients that are attributable to 5-ARIs will be encountered on occasion, while cases of self-harm attributable to 5-ARIs will be encountered ...

https://en.wikipedia.org/wiki/5α-Reductase_inhibitor

Serum albumin[edit]. Main article: Serum albumin. Serum albumin is the most abundant blood plasma protein and is produced in ... For the specific albumins found in vertebrate bloodstreams, see serum albumin. For other uses, see Albumin (disambiguation). ... Serum albumin levels[edit]. The normal range of human serum albumin in adults (, 3 y.o.) is 3.5 to 5 g/dL. For children less ... Wikisource has the text of the 1911 Encyclopædia Britannica article Albumin.. *Albumins at the US National Library of Medicine ...

https://en.wikipedia.org/wiki/Albumin

ALBUMIN_1 (PS00212). Accession PS00212 Integration. Serum albumin, conserved site (IPR020857) Member database. PROSITE patterns ...

http://www.ebi.ac.uk/interpro/ISignatureOverview?sig=PS00212&query=P

Albumin definition, any of a class of simple, sulfur-containing, water-soluble proteins that coagulate when heated, occurring ... albumin. in Science. albumin. [ăl-byōō′mĭn]. *A class of proteins found in egg white, milk, blood, and various other plant and ... albumin. in Medicine. albumin. (ăl-byōō′mĭn). n.. *A class of simple, water-soluble proteins that can be coagulated by heat and ... albumin. albumen. noun. *any of a group of simple water-soluble proteins that are coagulated by heat and are found in blood ...

https://www.dictionary.com/browse/albumin

InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.

http://www.ebi.ac.uk/interpro/protein/P02768

I had a test done showing my albumin levels are a little low than normal. Can this be dangerous?? If so in what ... ... Albumin gopo92 Hello. I am 18 years ood and have been suffering from intestinal disease since 10 years. I had a test done ... Albumin is a protein produced by the liver and it forms an important part of the blood as it helps keep the water in the blood ... If your albumin were very low you then you would be increasingly worried that this value was representative of one of the ...

https://www.medhelp.org/posts/Undiagnosed-Symptoms/Albumin/show/1495525

Is there a home test for albumin levels?. Not for blood albumin; you can test for high albumin levels in urine with a dipstick ... Albumin may also be ordered to evaluate a persons nutritional status.. When is it ordered?. An albumin test is frequently ... The urine albumin test (in the past, called a microalbumin test) detects and measures albumin in the urine as an early ... A low albumin level may be an indication that further investigation may be warranted. A low albumin may reflect a temporary ...

https://www.labcorp.com/help/patient-test-info/albumin

... with albumin) Injection: learn about side effects, dosage, special precautions, and more on MedlinePlus ... with albumin) injection. If you are female, you should use birth control during your treatment with paclitaxel (with albumin) ... Paclitaxel (with albumin) may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: *pain ... Paclitaxel (with albumin) injection may cause a large decrease in the number of white blood cells (a type of blood cell that is ...

https://medlineplus.gov/druginfo/meds/a619008.html

The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery ... Interdomain zinc site on human albumin. Alan J. Stewart, Claudia A. Blindauer, Stephen Berezenko, Darrell Sleep, Peter J. ... Interdomain zinc site on human albumin. Alan J. Stewart, Claudia A. Blindauer, Stephen Berezenko, Darrell Sleep, Peter J. ... Interdomain zinc site on human albumin. Alan J. Stewart, Claudia A. Blindauer, Stephen Berezenko, Darrell Sleep, and Peter J. ...

https://www.pnas.org/content/100/7/3701/tab-article-info

A list of US medications equivalent to Human Albumin Demo is available on the Drugs.com website. ... Human Albumin Demo is a medicine available in a number of countries worldwide. ... Ingredient matches for Human Albumin Demo. Albumin Human. Albumin Human is reported as an ingredient of Human Albumin Demo in ... Human Albumin Demo. Human Albumin Demo may be available in the countries listed below. ...

https://www.drugs.com/international/human-albumin-demo.html

Albumin: The Natural Choice for Diagnostic Tests The availability of established diagnostic kits has enabled researchers to ... The patent involves the formulation and use of recombinant human serum albumin and gluteraldehyde, and now becomes part of ... CryoLife purchases patent involving formulation, use of recombinant human serum albumin and gluteraldehyde CryoLife, Inc., an ... high quality Bovine Serum Albumin, to do contract filling & provide BSA to customers requiring less than Proliants standard 10 ...

https://www.news-medical.net/?tag=/Bovine-Serum-Albumin

ALBUMIN PHENOTYPES IN TURKEYS. Indalecio R. Quinteros, R. W. C. Stevens, C. Stormont and V. S. Asmundson ... ALBUMIN PHENOTYPES IN TURKEYS. Indalecio R. Quinteros, R. W. C. Stevens, C. Stormont and V. S. Asmundson ... ALBUMIN PHENOTYPES IN TURKEYS. Indalecio R. Quinteros, R. W. C. Stevens, C. Stormont and V. S. Asmundson ...

http://www.genetics.org/content/50/4/579

Serum albumin, often referred to simply as blood albumin, is an albumin (a type of globular protein) found in vertebrate blood ... Serum albumin is widely distributed in mammals. The human version is human serum albumin. Bovine serum albumin, or BSA, is ... Nephrotic syndrome patients are sometimes given albumin to replace the lost albumin. The general structure of albumin is ... Human serum albumin is encoded by the ALB gene. Other mammalian forms, such as bovine serum albumin, are chemically similar. ...

https://en.wikipedia.org/wiki/Serum_albumin

Albumin Antibody in Routine Rhesus Grouping Br Med J 1951; 1 :1490 ... Albumin Antibody in Routine Rhesus Grouping. Br Med J 1951; 1 doi: https://doi.org/10.1136/bmj.1.4721.1490 (Published 30 June ...

http://www.bmj.com/content/1/4721/1490

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View more information on albumin>human serum albumin. ... Sigma-Aldrich has partnered with the technology holders of recombinant human albumin products expressed in Rice, Pichia Product Directory > Biochemicals and Reagents > Proteins and Derivatives > Albumin > Recombinant/Transgenic Human ... Albumin human recombinant, expressed in Pichia pastoris, 5% in aqueous buffer, ≥90% (SDS-PAGE) * pricing ...

https://www.sigmaaldrich.com/life-science/biochemicals/biochemical-products.html?TablePage=105233201

This medicine works by increasing plasma volume or levels of albumin in the blood. Albumin is used to replace blood volume loss ... Medicinal albumin is made of plasma proteins from human blood. ... Albumin is a protein produced by the liver that circulates in ... What is albumin?. Albumin is a protein produced by the liver that circulates in plasma (the clear liquid portion of your blood ... How is albumin given?. Albumin is injected into a vein through an IV. A healthcare provider will give you this injection. ...

https://www.rexhealth.com/rh/health-library/document-viewer/?id=d02376a1

Preoperative albumin to globulin ratio predicts survival in clear cell renal cell carcinoma patients. In this retrospective ... The role of preoperative albumin to globulin ratio in predicting prognosis in testicular cancer patients. In recent years, the ... Prognostic role of pretreatment serum albumin in renal cell carcinoma: a systematic review and meta-analysis. Recently, many ... Thus, we examined the association of C-reactive protein (CRP), haptoglobin, albumin and white blood cells (WBC) with prostate ...

https://www.urotoday.com/tags/albumin.html

Make research projects and school reports about albumin easy with credible articles from our FREE, online encyclopedia and ... Principal forms are egg albumin (egg white), milk albumin and blood albumin. In a healthy human, it constitutes about 5% of the ... albumin (ălbyōō´mən) [Lat.,=white of egg], member of a class of water-soluble, heat-coagulating proteins. Albumins are widely ... Albumins occur in egg white (the protein component of which is known as albumen), blood, milk, and plants. Serum albumins, ...

https://www.encyclopedia.com/science-and-technology/biochemistry/biochemistry/albumin

Rate your experience with Albumin-Saline injection on - WebMD including the side effects, drug interactions, effectiveness, ...

https://www.webmd.com/drugs/drugreviewpost-90606-Albumin-Saline+injection.aspx?post=new&

Human serum albumin (HSA) is the intravenous protein most commonly used in the world for therapeutic ends. It is employed to ... Human serum albumin (HSA) is the intravenous protein most commonly used in the world for therapeutic ends. It is employed to ... Commercial albumin is currently extracted from blood, but the lack of sufficient reserves to cover all worldwide needs has ... While the price at the pharmacy of albumin produced using plasma is 4 euros per gram, that obtained from yeasts or mammal cells ...

https://scienceblog.com/10280/human-albumin-from-tobacco-plants/

Treatments and Tools for albumin. Find albumin information, treatments for albumin and albumin symptoms. ... albumin - MedHelps albumin Center for Information, Symptoms, Resources, ... Hi, My most recent tests came back with high lymphocytes (4.46X10) and high albumin (28.8 ... ... My 15 year olds results: albumin 4.71 globulin 2.23 a/g ratio 2.11 bilirubin total... ...

http://www.medhelp.org/tags/show/501/albumin

Using the results of quantitative CSF and serum albumin assays, a CSF (in mg/dL)/serum (in g/dL) albumin index can be ... Albumin is a particularly suitable indicator of protein because it is neither synthesized nor metabolized intrathecally. In CSF ... The degree of permeability of the blood-brain barrier can be evaluated by the quantitative measurements of albumin in the CSF ... Albumin, Cerebrospinal Fluid. 1746-7. 012230. Albumin, CSF. mg/dL. 1746-7. ...

https://www.labcorp.com/test-menu/18916/albumin-cerebrospinal-fluid

Albumin is the most prevalent protein in your blood, and without it, you can experience a number of symptoms. ... The role of albumin in fluid balance and transport means low albumin levels can cause bodily problems that manifest in symptoms ... The albumin in your blood moves the mineral calcium, the hormone progesterone and medicines throughout your tissues. Albumin ... To maintain normal blood albumin ranges, you should have between 3.4 and 5.4 g/dL of albumin in your blood. ...

https://www.livestrong.com/article/488109-role-of-albumin/

ALBUMIN HUMAN (UNII: ZIF514RVZR) (ALBUMIN HUMAN - UNII:ZIF514RVZR) ALBUMIN HUMAN. 12.5 g in 50 mL. ... Albumin (Human) 25% Solution AlbuRx® 25 Contains: 12.5 g Albumin (Human) in 50 mL of buffered diluent. Stabilized with 0.02 M ... One vial containing 12.5 grams of albumin. [NDC 44206-251-90]. 100 mL. 44206-251-10. One vial containing 25 grams of albumin. [ ... In all these settings, the circulating albumin mass is initially maintained by a gradual transfer of extravascular albumin to ...

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ad74b7f5-b380-47ab-b19d-eef92c8eb7a4

Biochemically, the mutant was characterized by an extraordinarily low serum albumin content and a hyperlipidemia. Total serum ... Serum cholesterol was inversely correlated with a decrease in albumin; the correlation coefficient for ablumin was --.92. These ... rats may serve as a model of human familial analbuminemia and may also be useful in elucidating the functional roles of albumin ...

http://science.sciencemag.org/content/205/4406/590

Learn about the known and possible side effects of Albumin Human Not everyone will experience one or all of these side effects ... Albumin Human - Information. Albumin Human is derived from human plasma, used to treat shock as a result of blood loss in the ... Side effect(s) of Albumin Human Read the side effects of Albumin Human as described in the medical literature. In case of any ... Albumin 20% (100ml) , Biseko , Biseko (50ml) , Granocyte , Roferon -A , Sll Human Albumin , Verglob 1000MG , Verglob 2500 , ...

http://www.medindia.net/drugs/medication-side-effects/albumin_human.htm

NANOPARTICLE ALBUMIN-BOUND PACLITAXEL (Na no PAHR ti kuhl al BYOO muhn-bound PAK li TAX el) is a chemotherapy drug. ... Nanoparticle Albumin-Bound Paclitaxel injection. What is this medicine?. NANOPARTICLE ALBUMIN-BOUND PACLITAXEL (Na no PAHR ti ... an unusual or allergic reaction to paclitaxel, albumin, other chemotherapy, other medicines, foods, dyes, or preservatives ...

https://www.nationwidechildrens.org/family-resources-education/family-resources-library/nanoparticle-albumin-bound-paclitaxel-injection

Albumin from hamster for your research needs. Find product specific information including CAS, MSDS, protocols and references. ...

https://www.sigmaaldrich.com/catalog/product/sial/a5409?lang=en®ion=US

Albumin Human (UNII: ZIF514RVZR) (Albumin Human - UNII:ZIF514RVZR) Albumin Human. 2.5 g in 50 mL. ... Albumin (Human). 5%, USP. albuked™ 5 Heated 60°C 10 hours. For Intravenous Infusion Only. This package contains: 12.5 g albumin ... Situations in Which Albumin Administration is Not Warranted(1) In chronic nephrosis, infused albumin is promptly excreted by ... it is common practice to adjust the albumin and crystalloid pump prime to achieve a hematocrit of 20% and a plasma albumin ...

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fac1e3bd-5b30-f251-c5ae-2226caecf51d&audience=consumer

Albumin human synonyms, Albumin human pronunciation, Albumin human translation, English dictionary definition of Albumin human ... albumin. (redirected from Albumin human). Also found in: Thesaurus, Medical, Encyclopedia.. Related to Albumin human: ... lactalbumin - albumin occurring in milk. serum albumin - albumin occurring in blood serum; serves to maintain the somatic ... albumen, albumin - Albumen is the white of an egg, from Latin albus, "white"; albumin is a protein within the albumen.. See ...

https://www.thefreedictionary.com/Albumin+human

A number of blood transport proteins are evolutionarily related, including serum albumin, alpha-fetoprotein , vitamin D-binding protein and afamin . (wikipedia.org)
Serum albumin is the main protein of human blood plasma. (wikipedia.org)
Albumin comprises three homologous domains that assemble to form a heart-shaped protein. (wikipedia.org)
Serum albumin is the most abundant blood plasma protein and is produced in the liver and forms a large proportion of all plasma protein. (wikipedia.org)
The human version is human serum albumin , and it normally constitutes about 50% of human plasma protein. (wikipedia.org)
Albumin is a protein produced by the liver and it forms an important part of the blood as it helps keep the water in the blood vessels and also helps carry many substances in the blood. (medhelp.org)
Albumin is a protein made by the liver. (labcorp.com)
Levels of albumin may decrease, to a greater or lesser degree, when conditions interfere with its production by the liver, increase protein breakdown, increase protein loss via the kidneys, and/or expand the volume of plasma, the liquid portion of blood (diluting the blood). (labcorp.com)
Human types include: Human serum albumin is the main protein of human blood plasma. (wikipedia.org)
Extracellular matrix protein 1 is a less canonical albumin. (wikipedia.org)
They are not in the same family as vertebrate albumins: Ovalbumin is a storage protein in egg white (albumen). (wikipedia.org)
Albumin is a 65-70 kDa protein. (wikipedia.org)
A serum albumin test measures the amount of this protein in the clear liquid portion of the blood. (medlineplus.gov)
Serum albumin, often referred to simply as blood albumin, is an albumin (a type of globular protein) found in vertebrate blood. (wikipedia.org)
Serum albumin is produced by the liver, occurs dissolved in blood plasma and is the most abundant blood protein in mammals. (wikipedia.org)
Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones in the blood and plays a major role in stabilizing extracellular fluid volume by contributing to oncotic pressure (known also as colloid osmotic pressure) of plasma. (wikipedia.org)
Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. (wikipedia.org)
Albumin is a globular, water-soluble, un-glycosylated serum protein of approximate molecular weight of 65,000 Daltons. (wikipedia.org)
Bovine serum albumin, or BSA, is commonly used in immunodiagnostic procedures, clinical chemistry reagents, cell culture media, protein chemistry research (including venom toxicity), and molecular biology laboratories (usually to leverage its non-specific protein binding properties). (wikipedia.org)
RCSB Protein Data Bank : Molecule of the Month - Serum Albumin Albumin binding prediction Overview of all the structural information available in the PDB for UniProt: P02768 (Human Serum albumin) at the PDBe-KB. (wikipedia.org)
Albumin is a protein produced by the liver that circulates in plasma (the clear liquid portion of your blood). (rexhealth.com)
Ovalbumin is the main protein of egg‐white, lactalbumin occurs in milk, and plasma or serum albumin is one of the major blood proteins. (encyclopedia.com)
Serum albumin concentration is sometimes measured as an index of protein‐energy malnutrition . (encyclopedia.com)
Human serum albumin (HSA) is the intravenous protein most commonly used in the world for therapeutic ends. (scienceblog.com)
Commercial albumin is currently extracted from blood, but the lack of sufficient reserves to cover all worldwide needs has instigated researchers to look for new formulae to multiply this protein. (scienceblog.com)
Albumin is a particularly suitable indicator of protein because it is neither synthesized nor metabolized intrathecally. (labcorp.com)
Albumin is the most prevalent protein in your blood, and without it, you can experience a number of symptoms. (livestrong.com)
The common causes of hypoproteinemia are protein-calorie malnutrition, defective absorption in gastro-intestinal disorders, faulty albumin synthesis in chronic hepatic failure, increased protein catabolism postoperatively or with sepsis, and abnormal renal losses of albumin with chronic kidney disease. (nih.gov)
Albumin Human is derived from human plasma, used to treat shock as a result of blood loss in the body (hypovolemia), burns, low protein levels (hypoproteinemia) due to surgery or liver failure, adult respiratory distress syndrome, dialysis, and as an additional medicine in bypass surgery. (medindia.net)
Albumin is a transport protein and it may be useful in severe jaundice in hemolytic disease of the newborn. (nih.gov)
albumin is a protein within the albumen. (thefreedictionary.com)
Results are expressed as a ratio (%) of glycated albumin to total albumin, thus minimizing differences in protein concentrations between patients. (news-medical.net)
Albumin makes up about 60% of the total protein. (labtestsonline.org)
Produced by the liver, albumin serves a variety of functions including as a carrier protein for many small molecules and ions, as a source of amino acids for tissue metabolism, and as the principle component involved in maintaining osmotic pressure (preventing fluid from leaking out of blood vessels). (labtestsonline.org)
Some laboratories report total protein, albumin, and the calculated ratio of albumin to globulins, termed the A/G ratio. (labtestsonline.org)
The A/G ratio is calculated from measured total protein, measured albumin, and calculated globulin (total protein - albumin). (labtestsonline.org)
Paclitaxel albumin-stabilized nanoparticle formulation is a form of paclitaxel contained in nanoparticles (very tiny particles of protein ). (cancer.gov)
Albumin is the most abundant protein in the blood. (labtestsonline.org.uk)
An albumin test checks urine for a protein called albumin . (cigna.com)
However, the magnitude of these responses is dependent upon dietary protein and is insufficient to normalize serum albumin. (nih.gov)
The Northwestern scientists are conducting a controlled study of a new "artificial liver" that uses albumin -- a protein that is produced naturally by the body and is a major component of human blood plasma -- to remove toxins from the blood of patients in chronic liver failure who are comatose. (eurekalert.org)
Human serum albumin (HSA) is an abundant plasma protein that binds a remarkably wide range of drugs, thereby restricting their free, active concentrations. (rcsb.org)
Serum albumin , often referred to simply as albumin , is the most abundant plasma protein in humans and other mammals. (bionity.com)
Bovine serum albumin, or BSA, is commonly used in immunodiagnostic procedures, clinical chemistry reagents, cell culture media, protein chemistry research and molecular biology laboratories. (bionity.com)
Albumin is a protein that is present in the blood. (labtestsonline.org.uk)
Too little albumin is present to be detected by the usual simple urine test strip (sometimes called a protein dipstick). (labtestsonline.org.uk)
This is termed microalbuminuria because of the low but significant concentration of albumin in the urine, not because it is a smaller type of the protein. (labtestsonline.org.uk)
Albumin is a protein made in the liver that has many functions in the body. (livestrong.com)
In the book "Krause's Food and Nutrition Therapy," author Mary D. Litchford reports that albumin accounts for around 60 percent of protein found in blood plasma, or the liquid part of blood. (livestrong.com)
In a few cases, severe protein-energy malnutrition may lead to decreased serum albumin levels. (livestrong.com)
More recently, science shows that low albumin is highly related to the disease state rather than nutritional status, so the effectiveness of eating a high-protein diet or drinking nutritional supplements is questionable. (livestrong.com)
There are forms of malnutrition, such as kwashiorkor, defined as chronic negligible protein calorie intake, where restoring adequate protein and calorie intake is important in improving albumin levels. (livestrong.com)
Aside from such cases, however, as long as you consume a balanced diet that includes adequate protein -- 0.8 g per kilogram per day for the average individual without illness -- the food you eat will likely not have an effect on your albumin level. (livestrong.com)
We examined the impact of sevoflurane and isoflurane on the dimerization of human serum albumin (HSA), a protein with anesthetic binding sites that are well characterized. (hindawi.com)
Albumin is a major protein normally present in blood, but virtually no albumin is present in the urine when the kidneys are functioning properly. (labtestsonline.org)
A healthy liver transforms the protein a person ingests into albumin. (medicalnewstoday.com)
If albumin levels are found to be too high, it may indicate a person is eating a high protein diet or is dehydrated. (medicalnewstoday.com)
Approximately 0.28 nanomole equivalent EDB/milligram protein was associated with albumin. (cdc.gov)
From blood to the lab: the protein albumin is responsible for many vital processes in the human body. (medindia.net)
Albumin is a protein that is found in large quantities in the blood of all mammals. (medindia.net)
When albumin deficit is the result of excessive protein loss, the effect of administration of albumin will be temporary unless the underlying disorder is reversed. (rxlist.com)
In most cases, increased nutritional replacement of amino acids and/or protein with concurrent treatment of the underlying disorder will restore normal plasma albumin levels more effectively than administration of albumin solutions. (rxlist.com)
In conjunction with appropriate crystalloid therapy, BUMINATE 5%, Albumin (Human), 5% Solution may be useful for treatment of protein deficits after the initial 24-hour period following extensive burns. (rxlist.com)
The interaction between captopril, an inhibitor of angiotensin converting enzyme and human serum albumin, a principal plasma protein in the liver has been investigated in vitro under a simulated physiological condition by UV-vis spectrophotometry and fluorescence spectrometry. (scirp.org)
No randomised or controlled trial was identified comparing albumin to crystalloids (other than normal saline) or non-protein colloids, or a combination of both, in the treatment of symptomatic hypotension during dialysis. (cochrane.org)
To compare the benefits and harms of volume expansion with human albumin, alone or in combination with crystalloid or non-protein colloids, for treating IDH in haemodialysis patients. (cochrane.org)
Bovine serum albumin (BSA) is used extensively as a carrier protein to dilute antibodies and as a general protein blocking agent in immunoassays and immunodetection protocols. (thomassci.com)
We offer two options for the BSA protein standards: Bovine Serum Albumin Standard BSA standard (2mg/ml) prepared in saline buffer. (thomassci.com)
Serum and plasma albumin is carbohydrate free and comprises 55-62% of the protein present. (thomassci.com)
Chicken egg albumin is the major protein constituent of egg whites. (thomassci.com)
Using affinity chromatography and surface plasmon resonance analysis, we have identified cubilin, a 460-kDa receptor heavily expressed in kidney proximal tubule epithelial cells, as an albumin binding protein. (jci.org)
Oxidation of human serum albumin (HSA), the major plasma protein, occurs in chronic kidney disease and leads to further activation of neutrophils. (clinicaltrials.gov)
Here we report adsorption properties of two carbon-based materials, thermally expanded graphite (EGr) and graphene nanoplatelets (GnP), for bovine serum albumin (BSA), the most abundant blood plasma protein. (mdpi.com)

In nephrotic syndrome, very high amounts of albumin are lost through the kidneys. (labcorp.com)
A symptom of high albumin levels is dehydration because your cells might be taking in more water to balance the higher amounts of albumin in your blood. (livestrong.com)
But when the kidneys are damaged, abnormal amounts of albumin leak into the urine. (cigna.com)
If early kidney damage is not treated, larger amounts of albumin may leak into the urine. (cigna.com)
When the kidneys are working properly, only tiny amounts of albumin pass from the bloodstream into the urine. (labtestsonline.org.uk)
A long time before this amount of damage, small changes in the kidney allow very small, but abnormal amounts of albumin to leak through, often as a result of having diabetes . (labtestsonline.org.uk)
Dogs with a functional defect in cubilin excrete large amounts of albumin in combination with virtually abolished proximal tubule reabsorption, showing the critical role for cubilin in the uptake of albumin by the proximal tubule. (jci.org)

The role of albumin in fluid balance and transport means low albumin levels can cause bodily problems that manifest in symptoms. (livestrong.com)
In order to investigate a possible role of albumin in regulating NETosis in vitro, we examined the effects of albumin depletion on cultured neutrophils. (nature.com)

The solid-phase antibody is reacted with a urine specimen, and the urine albumin-antigen complexes with the solid-phase antibody. (cdc.gov)
the fluorescence is directly proportional to the amount of urine albumin present. (cdc.gov)
Note: See Analytical Note on comparing the urine albumin-creatinine ratio of the random urine (first collection) and the follow-up first-morning void urine (second collection). (cdc.gov)
Urine albumin-creatinine ratio is used to classify stages of chronic kidney disease. (cdc.gov)
The ratio of urine albumin to urine creatinine is used to predict nephropathy risk in diabetic patients. (cdc.gov)
The urine albumin-antigen complexes with the solid-phase antibody. (cdc.gov)
The urine albumin test (formerly called microalbumin) detects and measures the amount of albumin in the urine to screen for kidney disease. (labtestsonline.org)

Sigma-Aldrich has partnered with the technology holders of recombinant human albumin products expressed in Rice, Pichia , and Saccharomyces to manufacture and distribute both research grade as well as custom bulk manufacturing grades. (sigmaaldrich.com)

Results of the fluorescent immunoassay (FIA) are reproducible, and the test is accurate and sensitive for the detection of human urinary albumin excretion. (cdc.gov)
Because urinary albumin excretion follows a circadian rhythym, the preferred method to collect urine for albumin assessment is to collect a 24 hour urine specimen. (cdc.gov)
Since the ACR depends not only on urinary albumin but also on urinary creatinine excretion, it will be affected by gender and age because muscle mass is lower in females than in males and decreases with age. (cdc.gov)
The nephrotic syndrome is characterized by the increased urinary excretion of albumin and of other serum proteins of intermediate molecular weight accompanied by a decrease in their serum concentration. (nih.gov)
In type 2 diabetics with microalbuminuria, irbesartan reduces albumin excretion independent of its antihypertensive effect. (diabetesincontrol.com)
Angiotensin-converting enzyme (ACE) inhibitors delay the progression from incipient to overt diabetic nephropathy and reduce albumin excretion rate (AER), independently of blood pressure,' write Ferdinando C. Sasso, MD, PhD, and colleagues from the Second University of Naples in Italy. (diabetesincontrol.com)
In addition, we find that mice lacking the endocytic receptor megalin show altered urinary excretion, and reduced tubular reabsorption, of albumin. (jci.org)
The rate constant for urinary excretion (k(10)) was slightly reduced by the preceding surgery, by a marked rise in plasma albumin, and by a high preinfusion urinary concentration of creatinine. (diva-portal.org)

Additionally, an albumin test may be ordered as part of a liver panel to evaluate liver function or with a creatinine , blood urea nitrogen (BUN) , or renal panel to evaluate kidney function. (labcorp.com)
Results of albumin testing are evaluated along with those from other tests done at the same time, such as the tests included in a CMP , basic metabolic panel (BMP) , liver panel , or renal panel . (labcorp.com)
This medicine is also used to treat low albumin levels caused by surgery, dialysis, abdominal infections, liver failure, pancreatitis, respiratory distress, bypass surgery, ovarian problems caused by fertility drugs, and other many other conditions. (rexhealth.com)
The liver then uses these proteins to create albumin, which is then circulated through the body. (livestrong.com)
Albumin also moves bilirubin, a yellow pigment and bile byproduct created in the liver, throughout your body. (livestrong.com)
Certain conditions such as liver disease can contribute to low albumin levels because liver disease impairs the body's ability to create proteins. (livestrong.com)
(1) This could also be of importance in acute liver failure where albumin might serve the dual role of supporting plasma oncotic pressure, as well as binding excessive plasma bilirubin. (nih.gov)
An albumin blood level test is typically done to test liver and kidney function. (reference.com)
Albumin is made in the liver and is extremely sensitive to liver damage. (labtestsonline.org.uk)
The concentration of albumin drops when the liver is damaged, when a person is malnourished, or if a person experiences inflammation in the body. (labtestsonline.org.uk)
CHICAGO --- Adding albumin to a dialysis solution may help patients wake up faster from coma due to chronic liver failure, according to researchers at Northwestern University Medical School. (eurekalert.org)
When the body is under inflammatory stress, the liver focuses on producing inflammatory proteins, like cytokines, rather than albumin. (livestrong.com)
In addition to decreased production by the liver, albumin that has already been produced and entered the bloodstream may be broken down for use in making proteins that will help fight the illness. (livestrong.com)
The TCA soluble fractions of kidney and liver tissues from rats injected with acrolein adducted albumin contained more radioactivity than those from rats injected with native albumin. (cdc.gov)
The authors conclude that the albumin/acrolein adduct is cleared more rapidly from the circulation and degraded more rapidly by the liver and kidney than native albumin. (cdc.gov)
Pseudo colored Green immunofluorescence staining of paraffin embedded rabbit liver with purified ab106582 Anti-Albumin at a working dilution of 1 in 100. (abcam.com)
If the results indicate an abnormal amount of albumin, it may suggest a problem with the liver or kidneys. (medicalnewstoday.com)
The liver releases albumin as part of its normal functioning. (medicalnewstoday.com)
When the liver is not functioning correctly, this process decreases and may lead to a drop in albumin levels. (medicalnewstoday.com)
A doctor will typically administer a serum albumin test if symptoms of liver disease or other liver problems are present. (medicalnewstoday.com)
In-vitro analysis involved incubation of human plasma or purified albumin with EDB in the presence of phenobarbital treated rat liver microsomes and an NADPH generating system for 2 hours. (cdc.gov)

Preoperative albumin to globulin ratio predicts survival in clear cell renal cell carcinoma patients. (urotoday.com)
In this retrospective analysis, we evaluated associations between albumin to globulin ratio (AGR), clinicopathological characteristics, and survival in 592 patients with localized or locally advanced clear cell renal cell carcinoma (CCRCC) prior to nephrectomy. (urotoday.com)
This observation is consistent with a hypothesis that increased renal catabolism contributes to total albumin catabolism in nephrosis. (nih.gov)
Effect of intravenous albumin on renal impairement and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. (medicin.dk)
What they showed was that if you had less than 30 mg of albumin in your urine, your chances of going onto end stage renal disease was zero, almost zero. (diabetesincontrol.com)
Also, by immunoblotting and immunocytochemistry we show that previously identified low-molecular-weight renal albumin binding proteins are fragments of cubilin. (jci.org)
This process may prove important for understanding interstitial renal inflammation and fibrosis caused by proximal tubule uptake of an increased load of filtered albumin. (jci.org)
Endotoxemia in renal insufficiency leads to impaired neutrophil function and to increased albumin oxidation. (clinicaltrials.gov)

albumin ( albumen ) A group of relatively small proteins which are soluble in water and readily coagulated by heat. (encyclopedia.com)
ALBUMIN , or Albumen (Lat. (wikisource.org)

It specifically measures both glycated albumin (enzymatic) and total albumin (BCP) in separate reactions. (news-medical.net)

A defect in this property results in nephrotic syndrome leading to albumin loss in the urine. (wikipedia.org)
Nephrotic syndrome patients are sometimes given albumin to replace the lost albumin. (wikipedia.org)
Metabolism of albumin and immunoglobulins in the nephrotic syndrome. (nih.gov)

AlbuRx ® 25, Albumin (Human) 25% solution is a sterile aqueous solution for intravenous administration containing the albumin component of human blood. (nih.gov)
AlbuRx ® 25, Albumin (Human) 25% solution should not be used as an intravenous nutrient because of the slow breakdown and relatively unfavorable composition of the albumin molecule with respect to its content of essential amino acids. (nih.gov)
Human serum albumin, at 2 g/kg, administered over 2 hours by intravenous infusion, will be compared to placebo (isovolumic normal saline) among patients with acute ischemic stroke. (clinicaltrials.gov)
BUMINATE 5%, Albumin (Human), 5% Solution is a sterile, nonpyrogenic preparation of albumin in a single dosage form for intravenous administration. (rxlist.com)
Aims A population kinetic model was developed for the body fluid shifts occurring when 20% albumin is given by intravenous infusion. (diva-portal.org)
Methods An intravenous infusion of 3 mL/kg 20% albumin over 30 minutes was given to 15 volunteers and to 15 patients on the 1(st) day after major open abdominal surgery. (diva-portal.org)

Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated . (wikipedia.org)
Serum albumins are important in regulating blood volume by maintaining the oncotic pressure (also known as colloid osmotic pressure ) of the blood compartment. (wikipedia.org)
Albumins are widely distributed in plant and animal tissues, e.g., ovalbumin of egg, myogen of muscle, serum albumin of blood, lactalbumin of milk, legumelin of peas, and leucosin of wheat. (factmonster.com)
Separation of serum albumins from other blood proteins can be carried out by electrophoresis or by fractional precipitation with various salts. (factmonster.com)
Albumins and other proteins of the blood aid significantly in regulating the distribution of water and maintenance of proper osmotic pressure in the body. (factmonster.com)
This test measures the level of albumin in the blood. (labcorp.com)
Albumin keeps fluid from leaking out of blood vessels, nourishes tissues, and transports hormones, vitamins, drugs, and substances like calcium throughout the body. (labcorp.com)
Albumin is present in high concentrations in the blood, and when the kidneys are functioning properly, virtually no albumin is lost in the urine. (labcorp.com)
Paclitaxel (with albumin) injection may cause a large decrease in the number of white blood cells (a type of blood cell that is needed to fight infection) in your blood. (medlineplus.gov)
You should not receive paclitaxel (with albumin) if you already have a low number of white blood cells. (medlineplus.gov)
without albumin, the high pressure in the blood vessels would force more fluids out into the tissues. (wikipedia.org)
Because smaller animals (for example rats) function at a lower blood pressure, they need less oncotic pressure to balance this[citation needed], and thus need less albumin to maintain proper fluid distribution. (wikipedia.org)
The general structure of albumin is characterized by several long α helices allowing it to maintain a relatively static shape, which is essential for regulating blood pressure. (wikipedia.org)
Blood plasma fractionation Bovine serum albumin Chromatography in blood processing Human serum albumin Lactalbumin Ovalbumin Sugio S, Kashima A, Mochizuki S, Noda M, Kobayashi K (June 1999). (wikipedia.org)
You should not receive albumin if you have severe anemia (lack of red blood cells), or severe heart failure. (rexhealth.com)
Medicinal albumin is made of plasma proteins from human blood. (rexhealth.com)
This medicine works by increasing plasma volume or levels of albumin in the blood. (rexhealth.com)
Albumin is used to replace blood volume loss resulting from trauma such as a severe burns or an injury that causes blood loss. (rexhealth.com)
Albumin is made from human plasma (part of the blood) which may contain viruses and other infectious agents. (rexhealth.com)
Your breathing, pulse, blood pressure, electrolyte levels, kidney function, and other vital signs will be watched closely while you are receiving albumin. (rexhealth.com)
The degree of permeability of the blood-brain barrier can be evaluated by the quantitative measurements of albumin in the CSF and the serum on specimens obtained at the same time. (labcorp.com)
In CSF that is free of blood contamination, therefore, albumin must necessarily have come from plasma through the blood-brain barrier. (labcorp.com)
If your physician suspects you might not have enough albumin in your body, he can perform a blood test to determine your range and recommend treatments to correct albumin levels. (livestrong.com)
To maintain normal blood albumin ranges, you should have between 3.4 and 5.4 g/dL of albumin in your blood. (livestrong.com)
The albumin in your blood moves the mineral calcium, the hormone progesterone and medicines throughout your tissues. (livestrong.com)
16 The two main indications for the use of AlbuRx ® 25, Albumin (Human) 25% solution are therefore a plasma or blood volume deficit and the oncotic deficit resulting from hypoproteinemia. (nih.gov)
In such circumstances, the use of albumin infusion may be required to support the blood volume. (nih.gov)
Two classes of proteins are found in the blood, albumin and globulin. (labtestsonline.org)
Albumin is normally found in the blood and filtered by the kidneys. (cigna.com)
With MARS, toxic substances in the blood bind to the albumin, cross into the dialysis solution and are therefore removed from the body. (eurekalert.org)
Basically, this means that albumin is highly responsible for keeping water inside of blood vessels. (livestrong.com)
The neurotoxicity of albumin could be of importance in disease states which are accompanied by leakiness of the blood-brain barrier. (nih.gov)
However, one blood test for albumin about 10 days after surgery was a little low (3.0g/dL) but I had been suffering from diarrhea for a week from the cephalosporin antibiotics they were pumping into me and I didn't get any food to eat for approx. (rutgers.edu)
The serum albumin test looks at the levels of albumin in a person's blood. (medicalnewstoday.com)
Albumin is one of the most abundant proteins found in the blood. (medicalnewstoday.com)
A doctor will order a blood test, which will include a serum albumin element. (medicalnewstoday.com)
Typically, the range for albumin in the blood is between 3.4 to 5.4 grams per deciliter. (medicalnewstoday.com)
The serum albumin test requires only a small amount of blood. (medicalnewstoday.com)
BUMINATE 5%, Albumin (Human), 5% Solution contains no blood group isoagglutinins thereby permitting its administration without regard to the recipient 's blood group. (rxlist.com)
Because albumin is a relatively rare and expensive blood product, we asked if albumin had an advantage over other fluids to treat IDH. (cochrane.org)

All the proteins of the albumin family are water- soluble , moderately soluble in concentrated salt solutions, and experience heat denaturation . (wikipedia.org)

Serum albumin test: Why is it done and what do the results mean? (medicalnewstoday.com)
What does a serum albumin test tell you? (medicalnewstoday.com)
A doctor will often request a serum albumin test as part of a metabolic panel. (medicalnewstoday.com)
A doctor may use the serum albumin test in other cases to monitor existing conditions, such as kidney disease or chronic pancreatitis . (medicalnewstoday.com)
A serum albumin test does not usually require people to fast. (medicalnewstoday.com)
Since the serum albumin test is often one of several tests administered at any one time, a doctor will interpret all the results together to determine if any underlying conditions exist. (medicalnewstoday.com)

Can Nutrition Increase Albumin Levels? (livestrong.com)
Historically, albumin has been used as a marker of nutritional status, so often nutritional supplements would be prescribed to help increase albumin levels. (livestrong.com)

Older studies in septic patients, however, did not show any benefit of albumin over saline solution. (clinicaltrials.gov)
Solutions of rat albumin (3, 10 and 30 mg/ml) essentially free of fatty acids and globulins were injected into one neostriatum, physiological saline into the other. (nih.gov)
Thus 3, 10 and 30 mg/ml albumin produced lesions in excess of saline of 22 +/- 24 microns3, 67 +/- 25 microns3 and 170 +/- 44 microns3, (P = 0.82, 0.03 and 0.0005, respectively). (nih.gov)
Injection of 10 mg/ml albumin together with 10 mM sodium glutamate caused lesions of 70 +/- 11 microns3 in excess of saline (P = 0.005). (nih.gov)
This bottle contains 12.5 g albumin from venous plasma in saline and is osmotically equivalent to an equal volume of normal human plasma. (rxlist.com)
These can include saline, albumin or other fluids such as gelatins and starches. (cochrane.org)
This trial showed no difference between albumin and normal saline in all outcomes except for the amount of additional saline given, which was less in the group treated with albumin. (cochrane.org)
Results from 45 assessable participants did not lead to rejection of the null hypothesis of no difference between 5% albumin and normal saline in the primary outcome measure of percentage target ultrafiltration achieved, nor in 11/12 secondary outcomes. (cochrane.org)
Additional ( unblinded ) saline was given less often when 5% albumin was used compared with saline (16% versus 36%, P = 0.04). (cochrane.org)

Albumin Antibody in. (bmj.com)
The fluorescent immunoassay is a non-competitive, double-antibody method for the determination of human albumin in urine. (cdc.gov)
Antibody to human albumin is covalently attached to derivatized polyacrylamide beads. (cdc.gov)

Occasionally albumin appears in the urine of normal persons following long periods of standing (postural albuminuria). (wikipedia.org)
Microalbuminuria" is slowly being replaced with the term "albuminuria," which refers to any elevation of albumin in the urine. (labtestsonline.org)

For the specific albumins found in vertebrate bloodstreams, see serum albumin . (wikipedia.org)

Drinking too much water (water intoxication) may also cause abnormal albumin results. (medlineplus.gov)
If the amount of albumin is very small, but still abnormal, it is called microalbuminuria. (cigna.com)
People are at a higher risk for abnormal levels of albumin if they have an open wound or burn or following surgery. (medicalnewstoday.com)

2018. "Adsorption of Bovine Serum Albumin on Carbon-Based Materials. (mdpi.com)

When the kidneys are working as they should, there may be a very small amount of albumin in the urine. (cigna.com)
This is because the amount of albumin can change, depending on how much water is in your urine. (cigna.com)
The presence of a small amount of albumin in the urine may be an early indicator of kidney disease. (labtestsonline.org)
A small amount of albumin in the urine is sometimes referred to as urine microalbumin or microalbuminuria. (labtestsonline.org)

With the aid of infrared spectroscopy the group is now able to demonstrate how the structure of albumin changes when exposed to heat. (medindia.net)

Another option worked on over recent years has been the production of albumin from vegetables, always using nuclear transformation. (scienceblog.com)
A property highly valued by the experts has to be added to these positive results: the production of albumin from plants using this technique does not involve the escape of genes through pollen transmission given that, with most crops under cultivation, the genome of the plastids is inherited maternally. (scienceblog.com)

Since the oncotic pressure of AlbuRx ® 25, Albumin (Human) 25% solution is about four times higher than that of normal human serum, it will expand the plasma volume if interstitial water is available for an inflow through the capillary walls. (nih.gov)
Albumin synthesis is increased at the level of mRNA synthesis in response to decreased serum oncotic pressure. (nih.gov)
In addition to being the major transport vessel for various hormones, enzymes, minerals, fatty acids and other metabolites, the main function of albumin is to maintain something known as oncotic pressure. (livestrong.com)

The four canonical human albumins are arranged on chromosome 4 region 4q13.3 in a tandem manner. (wikipedia.org)

It's a smaller molecule of albumin. (diabetesincontrol.com)
It's a small albumin molecule. (diabetesincontrol.com)

If you do lose albumin in your body, the fluid can leak into your tissues and cause swelling. (livestrong.com)
Albumins are a group of acidic proteins which occur in the body fluids and tissues of mammals and in some plant seeds. (thomassci.com)
96%, white lyophilized powder Synonyms: BSA, Bovine albumin Albumins are a group of acidic proteins which occur plentifully in the body fluids and tissues of mammals and in some plant seeds. (thomassci.com)

High albumin ( hyperalbuminemia ) is almost always caused by dehydration. (wikipedia.org)

Abstract We will evaluate four photoactivatable fatty acid analogs and three photoactivatable C16 alkylchain derivatives for their ability to derivatize to four representative biomaterials and subsequently adsorbhuman albumin. (sbir.gov)

Your doctor will order certain tests to check your body's response to paclitaxel (with albumin) injection. (medlineplus.gov)
Talk to your doctor about the risks of receiving paclitaxel (with albumin) injection. (medlineplus.gov)
Paclitaxel (with albumin) injection is used to treat breast cancer that has spread to other parts of the body and has not improved or worsened after treatment with other medications. (medlineplus.gov)
Paclitaxel (with albumin) injection is also used in combination with other chemotherapy medications to treat non-small cell lung cancer (NSCLC). (medlineplus.gov)
Paclitaxel (with albumin) injection is used in combination with gemcitabine (Gemzar) to treat cancer of the pancreas. (medlineplus.gov)
Paclitaxel (with albumin) injection comes as a powder to be mixed with liquid to be injected over 30 minutes intravenously (into a vein) by a doctor or nurse in a medical facility. (medlineplus.gov)
When paclitaxel (with albumin) injection is used to treat breast cancer, it is usually given once every 3 weeks. (medlineplus.gov)
When paclitaxel (with albumin) injection is used to treat non-small cell lung cancer it is usually given on days 1, 8, and 15 as part of a 3 week cycle. (medlineplus.gov)
Albumin human 25% solution for injection vial or plastic bag 50ml. (thefreedictionary.com)

A primed-constant infusion of a stable isotopic tracer of phenylalanine was used to determine hepatic fractional synthetic rate (FSR) and absolute synthetic rate (ASR) of albumin from the enrichment of phenylalanine in albumin. (nih.gov)
Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials. (medicin.dk)

Kidney disease-one of the many functions of the kidneys is to conserve plasma proteins such as albumin so that they are not released along with waste products when urine is produced. (labcorp.com)
Albumin in the urine usually denotes the presence of kidney disease. (wikipedia.org)
When the kidneys spill albumin, it can mean serious kidney damage is present. (cigna.com)
Like albumin, IgG is lost in the urine, its serum concentration is decreased, and the fractional rate of its catabolism is increased, suggesting that the kidney contributes to IgG catabolism in the presence of proteinuria. (nih.gov)
However, albumin may be detected in the urine even in the early stages of kidney disease . (labtestsonline.org)
This concept will change the understanding of several aspects of chronic kidney disease and will potentially help to stratify patients into different groups at risk according to their endotoxin status, and their immune and albumin dysfunction. (clinicaltrials.gov)

My 15 year old's results: albumin 4.71 globulin 2.23 a/g ratio 2.11 bilirubin total. (medhelp.org)
The binding properties of albumin may provide an indication for its use in severe hemolytic disease of the newborn, where it may lower the plasma concentration of free bilirubin pending an exchange transfusion. (nih.gov)
W.J. Cashore, W. Oh, and R. Brodersen, Reserve albumin and bilirubin toxicity index in infant serum, Acta Pædiatr. (springer.com)
F. Ebbesen, Effect of exchange transfusion on serum reserve albumin for binding of bilirubin and index of serum bilirubin toxicity, Acta Pædiatr. (springer.com)
F. Ebbesen, The relationship between serum bilirubin and reserve albumin for binding of bilirubin during phototherapy of preterm infants, Acta Pædiatr. (springer.com)
F. Ebbesen, Bilirubin, reserve albumin for binding of bilirubin and pH in plasma during phototherapy (ordinary and double light) of term newborn infants, Acta Pædiatr. (springer.com)

Agricultural engineer, Alicia Fernández San Millán, has developed a novel technique in Spain - plastidial transformation, in order to produce, in a recombinant form, human albumin from tobacco plants. (scienceblog.com)
Please inquire about custom formulations with Recombinant Albumin, which can be utilized in vaccine development. (neb.com)
Recombinant Albumin, Molecular Biology Grade, is a non-bovine derived albumin that can serve as an alternative to Bovine Serum Albumin (BSA). (neb.com)
Choose Recombinant Albumin, when there is a need to avoid BSA. (neb.com)
Equivalent stability performance between BSA and Recombinant Albumin. (neb.com)
BSA and Recombinant Albumin are used to stabilize enzymes in a reaction. (neb.com)
NcoI-HF ( NEB #R3193 ) was formulated with either BSA, Molecular Biology Grade or Recombinant Albumin and then stored at -20°C for 2 years. (neb.com)
The data shows equivalency between enzyme formulated with BSA, Molecular Biology Grade and Recombinant Albumin. (neb.com)
Recombinant Albumin that can serve as an alternative to BSA, which can prevent adhesion of enzymes to reaction tubes and pipette surfaces as well as stabilizes some proteins during incubation. (neb.com)
Please inquire about custom formulations with Recombinant Albumin. (neb.com)

However, since albumin levels respond to a variety of conditions in addition to malnutrition, a decrease in albumin needs to be evaluated carefully. (labcorp.com)
If he finds that you have low albumin due to malnutrition, adequate nutrition will be integral in getting your body back to health. (livestrong.com)
The doctor is now claiming that one low albumin level on that one particular day indicated I was suffering from malnutrition and that is one of the reasons my surgery failed. (rutgers.edu)

Albumin plays a major role in maintaining fluid balance in your body. (livestrong.com)
In addition to its role in maintaining fluid balance, albumin also acts as a transport vessel. (livestrong.com)
Increased albumin content and reduced free water clearance contribute to a retention of fluid within the circulation after intense exercise. (nih.gov)
A remarkable change occurs when many albumins are boiled with water, or treated with certain acids, their solubility and general characters being entirely altered, and the fluid becoming coagulated. (wikisource.org)
The use of this ratio allows the albumin concentration to be related to the dilution of urine (as indicated by the creatinine concentration) which can depend on how much fluid you have consumed that day. (labtestsonline.org.uk)
Albumin maintains the fluid balance in the body. (medicalnewstoday.com)

Substances containing albumins, such as egg white , are called albuminoids . (wikipedia.org)
Substances containing albumins are called albuminoids. (wikipedia.org)
The vegetable kingdom is the original source of albuminous substances, the albumins being found in greatest quantity in the seed. (wikisource.org)

However, if a person's kidneys become damaged or diseased, they begin to lose their ability to conserve albumin and other proteins. (labcorp.com)

Urinary albumin and urinary creatinine are measured in a random urine collected in the MEC. (cdc.gov)
Urinary albumin and urinary creatinine are measured in a random urine collected in the MEC (first collection) and a first morning void urine collected by the participant at home (second collection). (cdc.gov)
Therefore, measurement of urinary albumin and creatinine concentrations are performed and an albumin:creatinine ratio (ACR) was determined from both a random urine and a first morning void. (cdc.gov)
ACR measurement in random urine samples has been shown to be just as good as the measurement of albumin alone in 24 hour urine samples and is much more convenient for the person being tested. (labtestsonline.org.uk)
This property of creatinine allows its measurement to be used to correct for urine concentration when measuring albumin in a random urine sample. (labtestsonline.org)

When the hypovolemia is long-standing and hypoalbuminemia exists accompanied by adequate hydration or edema, treatment with BUMINATE 25%, Albumin (Human), 25% Solution is preferable. (rxlist.com)
Hypoalbuminemia is another possible indication for use of BUMINATE 5%, Albumin (Human), 5% Solution. (rxlist.com)
Occasionally hypoalbuminemia accompanying severe injuries, infections or severe pancreatitis cannot be quickly reversed and nutritional supplements may fail to restore adequate plasma albumin levels. (rxlist.com)

tell your doctor and pharmacist if you are allergic to paclitaxel, docetaxel, any other medications, or human albumin, Ask your doctor or pharmacist if you do not know if a medication that you are allergic to contains human albumin. (medlineplus.gov)
This page contains brief information about paclitaxel albumin-stabilized nanoparticle formulation and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials. (cancer.gov)
Paclitaxel albumin-stabilized nanoparticle formulation is also being studied in the treatment of other types of cancer . (cancer.gov)
For more information about paclitaxel that may apply to paclitaxel albumin-stabilized nanoparticle formulation, see the Drug Information Summary for Paclitaxel . (cancer.gov)
Find Clinical Trials for Paclitaxel Albumin-stabilized Nanoparticle Formulation - Check for trials from NCI's list of cancer clinical trials now accepting patients. (cancer.gov)
The clinical trials on this list are studying Paclitaxel Albumin-Stabilized Nanoparticle Formulation. (cancer.gov)

Serum albumin is widely distributed in mammals. (wikipedia.org)

When serum albumin levels decrease, the water in the plasma seeps into the empty space surrounding the cells where water doesn't usually collect, leading to swelling. (livestrong.com)
Another important impact of HSA oxidation is the decrease of its binding capacity leading to impaired detoxification ability of albumin. (clinicaltrials.gov)

Fatty Acid Free, ≥98%, Off-white Powder, sometimes with greenish hue Albumin bovine fraction V is the only commercially available Bovine Serum Albumin that is essentially fatty acid free. (thomassci.com)

Urinary albumin and creatinine are measured. (cdc.gov)

Anatomy6

Organisms5

Diseases15

Chemicals and Drugs48

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Phenomena and Processes17

Health Care1

Isolation of rat liver albumin messenger RNA. (1/2483)

Sentinel lymph node biopsy and axillary dissection in breast cancer: results in a large series. (2/2483)

"The FSGS factor:" enrichment and in vivo effect of activity from focal segmental glomerulosclerosis plasma. (3/2483)

Triacylglycerol biosynthesis in rat adipose-tissue homogenates. (4/2483)

von Willebrand factor contained in a high purity FVIII concentrate (Fanhdi) binds to platelet glycoproteins and supports platelet adhesion to subendothelium under flow conditions. (5/2483)

Secretory cells of the peripheral pulmonary epithelium as targets for toxic agents. (6/2483)

Peritoneal clearance of leptin in CAPD patients: impact of local insulin administration. (7/2483)

The cytotoxicity of mafosfamide on G-CSF mobilized hematopoietic progenitors is reduced by SH groups of albumin--implications for further purging strategies. (8/2483)

Albumins

Serum Albumin

Serum Albumin, Bovine

Serum Albumin, Radio-Iodinated

Receptors, Albumin

Technetium Tc 99m Aggregated Albumin

Albuminuria

Hypoalbuminemia

2S Albumins, Plant

Blood Proteins

Bromcresol Green

Bilirubin

Capillary Permeability

Liver

Cattle

Protein Binding

alpha-Fetoproteins

Plasma Volume

Creatinine

Dialysis

Blood Protein Electrophoresis

Plasma Substitutes

Proteinuria

Diabetic Nephropathies

Kinetics

Bromcresol Purple

Time Factors

Nephelometry and Turbidimetry

Renal Dialysis

Transferrin

Kidney Failure, Chronic

Rabbits

Biological Markers

Orosomucoid

Serum Globulins

Hydrogen-Ion Concentration

Kidney

Ultrafiltration

Kidney Glomerulus

Rats, Inbred Strains

Colloids

Protein-Losing Enteropathies

Nephrotic Syndrome

Protein-Energy Malnutrition

Adsorption

Immunoglobulin G

Hydroxyethyl Starch Derivatives

Fibrinogen

Nutritional Status

Fructosamine

Glomerular Filtration Rate

Low Density Lipoprotein Receptor-Related Protein-2

Binding Sites

Spectrometry, Fluorescence

Biological Transport

Electrophoresis, Polyacrylamide Gel

Oleic Acids

Cells, Cultured

Hematocrit

Rats, Sprague-Dawley

Hypoproteinemia

Proteins

Urea

Radioimmunoassay

Reference Values

Carbonates

Fatty Acids

Globulins

Chromatography, High Pressure Liquid

Perfusion

Glycosylation End Products, Advanced

Blood Chemical Analysis

Evans Blue

Iodine Radioisotopes

Kidney Diseases

Fluorescein-5-isothiocyanate

Kidney Tubules, Proximal

Iodine Isotopes

Immunoelectrophoresis

Antibodies

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