Albendazole
Anthelmintics
Mebendazole
Echinococcosis
Ivermectin
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
Diethylcarbamazine
Echinococcus
Echinococcosis, Hepatic
Liver disease caused by infections with parasitic tapeworms of the genus ECHINOCOCCUS, such as Echinococcus granulosus or Echinococcus multilocularis. Ingested Echinococcus ova burrow into the intestinal mucosa. The larval migration to the liver via the PORTAL VEIN leads to watery vesicles (HYDATID CYST).
Ascariasis
Echinococcus granulosus
Ascaris lumbricoides
Elephantiasis, Filarial
Antinematodal Agents
Hookworm Infections
Neurocysticercosis
Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50)
Wuchereria bancrofti
Encephalitozoonosis
Strongyloidiasis
Strongylida
Intestinal Diseases, Parasitic
Encephalitozoon
Antiplatyhelmintic Agents
Echinococcosis, Pulmonary
Cysticercosis
Strongyloides stercoralis
Helminths
Larva Migrans
Eye Infections, Parasitic
Filariasis
Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.
Loiasis
A parasitic infection caused by the nematode Loa loa. The vector in the transmission of this infection is the horsefly (Tabanus) or the deerfly or mango fly (Chrysops). The larvae may be seen just beneath the skin or passing through the conjunctiva. Eye lesions are not uncommon. The disease is generally mild and painless.
Microfilaria
Thiabendazole
Taenia solium
Angiostrongylus cantonensis
Ancylostomatoidea
Encephalitozoon cuniculi
Gnathostoma
Microsporida
Trichinellosis
An infection with TRICHINELLA. It is caused by eating raw or undercooked meat that is infected with larvae of nematode worms TRICHINELLA genus. All members of the TRICHINELLA genus can infect human in addition to TRICHINELLA SPIRALIS, the traditional etiological agent. It is distributed throughout much of the world and is re-emerging in some parts as a public health hazard and a food safety problem.
Drug Therapy, Combination
Feces
Giardia lamblia
Persistent damage to Enterocytozoon bieneusi, with persistent symptomatic relief, after combined furazolidone and albendazole in AIDS patients. (1/555)
AIM: To investigate morphological changes in Enterocytozoon bieneusi and the duration of symptomatic relief after combination treatment with furazolidone and albendazole in AIDS patients. METHODS: Four severely immunocompromised AIDS patients with symptomatic E bieneusi infection of the gut received an 18 day course of combined furazolidone and albendazole (500 + 800 mg daily). All patients were monitored for parasite shedding in stool by light microscopy at the end of treatment and monthly during follow up. At the end of treatment, duodenal biopsy specimens obtained from three patients were studied by transmission electron microscopy by two pathologists blind to the patients' treatment or clinical outcome. Duodenal biopsy specimens obtained from one of the patients two months after completion of treatment were also studied electronmicroscopically. RESULTS: All patients had long lasting symptomatic relief, with a major decrease--or transient absence--of spore shedding in stools from completion of treatment. After treatment, changes in faecal spores were persistently found by light microscopy in all cases, and there was evidence of both a substantial decrease in the parasite load and ultrastructural damage in the parasite in all biopsy specimens. The treatment was well tolerated, and no patient had clinical or parasitological relapse during follow up (up to 15 months). CONCLUSIONS: The long lasting symptomatic relief observed in all four treated patients correlated with the persistent decrease in parasite load both in tissue and in stool, and with the morphological changes observed in the life cycle of the protozoan. These data suggest that combined treatment with furazolidone and albendazole is active against E bieneusi and may result in lasting remission even in severely immunocompromised patients. (+info)Double-blind placebo-controlled study of concurrent administration of albendazole and praziquantel in schoolchildren with schistosomiasis and geohelminths. (2/555)
A double-blind placebo-controlled study of the concurrent administration of albendazole and praziquantel was conducted in>1500 children with high prevalences of geohelminths and schistosomiasis. The study sites were in China and the Philippines, including 2 strains of Schistosoma japonicum, and 2 different regions of Kenya, 1 each with endemic Schistosoma mansoni or Schistosoma haematobium. Neither medication affected the cure rate of the other. There was no difference between the side effect rate from albendazole or the double placebo. Praziquantel-treated children had more nausea, abdominal pain, and headache but these side effects were statistically more common in children with schistosomiasis, suggesting a strong influence of dying parasites. The subjects were followed for 6 months for changes in infection status, growth parameters, hemoglobin, and schistosomiasis morbidity. In all 4 sites, a significant 6-month increase in serum hemoglobin was observed in children who received praziquantel, strongly supporting population-based mass treatment. (+info)Neurocysticercosis in an Italian traveler to Latin America. (3/555)
Neurocysticercosis is rarely reported in short-term travelers, although the disease remains a major public health problem in tropical regions. We present a case of neurocysticercosis that was probably acquired by ingestion of Taenia solium eggs contained in the stomach of a pig butchered by the traveler. Complete clinical resolution was obtained by medical treatment, underlying the importance of early suspicion and diagnosis of the disease. (+info)The cost effectiveness of strategies for the treatment of intestinal parasites in immigrants. (4/555)
BACKGROUND: Currently, more than 600,000 immigrants enter the United States each year from countries where intestinal parasites are endemic. At entry persons with parasitic infections may be asymptomatic, and stool examinations are not a sensitive method of screening for parasitosis. Albendazole is a new, broad-spectrum antiparasitic drug, which was approved recently by the Food and Drug Administration. International trials have shown albendazole to be safe and effective in eradicating many parasites. In the United States there is now disagreement about whether to screen all immigrants for parasites, treat all immigrants presumptively, or do nothing unless they have symptoms. METHODS: We compared the costs and benefits of no preventive intervention (watchful waiting) with those of universal screening or presumptive treatment with 400 mg of albendazole per day for five days. Those at risk were defined as immigrants to the United States from Asia, the Middle East, sub-Saharan Africa, Eastern Europe, and Latin America and the Caribbean. Cost effectiveness was expressed both in terms of the cost of treatment per disability-adjusted life-year (DALY) averted (one DALY is defined as the loss of one year of healthy life to disease) and in terms of the cost per hospitalization averted. RESULTS: As compared with watchful waiting, presumptive treatment of all immigrants at risk for parasitosis would avert at least 870 DALYs, prevent at least 33 deaths and 374 hospitalizations, and save at least $4.2 million per year. As compared with watchful waiting, screening would cost $159,236 per DALY averted. CONCLUSIONS: Presumptive administration of albendazole to all immigrants at risk for parasitosis would save lives and money. Universal screening, with treatment of persons with positive stool examinations, would save lives but is less cost effective than presumptive treatment. (+info)Serum cytokine detection in the clinical follow up of patients with cystic echinococcosis. (5/555)
The relation of serum cytokine levels and outcome of chemotherapy was evaluated in 15 patients with cystic echinococcosis. Serum IL-4, IL-10 and interferon-gamma (IFN-gamma) concentrations were determined by ELISA before and after a 3-month course of albendazole treatment: at least one serum sample per patient from 13 patients (87%) contained measurable amounts of IL-4; samples from five patients (33%) measurable amounts of IL-10 and samples from only two patients (13%) measurable amounts of IFN-gamma. Clinical assessment at 1 year after the end of therapy showed that 11 of the 15 patients had responded clinically. Seven of these patients had lower IL-4 serum concentrations, two had unchanged and two undetectable amounts (pre- versus post-therapy, n = 11, P = 0.008). Conversely, of the patients who did not respond, three had higher and one patient unchanged serum IL-4 concentrations. Serum IL-10 10 levels also decreased in all patients who responded (3/5) and increased in all patients who did not (2/5). No association was found between cytokine concentrations and cyst characteristics or antibody levels. Overall these data suggest that serum IL-4 detection may be useful in the follow up of patients with cystic echinococcosis. (+info)Efficacies of albendazole sulfoxide and albendazole sulfone against In vitro-cultivated Echinococcus multilocularis metacestodes. (6/555)
The metacestode stage of Echinococcus multilocularis is the causative agent of alveolar echinococcosis (AE), a parasitic disease affecting the liver, with occasional metastasis into other organs. Benzimidazole carbamate derivatives such as mebendazole and albendazole are currently used for chemotherapeutic treatment of AE. Albendazole is poorly resorbed and is metabolically converted to its main metabolite albendazole sulfoxide, which is believed to be the active component, and further to albendazole sulfone. Chemotherapy with albendazole has been shown to have a parasitostatic rather than a parasitocidal effect; it is not effective in all cases, and the recurrence rate is rather high once chemotherapy is stopped. Thus, development of new means of chemotherapy of AE is needed. This could include modifications of benzimidazoles and elucidiation of the respective biological pathways. In this study we performed in vitro drug treatment of E. multilocularis metacestodes with albendazole sulfoxide and albendazole sulfone. High-performance liquid chromatography analysis of vesicle fluids showed that the drugs were taken up rapidly by the parasite. Transmission electron microscopic investigation of parasite tissues and nuclear magnetic resonance spectroscopy of vesicle fluids demonstrated that albendazole sulfoxide and albendazole sulfone had similar effects with respect to parasite ultrastructure and changes in metabolites in vesicle fluids. This study shows that the in vitro cultivation model presented here provides an ideal first-round test system for screening of antiparasite drugs. (+info)Cost of school-based drug treatment in Tanzania. The Partnership for Child Development. (7/555)
It has been argued that targeting delivery of anthelmintics to school-children by taking advantage of the existing education infrastructure and administrative system can be one of the most cost-effective approaches in minimizing the intensity of infections with both schistosomiasis and major intestinal nematodes in many developing countries. The study was conducted in January 1997, shortly after the completion of the drug intervention programme. This paper provides an analysis of the costs of providing age-targeted treatment of school-children for urinary schistosomiasis using praziquantel and for intestinal nematodes using albendazole as an integral part of the School Health Programme in Tanga Region, Tanzania. The analysis shows that the total financial cost of the intervention programme in 1996 prices was US$54 252.28 (exchange rate: TSH 573 = US$1). Of this amount, the cost of drugs constitutes 80.6%, while the delivery cost appears relatively low, representing just below 20%. Even when the opportunity cost of unpaid days of labour input is included, the cost of drugs still remains the highest cost component of the intervention (55.8%). In the current epidemiological and logistic setting of Tanzania, the financial cost per child treated using praziquantel, which involved prior screening at the school level, was US$0.79, while treatment using albendazole was as low as US$0.23, of which US$0.20 was drug purchase cost. It is concluded that the base cost of delivering a universal, standard, school-based health intervention such as albendazole can be as low as US$0.03 per child tested, but even a very slight increase in the complexity of delivery can have a very significant impact on the cost of intervention. (+info)Evidence for an improvement in cognitive function following treatment of Schistosoma japonicum infection in Chinese primary schoolchildren. (8/555)
A double-blind, placebo-controlled, treatment trial was conducted in Sichuan, China to investigate the unique and combined effects on the cognitive function (working memory) of children after treating geohelminth infections with albendazole and treating Schistosoma japonicum infection with praziquantel. One hundred eighty-one children 5-16 years of age participated. At baseline, the praziquantel and placebo groups were similar in all background characteristics. Three months after praziquantel treatment, there was a significant reduction in the prevalence and intensity of S. japonicum infection. There were significant age group by praziquantel treatment interaction effects in three of the five cognitive tests, Fluency, Picture Search, and Free Recall, with effects being strongest in the youngest children (5-7 years old). Exploratory analysis within the youngest children showed a significant positive main effect of treatment on Fluency (P < 0.001), after controlling for sex, anthropometric, and parasitic and iron status. There was also a treatment by height-for-age interaction (P = 0.03) and a treatment by iron status interaction (P = 0.024) on Fluency. There was a treatment by S. japonicum intensity interaction (P < 0.001) on Free Recall, but the main effect of treatment on Picture Search was not significant (P = 0.058). Younger children and those who are physically the most vulnerable are likely to benefit the most from the treatment of S. japonicum infection in terms of improved performance on tests of working memory. (+info)
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Albendazole
... was developed in 1975. It is on the World Health Organization's List of Essential Medicines. Albendazole is an ... For systemic parasites, albendazole acts as a prodrug, while albendazole sulfoxide reaches systemic circulation and acts as the ... Albendazole sulfoxide is converted to the inactive albendazole sulfone by cytochrome P450 oxidases, thought to include CYP3A4 ... While studies in pregnant rats and rabbits have shown albendazole to be teratogenic, albendazole has been found to be safe in ...
Albendazole monooxygenase
In enzymology, an albendazole monooxygenase (EC 1.14.13.32) is an enzyme that catalyzes the chemical reaction albendazole + ... H2O The four substrates of this enzyme are albendazole, NADPH, H+, and O2, whereas its three products are albendazole S-oxide, ... Other names in common use include albendazole oxidase, and albendazole sulfoxidase. It employs one cofactor, FAD. "Showing ... Enzyme 1.14.13.32 at KEGG Fargetton X, Galtier P, Delatour P (1986). "Sulfoxidation of albendazole by a cytochrome P450- ...
Tubulin
September 2012). "A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia". PLOS ... "Albendazole". Drugs.com. The American Society of Health-System Pharmacists. Archived from the original on September 23, 2015. ... The anti-worm drugs mebendazole and albendazole as well as the anti-gout agent colchicine bind to tubulin and inhibit ... While mebendazole still retains some binding affinity to human and Drosophila β-tubulin, albendazole almost exclusively binds ...
Coenurosis in humans
Albendazole works by binding to β- tubulin sites and inhibiting their polymerization into microtubules. This decreases the ... Firth, Mary (1984). Albendazole in helminthiasis. Royal Society of Medicine. ISBN 978-0-19-922001-4. OCLC 10207175. Tsurufuji, ... Praziquantel, Niclosamide, and Albendazole are the anthelminthics that are commonly used to treat coenurosis. Praziquantel ...
Microsporidiosis
Another agent used is albendazole. Because of its severe mortality risk in immunocompromised individuals, two main agents are ... used: Albendazole, which inhibits tubulin, and Fumagillin, which inhibits methionine aminopeptidase type two. "Microsporidiosis ...
Pediatric gynaecology
Pinworms are treated with albendazole. Vulvar Candida infections are uncommon in children, and generally occur in infants after ...
Vulvitis
Pinworms are treated with albendazole. Vulvar Candida infections are uncommon in children, and generally occur in infants after ...
Trichostrongylus
Alternative agents include mebendazole and albendazole. Successful treatment with ivermectin has also been reported. Another ...
Gongylonema ingluvicola
Albendazole is a common drug treatment. Sullivan, John (2011). A Color Atlas of Parasitology. pp. 150-151. ISBN 0-9665807-7-X. ...
Antimicrobial
Antiparasitic medications include metronidazole, iodoquinol and albendazole. Like all therapeutic antimicrobials, they must ...
Diphyllobothriasis
Other Reportedly, albendazole can also be effective. Gastrografin may be potentially used both as a diagnostic and therapeutic ... Molodozhnikova NM, Volodin AV, Bakulina NG (Nov-Dec 1991). "[The action of albendazole on the broad tapeworm]". Meditsinskaia ...
Opisthorchiasis
Albendazole can be used as an alternative. A randomized controlled trial published in 2011 showed that tribendimidine, a broad- ...
Filariasis
In a study from India, it was shown that a formulation of albendazole had better anti-filarial efficacy than albendazole itself ... There is good evidence that albendazole alone; or addition of albendazole to diethylcarbamazine or ivermectin, makes minimal ... A combination of diethylcarbamazine and albendazole is also effective. Side effects of the drugs include nausea, vomiting, and ... Macfarlane CL, Budhathoki SS, Johnson S, Richardson M, Garner P (January 2019). "Albendazole alone or in combination with ...
Strongyloides stercoralis
Albendazole is also effective in treating strongyloidiasis. Mebendazole has a much higher failure rate in clinical practice ... Hence, repeat treatments with ivermectin or albendazole must be administered to kill newly matured parasites that have ... than albendazole or ivermectin. However, these drugs have little effect on the autoinfective larvae. ...
Anisakis
... although treatment with albendazole alone (avoiding surgery) has been reported to be successful. Intestinal perforation (an ... "Albendazole for the Treatment of Anisakiasis Ileus". Clinical Infectious Diseases. 41 (12): 1825-1826. doi:10.1086/498309. PMID ...
Setaria cervi
Albendazole is very effective on the microfilariae. Hetrazan, tetramisole and levamisole are most commonly used. Anderson, R.C ... Nayak, A.; Gayen, P.; Saini, P.; Maitra, S.; Sinha Babu, S.P. (2011). "Albendazole induces apoptosis in adults and ...
Haycocknema perplexum
cite journal}}: Cite journal requires ,journal= (help) "Albendazole". PubChem. Haycocknema perplexum: [Internet]. ... 2018 [cited 26 March 2018]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/albendazole#section=Top v t e v t e (CS1 ... pdf Albendazole [Internet]. Pubchem.ncbi.nlm.nih.gov. ...
Ivermectin
... diethylcarbamazine citrate and albendazole in places without onchocerciasis; and ivermectin and albendazole in places with ... The U.S. Centers for Disease Control and Prevention (CDC) recommends ivermectin, albendazole, or mebendazole as treatments for ... Ivermectin is sometimes added to albendazole or mebendazole for whipworm treatment, and is considered a second-line treatment ... while the textbook Parasitic Diseases recommends albendazole or mebendazole. A 2020 Cochrane review concluded that the three ...
Bertiella (tapeworm)
Albendazole is not effective in treating this condition; praziquantel is the preferred agent. "Genus Bertiella Stiles & Hassall ...
Mansonella perstans
Single doses of albendazole alone have been consistently reported to have little or no effect on M. perstans microfilaremias in ... A 2009 study in Uganda evaluated the effects of ivermectin, albendazole, and a combined regimen of both drugs on M. perstans ... Combination treatments consisting of DEC plus mebendazole, or ivermectin and albendazole, have been shown to result in a highly ... Another study evaluated the effectiveness of ivermectin and albendazole in M. perstans and Wuchereria bancrofti coinfection in ...
Echinococcus multilocularis
Since it is difficult and not always possible to remove the entire parasite, medicine such as Albendazole is utilized to keep ... Currently, benzimidazoles (such as albendazole) are used to treat AE: only halt their proliferation and do not actually kill ... causes damage to germinal layer but does not kill parasite in vivo Treatment with a combination of albendazole/2-ME2 showed ... Albendazole and Mebendazole- what else?". Parasite. 21. 70. doi:10.1051/parasite/2014073. PMC 4271654. PMID 25526545. Massolo, ...
Pinworm infection
The benzimidazole compounds albendazole (brand names e.g., Albenza, Eskazole, Zentel and Andazol) and mebendazole (brand names ... The available data on mebendazole, albendazole, and pyrantel pamoate use in pregnancy is limited and they are all assigned to ... There is limited data on the use of pyrantel pamoate and albendazole in breastfeeding but WHO also classifies them as ... Treatment is typically with two doses of the medications mebendazole, pyrantel pamoate, or albendazole two weeks apart. ...
Gnathostoma spinigerum
The effective dosage at which albendazole has been shown effective is 90 mg/kg twice a day for 21 straight days. On the other ... Laboratory testing on mice treated once or twice daily with albendazole were shown to have a significant reduction in worm ... Maleewong W, Loahabhan P, Wongkham C, Intapan P, Morakote N, Khamboonruang C (1992). "Effects of albendazole on Gnathostoma ...
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PMID 7944574.{{cite journal}}: CS1 maint: multiple names: authors list (link) Sihota R, Honavar SG (1994). "Oral albendazole in ...
Refugee health
The US Protocol includes a single dose of albendazole. In many states, the domestic health screening exam recommends that all ... Swanson SJ, Phares CR, Mamo B, Smith KE, Cetron MS, Stauffer WM (April 2012). "Albendazole therapy and enteric parasites in ... As a preventative measure, refugees are administered, when available, albendazole and ivermectin prior to their asylum seeking ...
Angiostrongylus cantonensis
May 2007). "Albendazole therapy for eosinophilic meningitis caused by Angiostrongylus cantonensis". Parasitology Research. 100 ... Although combination therapy using albendazole and prednisolone has no significant advantage compared to treatment using ... such as thiobendazole or albendazole effective in improving the clinical course of the illness, a number of recent studies from ... "Treatment of eosinophilic meningitis with a combination of albendazole and corticosteroid" (PDF). The Southeast Asian Journal ...
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Single-dose albendazole (400 mg) is also very efficacious (>95%).[citation needed] A three-day course of nitazoxanide is 75-93 ... albendazole and praziquantel in the treatment of ascariasis, trichuriasis, and hymenolepiasis in children from Peru". Trans R ...
Taenia asiatica
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Albendazole: MedlinePlus Drug Information
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- Ivermectin works by binding to muscle and nerve cells of worms causing their paralysis and death.Albenza (albendazole) is effective for treating tapeworm infections, but may cause serious liver, blood, and eye problems Community members, ineligible for ivermectin, were treated with mebendazole, albendazole or deltamethrin to achieve a high level of coverage. (davidmichaelharding.com)
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Tablets12
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- Pharma major Lupin Limited (Lupin) announced that it has received approval for its Albendazole Tablets USP, 200 mg, from the United States Food and Drug Administration (U.S. FDA), to market a generic equivalent of Albenza ® Tablets, 200 mg, of Impax Laboratories Inc. (lupin.com)
- Albendazole Tablets USP (RLD: Albenza ® ) had an annual sales of approximately USD 34 million in the U.S. (IQVIA MAT April 2020). (lupin.com)
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Diethylcarbamazine3
- Three drugs are currently used to treat loiasis: diethylcarbamazine, ivermectin, and albendazole ( 4 ). (cdc.gov)
- Filariasis has been treated with the anthelmintic agents diethylcarbamazine and albendazole. (medscape.com)
- This article is a compilation of summaries prepared by lead investigators for large-scale safety and efficacy studies on mass drug administration of IDA (ivermectin, diethylcarbamazine, and albendazole) for lymphatic filariasis. (cdc.gov)
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Benzimidazole4
- Experimental evidence is available to benzimidazole carbamates and show a broad spec- show that albendazole not only kills the adult stages trum of activity against helminth parasites. (cdc.gov)
- Albendazole is a benzimidazole broad-spectrum anthelmintic, used for the treatment of variety of parasitic worm infestations. (pharmaffiliates.com)
- Albendazole is a benzimidazole anthelmintic used to destroy parasitic worms in ruminants but residues must not occur above maximum limits in food owing to reported human teratogenicity. (lgcgroup.com)
- Albendazole is a benzimidazole carbamate drug that inhibits tubulin polymerization, resulting in degeneration of cytoplasmic microtubules. (medscape.com)
Sulfoxide6
- Based on LC-MS-MS data, the two metabolites were predicted to be albendazole sulfoxide (M1) and albendazole sulfone (M2), the major mammalian metabolites reported previously. (who.int)
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- It is converted in the liver to its primary metabolite, albendazole sulfoxide. (medscape.com)
Lymphatic filariasis2
- Article on a symposium held to commemorate the 10th anniversary of the donation of Mectizan® and albendazole for the elimination of lymphatic filariasis. (mectizan.org)
- In addition, many deworming treatments are effectively provided through the administration of albendazole as part of treatment for lymphatic filariasis (LF), given the overlap in drugs between the two diseases. (evidenceaction.org)
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Efficacy4
- This comprehensive review briefly describes the history and pharmacology of albendazole as an anthelminthic drug and presents detailed summaries of the efficacy and safety of albendazole's use as an anthelminthic in humans. (cdc.gov)
- Because of the low incidence of hydatid disease, safety and efficacy of albendazole in patients with hydatid disease caused by E. granulosus were demonstrated by combining data from accumulated clinical reports in small series of patients. (soxanddawgs.com)
- Barda B, Ame M.S, Ali M.S, Albonico M, Puchkov M, Huwyler J, Hattendorf J, Keiser J. Efficacy and tolerability of moxidectin alone and in co-administration with albendazole plus oxantel pamoate against Trichuris trichiura infections: a randomised, non inferority, single-blind trial. (swisstph.ch)
- A cluster-randomized, community-based safety study performed in Fiji, Haiti, India, Indonesia and Papua New Guinea tested the safety and efficacy of a new regimen of ivermectin, DEC and albendazole (IDA). (cdc.gov)
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Effects of albendazole1
- ABSTRACT We examined the therapeutic effects of albendazole compared to metronidazole in 120 patients with giardiasis in Hamdan. (who.int)
Administration of albendazole1
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Loiasis3
- Trials in loiasis-endemic countries showed that short courses of albendazole had little effect on L. loa infection ( 6 , 7 ), but longer treatments (200 mg 2×/d for 21 d) resulted in decreased microfilaremia, blood eosinophil levels, and antifilarial antibodies ( 8 ). (cdc.gov)
- We describe the outcomes of 16 cases of imported loiasis in Italy with high-dose albendazole for 28 days and a single dose of ivermectin. (cdc.gov)
- We reviewed the medical records of patients with loiasis admitted to IRCCS Sacro Cuore Don Calabria Hospital (Negrar di Valpolicella, Italy) during 1993-2016 who had been treated with albendazole (400 mg 2×/d for 28 days), followed by ivermectin, (200 µg/kg, in single or multiple doses). (cdc.gov)
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- If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of albendazole bolus or bleeding: If you can, avoid people with infections. (soxanddawgs.com)
- c Conditions of use - 1 Horses albendazole bolus i Amount. (soxanddawgs.com)
- However, pretreatment filaremia was https://soxanddawgs.com/albendazole-bolus-1977729/albendazole-plus albendazole injection and L. loa microfilariae were not detectable in the cerebral spinal fluid. (soxanddawgs.com)
- general dosage: 1 bolus per 40Kg bodyweight (or 7.5mg albendazole per kg bodyweight). (amedicinecherry.com)
- For the treatment of mature fluke infection , the dose must be one bolus per 30Kg bodyweight (or 10mg albendazole per Kg bodyweight). (amedicinecherry.com)
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Indications1
- ii Indications albendazole injection use. (soxanddawgs.com)
Stable isotopes2
- Reference standards of Albendazole API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below. (pharmaffiliates.com)
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Anthelmintic drug1
- Screening scale studies were performed to biotransform anthelmintic drug albendazole by using twelve bacterial strains representing six genera and five actinomycetes cultures. (who.int)
Tablet1
- Albendazole comes as a tablet to take by mouth. (medlineplus.gov)
Apotheke Cialis1
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Dosage10
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- Your price for albendazole may be different depending on your dosage, how long you need to take the drug, and if you have insurance. (healthline.com)
- For specifics about how much the albendazole dosage your doctor recommends for you may cost, talk with your doctor or pharmacist. (healthline.com)
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Medicines3
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- Some medicines may interact with Albendazole. (grinh.com)
- Ask your health care provider if Albendazole may interact with other medicines that you take. (grinh.com)
Dose4
- You should not become pregnant while you are taking albendazole and for 3 days after your final dose. (medlineplus.gov)
- 20,000/mL and were treated with high-dose albendazole for 28 days and a single dose of ivermectin. (cdc.gov)
- In 2018, a patient with high microfilaremia was reported to be clear of infection after four 21-day courses of albendazole at a dose of 400 mg daily, followed by a single 150 µg/kg dose of ivermectin ( 9 ). (cdc.gov)
- If you miss a dose of Albendazole, take it as soon as possible. (grinh.com)
Infection6
- If you stop taking albendazole too soon or skip doses, your infection may not be completely treated. (medlineplus.gov)
- Although the sidered to be virtually identical (conspecific) in the detailed mechanisms of action are unclear, exper- past, such as Ascaris lumbricoides of humans and A . imental evidence from exposure of intestinal hel- suum of pigs, have recently been shown to be distinct, minths of several different species to albendazole without cross infection under natural conditions. (cdc.gov)
- If you have a certain type of parasitic infection , your doctor may suggest treatment with albendazole (Albenza). (healthline.com)
- A 55-year-old woman from Cameroon took oral albendazole 200 mg bd for a symptomatic L. loa infection with microfilaremia albendazole injection 152 microfilariae/ml and a Albendazole injection perstans infection of 133 microfilariae/ml. (soxanddawgs.com)
- Albendazole may rarely lower the ability of your body to fight infection. (grinh.com)
- In July 2015, the Philippines conducted a school-based mass drug administration using albendazole for soil-transmitted helminths infection. (who.int)
Allergic1
- you are allergic to any ingredient in Albendazole or to benzimidazoles (eg, rabeprazole). (grinh.com)
Veterinary2
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- When the corned beef was sampled at import the Public Analyst certified against the consignment because of an excess of residues of the veterinary medicine albendazole. (lgcgroup.com)
Support 241
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Generic15
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Parasitic worm2
- Albendazole is used to treat parasitic worm infections of the intestines and some other organs. (chemistonline.in)
- ALBENDAZOLE ORAL, also known as albendazolum, is a medication used for the treatment of a variety of parasitic worm infestations. (firsthorsevetcare.com)
Drugs7
- Albendazole has an average rating of 8.5 out of 10 from a total of 8 ratings on Drugs.com. (drugs.com)
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- Many drugs, including metronidazole and albendazole, are used for the treatment of the disease. (who.int)
- For the treatment of giardiasis, metronidazole is the drug of choice [7] but in cases of resistance, drugs such albendazole have been said to be effective [1]. (who.int)
- Review of the literature shows that there have been few clinical trials to compare albendazole with other effective anti-giardial drugs [2,4,8]. (who.int)
- Cialis works faster than other ED drugs and lasts for an albendazole emedicine . (uttmuhendislik.com)
Pills1
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Antiparasitic1
- Abd Plus Syp is a combination of Albendazole and Ivermectin, an antiparasitic medicine. (pharmeasy.in)
Giardiasis2
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Medication1
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Metabolite2
- Among the cultures studied, Bacillus subtilis MTCC 619, Escherichia coli MTCC 118 and Klebsiella pneumoniae MTCC 109 could transform albendazole to one metabolite whereas, Enterobacter aerogenes NCIM 2695, Klebsiella aerogenes NCIM 2258, Pseudomonas aeruginosa NCIM 2074 and Streptomyces griseus NCIM 2622 could transform albendazole into two metabolites in significant quantities. (who.int)
- Labeled metabolite of Albendazole, intended for use as an internal standard for the quantification of Albendazole by GC- or LC-mass spectrometry. (clearsynth.com)
Hypersensitivity1
- Albendazole shouldn't be administered if any hypersensitivity is discovered. (advacarepharma.com)
Strongyloidiasis1
- Chanthavanich P, Nontasut P, Prarinyanuparp V, Sa-Nguankiat S. Repeated doses of albendazole against strongyloidiasis in Thai children. (who.int)
Drug4
- Is albendazole available as a brand-name drug? (healthline.com)
- Optimal cysticidal effect of albendazole is achieved preoperatively or postoperatively when the drug is administered in three 28-day albenza medicine of therapy. (soxanddawgs.com)
- Michael Walker, the lead author, said, "Based on the findings of all the laboratories involved the definition of albendazole residues should be reconsidered to include the parent drug as well as its metabolites. (lgcgroup.com)
- Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma progression. (bvsalud.org)
Pregnancy3
- You should not begin your treatment with albendazole until you have taken a pregnancy test with negative results. (medlineplus.gov)
- If you are a woman who may become pregnant, you should have a negative pregnancy test before you start taking Albendazole. (grinh.com)
- Pregnancy and breast-feeding: Do not use Albendazole if you are pregnant. (grinh.com)
20201
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Farmacia9
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Doctor or pharmacist4
- For more details on albendazole, talk with your doctor or pharmacist. (healthline.com)
- For more information about the price of albendazole, talk with your doctor or pharmacist. (healthline.com)
- If you have questions about how you can pay for albendazole, you may also want to talk with your doctor or pharmacist. (healthline.com)
- If you still have questions about the price of albendazole, talk with your doctor or pharmacist. (healthline.com)
Metronidazole3
- Patients were randomized to receive albendazole (400 mg, once daily for 5 days) or metronidazole (250 mg, 3 times a day for 5 days). (who.int)
- Patients in the albendazole group had fewer side-effects while 43.3% of the metronidazole group experienced a metallic taste and 35.0% experienced loss of appetite. (who.int)
- As albendazole is an available and safe antiprotozoal medicine in the Islamic Republic of Iran and perhaps in other parts of the world, we conducted a clinical trial in order to assess the anti-giardial effects compared to metronidazole. (who.int)
Enrofloxacin1
- Two extraction strategies for albendazole, chloramphenicol, trimethoprim, enrofloxacin, oxitetracycline and nicarbazin in egg were optimized for its quantitation by liquid chromatography. (usda.gov)
20171
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Microfilaremia1
- If the microfilarial density is between 8000 and 30,000 mf/mL, ivermectin or albendazole should be used to reduce microfilaremia to less than 2000 mf/mL for DEC treatment. (medscape.com)
Treatment8
- if you are taking albendazole to treat neurocysticercosis, your doctor will probably tell you to take certain medications to prevent damage to the nervous system during your treatment. (medlineplus.gov)
- The facts that albendazole is safe and easy to administer, both in treatment of individuals and in treatment of whole communities where it has been given by paramedical and nonmedical personnel, have enabled its use to improve general community health, including the improved nutrition and development of children. (cdc.gov)
- Albendazole was withdrawn and she recovered without any specific treatment within the next 16 hours. (soxanddawgs.com)
- The clinical presentation, the interval after starting treatment, the evolution of the episode, and the results of cerebral spinal fluid analysis and albendazole injection in this case were similar to those seen in cases of encephalopathy following treatment of L. (soxanddawgs.com)
- Albendazole in treatment of human cystic echinococcosis: 12 years of experience. (ajtmh.org)
- Albendazole as a potential treatment for human hydatidosis. (ajtmh.org)
- Patient with failure of albendazole and ivermectin treatment. (cdc.gov)
- In visceral toxocariasis, treatment is usually required and includes five days of albendazole. (cdc.gov)
Injection1
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Findings1
- The key findings in the report on global Albendazole market are focused on the changing global Albendazole market dynamics, substantial new opportunities, critical forces that are likely to contribute to the growth of global Albendazole market both in advanced and developing economies. (goerieblogs.com)
Infections caused1
- Albendazole is also sometimes used to treat infections caused by roundworms, hookworms, threadworm, whipworm, pinworm, flukes, and other parasites (a plant or animal that lives within another living organism to receive some benefit). (medlineplus.gov)