Dictionaries, MedicalAlanine Dehydrogenase: An NAD-dependent enzyme that catalyzes the reversible DEAMINATION of L-ALANINE to PYRUVATE and AMMONIA. The enzyme is needed for growth when ALANINE is the sole CARBON or NITROGEN source. It may also play a role in CELL WALL synthesis because L-ALANINE is an important constituent of the PEPTIDOGLYCAN layer.Dictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Amino Acid Oxidoreductases: A class of enzymes that catalyze oxidation-reduction reactions of amino acids.NAD: A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)PeptidoglycanAlanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.Cell Wall: The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents.Alanine Racemase: A pyridoxal-phosphate protein that reversibly catalyzes the conversion of L-alanine to D-alanine. EC 5.1.1.1.Ammonia: A colorless alkaline gas. It is formed in the body during decomposition of organic materials during a large number of metabolically important reactions. Note that the aqueous form of ammonia is referred to as AMMONIUM HYDROXIDE.Archaeoglobus fulgidus: A species of extremely thermophilic, sulfur-reducing archaea. It grows at a maximum temperature of 95 degrees C. in marine or deep-sea geothermal areas.Archaeoglobus: A genus of extremely thermophilic, sulfate-reducing archaea, in the family Archaeoglobaceae.Glycine Dehydrogenase: An oxidoreductase that catalyzes the oxidative DEAMINATION of GLYCINE to glyoxylate and AMMONIA in the presence of NAD. In BACTERIA lacking transaminating pathways the enzyme can act in the reverse direction to synthesize glycine from glyoxylate and ammonia and NADH.Archaeal Proteins: Proteins found in any species of archaeon.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.D-Amino-Acid Oxidase4-Aminobutyrate Transaminase: An enzyme that converts brain gamma-aminobutyric acid (GAMMA-AMINOBUTYRIC ACID) into succinate semialdehyde, which can be converted to succinic acid and enter the citric acid cycle. It also acts on beta-alanine. EC 2.6.1.19.D-Alanine Transaminase: A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the reversible transfer of an amino group between D-Alanine and alpha-ketoglutarate to form PYRUVATE and D-GLUTAMATE, respectively. It plays a role in the synthesis of the bacterial CELL WALL. This enzyme was formerly classified as EC 2.6.1.10.Rhodotorula: A red yeast-like mitosporic fungal genus generally regarded as nonpathogenic. It is cultured from numerous sources in human patients.Stereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Deamination: The removal of an amino group (NH2) from a chemical compound.Substrate Specificity: A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.Ethionine: 2-Amino-4-(ethylthio)butyric acid. An antimetabolite and methionine antagonist that interferes with amino acid incorporation into proteins and with cellular ATP utilization. It also produces liver neoplasms.3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide): A ketone oxidoreductase that catalyzes the overall conversion of alpha-keto acids to ACYL-CoA and CO2. The enzyme requires THIAMINE DIPHOSPHATE as a cofactor. Defects in genes that code for subunits of the enzyme are a cause of MAPLE SYRUP URINE DISEASE. The enzyme was formerly classified as EC 1.2.4.3.ArchivesBiological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Serial Publications: Publications in any medium issued in successive parts bearing numerical or chronological designations and intended to be continued indefinitely. (ALA Glossary of Library and Information Science, 1983, p203)Publications: Copies of a work or document distributed to the public by sale, rental, lease, or lending. (From ALA Glossary of Library and Information Science, 1983, p181)Racemases and Epimerases: Enzymes that catalyze inversion of the configuration around an asymmetric carbon in a substrate having one (racemase) or more (epimerase) center(s) of asymmetry. (Dorland, 28th ed) EC 5.1.Phycobilisomes: Light energy harvesting structures attached to the THYLAKOID MEMBRANES of CYANOBACTERIA and RED ALGAE. These multiprotein complexes contain pigments (PHYCOBILIPROTEINS) that transfer light energy to chlorophyll a.Phycobiliproteins: Light harvesting proteins found in phycobilisomes.Phycocyanin: The metal-free blue phycobilin pigment in a conjugated chromoprotein of blue-green algae. It functions as light-absorbing substance together with chlorophylls.Cyanobacteria: A phylum of oxygenic photosynthetic bacteria comprised of unicellular to multicellular bacteria possessing CHLOROPHYLL a and carrying out oxygenic PHOTOSYNTHESIS. Cyanobacteria are the only known organisms capable of fixing both CARBON DIOXIDE (in the presence of light) and NITROGEN. Cell morphology can include nitrogen-fixing heterocysts and/or resting cells called akinetes. Formerly called blue-green algae, cyanobacteria were traditionally treated as ALGAE.Phycoerythrin: The metal-free red phycobilin pigment in a conjugated chromoprotein of red algae. It functions as a light-absorbing substance together with chlorophylls.Electric Power Supplies: Devices that control the supply of electric current for running electrical equipment.Bioelectric Energy Sources: Electric power supply devices which convert biological energy, such as chemical energy of metabolism or mechanical energy of periodic movements, into electrical energy.Rhodophyta: Plants of the division Rhodophyta, commonly known as red algae, in which the red pigment (PHYCOERYTHRIN) predominates. However, if this pigment is destroyed, the algae can appear purple, brown, green, or yellow. Two important substances found in the cell walls of red algae are AGAR and CARRAGEENAN. Some rhodophyta are notable SEAWEED (macroalgae).Pigments, Biological: Any normal or abnormal coloring matter in PLANTS; ANIMALS or micro-organisms.Light-Harvesting Protein Complexes: Complexes containing CHLOROPHYLL and other photosensitive molecules. They serve to capture energy in the form of PHOTONS and are generally found as components of the PHOTOSYSTEM I PROTEIN COMPLEX or the PHOTOSYSTEM II PROTEIN COMPLEX.Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Sequence Analysis, Protein: A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.Systems Integration: The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Proteome: The protein complement of an organism coded for by its genome.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.NADP Transhydrogenases: Enzymes that catalyze the reversible reduction of NAD by NADPH to yield NADP and NADH. This reaction permits the utilization of the reducing properties of NADPH by the respiratory chain and in the reverse direction it allows the reduction of NADP for biosynthetic purposes.Amination: The creation of an amine. It can be produced by the addition of an amino group to an organic compound or reduction of a nitro group.NADP: Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)NADH, NADPH Oxidoreductases: A group of oxidoreductases that act on NADH or NADPH. In general, enzymes using NADH or NADPH to reduce a substrate are classified according to the reverse reaction, in which NAD+ or NADP+ is formally regarded as an acceptor. This subclass includes only those enzymes in which some other redox carrier is the acceptor. (Enzyme Nomenclature, 1992, p100) EC 1.6.Hydromorphone: An opioid analgesic made from MORPHINE and used mainly as an analgesic. It has a shorter duration of action than morphine.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.

Cold-adapted alanine dehydrogenases from two antarctic bacterial strains: gene cloning, protein characterization, and comparison with mesophilic and thermophilic counterparts. (1/60)

The genes encoding NAD(+)-dependent alanine dehydrogenases (AlaDHs) (EC 1.4.1.1) from the Antarctic bacterial organisms Shewanella sp. strain Ac10 (SheAlaDH) and Carnobacterium sp. strain St2 (CarAlaDH) were cloned and expressed in Escherichia coli. Of all of the AlaDHs that have been sequenced, SheAlaDH exhibited the highest level of sequence similarity to the AlaDH from the gram-negative bacterium Vibrio proteolyticus (VprAlaDH). CarAlaDH was most similar to AlaDHs from mesophilic and thermophilic Bacillus strains. SheAlaDH and CarAlaDH had features typical of cold-adapted enzymes; both the optimal temperature for catalytic activity and the temperature limit for retaining thermostability were lower than the values obtained for the mesophilic counterparts. The k(cat)/K(m) value for the SheAlaDH reaction was about three times higher than the k(cat)/K(m) value for VprAlaDH, but it was much lower than the k(cat)/K(m) value for the AlaDH from Bacillus subtilis. Homology-based structural models of various AlaDHs, including the two psychotropic AlaDHs, were constructed. The thermal instability of SheAlaDH and CarAlaDH may result from relatively low numbers of salt bridges in these proteins.  (+info)

Properties of the 40 kDa antigen of Mycobacterium tuberculosis, a functional L-alanine dehydrogenase. (2/60)

The 40 kDa antigen of Mycobacterium tuberculosis is the first antigen reported to be present in the pathogenic M. tuberculosis, but not in the vaccine strain Mycobacterium bovis BCG. It is a functional L-alanine dehydrogenase (EC 1.4.1.1) and hence one of the few antigens possessing an enzymic activity. This makes the 40 kDa antigen attractive for potential diagnostic and therapeutic interventions. Recently, we developed a strategy to purify quantities of the recombinant protein in active form, and here we describe the biochemical properties of this enzyme. In the oxidative-deamination reaction, the enzyme showed K(m) values of 13. 8 mM and 0.31 mM for L-alanine and NAD(+), respectively, in a random-ordered mechanism. K(m, app) values in the reductive-amination reaction are 35.4 mM, 1.45 mM and 98.2 microM for ammonium, pyruvate and NADH, respectively. The enzyme is highly specific for all of its substrates in both directions. The pH profile indicates that oxidative deamination virtually may not occur at physiological pH. Hence L-alanine most likely is the product of the reaction catalysed in vivo. The enzyme is heat-stable, losing practically no activity at 60 degrees C for several hours.  (+info)

Structure and mechanism of proton-translocating transhydrogenase. (3/60)

Recent developments have led to advances in our understanding of the structure and mechanism of action of proton-translocating (or AB) transhydrogenase. There is (a) a high-resolution crystal structure, and an NMR structure, of the NADP(H)-binding component (dIII), (b) a homology-based model of the NAD(H)-binding component (dI) and (c) an emerging consensus on the position of the transmembrane helices (in dII). The crystal structure of dIII, in particular, provides new insights into the mechanism by which the energy released in proton translocation across the membrane is coupled to changes in the binding affinities of NADP(+) and NADPH that drive the chemical reaction.  (+info)

Disruption of aldA influences the developmental process in Myxococcus xanthus. (4/60)

Previously, we identified a gene (aldA) from Myxococcus xanthus, which we suggested encoded the enzyme alanine dehydrogenase on the basis of similarity to known Ald protein sequences (M. J. Ward, H. Lew, A. Treuner-Lange, and D. R. Zusman, J. Bacteriol. 180:5668-5675, 1998). In this study, we have confirmed that aldA does encode a functional alanine dehydrogenase, since it catalyzes the reversible conversion of alanine to pyruvate and ammonia. Whereas an aldA gene disruption mutation did not significantly influence the rate of growth or spreading on a rich medium, AldA was required for growth on a minimal medium containing L-alanine as the major source of carbon. Under developmental conditions, the aldA mutation caused delayed aggregation in both wild-type (DZ2) and FB (DZF1) strains. Poorly formed aggregates and reduced levels of spores were apparent in the DZ2 aldA mutant, even after prolonged development.  (+info)

Protein-coding genes as molecular markers for ecologically distinct populations: the case of two Bacillus species. (5/60)

Bacillus globisporus and Bacillus psychrophilus are one among many pairs of ecologically distinct taxa that are distinguished by very few nucleotide differences in 16S rRNA gene sequence. This study has investigated whether the lack of divergence in 16S rRNA between such species stems from the unusually slow rate of evolution of this molecule, or whether other factors might be preventing neutral sequence divergence at 16S rRNA as well as every other gene. B. globisporus and B. psychrophilus were each surveyed for restriction-site variation in two protein-coding genes. These species were easily distinguished as separate DNA sequence clusters for each gene. The limited ability of 16S rRNA to distinguish these species is therefore a consequence of the extremely slow rate of 16S rRNA evolution. The present results, and previous results involving two Mycobacterium species, demonstrate that there exist closely related species which have diverged long enough to have formed clearly separate sequence clusters for protein-coding genes, but not for 16S rRNA. These results support an earlier argument that sequence clustering in protein-coding genes could be a primary criterion for discovering and identifying ecologically distinct groups, and classifying them as separate species.  (+info)

Reassessment of major products of N2 fixation by bacteroids from soybean root nodules. (6/60)

NH3/ was the principal product from soybean bacteroids, prepared by various procedures, when assayed in solution in a flow chamber under N2 fixation conditions. In addition, small quantities of alanine were produced (reaching 20% of NH3/ under some conditions). Some 15N was assimilated by bacteroids purified from soybean root nodules on Percoll density gradients and shaken with 15N2 and 0.008 atm O2. Under these conditions, accounted for 93% of the (15)N fixed into the soluble fraction. This fraction contained no measurable [15N]alanine. Neither these bacteroids nor those prepared by the previously used differential centrifugation method, when incubated with exogenous alanine under non-N2-fixing conditions, gave rise to NH3 from alanine. Therefore, contamination of bacteroid preparations with enzymes of plant cytosolic origin and capable of producing NH3 from alanine cannot explain the failure to detect [15N]alanine [as reported elsewhere: Waters, J. K., Hughes, B. L., II, Purcell, L. C., Gerhardt, K. O., Mawhinney, T. P. & Emerich, D. W. (1998). Proc Natl Acad Sci USA 95, 12038-12042]. Cell-free extracts of the bacteroids as used in the 15N experiments contained alanine dehydrogenase and were able to produce alanine from pyruvate and. Other experiments with alanine dehydrogenase in extracts of cultured rhizobia and bacteroids are reported and discussed in relation to the 15N experiments. Possible reasons for the differences between laboratories regarding the role of alanine are discussed. It is concluded that NH3 is the principal soluble product of N2 fixation by suspensions of soybean bacteroids ex planta and that should continue to be considered the principal product of N2 fixation which is assimilated in vivo in soybean nodules.  (+info)

Hypoxic response of Mycobacterium tuberculosis studied by metabolic labeling and proteome analysis of cellular and extracellular proteins. (7/60)

The events involved in the establishment of a latent infection with Mycobacterium tuberculosis are not fully understood, but hypoxic conditions are generally believed to be the environment encountered by the pathogen in the central part of the granuloma. The present study was undertaken to provide insight into M. tuberculosis protein expression in in vitro latency models where oxygen is depleted. The response of M. tuberculosis to low-oxygen conditions was investigated in both cellular and extracellular proteins by metabolic labeling, two-dimensional electrophoresis, and protein signature peptide analysis by liquid chromatography-mass spectrometry. By peptide mass fingerprinting and immunodetection, five proteins more abundant under low-oxygen conditions were identified from several lysates of M. tuberculosis: Rv0569, Rv2031c (HspX), Rv2623, Rv2626c, and Rv3841 (BfrB). In M. tuberculosis culture filtrates, two additional proteins, Rv0363c (Fba) and Rv2780 (Ald), were found in increased amounts under oxygen limitation. These results extend our understanding of the hypoxic response in M. tuberculosis and potentially provide important insights into the physiology of the latent bacilli.  (+info)

Mycobacterium smegmatis L-alanine dehydrogenase (Ald) is required for proficient utilization of alanine as a sole nitrogen source and sustained anaerobic growth. (8/60)

NAD(H)-dependent L-alanine dehydrogenase (EC 1.4.1.1) (Ald) catalyzes the oxidative deamination of L-alanine and the reductive amination of pyruvate. To assess the physiological role of Ald in Mycobacterium smegmatis, we cloned the ald gene, identified its promoter, determined the protein expression levels, and analyzed the combined effects of nutrient supplementation, oxygen availability, and growth stage on enzyme activity. High Ald activities were observed in cells grown in the presence of L- or D-alanine regardless of the oxygen availability and growth stage. In exponentially growing cells under aerobic conditions, supplementation with alanine resulted in a 25- to 50-fold increase in the enzyme activity. In the absence of alanine supplementation, 23-fold-higher Ald activities were observed in cells grown exponentially under anaerobic conditions. Furthermore, M. smegmatis ald null mutants were constructed by targeted disruption and were shown to lack any detectable Ald activity. In contrast, the glycine dehydrogenase (EC 1.4.1.10) (Gdh) activity in mutant cells remained at wild-type levels, indicating that another enzyme protein is responsible for the physiologically relevant reductive amination of glyoxylate. The ald mutants grew poorly in minimal medium with L-alanine as the sole nitrogen source, reaching a saturation density 100-fold less than that of the wild-type strain. Likewise, mutants grew to a saturation density 10-fold less than that of the wild-type strain under anaerobic conditions. In summary, the phenotypes displayed by the M. smegmatis ald mutants suggest that Ald plays an important role in both alanine utilization and anaerobic growth.  (+info)

*Alanine dehydrogenase

L-alanine dehydrogenase, NAD+-linked alanine dehydrogenase, alpha-alanine dehydrogenase, NAD+-dependent alanine dehydrogenase, ... alanine oxidoreductase, and NADH-dependent alanine dehydrogenase. T Alanine dehydrogenase contains both a N-terminus and C- ... Alanine dehydrogenase (EC 1.4.1.1) is an enzyme that catalyzes the chemical reaction L-alanine + H2O + NAD+ ⇌ {\displaystyle \ ... O'Connor RJ, Halvorson H (March 1961). "The substrate specificity of L-alanine dehydrogenase". Biochimica et Biophysica Acta. ...

*Methylomonas scandinavica

This is confirmed by the presence of glutamine synthetase, glutamate synthase, and alanine dehydrogenase. Since M. scandinavica ... The TCA cycle is incomplete due to the inactivity of the α-ketoglutarate dehydrogenase enzyme. M. scandinavica also uses ...

*Strombine dehydrogenase

Dando PR (1981). "Strombine [N-(carboxymethyl)-D-alanine] dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine ... D-alanine]dehydrogenase, and N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase. ... In enzymology, a strombine dehydrogenase (EC 1.5.1.22) is an enzyme that catalyzes the chemical reaction N-(carboxymethyl)-D- ... The systematic name of this enzyme class is N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming). Other names in ...

*Alanopine dehydrogenase

Dando PR (1981). "Strombine [N-(carboxymethyl)-D-alanine] dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine] ... alanine]dehydrogenase, meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase, alanopine: NAD+ oxidoreductase, ADH, and alanopine: ... Alanopine dehydrogenase (EC 1.5.1.17) is an enzyme that catalyzes the chemical reaction 2,2'-iminodipropanoate + NAD+ + H2O ... Its 4 products are L-alanine, pyruvate, nicotinamide adenine dinucleotide, and hydrogen ion. This enzyme belongs to the family ...

*Pyruvic acid

Transamination by alanine transaminase produces alanine. Reduction by lactate dehydrogenase produces lactate. Pyruvate is sold ... It can also be used to construct the amino acid alanine and can be converted into ethanol or lactic acid via fermentation. ... Jaimes, R., III (Jul 2015). "Functional response of the isolated, perfused normoxic heart to pyruvate dehydrogenase activation ... Pyruvate from glycolysis is converted by fermentation to lactate using the enzyme lactate dehydrogenase and the coenzyme NADH ...

*Aldehyde dehydrogenase 6 family, member A1

Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and ... demonstration of defective valine and beta-alanine metabolism and reduced malonic semialdehyde dehydrogenase activity in ... "CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA ... "CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA ...

*Acquired non-inflammatory myopathy

... alanine aminotransferase, and lactate dehydrogenase are closely examined. Abnormal levels of these proteins are indicative of ... Muscle enzymes are increased, commonly lactate dehydrogenase (LDH). (HMG-CoA) reductase inhibitors are commonly used in the ...

*Malonate-semialdehyde dehydrogenase

This enzyme participates in beta-alanine metabolism. Nakamura K; Bernheim F (1961). "Studies on malonic semialdehyde ... In enzymology, a malonate-semialdehyde dehydrogenase (EC 1.2.1.15) is an enzyme that catalyzes the chemical reaction 3- ... dehydrogenase from Pseudomonas aeruginosa". Biochim. Biophys. Acta. 50: 147-152. doi:10.1016/0006-3002(61)91071-X. PMID ...

*Malonate-semialdehyde dehydrogenase (acetylating)

This enzyme participates in 4 metabolic pathways: inositol metabolism, alanine and aspartate metabolism, beta-alanine ... Hayaishi, O; Nishizuka, Y; Tatibana, M; Takeshita, M; Kuno, S (1961). "Enzymatic studies on the metabolism of beta-alanine". ... In enzymology, a malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) is an enzyme that catalyzes the chemical ...

*3-hydroxypropionate dehydrogenase

This enzyme participates in beta-alanine metabolism and propanoate metabolism. Den H, Robinson WG, Coon MJ (1959). "Enzymatic ... In enzymology, a 3-hydroxypropionate dehydrogenase (EC 1.1.1.59) is an enzyme that catalyzes the chemical reaction 3- ...

*Lactate dehydrogenase

Alanine and lactate are major gluconeogenic precursors that enter gluconeogenesis as pyruvate. The high NADH/NAD+ ratio shifts ... Lactate dehydrogenase-A deficiency is caused by a mutation to the LDHA gene, while lactate dehydrogenase-B deficiency is caused ... LDH is measured by the lactate dehydrogenase (LDH) test (also known as the LDH test or lactic acid dehydrogenase test). ... Ethanol is dehydrogenated to acetaldehyde by alcohol dehydrogenase, and further into acetic acid by acetaldehyde dehydrogenase ...

*Beta-Alanine

The malonate semialdehyde can then be converted into malonate via malonate-semialdehyde dehydrogenase. Malonate is then ... β-alanine > taurine ≫ alanine, L-serine > proline). There is evidence that β-alanine supplementation can increase exercise ... The IUPAC name for β-alanine is 3-aminopropanoic acid. Unlike its counterpart α-alanine, β-alanine has no stereocenter. In ... β-Alanine (or beta-alanine) is a naturally occurring beta amino acid, which is an amino acid in which the amino group is at the ...

*Dihydrolipoamide dehydrogenase

Kim H (2006). "Activity of human dihydrolipoamide dehydrogenase is largely reduced by mutation at isoleucine-51 to alanine". J ... "How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase ... "How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase ... Dihydrolipoamide dehydrogenase (DLD), also known as dihydrolipoyl dehydrogenase, mitochondrial, is an enzyme that in humans is ...

*Spermidine dehydrogenase

This enzyme participates in urea cycle and metabolism of amino groups and beta-alanine metabolism. It has 2 cofactors: FAD, and ... IIE2a Speridine dehydrogenase". Adv. Enzymol. Relat. Areas Mol. Biol. 36: 225-226. Molecular and Cellular Biology portal. ... In enzymology, a spermidine dehydrogenase (EC 1.5.99.6) is an enzyme that catalyzes the chemical reaction spermidine + acceptor ... "Identification of flavin adenine dinucleotide and heme in a homogeneous spermidine dehydrogenase from Serratia marcescens". J. ...

*Aminobutyraldehyde dehydrogenase

This enzyme participates in the urea cycle and the metabolism of amino groups and beta-alanine. Callewaert DM, Rosemblatt MS, ... ABAL dehydrogenase, 4-aminobutyraldehyde dehydrogenase, 4-aminobutanal dehydrogenase, gamma-aminobutyraldehyde dehydroganase, 1 ... In enzymology, an aminobutyraldehyde dehydrogenase (EC 1.2.1.19) is an enzyme that catalyzes the chemical reaction 4- ... Prieto MI, Martin J, Balana-Fouce R, Garrido-Pertierra A (1987). "Properties of gamma-aminobutyraldehyde dehydrogenase from ...

*Saliva

N-acetylmuramoyl-L-alanine amidase, NAD(P)H dehydrogenase (quinone), superoxide dismutase, glutathione transferase, class 3 ... aldehyde dehydrogenase, glucose-6-phosphate isomerase, and tissue kallikrein (function unknown) Cells: possibly as many as 8 ...

*Dihydrouracil dehydrogenase (NAD+)

... and dihydrouracil dehydrogenase (NAD+). This enzyme participates in 3 metabolic pathways: pyrimidine metabolism, beta-alanine ... Other names in common use include dehydrogenase, dihydrouracil, dihydropyrimidine dehydrogenase, dihydrothymine dehydrogenase, ... In enzymology, a dihydrouracil dehydrogenase (NAD+) (EC 1.3.1.1) is an enzyme that catalyzes the chemical reaction 5,6- ... Purification and properties of dihydrouracil dehydrogenase". J. Biol. Chem. 227 (2): 693-700. PMID 13462991. Molecular and ...

*Alanine

In the first step, α-ketoglutarate, ammonia and NADH are converted by glutamate dehydrogenase to glutamate, NAD+ and water. In ... "alanine scanning", where every position in turn is mutated to alanine. Alanine is a nonessential amino acid, meaning it can be ... forming alanine and α-ketoglutarate. The alanine enters the bloodstream, and is transported to the liver. The alanine ... Alanine is found in a wide variety of foods, but is particularly concentrated in meats. Alanine can be synthesized from ...

*Beta-alanopine dehydrogenase

The systematic name of this enzyme class is N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming). Sato ... Beta-alanopine dehydrogenase (EC 1.5.1.26) is an enzyme that catalyzes the chemical reaction beta-alanopine + NAD+ + H2O ⇌ {\ ... displaystyle \rightleftharpoons } beta-alanine + pyruvate + NADH + H+ The 3 substrates of this enzyme are beta-alanopine, ... nicotinamide adenine dinucleotide ion, and water, whereas its 4 products are beta-alanine, pyruvate, nicotinamide adenine ...

*Pyruvate dehydrogenase (acetyl-transferring)

... and pyruvic dehydrogenase. This enzyme participates in 5 metabolic pathways: glycolysis / gluconeogenesis, alanine and ... pyruvate dehydrogenase, pyruvate dehydrogenase (lipoamide), pyruvate dehydrogenase complex, pyruvate:lipoamide 2-oxidoreductase ... In enzymology, a pyruvate dehydrogenase (acetyl-transferring) (EC 1.2.4.1) is an enzyme that catalyzes the chemical reaction ... decarboxylating and, acceptor-acetylating), pyruvic acid dehydrogenase, ...

*List of MeSH codes (D08)

... alanine dehydrogenase MeSH D08.811.682.664.500.125 --- d-amino-acid oxidase MeSH D08.811.682.664.500.261 --- d-aspartate ... acyl-coa dehydrogenases MeSH D08.811.682.660.150.100 --- acyl-coa dehydrogenase MeSH D08.811.682.660.150.150 --- acyl-coa ... l-iditol 2-dehydrogenase MeSH D08.811.682.047.150.700.649 --- mannitol dehydrogenase MeSH D08.811.682.047.150.900 --- uridine ... beta-alanine-pyruvate transaminase MeSH D08.811.913.477.700.347 --- d-alanine transaminase MeSH D08.811.913.477.700.470 --- ...

*List of EC numbers (EC 1)

... alanine dehydrogenase EC 1.4.1.2: glutamate dehydrogenase EC 1.4.1.3: glutamate dehydrogenase (NAD(P)+) EC 1.4.1.4: glutamate ... EC 1.1.1.1: alcohol dehydrogenase EC 1.1.1.2: alcohol dehydrogenase (NADP+) EC 1.1.1.3: homoserine dehydrogenase EC 1.1.1.4: (R ... L-arabinitol 4-dehydrogenase EC 1.1.1.13: L-arabinitol 2-dehydrogenase EC 1.1.1.14: L-iditol 2-dehydrogenase EC 1.1.1.15: D- ... glutaryl-CoA dehydrogenase EC 1.3.8.7: medium-chain acyl-CoA dehydrogenase EC 1.3.8.8: long-chain acyl-CoA dehydrogenase EC 1.3 ...

*Glutamate-glutamine cycle

... then transaminated by alanine aminotransferase into lactate-derived pyruvate to form alanine, which is exported to astrocytes. ... The ammonia fixed as part of the glutamate dehydrogenase enzyme reaction in the neurons is transaminated into α-ketoisocaproate ... In the opposite direction of the amino acid, a corresponding molecule is transported; for alanine this molecule is lactate; for ... The ammonia produced in neurons is fixed into α-ketoglutarate by the glutamate-dehydrogenase reaction to form glutamate, ...

*Aldehyde dehydrogenase (NAD+)

... beta-alanine metabolism, glycerolipid metabolism, pyruvate metabolism, 1,2-dichloroethane degradation, propanoate metabolism, 3 ... NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked ... Other names in common use include CoA-independent aldehyde dehydrogenase, m-methylbenzaldehyde dehydrogenase, ... aldehyde dehydrogenase, propionaldehyde dehydrogenase, and aldehyde dehydrogenase (NAD). This enzyme participates in 17 ...

*Dihydropyrimidine dehydrogenase (NADP+)

... beta-alanine metabolism, and pantothenate and coa biosynthesis. As of late 2007, 5 structures have been solved for this class ... DHU dehydrogenase hydropyrimidine dehydrogenase dihydropyrimidine dehydrogenase (NADP+) This enzyme participates in 3 metabolic ... dihydrothymine dehydrogenase dihydrouracil dehydrogenase (NADP+) 4,5-dihydrothymine: oxidoreductase DPD DHPDH dehydrogenase, ... In enzymology, a dihydropyrimidine dehydrogenase (NADP+) (EC 1.3.1.2) is an enzyme that catalyzes the chemical reaction 5,6- ...

*WNT4

This causes an alanine to valine residue substitution at amino acid position 114, a location highly conserved in all organisms ... In addition, it removes the inhibition of steroidogenic enzymes like 3β-hydroxysteriod dehydrogenase and 17α-hydroxylase. ...
Alanine dehydrogenase catalyses the NAD-dependent reversible reductive amination of pyruvate into alanine. Pyridine nucleotide transhydrogenase catalyses the reduction of NADP+ to NADPH with the concomitant oxidation of NADH to NAD+. This enzyme is located in the plasma membrane of prokaryotes and in the inner membrane of the mitochondria of eukaryotes. The transhydrogenation between NADH and NADP is coupled with the translocation of a proton across the membrane. In prokaryotes the enzyme is composed of two different subunits, an alpha chain (gene pntA) and a beta chain (gene pntB), while in eukaryotes it is a single chain protein.. The sequence of alanine dehydrogenase from several bacterial species is related with that of the alpha subunit of bacterial pyridine nucleotide transhydrogenase and the N-terminal half of the eukaryotic enzyme. The two most conserved regions correspond respectively to the N-terminal domain of these proteins, and to a central glycine-rich region which is part of the ...
1OMO: Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and mammalian mu crystallin.
DNA barcode technology was a powerful tool for Microcystis identification. Acknowledgments This work was supported by The International Science & Technology Cooperation Program of China (Grant No. 2013DFA71340) and Major National Science & Technology Project of Water Pollution Control and Management of China (Grant No. 012ZX07203-002). References 1. An J, Carmichael WW (1994) Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins. Maniatis T, Fritsch EF, Sambrook J (1982) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor 11. Kuroda S, Tanizawa K, Sakamoto Y, Tanaka H, Soda K (1990) Alanine dehydrogenase from two Bacillus species with distinct thermo stabilities: molecular cloning, DNA and protein sequence determination, and structural comparison with other NAD (P)-dependent dehydrogenases. Biochemistry 29:1009-1015 12. Ohshima T, Nishida N, Bakthavatsalam S, ...
1OMO: Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and mammalian mu crystallin.
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
Adherencia al tratamiento en enfermedad cardiovascular: rediseño y validación de un instrumento / Adherence to treatment in cardiovascular disease: Re-design and validation of an instrument / Aderência ao tratamento em doença cardiovascular: Redesenho e validação de um instrumento
An NAD-dependent enzyme that catalyzes the reversible Deamination of L-Alanine to PYRUVATE and Ammonia. The enzyme is needed for Growth when Alanine is the sole Carbon or Nitrogen source. It may also play a Role in Cell Wall synthesis because L-Alanine is an important constituent of the PEPTIDOGLYCAN layer ...
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Marius Ader is the author of this article in the Journal of Visualized Experiments: Subretinal Transplantation of MACS Purified Photoreceptor Precursor Cells into the Adult Mouse Retina
semua jentera utk menghadapi banjir telah siap sedia dr segi mental & fizikal (sib baik pej. haku x termasuk dlm petugas banjir..selamat..) sama ada di peringkat daerah mahupun negeri... pusat pemindahan pun dh sedia agaknya.. ye la kan, dh macam acara tahunan... so x de la terkejut sgt... cuma thn ni x tau la bnjr besar ke kecik...harap2 xde la serius sgt & tidak melibatkan kemalangan jiwa... weh, apsal budak2 kat cni suka sgt mandi/terjun kat tali air pd musim banjir nih? ingat swimming pool hape... heran cikjah... kadang2 banjir kat cni mcm pesta air... siap ader yg bawak pukat nk tangkap ikan... yg bestnya, memang ader ikan pun kat tepi2 jalan tuh.. siap ader org jual2 air plak... hihihi... asalkan mereka & keluarga mereka bahagia cukup la ...
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Dr. Viviana Popescu PSIHONEUROIMUNOLOGIA CANCERULUI CADRUL GENERAL - TEORETIC Termenul de PNI a fost introdus in 1975 de dr. ROBERT ADER, profesor de medicina
Masa saya kecik2 dulu... biskut dam adalah biskut raya wajib yg mak akan buat, selain samperit, biskut kacang & kuih gunting... tp sejak anak2 dh keje, dh besar panjang, beranak pinak... mak pun dh pencen buat kuih raya... kononnyer nk rs air tgn anak2 pulak...tp hampeh... saya & kakak (sy hanya ader 2 beradik perempuan) masing2 keras tgn + kurang berminat utk buat biskut2 yg mengambil masa berjam2 utk disiapkan... lgpun klu buat 60% mungkin jd...yg selebihnyer.... terhangit la... rupa x cantik laa....at last buat mkn sndri je... (byknyer alasan ...
All content on this website is for informational purposes only and should not be considered to be a specific diagnosis or treatment plan for any individual situation. Use of this website and the information contained herein does not create a doctor-patient relationship. Always consult with your own doctor in connection with any questions or issues you may have regarding your own health or the health of others ...
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Alan Alda chats with Seth about the keys to communication from his book If I Understood You, Would I Have This Look On My Face? and explains why you shouldnt perform gibberish shows for drunken sailors. ...
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Hati tul2 rs sedih sgt... geram, sakit hati semua ader.... jenuh aku wat baik ngan org... bukan nk ungkit pa pe... tp tue ler sekadar nak ...
Hati tul2 rs sedih sgt... geram, sakit hati semua ader.... jenuh aku wat baik ngan org... bukan nk ungkit pa pe... tp tue ler sekadar nak ...
Tawan2... penah x tawan2 rs letih2...lenguh2 badan bila tita byk bermain... mcm caya yg macih menerap ni celalu je rs lenguh2 pd bdn caya... Kt cni caya ader sket tips utk tawan2 klu tita rs penat/letih semasa tgh bermain... cara2nyer :- (gambar utk rujukan supaya tawan2 lebih memahami ...
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Cláudia L. Farinha, Alda S. Baltar, Sandrina G. Nunes, Nuno F. Franqueira, João P. Figueira, Isabel A. Pires, Maria L. Cachulo, Rufino M. Silva Eur J Ophthalmol 2013; 23(6): 887 - 898 ...
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Resumo: Na indústria automobilística a principal função dos revestimentos é a proteção contra corrosão. O processo de fosfatização tem uso generalizado na indústria, pois forma uma película altamente aderente que proporciona alta proteção contra corrosão quando combinados com revestimentos orgânicos. Todavia, esse tem sido substituído, dado que não são amigáveis ambientalmente devido à energia gasta durante o processo e os metais utilizados. Exposto estes fatores, tornou-se necessário o desenvolvimento de novos revestimentos de conversão da superfície que tenham menor impacto sobre o meio ambiente e não comprometam o resultado de proteção contra corrosão. O óxido de zircônia é um novo e promissor prétratamento. Este tratamento é livre de fosfatos e metais nocivos ao meio ambiente e pode ser aplicado em temperatura ambiente. O oxido de zircônio demonstra boa aderência à superfície metálica. O objetivo deste trabalho foi validar a hipótese de que tanto o ...
[89 Pages Report] Check for Discount on Global and China L-Alanine Market Research by Company, Type & Application 2013-2025 report by HeyReport. Summary L-Alanine is a nonessential a-amino acid and...
While Alanine is considered a nonessential acid, meaning that it is produced naturally in the body, L-Alanine supplementation can be very important. This is a pure product that comes in powdered form.. ...
2.64G 0.74G 1.50G 6.41G 8G 154G 3.67G 0.81G 0.52G 2.24G 32G 2.21G 3.07G 2.21G 0.11G 2.64G 4.34G 2.83G 1.28G 2.21G 3.07G 3.07G 2.21G 3.48G 1.75G ...
ok, otak kiter pun ader switch off button....dipanggil reticular activating system RAS.......bila otak dah switch off badan, dia pun auto switch off RAS ni......so tinggal automatic function (degupan jantung, bernafas etc.) jer yang on.....kirenyer screensaver laaa or hibernate... so,, bila kita bangun, RAS switched on balik......kita sedar fully awake state....tapi kadang2, electrical signal tak diactivate kan oleh otak suh switch on balik badan kiter...... maka masa tu laa badan kita lumpuh seketika... before otak activate balik......mmg menakutkan tapi benar..... tapi paralysis tu tak semestinyer complete atau full..kadang2 partial atau sebahagian jer...tu ader yang boleh gerakkan ibu jari, tp badan lain lumpuh etc ...
Morning sickness might occur due to hormonal changes or stretching and distension of the uterus. Dam may appear a bit apathetic. She may be off her feed for a while and vomit from time to time. Feeding the dam several meals spaced throughout the day might help. Your veterinarian may want to prescribe a drug to relax the uterus. Alda is now very mellow and sleepy. Her response to seeing the Vet for the ultrasound was quiet and unexcited (not her usual self). She is eating well and seems hungry.. ...
SINOGEL Amino Acid Co., Ltd.(China) is located in Huaibei Economic Development Zone,Anhui,China.It is found in June,2008,the registered capital is US$4.65million.The main products are L-Alanine,DL-Alanine and L-Asparitic acid.
Kek butter cream hijau tu kek coklat kat dalam dia...sama lah macam cup cake tu..Hari tu teman akak kat office ni pergi kedai bahan2 kek..tetiba menjelma satu semangat dan aura yang bukan2 nak buat kek plak...Tapi yang sayangnyer kek butter cream putih tu cheese cake lah konon nyer (instant cake dalam kotak beli kat Tesco) nampak kat gambar bukan main lagi...meleleh air liur nengok gambar dia display kat kotak...Tapi bila dah masak bak kata Kak Zie only God Knows...auni makan segigit dah termuntah termonggek...so, masih ader lagi display kat dalam peti ais..sesiapa teringin meh la datang umah...uargghhhh...(x pasal2 kena saman plak ngan Kementerian Kesihatan nanti..buat orang termuntah2) baik tak yah ler ...
saya seorang yang lactose pada susu tepung...masa pregnant kan Umar Asif,saya daha try semua jenis susu tepung tapi semua saya lactose..aper itu lactose?kesan nyer mcm mn?----sebelum saya tahu saya seorang yang lactose pada susu tepung ni,saya try minum susu mamil tp kesan nyer saya sakit perut,buang air besar cirit sikit,kentut busuk(sori klu bunyi mcm kotor,sekadar perkongsian jer tau),pastu saya try susu enfa n semua yang lain pon sama kesan nyer...last sekali saya jumpa doctor n bagi tau nyer dan rupe² nyer saya lactose pada susu,perut saya xleh sesuai ngan susu tepung..jadi akhirnyer saya minum HL,tu pun permulaannyer kesannyer masih sama tapi x ketara sgt so saya proceed HL dan juga DUTCH LADY dalam kotak tu sahaja sb memula sahaja saya sakit perut pastu ok dan ok...sampai bertimbun² kotak² itu semua di celah sudut umah saya masa tu..tapi kali ni,suami saya masih lagi cadangkan susu tepung,tapi saya xyakin takut rugi nnti beli pastu tercirit pastu x minum..klu ader yang mcm 3 in 1 tu ok ...
well spanjang demam yg tak leh handle hari tuh mmg aku nangis , sebab sakit sangat . rasa cam nak pecah kepala jer...n jgn marah yer smua saya tak gie klinik just amik panadol sebab saya nie DEGIL org nyer just ader satu hari tuh ...memmg saya tak tido spanjang malam because sakit n couldnt take it anymore,......dah lah sakit yg menambah peritnya...takder tmpt mgadu...pon...mula lah masa tuh macam bermain di kepala hotak berkecamuk semua nya jadi..... mmg nangis tak ingat n i meraung panggil my mum...n hoping to fall a sleep ....but it takes time ...
Alan Alda is Trying to Find the Next Carl Sagan Miles OBrien reports on a contest created by actor Alan Alda, which challenges scientists to flex their communication muscles by answering the seemingly simple question, "What is a flame?" Thousands of 11-year-olds serve as judges.. ...
I had this album and really liked it. I wish I could find it in a digital format. Id buy it again. I had a penchant for somewhat obscure bands in those days, I guess I still do. Totally disagree with any Roxy music comparison. As I recall, its been a while, they seemed to bridge that spot between the rock and roll of the day and the hard core new wave, sometimes ahead of the curve and sometimes woefully behind. But the album was entertaining and definitaly listenable. For some reason overnight jets has stayed with me... ...
I had this album and really liked it. I wish I could find it in a digital format. Id buy it again. I had a penchant for somewhat obscure bands in those days, I guess I still do. Totally disagree with any Roxy music comparison. As I recall, its been a while, they seemed to bridge that spot between the rock and roll of the day and the hard core new wave, sometimes ahead of the curve and sometimes woefully behind. But the album was entertaining and definitaly listenable. For some reason overnight jets has stayed with me... ...
Expression of AKR1B1 (ALDR1, AR) in colon tissue. Antibody staining with HPA026425, HPA052751, CAB027391 and CAB047353 in immunohistochemistry.
To know about L Alanine - L-Alanine is non-polar amino acid. L-Alanine synthesized by the muscle cells from lactic acid and plays a vital role as a building block
You are viewing an interactive 3D depiction of the molecule 3-(3-hydroxy-2-oxo-2,3-dihydro-1h-indol-3-yl)-l-alanine (C11H12N2O4) from the PQR.
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DNA replication is a form of template-directed polymerization that occurs with the aid of numerous enzymes. By developing a DNA replication mimic that can undergo template-directed polymerization without enzymes, the scope of template-directed polymerization will be broadened beyond biological systems. One template-directed polymerization method that has proven successful is reductive amination on a DNA template, a two-step polymerization reaction involving equilibrium imine formation followed by reduction of the imine to the amine. Because DNA-directed reductive amination is an information transfer system, it should proceed with fidelity; however, the extent of fidelity must be explored. These studies will require the ability to sequence the resulting ANP products formed under different reaction conditions Because traditional sequencing techniques for nucleic acids and polypeptides will not work to sequence ANP, we propose to study the fidelity of DNA-directed reductive amination by sequencing ...
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Sodium triacetoxyborohydride has emerged as one of the reagents used most frequently for carrying out reductive amination of carbonyl compounds, a reaction that is also known as reductive alkylation of amines. A disadvantage of sodium triacetoxyborohydride is its poor solubility, and that product isolation requires an aqueous quench followed by liquid-liquid extraction and column chromatography.. Biotage® MP-Triacetoxyborohydride was developed to perform in a manner similar to that of sodium triacetoxyborohydride, while simplifying reagent handling and product purification. Moreover, for many of these reactions, a scavenger resin may be added for one-pot purification of the product.. ...
Only two ARC/Galleys left and I am all caught up! The same publicist who sent me Finally Out reached out about this book and the title had enough humor in it I figured it was worth a shot.* I enjoyed this so much more than I thought I would!. What Alan Alda-I didnt even recognize him from M*A*S*H (IMDb link), I just recognized his caricature-is doing is what the Plain English Campaign (website) has been trying to do since the late 70s, just through a different venue: improv. Both are trying to get things translated from the indecipherable jargon of science or government into easily relatable language. Alda, has basically made a side career out of this with the Alan Alda Center for Communicating Science at Stony Brook University, where the observations he made from his many years on Scientific American Frontiers are put into practice to teach scientists how to talk to non-scientists.. Continue reading "Book 507: If I Understood You, Would I Have This Look on My Face? - Alan Alda" →. ...
Assalamualaikum dan selamat sejahtera... arini skola amik cuti so bleh la berjimba2 kat sini jap.. lama da wat nih... dah jadi baja dah pon.. sori ehh.... hehe... sebelum terlupa, nak mintak maap yer sape2 yg tanya mana pegi sbox hanamemories tuh sebenonyer dah lama kene tendang! jatuh talak 3! malas nak rujuk dah..haha.. bg mereka2 yang biasa komen kat situ dan takleh nak regis sbg blogger, bleh ajukan apa2 persoalan kat emel yg ader kat side bar tuh eh... sori selori sekontena.. sebut psl kontena, arini barulah sampai brg2 kontena tuh ke kuantan... nak bukak and kemas balik tuh yg malessssss bangettt....... ada sape nak tulunnn?? huh! but siputih masih lg dalam proses... yg tuh lambat sket la... tp alhamdulillah rezeki sihitam dah tiba dulu.. :D .. k jom tengok resepi... resepi lama boleh tengok SINI or SINI cuma aku edit sket ...
Description: Aldehydes and ketones can be converted into amines, through formation of an imine and treatment with a reducing agent. This is called
prw:PsycPRwf_0782 K01775 alanine racemase [EC:5.1.1.1] , (GenBank) alanine racemase (A) MRSASIILDSKALTHNLNCVIDTVPDTTKVLAMVKADAYGHGIAHCLPALKDADGLGVAC FTEAQHIRELGWDKILVLIEGVFSETEWQQSIEAQCQSIIHHQDQVQWALNHLPPENSPC RTVWLKLNTGMNRLGFESDELGDVAQSLVDAGYELILTSHFANADAPNHPSNAKQIDTFT QALQQLREQVDPSIKASLCNSAGILNFKACHFDWVRPGIMLYGSSPVEGVSAQMLKLKPV MSFKASLMAIHNIAAGTSVGYGSRFVANRPIVKGIVSIGYGDGYPRVVDGSAWVSVQLAG EHSSYKCPVIGRVAMDMIAIDLTDVPNPKVGSQVMLWGDPELGAPSVDEIAESAHTLGYE LLCRVTQRPLREVL ...
hip:CGSHiEE_05465 K01775 alanine racemase [EC:5.1.1.1] , (GenBank) alr; alanine racemase (A) MNVKPATAKISSHALKQNLEIIKQKAPNSKIIAVVKANAYGHGVVFVASTLEQNVDCFGV ARLEEALALRSNGITKPILLLEGFFNEQDLPILAVNNIETVVHNHEQLEALKRSNLPSPI KVWLKIDTGMHRLGVALDEVDYFYQELKKLPQIQPHLGFVSHFSRADELESDYTQLQINR FLSATKDKQGERTIAASGGILFWPKSHLECIRPGIIMYGISPTDTIGKEFGLTPVMNLTS SLIAVRHHKQGDPVGYGGIWTSPRDTKIGVVAMGYGDGYPRDVPEGTPVYLNGRLVPIVG RVSMDMLTVDLGADSQDLVGDEVILWGKELPIETVAKFTGILSYELITKLTPRVITEYVD ...
Expression of AKR1B1 (ALDR1, AR) in breast tissue. Antibody staining with HPA026425, HPA052751, CAB027391 and CAB047353 in immunohistochemistry.
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Actor Alan Alda (image source: Wikipedia) hosts a new series about human origins Last night, I was looking at the TV listings and saw that there was a show c…
In a three-part series originally brodcast on PBS in January 2010, Alan Alda takes this question personally, visiting with dozens of scientists on three continents -- even undergoing an examination of his own brain ...
With this PhD project offered within the IMPRS, function analysis of fungal aldehyde dehydrogenases in T. vaccinum is intended, especially both getting a better inside into the IAA biosynthesis in T. vaccinum and investigating IAA transport in ectomycorrhizal fungi. Ethanol detoxification could be proven since overexpressing ald1 mutants showed increased ethanol stress tolerance. In the T. vaccinum genome seven further ald genes could be annotated, which are analyzed by qPCR for induction by chemical triggers like alcohols, aldehydes and biotic signals. To link between systemic reactions of the tree to one or more specific root factors, like mycorrhiza, a volatile collection system was developed, which allows us to characterize changes in the volatile pattern of young coniferous trees ...
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alanine: Either of two amino acids, one of which, L-alanine, or alpha-alanine (α-alanine), is a constituent of proteins. An especially rich source of L-alanine is silk fibroin, from which...
Directed by Antony Alda. With Scott Bakula, Edie Dearing, Beverly Taylor, Marissa Jaret Winokur. A has-been actor drops from public view and is presumed dead and when Hollywood decides to make a movie about his life, he decides to make a comeback by assuming another identity.
Brack, W., Altenburger, R., Schüürmann, G., Krauss, M., López Herráez, D., van Gils, J., Slobodnik, J., Munthe, J., Gawlik, B.M., van Wezel, A., Schriks, M., Hollender, J., Tollefsen, K.E., Mekenyan, O., Dimitrov, S., Bunke, D., Cousins, I., Posthuma, L., van den Brink, P.J., López de Alda, M., Barceló, D., Faust, M., Kortenkamp, A., Scrimshaw, M., Ignatova, S.N., Engelen, G., Massmann, G., Lemkine, G., Teodorovic, I., Walz, K.-H., Dulio, V., Jonker, M.T.O., Jäger, F., Chipman, K., Falciani, F., Liska, I., Rooke, D., Zhang, X., Hollert, H., Vrana, B., Hilscherova, K., Kramer, K., Neumann, S., Hammerbacher, R., Backhaus, T., Mack, J., Segner, H., Escher, B., De Aragão Umbuzeiro, G., (2015 ...
Beta Alanine list and information including what is Beta Alanine, health benefits and usage indications. Find articles and product list for other top low-carb products, fat-burners, nutrition bars and shakes.
The overall grade for beta alanine is 2 out of 3 meaning there is some evidence that this supplement does some (not all) of what it claims. Using Beta Alanine may lead to some improvements.
I want to add beta alanine to my supplement stack. I was wondering when i should take it and how much? Should i take it on off days and does it have
Beta Alanine is a rather popular ingredient used in many pre workout supplements that is responsible for that tingling feeling you get after ingesting it.
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The development of intermolecular alkene aminopyridylation has great potential for quickly increasing molecular complexity with two valuable groups. Here we report a strategy for the photocatalytic aminopyridylation of alkenes using a variety of N-aminopyridinium salts as both aminating and pyridylating reagents. Using Eosin Y as a photocatalyst, amino and pyridyl groups are simultaneously incorporated into alkenes, affording synthetically useful aminoethyl pyridine derivatives under mild reaction conditions. Remarkably, the C4-regioselectivity in radical trapping with N-aminopyridinium salt can be controlled by electrostatic interaction between the pyridinium nitrogen and sulfonyl group of β-amino radical. This transformation is characterized by a broad substrate scope, good functional group compatibility, and the utility of this transformation was further demonstrated by late-stage functionalization of complex biorelevant molecules. Combining experiments and DFT calculations on the mechanism ...
Ader, Robert (Ed.) Psychoneuroimmunology. Academic Press. New York, 1981.. Ader, Robert and N. Cohen. Behaviorally conditioned immunosuppression and Nurine Systemic Lupus Erythematosus.Science. 1982. 215: pp. 1534-1536.. Amkraut, A., and G.F. Solomon. From the Symbolic Stimulus to the Pathophysiologic Response: Immune Mechanisms. Internationa JQurna1 of Psychiatry in Medicine. Vol. 5, No. 4. (1975) pp. 541-563.. Anderson, Alan. How the Mind Heals. Psychology Todav. 16(12), pp. 51-56.. Auerbach, Jeffroy E., Terrence D. Oleson, George F. Solomon.A Behavioral Medicine Intervention as an Adjunctive Treatment for HIV-Related Illness. Behavioral Medicine.. Brosnan-Rayner, Establishing Relevance for the Use of Psychoimmune Interventions to Improve HIV Progression Time and Personal Control. National Center for HIV Social Research, Royal Brisbane Hospital, Australia.. Buchbinder, S.P., M. Datz, N. Hessol, et al. Why Do Some Patients With HIV Live Longer, Healthier Lives? AIDS Alert. pp. ...
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The enzyme from the plants Lathyrus odoratus (sweet pea) and L. sativus (grass pea) also forms 3-(5-oxoisoxazolin-4-yl)-L-alanine in vitro (cf. EC 2.5.1.119). However, on
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Mei 2004: Peter Lagast (instalraam, crox 119). Dirk Peers (hommage, crox 120).. Mei 2005: instalraam Rik Soenen. Projecten van Anja Hellebaut en Samir Boudia. Spetterend optreden van het trio Final Detail. Publicatie van 2 crox-cards met werk van Anja Hellebaut. Recensie in ,Foto+ (rubriek Galeriemania). Bevestiging van de erkenning door de Vlaamse Gemeenschap als Beeldend Kunstcentrum. Het mega-project BRAINBOX wordt uitgesteld tot najaar 2006.. Mei 2006: Sequel van BASICS 2 in Abdij Maagdendale (Oudenaarde). Projecten van Johan De Wilde (crox 178), Lucia Penninckx (crox 179) en Alda Snopek (crox 180). Project van Mario De Brabandere in de mediaruimte. Publicatie van croxboek NR 2, PARTICLES, van Johan De Wilde. Publicatie van een nieuwe reeks croxcards. De Algemene Ledenvergadering stelt Johan De Wilde aan als nieuw bestuurslid en keurt de nieuwe statuten goed. Sjoerd Paridaen treedt aan als voorzitter van het crox-bestuur, Joris Van der Borght als penningmeester.. Mei 2007: PRINCIPIUM (crox ...
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In the reaction of 2,6-dichloropyridine and 2,6-dichloro-3-phenylpyridine with potassium amide in liquid ammonia at -70°C, formation of derivatives of 4,4-bipyridyl and 3,4-bipyridyl is observed. The 4,4 coupling products are far in excess to the 3,4 coupling products. When the reaction is carried out at -70°C in the presence of potassium permanganate, the corresponding 4-aminopyridines are the main products. 2-Chloro-6-phenoxypyridine is very unreactive with this aminating reagent at -70°C as well as -33°C, but in the presence of potassium permanganate at -33°C 4-amino-2-chloro-6-phenoxypyridine is formed in fair yield. The mechanisms of the formation of the bipyridyls and 4-aminopyridines are presented.. ...
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The SCOP classification for the Alanine racemase C-terminal domain-like superfamily including the families contained in it. Additional information provided includes InterPro annotation (if available), Functional annotation, and SUPERFAMILY links to genome assignments, alignments, domain combinations, taxonomic visualisation and hidden Markov model information.
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Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY ...
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Join stage and screen legend Alan Alda and Lawrence Krauss for an intimate evening of conversation for the inaugural Origins Project Dialogue. Science and Art: Long Lost Lovers is a candid and unscripted conversation on the importance of scientific literacy and the role of science and creativity in our society. A thought-provoking and interesting night in the beautifully restored Orpheum Theatre in downtown Phoenix.. ...
Active site of A. baumannii alanine racemase. (a) 2Fo− Fc electron-density map of the active site contoured at 1.0σ with isomesh map shown (1.6 Å carve).
Accepted name: alanine racemase. Reaction: L-alanine = D-alanine. Other name(s): L-alanine racemase. Systematic name: alanine racemase. Comments: A pyridoxal-phosphate protein.. Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9024-06-0. References:. 1. Marr, A.G. and Wilson, P.W. The alanine racemase of Brucella abortus. Arch. Biochem. Biophys. 49 (1954) 424-433.. 2. Wood, W.A. Amino acid racemases. Methods Enzymol. 2 (1955) 212-217.. 3. Wood, W.A. and Gunsalus, I.C. D-Alanine formation: a racemase in Streptococcus faecalis. J. Biol. Chem. 190 (1951) 403-416.. ...
Polimixinas são antibióticos com uma estrutura genética constituída de um peptídeo cíclico com uma longa cauda hidrofóbica. Elas quebram a estrutura da membrana celular bacteriana ao interagir com seus fosfolípidos. Eles são produzidos por sistemas de sintase de peptídeos não-ribossômicos em bactérias Gram-positivas como a Paenibacillus polymyxa e são seletivamente tóxicas a bactérias Gram-negativas devido à sua especificidade pelas moléculas de lipopolissacarídeo que existem nas membranas externas das Gram-negativas. Polimixinas B e E (também conhecidas como colistinas) são usadas no tratamento de infecções bacterianas do tipo Gram-negativo. O problema global de resistência antimicróbica crescente levou ao interesse em seu uso recentemente. A polimixina M é também conhecida como "mattacin". AS bactérias Gram-negativas podem desenvolver resistência às polimixinas por meio de várias modificações de suas estruturas lipopolissacarídeas que inibem a aderência das ...
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L-Alanine Assay Kit (ab83394). Sensitivity: 24 μg/mL. Colorimetric or fluorometric detection of alanine in a variety of biological samples in 40 min.
Alanine (or aminopropionic acid) is an aliphatic (aromatic-free) amino acid. In the liver, it is easily processed into a glucose source of energy for the body,

L Alanine Dehydrogenase - Medical Dictionary online-medical-dictionary.orgL Alanine Dehydrogenase - Medical Dictionary online-medical-dictionary.org

L Alanine Dehydrogenase. An NAD-dependent enzyme that catalyzes the reversible Deamination of L-Alanine to PYRUVATE and Ammonia ... The enzyme is needed for Growth when Alanine is the sole Carbon or Nitrogen source. It may also play a Role in Cell Wall ... synthesis because L-Alanine is an important constituent of the PEPTIDOGLYCAN layer. ...
more infohttp://www.online-medical-dictionary.org/definitions-l/l-alanine-dehydrogenase.html

Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 (IPR008143) | InterPro | EMBL-EBIAlanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 (IPR008143) | InterPro | EMBL-EBI

Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine. Pyridine nucleotide ... Alanine dehydrogenases (EC:1.4.1.1) and pyridine nucleotide transhydrogenase (EC:1.6.1.1) have been shown to share regions of ... The sequence of alanine dehydrogenase from several bacterial species are related with those of the alpha subunit of bacterial ... Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 (IPR008143). Short name: Ala_DH/PNT_CS2 ...
more infohttp://www.ebi.ac.uk/interpro/entry/IPR008143

RCSB PDB 









- 1OMO: alanine dehydrogenase dimer w/bound NAD (archaeal) Methods Report PageRCSB PDB - 1OMO: alanine dehydrogenase dimer w/bound NAD (archaeal) Methods Report Page

Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and ...
more infohttp://www.rcsb.org/pdb/explore/materialsAndMethods.do?structureId=1OMO

Alanine dehydrogenase - WikipediaAlanine dehydrogenase - Wikipedia

L-alanine dehydrogenase, NAD+-linked alanine dehydrogenase, alpha-alanine dehydrogenase, NAD+-dependent alanine dehydrogenase, ... alanine oxidoreductase, and NADH-dependent alanine dehydrogenase. T Alanine dehydrogenase contains both a N-terminus and C- ... Alanine dehydrogenase (EC 1.4.1.1) is an enzyme that catalyzes the chemical reaction L-alanine + H2O + NAD+ ⇌ {\displaystyle \ ... OConnor RJ, Halvorson H (March 1961). "The substrate specificity of L-alanine dehydrogenase". Biochimica et Biophysica Acta. ...
more infohttps://en.wikipedia.org/wiki/Alanine_dehydrogenase

An Amperometric Biosensor Based on Alanine Dehydrogenase for the Determination of Low Level of Ammonium Ion in WaterAn Amperometric Biosensor Based on Alanine Dehydrogenase for the Determination of Low Level of Ammonium Ion in Water

... Tan Ling ... Tan Ling Ling, Musa Ahmad, and Lee Yook Heng, "An Amperometric Biosensor Based on Alanine Dehydrogenase for the Determination ...
more infohttps://www.hindawi.com/journals/js/2011/980709/cta/

An Amperometric Biosensor Based on Alanine Dehydrogenase for the Determination of Low Level of Ammonium Ion in WaterAn Amperometric Biosensor Based on Alanine Dehydrogenase for the Determination of Low Level of Ammonium Ion in Water

... Tan Ling ... ion detection by immobilising alanine dehydrogenase (AlaDH) enzyme in a photocurable methacrylic membrane made up of poly(2- ...
more infohttps://www.hindawi.com/journals/js/2011/980709/abs/

Host vector system for high-level expression and purification of recombinant, enzymatically active alanine dehydrogenase of...Host vector system for high-level expression and purification of recombinant, enzymatically active alanine dehydrogenase of...

The 40-kDa antigen of M. tuberculosis, which is an alanine dehydrogenase, is a species-specific antigen that is potentially ... Host vector system for high-level expression and purification of recombinant, enzymatically active alanine dehydrogenase of ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/9661660?dopt=Abstract

ala - Alanine dehydrogenase - Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) - ala gene...ala - Alanine dehydrogenase - Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) - ala gene...

... dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its ... alanine dehydrogenase activity Source: UniProtKB ,p>Inferred from Direct Assay,/p> ,p>Used to indicate a direct assay for the ... "A novel archaeal alanine dehydrogenase homologous to ornithine cyclodeaminase and mu-crystallin.". Schroder I., Vadas A., ... "A novel archaeal alanine dehydrogenase homologous to ornithine cyclodeaminase and mu-crystallin.". Schroder I., Vadas A., ...
more infohttps://www.uniprot.org/uniprot/O28608

The effect of multilayer gold nanoparticles on the electrochemical response of ammonium ion biosensor based on alanine...The effect of multilayer gold nanoparticles on the electrochemical response of ammonium ion biosensor based on alanine...

... ion biosensor based on alanine dehydrogenase (AlaDH) was investigated. The approach of the study was based on construction of ... of multilayer gold nanoparticles on the electrochemical response of ammonium ion biosensor based on alanine dehydrogenase ... of multilayer gold nanoparticles on the electrochemical response of ammonium ion biosensor based on alanine dehydrogenase ...
more infohttp://scholarbank.nus.edu.sg/handle/10635/95226

RCSB PDB 









for 1OMORCSB PDB for 1OMO

Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and ... alanine dehydrogenase A, B 322 Archaeoglobus fulgidus EC#: 1.4.1.1 IUBMB Gene Name(s): ala AF_1665 ...
more infohttp://www.rcsb.org/pdb/explore/biologyAndChemistry.do?structureId=1OMO

nature.com searchnature.com search

Glutamic and Alanine Dehydrogenase Determined by One Gene in Neurospora Crassa *R. R. BÜRK ... Rights & permissionsfor article Glutamic and Alanine Dehydrogenase Determined by One Gene in ,i,Neurospora Crassa,/i, . Opens ...
more infohttps://www.nature.com/search?author=%22R.%20Burk%22&error=cookies_not_supported&code=de259f88-8934-4903-a12e-4d35cabcbdf9

Springer Handbook of Enzymes | SpringerLinkSpringer Handbook of Enzymes | SpringerLink

Alanine dehydrogenase Pages 1-26 * Glutamate dehydrogenase Pages 27-42 * Glutamate dehydrogenase [NAD(P)+] ...
more infohttps://link.springer.com/book/10.1007/3-540-37646-1

The complete genome sequence of Mycobacterium bovis | PNASThe complete genome sequence of Mycobacterium bovis | PNAS

... encoding alanine dehydrogenase, is a pseudogene, therefore blocking the conversion of alanine to pyruvate. ... PGL, phenolic glycolipid; G3P, glycerol 3-phosphate; DHAP, dihydroxyacetone phosphate; PEP, phosphoenolpyruvate; Ald, alanine ...
more infohttps://www.pnas.org/content/100/13/7877?ijkey=fc9bfa59d442b26fca83901e55f06d444c2c95fc&keytype2=tf_ipsecsha

dadA - D-amino acid dehydrogenase - Escherichia coli (strain K12) - dadA gene & proteindadA - D-amino acid dehydrogenase - Escherichia coli (strain K12) - dadA gene & protein

... but not on L-alanine. Participates in the utilization of L-alanine and D-alanine as the sole source of carbon, nitrogen and ... Has broad substrate specificity; is mostly active on D-alanine, and to a lesser extent, on several other D-amino acids such as ... D-amino acid dehydrogenase (dadA). This subpathway is part of the pathway D-alanine degradation, which is itself part of Amino- ... but not on L-alanine. Participates in the utilization of L-alanine and D-alanine as the sole source of carbon, nitrogen and ...
more infohttp://www.uniprot.org/uniprot/P0A6J5

Enzyme Explorer Assay Library | Sigma-AldrichEnzyme Explorer Assay Library | Sigma-Aldrich

L-Alanine Dehydrogenase 1.4.1.1. Alcohol Dehydrogenase 1.1.1.1. Alcohol Dehydrogenase, NADP+ Dependent 1.1.1.2. ... R)-Aromatic Alcohol Dehydrogenase, NADP+ Dependent (EC 1.1.1.2) 1.1.1.2. (S)-Aromatic Alcohol Dehydrogenase, NADP+ Dependent ( ...
more infohttps://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/learning-center/assay-library.html

CDD Conserved Protein Domain Family: AlaDh PNT CCDD Conserved Protein Domain Family: AlaDh PNT C

Alanine dehydrogenase/PNT, C-terminal domain. This family now also contains the lysine 2-oxoglutarate reductases. ...
more infohttps://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam01262

New Classes of Alanine Racemase Inhibitors Identified by High-Throughput Screening Show Antimicrobial Activity against...New Classes of Alanine Racemase Inhibitors Identified by High-Throughput Screening Show Antimicrobial Activity against...

... alanine by alanine racemase is coupled to the deamination of L-alanine to pyruvate by the NAD-dependent L-alanine dehydrogenase ... D-alanine, L-alanine, L-alanine dehydrogenase (Bacillus subtilis), and β-NAD-sodium salt were purchased from Sigma Aldrich (St ... Alanine racemase and L-alanine dehydrogenase assay adaptation to 384-well format. The coupled alanine racemase assay of Esaki ... The assay was modified by varying the concentrations of alanine racemase, D-alanine, NAD, and L-alanine dehydrogenase in a ...
more infohttp://pubmedcentralcanada.ca/pmcc/articles/PMC3102704/?lang=en-ca

Enzyme | Scientist SolutionsEnzyme | Scientist Solutions

Alanine Dehydrogenase. Alcohol Dehydrogenase. Aminolevulinate Synthase. Assay and Purification of Enzymes-Oxalate Decarboxylase ...
more infohttp://www.scientistsolutions.com/forum/biochemistry-enzymology/enzyme

Phycobilisomes
     Summary Report | CureHunterPhycobilisomes Summary Report | CureHunter

Alanine Dehydrogenase 9. Cytochrome b6f Complex 10. Light-Harvesting Protein Complexes CureHunter Inc. provides medical ...
more infohttp://www.curehunter.com/public/keywordSummaryD045524-Phycobilisomes.do

AlaDh PNT N (SM01003) | InterPro | EMBL-EBIAlaDh PNT N (SM01003) | InterPro | EMBL-EBI

Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (IPR007886) Member database. SMART. SMART (a Simple ...
more infohttp://www.ebi.ac.uk/interpro/signature/SM01003

Enhanced calcium carbonate-biofilm complex formation by alkali-generating Lysinibacillus boronitolerans YS11 and alkaliphilic...Enhanced calcium carbonate-biofilm complex formation by alkali-generating Lysinibacillus boronitolerans YS11 and alkaliphilic...

Then, 5 µl of l-glutamate dehydrogenase was added to each sample and incubated for 5 min at 30 °C. The absorbance of each ... alanine, cystathionine, and glucosamine-6-phosphate (Fig. 2c).. Open image in new window. ... 2c). Ammonia production from other amino acids deamination pathways, including glutamate dehydrogenase, arginine deaminase, and ... glutamate transport and glutamate dehydrogenase activity, (4) threonine deaminase activity, and (5) serine deaminase activity. ...
more infohttps://link.springer.com/article/10.1186%2Fs13568-019-0773-x

KEGG BRITE: KEGG Orthology (KO) - Mycobacterium tuberculosis HaarlemKEGG BRITE: KEGG Orthology (KO) - Mycobacterium tuberculosis Haarlem

... alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] K00259 ald; alanine dehydrogenase [EC:1.4.1.1] K01940 argG; ... TBHG_02712 secreted L-alanine dehydrogenase Ald TBHG_01620 argininosuccinate synthase ArgG TBHG_01621 argininosuccinate lyase ... TBHG_02416 NAD-dependent glutamate dehydrogenase Gdh TBHG_01170 pyrroline-5-carboxylate dehydrogenase RocA TBHG_01833 glutamine ... TBHG_00234 succinate-semialdehyde dehydrogenase [NADP] dependent GabD1 TBHG_01688 succinate-semialdehyde dehydrogenase GabD2 ...
more infohttp://www.genome.jp/kegg-bin/get_htext?mtul00001+TBHG_00332

The D-alanyl-d-alanine carboxypeptidase enzyme is essential for virulence in the Schu S4 strain of Francisella tularensis and a...The D-alanyl-d-alanine carboxypeptidase enzyme is essential for virulence in the Schu S4 strain of Francisella tularensis and a...

Alanine Dehydrogenase. An NAD-dependent enzyme that catalyzes the reversible DEAMINATION of L-ALANINE to PYRUVATE and AMMONIA. ... β-alanine Supplementation on Knee Extensor Contractile and Force Properties. Carnosine (made by bonding β-alanine and histidine ... Alanine Transaminase. An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. ( ... Effect of β-alanine Supplementation on Muscle Carnosine. Carnosine is a natural acid buffering substance of muscle. The primary ...
more infohttps://www.bioportfolio.com/resources/pmarticle/2478049/The-D-alanyl-d-alanine-carboxypeptidase-enzyme-is-essential-for-virulence-in.html

SMART: AlaDh PNT C domain annotationSMART: AlaDh PNT C domain annotation

Alanine dehydrogenase catalyses the NAD-dependent reversible reductive amination of pyruvate into alanine. Pyridine nucleotide ... Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine. ... L-ALANINE DEHYDROGENASE COMPLEXED WITH NAD. 1ptj. Crystal structure analysis of the DI and DIII complex of transhydrogenase ... Crystal structure of alanine dehydrogenase from themus thermophilus. 2fr8. Structure of transhydrogenase (dI.R127A.NAD+)2(dIII. ...
more infohttp://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01002
  • Other names in common use include AlaDH, L-alanine dehydrogenase, NAD+-linked alanine dehydrogenase, alpha-alanine dehydrogenase, NAD+-dependent alanine dehydrogenase, alanine oxidoreductase, and NADH-dependent alanine dehydrogenase. (wikipedia.org)
  • The use of multilayer of gold nanoparticles (AuNPs) attached on gold electrode surface via thiol chemistry to fabricate an ammonium (NH 4 +) ion biosensor based on alanine dehydrogenase (AlaDH) was investigated. (nus.edu.sg)
  • The two enzymes involved in lysinebreakdown, lysine 2-oxoglutarate reductase (also known as lysinea-ketoglutarate reductase) and saccharopine dehydrogenase exist as asingle bifunctional protein, with the former activity being regulated bylysine availability, calcium and phosphorylation/ dephosphorylation. (embl.de)
  • is mostly active on D-alanine, and to a lesser extent, on several other D-amino acids such as D-methionine, D-serine and D-proline, but not on L-alanine. (uniprot.org)
  • Residues from both monomers contribute to the two active sites, where PLP and alanine bind. (pubmedcentralcanada.ca)