A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance. Bilateral FRONTAL LOBE dysfunction involving the anterior cingulate gyrus and related brain injuries are associated with this condition. This may result in impaired abilities to communicate and initiate motor activities. (From Adams et al., Principles of Neurology, 6th ed, p348; Fortschr Neurol Psychiatr 1995 Feb;63(2):59-67)
The inability to generate oral-verbal expression, despite normal comprehension of speech. This may be associated with BRAIN DISEASES or MENTAL DISORDERS. Organic mutism may be associated with damage to the FRONTAL LOBE; BRAIN STEM; THALAMUS; and CEREBELLUM. Selective mutism is a psychological condition that usually affects children characterized by continuous refusal to speak in social situations by a child who is able and willing to speak to selected persons. Kussmal aphasia refers to mutism in psychosis. (From Fortschr Neurol Psychiatr 1994; 62(9):337-44)
The exchange or transmission of ideas, attitudes, or beliefs between individuals or groups.
General or unspecified injuries involving the leg.
Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
A subfield of psychiatry that emphasizes the somatic substructure on which mental operations and emotions are based, and the functional or organic disturbances of the central nervous system that give rise to, contribute to, or are associated with mental and emotional disorders. (From Campbell's Psychiatric Dictionary, 8th ed.)
Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.
Planned post-marketing studies of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques that have been approved for general sale. These studies are often conducted to obtain additional data about the safety and efficacy of a product. This concept includes phase IV studies conducted in both the U.S. and in other countries.
Surveillance of drugs, devices, appliances, etc., for efficacy or adverse effects, after they have been released for general sale.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
The interactions between physician and patient.
Those individuals engaged in research.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
A subclass of histone deacetylases that are NAD-dependent. Several members of the SIRTUINS family are included in this subclass.
A homologous family of regulatory enzymes that are structurally related to the protein silent mating type information regulator 2 (Sir2) found in Saccharomyces cerevisiae. Sirtuins contain a central catalytic core region which binds NAD. Several of the sirtuins utilize NAD to deacetylate proteins such as HISTONES and are categorized as GROUP III HISTONE DEACETYLASES. Several other sirtuin members utilize NAD to transfer ADP-RIBOSE to proteins and are categorized as MONO ADP-RIBOSE TRANSFERASES, while a third group of sirtuins appears to have both deacetylase and ADP ribose transferase activities.
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.
A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
A sirtuin family member found primarily in the CYTOPLASM. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.
Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.
Hand-held tools or implements used by health professionals for the performance of surgical tasks.
A technique that induces the processing of disturbing memories and experiences, by stimulating neural mechanisms that are similar to those activated during REM sleep. The technique consists of eye movements following side-to-side movements of the index and middle fingers, or the alternate tapping of the hands on the knees. This procedure triggers the processing of information, thus facilitating the connection of neural networks.
A name originally applied to a group of skin diseases characterized by the formation of fine, branny scales, but now used only with a modifier. (Dorland, 27th ed)
A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Programs of disease surveillance, generally within health care facilities, designed to investigate, prevent, and control the spread of infections and their causative microorganisms.
A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Analog or digital communications device in which the user has a wireless connection from a telephone to a nearby transmitter. It is termed cellular because the service area is divided into multiple "cells." As the user moves from one cell area to another, the call is transferred to the local transmitter.
Computer programs or software installed on mobile electronic devices which support a wide range of functions and uses which include television, telephone, video, music, word processing, and Internet service.
A type of MICROCOMPUTER, sometimes called a personal digital assistant, that is very small and portable and fitting in a hand. They are convenient to use in clinical and other field situations for quick data management. They usually require docking with MICROCOMPUTERS for updates.
A scale that assesses the response to stimuli in patients with craniocerebral injuries. The parameters are eye opening, motor response, and verbal response.
A state of unconsciousness as a complication of diabetes mellitus. It occurs in cases of extreme HYPERGLYCEMIA or extreme HYPOGLYCEMIA as a complication of INSULIN therapy.
A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
A transmissible spongiform encephalopathy of cattle associated with abnormal prion proteins in the brain. Affected animals develop excitability and salivation followed by ATAXIA. This disorder has been associated with consumption of SCRAPIE infected ruminant derived protein. This condition may be transmitted to humans, where it is referred to as variant or new variant CREUTZFELDT-JAKOB SYNDROME. (Vet Rec 1998 Jul 25;143(41):101-5)
Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)
Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
Abnormal isoform of prion proteins (PRIONS) resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
Congenital conditions in individuals with a male karyotype, in which the development of the gonadal or anatomical sex is atypical.
Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.
Gonadal interstitial or stromal cell neoplasm composed of only LEYDIG CELLS. These tumors may produce one or more of the steroid hormones such as ANDROGENS; ESTROGENS; and CORTICOSTEROIDS. Clinical symptoms include testicular swelling, GYNECOMASTIA, sexual precocity in children, or virilization (VIRILISM) in females.
Databases devoted to knowledge about specific genes and gene products.
The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.
A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.
Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
A lysosomal papain-related cysteine proteinase that is expressed in a broad variety of cell types.
A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES.
A cysteine endopeptidase found in NATURAL KILLER CELLS and CYTOTOXIC T-LYMPHOCYTES. It may have a specific function in the mechanism or regulation of cytolytic activity of immune cells.
A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.

Aggravation of brainstem symptoms caused by a large superior cerebellar artery aneurysm after embolization by Guglielmi detachable coils--case report. (1/22)

An 81-year-old male presented with right oculomotor nerve paresis and left hemiparesis caused by a mass effect of a large superior cerebellar artery aneurysm. Endovascular treatment was performed using Guglielmi detachable coils. The patient subsequently suffered aggravation of the mass effect 3 weeks after the embolization. Bilateral vertebral artery occlusion was performed, which decreased the cerebral edema surrounding the aneurysm, but his neurological symptoms did not improve. Parent artery occlusion is recommended as the first choice of treatment for an unclippable large or giant aneurysm causing a mass effect on the brainstem.  (+info)

Residual cerebral activity and behavioural fragments can remain in the persistently vegetative brain. (2/22)

This report identifies evidence of partially functional cerebral regions in catastrophically injured brains. To study five patients in a persistent vegetative state (PVS) with different behavioural features, we employed [(18)F]fluorodeoxyglucose-positron emission tomography (FDG-PET), MRI and magnetoencephalographic (MEG) responses to sensory stimulation. Each patient's brain expressed a unique metabolic pattern. In three of the five patients, co-registered PET/MRI correlate islands of relatively preserved brain metabolism with isolated fragments of behaviour. Two patients had suffered anoxic injuries and demonstrated marked decreases in overall cerebral metabolism to 30-40% of normal. Two other patients with non-anoxic, multifocal brain injuries demonstrated several isolated brain regions with relatively higher metabolic rates, that ranged up to 50-80% of normal. Nevertheless, their global metabolic rates remained <50% of normal. MEG recordings from three PVS patients provide clear evidence for the absence, abnormality or reduction of evoked responses. Despite major abnormalities, however, these data also provide evidence for localized residual activity at the cortical level. Each patient partially preserved restricted sensory representations, as evidenced by slow evoked magnetic fields and gamma band activity. In two patients, these activations correlate with isolated behavioural patterns and metabolic activity. Remaining active regions identified in the three PVS patients with behavioural fragments appear to consist of segregated corticothalamic networks that retain connectivity and partial functional integrity. A single patient who suffered severe injury to the tegmental mesencephalon and paramedian thalamus showed widely preserved cortical metabolism, and a global average metabolic rate of 65% of normal. The relatively high preservation of cortical metabolism in this patient defines the first functional correlate of clinical- pathological reports associating permanent unconsciousness with structural damage to these regions. The specific patterns of preserved metabolic activity identified in these patients do not appear to represent random survivals of a few neuronal islands; rather they reflect novel evidence of the modular nature of individual functional networks that underlie conscious brain function. The variations in cerebral metabolism in chronic PVS patients indicate that some cerebral regions can retain partial function in catastrophically injured brains.  (+info)

Posterior encephalopathy subsequent to cyclosporin A presenting as irreversible abulia. (3/22)

A case of cyclosporin A (Cys A)-induced posterior encephalopathy developed into persistent abulia despite rapid and marked improvement of abnormal T2- and FLAIR MRI hyperintense regions. Diffusion-weighted MRI signal intensity was also high at the onset. This change is atypical in Cys A-induced encephalopathy and was thought to predict poor recovery from the encephalopathy. Persistent abulia was probably due to marked hypoperfusion in the whole cortex including bilateral frontal lobes and basal ganglia as detected by SPECT. Apart from the breakdown of the blood-brain barrier, direct toxicity of Cys A to the brain may play a role in the pathogenesis of chronic, irreversible encephalopathy.  (+info)

Leukoencephalopathy induced by tegafur: serial studies of somatosensory evoked potentials and cerebrospinal fluid. (4/22)

A case of leukoencephalopathy induced by tegafur, an antineoplastic derivative of 5-FU, is reported. The patient received 600 mg of tegafur p.o. for 16 days before excision of rectal cancer. After the operation, gait disturbance and mental abnormalities appeared. He became akinetic and mute within a few days following readministration of tegafur. Serial studies of brain CT, somatosensory evoked potentials (SEP) were made, and myelin basic proteins (MBP) in the cerebrospinal fluid were measured. The level of MBP was about twice the normal value and the central conduction time (CCT) of SEP was prolonged at admission. The value of MBP and CCT improved with recovery from akinetic mutism.  (+info)

Abulia following penetrating brain injury during endoscopic sinus surgery with disruption of the anterior cingulate circuit: case report. (5/22)

BACKGROUND: It is common knowledge that the frontal lobes mediate complex human behavior and that damage to these regions can cause executive dysfunction, apathy, disinhibition and personality changes. However, it is less well known that subcortical structures such as the caudate and thalamus are part of functionally segregated fronto-subcortical circuits, that can also alter behavior after injury. CASE PRESENTATION We present a 57 year old woman who suffered penetrating brain injury during endoscopic sinus surgery causing right basal ganglia injury which resulted in an abulic syndrome. CONCLUSION: Abulia does not result solely from cortical injury but can occur after disruption anywhere in the anterior cingulate circuit--in the case of our patient, most prominently at the right caudate.  (+info)

MRI findings from a case of fulminating adult-onset measles encephalitis. (6/22)

We report a rare case of fulminating adult-onset measles encephalitis. A 34-year-old man developed a comatose state after measles eruptions and ultimately akinetic mutism. Titers of anti-measles IgM antibodies were elevated in both serum and cerebrospinal fluid. Brain magnetic resonance imaging (MRI) 3 months after onset revealed widespread hyperintense lesions in the periventricular white matter and marginal hyperintense lesions in the brainstem on fluid-attenuated inversion recovery and diffusion-weighted images. The marginal lesions in the brainstem are similar to subpial demyelinating lesions seen in postinfectious encephalomyelitis. This case of encephalitis may be related to an autoimmune-mediated process triggered by measles infection.  (+info)

Akinetic mutism after right internal watershed infarction. (7/22)

We describe a 72-year-old man who developed akinetic mutism following a cerebrovascular accident involving his right internal watershed area and responded well to dopaminergic agonists. We discuss this rare condition and the unusual unilateral location of the lesion.  (+info)

Akinetic mutism responsive to bromocriptine following subdural hematoma evacuation in a patient with hydrocephalus. (8/22)

An 11-year-old girl with obstructive hydrocephalus developed akinetic mutism after treatment for hydrocephalus due to aqueductal stenosis by ventriculoperitoneal (VP) shunting. Bilateral chronic subdural hematomas developed about 2 months after insertion of the VP shunt and were evacuated. Postoperatively, the patient developed akinetic mutism, but her condition improved after administration of bromocriptine. Absence of abnormalities on dopamine transporter single photon emission computed tomography, lack of clinical response to levodopa treatment, and normal homovanillic acid concentration in the cerebrospinal fluid all indicated normal dopamine production. Pressure on the periventricular monoamine projections in the thalamus and hypothalamus without major dopamine deprivation in the striatum may have been the most important factors in the development of akinetic mutism in this patient.  (+info)

TY - JOUR. T1 - Episodically remitting akinetic mutism following subarachnoid hemorrhage. AU - Burruss, John W.. AU - Chacko, Ranjit C.. PY - 1999/1/1. Y1 - 1999/1/1. N2 - Akinetic mutism is characterized by alertness with near complete absence of volitional activity. The authors report a case of episodicallly remitting akinetic mutism following subarachnoid hemorrhage.. AB - Akinetic mutism is characterized by alertness with near complete absence of volitional activity. The authors report a case of episodicallly remitting akinetic mutism following subarachnoid hemorrhage.. UR - http://www.scopus.com/inward/record.url?scp=0032909615&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0032909615&partnerID=8YFLogxK. U2 - 10.1176/jnp.11.1.100. DO - 10.1176/jnp.11.1.100. M3 - Article. C2 - 9990564. AN - SCOPUS:0032909615. VL - 11. SP - 100. EP - 102. JO - Journal of Neuropsychiatry and Clinical Neurosciences. JF - Journal of Neuropsychiatry and Clinical Neurosciences. SN - ...
Akinetic mutism is a medical term describing patients tending neither to move (akinesia) nor speak (mutism). Akinetic mutism was first described in 1941 as a mental state where patients lack the ability to move or speak. However, their eyes may follow their observer or be diverted by sound. Patients lack most motor functions such as speech, facial expressions, and gestures, but demonstrate apparent alertness. They exhibit reduced activity and slowness, and can speak in whispered monosyllables. Patients often show visual fixation on their examiner, move their eyes in response to an auditory stimulus, or move after often repeated commands. Patients with akinetic mutism are not paralyzed, but lack the will to move. Many patients describe that as soon as they will or attempt a movement, a counter-will or resistance rises up to meet them. Akinetic mutism varies across all patients. Its form, intensity, and clinical features correspond more closely to its functional anatomy rather than to its ...
Locked in syndrome, from stroke, TBI, ALS, encephalitis, or just intubation with paralysis or limb trauma was always a communication challenge. Now, after having it myself for a few days from an
A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance.
We studied a 70-year-old woman with a unique combination of hyperkinesia and mutism. These findings differed from akinetic mutism because there was continuous bilateral ballism and dystonia--hence the term hyperkinetic mutism. CT demonstrated bilateral calcifications in the basal ganglia, and MRI indicated bilateral watershed infarcts. Different dopaminergic mechanisms may underlie the hyperkinesia and mutism.
The behavioral features of four children with acquired neurologic mutism are reported from the Department of Neurology, University Hospital Rotterdam-Dijkzigt, Rotterdam; and Department of Medical Psychology, Ziekenhuis Walcheren, Vlissingen, The Netherlands. Neuropsychologic examinations revealed changes in phonation, orofacial movements, communicative behavior, and linguistic functions. Case 1, akinetic mutism, post severe head injury, hemorrhage in left fronto-parietal area, spastic quadriplegia, motionless except for slow eye movements and head turning when addressed, no orofacial movements except smacking of lips, recovered slow dysarthric speech after 15 months; word finding unimpaired; Case 2, aphasic mutism, post head injury coma and contusion of left hemisphere, right flaccid hemiparesis, mobility improved in 6 weeks, but aphasia persisted; Case 3, cortical deafness, post head trauma neglect for verbal and nonverbal auditory stimuli, recovery of awareness of language and sounds after 5 ...
ABSTRACT: The locked-in syndrome (pseudocoma) describes patients who are awake and conscious but selectively deefferented, i.e., have no means of producing speech, limb or facial movements. Acute ventral pontine lesions are its most common cause. People with such brainstem lesions often remain comatose for some days or weeks, needing artificial respiration and then gradually wake up, but remaining paralyzed and voiceless, superficially resembling patients in a vegetative state or akinetic mutism. In acute locked-in syndrome (LIS), eye-coded communication and evaluation of cognitive and emotional functioning is very limited because vigilance is fluctuating and eye movements may be inconsistent, very small, and easily exhausted. It has been shown that more than half of the time it is the family and not the physician who first realized that the patient was aware. Distressingly, recent studies reported that the diagnosis of LIS on average takes over two and half months. In some cases it took four to ...
Diminution of basal ganglia dopaminergic function may play an important role in the generation of akinetic mutism in a patient with anterior cerebral arterial i
Akinetic mutism describes a situation where a patient is alert but unable to move or talk. These symptoms are caused by brain damage.
TY - JOUR. T1 - Bilateral anterior cerebral artery infarction resulting from explosion-type injury to the head and neck. AU - Lipschutz, Joshua H.. AU - Pascuzzi, Robert. AU - Bognanno, James. AU - Putty, Tim. PY - 1991. Y1 - 1991. N2 - A 43-year-old woman suffered a blast-type injury to the head and neck. She subsequently developed bilateral internal carotid artery occlusion and bilateral anterior cerebral artery infarction not demonstrated by magnetic resonance imaging scan 24 hours after the explosion, but confirmed by a second scan 8 days after the explosion. In patients with blast-type injury to the head and neck who develop coma with a nonfocal neurological exam, the possibility of bilateral carotid artery occlusion and bilateral ischemic infarction should be considered.. AB - A 43-year-old woman suffered a blast-type injury to the head and neck. She subsequently developed bilateral internal carotid artery occlusion and bilateral anterior cerebral artery infarction not demonstrated by ...
Introduction. The traditional view of cognition in idiopathic or genetic generalized epilepsy (GGE) is that one size fits all i.e. only very mild generalized impairment might be detected, if any. This paper describes four case studies of cognitive functioning in GGE patients with photosensitivity and reflexive seizures. Aim. The aim was to discover whether each individuals set of cognitive deficits varied in accordance with his/her other clinical phenomena such as photosensitivity and kinds of reflexive seizures. Method. Neurological and cognitive performance was assessed by comprehensive evaluation of each patient based on interviews, neurologists EEG reports and neuropsychological tests. Assessment of cognitive domains included estimated pre-morbid I.Q. based on reading ability and demographic norms, current I.Q., attention factors, verbal memory, visual memory and executive functions. Results. Clinical signs and investigative studies indicated that two cases typically began reflexive ...
The Federation of American Scientists Biosecurity Project has prepared a brief online survey to collect feedback on our Case Studies in Dual-use Biological Research. To thank participants for completing the survey, we will enter them into a drawing for an 8GB iPod nano. Click here to go to the case studies or here to go directly to the survey. The survey is open now through May 31, 2007.. If you have any colleagues, students or friends involved in biological research or biosecurity, please let them know about the Case Studies and the survey. Thank you for your feedback!. The first four case studies include an introduction to biosecurity, the poliovirus synthesis experiments conducted in Eckard Wimmers laboratory at the State University of New York at Stony Brook; the porous particle development work of David Edwards at Harvard University; and the mousepox experiments conducted by two Australian researchers, Ron Jackson and Ian Ramshaw.. We include in-depth interviews with the researchers to ...
Our courses are suitable for Medical professionals and Aesthetic practitioners. NB: We expect the delegates to have read the course materials fully prior to attending the onsite course at the Academy of Advanced Aesthetics. In order to graduate from all of our courses, students will need to pass a final written examination to assess their knowledge and understanding, and to pass a practical observation performing the treatment in full, including client consultation and aftercare. For Level 4 courses, after having completed the practical session at the Academy, students will be asked to complete four case studies and a 5,000-word assignment in order to complete the course. Level 4 Accredited Course certificates will be issued externally. For our Short Courses, we will provide an Academy of Advanced Aesthetics Diploma. Our short courses, for those wish to learn more about the treatments without gaining an accredited Level 4 course, are two days in duration. The HIFU Level 4 accredited course for ...
While conventional wisdom and recently published studies may hold that link building takes a long time to have a positive impact, columnist Conrad Saam begs to differ and shares four case studies.
Hi, yesterday had done echo and pro bnp the results are..... Structural Interpretation Akinetic lateral wall. Severely hypokinetic inferior wall. IVS, anterior wall and LV apex are showing norma...
Selective Mutism is a condition that severely restricts a childs capacity for communicating verbally outside the home and typically occurs at the rate of 1 in every 200 children in primary school and much more frequently in preschool-aged children. It is a treatable anxiety disorder, but generally requires 1 to 2 years of treatment in order to resolve. The transition to school for preschoolers with Selective Mutism is often a stressful and difficult process and raises many questions for caregivers and parents. There are many factors to consider around such a transition such as educating the primary school and teachers about selective mutism, and preparing the child for the transition.. ...
This evening webinar about helping preschoolers with selective mutism transition to school is suitable for parents, educators and support staff who have a child with selective mutism transitioning from preschool to school in the upcoming year.
Research-based treatments found effective for Selective Mutism Some of the following information is excerpted from: Cohan, S.L., Chavira, D.A., and Stein, M.B.
Learn more about Penetrating Brain Injury at Doctors Hospital of Augusta DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
OBJECTIVE The aim of this study is to examine the prevalence of selective mutism (SM) in Kocaeli, Turkey. METHOD Kindergarten, first, second and third grade students of all public/private schools within the city were included in the study. SM screening forms prepared on basis of DSM-IV were submitted to classroom teachers in all these schools asking whether they had any students meeting such symptoms. RESULTS About 84.51% of the schools returned forms covering 64,103 children. Five hundred and twenty six of these children were thought to have symptoms of SM by their teachers. After their DSM-IV based clinical evaluation by a child and adolescent psychiatrist, only 21 children were diagnosed as SM. Among the SM group, three were in the kindergarten, 15 were in the first grade and three were in the second grade. Twelve of the children were male and nine were female (male: female ratio is 1.3:1). In this cross-sectional study, 0.83% of children were reported to have SM symptoms by their teachers.
Treating Selective Mutism is difficult, likely because the behavior is an effective strategy for reducing childrens anxiety feelings.
Belmont Psychological Services is a group of psychotherapists who specialize in the provision of Cognitive Behavioral Therapy (CBT). CBT is a structured and focused style of therapy that provides people with the concrete tools that they need to get better quickly. It is by far the most researched of all the clinical orientations and has been proven to be helpful for a wide variety of mental health problems. BPS is the leading provider of CBT in Long Beach, CA. Our therapists are known in the community for helping patients with complex problems who have failed to make progress in past treatment. We are extremely successful in treating patients who have more complicated problems such as Obsessive Compulsive Disorder and Bipolar Disorder. Our clinicians are also unique in that we are some of the few providers in the area who use CBT with younger children who demonstrate a variety of problems, including selective mutism, school refusal, separation anxiety, and/or phobias.. If you are interested in ...
AFTER two years of silence and close to 100 sessions, Eloise Radosevic spoke her first words to her psychologist. Before that shed pass notes, unable to talk in sessions due to a severe but extremely rare social anxiety condition called selective mutism, which made even simple conversations with her own grandparents difficult.
Dr. Rachel Busman discusses selective mutism disorder, from its prevalence, and how it impacts school and social life, to the most effective treatments.
Dr. Katherine Dahlsgaard discusses the high risk factor of selective mutism in twin siblings, and offers a few methods of specialized treatment. Scientific
This started me thinking of the slow progress Josiah did show, what he was already achieving already. If one is honest he/she must admit dealing with Selective Mutism as a parent is frustrating it takes some time to achieve anything and even then they can regress without warning or any reasons why. This is what lead to our decision, did I want to start medication out of frustration. Secondly for medication to work there must be a strong support base, which in some aspects we didnt have. We were and still are waiting on the results of the funding application the school had made. If were to take a risk and try the medication we want to have everything set in place at this point that isnt the case. I also considered that the impact for Josiah to overcome his fears and the strength of self he would have if he was able to do this on his own. Now dont get me wrong I wouldnt allow him to suffer in his anxiety or flounder, this only works as long as their is small baby steps of progress. So for now ...
Haseki Educational and Research Hospital, Neurosurgery Department İstanbul, Turkey AIM: Cerebellar mutism is a documented complication of posterior fossa surgery in pediatric ages. Risk factors such as the type of tumor, size, and location of tumor, hyrdrocephalus, postoperative cerebellar swelling for cerebellar mutism were investigated in this study.. MATERIAL and METHODS: A consecutive series of 32 children with a cerebellar tumor were operated on at the Haseki Educational and Research Hospital, Department of Neurosurgery, between 1990 and 2005. Their speech and neuroradiological studies were systematically analysed both preoperatively and postoperatively. RESULTS: Cerebellar mutism developed in ten children (32%) in the early postoperative period. The type of tumor, midline localization, and vermian incision were significant single independent risk factors. In addition, an interdependency of possible risk factors (tumor>5 cm, medulloblastoma) was found. The latency for the development of ...
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Sites in this category deal with this psychiatric disorder that is characterized by consistent failure to speak in select social settings in which there is an expectation to speak; such as school.
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So this week I had an experience online on facebook on one of the communities were we were discussing organisation, home routines and how we all cope with the pressures that we face. During the discussion it was revealed how hard it is for us all to cope and how much we need to take a handle on our lives to make things easier, less stressful and much easier to run. One of my weird passions is organisation, not in the sense that I have my house clean or that everything is run perfectly. But in the sense of my life I try to keep things under control by using the tools that we have online and using our technology such as our phones and ...
Arsenic is a non-essential element that poses risks in many environments, including soil, groundwater, and surface water. Insights into the environmental biogeochemistry of As can be gained by comparing As and P reaction processes. Arsenic and P are chemical analogues, and it is proposed that they have similar chemical behaviors in environmental systems. However some chemical properties of As and P are distinct, such as redox reactions, causing the biogeochemical behavior of the two elements to differ. In the environment, As occurs as either As(V) or As(III) oxyanions (e.g., AsO43− or AsO33−). In contrast, P occurs predominantly as oxidation state five plus; most commonly as the orthophosphate ion (PO43−). In this paper, data from four published case studies are presented with a focus on P and As distribution and speciation in soil. The goal is show how analyzing P chemistry in soils can provide greater insights into As reaction processes in soils. The case studies discussed include: (1) soil
The application of twin screw extrusion (TSE) as a scalable and green process for the manufacture of cocrystals was investigated. Four model cocrystal forming systems, Caffeine-Oxalic acid, Nicotinamide-trans cinnamic acid, Carbamazepine-Saccharin, and Theophylline-Citric acid, were selected for the study. The parameters of the extrusion process that influenced cocrystal formation were examined. TSE was found to be an effective method to make cocrystals for all four systems studied. It was demonstrated that temperature and extent of mixing in the extruder were the primary process parameters that influenced extent of conversion to the cocrystal in neat TSE experiments. In addition to neat extrusion, liquid-assisted TSE was also demonstrated for the first time as a viable process for making cocrystals. Notably, the use of catalytic amount of benign solvents led to a lowering of processing temperatures required to form the cocrystal in the extruder. TSE should be considered as an efficient, scalable, and
Selective mutism is different from being shy. And the inability to speak is not the same (but can co-occur with) social anxiety disorder.
Dr. Lake & Associates offers neuropsychological testing, gifted testing, individual therapy, parent coaching, consultation, and groups. We treat mood disorders, anxiety, ADHD, employment stress, OCD, behavioral problems, Autism (ASD), grief, depression, selective mutism, twice-exceptional 2e.
This report raises the issue of a patient who, despite the preservation of intraoperative mMEPs, emerged from anaesthesia with hemiplegia and mutism. Unexpected postoperative neurological deficits are traumatic to both patients, their family, and the surgical team. In this setting, the ability to predict outcome significantly contributes to the clinical management of these patients. Whenever neuroimaging studies are not conclusive, functional-rather than morphological-evaluation of the integrity of M1/CST using neurophysiological tests could be useful.. Zentner et al 8 described 13 patients who had resective procedures involving the SMA. Despite preservation of mMEPs at the end of surgery in all of them, five patients emerged from anaesthesia with a typical SMA syndrome including hemiplegia contralateral to the resection side. Elicitability of mMEPs was tested early postoperatively using the single magnetic stimulus technique, but mMEPs were not present in the immediate postoperative period and ...
Another word for muteness. Find more ways to say muteness, along with related words, antonyms and. Muteness or mutism (from Latin mutus silent) is defined as an absence of speech while
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There is no way back to the Garden of Eden, back to nature, and no chance of becoming the gods we appear to think we are now. We neither would want to overcome nature nor would we want to go back to nature. There is at least one more option: to find balance with nature. This could be a sensible, alternate path to the future and a goal to be reached with all deliberate speed for the sake of the children. After all, we are borrowing this world from our children. Surely we will not continue mortgaging the childrens future and ruining the planet all of us inhabit here now to the point Earth cannot be fruitfully inhabited by them and coming generations. Certainly not on our watch!. Responsible people will have to stop colluding in elective mutism and ignoring the best available scientific evidence of human population dynamics and human overpopulation of the Earth. The time remaining for us elders to secure a good enough future for the children is fairly short, I suppose. We cannot effectively ...
Climate change is causing growing variability and uncertainty in rainfall in Africa. Since the continents food production systems are dominantly rain-fed, these changes are putting food security at even higher risk. In order to reduce this dependency, institutional reforms in the agricultural water sectors have become a priority in research and policy.. In this report, Atakilte Beyene, senior researcher at the Nordic Africa Institute, together with twelve researchers based in Africa, studies current agricultural water reforms in Kenya, Tanzania, Uganda, and other East African countries. The report consists of four case studies and an introductory section. The first case study evaluates the performance of community participation in water resources governance in the Mount Kenya Region. It uncovers the implication of a ban on traditional institutions on water security at a catchment level. The second case analyses the prospects of introducing pro-poor water schemes in conditions where climate ...
Our latest JWMM paper by Masson (Centre de Recherche et de Développement en Science du Sol, Economie, Environnement, Aménagement), Lefer (Université du Littoral-Côte-dOpale), Boulemia (Université dArtois), and Naji (University of Lille Nord de France) is now out. Read more about representing drainage porosity as a function of constant loss and initial runoff time with applications in four case studies.
This book addresses the history of interaction in the Aegean world during the third century BC. The main focus is the island of Delos and its important regional sanctuary. Through a thorough investigation of the Delian epigraphic and material evidence, it explores how and to which degree the islands of the southern Aegean formed active networks of political, religious, and cultural interaction. The book aims to show that this kind of regional interaction in the southern Aegean resulted in the creation of a regional identity, which was expressed, among other things, in the existence of a federal union of the islands, the so-called Islanders League. It is structured along the lines of four case studies which explore different types of networks around Delos: the federal organization of islands (Islanders League), the participation of Delian and other agents in the processes of monumentalization of the Delian landscape, the network of honours, and the social dynamics of dedication through the record of
The purpose of the session was to better understand governance challenges related to forest landscape restoration (FLR) implementation, and options to address these. The session was organised as follows: Stephanie Mansourian introduced the subject of governance and FLR. She was followed by four case study presentations: Nadine Crookes from Parks Canada, John Crockett from the US Forest Service, Gérard Rambeloarisoa from the Madagascar Biodiversity Fund and Chris Buss from IUCN, and then 20 minutes of questions and discussion. A total of 30-40 participants attended the one hour session. Read more…. ...
(1998) Backer, Rogers. Journal of Health Communication. Four case studies of the adoption of work-site AIDS programs are investigated, two of which were modifications of the Centers for Disease Control and Preventions Business Responds to AIDS (BRTA) p...
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders. (4th ed., text rev.). Washington, DC: Author. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author. American Speech-Language-Hearing Association. (2016). Code of ethics [Ethics]. Available from www.asha.org/policy/. Anstendig, K. D. (1999). Is selective mutism an anxiety disorder? Rethinking its DSM-IV classification. Journal of Anxiety Disorders, 13, 417-434. Beidel, D. C., & Turner, S. M. (2007). Shy children, phobic adults. Nature and treatment of social anxiety disorder (2nd ed.). Washington, DC: American Psychological Association. Beidel, D. C., Turner, S. M., & Morris, T. M. (1999). Psychopathology of childhood social phobia. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 643-650. Bergman, R., Piacentini, J., & McCracken, J. (2002). Prevalence and description of selective mutism in a ...
Define Extrapyramidal syndrome. Extrapyramidal syndrome synonyms, Extrapyramidal syndrome pronunciation, Extrapyramidal syndrome translation, English dictionary definition of Extrapyramidal syndrome. abbreviation for earnings per share
Selective Mutism Therapy and Counseling at the Cognitive Behavior Therapy Center. San Jose, Saratoga, Los Gatos, Cupertino, Campbell, Monte Sereno, Sunnyvale,
Autism is a developmental disorder that causes a child to have impairments in communication. Children with autism may have a delay in (or complete lack of) the development of spoken language. The most obvious signs of autism are usually noticed between 2 and 3 years of age. Although many children on the spectrum do speak, they may use language in unusual ways, avoid eye contact, and prefer to be alone. Autism may first be noticed by school professionals, who become aware that the child is not interacting socially with his peers in an appropriate way.. Other Possibilities:. Selective Mutism:. Selective mutism is an anxiety disorder in which children do not speak in particular social situations. Many children with selective mutism are talkative at home, but there may be a complete lack of speech in other settings, such as in school. They may not communicate with peers or teachers at all, which can lead to school professionals being concerned about their social development. These social ...
Penetrating traumatic brain injury (pTBI) has been difficult to model in small laboratory animals, such as rats or mice. Previously, we have established a non-fatal, rat model for pTBI using a modified air-rifle that accelerates a pellet, which hits a small probe that then penetrates the experimental animals brain. Knockout and transgenic strains of mice offer attractive tools to study biological reactions induced by TBI. Hence, in the present study, we adapted and modified our model to be used with mice. The technical characterization of the impact device included depth and speed of impact, as well as dimensions of the temporary cavity formed in a brain surrogate material after impact. Biologically, we have focused on three distinct levels of severity (mild, moderate, and severe), and characterized the acute phase response to injury in terms of tissue destruction, neural degeneration, and gliosis. Functional outcome was assessed by measuring bodyweight and motor performance on rotarod. The results
The shooter was identified as 23-year-old Seung-Hui Cho, a senior at Virginia Tech. He was a South Korean citizen with U.S. permanent resident status who was majoring in English. The Virginia Tech Review Panels August 2007 report (Massengill Report) devoted more than 20 pages to Chos troubled history.[3]:21[83]:31-53 At three years of age, Cho was described as shy, frail, and wary of physical contact.[84] In eighth grade, Cho was diagnosed with severe depression as well as selective mutism, an anxiety disorder that inhibited him from speaking in certain situations and/or to specific people.[85][86] While early media reports carried reports by South Korean relatives that Cho had autism,[87][88] the Massengill Report stated that the relationship between selective mutism and autism was unclear.[83]:34-35 Chos family sought therapy for him, and he received help periodically throughout middle school and high school.[83]:34-39 Early reports also indicated Cho was bullied for speech difficulties ...
Creutzfeldt-Jacob disease should be considered in the setting of a rapidly progressive dementia with psychiatric symptoms, ataxia, mutism, myoclonus, and pyramidal or extrapyramidal signs. 1
Dear Editor,. Cognitive disorders and depression are intensely correlated, not only by sharing risk factors, but also by frequently showing similar presentations. This might lead to challenging cases among the elderly population, since, in old age, depression commonly manifests with prominent neurovegetative and cognitive symptoms1. Here we report the case of a patient who had been treated, but after clinical evaluation demonstrated to be a case of sporadic Creutzfeldt-Jakob disease (sCJD), a rare and fatal neurodegenerative condition.. A 77 year-old female, without relevant psychiatric or medical history. Six months before admission, she presented with increasingly irritability and sadness. Within days, clinical condition declined, progressing to mutism, lack of interaction, anorexia, immobility and was treated with different combinations of antidepressants and antipsychotics, with the hypothesis of major depression. She was then referred to the Psychiatry inpatient unit of the local University ...
The Childhood Mental Disorders and Illnesses topic center provides an overview of mental and emotional disorders and illnesses impacting children and their families including attention deficit hyperactivity (ADHD), mental retardation, autism and other pervasive development disorders, and disorders of learning, speech and communication, movement, motor function, feeding, conduct, elimination, and anxiety (such as selective mutism and separation anxiety).
The Childhood Mental Disorders and Illnesses topic center provides an overview of mental and emotional disorders and illnesses impacting children and their families including attention deficit hyperactivity (ADHD), mental retardation, autism and other pervasive development disorders, and disorders of learning, speech and communication, movement, motor function, feeding, conduct, elimination, and anxiety (such as selective mutism and separation anxiety).
The Childhood Mental Disorders and Illnesses topic center provides an overview of mental and emotional disorders and illnesses impacting children and their families including attention deficit hyperactivity (ADHD), mental retardation, autism and other pervasive development disorders, and disorders of learning, speech and communication, movement, motor function, feeding, conduct, elimination, and anxiety (such as selective mutism and separation anxiety).
I am checking as the mom much farther down the road to be a help, if I can. My daughter was diagnosed in November 2012. This is our five year anniversary with this disease and there is HOPE for all of your kids. This is long but please read: With one of the most profound and difficult to treat cases to ever treat - my daughter is staring community college in the spring! You name the symptom and she has exhibited it - to name a few... complex tics, anorexia, bed wetting, mutism, depression, OCD, sleep disorders, a host of psychiatric symptoms (including schizoprhenic type symptoms including violence), and catatonia. She has also had every treatment - countless antibiotics, IVIVGs, rituximab, cell cept, prophylactic antibiotix, cytoxan, tociluzimab. We lost four years of life - she lost high school, and I shut down ever yaspect of life to take care of her. It has been lonely, frustrating, difficult, depressing...and yet hopeful, strengthening, funny, and finally TRIUMPHANT. I am repositing ...
Case 1 A 67 year-old woman with a history of HTN presented to the ED after being found at work not moving her right side. Exam shows mutism, R face and arm plegia with decreased sensation in R arm as well as L gaze deviation and R homonymous hemianopsia. Her symptoms began at noon, it is now 4:30 p.m. There are no contraindications to tPA.
I dont know, I was initially diagnosed with selective mutism when I was a kid which was heavily linked with social anxiety. I was aspie as well but didnt get diagnosed until I was 18. I did have social anxiety as well or im pretty sure I did. Cause attempting to intiate a conversation or talk to someone was very hard. It terrified me. That psych I saw for 3 years when I was young didnt realize anything. I dont know if it was because I was female. I was guessing because aspergers was less known about back then.. ...
V tokratni 7. ediciji mini festivala Metaljot Raspaljot gostimo žanrsko zelo pester nabor bandov. The Canyon Observer pri nas veljajo za prvake atmosferičnega sludge, noise, post-rock/metala, kjer lahko pričakujemo nič drugega kot audio-vizualno poslastico, vse ostale besede bi bile povsem odveč.. Pravtako, kot The Canyon Observer iz Ljubljane prihaja stoner, progressive, metal jam trio Jegulja, ki že lep čas navdušujejo na domačih in tujih odrih. Če ste ljubitelji progresivnega in alternativnega metala (sebi pravijo, da igrajo dentist metal) tipa Mastodon, Deftones, Tool in The Dillinger Escape plan vam bodo zagotovo všeč tudi kranjski Amalgam, ki ga sestavljajo člani skupin Armaroth, Raggalution, Didge in Mutism. Iz Prekmurja, natančneje iz Lendave nam po sveže izdanem albumu prihajajo Inhibis, ki igrajo mešanico alternative, post-stoner rocka in metala. Za odmik iz realnosti pa bo poskrebel Dejan Požegar (Nakajima, Wreck), ki stoji za umetniškim imenom Neo-Cymex, kateri ...
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Interest areas: attachment; bereavement; domestic abuse; working with hard to reach/engage families - systemic and community based work; parenting groups; schools as systems - eg research and revising policies; staff support and stress; eliciting the voice of the child and involving the child in decisions; therapeutic work eg narrative therapy, therapeutic stories, PCP, CBT; group work; selective mutism; identity of PMLD children ...
I was 9-11 years old when I progressively went from 90% meaning deaf and predominantly stored phrases, TV scripts and echolalia to being only 50% meaning deaf and finally striving to string simple novel sentences together. By age 11 I could construct slow, klunky simple sentences (and still also had fluent, expressive echolalia), by age 12 I could do long litanies at people and was developing simple conversing skills. By 18 I had learned to suppress much of my echolalia, keeping my self chatter for when I was alone. So how did this happen?. Around age 9-11 my father left a record player and a pile of old 78 records in my room featuring a vast array of theatrical songs from the 1920s-1940s and I came to sing in a vast array of voices with far expanded, albeit echolalic, vocabulary. This also greatly improved my confidence with verbal speech and my enjoyment of it and countered many an episode of Selective Mutism as I progressively moved into functional speech.. Around age 9-10 I was also left a ...
Tinley 1979:33). The Pilanesberg was to be different and the aim was to reflect a new vision of conservation practice in Africa.. Not only did they introduce the radical idea of using national parks sustainably as engines of regional development sensitive to local community needs, Van Riet and Tinley also introduced a novel concept of planning and design (Farrell et al. 1978). After surveying the geomorphology and other aspects of the landscape, habitats and vegetation cover, their report proposed that in order to maximise wildlife viewing in the small area and utilise it to the best advantage, all major tourism facilities should be located on the boundaries of the park, thus preserving the interior of the crater from unsightly camps, restaurants and other amenities. This peripheral development was different from other national parks and game reserves which had normally sited major visitor accommodation within the protected area itself. Moreover, using the internal watersheds as ecological ...
Through four case studies in Lebanon, Jordan, Kenya, and Ethiopia, the project will demonstrate the value of local knowledge ecosystems in promoting a more nuanced and localized understanding of how refugees, host communities, states, and development actors in the Global South can deal more effectively with the challenge of forced displacement ...
Through four case studies in Lebanon, Jordan, Kenya, and Ethiopia, the project will demonstrate the value of local knowledge ecosystems in promoting a more nuanced and localized understanding of how refugees, host communities, states, and development actors in the Global South can deal more effectively with the challenge of forced displacement ...
도서관에서 가져오기! Basics of genealogy reference : a librarians guide. [Jack Simpson] -- This book offers novice and experienced reference librarians an introduction to tried-and-true genealogy techniques and resources. With the help of four case studies, Simpson outlines a basic ...
Parkinsons Disease: Epidemiology, Causes, Features, Diagnosis and Management Akinetic Rigid Syndrome or Idiopathic Parkinson Disease-Are a number of
The symptoms of congenital heart failure are addressed in this surgical procedure for mounting a patch in the ventricle of the heart to reduce ventricular volume. Placement of the patch is facilitated by palpating a beating heart to identify akinetic, although normal appearing, tissue. An apical patch having an oval configuration facilitates return of the heart to a normal apical shape which enhances muscle fiber efficiency and a normal writhing pumping action. An inferior patch having a triangular configuration can also be used. The patches include a semi-rigid ring, and a circumferential rim to address bleeding. Patch placement is further enhanced by creating a Fontan-type neck and use of pledged sutures. Intraoperative vascularization and valve replacement is easily accommodated. Increased injection fraction, reduced muscle stress, improved myocardial protection, and ease of accurate patch placement are all achieved with this procedure.
A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge.
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
This mutation was identified in a Korean woman with AD and a family history of the disease (Kim et al., 2020). Her symptoms, starting at age 40, included memory impairment, visuospatial dysfunction, abulia, apathy, and depression. Moreover, shortly prior to death and three years after disease onset, the patient developed myoclonus and seizures. Her APOE genotype was APOE3/APOE3.. This variant was not found in the gnomAD database, nor in 500 Korean controls.. Neuropathology ...
Akinetic mutism Hyperkinesia "Bradykinesia". B. Kolb, I. Whishaw (2011). An Introduction to Brain and Behavior. p. 373. Ling, ...
Johnson, John (1984). "Stupor and akinetic mutism". Contemporary Neurology. pp. 96-102. doi:10.1016/B978-0-407-00308-8.50018-5 ... featuring the curious symptom of waxy flexibility and the state produced by the drug has been compared to Akinetic mutism. The ...
Akinetic mutism has been associated with structural damage in a variety of brain areas. Akinetic mutism and catatonia may both ... Akinetic mutism: Akinetic mutism is a neurological disorder characterized by a decrease in goal-directed behavior and ... Akinetic mutism Autistic catatonia Awakenings (1990 biopic about catatonic patients, based on Oliver Sacks's book of the same ... Differentiating both disorders is the fact that akinetic mutism does not present with echolalia, echopraxia, or posturing. ...
Aboulia Akinetic mutism Athymhormia Huntington's disease Progressive supranuclear palsy Laplane, D.; Dubois, B. (2001). "Auto‐ ...
The conditions of akinetic mutism and negative symptoms are closely related. In akinetic mutism, a stroke or other lesion to ... the anterior cingulate cortex causes reduction in movement (akinetic) and speech (mutism). Anhedonia occurs in roughly 70% of ...
Anterior corpus callosum lesions may result in akinetic mutism or anomic aphasia. See also: Alien hand syndrome Dyslexia ...
In severe cases, patients may enter a coma-like state (akinetic mutism).[citation needed] Patients may also experience abnormal ...
Most experts agreed that abulia is clinically distinct from depression, akinetic mutism, and alexithymia. However, only 32% ... akinetic mutism. It is well documented that the caudate nucleus is involved in degenerative diseases of the central nervous ... and one could easily see an extreme case of abulia as akinetic mutism or a lesser case of abulia as apathy and therefore, not ... with apathy being less extreme and akinetic mutism being more extreme than abulia. The condition was originally considered to ...
Akinetic mutism is a state in which the individual is unable to speak or move.[10] ... "Definition of Akinetic mutism". Archived from the original on 2014-12-26.. ... Selective mutism previously known as "elective mutism" is an anxiety disorder very common among young children, characterized ... Muteness or mutism (from Latin mutus, meaning 'silent') is an inability to speak, often caused by a speech disorder or surgery ...
Dubois, Borz and his men invade the apartment of Bernard Hersch, who is suffering from akinetic mutism. There, Dubois ...
The final or terminal stage is characterized by stretching spasms, akinetic mutism, hypotonic paresis, central pyrexia, and ...
Myoclonus persists "even in the late stages of the disease" and even "when patients are unconscious". Akinetic mutism were ...
A rare cause of mutism is akinetic mutism which results due to a lesion around the third ventricle of the brain. Apperception ... Aphemia is the alternate term for mutism. Mutism is absence of speech with apparently normal level of consciousness. Mutism can ... mutism, echolalia (imitating speech), or echopraxia (imitating movements). There is a catatonic subtype of schizophrenia. Cerea ...
Bilateral ischemia of the area supplied by the paramedian artery can cause serious problems including akinetic mutism, and be ...
If a person can demonstrate ability in voluntary usage of limbs, catatonia and akinetic mutism are most likely ruled out from ... Patients with catatonia or akinetic mutism are not able to perform voluntary commands that involve the use of limbs, while ... In determining a diagnosis between with catatonia, akinetic mutism, and FCMS, a person must demonstrate their ability to ... FCMS shares similar characteristics with the following disorders: catatonia, akinetic mutism, orobuccal apraxia, Broca's ...
Audrey's family contended that she was in a state called akinetic mutism - unable to speak and with limited movement, but fully ...
... and akinetic mutism. There is evidence that damage to ACC is present in patients with schizophrenia, where studies have shown ...
Differential brain imaging of patients with such global disturbances of consciousness (including akinetic mutism) reveal that ...
... akinetic mutism, general retardation "frontal release" signs, i.e. reappearance of primitive reflexes such as the snout reflex ...
... akinetic mutism MeSH C10.228.140.055 - amblyopia MeSH C10.228.140.060 - amnesia, transient global MeSH C10.228.140.068 - ... mutism MeSH C10.597.606.150.500.800.750 - stuttering MeSH C10.597.606.150.550 - learning disorders MeSH C10.597.606.150.550.200 ...
Frontal abulic syndrome Loss of initiative, creativity and curiosity Pervasive emotional apathy and blandness Akinetic mutism ... "Mutism in the Older Adult". Schott, J. M.; Rossor, M. N. (2003-05-01). "The grasp and other primitive reflexes". Journal of ... With more severe impairment there may be echolalia or mutism. Neurological examination may show primitive reflexes (also known ...
Akinetic mutism List of people with locked-in syndrome The Diving Bell and the Butterfly: memoirs of journalist Jean-Dominique ...
... akinetic mutism, slowness and lack of spontaneity Urinary incontinence which usually occurs with bilateral damage in the acute ...
... is a medical term describing patients tending neither to move (akinesia) nor speak (mutism). Akinetic mutism ... Akinetic mutism can also occur as a result of damage to the mesencephalic region of the brain. Mesencephalic akinetic mutism is ... However, akinetic mutism most often appears in two different forms: frontal and mesencephalic. Akinetic mutism can occur in the ... When the anterior cingulate cortex is damaged, it can result in akinetic mutism. Akinetic mutism is a symptom during the final ...
Akinetic mutism. *Autistic catatonia. *Awakenings (1990 biopic about catatonic patients, based on Oliver Sacks' book of the ... mutism), as well as waxy flexibility, in which they maintain positions after being placed in them by someone else. Mutism may ... mutism (i.e., no, or very little, verbal response [exclude if known aphasia]) ...
Lesions in this area can lead to low drive states such as apathy, abulia or akinetic mutism and may also result in low drive ...
The conditions of akinetic mutism and negative symptoms are closely related. In akinetic mutism, a stroke or other lesion to ... the anterior cingulate cortex causes reduction in movement (akinetic) and speech (mutism). [11] ...
Akinetic mutism is a medical term describing patients tending neither to move (akinesia) nor speak (mutism). Akinetic mutism ... Akinetic mutism can also occur as a result of damage to the mesencephalic region of the brain. Mesencephalic akinetic mutism is ... However, akinetic mutism most often appears in two different forms: frontal and mesencephalic. Akinetic mutism can occur in the ... When the anterior cingulate cortex is damaged, it can result in akinetic mutism. Akinetic mutism is a symptom during the final ...
Locked in syndrome, from stroke, TBI, ALS, encephalitis, or just intubation with paralysis or limb trauma was always a communication challenge. Now, after having it myself for a few days from an
Akinetic Mutism. Known as: mutism akinetic, Akinetic Mutism [Disease/Finding], Mutism, Akinetic (More). ... OKT3 neurotoxicity presenting as akinetic mutism.. *Sean Joseph Pittock, Alejandro A Rabinstein, Brooks Sayre Edwards, Eelco F ... Akinetic mutism with bithalamic infarction. Neurophysiological correlates. *Peter Hmf van Domburg, Hans J. ten Donkelaar, ... Cyclosporin-associated akinetic mutism and extrapyramidal syndrome after liver transplantation.. *GeorgeL. A. Bird, J. Meadows ...
Akinetic mutism information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, ... Contents for Akinetic mutism: *Akinetic mutism *What is Akinetic mutism? *Videos related to Akinetic mutism *Types of Akinetic ... Symptoms of Akinetic mutism *Diagnostic Tests for Akinetic mutism *Home Testing and Akinetic mutism *Signs of Akinetic mutism * ... Forum Discussions about Akinetic mutism. *Reason for Mutism?. More information about Akinetic mutism. *Akinetic mutism: ...
Akinetic mutism describes a situation where a patient is alert but unable to move or talk. These symptoms are caused by brain ... Hyperpathic akinetic mutism: When the frontal lobe is involved, the akinetic mutism is known as hyperpathic akinetic mutism.* ... Somnolent akinetic mutism: When the mesencephalic region is damaged, the condition is called somnolent akinetic mutism. ... Akinetic mutism: Description, Causes and Risk Factors:. Subacute or chronic state of altered consciousness, in which the ...
At the age of 34, he became akinetic mutism after n. By admin April 25, 2019 Uncategorized 0 Comments ... HomeUncategorizedAt the age of 34, he became akinetic mutism after n ...
title = "Episodically remitting akinetic mutism following subarachnoid hemorrhage",. abstract = "Akinetic mutism is ... Episodically remitting akinetic mutism following subarachnoid hemorrhage. Together they form a unique fingerprint. * Akinetic ... Akinetic mutism is characterized by alertness with near complete absence of volitional activity. The authors report a case of ... N2 - Akinetic mutism is characterized by alertness with near complete absence of volitional activity. The authors report a case ...
Akinetic mutism. AND the absence of a positive result for any of the four tests above that would classify a case as "probable" ...
This case series demonstrates that catatonia, which is often treatable, may be underdiagnosed in acute medical settings due to low awareness of the condition among both generalists and psychiatrists.
Related to abulia: akinetic mutism. a·bu·li·a. also a·bou·li·a (ə-bo͞o′lē-ə, -byo͞o′-). n.. Loss or impairment of the ability ... Disorders of diminished motivation (DDM)--including apathy, abulia, and akinetic mutism--are characterized by impairment in ...
Akinetic Mutism. Disease. Disease Susceptibility. Autistic Disorder. Autism Spectrum Disorder. Child Development Disorders, ... Autism Autism Spectrum Disorder Autistic Disorder Autism, Akinetic Autism; Atypical Autism; Psychopathy Autism Fragile Syndrome ...
Akinetic Mutism. *Device: stimulation device. Interventional. Not Applicable. *Hospices Civils de Lyon ...
Akinetic Mutism. A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved ...
Akinetic Mutism. AM is a condition characterized by diminished neurologic drive with a decrease in nearly all motor functions ... N. Nagaratnam, K. Nagaratnam, K. Ng, and P. Diu, "Akinetic mutism following stroke," Journal of Clinical Neuroscience, vol. 11 ... B. C. Yarns and D. K. Quinn, "Telephone effect in akinetic mutism from traumatic brain injury," Psychosomatics, vol. 54, no. 6 ... akinetic mutism (AM), and spinal cord injury (SCI) can also have very similar presentation making differential diagnosis ...
... mutism, negativism, posturing, mannerisms, agitation, stereotypy, grimacing, echolalia, or echopraxia (Table 1) [2].. Table 1 ...
Akinetic mutism induced by tacrolimus.. Sierra-Hidalgo F, Martínez-Salio A, Moreno-García S, de Pablo-Fernández E, Correas- ...
akinetic mutism, 10. Alabama, DNR guidelines in, 118. alliances in right to die cases, 175-176. ...
D Akinetic mutism. III Typical EEG 2 ACCIDENTALLY TRANSMITTED (IATROGENIC) TSE. 2.1 Definite Definite TSE with a recognised ...
Akinetic mutism Hyperkinesia "Bradykinesia". B. Kolb, I. Whishaw (2011). An Introduction to Brain and Behavior. p. 373. Ling, ...
"Definition of Akinetic mutism". Archived from the original on 2014-12-26.. Cite uses deprecated parameter ,deadurl=. (help). ... Akinetic mutism is a state in which the individual is unable to speak or move.[10] ... Selective mutism previously known as "elective mutism" is an anxiety disorder very common among young children, characterized ... Muteness or mutism (from Latin mutus, meaning silent) is an inability to speak, often caused by a speech disorder or surgery ...
akinetic mutism silent, alert-appearing. no mental activity.. Loss of frontal lobes and hypothalamus ...
Akinetic mutism and. · A typical EEG, whatever the clinical duration of the disease, and/or. · A positive 14-3-3 assay for CSF ... Akinetic mutism. The suspicion of nvCJD for surveillance purposes is strengthened by the following: · No history of potential ... akinetic mutism. (b) Probable CJD:. (in the absence of an alternative diagnosis from routine investigation) · Progressive ...
akinetic mutism. *coma vigilans. - elite association - COSMIC cancer census association via MalaCards ...
Akinetic mutism.. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the ...
Akinetic Mutism. The last syndrome that this section will discuss is called akinetic mutism, which can best be described as a ... Patients with akinetic mutism, although they are awake, alert and conscious, simply do nothing. Their eyes track moving objects ...
akinetic mutism. *coma vigilans. ceroid lipofuscinosis, neuronal, 11. *neuronal ceroid lipofuscinosis 11 ...
In April 1995, she developed generalized myoclonic jerks and akinetic mutism. An electroencephalograph showed a 6- to 10-Hz ...
This patient followed an atypical clinical course: 16 months had passed before she developed akinetic mutism, and periodic ... sharp waves had not been detected on EEG after 2 years in spite of her akinetic mutism. Brain biopsy showed primary spongiform ...
Tremor, akinetic mutism. HTN. Nephrotoxic gout, hyperK 29 Azathioprine mech & SE Inhibits purine synthesis. Diarrhea. ...
  • Other causes of akinetic mutism are as follows: Respiratory arrest and cerebral hypoxia Acute cases of encephalitis lethargica Meningitis Hydrocephalus Trauma Tumors Aneurysms Olfactory groove meningioma Cyst in third ventricle Toxical lesions and infections of central nervous system Delayed post-hypoxic leukoencephalopathy (DPHL) Creutzfeldt-Jakob disease (mesencephalic form) Akinetic mutism can be misdiagnosed as depression, delirium, or locked-in syndrome, all of which are common following a stroke. (wikipedia.org)
  • Similarly to akinetic mutism, patients with locked-in syndrome experience paralysis and can only communicate with their eyes. (wikipedia.org)
  • The diagnosis is important as akinetic mutism is often misdiagnosed as depression, delirium and locked-in-syndrome. (medigoo.com)
  • Locked-in syndrome (LIS) is a rare diagnosis in which patients present with quadriplegia, lower cranial nerve paralysis, and mutism. (hindawi.com)
  • Persons with locked-in syndrome (LIS), akinetic mutism (AM), and spinal cord injury (SCI) can also have very similar presentation making differential diagnosis complex. (hindawi.com)
  • This non-sentient state must be distinguished from other conditions of wakeful, reduced responsiveness--such as the locked-in syndrome, akinetic mutism and total global aphasia. (tbims.org)
  • All patients succumbed in a state of akinetic mutism and myoclonus. (bmj.com)
  • myoclonus, visual or cerebellar signs, pyramidal/extrapyramidalsigns or akinetic mutism. (vegsource.com)
  • Diagnostic criteria for sporadic CJD require electroencephalography findings of periodic sharp wave complexes, the presence of 14-3-3 protein, or cortical ribboning on magnetic resonance imaging plus clinical features, rapidly progressive dementia, and at least 2 of the following symptoms: myoclonus, visual or cerebellar dysfunction, pyramidal/extrapyramidal features, and akinetic mutism. (jaoa.org)
  • Many cases of akinetic mutism occur after a thalamic stroke. (wikipedia.org)
  • Akinetic mutism is characterized by alertness with near complete absence of volitional activity. (elsevier.com)
  • Disorders of diminished motivation (DDM)--including apathy, abulia , and akinetic mutism--are characterized by impairment in goal-directed behavior, thought, and emotion. (thefreedictionary.com)
  • Por otra parte, las emociones negativas, por lo general son motivo para caer en la tristeza, desesperanza, falta de deseos por obtener mejores logros, por realizar lo mejor posible sus actividades por interesantes y placenteras que sean, lo se ha denominado abulia o en algunos casos, melancolia, terminos hoy en desuso por la falta de evidencias cientificas. (thefreedictionary.com)
  • Abulia falls in the middle of the spectrum of diminished motivation, with apathy being less extreme and akinetic mutism being more extreme than abulia. (wikipedia.org)
  • Most experts agreed that abulia is clinically distinct from depression, akinetic mutism, and alexithymia . (wikipedia.org)
  • This is known as abulia or akinetic mutism in extreme cases. (verywellhealth.com)
  • due to lesions of various cerebral structures.Akinetic mutism describes a situation where a patient is alert but unable to move or talk. (medigoo.com)
  • Various brain lesions can induce akinetic mutism. (koreamed.org)
  • Here, we study focal brain lesions that disrupt volition, causing akinetic mutism ( n = 28), or disrupt agency, causing alien limb syndrome ( n = 50), to better localize these processes in the human brain. (pnas.org)
  • Akinetic mutism can occur in the frontal region of the brain and occurs because of bilateral frontal lobe damage. (wikipedia.org)
  • Lack of motor function (but not paralysis) Lack of speech Apathy Slowness Disinhibition Akinetic mutism can be caused by a variety of things. (wikipedia.org)
  • Patients with depression can experience apathy, slurring of speech, and body movements similar to akinetic mutism. (wikipedia.org)
  • More severe than apathy but less severe then akinetic mutism. (flashcardmachine.com)
  • In April 1995, she developed generalized myoclonic jerks and akinetic mutism. (cdc.gov)
  • Symptoms first became apparent at age 32 and later manifestations included generalized seizures, akinetic mutism, and frequent myoclonic jerks. (alzforum.org)
  • Akinetic mutism is a medical term describing patients tending neither to move (akinesia) nor speak (mutism). (wikipedia.org)
  • Another cause of both akinesia and mutism is ablation of the cingulate gyrus. (wikipedia.org)
  • Curran and Lang ( 26 ) placed akinetic mutism at the extreme end of the hydrocephalus-parkinsonian spectrum identifying the pathogenetic mechanism in a combination of severe bradykinesia/akinesia plus compromise of the ascending reticular activating system, such as the monoaminergic projection fibers from the brainstem in regions adjacent to the third ventricle that may be impaired when rapid ventricle dilatation occurs. (ispn.guide)
  • Treatments using intravenous magnesium sulfate have shown to reduce the symptoms of akinetic mutism. (wikipedia.org)
  • As seen in the case of Elsie Nicks, the puncture or removal of a cyst causing akinetic mutism can relieve symptoms almost immediately. (wikipedia.org)
  • Symptoms of akinetic mutism suggest a possible presynaptic deficit in the nigrostriatal pathway, which transmits dopamine. (wikipedia.org)
  • The clinical symptoms and neuropathological findings of three patients suffering from akinetic mutism were summarized. (semanticscholar.org)
  • More detailed information about the symptoms , causes , and treatments of Akinetic mutism is available below. (rightdiagnosis.com)
  • A patient with akinetic mutism shows symptoms that are similar to other recognized conditions, such as catatonia in psychiatric patients and locked-in state in paralysis patients, but it is a distinct medical condition.The case study of a 53-year-old male patient who developed akinetic mutism for a period of 7 months after a subarachnoid hemorrhage. (medigoo.com)
  • Other symptoms may be secondary to damage of the nigro-striatal dopaminergic pathway, such as blepharoclonus ( 39 ), inappropriate brief rhythmic contractions of the orbicularis oculi, and akinetic mutism. (ispn.guide)
  • 1 The patient exhibited cortical ribboning, dementia, akinetic mutism, and hyperreflexia, which led to the diagnosis. (jaoa.org)
  • Dr. Darby and team used a cutting-edge neuroimaging technique called lesion network mapping to study the brains of people with two neurological conditions: akinetic mutism and alien limb syndrome. (medicalnewstoday.com)
  • Akinetic mutism with bithalamic infarction. (semanticscholar.org)
  • This is a descriptive study of eight selected patients with akinetic mutism following infarction/hemorrhage in different regions of the brain with characteristic syndromes. (medigoo.com)
  • We attended a 71-year-old woman who presented with akinetic mutism caused by bilateral anterior cerebral artery infarction. (koreamed.org)
  • Selective mutism previously known as "elective mutism" is an anxiety disorder very common among young children, characterized by the inability to speak in certain situations. (rug.nl)
  • Akinetic mutism can also occur as a result of damage to the mesencephalic region of the brain. (wikipedia.org)
  • Somnolent akinetic mutism: When the mesencephalic region is damaged, the condition is called somnolent akinetic mutism. (medigoo.com)
  • Akinetic mutism as a result of frontal lobe damage is clinically characterized as hyperpathic. (wikipedia.org)
  • Mesencephalic akinetic mutism is clinically categorized as somnolent or apathetic akinetic mutism. (wikipedia.org)
  • akinetic mutism - Also known as a persistent vegetative state. (neurolaw.com)
  • The authors report a case of episodicallly remitting akinetic mutism following subarachnoid hemorrhage. (elsevier.com)
  • Burruss, JW & Chacko, RC 1999, ' Episodically remitting akinetic mutism following subarachnoid hemorrhage ', Journal of Neuropsychiatry and Clinical Neurosciences , vol. 11, no. 1, pp. 100-102. (elsevier.com)
  • 4 One-quarter of patients enter the third stage of illness marked by akinetic mutism, hypotonic areflexic paresis, central pyrexia, and eventual death. (appliedradiology.com)
  • Akinetic mutism: disconnection of frontal-subcortical circuits. (semanticscholar.org)
  • Akinetic mutism could be explained by damage to the frontal lobe and or interruption of the complex frontal subcortical circuits. (medigoo.com)
  • The classical variety manifests as quadriplegia, lower cranial nerve paralysis, and mutism with preservation of vertical gaze and, most notably, intact consciousness indicated by abilities to communicate via eye movements. (hindawi.com)
  • Disabilities arising from TBI that have a direct impact on functioning and rehabilitative potential can be broadly classified into four main categories: decreased level of consciousness (LOC), and neuropsychiatric, neurocognitive, and neurobehavioral sequelae.5-8 Decreased level of consciousness refers to a diverse range of clinical states including coma, vegetative states, akinetic mutism, and locked-in states. (bcmj.org)
  • Akinetic mutism was first described in 1941 as a mental state where patients lack the ability to move or speak. (wikipedia.org)
  • Patients with akinetic mutism are not paralyzed, but lack the will to move. (wikipedia.org)
  • Akinetic mutism varies across all patients. (wikipedia.org)
  • Akinetic mutism is a symptom during the final stages of Creutzfeldt-Jakob disease (a rare degenerative brain disease) and can help diagnose patients with this disease. (wikipedia.org)
  • A variety of treatments for akinetic mutism have been documented, but treatments vary between patients and cases. (wikipedia.org)
  • Some patients with akinetic mutism have shown to improve with levodopa or dopamine agonist therapy, or by repleting dopamine in the motivational circuit with stimulants, antidepressants, or agonists such as bromocriptine or amantadine. (wikipedia.org)
  • Patients with CJD usually become akinetic mutism within approximately 6 months. (springer.com)
  • Fox and colleagues, including lead author, R. Ryan Darby, MD, PhD, formerly a fellow in Fox's lab at BIDMC and now of Vanderbilt University Medical Center, identified 28 cases in the medical literature in which brain injury disrupted volition, leaving patients with akinetic mutism - a lack of motivation to move or speak. (bidmc.org)
  • This is an appraisal of the varied clinical presentation and the neural substrate for akinetic mutism following stroke. (semanticscholar.org)
  • Akinetic mutism revealing an ischemic stroke. (amedeo.com)
  • Muteness or mutism (from Latin mutus , meaning 'silent') is an inability to speak, often caused by a speech disorder or surgery. (rug.nl)
  • Neurologic examination revealed decreased right upper extremity motor strength, hyperreflexia, and akinetic mutism. (jaoa.org)
  • Cyclosporin-associated akinetic mutism and extrapyramidal syndrome after liver transplantation. (semanticscholar.org)
  • This condition is a symptom of a problem and not a disease in itself.Types:Hyperpathic akinetic mutism: When the frontal lobe is involved, the akinetic mutism is known as hyperpathic akinetic mutism. (medigoo.com)
  • It leads to a state of akinetic mutism and death after a median disease duration of 6 months. (ajnr.org)
  • This state of akinetic mutism varies in intensity, but it is distinguished by drowsiness, lack of motivation, hyper-somnolence, and reduction in spontaneous verbal and motor actions. (wikipedia.org)
  • Within days, clinical condition declined, progressing to mutism, lack of interaction, anorexia, immobility and was treated with different combinations of antidepressants and antipsychotics, with the hypothesis of major depression. (scielo.br)
  • It can be caused by illness of the child, illness in utero, mutism of the parents or guardians, the general disorders of the muscles, the shyness of the child, and certain genetic disorders, among other causes. (rug.nl)
  • Akinetic mutism is a state in which the individual is unable to speak or move. (rug.nl)
  • Tumors or as far as the rv to as akinetic mutism, apallic state, or dissection. (goodbelly.com)
  • Visit our research pages for current research about Akinetic mutism treatments . (rightdiagnosis.com)
  • Akinetic mutism and bilateral anterior cerebral artery occlusion. (semanticscholar.org)
  • Three cases of bilateral anterior cerebral artery occlusion are presented with akinetic mutism. (semanticscholar.org)
  • This patient followed an atypical clinical course: 16 months had passed before she developed akinetic mutism, and periodic sharp waves had not been detected on EEG after 2 years in spite of her akinetic mutism. (nih.gov)
  • Hearing mutism is an obsolete term used in the late nineteenth and early twentieth century for specific language impairment . (rug.nl)
  • A new study reported that zolpidem, a drug normally used to treat insomnia, temporarily improved brain function in a patient suffering from akinetic mutism, a condition in which the person is alert but cannot speak or move. (news-medical.net)
  • Levodopa may be helpful to the treatment of akinetic mutism. (koreamed.org)
  • She presented with quadriplegia and mutism but was awake and aroused based on eye gaze communication. (hindawi.com)
  • Akinetic mutism is often the result of severe frontal lobe injury in which the pattern of inhibitory control is one of increasing passivity and gradually decreasing speech and motion. (wikipedia.org)
  • When the anterior cingulate cortex is damaged, it can result in akinetic mutism. (wikipedia.org)
  • Lesion locations causing akinetic mutism all fell within one network, defined by connectivity to the anterior cingulate cortex. (pnas.org)
  • In one case, a 59-year-old woman was administered intravenous magnesium sulfate in an attempt to resolve her akinetic mutism. (wikipedia.org)