Physics
Diagnostic Techniques, Neurological
Climate Change
Any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.
Gravity Sensing
United States National Aeronautics and Space Administration
Specific Gravity
Esophageal Sphincter, Lower
The physiologic or functional barrier to GASTROESOPHAGEAL REFLUX at the esophagogastric junction. Sphincteric muscles remain tonically contracted during the resting state and form the high-pressure zone separating the lumen of the ESOPHAGUS from that of the STOMACH. (Haubrich et al, Bockus Gastroenterology, 5th ed., pp399, 415)
Esophageal Sphincter, Upper
Esophagogastric Junction
Esophagus
Esophageal Motility Disorders
Disorders affecting the motor function of the UPPER ESOPHAGEAL SPHINCTER; LOWER ESOPHAGEAL SPHINCTER; the ESOPHAGUS body, or a combination of these parts. The failure of the sphincters to maintain a tonic pressure may result in gastric reflux of food and acid into the esophagus (GASTROESOPHAGEAL REFLUX). Other disorders include hypermotility (spastic disorders) and markedly increased amplitude in contraction (nutcracker esophagus).
Peristalsis
Intrinsic Factor
Cell Aging
Aging
Peptide Nucleic Acids
DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.
Cobalt Isotopes
Anemia, Pernicious
A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)
MedlinePlus
National Library of Medicine (U.S.)
An agency of the NATIONAL INSTITUTES OF HEALTH concerned with overall planning, promoting, and administering programs pertaining to advancement of medical and related sciences. Major activities of this institute include the collection, dissemination, and exchange of information important to the progress of medicine and health, research in medical informatics and support for medical library development.
HIV Infections
Life Expectancy
PubMed
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Genetic Fitness
Evolution, Molecular
Epistasis, Genetic
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
Selection, Genetic
Models, Genetic
Fukushima Nuclear Accident
Corrosion
Cesium Radioisotopes
Radioactive Pollutants
The expiry date of man: a synthesis of evolutionary biology and public health. (1/31363)
In industrialised countries, mortality and morbidity are dominated by age related chronic degenerative diseases. The health and health care needs of future populations will be heavily determined by these conditions of old age. Two opposite scenarios of future morbidity exist: morbidity might decrease ("compress"), because life span is limited, and the incidence of disease is postponed. Or morbidity might increase ("expand"), because death is delayed more than disease incidence. Optimality theory in evolutionary biology explains senescence as a by product of an optimised life history. The theory clarifies how senescence is timed by the competing needs for reproduction and survival, and why this leads to a generalised deterioration of many functions at many levels. As death and disease are not independent, future morbidity will depend on duration and severity of the process of senescence, partly determined by health care, palliating the disease severity but increasing the disease duration by postponing death. Even if morbidity might be compressed, health care needs will surely expand. (+info)Developmental synaptic changes increase the range of integrative capabilities of an identified excitatory neocortical connection. (2/31363)
Excitatory synaptic transmission between pyramidal cells and fast-spiking (FS) interneurons of layer V of the motor cortex was investigated in acute slices by using paired recordings at 30 degrees C combined with morphological analysis. The presynaptic and postsynaptic properties at these identified central synapses were compared between 3- and 5-week-old rats. At these two postnatal developmental stages, unitary EPSCs were mediated by the activation of AMPA receptors with fast kinetics at a holding potential of -72 mV. The amplitude distribution analysis of the EPSCs indicates that, at both stages, pyramidal-FS connections consisted of multiple functional release sites. The apparent quantal size obtained by decreasing the external calcium ([Ca2+]e) varied from 11 to 29 pA near resting membrane potential. In young rats, pairs of presynaptic action potentials elicited unitary synaptic responses that displayed paired-pulse depression at all tested frequencies. In older animals, inputs from different pyramidal cells onto the same FS interneuron had different paired-pulse response characteristics and, at most of these connections, a switch from depression to facilitation occurred when decreasing the rate of presynaptic stimulation. The balance between facilitation and depression endows pyramidal-FS connections from 5-week-old animals with wide integrative capabilities and confers unique functional properties to each synapse. (+info)Low resting potential and postnatal upregulation of NMDA receptors may cause Cajal-Retzius cell death. (3/31363)
Using in situ patch-clamp techniques in rat telencephalic slices, we have followed resting potential (RP) properties and the functional expression of NMDA receptors in neocortical Cajal-Retzius (CR) cells from embryonic day 18 to postnatal day 13, the time around which these cells normally disappear. We find that throughout their lives CR cells have a relatively depolarized RP (approximately -50 mV), which can be made more hyperpolarized (approximately -70 mV) by stimulation of the Na/K pump with intracellular ATP. The NMDA receptors of CR cells are subjected to intense postnatal upregulation, but their similar properties (EC50, Hill number, sensitivity to antagonists, conductance, and kinetics) throughout development suggest that their subunit composition remains relatively homogeneous. The low RP of CR cells is within a range that allows for the relief of NMDA channels from Mg2+ blockade. Our findings are consistent with the hypothesis that CR cells may degenerate and die subsequent to uncontrolled overload of intracellular Ca2+ via NMDA receptor activation by ambient glutamate. In support of this hypothesis we have obtained evidence showing the protection of CR cells via in vivo blockade of NMDA receptors with dizocilpine. (+info)Somatic recording of GABAergic autoreceptor current in cerebellar stellate and basket cells. (4/31363)
Patch-clamp recordings were performed from stellate and basket cells in rat cerebellar slices. Under somatic voltage clamp, short depolarizing pulses were applied to elicit action potentials in the axon. After the action potential, a bicuculline- and Cd2+-sensitive current transient was observed. A similar response was obtained when eliciting axonal firing by extracellular stimulation. With an isotonic internal Cl- solution, the peak amplitude of this current varied linearly with the holding potential, yielding an extrapolated reversal potential of -20 to 0 mV. Unlike synaptic or autaptic GABAergic currents obtained in the same preparation, the current transient had a slow rise-time and a low variability between trials. This current was blocked when 10 mM BAPTA was included in the recording solution. In some experiments, the current transient elicited axonal action potentials. The current transient was reliably observed in animals aged 12-15 d, with a mean amplitude of 82 pA at -70 mV, but was small and rare in the age group 29-49 d. Numerical simulations could account for all properties of the current transient by assuming that an action potential activates a distributed GABAergic conductance in the axon. The actual conductance is probably restricted to release sites, with an estimated mean presynaptic current response of 10 pA per site (-70 mV, age 12-15 d). We conclude that in developing rats, stellate and basket cell axons have a high density of GABAergic autoreceptors and that a sizable fraction of the corresponding current can be measured from the soma. (+info)Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB. (5/31363)
The developing cerebral cortex undergoes a period of substantial cell death. The present studies examine the role of the suicide receptor Fas/Apo[apoptosis]-1 in cerebral cortical development. Fas mRNA and protein are transiently expressed in subsets of cells within the developing rat cerebral cortex during the peak period of apoptosis. Fas-immunoreactive cells were localized in close proximity to Fas ligand (FasL)-expressing cells. The Fas-associated signaling protein receptor interacting protein (RIP) was expressed by some Fas-expressing cells, whereas Fas-associated death domain (FADD) was undetectable in the early postnatal cerebral cortex. FLICE-inhibitory protein (FLIP), an inhibitor of Fas activation, was also expressed in the postnatal cerebral cortex. Fas expression was more ubiquitous in embryonic cortical neuroblasts in dissociated culture compared to in situ within the developing brain, suggesting that the environmental milieu partly suppresses Fas expression at this developmental stage. Furthermore, FADD, RIP, and FLIP were also expressed by subsets of dissociated cortical neuroblasts in culture. Fas activation by ligand (FasL) or anti-Fas antibody induced caspase-dependent cell death in primary embryonic cortical neuroblast cultures. The activation of Fas was also accompanied by a rapid downregulation of Fas receptor expression, non-cell cycle-related incorporation of nucleic acids and nuclear translocation of the RelA/p65 subunit of the transcription factor NF-kappaB. Together, these data suggest that adult cortical cell number may be established, in part, by an active process of receptor-mediated cell suicide, initiated in situ by killer (FasL-expressing) cells and that Fas may have functions in addition to suicide in the developing brain. (+info)Metrifonate increases neuronal excitability in CA1 pyramidal neurons from both young and aging rabbit hippocampus. (6/31363)
The effects of metrifonate, a second generation cholinesterase inhibitor, were examined on CA1 pyramidal neurons from hippocampal slices of young and aging rabbits using current-clamp, intracellular recording techniques. Bath perfusion of metrifonate (10-200 microM) dose-dependently decreased both postburst afterhyperpolarization (AHP) and spike frequency adaptation (accommodation) in neurons from young and aging rabbits (AHP: p < 0.002, young; p < 0.050, aging; accommodation: p < 0.024, young; p < 0.001, aging). These reductions were mediated by muscarinic cholinergic transmission, because they were blocked by addition of atropine (1 microM) to the perfusate. The effects of chronic metrifonate treatment (12 mg/kg for 3 weeks) on CA1 neurons of aging rabbits were also examined ex vivo. Neurons from aging rabbits chronically treated with metrifonate had significantly reduced spike frequency accommodation, compared with vehicle-treated rabbits. Chronic metrifonate treatment did not result in a desensitization to metrifonate ex vivo, because bath perfusion of metrifonate (50 microM) significantly decreased the AHP and accommodation in neurons from both chronically metrifonate- and vehicle-treated aging rabbits. We propose that the facilitating effect of chronic metrifonate treatment on acquisition of hippocampus-dependent tasks such as trace eyeblink conditioning by aging subjects may be caused by this increased excitability of CA1 pyramidal neurons. (+info)Thiamine deficiency is prevalent in a selected group of urban Indonesian elderly people. (7/31363)
This cross-sectional study involved 204 elderly individuals (93 males and 111 females). Subjects were randomly recruited using a list on which all 60-75 y-old-people living in seven sub-villages in Jakarta were included. The usual food intake was estimated using semiquantitative food frequency questionnaires. Hemoglobin, plasma retinol, vitamin B-12, red blood cell folate and the percentage stimulation of erythrocyte transketolase (ETK), as an indicator of thiamine status, were analyzed. Median energy intake was below the assessed requirement. More than 75% of the subjects had iron and thiamine intakes of approximately 2/3 of the recommended daily intake, and 20.2% of the study population had folate intake of approximately 2/3 of the recommended daily intake. Intakes of vitamins A and B-12 were adequate. Biochemical assessments demonstrated that 36.6% of the subjects had low thiamine levels (ETK stimulation > 25%). The elderly men tended to have lower thiamine levels than the elderly women. The overall prevalence of anemia was 28.9%, and the elderly women were affected more than the elderly men. Low biochemical status of vitamins A, B-12 and RBC folate was found in 5.4%, 8.8 % and 2.9% of the subjects, respectively. Dietary intakes of thiamine and folate were associated with ETK stimulation and plasma vitamin B-12 concentration (r = 0.176, P = 0.012 and r = 0.77, P = 0.001), respectively. Results of this study suggest that anemia, thiamine and possibly vitamin B-12 deficiency are prevalent in the elderly living in Indonesia. Clearly, micronutrient supplementation may be beneficial for the Indonesian elderly population living in underprivileged areas. (+info)High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice. (8/31363)
Semipurified diets incorporating either perilla oil [high in alpha-linolenate, 18:3(n-3)] or safflower oil [high in linoleate, 18:2(n-6)] were fed to senescence-resistant SAMR1 mouse dams and their pups. Male offspring at 15 mo were examined using behavioral tests. In the open field test, locomotor activity during a 5-min period was significantly higher in the safflower oil group than in the perilla oil group. Observations of the circadian rhythm (48 h) of spontaneous motor activity indicated that the safflower oil group was more active than the perilla oil group during the first and second dark periods. The total number of responses to positive and negative stimuli was higher in the safflower oil group than in the perilla oil group in the light and dark discrimination learning test, but the correct response ratio was lower in the safflower oil group. The difference in the (n-6)/(n-3) ratios of the diets reflected the proportions of (n-6) polyunsaturated fatty acids, rather than those of (n-3) polyunsaturated fatty acids in the brain total fatty acids, and in the proportions of (n-6) and (n-3) polyunsaturated fatty acids in the total polyunsaturated fatty acids of the brain phospholipids. These results suggest that in SAMR1 mice, the dietary alpha-linolenate/linoleate balance affects the (n-6)/(n-3) ratio of brain phospholipids, and this may modify emotional reactivity and learning ability. (+info)
Age-associated Differences in Cardiovascular Inflammatory Gene Induction during Endotoxic Stress<...
Age-related alterations in signaling pathways in articular chondrocytes: implications for the pathogenesis and progression of...
Aberrant Innate Immune Functions of Dendritic Cells in Aged Humans (85.12) | The Journal of Immunology
201 Age-Associated Decline in Nav1.4 and Nav1.5 Isoforms of the Sodium Channel in Rat Heart | Heart
Researchers discover tactic to delay age-related disorders
Researchers Share Discoveries About Aging-Related Changes in Health and Cognition
The influence of HIV infection on the age dependence of squamous cell carcinoma of the skin in South Africa
Age effect on the default mode network, inner thoughts, and cognitive abilities. - Inserm
Age-Related Alterations in Retinal Tissue Perfusion and Volumetric Vessel Density | IOVS | ARVO Journals
Age-related decrease in proteasome expression contributes to defective nuclear factor-κB activation during hepatic ischemia...
Multiple Brain Markers are Linked to Age-Related Variation in Cognition
A review of longitudinal fMRI studies on age-related changes in functional brain activity
Age-Related Decline of Thyroid Function - David M. Odom, M.D.
Age-Dependent Changes in FasL (CD95L) Modulate Macrophage Function in a Model of Age-Related Macular Degeneration | IOVS | ARVO...
JCI -
Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice
Expanded CD4+ and CD8+ T cell clones in elderly humans. | The Journal of Immunology
Physiologic Thymic Involution Underlies Age-Dependent Accumulation of Senescence-Associated CD4+ T Cells. - Semantic Scholar
Evidence for an Age-Dependent Decline in Axon Regeneration in the Adult Mammalian Central Nervous System
Analysis of the age-related refractoriness of T-lymphocyte reactivity in humans<...
AGE RELATED CHANGES | MindMeister Mind Map
Findings that something in your blood can influence the way you think could lead to new treatments for age-associated declines...
Endotoxin-induced myocardial dysfunction in senescent rats | Critical Care | Full Text
Age related change in the supraspinatus tendon - Oxford Clinical Trials Research Unit
Molecular Vision: Age-dependent alteration of intraocular soluble heparan sulfate levels and its implications for proliferative...
Characterization of age-related variation in corneal biomechanical properties | Journal of The Royal Society Interface
Evidence for age-dependent impairment of ovalbumin heterogeneo...
Coenzyme Q10 (ubiquinone)
Human Aging: A Biological and Behavioral Longitudinal Study of Healthy Aged Males, 1957-1968
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. - PubMed - NCBI
Age-related effects of the neuromodulator d-serine on neurotransmission and synaptic potentiation in the CA1 hippocampal area...
Age influences inflammatory responses, hemodynamics, and cardiac prote by H. M. Linge, J. Y. Lee et al.
Obesity- and age-related alterations in FAT/CD36 translocation and lipin-1 subcellular localization in skeletal muscle of the...
2 Research Group Leaders in Ageing-related Diseases & Molecular
Age-related alterations of proteasome structure and function in aging epidermis. - PubMed - NCBI
S3.4 Genetic and environmental influences on the markers of biological age - Aldring og helse
IJMS | Free Full-Text | Oxidative Stress and Epigenetic Regulation in Ageing and Age-Related Diseases | HTML
IJMS | Free Full-Text | Oxidative Stress and Epigenetic Regulation in Ageing and Age-Related Diseases
Immune Mechanisms Underlying Age-Related Neurodegeneration in HIV Infection
- UC Davis
Plus it
Polymorphism of age-dependent changes in the production of a thf helpe by T Matsuzawa and B Cinader
Age-dependent changes in the exocytotic efficacy in Kir6.2 ablated mouse pancreatic β-cells - pdf descargar
Reduced Brain Volume May Predict Dementia in Healthy Elderly People
Why Is The Human Brain So Prone to Age-Related Diseases? - KINK AWARE THERAPISTS
Cortisol levels during human aging predict hippocampal atrophy and memory deficits
Immunosenescence and Cytomegalovirus: where do we stand after a decade? | Immunity & Ageing | Full Text
Age-related impairments reversed in animal model | SciSeek
Age-Dependent Impairment of Angiogenesis | Circulation
Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging | Circulation
Effects of aerobic fitness on aging-related changes of interhemispheric inhibition and motor performance - Fingerprint
-...
Calorie restriction initiated at middle age improved glucose tolerance without affecting age-related impairments of insulin...
Age related changes in speed and mechanism of adult skeletal
muscle stem cell migration - The Mathematical Institute,...
Effect of whole-body vibration training on body composition, exercise performance and biochemical responses in middle-aged mice...
Age-dependent Changes in Nervonic Acid-Containing Sphingolipids in Mouse Hippocampus - Analytical Products / Alfa Chemistry
産業医科大学|第1解剖学 研究業績
Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression
Hemp BC - British Columbia hemp and marijuana news and research
Loughborough University Institutional Repository: Bistable epigenetic states explain age-dependent decline in mesenchymal stem...
The role of estrogen in the development of age-related cognitive impairment and dementia<...
Localized functional age-related changes in the central retina assessed by multifocal ERG | JOV | ARVO Journals
Age-related effect of cells-donors of nuclei on efficiency of development of cloned rabbit embryos<...
Age related changes of the GABA-B receptor in the lumbar spinal cord of male rats and penile erection
Aging | Origin and pathophysiology of protein carbonylation, nitration and chlorination in age-related brain diseases and aging...
Age-related alterations in simple declarative memory and the effect of negative stimulus valence.
Medical Mistrust, Perceived Discrimination, and Satisfaction With Health Care Among Young-Adult Rural Latinos
Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction | RTI
Life Extension Immune Senescence Protection aging formula
Dr Kim Drake
Comparative pharmacokinetics of three doses of percutaneous dihydrotestosterone gel in healthy elderly men - A clinical...
Bone-derived hormone reverses age-related memory loss in mice | EurekAlert! Science News
Low Testosterone Raises Risk of Age-Related Functional Disability
Plus it
Immune Senescence & Inflammaging | Bio-Rad
Impaired Progenitor Cell Activity in Age-Related Endothelial Dysfunction | JACC: Journal of the American College of Cardiology
The effect of alpha-actinin-3 deficiency on muscle aging | Garvan Institute of Medical Research
Age-related gene response of human corneal endothelium to oxidative stress and DNA damage. | Harvard Catalyst Profiles |...
Gender Differences in Insulin-like Growth Factor and Bone Mineral Density Association in Old Age: The Rancho Bernardo Study
Age-related increase of airway neutrophils in older healthy nonsmoking subjects<...
Immunosenescence - Wikipedia
Venous thromboembolism in pediatric patients: a single institution experience in Korea
Alzheimers disease (Advertisement) can be an age-associated disease seen as a - Novel targets for Alzheimers disease treatment
Increase in Presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid...
Effects of dietary lipids on renal function of aged rats
US7273453B2 - Method for analyzing the biological age of a subject
- Google Patents
Translating autophagy proteins: a novel aging pathway - The Kennedy Institute of Rheumatology
Effects of Medium-Chain Triglycerides on Cognitive Function in Older Subjects With Age-Related Cognitive Decline - AdisInsight
Moderate exercise training attenuates aging-induced cardiac inflammation, hypertrophy and fibrosis injuries of rat hearts |...
lncRNA Chronos is an aging-induced inhibitor of muscle hypertrophy | JCB
Effects of a Fall Preventive Exercise Program on Intrinsic Fall Risk Factors in Healthy Older Adults. - Full Text View -...
Welcome to Dr Niemandt
Interplay of ionizing radiation, oxygen, ROS and age-associated diseases
Aging-induced Cognitive Vulnerability to Infection and Injury: Role of Microglia - UCTV - University of California Television
Restorative Neurology and Neuroscience - Volume 35, issue 6 - Journals - IOS Press
Aging-associated alterations in myocardial inflammation and fibrosis: Pathophysiological perspectives and clinical implications...
Effect of aging on changes of nociception and Ca<sub>v</sub>2α1 expression patterns in seven inbred mouse...
JCI -
The role of mitochondria in aging
Medicine
Middle Ages[edit]. A manuscript of Al-Risalah al-Dhahabiah by Ali al-Ridha, the eighth Imam of Shia Muslims. The text says: " ... After the fall of the Western Roman Empire and the onset of the Early Middle Ages, the Greek tradition of medicine went into ... During the Middle Ages, the Catholic Church established universities which revived the study of sciences - drawing on the ... In China, archaeological evidence of medicine in Chinese dates back to the Bronze Age Shang Dynasty, based on seeds for ...
Fair Labor Standards Act of 1938
1967 Age Discrimination in Employment Act[edit]. The Age Discrimination in Employment Act (ADEA) of 1967 prohibited employment ... Some older workers were being denied health benefits based on their age and denied training opportunities prior to the passage ... Children under eighteen cannot do certain dangerous jobs, and children under the age of sixteen cannot work during school hours ... to allow an employer to pay less than the minimum wage to individuals whose earning or productive capacity is impaired by age, ...
Hour record
Current records by age-group[edit]. Age group. Male record. Distance (KM). Female record [86]. Distance (KM) ... Age 30-34 Date Rider Age Velodrome Distance (km) Supported by Equipment Notes ... Age 35-39 Date Rider Age Velodrome Distance (km) Supported by Equipment Notes ... Age 40-44 Date Rider Age Velodrome Distance (km) Supported by Equipment Notes ...
Soul
Spirituality, New Age, and new religions[edit]. Brahma Kumaris[edit]. In Brahma Kumaris, human souls are believed to be ... 2009). Superstition: Belief in the Age of Science. Princeton University Press. p. 90. ISBN 978-0-691-13355-3 ... 2009). Superstition: Belief in the Age of Science. Princeton University Press. ISBN 978-0-691-13355-3 ...
The Gutenberg Galaxy
Electronic age[edit]. The global village[edit]. In the early 1960s, McLuhan wrote that the visual, individualistic print ... Electronic age. For the break between the time periods in each case the occurrence of a new medium is responsible, the hand- ... So language was the last art to accept the visual logic of Gutenberg technology, and the first to rebound in the electric age.[ ... In this new age, humankind will move from individualism and fragmentation to a collective identity, with a "tribal base." ...
Observational learning
As age increases, age-related observational learning motor skills may decrease in athletes and golfers.[14] Younger and skilled ... Age difference[edit]. Albert Bandura stressed that developing children learn from different social models, meaning that no two ... For example, girls aged 11 to 14 performed better on a motor performance task when they thought it was demonstrated by a high- ... Children aged 6 to 8 in an indigenous heritage community in Guadalajara, Mexico participated in hard work, such as cooking or ...
RAD51
Chemotherapy and aging[edit]. In aged and chemotherapy treated females, oocytes and follicles are depleted by apoptosis ( ... DNA damage-induced oocyte apoptosis depends on the efficiency of the DNA repair machinery that in turn declines with age. ... Survival of oocytes following chemotherapy or aging can be enhanced by increased expression of Rad51.[35] The Rad51-induced ... "Enhancing survival of mouse oocytes following chemotherapy or aging by targeting Bax and Rad51". PLoS ONE. 5 (2): e9204. doi ...
Pu'er tea
The smell of aged pu'erh may vary, with an "aged" but not "stuffy" odor. The taste of aged raw pu'erh or ripe pu'erh should be ... Because of its ability to age without losing "quality", well aged good pu'er gains value over time in the same way that aged ... Bǐngchá and zhuancha thus age more quickly than golden melon, tuocha, or jincha. Larger bingcha age slower than smaller ' ... Aging and storage[edit]. Pu'er teas of all varieties, shapes, and cultivation can be aged to improve their flavor, but the ...
Brain-derived neurotrophic factor
Aging[edit]. BDNF levels appear to be highly regulated throughout the lifetime both in the early developmental stages and in ... Although BDNF is needed in the developmental stages, BDNF levels have been shown to decrease in tissues with aging.[90] Studies ... Tapia-Arancibia L, Aliaga E, Silhol M, Arancibia S (November 2008). "New insights into brain BDNF function in normal aging and ... it does suggest there is a relationship that might explain some of the cognitive decline that occurs during aging. ...
Olfactory system
Age[edit]. Age is the strongest reason for olfactory decline in healthy adults, having even greater impact than does cigarette ... 2% of people under 65 years of age have chronic smelling problems. This increases greatly between people of ages 65 and 80 with ... Prevalence rose from 4.2% at age 40-49 to 39.4% at 80 years and older and was higher in men than women, in blacks and Mexican ... Age-related changes in smell function often go unnoticed and smell ability is rarely tested clinically unlike hearing and ...
Amyotrophic lateral sclerosis
Age of onset[edit]. ALS can also be classified based on the age of onset. While the peak age of onset is 58 to 63 for sporadic ... The disease can affect people of any age, but usually starts around the age of 60 and in inherited cases around the age of 50.[ ... the lowest prevalence was in the 18-39 age group, while the highest prevalence was in the 70-79 age group.[18] Sporadic ALS ... "Aging and Disease. 4 (5): 295-310. doi:10.14336/AD.2013.0400295. PMC 3794725. PMID 24124634.. ...
In-group favoritism
Developmental age[edit]. Fehr, Bernhard, and Rockenbach (2008), in a study conducted on children, found that boys displayed in- ... Thus males tended to show in-group biases from a younger age than females, as was evident in the experiment.[29] ... group favouritism from ages 3-8, whereas girls did not display such tendencies.[29] The experiment involved usage of an "envy ...
R-value (insulation)
Insulation aging[edit]. R-values of products may deteriorate over time. For instance the compaction of loose fill cellulose ... However, the LTTR effectively provides only an eight-year aged R-value, short in the scale of a building that may have a ... There are other foams which do not change significantly with aging because they are blown with water or are open-cell and ... Foil-faced polyisocyanurate rigid panel (pentane expanded) aged 5-10 years 0.97. R-5.5. 38 ...
Jewish diaspora
a b Hegermann, Harald (2008) "The Diaspora in the Hellenistic Age." In: The Cambridge History of Judaism, Vol. 2. Eds.: Davies ... Kleiner, Fred (2010). Gardner's Art Through the Ages: A Global History, Enhanced, Volume I: 1. Wadsworth Publishing. p. 262. ... Middle Ages. Ashkenazi Jews. Ashkenazi Jews is a general category of Jewish populations who immigrated to what is now Germany ... Antonia Tripolitis (2002). Religions of the Hellenistic-Roman Age. Wm. B. Eerdmans Publishing. pp. 61-62. ISBN 9780802849137.. ...
University of Turin
A famous student of this age was Joseph-Louis Lagrange. Age of Victor Emmanuel I (1817-1832)[edit]. ...
Charlton, London
Middle Ages[edit]. Charlton is assessed in the Domesday Book of 1086 at one "sulung", which is commonly held to have been the ... 42.95 of people in the ward were aged 20-44.[27] ...
Biarritz
Middle Ages[edit]. The oldest mention of the city appears in a cartulary, Bayonne's Golden book, from 1186, where it is named ... From the Middle Ages and Early modern period a watchtower has looked down over the sea at Biarritz, from "La Humade", waiting ... Two population centers are attested in the Middle Ages. On the one hand, the église Saint-Martin was active in the ...
Vitamin D toxicity
Tuohimaa P (March 2009). "Vitamin D and aging". The Journal of Steroid Biochemistry and Molecular Biology. 114 (1-2): 78-84. ... Premature aging[edit]. Complex regulatory mechanisms control metabolism. Recent epidemiologic evidence suggests that there is a ... Keisala T, Minasyan A, Lou YR, Zou J, Kalueff AV, Pyykkö I, Tuohimaa P (July 2009). "Premature aging in vitamin D receptor ... Tuohimaa P, Keisala T, Minasyan A, Cachat J, Kalueff A (December 2009). "Vitamin D, nervous system and aging". ...
List of oldest trees
Old trees with estimated ages[edit]. Note: The ages of the trees in this list are speculative and probably unreliable. ... Individual trees with verified ages[edit]. Name. Age. (years). Species. Location. Country. Notes ... There are three tables of trees, which are listed by age and species. The first table includes trees for which a minimum age ... Age. (years). Species. Location. Country. Notes ?[nb 2]. 5,069. Great Basin bristlecone pine. Pinus longaeva. White Mountains ( ...
Paleoclimatology
Imbrie, John (1979). Ice ages: solving the mystery. Cambridge MA: Harvard University Press. ISBN 978-0-674-44075-3. .. ... There has been a cycle of ice ages for the past 2.2-2.1 million years (starting before the Quaternary in the late Neogene ... Ice core data for the past 800,000 years (x-axis values represent "age before 1950", so today's date is on the left side of the ... It has been observed that ice ages deepen by progressive steps, but the recovery to interglacial conditions occurs in one big ...
Black hole
Golden age. See also: History of general relativity. In 1958, David Finkelstein identified the Schwarzschild surface as an ... These results came at the beginning of the golden age of general relativity, which was marked by general relativity and black ...
Keswick, Cumbria
Between ages 10 and 20 the comparable figures are 10.2 and 12.1; and from ages 20 to 44, 25.9 as against 34.3. The percentage ... Clarkson, Tim (2014). Strathclyde and the Anglo-Saxons in the Viking Age. Edinburgh: John Donald. ISBN 978 1 906566 78 4. .. ... The antiquary W G Collingwood, commenting in 1925 about finds in the area, wrote that they showed "Stone Age man was fairly at ... Keswick's recorded history starts in the Middle Ages. The area was conquered by the Anglo-Saxon Kingdom of Northumbria in the ...
Cerebral palsy
The age when CP is diagnosed is important, but medical professionals disagree over the best age to make the diagnosis.[66] The ... Aging[edit]. Children with CP may not successfully transition into using adult services because they are not referred to one ... Zaffuto-Sforza, Celeste D. (February 2005). "Aging with cerebral palsy". Physical Medicine and Rehabilitation Clinics of North ... Prevalence of cerebral palsy is best calculated around the school entry age of about 6 years, the prevalence in the U.S. is ...
Portugal in the Middle Ages
Flags of Portugal during the Middle Ages[edit]. Five different flags were used during the period from 1139 until 1415. As seen ... In 1171 Afonso concluded a seven years truce with the Moors; weakened by his wound and by old age, he could no longer take the ... In 1122 Afonso became fourteen, the adult age in the 12th century. He made himself a knight on his own account in Zamora ... In 1184, in spite of his great age, King Afonso of Portugal still had sufficient energy to relieve his son Sancho, who was ...
Gaeta
In the classical age Caieta, famous for its lovely and temperate climate, like the neighbouring Formia and Sperlonga, was a ... Middle Ages[edit]. Further information: Duchy of Gaeta and List of Hypati and Dukes of Gaeta ... On the death of Docibilis II (954), who first took the title dux, the duchy passed from its golden age and entered a decline ... At the beginning of the Middle Ages, after the Lombard invasion, Gaeta remained under suzerainty of the Byzantine Empire. In ...
Arabian Peninsula
In the Middle Ages, these included the Abbasids of Baghdad, and the Fatimids, Ayyubids and Mamluks of Egypt.[63] ... Middle Ages[edit]. Despite its spiritual importance, in political terms Arabia soon became a peripheral region of the Islamic ... Age of the Caliphs Expansion under Muhammad, 622-632/A.H. 1-11 ... 3.3 Middle Ages. *3.4 Modern history *3.4.1 Late Ottoman rule ... the stone tools from the Middle Paleolithic age along with fossils of other animals discovered at Ti's al Ghadah, in ...
History of Nova Scotia
Golden Age of Sail[edit]. Photo of William D. Lawrence being built at Maitland in 1873. The ship was the longest wooden ship ... Julian Gwyn, "Golden Age or Bronze Moment? Wealth and Poverty in Nova Scotia: The 1850s and 1860s," Canadian Papers in Rural ... Outmigration increased as the 19th century wore on.[80][81] Thus the era was indeed a golden age but mainly for a small and ... The idea of a past golden age came to prominence in the early 20th century by economic reformers in the Maritime Rights ...
Folate
For children ages 1-17 years the PRIs increase with age from 120 to 270 μg/day. These values differ somewhat from the U.S. RDAs ... Age Infants (AI) Infants (UL) Children and adults (RDA) Children and adults (UL) Pregnant women (RDA) Pregnant women (UL) ... Age-related macular degeneration[edit]. A sub study of the Women's Antioxidant and Folic Acid Cardiovascular Study published in ... For women and men over age 18 the PRI is set at 330 μg/day. PRI for pregnancy is 600 μg/day, for lactation 500 μg/day. ...
Marcellus Formation
Swank, J.H. (1892). History of the Manufacture of Iron in All Ages, and Particularly in the United States From Colonial Times ... Age[edit]. On the geological timescale, the Marcellus occurs in the Middle Devonian epoch, of the Devonian period, in the ... Relative age dating of the Marcellus places its formation in the Cazenovia subdivision of the Givetian faunal stage, or 391.9 ... Stratigraphically, the Marcellus is the lowest unit of the Devonian age Hamilton Group, and is divided into several sub-units. ...
Body armor
Williams, Alan (2003). The Knight and the Blast Furnace: A History of the Metallurgy of Armour in the Middle Ages & the Early ... Initially constructed from leather and brass, and then bronze and iron during the Bronze and Iron Ages, they soon came to be ... In European history, well-known armor types include the mail hauberk of the early medieval age, and the full steel plate ... In antiquity and in the Middle Ages, shields were used by foot soldiers and mounted soldiers. Even after the invention of ...
Adolescence (15-17 years old) | CDC
CDCs BAM! Body and Mind is a website designed for kids 9 through 13 years of age to give them the information they need to ... CDCs BAM! Body and Mind is a website designed for kids 9 through 13 years of age, to give them the information they need to ... The U.S. Department of Agriculture provides information on health and nutrition for children over 5 years of age. ... The U.S. Department of Agriculture provides information on health and nutrition for 2 through 5 years of age. ...
Sleep Deprivation Linked To Aging Skin, Study Suggests | HuffPost
Now heres another good reason to get enough sleep: sleep deprivation also could cause your skin to age faster, according to a ... The amount of sleep one needs depends on a persons age. Most experts recommend that adults get between seven and eight hours ... The study involved 60 pre-menopausal women between the ages of 30 and 49, with half of them falling into the poor quality sleep ... Sleep deprived women show signs of premature skin aging and a decrease in their skins ability to recover after sun exposure," ...
X-Ray Exam: Bone Age Study (for Parents) - Nemours Kidshealth
A bone age study can help evaluate how a childs skeleton is maturing, which can help doctors diagnose conditions that delay or ... A childs bone age (also called the skeletal age) is assigned by determining which of the standard X-ray images in the atlas ... A difference between a childs bone age and his or her chronological age might indicate a growth problem. But such differences ... which is based on data from large numbers of other kids of the same gender and age. The bone age is measured in years. ...
Adult Immunization Schedule by Vaccine and Age Group | CDC
Persons age 6 months or older: 1 dose any influenza vaccine appropriate for age and health status annually ... HPV vaccination recommended for all persons through age 26 years: 2- or 3-dose series depending on age at initial vaccination ... Adolescents and young adults age 16-23 years (age 16-18 years preferred) not at increased risk for meningococcal disease: Based ... persons with diabetes mellitus age younger than 60 years, shared clinical decision-making for persons age 60 years or older) ...
Understanding of gravity in the Middle Ages | Physics Forums - The Fusion of Science and Community
I would say yes if you are talking about a temporal frame of reference, i.e. Middle Ages vs. Information Age. ... Similar Discussions: Understanding of gravity in the Middle Ages * Middle of gravity (Replies: 5) ... I have read that in the Middle Ages people believed that angels pushed the Moon in its orbit, the angelic push presumably being ... What else did people in the Middle Ages know about gravity? Did they, for example, know that the same force which was ...
Nathan Shock Centers of Excellence
... of the NIA funds Nathan Shock Centers of Excellence in the Basic Biology of Aging across the U.S. There are currently 5 funded ... The Division of Aging Biology (DAB) of the NIA funds Nathan Shock Centers of Excellence in the Basic Biology of Aging across ... Personalized Geroscience: Age x Genotype x Environment. June 1-2, Seattle Washington. In coordination with the 2016 AGE meeting ... Develop a Oklahoma Geroscience Consortium to bring together all faculty in Oklahoma who are interested in aging and age-related ...
Memory and aging - Wikipedia
"Psychology and Aging. American Psychological Association. Retrieved 9 May 2011.. *^ Kahana, Michael. "Age Dissociates Recency ... Normal aging[edit]. Normal aging is associated with a decline in various memory abilities in many cognitive tasks; the ... Age-related memory loss, sometimes described as "normal aging", is qualitatively different from memory loss associated with ... As they age, their ability to multi-task seems to decline; thus after an interruption it is often more difficult for an aging ...
Sponsored Collection | A new age in scanning electron microscopy: Applications in the life sciences | Science
A new age in scanning electron microscopy: Applications in the life sciences (PDF, 12 MB) ... Sponsored Collection , A new age in scanning electron microscopy: Applications in the life sciences ... Sponsored Collection , A new age in scanning electron microscopy: Applications in the life sciences ... Sponsored Collection , A new age in scanning electron microscopy: Applications in the life sciences ...
Age In Place | The National Aging In Place Council
S.C. Aging in Place Coalition Transitions to National Aging in Place Greater Charleston Chapter CHARLESTON, SC - To better ... the South Carolina Aging in Place Coalition has become a Chapter of the National Aging in ... Read More ... What to Expect in your 50s, 60s, and 70s As we age, our health needs are constantly changing. Knowing what to expect as you ... serve the community and help individuals find the resources to age in place, ...
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aging-gi
In a study conducted to understand the effect of aging on carbohydrates digestion and absorption, both older and younger age ... manometric studies of the colon in the elderly fail to identify any age-related decrease in the motility. In the aged colon, ... but not in the younger age groups (3) . Finally, the brush border peptidases seem also to remain intact with older age, and ... it is worth mentioning that serum insulin levels increase with age, but the sensitivity to insulin diminishes with age (1) . ...
Rejuvenation (aging) - Wikipedia
Ageless Aging brain American Academy of Anti-Aging Medicine Biogerontology Biological immortality DNA repair DNA damage theory ... Life extension strategies often study the causes of aging and try to oppose those causes in order to slow aging. Rejuvenation ... de Grey, Aubrey; Rae, Michael (September 2007). Ending Aging: The Rejuvenation Breakthroughs that Could Reverse Human Aging in ... was applied as a robust method of decelerating aging and the development of age-related diseases. The biomedical gerontologist ...
Active Aging Coalition
We are encouraged to broaden our perspectives of aging and deepen our value of elders in our community. ... service providers about local resources that support senior living and opportunities for community involvement across the ages ... Welcome to Active Aging Coalition Welcome!. This site provides information for seniors, their families, and other senior ... advocates about local resources that support senior living and opportunities for community involvement across the ages.. As of ...
Aging | SpringerLink
... from the mitotic age of cells to the organismal-wide aging of tissues and organs. The appearance of cancer is only one clinical ... Aging is defined at many levels, from the mitotic age of cells to the organismal-wide aging of tissues and organs. The ... Aging. During an organisms life span almost every aspect of its phenotype will undergo modification. The complexity of aging ... Age-associated epithelial cancers, such as breast cancer, colon cancer, and prostate cancer, however, contribute significantly ...
aging - Wiktionary
Aging Biotech Info Home
The Aging Population
As people age, normal changes occur in their speech, language, memory, and swallowing. In addition, their chances of having a ... The Aging Population. The population in the United States is aging. Between 2010 and 2030, the number of Americans over the age ... Partnership for Health in Aging. The Partnership for Health in Aging (PHA) was formed by the American Geriatrics Society to "to ... There are many organizations dedicated to research on aging, advocating for the elderly, and promoting healthy aging. SLPs ...
Cellular Aging | SpringerLink
The level of investigative activity into the mechanisms of aging at the cellular and molecular level has increased dramatically ... Effects of age on cell division capacity. In: Danon D, Shock NW, Marois M, eds. Aging: A Challenge to Science and Society. New ... Aging and the immune system. In: Warner HR, Butler RN, Sprott RL, et al, eds. Modern Biological Theories of Aging. New York, NY ... Theories of aging: a perspective. In: Warner HL, Butler RN, Sprott RL, et al, eds. Modern Biological Theories of Aging. New ...
Aging mechanisms | PNAS
... mechanisms of aging. In the session, Aging Mechanisms, two topics were discussed: first is aging at the organismal level, which ... A mutant model mouse is useful for studies of aging. The klotho phenotype (premature aging) is caused by a disruption of the ... Studies of the mutant mouse, klotho, showing premature aging, raise a possibility that mammals have an "anti-aging hormone." A ... Frontier experimental studies of aging at the molecular level are leading to fascinating hypotheses that aging is the price we ...
Healthy Aging: MedlinePlus
As we age, our bodies and minds change. Read more. ... National Institute on Aging) * Well-Aged Mind: Maintaining Your ... Participating in the Arts Creates Paths to Healthy Aging (National Institute on Aging) ... The primary NIH organization for research on Healthy Aging is the National Institute on Aging ... National Institute on Aging) * Memory Loss: 7 Tips to Improve Your Memory (Mayo Foundation for Medical Education and Research) ...
Aging - Business Insider
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Spirituality and Aging
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Center on Aging
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FSSA: About Aging
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Aging | Psychology Today
... the number of Americans age 65 and over is projected to reach some 71.5 million people, and nearly 10 million of them will be ... age 85 and older. Today, many seniors report better health, greater wealth, and higher levels of education than seniors in past ... The Fundamentals of Aging. By 2030, the number of Americans age 65 and over is projected to reach some 71.5 million people, and ... Middle-Age Erection Changes: What Couples Need to Know By Michael Castleman M.A. on January 15, 2019 in All About Sex ...
NBER Aging Program
... when the baby boom generation was between the ages of 22 and 40, and when life expectancy at age 62 (the age of eligibility for ... Bulletin on Aging and Health. Book series. The Economics of Aging. International Social Security Jon Skinner, Program Director ... NBER Aging Program. The Economics Of Aging Program involves research on the health and economic circumstances of individuals as ... Work and Retirement at Older Ages. While the determinants of work and retirement have been core components of the Aging Program ...
Mate-Selection Scale And Aging
... to see if flies preferentially select mates on the basis of rate of aging and not not absolute age of its potential mates age ... This is not the first theory of Aging to recognize that the cessation of growth was involved in senescence. G. P. Bidder (1932 ... Proposed experiment to test hypothesis that Mate-Selection drives the persistence of the aging phenotype in Drosophila ... one of the first to speak on the evolution of aging, proposed that aging and subsequent dying occurs to the benefit of the ...
Nuke Plants Aging Disgracefully | WIRED
... corrosion and other signs of age at U.S. nuclear power plants have been the root of a growing list of near-miss accidents that ... Nuke Plants Aging Disgracefully. Cracks, corrosion and other signs of age at U.S. nuclear power plants have been the root of a ... Once these things show this type of aging, its time for the utilities to retire them. If a reactor leaks, its time to shut it ... Davis-Besse is among a growing number of aging plants plagued by corrosion and other defects caused by decades of intense heat ...
Ages Questionnaire
Aging | metallurgy | Britannica.com
... precipitate throughout the sample by aging at an elevated temperature that is well below the temperature used for the initial ... Other articles where Aging is discussed: metallurgy: Increasing strength: … ... precipitate throughout the sample by aging at an elevated temperature that is well below the temperature used for the initial ...
Baby boomersNational Aging2019LongevityResearchersAdministration on AgAmericaTissues and organsWorkforceProcessAdultsDementiaPhenotypeDisability Resource CenterYoungerOlderINconnect AllianceProcessesCellularLifespanDiseasesHealth2016Alzheimer'sBiologicalPhysiologicalPeopleAmericansHumansCaregiversOrganismalElderlyBiomarkersDysfunctionSkin elasticityCreamsHealthyPopulationResearchIncreasesHoosiersConnectionsHealthierYearsCenterExaminesAwareness of the needsServicesPopulationsMechanismsSenescenceWiselyStudyMiceIssuesScientists
Baby boomers6
- It is expected that there will be 71 million people aged 65 years old and older when all baby boomers are at least 65 years old in 2030. (cdc.gov)
- Baby boomers are now between the ages of 50 and 68, and their initiation of retirement benefits is accelerating. (nber.org)
- The societal impact of aging baby boomers is compounded by increasing longevity. (nber.org)
- There are approximately 76 million baby boomers in the United States, and their ages range from the early fifties to the early seventies. (psychcentral.com)
- The practice of Aging Life Care™ and the role of care providers have captured a national spotlight, as generations of Baby Boomers age in the United States and abroad. (prweb.com)
- books.google.com - By 2030, when most American baby boomers will have retired, all the large industrial economies will see a massive increase in the old age population. (google.com)
National Aging1
- Aging Life Care Professionals throughout the country will celebrate National Aging Life Care Month this May by providing seminars, webinars, special events, open houses, and other educational activities for the public. (prweb.com)
20192
Longevity5
- Two decades have past since Caleb Finch in Longevity Senescence and the Genome exhaustively exposed the persistence of negligible senescence in nature and yet the dominant theories of aging continue to lack viable mechanisms or explanations for negligible senescence within their models. (google.com)
- Meet species that exemplify all the realms of aging: longevity, reproductive health, social status, wisdom, and finally, everything that surrounds the final chapter of life, death. (cbc.ca)
- One of the genetic factors that influences the rate of aging and longevity of an organism is the length of telomeres that. (buzzle.com)
- Optimal aging goes beyond good health and longevity. (bgsu.edu)
- Because the company aims to market drugs that slow or prevent the diseases of aging rather than extend longevity, sirtuin activators' effects on lifespan may not matter. (technologyreview.com)
Researchers18
- Researchers found that those who didn't sleep well exhibited more signs of skin aging including fine lines, uneven pigmentation and reduced skin elasticity. (huffingtonpost.com)
- Recent efforts made by researchers from diverse fields have merged into a line of frontier sciences to search for the "absolute" mechanisms of aging. (pnas.org)
- This has had a magnetic effect on the size, scope, and productivity of the program as new researchers have been drawn into the field by the prominent senior scholars already working on aging issues. (nber.org)
- The Sloan Center on Aging & Work at Boston College understands this need, and has invited international research fellows to connect with researchers in the United States to examine topics on aging in the workplace. (bc.edu)
- For example, the Sloan Center and other partners have started collaborating with researchers from the Behavioural Science Institute of Radboud University Nijmegen, who have organized a Dutch knowledge platform on sustainable systems of support for aging workers ( www.nkdi.nl ). (bc.edu)
- Aging in the Wild takes us from the African savannah to the French Alps - and beyond - guided by passionate researchers who reveal their latest discoveries. (cbc.ca)
- Researchers found that seniors who have positive outlooks on aging are 40% more likely to recover from a disability than those with negative attitudes. (psychcentral.com)
- Now, researchers at the Salk Institute for Biological Studies have replicated premature aging in the lab, allowing them to study aging-related disease in a dish. (newswise.com)
- Not so long ago, researchers thought we aged the same way our cars do-after years of wear and tear, the engine is bound to break down. (aarp.org)
- On Wednesday, some of the leading researchers in the field met at Harvard University to discuss the state of anti-aging science at the Aging & Healthy Lifespan conference. (aarp.org)
- Researchers have found that by changing just one of the genes that affects aging, they were able to double the worm's lifespan. (aarp.org)
- Researchers need to study the twin impacts of long-term HIV infection and aging to assess their impact on overall health and well-being. (thebody.com)
- By pooling several quantitative biomarkers of aging researchers were able to predict the physical and mental performance of test subjects on tasks designed to assess their actual biological age. (extremetech.com)
- In a landmark study sure to provoke interest, researchers from the University of Edinburgh have regenerated an aged organ - in vivo, inside a living animal - to its youthful state though noninvasive manipulation of genes. (extremetech.com)
- and her talk will highlight the primary challenges that researchers face in understanding the key issues facing adults aging with I/DD. (constantcontact.com)
- In the recent study, the researchers tested 10 flavonoids , which are naturally occurring compounds with antioxidant and anti-inflammatory properties, in aging mice. (medicalnewstoday.com)
- In the 1950s, researchers began to question the validity of accelerated aging tests which relied on dry heat and a single temperature, pointing out that relative humidity affects the chemical processes which produce paper degradation and that the reactions which cause degradation have different activation energies. (wikipedia.org)
- This led researchers like Baer and Lindström to advocate accelerated aging techniques using the Arrhenius equation and a realistic relative humidity. (wikipedia.org)
Administration on Ag6
- But in a few states, the senior citizen population grew significantly faster than the rest of the country, according to a recent Administration on Aging report. (huffingtonpost.com)
- The Administration on Aging (AoA) is the U.S. federal agency charged with administering the Older Americans Act (OAA), the principal federal legislation promoting client advocacy, system building, and the delivery of social services for America's elderly population. (encyclopedia.com)
- and insurance/benefits outreach and counseling program (Administration on Aging, http://www.aoa.gov ). (encyclopedia.com)
- To strengthen the involvement of the Administration on Aging in the development of policy alternatives in long-term care by participating in all departmental and interdepartmental activities concerning development of long-term-care health services, review all departmental regulations regarding community-based long-term care, and provide a leadership role for AoA, state, and area agencies in development and implementation of community-based long-term care. (encyclopedia.com)
- Eldercare Locator is a service by the U.S. Administration on Aging to help users find resources for older adults. (acog.org)
- Funded by the Administration on Aging, Dr. Eric Coleman's Care Transition Intervention (CTI) model was selected to be implemented in partnership with the Hospital of Central Connecticut (HCC). (ct.gov)
America2
- Forward 179 THE AGING OF AMERICA DAVID SATCHER, MD, PhD Centers for Disease Control and Prevention Dramatic shifts are occurring in the structure of the American population. (jhu.edu)
- During the 20th century we have Journal of Health Care for the Poor and Underserved · Vol. 7, No. 3 · 1996 180 The Aging of America witnessed a dramatic change in life expectancy. (jhu.edu)
Tissues and organs3
- Aging is an accumulation of damage to macromolecules, cells, tissues and organs. (wikipedia.org)
- Aging is defined at many levels, from the mitotic age of cells to the organismal-wide aging of tissues and organs. (springer.com)
- Wear and tear theory: According to the wear and tear theory of aging, tissues and organs eventually die after years of damage. (news24.com)
Workforce1
- The Partnership for Health in Aging (PHA) was formed by the American Geriatrics Society to "to prepare America's formal and informal caregiving workforce to provide quality care for America's aging population, and to ensure the financial feasibility of providing that care. (asha.org)
Process39
- I'm studying whether we can separate the process of functional reprogramming of cells from the process of aging reprogramming of cells. (nautil.us)
- Age, on the other hand, is just the degree of usefulness of that cell, and it's mostly an epigenetic process. (nautil.us)
- Rejuvenation is a medical discipline focused on the practical reversal of the aging process. (wikipedia.org)
- The appearance of cancer is only one clinical manifestation of the aging process. (springer.com)
- While these efforts certainly have yielded a wealth of descriptive information and some fundamental changes in our perception of the aging process, definitive knowledge of the cause or causes of aging remains elusive. (springer.com)
- For example, it is not known if all cell populations in the body are vulnerable to aging, or if the nature of the aging process is similar in all cell populations in the body. (springer.com)
- Werner's syndrome: a review of its symptomology, natural history, pathology features, genetics and relationship to the natural aging process. (springer.com)
- Thus, the aging process is stochastic, and it contrasts with the programmed processes undertaken during early development. (pnas.org)
- This is an encouraging result because those two constructs are among the first that start to go with the aging process. (aarp.org)
- The answer is as complex as the aging process itself. (news24.com)
- Aging is the process of growing old or maturing. (news24.com)
- Although many scientists agree that cross-linking plays a role in aging, there is not enough scientific evidence to confirm that this process is a primary cause of aging. (news24.com)
- Although free radicals are needed for the body to produce energy, maintain immunity, transmit nerve signals, produce hormones, and contract muscles, they may also contribute to the process of aging. (news24.com)
- The bottom line is we cannot change the fact that we are aging, but we can change how we view the process. (psychcentral.com)
- Newswise - LA JOLLA, CA-The current pace of population aging is without parallel in human history but surprisingly little is known about the human aging process, because lifespans of eight decades or more make it difficult to study. (newswise.com)
- The slow progression and complexity of the aging process makes it very hard to study the pathogenesis of cardiovascular and other aging-related disorders," says Izpisúa Belmonte. (newswise.com)
- Progeria's striking features resemble the aging process put on fast-forward and afflicted people rarely live beyond 13 years. (newswise.com)
- Scientists are particularly interested in Progeria in the hopes that it might reveal clues to the normal human aging process. (newswise.com)
- There is also evidence that defective lamin A accumulates during the normal aging process via the sporadic use of the alternative splice site, " explains Izpisua Belmonte. (newswise.com)
- Gruman predicts that we're on the cusp of a dramatic change in our expectations about the aging process. (medicinenet.com)
- Over the last 20 years, they have found a handful of genes that control the way we age-and they hope to manipulate them to slow the process down. (aarp.org)
- Why is it that we are told to reduce our wrinkles, and fight the inevitable aging process. (blogher.com)
- The aging process is inevitable, and every living organism has to go through it whether one likes it or not. (buzzle.com)
- Aging process is a biological phenomenon, which everyone has to undergo at a certain point of life. (buzzle.com)
- Aging process in humans is a complex and natural process that brings about many physical, as well as psychological changes. (buzzle.com)
- Aging is a natural process that takes place as a consequence of various biological events over the course of one's lifespan. (buzzle.com)
- Aging process in men and women works at different pace. (buzzle.com)
- A famous group of studies conducted in 2002 at the University of California at Berkeley suggested that the combination of supplements acetyl-L-carnitine and alpha-lipoic acid could slow the aging process. (buzzle.com)
- adverse reactions (and distinguishing whether adverse reactions are a side effect of medicines or related to the aging process, HIV or something else. (thebody.com)
- This website will equip you with practical information and effective strategies to help you slow down and/or reverse the aging process! (selfgrowth.com)
- New research has identified a natural compound found in many types of fruit, such as apples and strawberries, and vegetables that can slow down the aging process. (medicalnewstoday.com)
- One key factor in the aging process is known as " cellular senescence ," or the aging of the cell. (medicalnewstoday.com)
- In a previous study published in Nature Medicine , scientists at the University of Minnesota Medical School in Minneapolis and the Mayo Clinic in Rochester, MN, noticed that senolytics - which are molecules that target and destroy senescent cells to slow down or prevent the aging process - can effectively prolong an individual's lifespan and improve their health. (medicalnewstoday.com)
- Free radicals are unstable atoms that can cause damage to cells and lead to illnesses and the aging process. (medicalnewstoday.com)
- Beef aging (American English) or ageing is a process of preparing beef for consumption by aging it, in order to break down the connective tissue within the meat. (wikipedia.org)
- Moreover, only the higher grades of meat can be dry aged, as the process requires meat with a large, evenly distributed fat content. (wikipedia.org)
- The process of dry-aging usually also promotes growth of certain fungal (mold) species on the external surface of the meat. (wikipedia.org)
- Dry-aged beef is typically not sold by most supermarkets in the U.S. today, because it takes time and there is a significant loss of weight during the aging process. (wikipedia.org)
- In this context, a material, usually paper, is subjected to extreme conditions in an effort to speed up the natural aging process. (wikipedia.org)
Adults27
- Approximately 25% of U.S. adults 18 years of age and older reported providing care or assistance to a person with a long-term illness or disability in the past 30 days, according to 2009 data from CDC's state-based Behavioral Risk Factor Surveillance System. (cdc.gov)
- Today, NAPCA continues to be the voice of AAPI older adults and their families as leaders in the areas of healthy aging, mature workers, and the prevention of elder abuse. (napca.org)
- With the aging of the AAPI senior population, this implies that many AAPI older adults will either enter or remain in the labor force. (napca.org)
- [15] Furthermore, the older adults' performances in free recall involved temporal contiguity to a lesser extent than for younger people, indicating that associations regarding contiguity become weaker with age. (wikipedia.org)
- [ 6 ] With the growing population of older adults, the role of an elder in the society should be expanded, to enrich and give meaning to lives of its aging citizens. (medscape.com)
- The curriculum includes analysis of aging issues and using design thinking to develop proposals to help older adults in the community. (hawaii.edu)
- The random dial, telephone survey of 859 participants asked middle-aged and older adults about their volunteer experiences, their plans to increase time spent in volunteering, things that motivated them to volunteer, and things that might discourage them from volunteering. (hawaii.edu)
- Middle-aged and older adults can be especially regarded as valuable assets because they have many years of life experience and wisdom to share. (hawaii.edu)
- For example, since 1988, Independent Sector in Washington, DC has done five biennial national surveys of giving and volunteering behaviors of adults 18 years of age and older. (hawaii.edu)
- The findings from this study become the baseline data for Hawaii for middle aged and older adults. (hawaii.edu)
- Services are coordinated and funded through Indiana's network of Area Agencies on Aging and include the state-funded CHOICE program (Community and Home Options to Institutional Care for the Elderly and Disabled) and administration of two Medicaid waiver programs providing home- and community-based services for older adults and individuals of all ages with physical impairments. (in.gov)
- Adult foster homes offer a less expensive, more home-like atmosphere for aging adults than larger facilities. (pbs.org)
- After making it through the maelstrom of middle age, many adults find themselves approaching older age wondering "what will give purpose to my life? (orlandosentinel.com)
- Aging Care Connections' mission is to enrich the quality of life in our community by providing older adults and their families with guidance and support that enhances the ability to age well. (idealist.org)
- We provide comprehensive, coordinated, culturally appropriate long-term health and social services to some of the Bay Area's most vulnerable frail seniors and other adults with disabilities, to help them age in place and prevent more costly health care interventions such as emergency room visits, hospitalizations and premature nursing home placement. (idealist.org)
- The name change also comes in response to the growing population of adults aged 65 and over and their demand for age-related services. (prweb.com)
- Aging Life Care™ / geriatric care management is a holistic, client-centered approach to caring for older adults or others facing ongoing health challenges. (prweb.com)
- Aging Life Care Professionals™ have extensive training and experience working with older adults, people with disabilities, and families who need assistance with caregiving issues. (prweb.com)
- Missoula Aging Services promotes the independence, dignity and health of older adults and those who care for them. (eventbrite.com)
- Unlike a "control group" of adults who did not get regular exercise , the cyclists did not have loss of muscle mass or strength, did not have age-related increases in body fat or cholesterol levels , and their immune systems were as robust as much younger people. (webmd.com)
- BGSU's Optimal Aging Institute (OAI) was created in 2016 to help middle-aged and older adults, and those who work with them, explore the eight dimensions of health, wellness and resiliency. (bgsu.edu)
- 3 Provide learning opportunities and educational materials focusing on optimal aging for service providers, health systems, entrepreneurs, corporations, caregivers, and older adults. (bgsu.edu)
- Bowling Green State University's Optimal Aging Institute, the Area Office on Aging of Northwestern Ohio, Inc. and the Wood County Committee on Aging discuss the impact of the opioid crisis on middle-aged and older adults including grandparents who are raising the children of the opioid epidemic. (bgsu.edu)
- Her research interests include mixed methodology as well as the social aspects of health and community living among older adults with a specific emphasis on social isolation, aging with lifelong disability. (constantcontact.com)
- This conference is intended for adults with an Asperger or related profile who are age 50+. (constantcontact.com)
- Just like younger adults, aging adults should pick up the weights and engage in strength training types of workouts on a regular basis-2-3 times per week. (philly.com)
- We all want to be strong, independent and fully functioning adults as we age into our 60s, 70s, 80s and beyond. (philly.com)
Dementia2
- An aging physician refusing to comply with a new form or yelling at a clerk once when asked to learn a new electronic medical record are inappropriate though not specific assessments for dementia. (medscape.com)
- The promising new approach could produce many new drugs that combat aging, including diseases like Dementia, Alzheimer's, Stroke and others. (medicalnewstoday.com)
Phenotype2
- Accordingly, model animals in which a disruption of a single gene leads to the premature phenotype are useful and indispensable for aging studies. (pnas.org)
- Upon directed differentiation of Progeria-derived iPS cells into smooth muscle cells the premature aging phenotype, including misshapen nuclei, the loss of gene silencing marks and compromised proliferation, reappeared. (newswise.com)
Disability Resource Center2
- The project examines the feasibility of integrating TCARE within the Aging and Disability Resource Center model in the state of Hawaiʻi. (hawaii.edu)
- The North Central Community Choices regional Aging & Disability Resource Center (ADRC) became the first Connecticut ADRC to pilot a Care Transition model that is directly connected an ADRC. (ct.gov)
Younger3
- Even at that age, she makes lots of younger women jealous, and turns men's heads wherever she goes. (webpronews.com)
- According to more detailed Eurostat data, 17.4% of Europeans are aged 65 and over, 16.7% are children aged 14 and younger, and 65.8% are working-age people (aged 15 to 64), but even these numbers are averages, and don't give the full, nuanced picture. (eurekalert.org)
- Whether it's a few years or a solid decade out, if you've caught yourself feeling younger than your biological age, you're not alone. (telegraph.co.uk)
Older27
- For data on the lives of older Americans and their families, see Older Americans 2008: Key Indicators of Well-Being from the Federal Interagency Forum on Aging-Related Statistics. (asha.org)
- By 2030, the number of Americans age 65 and over is projected to reach some 71.5 million people, and nearly 10 million of them will be age 85 and older. (psychologytoday.com)
- The Economics Of Aging Program involves research on the health and economic circumstances of individuals as they age, and on the implications of population aging on the well-being of older persons. (nber.org)
- The underlying focus of the program is the study of the health and financial well-being of people as they age, and the larger implications of a population that is increasingly composed of older people. (nber.org)
- In just the next 20 years, the U.S. population aged 65 and older is projected to increase from 43 million to 76 million people. (nber.org)
- Health affects one's ability to work at older ages, and is strongly associated with financial well-being. (nber.org)
- As the population ages and older workers are making up more and more of the labor force, some employers are taking notice and adjusting their own practices to retain valuable experience and skills. (pbs.org)
- The employment rate of older workers was calculated by dividing the number of employed people between the ages of 55 and 64 by the total population of the same age. (bc.edu)
- Reproduction concerns not only the young and restless - Aging in the Wild takes a light-hearted look at the issue of sexuality and camaraderie in older animals. (cbc.ca)
- One is the imminent arrival in the older age brackets of the large number of people born in the immediate aftermath of World War II-the baby-boom generation, as it is less-than-attractively called. (britannica.com)
- The age-65-and-older population in the U.S. grew by 18 percent between 2000 and 2011 to 41.4 million senior citizens. (huffingtonpost.com)
- This Safety Advisor explores the effects of aging on pilot performance and ways to keep flying safely as we grow older. (aopa.org)
- Older pilots tend to have accumulated more experience and wisdom during the years, and this helps offset certain age-related issues. (aopa.org)
- For example, a smoker who has hypertension and a family history of heart disease is in reality more likely to perform at an age many years older than his or her chronological age. (aopa.org)
- Parsons School of Design and AARP's "Disrupt Aging Design Challenge" asks students to design solutions for older clients. (metropolismag.com)
- The Harris County Area Agency on Aging (HCAAA) is part of a nationwide network coordinating supportive services for the elderly as mandated by the Older Americans Act of 1965 and its subsequent amendments. (houstontx.gov)
- Reports from the CDC suggest that a significant number of new cases of HIV are occurring in people aged 50 or older. (thebody.com)
- According to figures supplied by the Public Health Agency of Canada (PHAC), about 18% of new HIV cases are occurring among people aged 50 or older. (thebody.com)
- The effect of these two trends -- living longer with HIV and new HIV infections occurring at an older age -- will have implications for research. (thebody.com)
- While all five countries share the prospect of an older population, variations in the size and timing of demographic change, as well as important differences in the structure of public programs for the elderly, suggest that population aging will have widely different implications in each country. (google.com)
- Maybe it's just about all of us middle aged folks getting older ourselves. (forbes.com)
- Persons aged 65 years and older constitute the fastest growing segment of our population. (jhu.edu)
- Between 1950 and 1980, the size of this age group doubled from 12.3 million to 25.5 million, and the "very old" age group, those 85 years and older, experienced a 281 percent increase to become 2.2 million. (jhu.edu)
- In 1995, it was estimated that 33.6 million Americans were aged 65 years and older, 3.6 million of whom were at least 85 years old, and 54,000 were centenarians. (jhu.edu)
- By 2050, overall there will be an estimated 78.8 million Americans in the 65 years and over age category, representing 21 percent of the population.1 Most older Americans are women. (jhu.edu)
- that will change to one in four as the number of persons aged 65 years and older increases. (jhu.edu)
- Heart disease and cancer account for 60 percent of the deaths in persons aged 65 years and older. (jhu.edu)
INconnect Alliance1
- The Division of Aging supports the development of alternatives to nursing home care and coordinates services through the statewide INconnect Alliance network. (in.gov)
Processes4
- Aging (senescence) has long been a difficult issue to be experimentally analyzed because of stochastic processes, which contrast with the programmed events during early development. (pnas.org)
- what we see are the processes by which animals reach old age. (cbc.ca)
- Some of the scientists involved in this study - including Prof. Paul D. Robbins, from the University of Minnesota - teamed up again in order to try to identify which senolytics would be the most effective in slowing down aging processes. (medicalnewstoday.com)
- Accelerated aging is testing that uses aggravated conditions of heat, humidity, oxygen, sunlight, vibration, etc. to speed up the normal aging processes of items. (wikipedia.org)
Cellular7
- The complexity of aging has led to a plethora of ideas about the specific molecular and cellular causes and how these alterations lead to age-associated diseases, such as epithelial cancers. (springer.com)
- The level of investigative activity into the mechanisms of aging at the cellular and molecular level has increased dramatically during the past two to three decades. (springer.com)
- Investigative efforts in the area of cellular aging address a number of questions, the answers to which are only beginning to emerge. (springer.com)
- Also, the role of aging at the cellular level in the pathogenesis of age-associated diseases, such as arteriosclerotic vascular disease and many carcinomas, remain, for the most part, speculative. (springer.com)
- While definitive answers to the questions posed above are not forthcoming at the present time, there is enough information to permit some speculation about future directions that may be pursued in the area of cellular aging. (springer.com)
- In this chapter, the current status of cellular aging will be discussed at a level that will provide geriatricians with a foundation of knowledge to assist them in following future developments in the field of basic gerontology. (springer.com)
- Schneider EL, Mitsui Y. The relationship between in vitro cellular aging and in vivo human age. (springer.com)
Lifespan3
- In spite of the fact that the high degree of variability in lifespan across species strongly supports the concept that aging is under genetic control, all three of these theories essentially define senescence as beyond direct regulation by natural selection. (google.com)
- Targeting the genes that control aging not only increases lifespan but seems to improve overall health-so that the animals remain vital as they live longer. (aarp.org)
- When treating aging mice with fisetin, the team saw that it reduced the levels of senescent cells in the animals, prolonging their lifespan and contributing to better health. (medicalnewstoday.com)
Diseases4
- If safety systems fail, aging reactors could leak radiation, which may contaminate the water supply and cause life-threatening diseases and infections. (wired.com)
- So some scientists think a drug that targets one of those genes might amp up the repair work and thus help prevent or treat a host of age-related diseases like diabetes or heart disease. (aarp.org)
- Earlier this year, a group at Pfizer published a study challenging the research that became the cornerstone of Sirtris, a high-profile company that is developing compounds to treat or prevent the diseases of aging. (technologyreview.com)
- Understanding how resveratrol works would move pharmacists forwards into the possibilities of an anti-aging drug, although most people would probably prefer to pop a cork rather than a bottle of pills, there are many diseases such as alzheimer's that could potentially be retarded with more focused treatment. (medicalnewstoday.com)
Health22
- Our study is the first to conclusively demonstrate that inadequate sleep is correlated with reduced skin health and accelerates skin aging. (huffingtonpost.com)
- What Is an Age-Friendly Health System? (ihi.org)
- Accelerate your adoption of the 4Ms in a virtual community with other health systems and be recognized as an Age-Friendly Health System. (ihi.org)
- The Division of Aging Biology (DAB) of the NIA funds Nathan Shock Centers of Excellence in the Basic Biology of Aging across the U.S. There are currently 5 funded Centers, in Maine (The Jackson Laboratory), Michigan (University of Michigan), Texas (University of Texas Health Sciences Center in San Antonio), Washington (University of Washington) and New York (Albert Einstein College of Medicine). (nih.gov)
- What to Expect in your 50's, 60's, and 70's As we age, our health needs are constantly changing. (ageinplace.org)
- How much exercise you need depends on your age and health. (medlineplus.gov)
- Major Goal: Consultants for the Honolulu as an Age-Friendly City Initiative, backed by the Mayor and World Health Organization. (hawaii.edu)
- The landscape of health and health care is changing rapidly as well, with lower disability rates by age, continuing advances in medical technology and disease management, increases in health care costs, and significant reforms in health policy. (nber.org)
- Mental health issues such as depression and anxiety are NOT a normal part of aging and are hard to discuss, diagnose and treat. (slideshare.net)
- Choice In Aging is one of the oldest and most innovative providers of coordinated health and social services for frail seniors and others with disabilities in the Bay Area. (idealist.org)
- As we age, the repair team slacks off and our health deteriorates. (aarp.org)
- AoA was created by Title II of the OAA, and is currently directed by the assistant secretary for aging within the office of the secretary of the Department of Health and Human Services (DHHS). (encyclopedia.com)
- The AOA has information for health professionals, caregivers, and for elders and families on a variety of aging-related topics. (acog.org)
- It includes information on the field of geriatrics as well as links to a physician finder tool and information on aging-related health topics. (acog.org)
- This is a service that helps find programs for people ages 55 and over that may pay for some of their costs of prescription drugs, health care, utilities, food, and other essential items or services. (acog.org)
- This CDC website has information on a variety of health and aging-related topics, including emergency preparedness, preventive care, advance care planning, chronic disease management, and more. (acog.org)
- This site for consumers from the National Library of Medicine includes information on senior health and links to other MedlinePlus pages on aging-related topics. (acog.org)
- This website from the National Institutes of Health presents aging-related health information for consumers on topics such as cancer, memory and mental health, vision and hearing, and many more. (acog.org)
- This comprehensive guide provides information on various health and lifestyle subjects associated with aging and old age. (buzzle.com)
- The 'Wear and Tear' theory of aging suggests that our health deteriorates due to usage and other external factors, similar to how the value of machinery depreciates. (buzzle.com)
- 1 Become recognized as an educational institution that focuses on optimal aging (with a special emphasis on health, wellness, and preventative care). (bgsu.edu)
- I'm a California girl, born and raised here, with an abiding interest in health issues and particularly, healthy aging. (forbes.com)
20161
- The vacuum packed beef is stored at a temperature of 32 °F to 45 °F (0 °C to 7.2 °C). Food portal Ham, especially country ham: pork aging, Bacon Meat hanging Leone, Brad (16 March 2016). (wikipedia.org)
Alzheimer's4
- Age-related memory loss , sometimes described as "normal aging ", is qualitatively different from memory loss associated with dementias such as Alzheimer's disease , and is believed to have a different brain mechanism. (wikipedia.org)
- According to recent research, MCI is seen as the transitional state between cognitive changes of normal aging and Alzheimer's disease. (wikipedia.org)
- The ADEAR website helps users find Alzheimer's disease information and resources from the National Institute on Aging. (acog.org)
- The website of this NIH agency includes publications for consumers, information on Alzheimer's disease, clinical trials, and organizations related to aging. (acog.org)
Biological2
- Goldstein S. Human genetic disorders that feature premature onset and accelerated progression of biological aging. (springer.com)
- Aging is an accumulation of biological changes over a period of time. (buzzle.com)
Physiological4
- This essay deals mainly with physiological but not extensively the structural changes that take place in the gastrointestinal system with aging. (angelfire.com)
- Experience with developing assays of physiological age. (springer.com)
- Aging typically causes weakness, increased susceptibility to disease and infection, loss of mobility and agility, and age-related physiological changes, such as wrinkled skin and gray hair. (news24.com)
- Therefore we are very keen on using our in vitro iPS cell-based model to identify new aging markers and explore other aspects of human premature and physiological aging. (newswise.com)
People21
- What else did people in the Middle Ages know about gravity? (physicsforums.com)
- I have read that in the Middle Ages people believed that angels pushed the Moon in its orbit, the angelic push presumably being in a tangential direction as per the Aristotelian belief that a force is needed to push an object in its direction of motion. (physicsforums.com)
- Mild cognitive impairment (MCI) is a condition in which people face memory problems more often than that of the average person their age. (wikipedia.org)
- Noteworthy people who had the surgery included Harold McCormick, chairman of the board of International Harvester Company, and the aging premier of Turkey. (wikipedia.org)
- While working later in life may seem prudent financially, most people do not continue to work past the typical retirement age. (psychologytoday.com)
- Since the publication of the Origin of the Species, many people have attempted to identify the fundamental causes of aging. (google.com)
- The European Union reports increasing rates of participation in the labor force by people between the ages of 55 and 64. (bc.edu)
- Here at Choice In Aging we are working hard to "promote dignity and independence of people with disabilities and special needs" by removing barriers to independence. (idealist.org)
- In the United States, about two-thirds of people age 65 and over take medications for various conditions. (news24.com)
- But people like Appel seem to have a knack for graceful aging. (medicinenet.com)
- At age 80 people generally have about 50% to 60% of the muscle mass they had when they were 30. (medicinenet.com)
- We find that people who age successfully and have a good quality of life adapt well to changes,' Mosqueda says. (medicinenet.com)
- The largest of the grant programs is Title III, State and Community Programs, through which AoA works closely with a network of 9 federal regional offices, 57 state units on aging, 661 substate area agencies on aging, 228 Native American, Alaskan, and Hawaiian tribal organizations, and some 27,000 providers of services to elderly people. (encyclopedia.com)
- Ages are colour coded: yellow stands for the elderly, pink for children, and blue for working-age people. (eurekalert.org)
- For example, Eastern Europe, particularly Poland and Slovakia, have large working-age populations (marked in turquoise and blue), in sharp contrast to the neighbouring Germany which has a high concentration of elderly people in its eastern part near the border with Poland. (eurekalert.org)
- The Derek Zoolander Center for People Who Don't Age Good (DZCFPWDAG), a state-of-the-art, anti-aging center in New York City opens today at 4 pm. (blogher.com)
- But how can design build stronger bonds between people of all ages? (metropolismag.com)
- Furthermore, the CDC has forecasted that by the year 2020, more than 50% of HIV-positive people in the U.S. will be over the age of 50. (thebody.com)
- It is not just the aging of people with longstanding HIV that is occurring. (thebody.com)
- It is possible that as HIV-positive people age similar dose adjustments may be required. (thebody.com)
- The burden of coping with multiple conditions may be difficult for some people as they strive to remain high functioning and yet are constrained by the effects of aging. (thebody.com)
Americans2
Humans3
- His own research program is nothing if not ambitious: He wants to reverse aging in humans. (nautil.us)
- In this session, a novel mouse mutant, designated klotho (the name of the Greek goddess who spins the thread of life), was presented to exhibit premature aging similar to that in humans (Fig. 1 ). (pnas.org)
- Changes You Can Expect as Your Dog Ages BowWOW Here's how your mature dog's age translates into human years: Appropriate Age in Years Equivalent Age in Humans 5 40 6 45 7 50 8 55 9 61 10 66 11 72 12 77 13 82 14 88 15 93 16 99 Change is a normal. (familyeducation.com)
Caregivers3
- According to the National Alliance for Caregiving (NAC), there are 44 million family caregivers, which is nearly 20 percent of the adult population in the U.S. These caregivers, who are often over the age of 50, provide physical and financial assistance to their elderly loved ones-the NAC also found that while women provide the lion's share of basic care, men also provide financial assistance. (psychologytoday.com)
- Councils on Aging (COAs) are the community focal point for social and support services to elders, families and caregivers in 349 cities and towns in Massachusetts. (mass.gov)
- Caregivers helping an aging parent may be recruited to care for a pet right along with caring for its owner. (forbes.com)
Organismal3
- Underlying all of these theories is the assumption that aging occurs from the bottom-up, beginning with damage to DNA and proteins and ending with organismal frailty, disability, and disease. (springer.com)
- Campisi J (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. (springer.com)
- In the session, Aging Mechanisms , two topics were discussed: first is aging at the organismal level, which is genetically determined, and the second focused on the mechanisms by which cells know when to stop their proliferation. (pnas.org)
Elderly4
- Age-associated epithelial cancers, such as breast cancer , colon cancer, and prostate cancer , however, contribute significantly to the morbidity and mortality of the elderly and are the second leading cause of death. (springer.com)
- There are many organizations dedicated to research on aging, advocating for the elderly, and promoting healthy aging. (asha.org)
- As such, it is charged with providing leadership within the aging network of state and area agencies and of service providers for the elderly, and with coordinating activities of other federal agencies involved with aging. (encyclopedia.com)
- With the Area Agency on Aging acting as an advocate, awareness of the needs of the elderly increases through services that assist the elderly and their families with options that promote independence, well-being and dignity. (houstontx.gov)
Biomarkers1
- Biomarkers of Aging. (springer.com)
Dysfunction3
- The dysfunction address of age to buy viagra research is doctor well better and to a direct left- online as looked at than major uses. (topfishinggames.com)
- Most middle-age men don't have erectile dysfunction, but their erections change, often causing consternation. (psychologytoday.com)
- In addition, it has been suggested, but not proven, that cross-linking of proteins in the walls of arteries or the kidneys may be partly responsible for hardening of the arteries (atherosclerosis) and age-related kidney dysfunction. (news24.com)
Skin elasticity1
- As we age, our skin elasticity starts to deplete, thus leading to sagging skin. (buzzle.com)
Creams3
- It's not surprising that this demographic is often bombarded by the media with anti-aging everything: skin creams for every part of our bodies, miracle "cures" for our wrinkles, youthful colors for our hair. (psychcentral.com)
- Creams are usually a good choice for aging skin. (webmd.com)
- Everywhere you turn in the beauty isles of Walmart are signs and advertisements for "anti-aging" creams, and wrinkle reducing makeup. (blogher.com)
Healthy6
- But such differences don't always mean there's a problem, because perfectly healthy kids can have bone ages that differ from their chronological ages. (kidshealth.org)
- What Do We Know about Healthy Aging? (medlineplus.gov)
- The secret to healthy aging? (psychologytoday.com)
- Are the keys to healthy aging hiding in the DNA of animals? (cbc.ca)
- Living a healthy lifestyle as we age not only benefits our bodies, but also our minds. (psychcentral.com)
- Alkaline water: An easy, healthy and proven way to reverse aging. (selfgrowth.com)
Population12
- The population in the United States is aging. (asha.org)
- Speech-language pathologists play an important role in working with this aging population. (asha.org)
- SLPs should take the initiative to learn more about the aging population and prepare for the increased services this group will demand in the future. (asha.org)
- Given the advancing median age of the European population, this trend is welcome. (bc.edu)
- As Figure 1 shows, 47.4 percent of the European Union population between the ages of 55 and 64 are working, but this means that 52.6 percent are not-a serious loss of human capital. (bc.edu)
- In fact, vascular smooth muscle cell senescence also plays a role in advanced arteriosclerosis within the normal aging population. (newswise.com)
- This is the age structure of European population. (eurekalert.org)
- Europe is ageing: according to UN estimates, half the region's population are aged 43 and over. (eurekalert.org)
- This is consistent with the UN data on total fertility rates (TFR, average number of births per woman of fertile age) in this part of Europe, at around 1.3 in Spain, Portugal and Italy, far below the fertility rate of 2.1 required for simple continuation of the population. (eurekalert.org)
- The incidence of cataracts is rising dramatically in Europe as the continent s population ages. (prweb.com)
- The authors report on national demographic trends, examine the current living conditions of the aged population, explain the structure of the retirement system, and offer estimates of future budgetary costs of the public programs. (google.com)
- An aging society is characterized by a growing proportion of the retired to the active working population. (imf.org)
Research15
- This research shows for the first time, that poor sleep quality can accelerate signs of skin aging and weaken the skin's ability to repair itself at night," said Dr. Daniel Yarosh, a senior vice president at The Estée Lauder Companies, in a press release. (huffingtonpost.com)
- The Centers provide leadership in the pursuit of basic research into the biology of aging. (nih.gov)
- What impact will your work have on aging research? (nautil.us)
- However, research on spirituality struggles to maintain a nonsectarian approach to studying spirituality, owing to the highly heated religious preferences of various authors, [ 17 ] which polarize gerontological literature on spirituality, religiosity and aging. (medscape.com)
- Today, the substantive importance of research on aging has never been greater. (nber.org)
- Over the last 28 years, the NBER's Program on the Economics of Aging has helped to transform this field from an exploratory new research area into a well-recognized and influential subfield of the economics profession. (nber.org)
- NIA's recognition of the analytic value of economic research in aging and its support for a highly integrated program of investigators working collaboratively on aging issues was path-breaking. (nber.org)
- This support has been critical to development of the NBER program, the research subfield, and our understanding more generally of people's well-being as they age. (nber.org)
- The NBER's Aging Program continues to be anchored by NIA Center and Program Project grants, and by multiple NIA-funded research projects that are administered under the coordinating umbrella of the program. (nber.org)
- The program has thrived through its history by simultaneously recruiting and inspiring some of the most prominent, established economics scholars along with more emerging scholars to develop a research agenda on economic issues related to aging. (nber.org)
- The program has also been leveraged by substantial research development support provided by NIA, including an NIA-funded training program on the economics of aging and NIA funding for pilot projects. (nber.org)
- The training program alone has supported about 150 investigators, the large majority of whom have developed a long-term research agenda on the economics of aging. (nber.org)
- In research to be published in The Netherlands later this year ( De Lange, Schalk, Van der Heijden, 2013 ), we discuss negative "push" factors that make it hard for aging workers to stay in their jobs. (bc.edu)
- A piece in Nature outlines the rather technical arguments over Sirtris's sirtuin activators and what it might mean for the company and for anti-aging research more broadly. (technologyreview.com)
- New research is showing the properties of a chemical present in red wine, known as resveratrol, does indeed have anti-aging properties. (medicalnewstoday.com)
Increases2
- In addition, the secondary esophageal peristalsis, which constitute a major clearence mechanism for refluxed gastric acid, seems to be evoked less frequently and less consistently, this increases the liklyhood of the occurrence of gastroesophageal reflux with age. (angelfire.com)
- As individuals age, the damage caused by free radicals increases. (news24.com)
Hoosiers2
Connections2
- These connections between sleep and skin aging, now supported with solid scientific data, will have a profound effect on how we study skin and its functions. (huffingtonpost.com)
- In aging, degradation of white matter structure has emerged as an important general factor, further focusing attention on the critical white matter connections. (wikipedia.org)
Healthier1
- Layer over Powerful-Strength Line-Reducing Concentrate for optimal anti-aging and healthier skin benefits. (sephora.com)
Years11
- Suicide is the third leading cause of death among youth 15 through 24 years of age. (cdc.gov)
- The bone age is measured in years. (kidshealth.org)
- During the age work, she tells some years that bob and legally lee sold their consultation to paul, prompting the levitra to attack them. (topfishinggames.com)
- The NBER's Program on the Economics of Aging began in 1986, when the baby boom generation was between the ages of 22 and 40, and when life expectancy at age 62 (the age of eligibility for Social Security) was nearly three years shorter than it is today. (nber.org)
- However, in recent years, many experimental results that contradict this concept by demonstrating increased life-span with increased reproductive capacity leaves this question in aging theory unresolved. (google.com)
- For some years I have been giving thought to the matter of age and aging . (britannica.com)
- Sue and Gigi started an anti-aging beauty blog about 3 years ago then dropped it.Many friends and followers talked us into starting up again, hence, SueAndGigi.com. (blogher.com)
- The "gang-bangers" ranged in age from 14 to 20, and the "hardcores," who were between 18 to 20 and up, with few over 24 or 25 years old. (csun.edu)
- According to Dr Sergei Scherbov, a specialist in demographic analysis: "Two hundred years ago, a 60-year-old would be a very old person, [but] someone who is 60 years old today, I would argue, is middle-aged. (telegraph.co.uk)
- Rafael de Cabo at the National Institute on Aging in Baltimore, Maryland, and a co-author on the 2006 Nature paper, says that he has safely tested one of the compounds, SRT1720, in more than 1,000 mice, some of which received the compound for two years. (technologyreview.com)
- In 1929, a frequently used method in which 72 hours at 100 degrees Celsius is considered equivalent to 18-25 years of natural aging was established by R. H. Rasch. (wikipedia.org)
Center6
- A clinical trial commissioned by Estée Lauder and conducted by physician-scientists at University Hospitals (UH) Case Medical Center found that poor sleepers demonstrated increased signs of skin aging . (huffingtonpost.com)
- A bone age X-ray will be done by an X-ray technician in a radiology department within a hospital, a freestanding radiology center, or doctor's office. (kidshealth.org)
- On November 1, 1979, a small federal grant gave birth to the National Asian Pacific Center on Aging. (napca.org)
- The Mt. Diablo Center and The Bedford Center are programs of Choice in Aging. (idealist.org)
- The UH Center on Aging and Hawaii Pacific Gerontological Society is proud to announce a scholarship for students with a serious interest in a career in aging, long-term care, and/or death and dying. (hawaii.edu)
- Center on Aging, University of Hawaii at Manoa. (hawaii.edu)
Examines1
- The study examines the pension-related aging problem primarily from a fiscal perspective. (imf.org)
Awareness of the needs1
- AoA's second mission is broader, involving promoting awareness of the needs of the aging beyond grant administration, oversight, and evaluation. (encyclopedia.com)
Services2
Populations2
- an alternative notion is that the manifestations of aging are the summation of subtle decrements of function in most or all of the cell populations in the body. (springer.com)
- This paper discusses a study analyzing aging populations and public pension schemes. (imf.org)
Mechanisms2
- However, we have recently started to learn the molecular mechanisms that control aging. (pnas.org)
- Clearly, important additional mechanisms are involved in the regulation of aging. (google.com)
Senescence6
- A family lineage exhibiting progeria (premature aging) indicates that senescence is, at least to some extent, controlled genetically. (pnas.org)
- The klotho gene encodes a novel protein that appears to function outside of the cells (secreted protein), and thus it is very different from that involved in previously described premature-aging syndromes and cell senescence, which function in the nucleus. (pnas.org)
- A theory of aging is proposed challenging the concept that economic trade-offs between body repair and reproduction are the primary drivers of senescence. (google.com)
- Relative to aging theory this has remained problematic because It has not been intuitively obvious how senescence can function as a trait that favors the fitness of the individual. (google.com)
- This paper, "Mate-Selection Scale And Aging" (MSSA) describes an additional significant mechanism of aging and provides the rational for the species specific rates of senescence that we see across species from the very short lived to the negligibly senescent. (google.com)
- The visible signs of old age and fragility, what scientists call senescence, do not always present themselves in the same way. (cbc.ca)
Wisely1
- Let's age wisely by not trying to hold on to the past, or by dwelling on the future. (psychcentral.com)
Study10
- sleep deprivation also could cause your skin to age faster , according to a new study. (huffingtonpost.com)
- The study involved 60 pre-menopausal women between the ages of 30 and 49, with half of them falling into the poor quality sleep category. (huffingtonpost.com)
- A bone age study helps doctors estimate the maturity of a child's skeletal system. (kidshealth.org)
- In particular, associative learning, which is another type of episodic memory, is vulnerable to the effects of aging, and this has been demonstrated across various study paradigms. (wikipedia.org)
- Life extension strategies often study the causes of aging and try to oppose those causes in order to slow aging. (wikipedia.org)
- This study , published in 2012 in The Journal of the American Medical Association, examined the relationship between attitudes about aging and recovery from disabilities. (psychcentral.com)
- This reversible suppression of progerin expression by reprogramming and subsequent reactivation during differentiation, provides a unique model system to study human premature aging pathologies," says Izpisúa Belmonte. (newswise.com)
- In the study, the team assessed 84 male and 41 female cyclists, aged 55 to 79. (webmd.com)
- A study published in the scientific journal Nature has uncovered at least one source of aging among mammals similar to ourselves, and points in the direction of how to stop it. (extremetech.com)
- New study shows that resveratrol reduces age-induced deterioration of neuromuscular synapses in mice. (medicalnewstoday.com)
Mice1
- i ) Despite the fact that klotho mutant mice show systemic aging phenotypes, only limited organs express the klotho gene endogenously. (pnas.org)
Issues3
- It's a serious problem, and it is one of a number of problems that I would call 'aging aircraft' issues that we face with these vehicles,' shuttle program manager Wayne Hale said. (space.com)
- Various issues such as wrinkling, sagging skin, and other problems of aging skin are dealt with on this page. (buzzle.com)
- Now, I'm in the advice and conflict resolution field, focused on issues about aging and aging parents. (forbes.com)
Scientists1
- Last week, a discovery published by scientists at Northwestern University detailed a new genetic switch that may prove to be a watershed in the fight against aging. (extremetech.com)