Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
Individuals' concept of their own bodies.
Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.
An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.
Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.
Removal of dental plaque and dental calculus from the surface of a tooth, from the surface of a tooth apical to the gingival margin accumulated in periodontal pockets, or from the surface coronal to the gingival margin.
A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.
A numerical rating scale for classifying the periodontal status of a person or population with a single figure which takes into consideration prevalence as well as severity of the condition. It is based upon probe measurement of periodontal pockets and on gingival tissue status.
A fluid occurring in minute amounts in the gingival crevice, believed by some authorities to be an inflammatory exudate and by others to cleanse material from the crevice, containing sticky plasma proteins which improve adhesions of the epithelial attachment, have antimicrobial properties, and exert antibody activity. (From Jablonski, Illustrated Dictionary of Dentistry, 1982)
An index which scores the degree of dental plaque accumulation.
A procedure for smoothing of the roughened root surface or cementum of a tooth after subgingival curettage or scaling, as part of periodontal therapy.
The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY.
A family of coccoid to rod-shaped nonsporeforming, gram-negative, nonmotile, facultatively anaerobic bacteria that includes the genera ACTINOBACILLUS; HAEMOPHILUS; MANNHEIMIA; and PASTEURELLA.
Oral tissue surrounding and attached to TEETH.
Those protein complexes or molecular sites on the surfaces and cytoplasm of gonadal cells that bind luteinizing or chorionic gonadotropic hormones and thereby cause the gonadal cells to synthesize and secrete sex steroids. The hormone-receptor complex is internalized from the plasma membrane and initiates steroid synthesis.
Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.
A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
Curved bacteria, usually crescent-shaped rods, with ends often tapered, occurring singly, in pairs, or short chains. They are non-encapsulated, non-sporing, motile, and ferment glucose. Selenomonas are found mainly in the human buccal cavity, the rumen of herbivores, and the cecum of pigs and several rodents. (From Bergey's Manual of Determinative Bacteriology, 9th ed)
Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva. The term is sometimes used in connection with smoothing of a root surface or ROOT PLANING. (Jablonski; Illustrated Dictionary of Dentistry, 1982)
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium is a common commensal in the gingival crevice and is often isolated from cases of gingivitis and other purulent lesions related to the mouth.
Inflammation of the PERIAPICAL TISSUE. It includes general, unspecified, or acute nonsuppurative inflammation. Chronic nonsuppurative inflammation is PERIAPICAL GRANULOMA. Suppurative inflammation is PERIAPICAL ABSCESS.
Infections with bacteria of the genus ACTINOBACILLUS.
Removal or disruption of DENTAL DEPOSITS and plaque-retentive DENTAL CALCULUS from tooth surfaces and within the periodontal pocket space without deliberate removal of CEMENTUM as done in ROOT PLANING and often in DENTAL SCALING. The goal is to conserve dental cementum to help maintain or re-establish healthy periodontal environment and eliminate PERIODONTITIS by using light instrumentation strokes and nonsurgical techniques (e.g., ultrasonic, laser instruments).
Generalized or localized diffuse fibrous overgrowth of the gingival tissue, usually transmitted as an autosomal dominant trait, but some cases are idiopathic and others produced by drugs. The enlarged gingiva is pink, firm, and has a leather-like consistency with a minutely pebbled surface and in severe cases the teeth are almost completely covered and the enlargement projects into the oral vestibule. (Dorland, 28th ed)
A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.
A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Infections with bacteria of the family BACTEROIDACEAE.
Toxins produced, especially by bacterial or fungal cells, and released into the culture medium or environment.
A class of statistical methods applicable to a large set of probability distributions used to test for correlation, location, independence, etc. In most nonparametric statistical tests, the original scores or observations are replaced by another variable containing less information. An important class of nonparametric tests employs the ordinal properties of the data. Another class of tests uses information about whether an observation is above or below some fixed value such as the median, and a third class is based on the frequency of the occurrence of runs in the data. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1284; Corsini, Concise Encyclopedia of Psychology, 1987, p764-5)
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
A species of bacteria in the family SPIROCHAETACEAE, frequently isolated from periodontal pockets (PERIODONTAL POCKET).
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
A subdiscipline of human genetics which entails the reliable prediction of certain human disorders as a function of the lineage and/or genetic makeup of an individual or of any two parents or potential parents.
The systematic study of the complete DNA sequences (GENOME) of organisms.
Decisions, usually developed by government policymakers, for determining present and future objectives pertaining to the health care system.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
The activities and endeavors of the public health services in a community on any level.
The integration of epidemiologic, sociological, economic, and other analytic sciences in the study of health services. Health services research is usually concerned with relationships between need, demand, supply, use, and outcome of health services. The aim of the research is evaluation, particularly in terms of structure, process, output, and outcome. (From Last, Dictionary of Epidemiology, 2d ed)

Humoral immune responses in periodontal disease may have mucosal and systemic immune features. (1/126)

The humoral immune response, especially IgG and IgA, is considered to be protective in the pathogenesis of periodontal disease, but the precise mechanisms are still unknown. Immunoglobulins arriving at the periodontal lesion are from both systemic and local tissue sources. In order to understand better the local immunoglobulin production, we examined biopsy tissue from periodontitis lesions for the expression of IgM, IgG, IgA, IgE and in addition the IgG and IgA subclasses and J-chain by in situ hybridization. Tissues examined were superficial inflamed gingiva and the deeper granulation tissue from periodontal sites. These data confirm that IgM, and IgG and IgA subclass proteins and J-chain can be locally produced in the periodontitis tissues. IgG1 mRNA-expressing cells were predominant in the granulation tissues and in the gingiva, constituting approx. 65% of the total IgG-expressing plasma cells. There was a significantly increased proportion of IgA-expressing plasma cells in the gingiva compared with the granulation tissue (P < 0.01). Most of the IgA-expressing plasma cells were IgA1, but a greater proportion expressed IgA2 mRNA and J-chain mRNA in the gingival tissues (30.5% and 7.5%, respectively) than in the periodontal granulation tissues (19% and 0-4%, respectively). The J-chain or dimeric IgA2-expressing plasma cells were located adjacent to the epithelial cells, suggesting that this tissue demonstrates features consistent with a mucosal immune response. Furthermore, we were able to detect the secretory component in gingival and junctional epithelial cells, demonstrating that the periodontal epithelium shares features with mucosal epithelium. In contrast, deeper tissues had more plasma cells that expressed IgM, and less expressing IgA, a response which appears more akin to the systemic immune response. In conclusion, this study suggests that immune mechanisms involved in the pathogenesis of periodontitis may involve features of both the mucosal and systemic immune systems, dependent on tissue location.  (+info)

Neutrophil dysfunctions, IL-8, and soluble L-selectin plasma levels in rapidly progressive versus adult and localized juvenile periodontitis: variations according to disease severity and microbial flora. (2/126)

We used flow cytometry to analyze the expression of adhesion molecules and the oxidative burst of whole-blood polymorphonuclear neutrophils (PMN) from 26 patients with periodontitis. Three different clinical entities were studied: adult periodontitis (AP), localized juvenile periodontitis (LJP), and rapidly progressive periodontitis (RPP). Unstimulated PMN from the patients showed reduced Lewis x, sialyl-Lewis x, and L-selectin expression relative to those from healthy control subjects. These alterations were present whatever the severity of periodontal disease. However, PMN from RPP patients showed increased basal H2O2 production and decreased L-selectin shedding. These latter impairments, which correlated with increased IL-8 plasma levels, could contribute to initial vascular damage. In addition, decreased IL-8 priming of H2O2 production by PMN from RPP patients could account for a lower bactericidal capacity of PMN, leading to the large number of bacteria in the subgingival region of RPP patients. Soluble L-selectin plasma levels were also decreased in the RPP group, indicating more severe or diffuse endothelial damage. These abnormalities were not found in the patients with less destructive forms of periodontitis (AP and LJP). Porphyromonas gingivalis, a bacterial pathogen known to increase IL-8 production by PMN, was found in the periodontal pockets of RPP patients only. These results show links among PMN abnormalities, the clinical form of periodontitis, and the gingival bacterial flora.  (+info)

Localisation of a gene for prepubertal periodontitis to chromosome 11q14 and identification of a cathepsin C gene mutation. (3/126)

Prepubertal periodontitis (PPP) is a rare and rapidly progressive disease of young children that results in destruction of the periodontal support of the primary dentition. The condition may occur as part of a recognised syndrome or may occur as an isolated finding. Both autosomal dominant and recessive forms of Mendelian transmission have been reported for PPP. We report a consanguineous Jordanian family with four members affected by PPP in two nuclear sibships. The parents of the affected subjects are first cousins. We have localised a gene of major effect for PPP in this kindred (Zmax=3.55 for D11S901 at theta=0.00) to a 14 cM genetic interval on chromosome 11q14 flanked by D11S916 and D11S1367. This PPP candidate interval overlaps the region of chromosome 11q14 that contains the cathepsin C gene responsible for Papillon-Lefevre and Haim-Munk syndromes. Sequence analysis of the cathepsin C gene from PPP affected subjects from this Jordanian family indicated that all were homozygous for a missense mutation (1040A-->G) that changes a tyrosine to a cysteine. All four parents were heterozygous carriers of this Tyr347Cys cathepsin C mutation. None of the family members who were heterozygous carriers for this mutation showed any clinical findings of PPP. None of the 50 controls tested were found to have this Tyr347Cys mutation. This is the first reported gene mutation for non-syndromic periodontitis and shows that non-syndromic PPP is an allelic variant of the type IV palmoplantar ectodermal dysplasias.  (+info)

Regulation of immunoglobulin G2 production by prostaglandin E(2) and platelet-activating factor. (4/126)

Patients with localized juvenile periodontitis (LJP) have elevated levels of immunoglobulin G2 (IgG2) in their sera. This is also observed in vitro when peripheral blood leukocytes from LJP patients are stimulated with pokeweed mitogen. In previous studies, we showed that lymphocytes from subjects with no periodontitis (NP subjects) produced substantial amounts of IgG2 when they were cultured with monocytes from LJP patients (LJP monocytes). These observations indicate that monocytes or monocyte-derived mediators are positive regulators of the production of IgG2. The present study was initiated to determine if secreted factors from LJP monocytes were capable of enhancing IgG2 production and to determine if prostaglandin E2 (PGE(2)), which LJP monocytes produce at elevated levels, enhances IgG2 production. Experiments in a transwell system and with monocyte-conditioned media indicated that cell-cell contact was not necessary for LJP monocytes to augment the production of IgG2 by T and B cells from NP subjects. Moreover, the production of IgG2 was selectively induced by the addition of PGE(2) or platelet-activating factor (PAF), another lipid cytokine, which can elevate PGE(2) synthesis. Furthermore, IgG2 production was abrogated when cells were treated with indomethacin, a cyclooxygenase inhibitor that blocks the synthesis of PGE(2), or the PAF antagonists CV3988 and TEPC-15. The effects of indomethacin were completely reversed by PGE(2), indicating that this is the only prostanoid that is essential for the production of IgG2. Similarly, PGE(2) reversed the effects of a PAF antagonist, suggesting that the effects of PAF are mediated through the induction of PGE(2) synthesis. Together, these data indicate that PGE(2) and PAF are essential for the production of IgG2.  (+info)

Th1 and Th2 cytokine profile in patients with early onset periodontitis and their healthy siblings. (5/126)

Early onset periodontitis (EOP) is a chronic inflammatory periodontal disease with a strong genetic link affecting individuals aged 17 to 25. In the familial studies we tested the hypothesis about the role of Th1 and Th2 cytokines in the pathogenesis of EOP disease. The study involved 6 individuals with EOP disease and their 6 siblings with healthy periodontium. Actinobacillus actinomycetemcomitans (A. a), a bacterium typical for EOP, was detected in all people studied. Th1 and Th2 cytokine production was measured after in vitro stimulation. Peripheral blood mononuclear cells (PBMC) were isolated and cultivated for 24 h and 7 days with PWM, A. a. or Escherichia coli. The levels of IL-4, IFN-gamma, IgA, IgG and IgM were measured by ELISA methods. After in vitro stimulation of PBMC, a significantly higher production of IL-4 and significantly lower production of IFN-gamma were found in the group of patients compared with their healthy siblings. The increased level of IL-4 in patients was in good agreement with an increased level of IgM after stimulation of lymphocytes with E. coli. These results support Seymour's hypothesis according to which patients with progressive disease primarily activate Th2 lymphocytes while non-susceptible individuals activate Th1 lymphocytes.  (+info)

Beyond the specific plaque hypothesis: are highly leukotoxic strains of Actinobacillus actinomycetemcomitans a paradigm for periodontal pathogenesis? (6/126)

Actinobacillus actinomycetemcomitans is a facultative anaerobe implicated in a variety of periodontal diseases. Its presence is most closely associated with localized juvenile periodontitis (LIP), although the exact role of the organism in this and other periodontal diseases is not entirely clear. While A. actinomycetemcomitans produces several different putative virulence factors, the most widely studied is the leukotoxin. The leukotoxin selectively kills polymorphonuclear leukocytes and macrophages in vitro, constituting the host's first line of defense. Interestingly, even though all strains of A. actinomycetemcomitans have the genes encoding the leukotoxin, there is variability in leukotoxin expression. Differences in the structure of the promoter region of the leukotoxin gene operon were shown to correlate directly with levels of leukotoxin production. Highly leukotoxic forms appear to exhibit increased pathogenic potential, as evidenced by recent studies that have shown a significant association between the prevalence of such strains and the occurrence of LIP in several different populations. This represents the first demonstration of an association between a particular subset of a pathogenic species and a specific periodontal disease. Early identification of A. actinomycetemcomitans by microbial and genetic assays to evaluate leukotoxicity may enhance the efficacy of preventive and/or therapeutic techniques. Future investigations should continue to evaluate pathogenic variations of additional virulence factors expressed in vivo, not only of A. actinomycetemcomitans, but also of other periodontal bacteria and infectious disease pathogens.  (+info)

Defective Gi protein coupling in two formyl peptide receptor mutants associated with localized juvenile periodontitis. (7/126)

The formyl peptide receptor (FPR) is a prototypical chemoattractant receptor expressed in neutrophils. It is well known that the FPR couples to G(i) proteins to activate phospholipase C, chemotaxis, and cytotoxic cell functions, but the in vivo role of the FPR in man has remained elusive. Recently, F110S and C126W mutations of the FPR have been associated with localized juvenile periodontitis. We studied FPR-F110S and FPR-C126W in comparison with wild-type FPR (FPR-WT) by coexpressing epitope-tagged versions of these receptors with the G protein Galpha(i2)beta(1)gamma(2) in Sf9 insect cells. FPRs were efficiently expressed in Sf9 membranes as assessed by immunoblotting using the beta(2)-adrenoreceptor as a standard. FPR-C126W differed from FPR-WT and FPR-F110S in migration on SDS-polyacrylamide gels and tunicamycin-sensitive glycosylation. FPR-WT efficiently reconstituted high-affinity agonist binding and agonist- and inverse agonist-regulated guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS) binding to Galpha(i2)beta(1)gamma(2). In contrast, FPR-F110S only weakly reconstituted agonist-stimulated GTPgammaS binding, and FPR-C126W was completely inefficient. Collectively, our data show almost complete and complete loss of G(i) protein coupling in FPR-F110S and FPR-C126W, respectively. The severe functional defects in FPR-F110S and FPR-C126W contrast with the discrete clinical symptoms associated with these mutations, indicating that loss of FPR function in host defense is, for the most part, readily compensated.  (+info)

Population structure and genetic diversity of Actinobacillus actinomycetemcomitans strains isolated from localized juvenile periodontitis patients. (8/126)

The phylogeny of 20 Actinobacillus actinomycetemcomitans strains isolated from patients with localized juvenile periodontitis (LJP) was investigated by using partial sequence analysis of 16S rRNA genes, arbitrarily primed PCR (AP-PCR), and four additional PCR assays that amplified polymorphic regions in the leukotoxin (lkt), cytolethal distending toxin (cdt), major fimbrial subunit (flp-1), and serotype-specific O polysaccharide gene clusters. Our analysis also included four strains isolated from healthy subjects and nine reference strains. We found that A. actinomycetemcomitans strains comprised three major phylogenetic lineages. One lineage consisted of serotype b strains, a second lineage consisted of serotype c strains, and a third lineage consisted of serotype a, d, e, and f strains. 16S rRNA sequences within each lineage were highly conserved (<1% base substitutions), whereas sequences between lineages were exceptionally divergent (1.9 to 5.0% substitutions). Two strains exhibited 16S rRNA sequences that were even more distantly related to those of the three major lineages (2.7 to 6.7% substitutions), indicating that additional minor lineages or variants exist. The distribution of 16S rRNA sequences and lkt, cdt, flp-1, and AP-PCR genotypes was consistent with a clonal population structure, with little evidence of assortative recombination between strains of different serotypes. Strains from all three major lineages were recovered from LJP patients, suggesting that phylogenetically diverse strains of A. actinomycetemcomitans carry pathogenic potential.  (+info)

The exact cause of aggressive periodontitis is not fully understood, but it is believed to be linked to factors such as genetics, smoking, and poor oral hygiene. Treatment options include antibiotics, surgical therapy, and lifestyle changes such as improved oral hygiene and quitting smoking.

A more detailed definition of aggressive periodontitis is: "An acute or chronic form of periodontitis that is characterized by rapid attachment loss, bone destruction, exuberant inflammation, and pain, and often affects young adults who are otherwise healthy. The condition can lead to tooth loss if left untreated."

Causes and risk factors:

* Poor oral hygiene
* Smoking
* Genetics
* Hormonal changes
* Malnutrition
* Diabetes
* Obesity


* Gum redness, swelling, and bleeding
* Pockets between the teeth and gums
* Bad breath
* Loose teeth or teeth that have moved out of their sockets
* Changes in the shape of the gum line


* Physical examination of the teeth and gums
* X-rays or other imaging tests to assess bone loss and other changes
* Blood tests to check for underlying conditions such as diabetes or cardiovascular disease


* Professional scaling and root planing (a deep cleaning of the teeth)
* Antibiotics to control infection
* Surgery to remove infected tissue or repair damaged bone
* Changes to oral hygiene habits, such as brushing and flossing more frequently


* Good oral hygiene practices such as brushing and flossing regularly
* Regular dental check-ups and cleanings
* Avoiding smoking and other harmful habits
* Maintaining a healthy diet and getting enough exercise


* With proper treatment and good oral hygiene, the condition can be managed and teeth can be saved.
* Without treatment, the condition can progress and lead to tooth loss.


* Tooth loss
* Bone loss
* Infection of other parts of the body (sepsis)
* Heart disease
* Stroke

Note: This definition is a general overview of chronic periodontitis and is not intended to be a substitute for professional medical advice. If you suspect you have chronic periodontitis, it is important to consult with a dentist or other qualified healthcare professional for an accurate diagnosis and appropriate treatment.

It is common for people with poor oral hygiene habits, smokers or those with systemic diseases such as diabetes or heart disease to experience periodontal attachment loss. It can also be a consequence of aging, as the supporting bone and gum tissue around the teeth can degenerate over time.

There are several risk factors for periodontal attachment loss, including:

* Poor oral hygiene habits
* Smoking
* Systemic diseases such as diabetes or heart disease
* Genetic predisposition
* Poor diet
* Inadequate salivary flow
* Malocclusion (bad bite)

There are several treatment options available for periodontal attachment loss, including:

* Scaling and root planing (a deep cleaning of the teeth and beneath the gum line)
* Guided tissue regeneration (a surgical procedure to promote new bone growth)
* Bone grafting (a surgical procedure to repair or replace damaged bone)
* Dental implants (artificial tooth roots that are placed in the jawbone to support a dental crown or bridge)

It is important to note that periodontal attachment loss can be prevented with proper oral hygiene habits, regular dental check-ups and prompt treatment of any oral health issues.

Here are some common causes of gingival hemorrhage:

1. Poor oral hygiene: When you don't brush and floss regularly, plaque and tartar can build up along the gum line, leading to inflammation and bleeding.
2. Gingivitis: This is an early stage of gum disease that can cause swollen, red gums that bleed easily.
3. Periodontitis: This is a more advanced stage of gum disease that can cause the gums to pull away from the teeth and create pockets where bacteria can grow, leading to bleeding.
4. Injury to the gums: If you accidentally bite your lip or tongue, or if you have a sharp object pierce your gum, it can cause bleeding.
5. Medications: Certain medications such as aspirin, warfarin, and prednisone can thin the blood and increase the risk of gingival hemorrhage.
6. Hormonal changes: Changes in hormone levels during pregnancy, menstruation, or menopause can increase the risk of gingival hemorrhage.
7. Vitamin deficiencies: Deficiencies in vitamins such as vitamin C and K can impair the body's ability to clot blood and increase the risk of bleeding gums.
8. Systemic diseases: Certain systemic diseases such as diabetes, rheumatoid arthritis, and liver disease can increase the risk of gingival hemorrhage.

If you experience gingival hemorrhage, your dentist may perform a thorough examination to determine the underlying cause. Treatment options will depend on the severity of the condition, but may include professional cleaning, antibiotics, or surgery. It is important to maintain good oral hygiene practices and visit your dentist regularly to prevent and manage gingival hemorrhage.

The alveolar bone is a specialized type of bone that forms the socket in which the tooth roots are embedded. It provides support and stability to the teeth and helps maintain the proper position of the teeth in their sockets. When the alveolar bone is lost, the teeth may become loose or even fall out completely.

Alveolar bone loss can be detected through various diagnostic methods such as dental X-rays, CT scans, or MRI scans. Treatment options for alveolar bone loss depend on the underlying cause and may include antibiotics, bone grafting, or tooth extraction.

In the context of dentistry, alveolar bone loss is a common complication of periodontal disease, which is a chronic inflammatory condition that affects the supporting structures of the teeth, including the gums and bone. The bacteria that cause periodontal disease can lead to the destruction of the alveolar bone, resulting in tooth loss.

In addition to periodontal disease, other factors that can contribute to alveolar bone loss include:

* Trauma or injury to the teeth or jaw
* Poorly fitting dentures or other prosthetic devices
* Infections or abscesses in the mouth
* Certain systemic diseases such as osteoporosis or cancer

Overall, alveolar bone loss is a significant issue in dentistry and can have a major impact on the health and function of the teeth and jaw. It is essential to seek professional dental care if symptoms of alveolar bone loss are present to prevent further damage and restore oral health.

Plaque is a key risk factor for dental caries (tooth decay) and periodontal disease, which can lead to tooth loss if left untreated. In addition, research suggests that there may be a link between oral bacteria and certain systemic diseases, such as heart disease and diabetes. Therefore, maintaining good oral hygiene practices, such as regular brushing and flossing, is essential to prevent the accumulation of plaque and promote overall health.

Gingivitis can be treated with good oral hygiene practices, such as brushing and flossing regularly, and by visiting a dentist for regular check-ups and professional cleanings. If left untreated, gingivitis can progress to periodontitis, a more severe form of gum disease that can lead to permanent damage and tooth loss.

Some common symptoms of gingivitis include:

* Red and swollen gums
* Bleeding during brushing or flossing
* Bad breath
* Tenderness or pain in the gums
* A decrease in the amount of saliva

Treatment for gingivitis typically involves a combination of good oral hygiene practices and professional dental care. This may include:

* Regular brushing and flossing to remove plaque and bacteria from the teeth
* Professional cleanings ( scaling and root planing) to remove plaque and tartar from the teeth
* Antibiotics to treat any underlying infections
* Changes to diet and lifestyle to reduce the risk of further irritation to the gums.

It's important to note that while gingivitis is a mild form of gum disease, it can still have serious consequences if left untreated. Regular dental check-ups and good oral hygiene practices are essential for preventing and treating gingivitis.

Symptoms of periapical periodontitis may include:

* Pain or tenderness in the affected tooth
* Swelling and redness in the gum tissue
* Bad breath or a bad taste in the mouth
* Discharge of pus from the affected tooth

Periapical periodontitis is typically diagnosed through a combination of clinical examination and diagnostic tests such as radiographs (x-rays) or dental scans. Treatment may involve antibiotics, a root canal, or extraction of the affected tooth, depending on the severity of the infection and the extent of damage to the pulp and surrounding tissues.


Actinobacillus infections are bacterial infections caused by the Actinobacillus genus of bacteria. These bacteria can cause a range of illnesses, from mild to severe, and can affect various parts of the body, including the skin, respiratory tract, digestive system, and bloodstream.


Actinobacillus infections are typically caused by exposure to contaminated food or water or through contact with an infected animal or person. The bacteria can enter the body through cuts or wounds or through the respiratory tract. People with weakened immune systems, such as those with HIV/AIDS or undergoing chemotherapy, are more susceptible to Actinobacillus infections.


The symptoms of Actinobacillus infections can vary depending on the severity of the infection and the location of the infection. Common symptoms include fever, chills, muscle aches, joint pain, and swollen lymph nodes. In more severe cases, Actinobacillus infections can cause pneumonia, meningitis, or sepsis.


Diagnosis of Actinobacillus infections typically involves a combination of physical examination, medical history, and laboratory tests. Blood cultures, PCR tests, and imaging studies such as X-rays or CT scans may be ordered to confirm the diagnosis and determine the severity of the infection.


The treatment of Actinobacillus infections depends on the severity of the infection and the location of the infection. Mild cases may be treated with antibiotics such as penicillin or amoxicillin, while more severe cases may require hospitalization and intravenous antibiotics. In some cases, surgical drainage of abscesses or removal of infected tissue may be necessary.


Prevention of Actinobacillus infections is key to avoiding the potential complications of these bacterial infections. Practicing good hygiene, such as washing your hands frequently and thoroughly, can help prevent the spread of Actinobacillus infections. Avoiding close contact with people who are sick and covering wounds or cuts can also help prevent infection.


The prognosis for Actinobacillus infections is generally good if treated promptly and effectively. However, in more severe cases or those with underlying medical conditions, the prognosis may be guarded. It is important to seek medical attention immediately if symptoms persist or worsen over time.


Actinobacillus infections can lead to a variety of complications if left untreated or if treatment is delayed. These complications include:

* Abscesses: Actinobacillus infections can cause abscesses, which are pockets of pus that form in response to the infection. Abscesses can be painful and may require surgical drainage.
* Cellulitis: Actinobacillus infections can also cause cellulitis, a more widespread infection of the skin and underlying tissues.
* Sepsis: In severe cases, Actinobacillus infections can lead to sepsis, a life-threatening condition that occurs when the body's response to an infection becomes uncontrolled and causes widespread inflammation.
* Amputations: In some cases, Actinobacillus infections may be so severe that they require amputation of affected limbs or digits.

It is important to seek medical attention immediately if you suspect you have an Actinobacillus infection. With prompt and effective treatment, the prognosis for these infections is generally good. However, delays in treatment can lead to serious complications and long-term consequences.

Gingival fibromatosis is relatively rare and usually does not require treatment unless it becomes inflamed or infected. Treatment options may include antibiotics, surgical removal of the growth, or other methods to reduce inflammation and improve oral hygiene.


* Gingival fibroma
* Pyogenic granuloma
* Peripheral giant cell granuloma
* Fibromatous hyperplasia of the gingiva

Note: The term "fibromatosis" refers to the excessive growth of fibrous tissue, which can occur in various parts of the body. In the context of oral health, it specifically refers to the growth of fibrous tissue on the gums.

Some common types of Bacteroidaceae infections include:

1. Bacteroiditis: This is an infection caused by Bacteroides fragilis, which is a common resident of the human gut microbiome. Bacteroiditis can occur when the bacteria enter the bloodstream or other parts of the body, causing symptoms such as fever, chills, and swelling.
2. Parabacteroides infection: This type of infection is caused by the bacterium Parabacteroides distasonis, which is found in the gut microbiome. Parabacteroides infections can cause a range of symptoms, including diarrhea, abdominal pain, and fever.
3. Chryseobacterium infection: This type of infection is caused by the bacterium Chryseobacterium spp., which is found in the environment and can enter the body through wounds or other openings. Chryseobacterium infections can cause symptoms such as fever, chills, and swelling.

Bacteroidaceae infections can be diagnosed through a variety of tests, including blood cultures, urine cultures, and tissue biopsies. Treatment typically involves the use of antibiotics, and in some cases, surgical intervention may be necessary to remove infected tissue or repair damaged structures.

Preventive measures for Bacteroidaceae infections include good hygiene practices such as handwashing, proper wound care, and avoiding close contact with people who are sick. In some cases, antibiotic prophylaxis may be recommended to prevent infection in individuals who are at high risk of developing Bacteroidaceae infections, such as those with weakened immune systems or chronic medical conditions.

In conclusion, Bacteroidaceae is a family of bacteria that can cause a variety of infections in the body, ranging from mild to severe. Understanding the causes, symptoms, diagnosis, and treatment options for these infections can help healthcare providers provide effective care for individuals who are affected by Bacteroidaceae infections. Preventive measures such as good hygiene practices and antibiotic prophylaxis can also help reduce the risk of developing these infections.

There are several types of periodontal diseases, including:

1. Gingivitis: This is the mildest form of periodontal disease, characterized by redness, swelling, and bleeding of the gums. It is reversible with proper treatment and good oral hygiene.
2. Periodontitis: This is a more severe form of periodontal disease, characterized by the destruction of the periodontal ligament and the jawbone. It can cause teeth to become loose or fall out.
3. Advanced periodontitis: This is the most severe form of periodontal disease, characterized by extensive bone loss and severe gum damage.
4. Periodontal abscess: This is a pocket of pus that forms in the gum tissue as a result of the infection.
5. Peri-implantitis: This is a condition that affects the tissues surrounding dental implants, similar to periodontal disease.

The causes and risk factors for periodontal diseases include:

1. Poor oral hygiene
2. Smoking
3. Diabetes
4. Genetic predisposition
5. Hormonal changes during pregnancy or menopause
6. Poor diet
7. Stress
8. Certain medications

The symptoms of periodontal diseases can include:

1. Redness, swelling, and bleeding of the gums
2. Bad breath
3. Loose teeth or teeth that feel like they are shifting in their sockets
4. Pus between the teeth and gums
5. Changes in the way teeth fit together when biting down

Treatment for periodontal diseases typically involves a combination of professional cleaning, antibiotics, and changes to oral hygiene habits at home. In severe cases, surgery may be necessary to remove infected tissue and restore the health of the teeth and gums.

Preventing periodontal diseases includes:

1. Brushing teeth at least twice a day with a fluoride toothpaste
2. Flossing once a day to remove plaque from between the teeth
3. Using an antibacterial mouthwash
4. Eating a balanced diet and avoiding sugary or acidic foods
5. Quitting smoking
6. Maintaining regular dental check-ups and cleanings.

... runs in the patient's family. Familial aggregation of aggressive periodontitis is often discovered by ... Caries levels have seen to be lower in cases of aggressive periodontitis. Staging Cases of aggressive periodontitis have been ... Localized aggressive periodontitis (LAP) Generalized aggressive periodontitis (GAP) LAP is localised to first molar or incisor ... "Differential Diagnosis between Chronic versus Aggressive Periodontitis and Staging of Aggressive Periodontitis: A Cross- ...
"FAM5C contributes to aggressive periodontitis". PLOS ONE. 5 (4): e10053. Bibcode:2010PLoSO...510053C. doi:10.1371/journal.pone. ... "FAM5C contributes to aggressive periodontitis". PLOS ONE. 5 (4): e10053. Bibcode:2010PLoSO...510053C. doi:10.1371/journal.pone. ...
Another example is that the cause of aggressive periodontitis - resulting in rapid bone loss and teeth in need of extraction - ... "Aggressive periodontitis: The unsolved mystery" (PDF). Quintessence International. doi:10.3290/j.qi.a37387. Varmus, H.; ...
Aggressive periodontitis was found in 5.9% of the subjects (4.3% localized and 1.6% generalized). This was significantly ... Levin L, Baev V, Lev R, Stabholz A, Ashkenazi M (August 2006). "Aggressive periodontitis among young Israeli army personnel". J ... Albandar, JM; Muranga, MB; Rams, TE (2002). "Prevalence of aggressive periodontitis in school attendees in Uganda". Journal of ... Ereş, G; Saribay, A; Akkaya, M (2009). "Periodontal treatment needs and prevalence of localized aggressive periodontitis in a ...
Aggressive Periodontitis (slight: 1-2 mm CAL; moderate: 3-4 mm CAL; severe: > 5 mm CAL) A. Localised B. Generalised (> 30% of ... Aggressive periodontitis involves inflammation of the gingiva and rapid and severe destruction of the periodontal ligament, ... Non-Dental Biofilm-Induced Periodontitis: Necrotizing Periodontal Diseases Periodontitis Periodontitis as a Manifestation of ... "Serum Levels of Cytokines in Subjects With Generalized Chronic and Aggressive Periodontitis Before and After Non-Surgical ...
"Microbiological Characterization in Children with Aggressive Periodontitis". Journal of Dental Research. 91 (10): 927-933. doi: ... There have been, however, a number of recent studies that identified the bacteria in healthy patients without periodontitis and ... "Impact of Periodontal Therapy on the Subgingival Microbiota of Severe Periodontitis: Comparison Between Good Responders and ... have also found that the bacterium is more commonly found in healthier patients when compared to patients with periodontitis. ...
"Infection patterns in chronic and aggressive periodontitis". Journal of Clinical Periodontology. 32 (10): 1055-61. doi:10.1111/ ... Well studied Periodontal pathogens are bacteria that have been shown to significantly contribute to periodontitis. Dental ... of species that have been shown to be more closely related to the initial incidence and continued persistence of periodontitis ...
found in the mouth (e.g. Aggregatibacter actinomycetemcomitans). These are a cause of aggressive juvenile periodontitis. ...
... patients who have heavily broken down teeth or very mobile teeth due to diseases such as generalised aggressive periodontitis. ... "Fixed rehabilitation of patient with aggressive periodontitis using zygoma implants". Indian J Dent Res. 21. Kahnberg, Karl- ...
"Gene expression signatures in chronic and aggressive periodontitis: a pilot study". European Journal of Oral Sciences. 112 (3 ...
... in aggressive periodontitis, previously known as juvenile periodontitis. In 1982, Slots developed tryptic soy-serum-bacitracin- ... It was Slots' work, along with that of Newman, Socransky and others, that substantiated aggressive periodontitis as a bona fide ... Fryman A, Simonian K. Aggressive periodontitis: the historic quest for understanding. CDA Journal 2011;39(6):377-382 (Articles ... The predominant cultivable organisms in juveline periodontitis. Scand J Dent Res 1976;84(1):1-10 van Steenbergen, TJM. " ...
SNPs in aggressive periodontitis patients". Genes and Immunity. 4 (1): 22-9. doi:10.1038/sj.gene.6363900. PMID 12595898. ...
Its role in aggressive periodontitis was first discovered by Danish-born periodontist Jørgen Slots, a professor of dentistry ... A systematic screen by RNA-seq and RT-PCR in HK1651 strain (a clinical isolate from an aggressive periodontitis patient), ... Although it has been found more frequently in localized aggressive periodontitis, prevalence in any population is rather high. ... 1985). The species has attracted attention because of its association with localized aggressive periodontitis. Recent studies ...
"Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes". ... that macrophages derived by culturing the monocytes isolated from the blood of patients with Localized aggressive periodontitis ...
2004). "Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese ...
Nowzari is known for his advocacy against early in life periodontal disease (aggressive periodontitis). In an effort to bring ...
Differential Diagnosis between Chronic versus Aggressive Periodontitis and Staging of Aggressive Periodontitis: A Cross- ... Periodontitis initially begins as gingivitis and can progress onto chronic and subsequent aggressive periodontitis according to ... Chronic periodontitis is one of the seven categories of periodontitis as defined by the American Academy of Periodontology 1999 ... "Patients with periodontitis were more likely to have poorly differentiated oral cavity SCC than those without periodontitis ( ...
In cases of aggressive periodontitis three major species of bacteria have been identified within the periodontal pocket. These ...
... of mRNAs for the various diacylglycerol kinase isoforms in neutrophils from patients with localized aggressive periodontitis". ...
... gene cluster are not associated with aggressive periodontitis in a large Caucasian population". Genomics. 92 (5): 309-15. doi: ...
... administration of doxycycline versus metronidazole plus amoxicillin in the treatment of localized aggressive periodontitis: a ...
Patients often present with early-onset aggressive periodontitis associated with advanced alveolar bone loss and tooth mobility ... Dental practitioners who notice child patients who present with recurrent unexplained gingivitis and periodontitis along with ...
A Gram-negative, facultative anaerobe, nonmotile bacterium often found in association with localized aggressive periodontitis, ... Slots J (January 1976). "The predominant cultivable organisms in juvenile periodontitis". Scandinavian Journal of Dental ... and also suspected to be involved in chronic periodontitis. It was originally described as Bacterium actinomycetemcomitans (30 ...
The role of cathepsin C in Papillon Lefevre syndrome Prepubertal Periodontitis and Aggressive Periodontitis. Human Mutat. 23: ... K.A. Abdel-Ghaffar, N.I. Ragy, and M.O. Wasfy: The Predominant Cultivable Microflora of Early-Onset Periodontitis (EOP) in ... from early-onset periodontitis patients. Ain Shams Dental Journal, volume IV, no. 4, 173-180, Dec. 2001 22. A. El Awady, K.S. ... from early-onset periodontitis (EOP) patients. J Dent Res (abs), March 1994 4. Parlar A, Cafesse R, Rossmann JA, Oygurt, Balos ...
The seven categories are as follows: Gingivitis Chronic periodontitis Aggressive periodontitis Periodontitis as a manifestation ... also increase susceptibility to periodontitis. Periodontitis may be associated with higher stress. Periodontitis occurs more ... Periodontitis Necrotizing periodontal diseases Necrotizing Gingivitis Necrotizing periodontitis Necrotizing stomatitis ... although this may be a symptom of progressing periodontitis in that person. Periodontitis has been linked to increased ...
... discovering the immunogenetic basis of aggressive periodontitis, reporting the viral cause of Kaposi's sarcoma (HHIV-8) in the ...
"Adult periodontitis" was reclassified "chronic periodontitis" and "early-onset periodontitis" to "aggressive periodontitis". ... "chronic periodontitis" and "aggressive periodontitis" Introduction of "Systemic Diseases" and Conditions Affecting the ... Aggressive periodontitis may occur in younger persons and there may a genetic aspect, with the trait sometimes running in ... Aggressive periodontitis is distinguished from the chronic form mainly by the faster rate of progression. Loss of attachment ...
Periodontitis. Animal model: periodontitis in the rice rat (Oryzomys palustris). American Journal of Pathology 96(2):643-646. ... They are aggressive towards conspecifics and emit high-pitched squeaks while fighting. In dense vegetation, their perceptual ... The marsh rice rat is quite susceptible to periodontitis and has been used as a model system for the study of that disease. The ... Rice rats also eat eggs and young of the seaside sparrow (Ammodramus maritimus) and are aggressive towards the sparrow, ...
Periodontitis Perioral dermatitis Peripartum cardiomyopathy Peripheral blood vessel disorder Peripheral nervous disorder ... Parturiphobia Paruresis Parvovirus antenatal infection Pascuel-Castroviejo syndrome Pashayan syndrome Passive-aggressive ...
When P. nigrescens microflora colonize they trigger an over-aggressive response from the immune system and increase the ... "Association of periodontitis with increased colonization by Prevotella nigrescens". Journal of Investigative and Clinical ... and Porphyromonas gingivalis are associated with signs of carotid atherosclerosis in subjects with and without periodontitis". ...
Melanoma is a malignant proliferation of melanocytes and the most aggressive type of skin cancer. Acral lentiginous melanoma ... palmoplantar keratoderma with periodontitis and arachnodactyly and acro-osteolysis) Hidrotic ectodermal dysplasia (alopecia ... Aggressive digital papillary adenocarcinoma (digital papillary adenocarcinoma, papillary adenoma) Apocrine gland carcinoma ... palmoplantar keratoderma with periodontitis) Porokeratosis plantaris discreta Punctate palmoplantar keratoderma Schöpf-Schulz- ...
The view that occlusal trauma (as may occur during bruxism) is a causative factor in gingivitis and periodontitis is not widely ... Personality traits are also commonly discussed in publications concerning the causes of bruxism, e.g. aggressive, competitive ...
Setting on a path of aggressive acquisitions, Pearson ultimately turned Valeant into a platform company that grows by ... an antibiotic used for procedures related to periodontitis Efinaconazole (Jublia), for treatment of toenail fungus Acne drugs: ... Valeant said that it would cut ties with Philidor in response to allegations of aggressive billing practices. Walgreens Boots ...
While some cases of gingivitis never progress to periodontitis, periodontitis is always preceded by gingivitis. Gingivitis is ... age osteoporosis low dental care utilization poor oral hygiene overly aggressive oral hygiene such as brushing with stiff ... Periodontitis can ultimately lead to tooth loss. The symptoms of gingivitis are somewhat non-specific and manifest in the gum ... Recurrence of gingivitis Periodontitis Infection or abscess of the gingiva or the jaw bones Trench mouth (bacterial infection ...
... aggressive, teratoma-initiating embryonic-like carcinoma cells during differentiation. The survival of these teratoma- ... regeneration and are a promising source of readily accessible stem cells for use in the clinical treatment of periodontitis. ...
Tetracycline has been used with some success in the treatment of localised juvenile periodontitis and this has proven to be ... Some dental treatments may cause bacteraemia, such as tooth extractions, subgingival scaling or even simple aggressive tooth ... Studies conducted to investigate the effects of antibiotics on patients with acute periapical periodontitis and acute apical ... "Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults" (PDF). Cochrane Database of ...
Perri R, Nares S, Zhang S, Barros SP, Offenbacher S (January 2012). "MicroRNA modulation in obesity and periodontitis". Journal ... "Regulation of cancer aggressive features in melanoma cells by microRNAs". PLOS ONE. 6 (4): e18936. doi:10.1371/journal.pone. ...
The hallmark feature of periodontitis is attachment loss of the tooth from the alveolar bone. Periodontitis is an irreversible ... It is usually invaded by surrounding bone tissue and aggressive surgical removal is required. Also known as feline cervical ... it is also called periodontal disease or periodontitis. It begins with the formation of plaque, specifically subgingival plaque ...
Another consistent observation in itgb6-/- mice is periodontitis. αvβ6 is expressed in the junctional epithelium of the gums, ... activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive ...
Periodontitis and tooth loss are common in people with rheumatoid arthritis. RA is a systemic (whole body) autoimmune disease. ... The aggressive phenotype of fibroblast-like synoviocytes in rheumatoid arthritis and the effect these cells have on the ... Two bacterial species associated with periodontitis are implicated as mediators of protein citrullination in the gums of people ... de Pablo P, Chapple IL, Buckley CD, Dietrich T (April 2009). "Periodontitis in systemic rheumatic diseases". Nature Reviews. ...
MUNOZ, Miguel Angel et al. Genetic and immunological features of aggressive periodontitis. RSBO (Online) []. 2010, 7, 1, pp. 90 ... INTRODUCTION AND OBJECTIVE: Aggressive periodontitis intrigues clinicians and researchers due to its rapid progression and its ... CONCLUSIONS: In the presence of dental biofilm, host susceptibility to aggressive periodontitis varies among regions, countries ... Immune-inflammatory processes that seem to be modified in aggressive periodontitis patients may be transmitted vertically, ...
Impact of aggressive periodontitis and chronic periodontitis on oral health-related quality of life.. Llanos, Alexandre Hugo; ... or Chronic Periodontitis (CP) were included nine patients with Localized Aggressive Periodontitis (LAP), thirty-three patients ... with Generalized Aggressive Periodontitis (GAP) and ten patients with Generalized Chronic Periodontitis (GCP). Oral Health ... Fifty-two patients with Aggressive Periodontitis (AP) ... in the patients with the generalized forms of periodontitis. ...
Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.Jun 23, 2022 ... Diseases : Advanced Glycation End products (AGE), Endotoxemia, Periodontitis. Pharmacological Actions : Anti-Inflammatory ...
Eosinophilic granuloma may masquerade as an aggressive periodontitis [14] ; therefore, EG should be considered when an ... Eosinophilic granuloma masquerading as aggressive periodontitis. J Periodontol. 2006 May. 77(5):917-21. [QxMD MEDLINE Link]. ... The presentation of EG may be solitary, which rarely requires treatment, or multisystem, which requires aggressive therapy. [8 ...
9. Aggressive periodontitis with supernumerary teeth: a retrospective study.. Açikgöz G; Açikgöz A; Keskiner I; Türk T; Otan F ... 2. Aggressive periodontitis associated with Fanconis anemia. A case report.. Nowzari H; Jorgensen MG; Ta TT; Contreras A; ...
in his study of 93 patients with generalized aggressive periodontitis and 91 healthy controls showed that sera from patients ... C-reactive protein levels in patients with aggressive periodontitis. Journal of periodontology, 2006, 77(6):933-9. ... Periodontitis is a chronic inflammatory reaction to a specific group of bacteria that results in destruction of the supporting ... Lab-on-a-chip methods for point-of-care measurements of salivary biomarkers of periodontitis. Annals of the New York Academy of ...
New Clinical Study Demonstrates ARESTIN Decreases Certain Periodontitis Pathogens. Neanderthal Tartar Helps Unlock New Field of ... The study looks at a sample of New York dentists who completed a survey asking about 21 specific types of aggressive behaviors ... Experience with an aggressive patient is nothing new for most dentists .social-ris-container { display: flex; justify-content: ... and de-escalating when a patient does become aggressive. ...
... casein and whey protein intakes and periodontitis among Danish adults - Volume 19 Issue 3 ... Genetic and environmental risk factors for chronic periodontitis and aggressive periodontitis. Periodontol 2000 53, 138-153. ... Descriptive data according to periodontitis status are presented in Table 1. Individuals presenting severe periodontitis were ... and severe periodontitis. In the crude models none of the nutrients was significantly associated with periodontitis, except ...
Aggregatibacter is associated with aggressive periodontitis.[7]. Organisms involved in periodontal disease organize into ... Aggregatibacter actinomycetemcomitans and its relationship to initiation of localized aggressive periodontitis: longitudinal ...
In particular, the incidence of aggressive and difficult to treat forms of periodontitis is well-documented in patients with DM ... Periodontitis is now recognized as one of the six major complications of diabetes. It appears that although all diabetics may ... A detailed epidemiological analysis of periodontitis and tooth loss in the Pima Indians showed that the incidence of diabetes- ... o Clarification of the microbiological and biochemical role of calculus in the onset of periodontitis in diabetic subjects. o ...
Phenotypic and functional analysis of peripheral blood mononuclear cells in generalised aggressive and chronic periodontitis ...
Early-Onset Periodontitis Juvenile Periodontitis Periodontitis, Aggressive, 1 Periodontitis, Circumpubertal Periodontitis, ... Periodontitis, Aggressive, 1 Narrower Concept UI. M000649146. Terms. Periodontitis, Aggressive, 1 Preferred Term Term UI ... A localized aggressive periodontitis, formerly called localized juvenile periodontitis. It is a destructive form of ... Aggressive Periodontitis Preferred Term Term UI T706688. Date09/27/2007. LexicalTag NON. ThesaurusID NLM (2009). ...
This patient was diagnosed with aggressive periodontitis and presented with a mandibular right canine with advanced periodontal ... This patient presented with generalized advanced chronic periodontitis (AAP type IV) and had been previously told that her ... online oral cancer Oral health Oral healthcare oral hygiene orthodontics pandemic patients periodontal disease periodontitis ...
A December study in Lancet Diabetes Endocrinology( found that aggressive periodontitis treatment could ...
... is the etiologic agent of localized aggressive periodontitis (LAP) and other systemic infections, including infective ...
Association of MMP-2 -753C,T and MMP-9 -1562C,T Polymorphisms with Chronic/Aggressive Periodontitis Risk: A Systematic Review ...
... microorganisms and distribution of Porphyromonas gingivalis fimA genotypes in Chinese patients with aggressive periodontitis. ... Relationship between herpesviruses and adult periodontitis and periodontopathic bacteria. Contreras A, Umeda M, Chen C, Bakker ...
Orthodontic treatment of an adult patient with aggressive periodontitis A case report. IIUM Journal of Orofacial and Health ...
Actinobacillus actinomycetemcomitans, the predominant pathogen in aggressive periodontitis was reported to be able to produce a ... these periodontitis associated species are integrated into microbial communities. For example, Filifactor alocis, an emerging ... dental caries and periodontitis (Marsh, 1994). The environmental diversity of the oral cavity promotes the establishment of ... As for Tannerella forsythia which is associated with severe and chronic periodontitis, its cell surface glycoproteins in S- ...
Aggressive periodontitis can lead to tooth loss if left untreated. Necrotizing Periodontitis It is the most severe form of ... Aggressive Periodontitis It is a rare form of periodontal disease that progresses quickly. It happens in deep pockets of plaque ... Periodontitis It is a more advanced form of periodontal disease. It occurs as deeper pockets of plaque and tartar between the ... Periodontitis can be mild to severe, depending on the degree of the bone and gum damage. In extreme circumstances, the teeth ...
Generalized Aggressive Periodontitis is 3X more likely if too much Vitamin D-Binding Protein - Nov 2016 09 Nov, 2017 ... Periodontitis reduced by Vitamin D - many studies 05 Jun, 2023 Chronic periodontitis associated with low vitamin D and low ... Severe periodontitis is half as likely at 60 ng of vitamin D - Sept 2021 1043 visitors, last modified 26 Nov, 2021, Copy URL. ... exhibited severe periodontitis. Serum 25(OH)D showed a significantly negative association with severe periodontitis after ...
Photodynamic therapy in aggressive periodontitis. Prof. Dr. T. Auschill, Prof. Dr. N. Arweiler, Dr. M. Pietruska, Dr. J. ... Antimicrobial photodynamic therapy as adjunct to the non-surgical treatment of Aggressive Periodontitis without the use of ... The comparison of photodynamic and antibiotic therapy in patients with aggressive periodontitis: Preliminary results. Prof. Dr ... Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: microbiological profile. Prof. Dr ...
Periodontitis, Aggressive Periodontitis, Circumpubertal Periodontitis, Early-Onset Periodontitis, Juvenile Periodontitis, ... Periodontitis, Aggressive, 1. Periodontitis, Circumpubertal. Periodontitis, Early-Onset. Periodontitis, Juvenile. Periodontitis ... Aggressive Periodontitis Entry term(s). Circumpubertal Periodontitis Early Onset Periodontitis Early-Onset Periodontitides ... A localized aggressive periodontitis, formerly called localized juvenile periodontitis. It is a destructive form of ...
Aggressive brushing. Brushing your teeth too hard for a prolonged period of time can cause the enamel on your teeth to wear ... If you have a condition, such as periodontitis, it can cause destructive gum inflammation and lead to gum recession. You can ...
Early-Onset Periodontitis Juvenile Periodontitis Periodontitis, Aggressive, 1 Periodontitis, Circumpubertal Periodontitis, ... Periodontitis, Aggressive, 1 Narrower Concept UI. M000649146. Terms. Periodontitis, Aggressive, 1 Preferred Term Term UI ... A localized aggressive periodontitis, formerly called localized juvenile periodontitis. It is a destructive form of ... Aggressive Periodontitis Preferred Term Term UI T706688. Date09/27/2007. LexicalTag NON. ThesaurusID NLM (2009). ...
... , Health Newstrack ... Shared genetic link between dental disease periodontitis and heart attack , Health Newstrack , ... in a group of 151 patients suffering from the most aggressive, early-onset forms of periodontitis, and a group of 1097 CHD ... Shared genetic link between dental disease periodontitis and heart attack. 30 May 19 Thu. 26 May 09 Tue. by Editor Health News ...
Aggressive periodontitis occurs in patients who are otherwise clinically healthy. Common features include rapid attachment loss ... Genetics may play role - Some patients may be predisposed to a more aggressive type of periodontitis. Patients with a family ... Periodontitis. Untreated gingivitis can advance to periodontitis. With time, plaque can spread and grow below the gum line. ... Periodontitis as a manifestation of systemic diseases often begins at a young age. Systemic conditions such as heart disease, ...
  • In particular, the incidence of aggressive and difficult to treat forms of periodontitis is well-documented in patients with DM. (
  • Classification Forms of Periodontitis AAP World Workshop in Clinical Periodontics, 1989 Adult periodontitis Early-onset periodontitis (may be prepubertal, juvenile, or rapidly progressive) Periodontitis associated with systemic disease 1 This system of classification is used as a means to properly diagnose and treat individuals with periodontal problems. (
  • The overall classification system aimed to differentiate the more common forms of periodontitis, i.e. 11 595 The Periodontal Disease Classification System of the AAP - An Update pemphigoid), allergic reactions (e.g., restorative materials, toothpastes, gum Secondly, a new identification and classification system of periodontitis has been defined. (
  • We studied a genetic locus on chromosome 9p21.3 that had previously been identified to be associated with myocardial infarction, in a group of 151 patients suffering from the most aggressive, early-onset forms of periodontitis, and a group of 1097 CHD patients who had already had a heart attack. (
  • There are many forms of periodontitis. (
  • According to the 1999 classification, chronic and aggressive periodontitis were considered to represent different disease entities. (
  • Serum nitric oxide concentration in generalized chronic and aggressive periodontitis in the Mexican population is not related to the severity of the disease. (
  • Journal of the Canadian Dental Association December 2000, Vol. Classification included only gingivitis and periodontitis. (
  • Periodontal (gum) diseases, including gingivitis and periodontitis, are serious infections that, left untreated, can lead to tooth loss. (
  • Oral rehabilitation was undertaken in 15 patients treated for generalized aggressive periodontitis (GAgP), 12 patients treated for generalized chronic periodontitis (GCP), and 12 periodontally healthy patients. (
  • Immune-inflammatory processes that seem to be modified in aggressive periodontitis patients may be transmitted vertically, explaining familial aggregation associated with this disease. (
  • Expression of growth mediators in the gingival crevicular fluid of patients with aggressive periodontitis undergoing periodontal surgery. (
  • To describe changes in growth factor mediators in the gingival crevicular fluid (GCF) of patients with aggressive periodontitis (AgP) undergoing regenerative (GTR) and access flap (AF) surgery . (
  • Assessment and Comparison of Ghrelin and Chemerin Levels in Gingival Crevicular Fluid and Serum as Predictive Biomarkers in Aggressive Periodontitis Patients: A Study Protocol', European Journal of Molecular & Clinical Medicine , 7(2), pp. 2027-2033. (
  • Researchers believe a larger, nationwide study is merited, and also advise dental professionals to seek education about preventing aggression from patients, and de-escalating when a patient does become aggressive. (
  • Do patients with aggressive periodontitis have evidence of diabetes? (
  • The scientists went on to verify the association in further groups of 1100 CHD patients and 180 periodontitis patients. (
  • Now we know for sure that there is a strong genetic link, patients with periodontitis should try to reduce their risk factors and take preventive measures at an early stage", he said. (
  • Genetics may play role - Some patients may be predisposed to a more aggressive type of periodontitis. (
  • Periodontitis can lead to bone loss and tooth loss if left untreated. (
  • We intend to push ahead with our work to try to understand more about the function of this RNA molecule and the pathway in which it operates in healthy gums and also in periodontitis. (
  • Abstract: The Gram negative pathogen, Aggregatibacter actinomycetemcomitans, is the etiologic agent of localized aggressive periodontitis (LAP) and other systemic infections, including infective endocarditis. (
  • Our aim was to study the relationship between gum infections such as periodontitis as a risk factor for cerebral ischemic stroke and its correlation of periodontitis staging for stroke. (
  • Periodontitis was reclassified as chronic, aggressive (localized and generalized), necrotizing and as a manifestation of systemic disease. (
  • 3. Classification of these conditions should be based on the primary systemic disease Classification of Diseases and Related Periodontitis Fine et al. (
  • Severe periodontitis was defined as having ≥2 inter-proximal sites with clinical attachment loss ≥6 mm (not on the same tooth) and ≥1 inter-proximal site with pocket depth ≥5 mm. (
  • Intake of vitamin D alone was not associated severe with periodontitis. (
  • However, studies on the relationship between severe periodontitis and serum 25-hydroxyvitamin D 25(OH)D are limited. (
  • This study is designed to explore the relationship between 25(OH)D and severe periodontitis. (
  • Severe periodontitis and serum 25(OH)D were the dependent and independent variables, respectively. (
  • Univariate, multivariate, and subgroup analyses were performed to explore the relationship between severe periodontitis and serum 25(OH)D. (
  • Among the 2928 participants, the average age of the population was 50 ± 13.71 years old, with 1425 (48.67%) males, 316 (10.79%) exhibited severe periodontitis. (
  • Serum 25(OH)D showed a significantly negative association with severe periodontitis after adjusting all variables (OR 0.75, 95% CI 0.63-0.89). (
  • In addition, severe periodontitis has a nonlinear relationship with serum 25(OH)D, whoes inflection point was 102 (nmol/L). On the left side of the inflection point (25(OH)D ≤ 102 nmol/L), the effect size was 0.98 and 95%CI was 0.98-0.99 (25(OH)D per 1 nmol/L increments). (
  • Papillon lefevre syndrome (PLS) belongs to a heterogeneous group of skin diseases that are characterized by hyperkeratosis of palms and soles and presence of severe and early onset periodontitis. (
  • Aggressive periodontitis intrigues clinicians and researchers due to its rapid progression and its evidences of genetic character. (
  • The purpose of this study was to review the literature in order to comprehend the genetic and immunological features of aggressive periodontitis. (
  • Comparative evaluation of GCF & Serum "levels of Ghrelin and Chemerin" as the (Predictive) biomarkers of inflammation in aggressive periodontitis. (
  • If you have a condition, such as periodontitis, it can cause destructive gum inflammation and lead to gum recession. (
  • This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people. (
  • Replacement of "Early-Onset Periodontitis" with "Aggressive Periodontitis" (Table 2, Section III) There are forms of periodontal disease that clearly differ from chronic periodontitis. (
  • A NEW CLASSIFICATION OF PERIODONTITIS The 1989 workshop recognized that periodontitis had several distinct clinical presentations, different ages of onset and rates of progression. (
  • The 1999 classification, criticizing the concept and definition of an early onset periodontitis, has replaced it with aggressive periodontitis, has recognized the gingival diseases as a precursor of periodontitis (even though the). (
  • Group I includes 40 GCF samples from 40 subjects with aggressive and Group II includes 40 Serum samples from 40 subjects with aggressive periodontitis group. (
  • Coronary heart disease is the leading cause of death worldwide, and periodontitis, which leads to the loss of connective tissue and the bone support of teeth, is the major cause of tooth loss in adults over 40 years. (
  • It is a destructive form of periodontitis characterized by ALVEOLAR BONE LOSS of the MOLARS and INCISORS . (
  • Surveys of aggressive periodontitis that use only clinical examinations, without radiographic examination to confirm the presence of a distinctive pattern of tissue loss, may overestimate the prevalence of this disease, particularly when a low threshold of attachment loss is used. (
  • Extensive clinical studies have indicated that the oral microbial flora is responsible for two major human diseases: dental caries and periodontitis ( Marsh, 1994 ). (
  • Effect of surgical periodontal treatment associated to antimicrobial photodynamic therapy on chronic periodontitis: A randomized controlled clinical trial. (
  • In the presence of dental biofilm, host susceptibility to aggressive periodontitis varies among regions, countries and races. (
  • The prevalence of aggressive periodontitis varies significantly between populations, and differences in race/ethnicities seem to be a key factor. (
  • Inflamación y pérdida del PERIODONTIO que se caracteriza por rápidas destrucción ósea y pérdida del sistema de unión en presencia de factores locales como la PLACA DENTAL y CÁLCULO DENTAL. (
  • The relationship between the dental disease periodontitis and coronary heart disease (CHD) has been known for several years. (
  • Epidemiologic studies of aggressive periodontitis have used different study designs and a range of examination methods and case definitions, and this greatly complicates the study of disease prevalence in populations. (
  • Studies consistently show that aggressive periodontitis is most prevalent in Africa and in populations of African descent and is least prevalent in Caucasians in Europe and North America. (
  • These findings show that aggressive periodontitis is a significant health problem in certain populations. (
  • Epidemiologic studies of aggressive periodontitis in high-risk populations are important and could provide vital data on the determinants of this disease, and this information is needed for the establishment of effective health-promotion measures. (
  • Review Article A New Classification of Endodontic-Periodontal Lesions KhalidS.Al-Fouzan College of Dentistry, King Saud Bin Abdulaziz University, King Abdulaziz Medical City No. Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions, S162-S170. (
  • A localized aggressive periodontitis, formerly called localized juvenile periodontitis. (
  • Periodontitis is now recognized as one of the six major complications of diabetes. (
  • 9. Aggressive periodontitis with supernumerary teeth: a retrospective study. (
  • Periodontitis can lead to the destruction of periodontium and adversely influence the overall health, wellbeing, and quality of life. (
  • To investigate whether intakes of Ca, vitamin D, casein and whey are associated with periodontitis and to investigate the possibility of interactions between them. (
  • The presentation of EG may be solitary, which rarely requires treatment, or multisystem, which requires aggressive therapy. (
  • Periodontitis is very common, and around 90% of people aged over 60 suffer from it. (
  • classification of periodontitis 6,7,8 which has been in use for the last 19 years. (
  • Over much of the last century clinicians and researchers have grappled with the … 66, No. Abstract Objective Since the initial description of aggressive periodontitis (AgP) in the early 1900s, classification of this disease has been in flux. (
  • In the meantime, because of its association with CHD, we think that periodontitis should be taken very seriously by dentists and diagnosed and treated as early as possible", said Dr. Schaefer. (
  • An unusual variation of the condition known as necrotizing periodontitis frequently affects persons with compromised immune systems. (
  • Periodontitis is an independent risk factor for cerebral ischemia and is a treatable and preventable disease. (