A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.
A family of coccoid to rod-shaped nonsporeforming, gram-negative, nonmotile, facultatively anaerobic bacteria that includes the genera ACTINOBACILLUS; HAEMOPHILUS; MANNHEIMIA; and PASTEURELLA.
Infections with bacteria of the family PASTEURELLACEAE.
Infections with bacteria of the genus ACTINOBACILLUS.
Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
A species of Gram-negative, facultatively anaerobic pleomorphic rod-shaped often filamentous bacteria in the genus of AGGREGATIBACTER found in the oral cavity. It is associated with DENTAL PLAQUE; and BACTERIAL ENDOCARDITIS.
A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to oral cavity and pharynx. It is associated with BACTERIAL ENDOCARDITIS; and MENINGITIS.
Toxins produced, especially by bacterial or fungal cells, and released into the culture medium or environment.
A genus of PASTEURELLACEAE. Members are nonmotile, Gram-negative, facultatively anaerobic rods or coccobacilli. Its members are X factor (HEMIN) independent and variably dependent on V factor (NAD).
Oral tissue surrounding and attached to TEETH.
Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.
A species of CAMPYLOBACTER isolated from cases of human PERIODONTITIS. It is a microaerophile, capable of respiring with OXYGEN.
An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.
Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY.
A species of bacteria in the family SPIROCHAETACEAE, frequently isolated from periodontal pockets (PERIODONTAL POCKET).
Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium is a common commensal in the gingival crevice and is often isolated from cases of gingivitis and other purulent lesions related to the mouth.
A species of gram-negative, anaerobic, rod-shaped bacteria isolated from the gingival margin and sulcus and from infections of the upper respiratory tract and pleural cavity.
A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.
Devices used in the home by persons to maintain dental and periodontal health. The devices include toothbrushes, dental flosses, water irrigators, gingival stimulators, etc.
A genus of PASTEURELLACEAE described as gram-negative, nonsporeforming, nonmotile, facultative anaerobes. Most members are found both as pathogens and commensal organisms in the respiratory, alimentary, and genital tracts of animals.
Measurable quantity of bacteria in an object, organism, or organism compartment.
A genus of gram-negative, facultatively anaerobic bacteria in the family CARDIOBACTERIACEAE. It is found in the nasal flora of humans and causes ENDOCARDITIS.
Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.
An inflammatory process with loss of supporting bone in the tissues surrounding functioning DENTAL IMPLANTS.
The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.
Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.
Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
A species of gram-positive, facultatively anaerobic bacteria in the family STREPTOCOCCACEAE. It is a normal inhabitant of the human oral cavity, and causes DENTAL PLAQUE and ENDOCARDITIS. It is being investigated as a vehicle for vaccine delivery.
An index which scores the degree of dental plaque accumulation.
A species of gram-negative bacteria (currently incertae sedis) causing multisystem disease in CATTLE.
A numerical rating scale for classifying the periodontal status of a person or population with a single figure which takes into consideration prevalence as well as severity of the condition. It is based upon probe measurement of periodontal pockets and on gingival tissue status.
Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.
Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.
A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.
Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.
A fluid occurring in minute amounts in the gingival crevice, believed by some authorities to be an inflammatory exudate and by others to cleanse material from the crevice, containing sticky plasma proteins which improve adhesions of the epithelial attachment, have antimicrobial properties, and exert antibody activity. (From Jablonski, Illustrated Dictionary of Dentistry, 1982)
The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.
Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.
Proteins found in any species of bacterium.
Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).
A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
The genetic complement of a BACTERIA as represented in its DNA.
Substances that reduce the growth or reproduction of BACTERIA.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

Phenotypic variation in Actinobacillus actinomycetemcomitans during laboratory growth: implications for virulence. (1/6)

This study examined alteration of specific virulence traits associated with phenotypic changes seen when a low-passage disease-associated and well maintained parent strain of Actinobacillus actinomycetemcomitans was compared to a laboratory-grown spontaneous variant/mutant. Clinical isolates of A. actinomycetemcomitans recovered from periodontitis patients typically grow as rough, adherent colonies on primary culture but undergo transformation to smooth, non-adherent colonies following repeated passage in vitro. The relationship of these phenotypic changes to the virulence of the organism or to the processes that underlie this transformation are not understood. A fresh clinical isolate, designated strain CU1000, was obtained from the first molar site of a patient with classical signs of localized juvenile periodontitis and used as the parent strain to study virulence-related phenotypes. Following several passages of CU1000 on selective agar, a spontaneous variant that demonstrated smooth, opaque, non-adherent colonies was isolated and designated strain CU1060. This study compared the properties of these two strains with respect to colony morphology, autoaggregation, surface appendages, adherence to saliva-coated hydroxyapatite (SHA), LPS chemotype and activity, induction of fibroblast proteinase activity and antigenic properties. CU1000 demonstrated rough, raised, star-positive colonies which upon electron microscopic examination revealed the presence of large, flexible, bundled fibrils. In addition, CU1000 showed adherence to SHA, several unique protein antigens and elevated endotoxin and fibroblast proteinase activity. CU1060, on the other hand, showed minimal adherence to SHA and fewer reactive proteins compared to the fresh clinical isolates. This strain formed smooth, opaque colonies on agar, showed minimal fibril formation and limited endotoxin and fibroblast-proteinase-inducing activity. These findings demonstrate that clinical isolates of A. actinomycetemcomitans undergo significant virulence-reducing phenotypic alterations during in vitro passage and support the need to study this organism in its clinical form.  (+info)

Structural and genetic analyses of O polysaccharide from Actinobacillus actinomycetemcomitans serotype f. (2/6)

The oral bacterium Actinobacillus actinomycetemcomitans is implicated as a causative agent of localized juvenile periodontitis (LJP). A. actinomycetemcomitans is classified into five serotypes (a to e) corresponding to five structurally and antigenically distinct O polysaccharide (O-PS) components of their respective lipopolysaccharide molecules. Serotype b has been reported to be the dominant serotype isolated from LJP patients. We determined the lipopolysaccharide O-PS structure from A. actinomycetemcomitans CU1000, a strain isolated from a 13-year-old African-American female with LJP which had previously been classified as serotype b. The O-PS of strain CU1000 consisted of a trisaccharide repeating unit composed of L-rhamnose and 2-acetamido-2-deoxy-D-galactose (molar ratio, 2:1) with the structure -->2)-alpha-L-Rhap-(1-3)-2-O-(beta-D-GalpNAc)-alpha-L-Rhap-(1-->* O-PS from strain CU1000 was structurally and antigenically distinct from the O-PS molecules of the five known A. actinomycetemcomitans serotypes. Strain CU1000 was mutagenized with transposon IS903phikan, and three mutants that were deficient in O-PS synthesis were isolated. All three transposon insertions mapped to a single 1-kb region on the chromosome. The DNA sequence of a 13.1-kb region surrounding these transposon insertions contained a cluster of 14 open reading frames that was homologous to gene clusters responsible for the synthesis of A. actinomycetemcomitans serotype b, c, and e O-PS antigens. The CU1000 gene cluster contained two genes that were not present in serotype-specific O-PS antigen clusters of the other five known A. actinomycetemcomitans serotypes. These data indicate that strain CU1000 should be assigned to a new A. actinomycetemcomitans serotype, designated serotype f. A PCR assay using serotype-specific PCR primers showed that 3 out of 20 LJP patients surveyed (15%) harbored A. actinomycetemcomitans strains carrying the serotype f gene cluster. The finding of an A. actinomycetemcomitans serotype showing serological cross-reactivity with anti-serotype b-specific antiserum suggests that a reevaluation of strains previously classified as serotype b may be warranted.  (+info)

Tight-adherence genes of Actinobacillus actinomycetemcomitans are required for virulence in a rat model. (3/6)

Actinobacillus actinomycetemcomitans is a Gram-negative coccobacillus that has been associated with localized aggressive periodontitis and infections of the heart, brain, and urinary tract. Wild-type clinical isolates have the remarkable ability to adhere tenaciously and nonspecifically to solid surfaces such as glass, plastic, and hydroxyapatite. Adherence by A. actinomycetemcomitans is mediated by the tight-adherence (tad) gene locus, which consists of 14 genes (flp-1-flp-2-tadV-rcpCAB-tadZABCDEFG). All but 2 of the genes have been shown to be required for the secretion and assembly of long, bundled Flp1 fibrils. To test whether the tad locus is required for colonization and disease, we developed a rat model for periodontal disease. To mimic the natural route of infection, Sprague-Dawley rats were inoculated orally by adding bacteria directly to their food for 8 days. After inoculation with wild-type or mutant strains defective in adherence (flp-1 and tadA), the rats were assessed for colonization of the oral cavity and pathogenesis. Wild-type A. actinomycetemcomitans was able to colonize and persist for at least 12 weeks in the oral cavity, elicit a humoral immune response, and cause significant bone loss in rats. In contrast, rats fed flp-1 or tadA mutant strains showed no bone loss and their immune responses were indistinguishable from those of the uninoculated controls. These results demonstrate the critical importance of the tad locus in the colonization and pathogenesis of A. actinomycetemcomitans.  (+info)

Novel surface structures are associated with the adhesion of Actinobacillus actinomycetemcomitans to collagen. (4/6)

Actinobacillus actinomycetemcomitans is a gram-negative, facultative, anaerobic bacterium that colonizes the human oral cavity and the upper respiratory tract. This bacterium is strongly associated with localized aggressive periodontitis and adult periodontitis and is the causative agent for other serious systemic infections. Recently, we have identified a protein, EmaA (extracellular matrix protein adhesin A), that mediates the adhesion of A. actinomycetemcomitans to collagen. The conserved sequence and predicted secondary structure suggest that EmaA is an orthologue of the Yersinia enterocolitica adhesin YadA. Electron microscopy examinations of A. actinomycetemcomitans have identified antenna-like protrusions associated with the surface of the bacterium. These structures are absent on emaA mutant strains and can be restored by transformation of the mutant strain with emaA in trans. The loss of these structures is associated with a decrease in the binding of this bacterium to collagen. The antenna-like structures are composed of a long rod that terminates in an ellipsoidal head region. The analysis of these structures using image processing techniques has provided an initial estimate of the overall dimensions, which suggests that the appendages are oligomeric structures formed by either three or four subunits. Together, the data suggest that emaA is required for the expression of novel appendages on the surface of A. actinomycetemcomitans that mediate the adhesion of the bacterium to collagen.  (+info)

HACEK infective endocarditis: characteristics and outcomes from a large, multi-national cohort. (5/6)

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Epithelial cell invasion by Actinobacillus actinomycetemcomitans strains from restriction fragment-length polymorphism groups associated with juvenile periodontitis or carrier status. (6/6)

The epithelial cell invasiveness of Actinobacillus actinomycetemcomitans strains of different restriction fragment-length polymorphism (RFLP) groups associated with disease conversion and asymptomatic carrier status in localized juvenile periodontitis was examined. Twenty clinical isolates were studied for their ability to invade KB monolayers, using the quantitative gentamicin killing assay. Five isolates were found to be invasive, five were not invasive; and the other 10 did not invade better than an invasion negative control Haemophilus aphrophilus strain ATCC 19415. Using probe-specific DNA fingerprinting. 11 strains were assigned to RFLP group II (disease-associated); 4 to RFLP type XIII (carrier status associated); and the other to groups III, IV, V and VII. Eight isolates, all RFLP group II, were leukotoxin producers as determined by PCR amplification of the lkt promoter region. No correlation was found between invasiveness and RFLP group. Leukotoxin production was more associated with noninvasive than invasive strains.  (+info)

TY - JOUR. T1 - Caesarean section and risk of autism across gestational age. T2 - a multi-national cohort study of 5 million births. AU - Yip, Benjamin Hon Kei. AU - Leonard, Helen. AU - Stock, Sarah. AU - Stoltenberg, Camilla. AU - Francis, Richard W.. AU - Gissler, Mika. AU - Gross, Raz. AU - Schendel, Diana. AU - Sandin, Sven. PY - 2017/4. Y1 - 2017/4. N2 - Background: The positive association between caesarean section (CS) and autism spectrum disorder (ASD) may be attributed to preterm delivery. However, due to lack of statistical power, no previous study thoroughly examined this association across gestational age. Moreover, most studies did not differentiate between emergency and planned CS.Methods: Using population-based registries of four Nordic countries and Western Australia, our study population included 4 987 390 singletons surviving their first year of life, which included 671 646 CS deliveries and 31 073 ASD children. We used logistic regression to estimate odds ratios (OR) and ...
BACKGROUND: Socio-economic inequalities in mortality are observed at the country level in both North America and Europe. The purpose of this work is to investigate the contribution of specific risk factors to social inequalities in cause-specific mortality using a large multi-country cohort of Europeans. METHODS: A total of 3,456,689 person/years follow-up of the European Prospective Investigation into Cancer and Nutrition (EPIC) was analysed. Educational level of subjects coming from 9 European countries was recorded as proxy for socio-economic status (SES). Cox proportional hazard models with a step-wise inclusion of explanatory variables were used to explore the association between SES and mortality; a Relative Index of Inequality (RII) was calculated as measure of relative inequality. RESULTS: Total mortality among men with the highest education level is reduced by 43% compared to men with the lowest (HR 0.57, 95% C.I. 0.52-0.61); among women by 29% (HR 0.71, 95% C.I. 0.64-0.78). The risk ...
After immunoflurescent microscopy DNA mutational analysis is the final step in elucidating the underlying molecular defect, and in most cases, it reduces the number of genes to be screened. DNA is extracted from blood of the patient and family members. Initial mutation screening is performed by restriction fragment-length polymorphism analysis, hotspot analysis, and finally, direct DNA sequencing ...
Whats healthier, a diet high in fat or high in carbohydrates? How can the HEART score be used to stratify patients who present to the Emergency Department with chest pain? Kieran Quinn and Ashley Minuk cover the answers from the findings of two exciting new articles.. With the growing burden of cardiovascular and diet related disease there is a widespread effort to update dietary guidelines. Ashley covers a prospective multi-national cohort study which adds evidence to the impact of various macronutrients - carbohydrates, proteins, fats - on mortality and cardiovascular events.. Next, Kieran guides listeners through the results of a trial of the HEART score, an easy-to-apply instrument to stratify patients with chest pain according to their short term risk for major adverse cardiac events.. Finally, the Good Stuff segment. Gene therapy is here! Kieran covers a new FDA approved treatment for leukemia. Ashley covers the exercise paradox: physical activity may do less than one would hope to ...
This study was an extension to study MA21573 [NCT00750880], which was an open label single arm study to investigate the safety, tolerability and efficacy of
This trial investigated the tolerability, efficacy and pharmacokinetics of beclometasone/fomoterol [CHF1535, Foster; Chiesi Farmaceutici], alone or in
In 2013, the Organisation for Economic Cooperation and Development (OECD) announced its Action Plan on Base Erosion and Profit Shifting…
MTI wanted to refresh its communications infrastructure to encourage mobile working and a paperless environment. To do so, it needed to find a way to improve call extension efficiency using smartphones.
Red Hat, Inc. (Nasdaq:RHAT), the worlds premier open source and Linux provider, today announced the appointment of Charles E. Peters, Jr. as Executive Vice President and Chief Financial Officer. Peters, a CPA, brings over 30 years of financial leadership including 20 years in publicly traded companies. Most recently Peters held the position of Chief Financial Officer with multi-national Burlington Industries. Peters responsibilities as Chief Financial Officer at Red Hat will include accounting, finance, treasury, tax, credit and investor relations.Charlie is a seasoned professional with a unique depth and breadth of experience in international finance and publicly traded companies that will help lead Red Hats next phase of growth, said Matthew Szulik, Chairman and Chief Executive OfficerPeters began his career with Price Waterhouse in 1973, serving in Boston and London in the audit division. In 1982, he joined GenRad, Inc., an NYSE-listed multi-national manufacturer of scientific test equipment
Cargill is a multi-national corporation who, like any other corporation, is interested in profits. If they can gain some profit from organics, they will just as they will gain profits from agri-business and gmo crops. This doesnt mean they are concerned with soil health or with the environment or with feeding the world. Their motivation is profit. If there is something to be had from sourcing organic cacoa from Africa ..... they will be there doing just that. Of course, there has been a lot of pressure for Cargill to source their cacoa from outfits that are not using child-slavery .....and they are now doing that .... but the initiative to do so did not come from them. They had to be made aware from groups whose main focus was not profit, but accountability and equality ...
Sunit Dhawan Tribune News Service Rohtak, April 12 After having worked at a couple of multi-national companies (MNCs) for nearly a decade, corporate executive Pradeep Singh quit his job and started
These kitting trays feature static dissipative foam that allows for safe transport of PCB and SMT components. We are a multi-national distributor of static control products for the electronics and medical device manufacturing industries.
Regardless of how you feel about how multi-national conglomerates have changed healthcare IT, you must at least acknowledge GE Healthcares size and influence.
Brochures from Paradigm®, the worlds largest multi-national software company focused on analytical and information management solutions for oil and gas resources
Multi-national troops participating in the Eager Lion military exercise conduct combat drills in Jordan. Rough Cut (no reporter narration).
Another lane training exercise, spearheaded by the Ukrainian soldiers was a mock insurgent attack on a checkpoint. The idea behind the exercise was to train their soldiers how to deal with different scenarios involving insurgency tactics. During the exercise a soldier playing the role of an insurgent would try to distract the guard at the checkpoint while other mock insurgents tried to secure a position from which they could attack ...
The EUROGRADUATE project has published its final outcome, its report on Testing the Feasibility of a European Graduate Study.. Readers have before them the results of a remarkable undertaking, one in keeping with other European multi-national inquiries and analyses. Here is an exemplary case of the search for guidance through pathways of data that do not currently exist. Like the histories of early European explorers, it is reflective of the best of navigational planning. Where are we going and how, the planners ask? What are the unknown territories like? How long will it take to arrive at and return from our destination? What provisions do we need? Who will be in charge? Who will comprise the crew? What are their tasks? These are not unfamiliar questions in European history. They are all asked well in advance of the departure of ships. In fact, the answers to these questions provide benchmarks for determining whether the voyage will take place at all.. Thus, a feasibility study, managed by four ...
Coupled with heliums attributes, which are impossible to replicate, and numerous new applications for helium currently being evaluated, heliums status as a highly strategic and valuable commodity is clearly established.. Helium is currently produced as a by-product of natural gas processing and LNG production, with global supply concentrated among six large multi-national companies. In contrast to most of the existing helium production facilities, Helium Ones assets are standalone helium projects that have the potential to materially enhance global helium reserves.. ...
My Papa was born to a poor family. He lost his father when he was only a kid and never had the chance to finish primary school. Determined to have a better life, he left his hometown in Liloan, Southern Leyte and headed South in the island of Mindanao. He worked as a laborer in various companies until luck smiled down on him and he got hired in a multi-national beverage company in Davao. While we were growing up, my Papa worked very hard just to send all four of us to school. He was the disciplinarian type and when we were smaller, he would discipline us when he can. A very responsible father who wants to provide for his family, I can say that he has really done his best. I am very thankful for everything that he has done for us although I miss the times that he could have been there but he cannot because he has to work. Now, he just retired from work. I hope that he will be able to enjoy his time with my mother, now that all of us are grown-ups and have families of our own too. I miss my Papa. ...
NORWOOD, MA--(Marketwired - January 29, 2018) - Multi-national Phase 2b is designed to provide clear evidence of clinical benefit of lenabasum (formerly known as anabasum) in patients with CFStudy will enroll ~415 participants with CF 12 years of age and older regardless of underlying CFTR mutation, infection, or background medicationsFirst...
Mr. Katzenberg landed flat on his back after Michael Eisner threw him out of Walts Kingdom. But he picked himself up and built an enterprise that has generated not only a lot of entertaining features, but provided lots of work for a lot of animation artists. Hes performed a corporate high-wire act for nearly twenty years, something that even Pixar -- now a division of a huge multi-national conglomerate -- failed to achieve. And the fact that Jeffrey hasnt sold DreamWorks Animation to one of the other entertainment conglomerates says more about our current economy than it does about him. (Pixar was purchased by the Disney Company for a premium price years before the 2008 financial meltdown. If the timing had been different, it quite possibly would have remained a stand-alone animation studio in the same way that DWA is today ... or made Mr. Jobs and his heirs a lot less money at the point of purchase ...
McLibel is an extraordinary tale of how two ordinary people, gardener Helen Steel and postman Dave Morris stood against the multi-national giant, McDonal...
We avoided a few names when choosing for my son based on a multitude of nicknames! The two in particular were Michael (Mick, Mike, Mickie etc) and Patrick (Pat, Paddy, Pa etc). That mightnt bother some people but we just wanted to call him something that didnt have loads of obvious nicknames - I know people will get one or two no matter what you call them but we figured wed avoid the obvious ones! Another thing we avoided was names that would be unpronounceable to foreigners. Both of us work for multi-national companies and so its not beyond possibility that well be sent abroad at some stage in the future - after hearing yanks pronouncing some irish names (and we all speak the same language) we were put right off the very irish versions of some names. Again, not something that would bother everyone but it wrecks my head when peoples names are mis-pronounced. If you dont want something too popular, check out the list of baby names on the CSOs website ...
We work with all size companies, from 25 employees at a single location to thousands working for a multi-national concern. Since our founding in 1995 our offerings have evolved based on client needs and state-of-the-art services. Along the way we have seen all shapes and sizes of networking puzzles, security challenges and demanding business support.. Our success can be attributed to our ability to solve complex problems and maintain networks and infrastructure that mean the world regardless of the company size. This has led us to form many partnerships with service providers and distributors that provide you resilient operations without worrying about the day-to-day obligations.. What customers tell us is that our experience counts. With Synapse Networks comes a consultative approach, a comprehensive understanding of your needs and integrity without compromise. The greatest benefit of all is to build on strong relationships to continuously add value.. ...
My QA career started with Pharmaco LSR in Suffolk from 1990 to 1995. The role included inspecting and auditing pre-clinical safety studies; acting as Deputy Team Leader and Training coordinator. From September 1995 until December 1998 I was employed as the Laboratory and Clinical Quality Manager at the Harefield site of Schering-Plough Animal Health, formerly Mallinckrodt Veterinary. The role included monitoring the GLP compliance of the Harefield site, inspecting contract facilities, monitoring GMP aspects of clinical trials vaccine production and auditing veterinary GCP clinical studies across Europe.. Since December 1998 I have been self employed as a QA consultant. I have worked with a range of companies, providing services in GLP, VICH GCP and ICH GCP related activities. These companies include large multi-national pharmaceutical companies (in both pharmaceuticals and biologics) involved in human health or animal health, smaller human and animal health companies, agrochemical companies and ...
SAN DIEGO--(BUSINESS WIRE)-- Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) announced today that its partner Pfizer, Inc. (NYSE:PFE) has granted a sublicense to a multi-national pharmaceutical
The International Network of Obstetric Survey Systems (INOSS) is a multi-country collaboration formed to facilitate studies of uncommon and severe complications of pregnancy and childbirth. Collaborations such as INOSS offer many benefits in the study of rare complications. The use of uniform case definitions, common datasets, specifically collected detailed data and prospectively agreed comparative and combined analyses all add to the validity of studies and their utility to guide policy and clinical practice and hence improve the quality of care. Such multi-national collaborations allow for the conduct of robust studies less subject to many of the biases attributed to typical observational studies. For very rare conditions such collaborations may provide the only route to providing high quality evidence to guide practice. Clinicians and researchers conducting studies into rare and severe complications should consider working through a network such as INOSS to maximize the value of their research.
Now, patience over the alien situation has run out. Control over the aliens has been given to Multi-National United (MNU), a private South African company uninterested in the aliens welfare and only in the weapons they bring and the millions they stand to make from obtaining them. Since activation of the weaponry requires alien DNA, MNU has failed in this and tension between the aliens and the humans reaches a boiling point when an MNU field operative, Wikus van der Merwe (Sharlto Copley), contracts a mysterious virus that begins altering his DNA. Wikus quickly becomes the most hunted man in the world, as well as the most valuable - he is the key to unlocking the secrets of alien technology. Ostracized and friendless, there is only one place left for him to hide: District 9 ...
Benchmark Email is a multi-national email marketing company with offices in Long Beach, CA and Gurgaon, India providing solutions for small businesses and corporations. It also provides technical and marketing support from India to both the US and the World.
One of the most concerning business trends today is the increasing number of misleading facts or data that triggers the wrong managerial reaction.. Case in point: a large multi-national company conducts an all-employee survey and reports better-than-expected results even amid a year of layoffs, management changes and competitive pressures. Leadership feels confident in their approach and changes nothing. Within three months, several key executives leave, the union stages a walk- out, the stock plummets and key new product introductions are delayed.. What happened? The results documented in the survey were not accurate. Employees, knowing the future is uncertain if not shaky, chose to answer questions positively fearing for their jobs. Leadership, lacking curiosity and knowing the results went against what they were seeing daily in the workplace ignored reality.. The effect: a major talent drain within six months, delayed programs, and reduced revenue and share targets.. Case in Point: Sales of a ...
Mason, OH Aniara Corporation, a multi-national distributor of diagnostic and research agents, as well as screening tools, has strengthened its commitment to meeting today s highest standards for pro...
My Papa was born to a poor family. He lost his father when he was only a kid and never had the chance to finish primary school. Determined to have a better life, he left his hometown in Liloan, Southern Leyte and headed South in the island of Mindanao. He worked as a laborer in various companies until luck smiled down on him and he got hired in a multi-national beverage company in Davao. While we were growing up, my Papa worked very hard just to send all four of us to school. He was the disciplinarian type and when we were smaller, he would discipline us when he can. A very responsible father who wants to provide for his family, I can say that he has really done his best. I am very thankful for everything that he has done for us although I miss the times that he could have been there but he cannot because he has to work. Now, he just retired from work. I hope that he will be able to enjoy his time with my mother, now that all of us are grown-ups and have families of our own too. I miss my Papa. ...
My Papa was born to a poor family. He lost his father when he was only a kid and never had the chance to finish primary school. Determined to have a better life, he left his hometown in Liloan, Southern Leyte and headed South in the island of Mindanao. He worked as a laborer in various companies until luck smiled down on him and he got hired in a multi-national beverage company in Davao. While we were growing up, my Papa worked very hard just to send all four of us to school. He was the disciplinarian type and when we were smaller, he would discipline us when he can. A very responsible father who wants to provide for his family, I can say that he has really done his best. I am very thankful for everything that he has done for us although I miss the times that he could have been there but he cannot because he has to work. Now, he just retired from work. I hope that he will be able to enjoy his time with my mother, now that all of us are grown-ups and have families of our own too. I miss my Papa. ...
We are home to over 8,500 local and multi-national companies, and Six Fortune 500 companies operate global headquarters in Irving.
Shanghai SINCH Pharmaceuticals Tech. Co., Ltd (hereinafter called SINCH Pharmaceuticals), is a leading pharmaceutical company specialized in the field of medicine research & development. Since its establishment in the year of 2006, SINCH Pharmaceuticals has been focusing on developing high-quality chemical compound synthesis, herbal and natural medicines for senile and chronic diseases treatment. SINCH Pharmaceuticals possesses a strong R&D team of thirteen dedicated scientists, among which four of them hold PHD degree, while ten of them have education background of BS or above. The company is managed by a group of experts who had abundant working experiences in first-rank multi-national pharmaceutical enterprises. Its location in Wujiaochang High-tech Industry Park, a region in which most renowned universities of Shanghai gathered, allows SINCH Pharmaceuticals to build a stable cooperation relationship in drug research and development with many neighboring chemical institutes. SINCH ...
Genomic sequencing recently reported by two multi-national research teams presents both challenges and opportunities in the battle against malaria.
What are the typical reasons behind cross-border alliances? What are some of the government influences that impact MNCs (Multi-National.
Retail Pro International is a global leader in retail software. For over 25 years the company delivered its retail management products and unmatched global support services to become a proven solution for serious retailers everywhere. Today, Retail Pro solutions are recognized world-wide for their unparalleled flexibility, functionality, multi-national and multi-language capabilities.
Investigation of the structure of lipid A from Actinobacillus actinomycetemcomitans strain Y 4 and human clinical isolate PO 1021-7
... LAS VEGAS Feb. 22 2017 /- &nb... When I lost Ron four years ago I knew that his legacy in addition t...Dr. Gilbert 52 was shot and killed by a patient in a tragic case of ... Reckitt Benckiser approached our company in 2014 expressing an inter...,Company,Of,Murdered,California,Urologist,,Absorption,Pharmaceuticals,,Files,Suit,Against,Multi-National,Maker,Of,Everyday,Household,Products,For,Trade,Secret,Theft,And,Fraud,medicine,advanced medical technology,medical laboratory technology,medical device technology,latest medical technology,Health
This is a Randomized, Double-blind, Multi-center, Multi-national Trial to Evaluate the statistical equivalence of efficacy, safety and immunogenicity of SAIT101 Versus Rituximab as a First-line Immunotherapy Treatment in asymptomatic patients with Low Tumor Burden Follicular Lymphoma. Patients will be randomized in a 1:1 ratio to receive study drug once a week for 4 weeks, and will then be followed up for up to 52 weeks after the first dose. Randomization will be stratified by inclusion in the PK/PD sub-population and Follicular lymphoma international prognostic index 2 (FLIPI-2) score.. Visits are scheduled at Weeks 1, 2, 3, and 4 (study drug infusion visits), and then at Weeks 5, 12, 20, 28, 36, and 52 (i.e., End of Study [EOS]). Efficacy response assessments will be performed at Weeks 12 and 28, while safety assessments will continue until EOS.. The primary objectives is To compare the efficacy of SAIT101 with rituximab licensed in the European Union (hereafter designated MabThera®, brand ...
Longtime National and Ohio Farmers Union ally, the Coalition for a Prosperous America is holding a webinar on July 22 titled, Country of Origin Labeling: How Multinational Agribusinesses are Attacking This Law .. Bill Bullard, CEO of R-CALF USA will discuss the importance of COOL and how the COOL legislation, if defeated, could affect the food on your table. Michael Stumo, CEO of CPA will moderate the event which is free. Follow this link to register for the webinar.. Along with information about COOL and its benefit for family farmers and consumers, webinar viewers will receive ideas about how they can work to preserve COOL.. The Coalition for a Prosperous America is a nonprofit organization representing the interests of 2.7 million households through our agricultural, manufacturing and labor members. Our board and our membership includes Republicans, Democrats, Independents, Conservatives and Liberals.. Joe Logan, president of the Ohio Farmers Union is a member of the CPA board executive ...
Monoclonal antibody against Aggregatibacter actinomycetemcomitans serotype b expressed by for use in Western Blot against gram-negative bacteria
TRACK-HD was a multi-centre, multi-national, prospective, observational study of pre-manifest and early Huntingtons disease (HD) with a control group of volunteers not carrying the HD mutation. The goal of the project was to contribute essential methodology that will form the basis for clinical trials in pre-manifest and early HD. TRACK-HD complemented existing observational studies (e.g., Predict-HD, PHAROS, COHORT), sharing some features, but also having areas of unique emphasis.. The UBC site recruited 90 subjects including 30 control subjects, 30 asymptomatic pre-manifest HD gene carriers and 30 subjects with early symptoms of HD (stage 1 or 2). All subjects were assessed using the TRACK-HD battery at baseline, 1 year, 2 years, and 3 years. Following the fourth visit (3 year assessment), the TRACK-HD study will be completed, and the 30 subjects with early symptoms of HD will be invited to enroll in the MITIGATE-HD Study.. The MITIGATE-HD study is a single center Phase ...
I recently returned from the North American South Asian Bar Association (NASABA) conference. Out of all the sessions I attended over the course of the three day event by far and away the most thought provoking and certainly the one that sparked the most intense and combative question and answer session focused on the pros and cons of the opening up of the Indian legal services sector to foreign law firms. The position as it stands as of now is that the practice of law in India is governed by the Advocates Act of 1961. Foreign law firms are simply not allowed to engage in the practice of law in India.. Over the last decade we have seen the Western legal community look to find increasingly creative ways to circumvent these restrictions. A number of large multi-national accounting firms have set up offices in India and are clearly providing legal services to their clients, employing large numbers of Indian lawyers. Several foreign law firms have Liaison offices (permitted under current ...
In absence of patient-level databases, multi-national, retrospective chart review studies can be undertaken to provide robust naturalistic data to inform evaluations of treatment patterns, resource utilization, costs of care, clinical outcomes and safety.
Are you passionate about conducting research to drive real behavioral change and inform front line managers and leaders in making more effective decisions? Would you love to see your research in practice, impacting Amazonians globally and improving the employee experience? If so, you should consider joining the Amazon Web Services (AWS) Organizational Effectiveness and Science team.AWS is a dynamic, growing business unit within Amazon.com. Since early 2006, AWS has provided companies of all sizes with an infrastructure platform in the cloud. Today, AWS provides a highly reliable, scalable, low-cost infrastructure platform in the cloud that powers millions of active monthly customers from start-ups to multi-national corporations to governments.In this role, you will lead the research strategy to evaluate, diagnose, understand, and surface drivers and moderators for key, global research streams. These include (but are not limited to) productivity, innovation, decision-making, and Amazon culture. ...
In my role as Counsel in our Dubai Corporate and M&A Group, I act for international and domestic clients in the corporate, M&A and banking and finance domain. My particular focus is on multi-national and cross-border transactions.
The U.S. Coast Guard offloaded 2,500 pounds of cocaine valued at $37 million that was seized in a historic multi-national operation in the Caribbean, officials said Tuesday. (Jan. 28)
Poggenpohl asserts that design research is developed through a typology within academic and business contexts, and follows different research theories and strategies. Such issues in design collaboration are explored in-depth, with essays on an inter-institutional academic project, cross-cultural learning experiences, and a multi-national healthcare project, demonstrating the importance of shared values, interdisciplinary negotiated process and clear communication for tomorrows designers.. - Design integrations. ...
This is a one-day course to introduce and develop understanding of ferns and to develop skills in their identification. It is aimed at beginners. The number of species in this group and the apparent similarity between many of them can make them daunting. The terminology itself can seem impenetrable. However, this course is intended to show that, with a little help, these obstacles can be overcome, opening the door to a fascinating group of organisms able to tell us much about the evolution of plants and the environments in which they are found.. This course will be delivered by Dr Paul L Smith BSc MIEEM CEnv. Paul is a formally trained botanist who has practiced in the academic and consultancy sectors for 40 years including work for Local Authorities, Natural England, Multi-national consultancies, and the Wildlife Trusts. Paul has a special interest in solving botanical conflicts with development and land use change. You can find out more about Pauls commercial work here.. ...
Jerusalem, Israel, - Gamida Cell announced today additional analyses for the Phase II/III, multi-center, multi-national, historical cohort-controlled study to evaluate efficacy and safety of StemEx® as an alternative transplantation treatment for patients with high risk leukemia and lymphoma. Twenty-five bone marrow transplant centers worldwide treating ...
T&B Petroleum - The first Brazilian magazine dedicated to oil, gas and biofuel market. Each issue contains vital information compiled by the intelligence units of T&B Petroleum: following the movements of the industrys market players, economic indicators, government regulators, and sector engineers and scientists. T&B Petroleum is a must for any business entering Brazils market and an ally to the industrys national and multi-national companies that regularly appear in its pages.
BPE Solicitors is headquartered in Cheltenham with access points in London, Cirencester, Bristol and Oxford. It has more than 130 staff including 70 fee-earners.. Many clients have been retained for decades and the firm has supported young businesses in their growth to become multi-million pound, multi-national operations.. BPE Solicitors is an entrepreneurial business working with like-minded businesses and individuals, supporting businesses through their lifecycle, from starting up and structuring to development through growth, joint ventures, buying and selling or floating on the stock market.. bpe.co.uk. ...
North Atlantic Fishing Company is a British fishing company established in 1984 that owns and operates pelagic freezer-trawlers catching mackerel, herring, horse mackerel and blue whiting for world-wide export markets. The company is a part of the family owned Cornelis Vrolijk multi-national group.
We are home to over 8,500 local and multi-national companies, and Six Fortune 500 companies operate global headquarters in Irving.
Following the establishment of the Dutch East India Companys initial settlement at the Cape of Good Hope in 1652, it became home to a large population of vrijlieden, also known as vrijburgers (free citizens).[9] The earliest vrijburgers were Company employees who applied for grants of land and permission to retire in South Africa as independent farmers.[9] Most were married Dutch citizens who committed to spend at least twenty years on the African continent.[9] In exchange they received plots of thirteen and a half morgen apiece, a twelve-year exemption from property taxes, and loans of seeds and agricultural implements.[9][10] Reflecting the multi-national character of the Companys workforce and overseas settlements, smaller numbers of German and French Huguenot immigrants were also allowed to settle in South Africa, and by 1691 over a quarter of the Capes European population was not ethnically Dutch.[11] Nevertheless, there was a degree of cultural assimilation due to intermarriage, and ...
Cross-sector collaborations to perform R&D are on the increase, but they do involve various risks for each of the partners. Project risks in such ventures are explored through a case study, a successful collaboration involving an Australian Cooperative Research Centre and Ciba Vision, a division of the Swiss multi-national Novartis. The analysis examines the projects success factors and its risks. The reputation of researchers, the development of mutual trust among the partners, and the importance of credible commitments made at project initiation are three key factors contributing to the success of commercially focused R&D collaborations ...
Any intelligent person forced to take part in an office team-building exercise knows how easy it would be to slip from controlled corporate rage to homicide. The creators of Severance understand that feeling. In place of traditional slasher film targets (such as obnoxious teenagers) they have substituted the people we most want to see mutilated and murdered: co-workers.. When their bus breaks down somewhere in an Eastern European forest, several sales employees of the multi-national Palisade Defence have to schlep their belongings to the nearest hotel. There they await instructions from the American executive who planned their trip. The hotel turns out to be a moldy inn equipped with no amenities except weird pie. And every step outside the place lands the unhappy employees in (often excruciating) peril. Acting Talent ...
Xebec Adsorption Inc. is a global provider of gas generation, purification and filtration solutions for the industrial, energy and renewables marketplace. Its customers range from small to multi-national corporations and governments looking to reduce their carbon footprints. Headquartered...
I grew up in Texas on a cattle ranch. I was fortunate to be raised by my grandparents after the death of my mother. My grandmothers best friend was Betty Moorman, a wealthy White lady, who in effect adopted my family. So I had the interesting life of growing up poor, but knowing what it was like to be rich. I went to private high school, paid for by Betty. I excelled in school, and received an academic scholarship to Southern Methodist University in Dallas. After graduating I worked in as an electrical engineer, before getting into sales. In 1992 I bought my own sales company, and built a multi-national six office organization, which I sold in 1996. Presently I am an executive in an IT consulting firm, and serve on the board of The Adoption Exchange in St. Louis. In short, I know what it is like to be poor, to be rich, and to give back. This blog is meant to showcase the true meaning of being a proud Black Conservative in America. If you like what you read, please click Follow This Blog or ...
I grew up in Texas on a cattle ranch. I was fortunate to be raised by my grandparents after the death of my mother. My grandmothers best friend was Betty Moorman, a wealthy White lady, who in effect adopted my family. So I had the interesting life of growing up poor, but knowing what it was like to be rich. I went to private high school, paid for by Betty. I excelled in school, and received an academic scholarship to Southern Methodist University in Dallas. After graduating I worked in as an electrical engineer, before getting into sales. In 1992 I bought my own sales company, and built a multi-national six office organization, which I sold in 1996. Presently I am an executive in an IT consulting firm, and serve on the board of The Adoption Exchange in St. Louis. In short, I know what it is like to be poor, to be rich, and to give back. This blog is meant to showcase the true meaning of being a proud Black Conservative in America. If you like what you read, please click Follow This Blog or ...
Cross-sector collaborations to perform R&D are on the increase, but they do involve various risks for each of the partners. Project risks in such ventures are explored through a case study, a successful collaboration involving an Australian Cooperative Research Centre and Ciba Vision, a division of the Swiss multi-national Novartis. The analysis examines the projects success factors and its risks. The reputation of researchers, the development of mutual trust among the partners, and the importance of credible commitments made at project initiation are three key factors contributing to the success of commercially focused R&D collaborations ...
Lisa Jackson, former head of the EPA and current Apple executive, explains how the company tries to minimize its carbon footprint in its multi-national supply chain.
T&B Petroleum - The first Brazilian magazine dedicated to oil, gas and biofuel market. Each issue contains vital information compiled by the intelligence units of T&B Petroleum: following the movements of the industrys market players, economic indicators, government regulators, and sector engineers and scientists. T&B Petroleum is a must for any business entering Brazils market and an ally to the industrys national and multi-national companies that regularly appear in its pages.
we all are, and we all arent tim russert.... corporate hegemony controls the media, but today thats like saying, The sun rises in the east.. The nuance, a word and concept reviled by the corporate, multi-national media conglomerates, is that russert-and I mean his position or function as much as himself-are primarily servants to the power elite, shills, ventriloquists dummys even-spewing the misinformation handed them. Theyve been disciplined into learned helplessness by their ever more powerful corporate masters.. How many of us get up every day hoping for the opportunity to make the slightest difference, all the while knowing we are making our morning commute in pro-forma fashion to stoke the beast?. I despise russert and his ilk as much as anybody, I also know my fare-trade, g-local, white-chocolate mocha, extra shot, productivity enhancing morning addiction is as equally a symbol of my own daily acquiescence to the big lie as russerts gaping maw.. Posted by: staplegunn at April 26, ...
Aggregatibacter actinomycetemcomitans • Aim toothpaste • Akers' clasp • Alberta Dental Association and College • Alfred Fones ...
Other capnophilic pathogens occur in the gram-negative Aggregatibacter spp. found in the mouth (e.g. Aggregatibacter ... Bhattacharjee, MK; Childs (June 2011). "Sensitivity of the periodontal pathogen Aggregatibacter actinomycetemcomitans at mildly ...
nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Aggregatibacter (from the Latin, "aggregare", meaning "to come together"). Chung; et al. (2008). "Actinobacillus ... and clinical significance of haemophilus and aggregatibacter species with host specificity for humans". Clinical Microbiology ... Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. ...
Aggregatibacter actinomycetemcomitans and E. coli. That is, they are toxic to leukocytes as well as many other cell types and ...
Aggregatibacter aphrophilus expresses a HMW1C homologue. The substrate for the HMW1C homologue of Aggregatibacter aphrophilus ... The Aggregatibacter aphrophilus glycosyltransferase is important for the adhesion of the bacterium to epithelia. In Haemophilus ... "Unconventional N-Linked Glycosylation Promotes Trimeric Autotransporter Function in Kingella kingae and Aggregatibacter ...
Aggregatibacter actinomycetemcomitans Prevotella intermedia Eubacterium spp. Treponema spp. Porphyromonas gingivalis ...
nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Aggregatibacter actinomycetemcomitans (Klinger, 1912) Nørskov-Lauritsen and Kilian, 2006 - family Pasteurellaceae. A Gram- ... Henderson B, Ward JM, Ready D (October 2010). "Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* ... finally being assigned to Aggregatibacter. Alkalispirochaeta sphaeroplastigenens (Vishnuvardhan Reddy et al. 2013) Sravanthi et ...
... (transferred to genus Aggregatibacter) is a bacterium. H. segnis can be cultured on chocolate agar. Nørskov- ... Lauritsen N (April 2014). "Classification, identification, and clinical significance of Haemophilus and Aggregatibacter species ...
Iron- regulated sRNAs JA01- JA04 were identified in related Aggregatibacter. It is an analog to PrrF and RyhB RNAs. HrrF is ...
As well as Aggregatibacter actinomycetemcomitans being associated with this, the synergism of the disease also accounts for ... High levels of Aggregatibacter (or Actinobacillus) actinomycetemcomitans and, in some populations, Porphyromonas gingivalis. ... This is due to the suppression of serum IgG2 and antibody against Aggregatibacter actinomycetemcomitans found in smokers. ... A significant reduction in the aggregatibacter actinomycetemcomitans count following PDT suggests that the use of PDT in ...
The in vivo Th17 and Treg immune response to Aggregatibacter actinomycetemcomitans. Mol Oral Microbiol 2017;32:490-99. Junka A ... ". "The in vivo Th17 and Treg immune responses to Aggregatibacter actinomycetemcomitans". Sedghizadeh, Parish P.; Chen, Meng- ...
Aggregatibacter actinomycetemcomitans is a Gram-negative coccobacillus prevalent in subgingival plaques. Acinetobacter strains ...
Aggregatibacter actinomycetemcomitans has been identified as being of note in periodontal disease. The genus is typically the ...
Aggregatibacter actinomycetemcomitans is a gram negative coccobacillus which is prevalent in subgingival plaques. Acinetobacter ...
CSIs have also been found that are specific for Aggregatibacter and Mannheimia , two clinically relevant genera. The ... Other pathogenic members of the family Pasteurellaceae include Aggregatibacter, Mannheimia, Pasteurella, and Actinobacillus ... One proposed clade includes Aggregatibacter, Pasteurella, Actinobacillus succinogenes, Haemophilus influenzae, Haemophilus ...
Haemophilus parahaemolyticus Haemophilus parainfluenzae Aggregatibacter Aggregatibacter actinomycetemcomitans (previously ... Aggregatibacter paraphrophilus (previously Haemophilus aphrophilus) Aggregatibacter segnis Cardiobacterium Cardiobacterium ... However, taxonomic rearrangements have changed the A to Aggregatibacter species and the H to Haemophilus species to reflect the ... HACEK is an abbreviation of the initials of the genera of this group of bacteria: Haemophilus, Aggregatibacter (previously ...
... was a species of Haemophilus, but the name has recently been changed to Aggregatibacter aphrophilus. It ...
Research in 2004 indicated three gram negative anaerobic species: Aggregatibacter actinomycetemcomitans, Porphyromonas ...
Slots is responsible for discovering the role of Aggregatibacter actinomycetemcomitans (previously Actinobacillus ...
... is produced by Aggregatibacter actinomycetemcomitans, a Gram-negative oral bacterium, when it needs to detach and ... Aggregatibacter actinomycetemcomitans. The bacteria secrete Dispersin B to release adherent cells from a mature biofilm colony ...
HrrF RNA NrrF RNA Aggregatibacter iron-regulated sRNA Wilderman PJ, Sowa NA, FitzGerald DJ, FitzGerald PC, Gottesman S, Ochsner ...
... a type of agar plate medium used in microbiological testing to select for Aggregatibacter actinomycetemcomitans (A.a.). It was ...
Two major clades are formed within this Pasteurellales: Clade I, encompassing Aggregatibacter, Pasteurella, Actinobacillus ...
Actinobacteria spp Anaerococcus spp Actinomyces naeslundii Aggregatibacter actinomycetemcomitans Atopobium vaginae Bacteroides ...
Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans; the latter functional defects were improved by treating the ...
Medically important CDT producers include: Haemophilus ducreyi (chancroids) Aggregatibacter actinomycetemcomitans ( ...
RhyB RNA PrrF RNA HrrF RNA Aggregatibacter iron-regulated sRNA Neisseria sigma-E sRNA Neisseria RNA thermometers Neisseria ...
H+ The enzyme from bacterium Aggregatibacter actinomycetemcomitans participates in the biosynthesis of the serotype c-specific ...
Iodobacter phage phiPLPE Species Aeromonas phage 56 Aggregatibacter phage Aaphi23 Bdellovibrio phage phi1402 Bdellovibrio phage ...
Nov., Aggregatibacter aphrophilus comb. Nov. And Aggregatibacter segnis comb. Nov., and emended description of Aggregatibacter ... Aggregatibacter is a genus in the phylum Proteobacteria (Bacteria), which contains three species, namely: A. ... Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. Nov., comb. ...
nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Type strain of Aggregatibacter actinomycetemcomitans at BacDive - the Bacterial Diversity Metadatabase. ... Jorth P, Whiteley M (December 2010). "Characterization of a novel riboswitch-regulated lysine transporter in Aggregatibacter ... Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans) is a Gram-negative, facultative ...
Genomic DNA from Aggregatibacter actinomycetemcomitans strain HK1651 TypeStrain=False Application: ... nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen and Kilian 2006 ATCC® 700685D-5™ dried At least 5 µg in ... Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen and Kilian 2006 (ATCC® 700685™) Add to ...
Aggregatibacter aphrophilus ATCC ® 33389-MINI-PACK™ Designation: NCTC 5906 TypeStrain=True Application: ATCC ® 33389-MINI-PACK ... nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Aggregatibacter aphrophilus (Khairat 1940) Nørskov-Lauritsen and Kilian 2006 ATCC® 33389-MINI-PACK™ frozen 6 ready-to-use vials ... Aggregatibacter aphrophilus (Khairat 1940) Nørskov-Lauritsen and Kilian 2006 (ATCC® 33389-MINI-PACK™) Strain Designations: NCTC ...
Genome sequence of Aggregatibacter actinomycetemcomitans serotype c strain D11S-1.. Journal. J Bacteriol 191:7378-9 (2009). DOI ... Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Aggregatibacter. Data source. GenBank (Assembly ...
Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The ... Gangliosides Block Aggregatibacter Actinomycetemcomitans Leukotoxin (LtxA)-Mediated Hemolysis Michael S. Forman, Jason B. ... Forman, M.S.; Nishikubo, J.B.; Han, R.K.; Le, A.; Balashova, N.V.; Kachlany, S.C. Gangliosides Block Aggregatibacter ... Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The ...
Gangliosides block Aggregatibacter Actinomycetemcomitans leukotoxin (LtxA)-mediated hemolysis.. [Michael S Forman, Jason B ... Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The ...
Aggregatibacter actinomycetemcomitans e Fusobacterium nucleatum são microrganismos gram-negativos presentes nos processos ... Aggregatibacter actinomycetemcomitans. Fusobacterium nucleatum. Biofilme subgengival. Gengivite. Periodontite crônica. Resumo ... Aggregatibacter actinomycetemcomitans. Fusobacterium nucleatum. Chronic periodontitis. Gingivitis. Subgingival biofilm. Resumo ... Aggregatibacter actinomycetemcomitans e Fusobacterium nucleatum são microrganismos gram-negativos presentes nos processos ...
Mismatch repair - Aggregatibacter actinomycetemcomitans D11S-1 [ Pathway menu , Organism menu , Pathway entry , Download KGML ...
... ... reports on a fatal case of a previously well 42-year-old alcoholic woman with infective endocarditis caused by Aggregatibacter ...
Putative Aggregatibacter actinomycetemcomitans NUM4039 RM systems. Ref: Takada,K. et al. unpublished. REBASE ref # 21571. Complete sequence: 2,382,853 bp. GenBank #: AP014520. REBASE acronym: Aac4039. Org_num: 16983. All begin AANUM_. ...
Putative Aggregatibacter actinomycetemcomitans IDH781 RM systems. Ref: May,A.C. et al. unpublished. REBASE ref # 23071. Complete sequence: 2,291,252 bp. GenBank #: CP016553. REBASE acronym: Aac781. Org_num: 20083. All begin BBH51_. ...
After that, the surface of dental implants was inoculated with Aggregatibacter actinomycetemcomitans (A.a.) strains for 4 days ... Depois disso, a superfície dos implantes dentários foi inoculada com cepa de Aggregatibacter actinomycetemcomitans (A.a.) por 4 ... Adesão de células osteoblásticas em superfícies de implantes contaminadas por Aggregatibacter actinomycetencomitans e tratadas ... Osteoblastic cell adhesion on implant surfaces contaminated by Aggregatibacter actinomycetencomitans and treated by ...
... It has been a long-held supposition of many doctors and researchers that dental ... Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid ... Aggregatibacter actinomycetemcomitans (Aa), is one of a number of organisms contributing to periodontal gum disease that can ...
nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... R. C. V. Casarin, E. D. Ribeiro, F. S. Mariano, F. H. Nociti, M. Z. Casati, and R. B. Gonçalves, "Levels of Aggregatibacter ... Aggregatibacter actinomycetemcomitans (Aa) is a gram-negative coccobacillus, facultative anaerobe, closely associated with the ... S. C. Kachlany, "Aggregatibacter actinomycetemcomitans leukotoxin: from threat to therapy," Journal of Dental Research, vol. 89 ...
cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Aggregatibacter › ... tr,X2JQV5,X2JQV5_AGGAC Oxaloacetate decarboxylase alpha subunit,putative OS=Aggregatibacter actinomycetemcomitans HK1651 OX= ...
Aggregatibacter explanation free. What is Aggregatibacter? Meaning of Aggregatibacter medical term. What does Aggregatibacter ... Looking for online definition of Aggregatibacter in the Medical Dictionary? ... Here we report a case of the brain abscess caused by Aggregatibacter aphrophilus.. Aggregatibacter aphrophilus misidentified as ... Aggregatibacter. Ag·gre·ga·ti·bac·ter. (agrĕ-gati-baktĕr) Newly assigned name of a genus of gram-negative rods formerly called ...
... Ihalin, Riikka Umeå University, ... Our aims were to determine the frequency of ChoP display among Aggregatibacter actinomycetemcomitans strains, to clarify which ... Aggregatibacter actinomycetemcomitans, Serotypes, Periodontitis, Phosphorylcholine, Fimbriae, Flp1, C-reactive protein, Serum ...
IntroductionGram-negative Aggregatibacter actinomycetemcomitans is recognized as an important periodontal pathogen. A striking ... IntroductionGram-negative Aggregatibacter actinomycetemcomitans is recognized as an important periodontal pathogen. A striking ...
In Vitro Cytotoxicity and Leukotoxin Neutralization of Essential Oil from Origanum vulgare against Aggregatibacter ...
... the Gram-negative Aggregatibacter actinomycetemcomitans. For readers with an interest in taxonomy, this microbe was originally ... Aggregatibacter actinomycetemcomitans: A Unique Exotoxin-Producing Oral Bacterium by Pedro Valero-Guillén ... Zijnge V, Kieselbach T, & Oscarsson J (2012). Proteomics of protein secretion by Aggregatibacter actinomycetemcomitans. PloS ... the Gram-negative Aggregatibacter actinomycetemcomitans. For readers with an interest in taxonomy, this microbe was originally ...
Antibiotic susceptibility of Aggregatibacter actinomycetemcomitans JP2 in a biofilm. J Oral Microbiol. 2013; 5. ...
Occurrence of Aggregatibacter actinomycetemcomitans serotypes in subgingival plaque from United States subjects. Mol. Oral ... Comment on "Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in ... Comment on "Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in ... Comment on "Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in ...
What is Aggregatibacter aphrophilus? Meaning of Aggregatibacter aphrophilus medical term. What does Aggregatibacter aphrophilus ... Looking for online definition of Aggregatibacter aphrophilus in the Medical Dictionary? Aggregatibacter aphrophilus explanation ... Keywords: Aggregatibacter aphrophilus, brain abscess, brucella.. Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus ... Brain abscess due to Aggregatibacter aphrophilus and Bacteroides uniformis.. Aggregatibacter aphrophilus brain abscess ...
Among these, Aggregatibacter actinomycetemcomitans (Aa), but not other candidate pathogens, induced hypercitrullination in host ... Aggregatibacter actinomycetemcomitans generates citrullinated autoantigens involved in rheumatoid arthritis through its pore- ... Aggregatibacter actinomycetemcomitans generates citrullinated autoantigens involved in rheumatoid arthritis through its pore- ... Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid ...
The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is a heterotrimeric AB2 toxin capable of inducing ... The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is a heterotrimeric AB2 toxin capable of inducing ... The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is a heterotrimeric AB2 toxin capable of inducing ... Shenker BJ, Boesze-Battaglia K, Scuron MD, Walker LP, Zekavat A, Dlakic M. The toxicity of the Aggregatibacter ...
Suci, P; Kang, S; Gmür, R; Douglas, T; Young, M (2010). Targeted delivery of a photosensitizer to Aggregatibacter ... Biofilm microcolonies of Aggregatibacter actinomycetemcomitans, a periodontal pathogen, were targeted with the multifunctional ... Biofilm microcolonies of Aggregatibacter actinomycetemcomitans, a periodontal pathogen, were targeted with the multifunctional ...
Aggregatibacter actinomycetemcomitans (b) derived from ATCC® 29522™*, SKU: 01175PKWIK-STIK™ 2 PackDETAILS ... Aggregatibacter actinomycetemcomitans (b) derived from ATCC® 29522™*, SKU: 01175LLYFO DISK™DETAILS ...
Variability in the response of human dendritic cells stimulated with Porphyromonas gingivalis or Aggregatibacter ... response of human dendritic cells to stimulation with different concentrations of Porphyromonas gingivalis or Aggregatibacter ...
Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus and H. paraphrophilus ) is part of the normal oropharyngeal flora ... Aggregatibacter aphrophilus in a patient with recurrent empyema: a case report Autoren:. Lasantha Ratnayake William J Olver Tom ... Aggregatibacter aphrophilus in a patient with recurrent empyema: a case report. Zeitschrift:. Journal of Medical Case Reports ... Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus and H. paraphrophilus) is part of the normal oropharyngeal flora ...
  • Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. (wikipedia.org)
  • Recent studies have shown a phylogenetic similarity of A. actinomycetemcomitans and Haemophilus aphrophilus, H. paraphrophilus, and H. segnis, suggesting the new genus Aggregatibacter for them. (wikipedia.org)
  • Nørskov-Lauritsen N, Kilian M. Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. (atcc.org)
  • Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus) is an aerobic gram-negative coccobacillus that belongs to the HACEK (Haemophilus aphrophilus/paraphrophilus, Actino bacillus actinomycetem comitans, Cardiobacterium hominis, Eikenella corrodens and Kingella spp. (thefreedictionary.com)
  • Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus and H. paraphrophilus ) is part of the normal oropharyngeal flora. (springermedizin.de)
  • It is a member of the HACEK group of organisms ( Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella and Kingella ) [ 2 ] and was formerly named Haemophilus aphrophilus or Haemophilus paraphrophilus . (biomedcentral.com)
  • They are part of a group of organisms known as HACEK - Haemophilus , Aggregatibacter , Cardiobacter , Eikenella , and Kingella . (beds.ac.uk)
  • Among these organisms, several Haemophilus species have been reclassified under the genus Aggregatibacter . (beds.ac.uk)
  • Aggregatibacter species are a member of the HACEK group of organisms, which also include Haemophilus , Cardiobacter , Eikenella corrodens , and Kingella . (beds.ac.uk)
  • Here, we present 24 draft genomes for a diverse set of 7 Haemophilus and Aggregatibacter species. (cdc.gov)
  • Classification, identification, and clinical significance of Haemophilus and Aggregatibacter species with host specificity for humans. (cdc.gov)
  • The mediastinitis caused by the association between Haemophilus influenzae and Aggregatibacter aphrophilus has never been described to our knowledge. (springer.com)
  • We report the case of an exceptional combination of Haemophilus influenzae and Aggregatibacter aphrophilus in a patient operated for single bypass which is complicated by mediastinitis the 10th day after the surgical act. (springer.com)
  • The identification of bacterial colonies obtained on Chocolate-isovitalex agar, was on biochemical basis using NH API* strips and bacterial grow in presence of the X-factor and the V-factor on Muller-Hinton agar which allowed the isolation of Haemophilus influenzae and Aggregatibacter aphrophilus . (springer.com)
  • INTRODUCTION: Aggregatibacter paraphrophilus (former name Haemophilus paraphrophilus) is a normal commensal of the oral flora. (ox.ac.uk)
  • Corynebacterium (magenta), Porphyromonas (cyan), Streptococcus (green), and Haemophilus / Aggregatibacter (orange). (pnas.org)
  • Aggregatibacter actinomycetemcomitans (Aa) and Porphyromonas gingivalis (P. (thefreedictionary.com)
  • The microbiological parameters Aggregatibacter actinomycetemcomitans (Aa), Fusobacterium nucleatum (Fn), Porphyromonas gingivalis (Pg) and Prevotella intermedia (Pi) were recorded. (thefreedictionary.com)
  • Estudios demuestran que las enfermedades periodontales estan asociadas a multiples bacterias, tanto gran-negativas como gran-positivas, pero vienen siendo la Porphyromonas gingivales y Aggregatibacter actinomycetemcomitans las principales responsables del inicio y progreso de esta enfermedad, causando asi la destruccion del tejido directamente a traves de productos patogenos tales como endotoxinas y colagenasas o por provocar una respuesta immune. (thefreedictionary.com)
  • Levels of interleukin IL-1[beta], IL-8 and IL-10 in saliva and gingival crevicular fluid (GCF) were evaluated by ELISA, as well as the expression of Porphyromonas gingivalis (Pg), Aggregatibacter actinomycetemcomitans, (Aa) Tannerella forsythia (Tf), and Treponema denticola (Td), by qPCR. (thefreedictionary.com)
  • In this investigation, we analyzed the response of human dendritic cells to stimulation with different concentrations of Porphyromonas gingivalis or Aggregatibacter actinomycetemcomitans. (csic.es)
  • The present cross-sectional study aimed to verify the prevalence of three periodontal pathogens, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, on different groups, with and without teeth. (bvsalud.org)
  • Determinar la presencia de Porphyromonas gingivalis , Tannerella forshytia, Treponema denticola y Aggregatibacter actinomycetemcomitans , en el biofilm subgingival de pacientes diabéticos tipo 2 y relacionarlo con el grado de control metabólico. (bvsalud.org)
  • En el grupo de pacientes estudiados, Treponema denticola y Tannerella forsythia fueron las bacterias más prevalentes (65.2 por ciento), seguida por Porphyromonas gingivalis (17.3 por ciento) y Aggregatibacter actinomycetemcomitans (13 por ciento). (bvsalud.org)
  • Los pacientes con peor control glicémico tuvieron una mayor presencia de Treponema denticola , Tannerella forsythia , Porphyromonas gingivalis y Agreggatibacter actinomycetemcomitans y un aumento en el índice de sangrado al sondaje. (bvsalud.org)
  • To determine the presence of Porphyromonas gingivalis , Tannerella forshytia, Treponema denticola and Aggregatibacter actinomycetemcomitans in subgingival biofilm of patients with diabetes type 2 and to relate it to the degree of metabolic control . (bvsalud.org)
  • In the group of patients examined the most prevalent bacteria were, Treponema denticola and Tannerella forsythia (65.2 percent), followed by Porphyromonas gingivalis (17.3 percent) and Aggregatibacter actinomycetemcomitans (13 percent). (bvsalud.org)
  • The aim of this study was to evaluate the in vitro antimicrobial efficacy of Catharanthus roseus leaf extract against standard strains of periodontal pathogens, Porphyromonas gingivalis , Aggregatibacter actinomycetemcomitans , and Prevotella intermedia . (jidonline.com)
  • Among them, Porphyromonas gingivalis , Aggregatibacter actinomycetemcomitans, and Prevotella intermedia are strongly implicated in the etiology of chronic periodontitis. (jidonline.com)
  • Traditionally, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola have been considered as key organisms of periodontitis, and also Campylobacter rectus, Fusobacterium nucleatum, and Prevotella intermedia are common species in periodontitis. (frontiersin.org)
  • Aggregatibacter actinomycetemcomitans , Enterococcus faecalis, and Porphyromonas gulae were not detected in any of the samples analyzed. (scielo.br)
  • Aggregatibacter actinomycetemcomitans, Enterococcus faecalis e Porphyromonas gulae não foram detectados em nenhuma das amostras pesquisadas. (scielo.br)
  • Greater numbers of both Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans were found in active, destructive periodontal lesions in comparison to non-active sites. (wikipedia.org)
  • As well as Aggregatibacter actinomycetemcomitans being associated with this, the synergism of the disease also accounts for both Capnocytophaga spp and Porphyromonas gingivalis . (wikipedia.org)
  • Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. (mdpi.com)
  • Multi-center research conducted at numerous, prestigious medical institutions in the United States and Denmark, conclude that an oral pathogen, Aggregatibacter actinomycetemcomitans (Aa), is one of a number of organisms contributing to periodontal gum disease that can trigger the production of auto-antibody citrullinated proteins in genetically susceptible (HLA-DRB1) rheumatoid arthritis (RA) individuals. (roadback.org)
  • Introduction Gram-negative Aggregatibacter actinomycetemcomitans is recognized as an important periodontal pathogen. (ovid.com)
  • now demonstrate that a particular periodontal pathogen called Aggregatibacter actinomycetemcomitans ( Aa ) induces changes in neutrophil function, including hypercitrullination of host proteins, an abnormality that is also observed in the joints of patients with rheumatoid arthritis. (sciencemag.org)
  • Biofilm microcolonies of Aggregatibacter actinomycetemcomitans, a periodontal pathogen, were targeted with the multifunctional dodecamer. (uzh.ch)
  • HlyA is the prototype of the repeats-in-toxin (RTX) family, which includes LtxA from Aggregatibacter actinomycetemcomitans , a periodontal pathogen. (asm.org)
  • Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. (asm.org)
  • Aggregatibacter actinomycetemcomitans is an oral and systemic human pathogen that is associated with aggressive forms of periodontitis and with endocarditis ( 16 - 18 ). (asm.org)
  • Aggregatibacter aphrophilus, a commensal of the oro-pharyngeal flora and member of the HACEK group of organisms, is an uncommonly encountered clinical pathogen. (biomedcentral.com)
  • Fimbrial subunit synthesis, secretion and assembly on the surface of the periodontal pathogen Aggregatibacter actinomycetemcomitans are essential for biofilm formation. (microbiologyresearch.org)
  • Aggregatibacter actinomycetemcomitans is a Gram-negative pathogen that is the etiologic agent of localized aggressive periodontitis (LAP) and other systemic infections, including infective endocarditis. (grantome.com)
  • Aggregatibacter actinomycetemcomitans, a potent pathogen of periodontitis, typically grows as a rough and adherent colony on primary isolated cultures. (elsevier.com)
  • One of the heat shock family protein Hsp expressing bacteria is the gram negative, periodontal pathogen Aggregatibacter actinomycetemcomitans Aa. (duhnnae.com)
  • Aggregatibacter actinimycetemcomitans is an important pathogen related to aggressively progressive periodontal breakdown in adolescents and adults [4,5]. (crimsonpublishers.com)
  • Aggregatibacter actinomycetemcomitans is a Gram-negative opportunistic pathogen and the proposed causative agent of localized aggressive periodontitis. (utexas.edu)
  • Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans) is a Gram-negative, facultative anaerobe, nonmotile bacterium that is often found in association with localized aggressive periodontitis, a severe infection of the periodontium. (wikipedia.org)
  • Aggregatibacter actinomycetemcomitans ( Aa ) is a gram-negative coccobacillus, facultative anaerobe, closely associated with the aetiology of severe periodontitis, but it is also implicated in different human systemic diseases, such as infective endocarditis and, rarely, in brain abscesses, osteomyelitis, or low birth weight [ 1 - 4 ]. (hindawi.com)
  • Aggregatibacter actinomycetemcomitans is a Gram-negative organism, strongly associated with aggressive forms of periodontitis. (diva-portal.org)
  • Åberg CH, Kelk P, Johansson A. Aggregatibacter actinomycetemcomitans: virulence of its leukotoxin and association with aggressive periodontitis. (981heritage.com)
  • Keywords: aggregatibacter actinomycetemcomitans, aggressive periodontitis, bone resorption, infection, inflammation, IL-1b, leukotoxin Periodontitis is an infection-induced inflammatory disease that causes loss of the tooth supporting tissues. (981heritage.com)
  • Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) is a Gram-negative, facultative anaerobic bacillus that causes periodontal diseases such as localized aggressive periodontitis (LAP) and. (981heritage.com)
  • Aggregatibacter actinomycetemcomitans is considered to be a key periodontopathogen and has been associated with aggressive periodontitis (Tonetti and Mombelli, 1999). (dentisty.org)
  • 4. Haubek D. The highly leukotoxic JP2 clone of Aggregatibacter actinomycetemcomitans: evolutionary aspects, epidemiology and etiological role in aggressive periodontitis. (cmac-journal.ru)
  • Genetic Profiling of Aggregatibacter actinomycetemcomitans Serotype B Isolated from Periodontitis Patients Living in Sweden. (nih.gov)
  • The objective of this study was to determine whether the detection of Aggregatibacter actinomycetemcomitans (Aa) correlates with the clinical and immunoinflammatory profile of Localized Aggressive Periodontitis (LAP), as determined by by 16S rRNA gene-based microarray. (wellesley.edu)
  • Kataria S, Chandrashekar K.T, Mishra R, Tripathi V, Galav A and Sthapak U. Effect of tetracycline HCL (periodontal plus AB) on Aggregatibacter actinomycetemcomitans levels in chronic periodontitis . (hoajonline.com)
  • In each patient, periodontal pockets were treated with scaling and root planing alone (control site), or treated by scaling and root planing followed by placement of tetracycline fiber (test site), with the aim of evaluating Aggregatibacter actinomycetemcomitans in chronic periodontitis. (hoajonline.com)
  • Antecedentes La investigación de la microflora subgingival en pacientes diabéticos tipo 2 con periodontitis ha presentado resultados contradictorios. (bvsalud.org)
  • History em Aggregatibacter actinomycetemcomitans /em [1] can be a little Gram-negative pole implicated in intense types of periodontitis [2]. (complextraitgenomics.com)
  • Various studies have associated Aggregatibacter actinomycetemcomitans , formerly known as Actinobacillus actinomycetemcomitans , with aggressive periodontitis. (wikipedia.org)
  • No cualquiera puede presentar los blasones de este medico internista, reumatologo, profesor e investigador de la Universidad Johns Hopkins y lider del equipo de investigadores que identifico la bacteria Aggregatibacter actinomycetemcomitans, presente en la boca y que desencadena la produccion de ciertas proteinas las cuales confunden al sistema inmunologico provocando la afectacion de celulas y tejidos, como las articulaciones. (thefreedictionary.com)
  • These bacteria include Aggregatibacter actinomycetemcomitans, Campylobacter rectus, Desulfovibrio species. (thefreedictionary.com)
  • Aggregatibacter bacteria are a rare cause of endocarditis in adults. (beds.ac.uk)
  • Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* periodontopathogen? (wikipedia.org)
  • Haubek D, Poulsen K, Kilian M. Microevolution and patterns of dissemination of the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans. (atcc.org)
  • 2. Henderson B., Ward J.M., Ready D. Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* periodontopathogen? (cmac-journal.ru)
  • CHARACTERISTICS: Actinobacillus and Aggregatibacter spp. (msdsonline.com)
  • HOST RANGE: Actinobacillus and Aggregatibacter spp. (msdsonline.com)
  • Actinobacillus or Aggregatibacter spp. (msdsonline.com)
  • DRUG SUSCEPTIBILITY/RESISTANCE: Actinobacillus or Aggregatibacter strains are generally susceptible to a range of antibiotics, including cephalosporins, cefotaxime, cefazolin, doxycycline and aminoglycosides (1, 3). (msdsonline.com)
  • After that, the surface of dental implants was inoculated with Aggregatibacter actinomycetemcomitans (A.a.) strains for 4 days and prepared for SEM analysis to determine the percentage area of contamination in a software for image analysis. (usp.br)
  • Our aims were to determine the frequency of ChoP display among Aggregatibacter actinomycetemcomitans strains, to clarify which surface structures bear ChoP, and whether ChoP-positivity relates to serum killing. (diva-portal.org)
  • Differential Cell Lysis Among Periodontal Strains of JP2 and Non-JP2 Genotype of Aggregatibacter actinomycetemcomitans Serotype B Is Not Reflected in Dissimilar Expression and Production of Leukotoxin. (nih.gov)
  • Comprehensive antimicrobial susceptibility testing of a large collection of clinical strains of Aggregatibacter actinomycetemcomitans does not identify resistance to amoxicillin. (nih.gov)
  • The cagE gene sequence as a diagnostic marker to identify JP2 and non-JP2 highly leukotoxic Aggregatibacter actinomycetemcomitans serotype b strains. (scilifelab.se)
  • 8. Kachlany S.C. Aggregatibacter actinomycetemcomitans leukotoxin: from threat to therapy. (cmac-journal.ru)
  • Virulence properties of Aggregatibacter actinomycetemcomitans biofilm and characterisation of its putative cytokine exploitation. (thefreedictionary.com)
  • caseolyticus 9 HIBPF19140 Previously identified in HaeBPF HIBPF20030 Aggregatibacter aphrophilus * Putative product based on closest homologue in public databases, shown by percent amino acid identity. (thefreedictionary.com)
  • Genome sequence of Aggregatibacter actinomycetemcomitans serotype c strain D11S-1. (genome.jp)
  • A bacteriophage specific for Aggregatibacter actinomycetemcomitans serotype b, able to kill the bacterium within a biofilm, was isolated. (unab.cl)
  • Aggregatibacter actinomycetemcomitans is commonly found in Asian populations and several studies showed a clear predominance of serotype c in Japanese, Chinese, Vietnamese, and Korean individuals (6). (msdsonline.com)
  • Aggregatibacter actinomycetemcomitans serotype b str. (expasy.org)
  • Avaliação qualitativa, quantitativa e genotípica de Aggregatibacter actinomycetemcomitans e Fusobacterium nucleatum isolados de pacientes com diferentes condições clínicas bucais. (usp.br)
  • Aggregatibacter actinomycetemcomitans e Fusobacterium nucleatum são microrganismos gram-negativos presentes nos processos inflamatórios e nas diferentes formas da doença periodontal. (usp.br)
  • Qualitative, quantitative and genotypic evaluation of Aggregatibacter actinomycetemcomitans and Fusobacterium nucleatum isolated from patients with diferent oral clinical conditions. (usp.br)
  • Aggregatibacter actinomycetemcomitans and Fusobacterium nucleatum are gram-negative microorganisms observed in inflammatory processes and different forms of periodontal disease. (usp.br)
  • aggregatibacter, rod-shaped bacterium that aggregates with others) was added to the family pasteurellaceae. (981heritage.com)
  • Antibiotic susceptibility of Aggregatibacter actinomycetemcomitans JP2 in a biofilm. (harvard.edu)
  • This study aimed to compare the effect of Curcuma xanthrorrhiza ethanol extract to the viability of Streptococcus mutans and Aggregatibacter actinomycetemcomitans using single- and dual-species biofilm at different phases of formation. (innovareacademics.in)
  • Her antibiotics were changed to ceftriaxone alone once the blood cultures resulted as positive for Aggregatibacter aphrophilus (Figure 2), a HACEK organism. (thefreedictionary.com)
  • В настоящее время бактерии группы HACEK являются возбудителями в 3% случаев инфекционного эндокардита, при этом наиболее частым из них является Aggregatibacter actinomycetemcomitans . (cmac-journal.ru)
  • Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans . (nih.gov)
  • Pacemaker endocarditis caused by Aggregatibacter species is rarely described. (beds.ac.uk)
  • Immortalized human gingival epithelial cells were co-cultured with Aggregatibacter actinomycetemcomitans Y4 (Aa Y4), and the gene expression levels of IL-8, proliferating cell nuclear antigen (PCNA), and integrins (α2, α3, α5, β4, and β6) were measured using quantitative reverse transcription polymerase chain reaction. (elsevier.com)
  • In this study, we investigated the effects of omega-3 fatty acids on inflammatory responses and cell death induced by the Gram-negative bacterium Aggregatibacter actinomycetemcomitans in macrophages. (alliedacademies.org)
  • Yet, oddly, these virulence factors are fairly rare among oral pathogens, with one exception, the Gram-negative Aggregatibacter actinomycetemcomitans . (asmblog.org)
  • 2000) have categorised the virulence factors of Aggregatibacter actinomycetemcomitans as follows. (wikipedia.org)
  • Samaranayake notes the evidence for the specific involvement of Aggregatibacter actinomycetemcomitans includes: an increased incidence of it found in subgingival plaque obtained from lesional sites, high level of its antibody which tends to fall following successful treatment, its possession of a wide range of potentially pathogenic products and its elimination with concordant disease regression, following treatment with successful periodontal therapy and adjunctive tetracycline . (wikipedia.org)
  • Aggregatibacter actinomycetemcomitans is a Gram-negative microorganism that is frequently isolated from patients with periodontal disease [ 1 ]. (alliedacademies.org)
  • Effects of the Aggregatibacter actinomycetemcomitans is associated with periodontal disease has been given in recent. (981heritage.com)
  • Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium associated with periodontal disease and a variety of disseminated extra-oral infections. (grantome.com)
  • Liver and brain abscess caused by Aggregatibacter paraphrophilus in association with a large patent foramen ovale: a case report. (ox.ac.uk)
  • CASE PRESENTATION: We report a case of a 53-year-old Caucasian man with a liver abscess and subsequent brain abscesses caused by Aggregatibacter paraphrophilus. (ox.ac.uk)
  • CONCLUSION: In this case report, we describe an unusual case of a patient with both liver and brain abscesses caused by an oral commensal Aggregatibacter paraphrophilus that can occasionally show significant pathogenic potential. (ox.ac.uk)
  • We present a case of pacemaker endocarditis secondary to Aggregatibacter aphrophilus , an organism not previously described in the literature as causing pacemaker endocarditis. (beds.ac.uk)
  • Binding of Aggregatibacter actinomycetemcomitans to collagen fibers of heart valves. (uvm.edu)
  • The present study reports on a fatal case of a previously well 42-year-old alcoholic woman with infective endocarditis caused by Aggregatibacter aphrophilus, with secondary brain abscess and spontaneous rupture into the ventricles causing PV. (hindawi.com)
  • Very few cases of Aggregatibacter endocarditis in patients with pacemaker devices have been reported. (beds.ac.uk)
  • We present here what we believe to be the first case of Aggregatibacter aphrophilus pacemaker endocarditis. (beds.ac.uk)
  • Read More Aggregatibacter actinomycetemcomitans: A Healthy Mouth or Systemic Infection? (thermofisher.com)
  • In this regard, most Cdts, including the Aggregatibacter actinomycetemcomitans Cdt are heterotrimeric holotoxins that function as AB 2 toxins. (frontiersin.org)
  • Oral lactobacilli reduce cytotoxicity and cytokine release from peripheral blood mononuclear cells exposed to Aggregatibacter actinomycetemcomitans subtypes in vitro. (researchsquare.com)
  • Background: This study evaluated the effect of oral lactobacilli on the cytotoxicity and cytokine release from peripheral blood mononuclear cells (PBMC) when exposed to Aggregatibacter actinomycetemcomitans subtypes in vitro. (researchsquare.com)
  • En el grupo de pacientes diabéticos estudiado, las bacterias más prevalentes fueron Treponema denticola y Tannerella forsythia . (bvsalud.org)
  • 41) used polymerase chain reaction to reveal a significantly higher prevalence of Actinomyces and Aggregatibacter actinomycetemcomitans in black stain compared to the plaque of the control group. (thefreedictionary.com)
  • The present study investigated the effects of highbush blueberry proanthocyanidins (PACs) on the virulence properties of Aggregatibacter actinomycetemcomitans and macrophage-associated inflammatory responses. (biomedcentral.com)