Aggregatibacter actinomycetemcomitans: A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to dental surfaces. It is associated with PERIODONTITIS; BACTERIAL ENDOCARDITIS; and ACTINOMYCOSIS.Pasteurellaceae: A family of coccoid to rod-shaped nonsporeforming, gram-negative, nonmotile, facultatively anaerobic bacteria that includes the genera ACTINOBACILLUS; HAEMOPHILUS; MANNHEIMIA; and PASTEURELLA.Pasteurellaceae Infections: Infections with bacteria of the family PASTEURELLACEAE.Actinobacillus Infections: Infections with bacteria of the genus ACTINOBACILLUS.Aggressive Periodontitis: Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.Aggregatibacter segnis: A species of Gram-negative, facultatively anaerobic pleomorphic rod-shaped often filamentous bacteria in the genus of AGGREGATIBACTER found in the oral cavity. It is associated with DENTAL PLAQUE; and BACTERIAL ENDOCARDITIS.Aggregatibacter aphrophilus: A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to oral cavity and pharynx. It is associated with BACTERIAL ENDOCARDITIS; and MENINGITIS.Exotoxins: Toxins produced, especially by bacterial or fungal cells, and released into the culture medium or environment.Aggregatibacter: A genus of PASTEURELLACEAE. Members are nonmotile, Gram-negative, facultatively anaerobic rods or coccobacilli. Its members are X factor (HEMIN) independent and variably dependent on V factor (NAD).Gingiva: Oral tissue surrounding and attached to TEETH.Chronic Periodontitis: Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.Campylobacter rectus: A species of CAMPYLOBACTER isolated from cases of human PERIODONTITIS. It is a microaerophile, capable of respiring with OXYGEN.Periodontal Pocket: An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.Periodontal Diseases: Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Gingival Hemorrhage: The flowing of blood from the marginal gingival area, particularly the sulcus, seen in such conditions as GINGIVITIS, marginal PERIODONTITIS, injury, and ASCORBIC ACID DEFICIENCY.Treponema denticola: A species of bacteria in the family SPIROCHAETACEAE, frequently isolated from periodontal pockets (PERIODONTAL POCKET).Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)Dental Plaque: A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.Prevotella intermedia: A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium is a common commensal in the gingival crevice and is often isolated from cases of gingivitis and other purulent lesions related to the mouth.Fusobacterium nucleatum: A species of gram-negative, anaerobic, rod-shaped bacteria isolated from the gingival margin and sulcus and from infections of the upper respiratory tract and pleural cavity.Porphyromonas gingivalis: A species of gram-negative, anaerobic, rod-shaped bacteria originally classified within the BACTEROIDES genus. This bacterium produces a cell-bound, oxygen-sensitive collagenase and is isolated from the human mouth.Dental Devices, Home Care: Devices used in the home by persons to maintain dental and periodontal health. The devices include toothbrushes, dental flosses, water irrigators, gingival stimulators, etc.Actinobacillus: A genus of PASTEURELLACEAE described as gram-negative, nonsporeforming, nonmotile, facultative anaerobes. Most members are found both as pathogens and commensal organisms in the respiratory, alimentary, and genital tracts of animals.Bacterial Load: Measurable quantity of bacteria in an object, organism, or organism compartment.Cardiobacterium: A genus of gram-negative, facultatively anaerobic bacteria in the family CARDIOBACTERIACEAE. It is found in the nasal flora of humans and causes ENDOCARDITIS.Biofilms: Encrustations, formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedding in extracellular polymers, that adhere to surfaces such as teeth (DENTAL DEPOSITS); PROSTHESES AND IMPLANTS; and catheters. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and antifouling agents.Peri-Implantitis: An inflammatory process with loss of supporting bone in the tissues surrounding functioning DENTAL IMPLANTS.Periodontium: The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.Alveolar Bone Loss: Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.Gingivitis: Inflammation of gum tissue (GINGIVA) without loss of connective tissue.Streptococcus gordonii: A species of gram-positive, facultatively anaerobic bacteria in the family STREPTOCOCCACEAE. It is a normal inhabitant of the human oral cavity, and causes DENTAL PLAQUE and ENDOCARDITIS. It is being investigated as a vehicle for vaccine delivery.Dental Plaque Index: An index which scores the degree of dental plaque accumulation.Haemophilus somnus: A species of gram-negative bacteria (currently incertae sedis) causing multisystem disease in CATTLE.Periodontal Index: A numerical rating scale for classifying the periodontal status of a person or population with a single figure which takes into consideration prevalence as well as severity of the condition. It is based upon probe measurement of periodontal pockets and on gingival tissue status.Adhesins, Bacterial: Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.Bacterial Toxins: Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.Haemophilus: A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.Periodontal Attachment Loss: Loss or destruction of periodontal tissue caused by periodontitis or other destructive periodontal diseases or by injury during instrumentation. Attachment refers to the periodontal ligament which attaches to the alveolar bone. It has been hypothesized that treatment of the underlying periodontal disease and the seeding of periodontal ligament cells enable the creating of new attachment.Gingival Crevicular Fluid: A fluid occurring in minute amounts in the gingival crevice, believed by some authorities to be an inflammatory exudate and by others to cleanse material from the crevice, containing sticky plasma proteins which improve adhesions of the epithelial attachment, have antimicrobial properties, and exert antibody activity. (From Jablonski, Illustrated Dictionary of Dentistry, 1982)Mouth: The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.Bacterial Adhesion: Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.Bacterial Proteins: Proteins found in any species of bacterium.Gene Expression Regulation, Bacterial: Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.Nicotinamide Phosphoribosyltransferase: An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).Bacteroides: A genus of gram-negative, anaerobic, rod-shaped bacteria. Its organisms are normal inhabitants of the oral, respiratory, intestinal, and urogenital cavities of humans, animals, and insects. Some species may be pathogenic.Virulence Factors: Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)Gram-Negative Bacteria: Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Genome, Bacterial: The genetic complement of a BACTERIA as represented in its DNA.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Epithelial Cells: Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

Phenotypic variation in Actinobacillus actinomycetemcomitans during laboratory growth: implications for virulence. (1/6)

This study examined alteration of specific virulence traits associated with phenotypic changes seen when a low-passage disease-associated and well maintained parent strain of Actinobacillus actinomycetemcomitans was compared to a laboratory-grown spontaneous variant/mutant. Clinical isolates of A. actinomycetemcomitans recovered from periodontitis patients typically grow as rough, adherent colonies on primary culture but undergo transformation to smooth, non-adherent colonies following repeated passage in vitro. The relationship of these phenotypic changes to the virulence of the organism or to the processes that underlie this transformation are not understood. A fresh clinical isolate, designated strain CU1000, was obtained from the first molar site of a patient with classical signs of localized juvenile periodontitis and used as the parent strain to study virulence-related phenotypes. Following several passages of CU1000 on selective agar, a spontaneous variant that demonstrated smooth, opaque, non-adherent colonies was isolated and designated strain CU1060. This study compared the properties of these two strains with respect to colony morphology, autoaggregation, surface appendages, adherence to saliva-coated hydroxyapatite (SHA), LPS chemotype and activity, induction of fibroblast proteinase activity and antigenic properties. CU1000 demonstrated rough, raised, star-positive colonies which upon electron microscopic examination revealed the presence of large, flexible, bundled fibrils. In addition, CU1000 showed adherence to SHA, several unique protein antigens and elevated endotoxin and fibroblast proteinase activity. CU1060, on the other hand, showed minimal adherence to SHA and fewer reactive proteins compared to the fresh clinical isolates. This strain formed smooth, opaque colonies on agar, showed minimal fibril formation and limited endotoxin and fibroblast-proteinase-inducing activity. These findings demonstrate that clinical isolates of A. actinomycetemcomitans undergo significant virulence-reducing phenotypic alterations during in vitro passage and support the need to study this organism in its clinical form.  (+info)

Structural and genetic analyses of O polysaccharide from Actinobacillus actinomycetemcomitans serotype f. (2/6)

The oral bacterium Actinobacillus actinomycetemcomitans is implicated as a causative agent of localized juvenile periodontitis (LJP). A. actinomycetemcomitans is classified into five serotypes (a to e) corresponding to five structurally and antigenically distinct O polysaccharide (O-PS) components of their respective lipopolysaccharide molecules. Serotype b has been reported to be the dominant serotype isolated from LJP patients. We determined the lipopolysaccharide O-PS structure from A. actinomycetemcomitans CU1000, a strain isolated from a 13-year-old African-American female with LJP which had previously been classified as serotype b. The O-PS of strain CU1000 consisted of a trisaccharide repeating unit composed of L-rhamnose and 2-acetamido-2-deoxy-D-galactose (molar ratio, 2:1) with the structure -->2)-alpha-L-Rhap-(1-3)-2-O-(beta-D-GalpNAc)-alpha-L-Rhap-(1-->* O-PS from strain CU1000 was structurally and antigenically distinct from the O-PS molecules of the five known A. actinomycetemcomitans serotypes. Strain CU1000 was mutagenized with transposon IS903phikan, and three mutants that were deficient in O-PS synthesis were isolated. All three transposon insertions mapped to a single 1-kb region on the chromosome. The DNA sequence of a 13.1-kb region surrounding these transposon insertions contained a cluster of 14 open reading frames that was homologous to gene clusters responsible for the synthesis of A. actinomycetemcomitans serotype b, c, and e O-PS antigens. The CU1000 gene cluster contained two genes that were not present in serotype-specific O-PS antigen clusters of the other five known A. actinomycetemcomitans serotypes. These data indicate that strain CU1000 should be assigned to a new A. actinomycetemcomitans serotype, designated serotype f. A PCR assay using serotype-specific PCR primers showed that 3 out of 20 LJP patients surveyed (15%) harbored A. actinomycetemcomitans strains carrying the serotype f gene cluster. The finding of an A. actinomycetemcomitans serotype showing serological cross-reactivity with anti-serotype b-specific antiserum suggests that a reevaluation of strains previously classified as serotype b may be warranted.  (+info)

Tight-adherence genes of Actinobacillus actinomycetemcomitans are required for virulence in a rat model. (3/6)

Actinobacillus actinomycetemcomitans is a Gram-negative coccobacillus that has been associated with localized aggressive periodontitis and infections of the heart, brain, and urinary tract. Wild-type clinical isolates have the remarkable ability to adhere tenaciously and nonspecifically to solid surfaces such as glass, plastic, and hydroxyapatite. Adherence by A. actinomycetemcomitans is mediated by the tight-adherence (tad) gene locus, which consists of 14 genes (flp-1-flp-2-tadV-rcpCAB-tadZABCDEFG). All but 2 of the genes have been shown to be required for the secretion and assembly of long, bundled Flp1 fibrils. To test whether the tad locus is required for colonization and disease, we developed a rat model for periodontal disease. To mimic the natural route of infection, Sprague-Dawley rats were inoculated orally by adding bacteria directly to their food for 8 days. After inoculation with wild-type or mutant strains defective in adherence (flp-1 and tadA), the rats were assessed for colonization of the oral cavity and pathogenesis. Wild-type A. actinomycetemcomitans was able to colonize and persist for at least 12 weeks in the oral cavity, elicit a humoral immune response, and cause significant bone loss in rats. In contrast, rats fed flp-1 or tadA mutant strains showed no bone loss and their immune responses were indistinguishable from those of the uninoculated controls. These results demonstrate the critical importance of the tad locus in the colonization and pathogenesis of A. actinomycetemcomitans.  (+info)

Novel surface structures are associated with the adhesion of Actinobacillus actinomycetemcomitans to collagen. (4/6)

Actinobacillus actinomycetemcomitans is a gram-negative, facultative, anaerobic bacterium that colonizes the human oral cavity and the upper respiratory tract. This bacterium is strongly associated with localized aggressive periodontitis and adult periodontitis and is the causative agent for other serious systemic infections. Recently, we have identified a protein, EmaA (extracellular matrix protein adhesin A), that mediates the adhesion of A. actinomycetemcomitans to collagen. The conserved sequence and predicted secondary structure suggest that EmaA is an orthologue of the Yersinia enterocolitica adhesin YadA. Electron microscopy examinations of A. actinomycetemcomitans have identified antenna-like protrusions associated with the surface of the bacterium. These structures are absent on emaA mutant strains and can be restored by transformation of the mutant strain with emaA in trans. The loss of these structures is associated with a decrease in the binding of this bacterium to collagen. The antenna-like structures are composed of a long rod that terminates in an ellipsoidal head region. The analysis of these structures using image processing techniques has provided an initial estimate of the overall dimensions, which suggests that the appendages are oligomeric structures formed by either three or four subunits. Together, the data suggest that emaA is required for the expression of novel appendages on the surface of A. actinomycetemcomitans that mediate the adhesion of the bacterium to collagen.  (+info)

HACEK infective endocarditis: characteristics and outcomes from a large, multi-national cohort. (5/6)

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Epithelial cell invasion by Actinobacillus actinomycetemcomitans strains from restriction fragment-length polymorphism groups associated with juvenile periodontitis or carrier status. (6/6)

The epithelial cell invasiveness of Actinobacillus actinomycetemcomitans strains of different restriction fragment-length polymorphism (RFLP) groups associated with disease conversion and asymptomatic carrier status in localized juvenile periodontitis was examined. Twenty clinical isolates were studied for their ability to invade KB monolayers, using the quantitative gentamicin killing assay. Five isolates were found to be invasive, five were not invasive; and the other 10 did not invade better than an invasion negative control Haemophilus aphrophilus strain ATCC 19415. Using probe-specific DNA fingerprinting. 11 strains were assigned to RFLP group II (disease-associated); 4 to RFLP type XIII (carrier status associated); and the other to groups III, IV, V and VII. Eight isolates, all RFLP group II, were leukotoxin producers as determined by PCR amplification of the lkt promoter region. No correlation was found between invasiveness and RFLP group. Leukotoxin production was more associated with noninvasive than invasive strains.  (+info)

*Pasteurellaceae

CSIs have also been found that are specific for Aggregatibacter and Mannheimia , two clinically relevant genera. The ... Other pathogenic members belonging to the Pasteurellaceae family include Aggregatibacter, Mannheimia, Pasteurella, and ... One proposed clade includes Aggregatibacter, Pasteurella, Actinobacillus succinogenes, Haemophilus influenzae, Haemophilus ...

*Aggregatibacter

Nov., Aggregatibacter aphrophilus comb. Nov. And Aggregatibacter segnis comb. Nov., and emended description of Aggregatibacter ... Nov., Aggregatibacter aphrophilus comb. Nov. And Aggregatibacter segnis comb. Nov., and emended description of Aggregatibacter ... Nov., Aggregatibacter aphrophilus comb. Nov. And Aggregatibacter segnis comb. Nov., and emended description of Aggregatibacter ... Aggregatibacter is a genus in the phylum Proteobacteria (Bacteria), which contains three species, namely: A. ...

*Aggregatibacter actinomycetemcomitans

nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Type strain of Aggregatibacter actinomycetemcomitans at BacDive - the Bacterial Diversity Metadatabase. ... Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans) is a Gram-negative, facultative ... suggesting the new genus Aggregatibacter for them. It is one of the bacteria that might be implicated in destructive ...

*Aggregatibacter iron-regulated sRNA

... sequence were identified by bioinformatics analysis in Aggregatibacter actinomycetemcomitans HK1651 called JA01-JA04. The ... "Novel iron-regulated and Fur-regulated small regulatory RNAs in Aggregatibacter actinomycetemcomitans". Molecular Oral ...

*Index of oral health and dental articles

Aggregatibacter actinomycetemcomitans • Aim toothpaste • Akers' clasp • Alberta Dental Association and College • Alfred Fones ...

*Capnophile

Other capnophilic pathogens occur in the Gram-negative Aggregatibacter spp. found in the mouth (e.g. Aggregatibacter ... "Sensitivity of the periodontal pathogen Aggregatibacter actinomycetemcomitans at mildly acidic pH". J Periodontol. 82 (6): 917- ...

*Actinobacillus

nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Aggregatibacter (from the Latin, "aggregare", meaning "to come together"). Chung; et al. (2008). "Actinobacillus ... and clinical significance of haemophilus and aggregatibacter species with host specificity for humans". Clinical Microbiology ... Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. ...

*Epoxygenase

Aggregatibacter actinomycetemcomitans and E. coli. That is, they are toxic to leukocytes as well as many other cell types and ...

*PrrF RNA

HrrF RNA NrrF RNA Aggregatibacter iron-regulated sRNA Wilderman, PJ; Sowa NA; FitzGerald DJ; FitzGerald PC; Gottesman S; ...

*HrrF RNA

Iron- regulated sRNAs JA01- JA04 were identified in related Aggregatibacter. It is an analog to PrrF and RyhB RNAs. HrrF is ...

*Aggressive periodontitis

As well as Aggregatibacter actinomycetemcomitans being associated with this, the synergism of the disease also accounts for ... High levels of Aggregatibacter (or Actinobacillus) actinomycetemcomitans and, in some populations, Porphyromonas gingivalis. ... This is due to the suppression of serum IgG2 and antibody against Aggregatibacter actinomycetemcomitans found in smokers. ... A significant reduction in the aggregatibacter actinomycetemcomitans count following PDT suggests that the use of PDT in ...

*Coccobacillus

Aggregatibacter actinomycetemcomitans is a Gram-negative coccobacillus prevalent in subgingival plaques. Acinetobacter strains ...

*Actinomyces

Aggregatibacter actinomycetemcomitans has been identified as being of note in periodontal disease. The genus is typically the ...

*Bacterial cellular morphologies

Aggregatibacter actinomycetemcomitans is a gram negative coccobacillus which is prevalent in subgingival plaques. Acinetobacter ...

*HACEK organisms

Aggregatibacter segnis Aggregatibacter aphrophilus (previously Haemophilus aphrophilus) Aggregatibacter paraphrophilus ( ... Haemophilus haemolyticus Haemophilus parahaemolyticus Aggregatibacter Aggregatibacter actinomycetemcomitans (previously ... However, taxonomic rearrangements have changed the A to Aggregatibacter species and the H to Haemophilus species to reflect the ... HACEK is an abbreviation of the initials of the genera of this group of bacteria: Haemophilus, Aggregatibacter (previously ...

*Dam methylase

The retainment of viability despite a dam gene knockout is also seen in Salmonella and Aggregatibacter actinomycetemcomitans. ... A knockout of the dam gene in Aggregatibacter actinomycetemcomitans resulted in dysregulated levels of the protein, leukotoxin ...

*Haemophilus aphrophilus

... was a species of Haemophilus but the name has recently been changed to Aggregatibacter aphrophilus. It ...

*NrrF RNA

RhyB RNA PrrF RNA HrrF RNA Aggregatibacter iron-regulated sRNA Neisseria sigma-E sRNA Neisseria RNA thermometers Mellin, J. R ...

*Jørgen Slots

Slots is responsible for discovering the role of Aggregatibacter actinomycetemcomitans (previously Actinobacillus ...

*Dispersin B

... is produced by Aggregatibacter actinomycetemcomitans, a Gram-negative oral bacterium, when it needs to detach and ... Aggregatibacter actinomycetemcomitans. The bacteria secrete Dispersin B to release adherent cells from a mature biofilm colony ...

*Tryptic soy-serum-bacitracin-vancomycin

... a type of agar plate medium used in microbiological testing to select for Aggregatibacter actinomycetemcomitans (A.a.). It was ...

*Conserved signature indels

Two major clades are formed within this Pasteurellales: Clade I, encompassing Aggregatibacter, Pasteurella, Actinobacillus ...

*List of bacterial vaginosis microbiota

Actinobacteria spp Anaerococcus spp Actinomyces naeslundii Aggregatibacter actinomycetemcomitans Atopobium vaginae Bacteroides ...

*Maresin

Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans; the latter functional defects were improved by treating the ...

*Cytolethal distending toxin

Medically important CDT producers include: Haemophilus ducreyi (chancroids) Aggregatibacter actinomycetemcomitans ( ...
BACKGROUND: Socio-economic inequalities in mortality are observed at the country level in both North America and Europe. The purpose of this work is to investigate the contribution of specific risk factors to social inequalities in cause-specific mortality using a large multi-country cohort of Europeans. METHODS: A total of 3,456,689 person/years follow-up of the European Prospective Investigation into Cancer and Nutrition (EPIC) was analysed. Educational level of subjects coming from 9 European countries was recorded as proxy for socio-economic status (SES). Cox proportional hazard models with a step-wise inclusion of explanatory variables were used to explore the association between SES and mortality; a Relative Index of Inequality (RII) was calculated as measure of relative inequality. RESULTS: Total mortality among men with the highest education level is reduced by 43% compared to men with the lowest (HR 0.57, 95% C.I. 0.52-0.61); among women by 29% (HR 0.71, 95% C.I. 0.64-0.78). The risk ...
Findings from the Prospective Urban Rural Epidemiology (PURE) Study-which consisted of more than 135,000 individuals from 18 low-, middle- and high-income countries from five continents-showed that (1) high carbohydrate intake was linked to worse total mortality, whereas high fat intake was linked to lower risk; (2) reducing saturated fat intake and replacing it with carbohydrate was linked to the most adverse effects on blood lipids; and (3) combined fruit, vegetable, and legume consumption at 3-4 servings per day were associated with a lower total mortality and non-cardiovascular mortality [1-3].. One of the most consistent dietary guidelines in the Western Hemisphere is to restrict saturated fat intake to less than 10% of total calories per day and replace saturated fat (e.g., animal fats) with unsaturated fat (e.g., vegetable oils) and complex carbohydrates [4]. However, a growing number of scientists are questioning this recommendation as more studies have demonstrated the lack of an ...
BACKGROUND: MiRNA-binding-site single nucleotide polymorphisms (SNPs) in homologous recombination repair (HRR) pathway genes may change DNA repair capacity and affect susceptibility to cancer. However, these SNPs associated with breast cancer (BC) are still unclear in Chinese women.. METHODS: We performed a case-control study of 450 BC patients and 450 matched cancer-free controls in Chinese Han women. Five miRNA-binding-site SNPs in HRR pathway genes (MRE11A rs2155209, NBS1 rs2735383, RAD51 rs963917 and rs963918 and RAD52 rs7963551) were genotyped by the restriction fragment-length polymorphism (PCR-RFLP) method; a chi-square (χ2) test was used to compare the differences in the genotypic distribution between the BC cases and controls. The interactions of gene-gene and gene-reproduction factors were computed by logistic regression models.. RESULTS: Gene-gene and gene-reproduction factors interaction analysis among HRR pathway genes showed significant effects on BC risk. the individuals with TC ...
After immunoflurescent microscopy DNA mutational analysis is the final step in elucidating the underlying molecular defect, and in most cases, it reduces the number of genes to be screened. DNA is extracted from blood of the patient and family members. Initial mutation screening is performed by restriction fragment-length polymorphism analysis, hotspot analysis, and finally, direct DNA sequencing ...
In 2013, the Organisation for Economic Cooperation and Development (OECD) announced its Action Plan on Base Erosion and Profit Shifting…
MTI wanted to refresh its communications infrastructure to encourage mobile working and a paperless environment. To do so, it needed to find a way to improve call extension efficiency using smartphones.
The European Womens Championship, which kicks off in Blackpool, is the biggest multi-national football event in Britain since Euro 96.
Brochures from Paradigm®, the worlds largest multi-national software company focused on analytical and information management solutions for oil and gas resources
These kitting trays feature static dissipative foam that allows for safe transport of PCB and SMT components. We are a multi-national distributor of static control products for the electronics and medical device manufacturing industries.
Cargill is a multi-national corporation who, like any other corporation, is interested in profits. If they can gain some profit from organics, they will just as they will gain profits from agri-business and gmo crops. This doesnt mean they are concerned with soil health or with the environment or with feeding the world. Their motivation is profit. If there is something to be had from sourcing organic cacoa from Africa ..... they will be there doing just that. Of course, there has been a lot of pressure for Cargill to source their cacoa from outfits that are not using child-slavery .....and they are now doing that .... but the initiative to do so did not come from them. They had to be made aware from groups whose main focus was not profit, but accountability and equality ...
Regardless of how you feel about how multi-national conglomerates have changed healthcare IT, you must at least acknowledge GE Healthcares size and influence.
Coupled with heliums attributes, which are impossible to replicate, and numerous new applications for helium currently being evaluated, heliums status as a highly strategic and valuable commodity is clearly established.. Helium is currently produced as a by-product of natural gas processing and LNG production, with global supply concentrated among six large multi-national companies. In contrast to most of the existing helium production facilities, Helium Ones assets are standalone helium projects that have the potential to materially enhance global helium reserves.. ...
McLibel is an extraordinary tale of how two ordinary people, gardener Helen Steel and postman Dave Morris stood against the multi-national giant, McDonal...
Mr. Katzenberg landed flat on his back after Michael Eisner threw him out of Walts Kingdom. But he picked himself up and built an enterprise that has generated not only a lot of entertaining features, but provided lots of work for a lot of animation artists. Hes performed a corporate high-wire act for nearly twenty years, something that even Pixar -- now a division of a huge multi-national conglomerate -- failed to achieve. And the fact that Jeffrey hasnt sold DreamWorks Animation to one of the other entertainment conglomerates says more about our current economy than it does about him. (Pixar was purchased by the Disney Company for a premium price years before the 2008 financial meltdown. If the timing had been different, it quite possibly would have remained a stand-alone animation studio in the same way that DWA is today ... or made Mr. Jobs and his heirs a lot less money at the point of purchase ...
NORWOOD, MA--(Marketwired - January 29, 2018) - Multi-national Phase 2b is designed to provide clear evidence of clinical benefit of lenabasum (formerly known as anabasum) in patients with CFStudy will enroll ~415 participants with CF 12 years of age and older regardless of underlying CFTR mutation, infection, or background medicationsFirst...
Now, patience over the alien situation has run out. Control over the aliens has been given to Multi-National United (MNU), a private South African company uninterested in the aliens welfare and only in the weapons they bring and the millions they stand to make from obtaining them. Since activation of the weaponry requires alien DNA, MNU has failed in this and tension between the aliens and the humans reaches a boiling point when an MNU field operative, Wikus van der Merwe (Sharlto Copley), contracts a mysterious virus that begins altering his DNA. Wikus quickly becomes the most hunted man in the world, as well as the most valuable - he is the key to unlocking the secrets of alien technology. Ostracized and friendless, there is only one place left for him to hide: District 9 ...
Benchmark Email is a multi-national email marketing company with offices in Long Beach, CA and Gurgaon, India providing solutions for small businesses and corporations. It also provides technical and marketing support from India to both the US and the World.
What are the typical reasons behind cross-border alliances? What are some of the government influences that impact MNCs (Multi-National.
Genomic sequencing recently reported by two multi-national research teams presents both challenges and opportunities in the battle against malaria.
Shanghai SINCH Pharmaceuticals Tech. Co., Ltd (hereinafter called "SINCH Pharmaceuticals"), is a leading pharmaceutical company specialized in the field of medicine research & development. Since its establishment in the year of 2006, SINCH Pharmaceuticals has been focusing on developing high-quality chemical compound synthesis, herbal and natural medicines for senile and chronic diseases treatment. SINCH Pharmaceuticals possesses a strong R&D team of thirteen dedicated scientists, among which four of them hold PHD degree, while ten of them have education background of BS or above. The company is managed by a group of experts who had abundant working experiences in first-rank multi-national pharmaceutical enterprises. Its location in Wujiaochang High-tech Industry Park, a region in which most renowned universities of Shanghai gathered, allows SINCH Pharmaceuticals to build a stable cooperation relationship in drug research and development with many neighboring chemical institutes. SINCH ...
My Papa was born to a poor family. He lost his father when he was only a kid and never had the chance to finish primary school. Determined to have a better life, he left his hometown in Liloan, Southern Leyte and headed South in the island of Mindanao. He worked as a laborer in various companies until luck smiled down on him and he got hired in a multi-national beverage company in Davao. While we were growing up, my Papa worked very hard just to send all four of us to school. He was the disciplinarian type and when we were smaller, he would discipline us when he can. A very responsible father who wants to provide for his family, I can say that he has really done his best. I am very thankful for everything that he has done for us although I miss the times that he could have been there but he cannot because he has to work. Now, he just retired from work. I hope that he will be able to enjoy his time with my mother, now that all of us are grown-ups and have families of our own too. I miss my Papa. ...
My Papa was born to a poor family. He lost his father when he was only a kid and never had the chance to finish primary school. Determined to have a better life, he left his hometown in Liloan, Southern Leyte and headed South in the island of Mindanao. He worked as a laborer in various companies until luck smiled down on him and he got hired in a multi-national beverage company in Davao. While we were growing up, my Papa worked very hard just to send all four of us to school. He was the disciplinarian type and when we were smaller, he would discipline us when he can. A very responsible father who wants to provide for his family, I can say that he has really done his best. I am very thankful for everything that he has done for us although I miss the times that he could have been there but he cannot because he has to work. Now, he just retired from work. I hope that he will be able to enjoy his time with my mother, now that all of us are grown-ups and have families of our own too. I miss my Papa. ...
My Papa was born to a poor family. He lost his father when he was only a kid and never had the chance to finish primary school. Determined to have a better life, he left his hometown in Liloan, Southern Leyte and headed South in the island of Mindanao. He worked as a laborer in various companies until luck smiled down on him and he got hired in a multi-national beverage company in Davao. While we were growing up, my Papa worked very hard just to send all four of us to school. He was the disciplinarian type and when we were smaller, he would discipline us when he can. A very responsible father who wants to provide for his family, I can say that he has really done his best. I am very thankful for everything that he has done for us although I miss the times that he could have been there but he cannot because he has to work. Now, he just retired from work. I hope that he will be able to enjoy his time with my mother, now that all of us are grown-ups and have families of our own too. I miss my Papa. ...
Mason, OH Aniara Corporation, a multi-national distributor of diagnostic and research agents, as well as screening tools, has strengthened its commitment to meeting today s highest standards for pro...
One of the most concerning business trends today is the increasing number of misleading facts or data that triggers the wrong managerial reaction.. Case in point: a large multi-national company conducts an all-employee survey and reports better-than-expected results even amid a year of layoffs, management changes and competitive pressures. Leadership feels confident in their approach and changes nothing. Within three months, several key executives leave, the union stages a walk- out, the stock plummets and key new product introductions are delayed.. What happened? The results documented in the survey were not accurate. Employees, knowing the future is uncertain if not shaky, chose to answer questions positively fearing for their jobs. Leadership, lacking curiosity and knowing the results went against what they were seeing daily in the workplace ignored reality.. The effect: a major talent drain within six months, delayed programs, and reduced revenue and share targets.. Case in Point: Sales of a ...
More than 25 nationalities are served in this multi-national, multi-ethnic program that provides a variety of services including information and referral to community resources, English as a Second Language (ESL) tutoring, citizenship preparation, health literacy assistance and translation services for those in Bergen, Essex and Morris counties ...
CAMP VICTORY, Iraq - "The doctors said that she would not be able to sustain life on her own after birth," Spc. Clay R. Weaver, Special Troops Battalion, Multi-National Corps-Iraq said. "My wife and I were devastated and they said that they could perform an abortion. That was out of the question. We agreed that we would do anything we could to help Aili fight the odds ...
... LAS VEGAS Feb. 22 2017 /- &nb... When I lost Ron four years ago I knew that his legacy in addition t...Dr. Gilbert 52 was shot and killed by a patient in a tragic case of ... Reckitt Benckiser approached our company in 2014 expressing an inter...,Company,Of,Murdered,California,Urologist,,Absorption,Pharmaceuticals,,Files,Suit,Against,Multi-National,Maker,Of,Everyday,Household,Products,For,Trade,Secret,Theft,And,Fraud,medicine,advanced medical technology,medical laboratory technology,medical device technology,latest medical technology,Health
This is a Randomized, Double-blind, Multi-center, Multi-national Trial to Evaluate the statistical equivalence of efficacy, safety and immunogenicity of SAIT101 Versus Rituximab as a First-line Immunotherapy Treatment in asymptomatic patients with Low Tumor Burden Follicular Lymphoma. Patients will be randomized in a 1:1 ratio to receive study drug once a week for 4 weeks, and will then be followed up for up to 52 weeks after the first dose. Randomization will be stratified by inclusion in the PK/PD sub-population and Follicular lymphoma international prognostic index 2 (FLIPI-2) score.. Visits are scheduled at Weeks 1, 2, 3, and 4 (study drug infusion visits), and then at Weeks 5, 12, 20, 28, 36, and 52 (i.e., End of Study [EOS]). Efficacy response assessments will be performed at Weeks 12 and 28, while safety assessments will continue until EOS.. The primary objectives is To compare the efficacy of SAIT101 with rituximab licensed in the European Union (hereafter designated MabThera®, brand ...
To develop the significance of human inborn errors of membrane function in terms of their potential for the elucidation of physiological processes, an overview of the genetics of inherited metabolic disorders is first presented, concisely covering classical Mendelian inheritance and progressing to molecular applications currently being used in the isolation of a number of disease-causing genes. Second, approaches to the isolation of several genes implicated in inherited disorders of membrane function are discussed. Examples are drawn from studies of the Shaker/IA K+ channel mutants of Drosophila and human inborn errors in the low-density lipoprotein receptor and Kidd antigen/urea transporter. These examples illustrate the techniques of "reverse" genetics, restriction fragment-length polymorphism analysis, chromosomal walking, and cDNA library screening with oligonucleotides and antibodies. Finally, the need to develop a physiological functional analysis of the protein structures derived from ...
The only disclosure restriction on the PI is that the sponsor can review results communications prior to public release and can embargo communications regarding trial results for a period that is more than 60 days but less than or equal to 180 days. The sponsor cannot require changes to the communication and cannot extend the embargo ...
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project "NanoFRET" is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible. ...
Raleigh, NC (PRWEB) June 14, 2010 -- Agile Sciences today announced that a major international chemical company will support the further evaluation of Agile
Monoclonal antibody against Aggregatibacter actinomycetemcomitans serotype b expressed by for use in Western Blot against gram-negative bacteria
In absence of patient-level databases, multi-national, retrospective chart review studies can be undertaken to provide robust naturalistic data to inform evaluations of treatment patterns, resource utilization, costs of care, clinical outcomes and safety.
Cross-sector collaborations to perform R&D are on the increase, but they do involve various risks for each of the partners. Project risks in such ventures are explored through a case study, a successful collaboration involving an Australian Cooperative Research Centre and Ciba Vision, a division of the Swiss multi-national Novartis. The analysis examines the projects success factors and its risks. The reputation of researchers, the development of mutual trust among the partners, and the importance of credible commitments made at project initiation are three key factors contributing to the success of commercially focused R&D collaborations ...
This is a prospective, non-randomized multi-center multi-national study to evaluate the chimerism measured by STR and SNP in patients with hypoplastic R
Our experienced commercial leasing and property management attorneys draw from their deep understanding of the business of real estate to support a national client base of landlords and tenants. We work seamlessly with our clients in aggregating millions of square feet of real estate capital, resolving issues quickly and with clarity, which serves as the foundation of our reputation as "deal makers," not "deal breakers.". Backed by decades of experience in office, retail and industrial commercial leasing transactions, as well as property management, Dykema regularly represents institutional and entrepreneurial property owners including REITs, multi-national pension funds, insurance companies, developers and mortgagees. Our clients also include leasing agents and managers of commercial properties, Fortune 500 and other national companies, and developer landlords.. Keeping a sharp focus on client business objectives, we act quickly and efficiently to resolve leasing and property management issues. ...
I grew up in Texas on a cattle ranch. I was fortunate to be raised by my grandparents after the death of my mother. My grandmothers best friend was Betty Moorman, a wealthy White lady, who in effect adopted my family. So I had the interesting life of growing up poor, but knowing what it was like to be rich. I went to private high school, paid for by Betty. I excelled in school, and received an academic scholarship to Southern Methodist University in Dallas. After graduating I worked in as an electrical engineer, before getting into sales. In 1992 I bought my own sales company, and built a multi-national six office organization, which I sold in 1996. Presently I am an executive in an IT consulting firm, and serve on the board of The Adoption Exchange in St. Louis. In short, I know what it is like to be poor, to be rich, and to give back. This blog is meant to showcase the true meaning of being a proud Black Conservative in America. If you like what you read, please click "Follow This Blog" or ...
I grew up in Texas on a cattle ranch. I was fortunate to be raised by my grandparents after the death of my mother. My grandmothers best friend was Betty Moorman, a wealthy White lady, who in effect adopted my family. So I had the interesting life of growing up poor, but knowing what it was like to be rich. I went to private high school, paid for by Betty. I excelled in school, and received an academic scholarship to Southern Methodist University in Dallas. After graduating I worked in as an electrical engineer, before getting into sales. In 1992 I bought my own sales company, and built a multi-national six office organization, which I sold in 1996. Presently I am an executive in an IT consulting firm, and serve on the board of The Adoption Exchange in St. Louis. In short, I know what it is like to be poor, to be rich, and to give back. This blog is meant to showcase the true meaning of being a proud Black Conservative in America. If you like what you read, please click "Follow This Blog" or ...
Xebec Adsorption Inc. is a global provider of gas generation, purification and filtration solutions for the industrial, energy and renewables marketplace. Its customers range from small to multi-national corporations and governments looking to reduce their carbon footprints. Headquartered...
Any intelligent person forced to take part in an office team-building exercise knows how easy it would be to slip from controlled corporate rage to homicide. The creators of Severance understand that feeling. In place of traditional slasher film targets (such as obnoxious teenagers) they have substituted the people we most want to see mutilated and murdered: co-workers.. When their bus breaks down somewhere in an Eastern European forest, several sales employees of the multi-national Palisade Defence have to schlep their belongings to the nearest hotel. There they await instructions from the American executive who planned their trip. The hotel turns out to be a moldy inn equipped with no amenities except weird pie. And every step outside the place lands the unhappy employees in (often excruciating) peril. Acting Talent ...
Rome, 1 April 1997 (RFE/RL) - Italys Defense Minister, Beniamino Andreatta, today acknowledged a multi-national security mission into Albania will be risky, but he said it will go ahead within 10 ...
Cross-sector collaborations to perform R&D are on the increase, but they do involve various risks for each of the partners. Project risks in such ventures are explored through a case study, a successful collaboration involving an Australian Cooperative Research Centre and Ciba Vision, a division of the Swiss multi-national Novartis. The analysis examines the projects success factors and its risks. The reputation of researchers, the development of mutual trust among the partners, and the importance of credible commitments made at project initiation are three key factors contributing to the success of commercially focused R&D collaborations ...
Lisa Jackson, former head of the EPA and current Apple executive, explains how the company tries to minimize its carbon footprint in its multi-national supply chain.
Ugandas oil and gas are at the heart of campaigns for presidential elections taking place this month. But the resources are shrouded in mystery, as no one, except the Museveni regime, knows the details of the contracts the government has signed with multi-national companies. Ugandans need to keep an eye on these resources and demand answers on how they will be used to better their lives.. ...
The Indian Medical Association (IMA) has accused US multi-national companies of selling recycled prosthesis in India at cheaper prices.
The HACEK organisms (Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens, and Kingella species) are rare causes of infective endocarditis (IE). The objective of this study is to describe the clinical characteristics and outcomes of patients with HACEK endocarditis (HE) in a large multi-national cohort. Patients hospitalized with definite or possible infective endocarditis by the International Collaboration on Endocarditis Prospective Cohort Study in 64 hospitals from 28 countries were included and characteristics of HE patients compared with IE due to other pathogens. Of 5591 patients enrolled, 77 (1.4%) had HE. HE was associated with a younger age (47 vs. 61 years; p,0.001), a higher prevalence of immunologic/vascular manifestations (32% vs. 20%; p,0.008) and stroke (25% vs. 17% p = 0.05) but a lower prevalence of congestive heart failure (15% vs. 30%; p = 0.004), death in-hospital (4% vs. 18%; p = 0.001) or after 1 year follow-up (6% vs. 20%; p = 0.01) ...
These results showed that reduced wellbeing is observed in UI. This effect is observed in all aspects of wellbeing and most sub-groups of UI sufferers. Factors which reflect greater severity of UI lead to a greater reduction in wellbeing. Lifestyle influences wellbeing and those with UI who exercise less frequently or have sex infrequently are especially likely to report reduced wellbeing. Wellbeing decreases as a function of the severity of UI and reductions in HRQol. Again, these changes reflect all aspects of wellbeing measured by WEMWBS. Previous analyses [13] showed that when both quality of life (ICIQ-LUTSqol) and symptom severity (ICIQ-UI Short Form) were included in the same regression analysis, the only significant effect on mental well-being was ICIQ-LUTSqol. This shows that UI symptoms do not directly affect mental well-being, but that symptoms influence quality of life, which in turn influences well-being.. This is the first multi-national study which has examined the impact of UI on ...
Frequency and predictors of the lupus low disease activity state in a multi-national and multi-ethnic cohort. Vera Golder, Rangi Kandane-Rathnayake, Alberta Hoi, Molla Huq, Worawit Louthrenoo, Yuan An, Zhan Li, Shue Luo, Sargunan Sockalingam, Chak Lau, Alfred Lee, Mo Mok, Aisha Lateef, Kate Franklyn, Susan Morton, Sandra Navarra, Leonid Zamora, Yeong-Jian Wu, Laniyati Hamijoyo, Madelynn Chan, Sean ONeill, Fiona Goldblatt, Eric Morand, Mandana Nikpour, for the Asia-Pacific Lupus Collaboration Arthritis Research & Therapy 2016, 18:260 (9 November 2016) ...
Founded in 1991, Sofor Oy is a Finnish IT service provider with offices in Kauhava, Helsinki, Tampere, and Vaasa. With an extensive data center based on Citrix XenServer, Sofor specializes in mobile solutions, business digitization and management, and capacity services, and offers hosted applications that include Microsoft Windows, Lotus Notes, Linux web and database services, as well as Citrix XenApp-hosted shared desktops providing remote customer desktops.. Sofor serves mostly Finnish customers plus a few multi-national businesses. The verticals they serve include heavy industry; construction, steel, manufacturing and some public-sector businesses. The applications their customers host/run within their infrastructure are mainly office worker, productivity-based, with some ERM applications.. Sofor sought a solution to minimize or eliminate the risk of sophisticated, persistent attacks. They found that traditional security solutions dont respond quickly enough and are not as scalable as ...
Most research on R&D internationalisation focuses on comparative analysis of location factors at the national level of analysis. Very little work, however, has taken place in this field for the sub-national regional location behavior of multi-national enterprises (MNE). The paper contributes to the existing research by providing evidence on the determinants of foreign technological activities at the sub-national level for Germany, which hosts the largest share of foreign R&D within the EU27 and features the highest cross-regional dispersion of patented research. Using a pooled count data model, we estimate the effect of various sources for externalities on the extent of foreign technological activity across regions. Particular attention is paid to the role of local knowledge spillovers, technological specialization and diversification. We differentiate foreign and domestic sources of specialisation and account for region and sector-specific influences. This is the first time that the ...
A recent survey reveals that 600 multi-national experts believe renewables are cost competitive with fossil fuels - good news for solar panel solutions!
Fujitsu today at Fujitsu Forum 2013 highlights growing momentum as it continues to develop its services business across EMEA&I (Europe, the Middle East, Africa and India). As Fujitsu accelerates the globalization of its services portfolio, so the European region has seen significant new wins and Fujitsu reports an increase in multi-national opportunities.
Apply a conductive floor finish to a concrete floor with our system of ESD floor strippers, sealants, paints and waxes. We are a multi-national distributor of ESD & static control products.
FInOrIC, etymologically derived from our business line of Fine Inorganic, Organic and Industrial Chemicals, offers chemicals for Oil & Gas Exploration, Hydraulic Fracturing, Production, Stimulation, Coiled Tubing, Food & Feed Ingredients, Mineral Fortifiers and Pharmaceutical Excipients, in 55 countries across 5 continents. Backed by company owned & operated full-fledged chemical manufacturing facilities in Pleasanton, Midland & Houston, Texas and and El Reno, Oklahoma along with associated manufacturing sites in India, UAE and China we are a truly multi-national chemical manufacturer and distributor.. We offer 24/7 well-site deliveries and bulk ISO tank well-site logistics. ...
So we arrive at April 1st with the beer world witnessing great change. In the past few years the multi-national light lager brewers, led by Anheuser Busch InBev, SAB Miller and Molson Coors have recognized the need to go beyond light lager and have created craft beers of their own like Shock Top and Blue Moon. They have avoided linking these beers to their heritage brands by creating breweries that dont exist. Their "Argo like" creations have been very successful. To that we say, "Bravo, gentlemen.". Read More , ...
The wobbly global economy is set to further stunt growth in Chinas domestic technology market, leading Beijing to offer even greater financial incentives to encourage more hi-tech imports to the country.. The Chinese government will offer 2.5bn yuan (£249m) in loan subsidies to importers of unspecified advanced technologies and raw materials, a 25 per cent increase on last years sum, according to Reuters.. Chinese imports actually fell 2.6 per cent in August from the same period in 2011 while exports rose only 2.7 per cent, less than expected.. Beijing will therefore be hoping this latest cash injection will help put its slowing economic growth back on track and reduce an embarrassingly high trade surplus which according to some estimates stood at over $26bn in August.. Forresters latest report, China Tech Market Outlook: 2012 To 2013, could be some cause for concern, however.. The report claims that domestic and multi-national tech vendors in the PRC are all seeing a slow-down in their ...
Iqbal Yousuf is Managing Director Aptech Pakistan. He carries with him ten years of rich experience of Computer Education programme in the country. Since his joining the Aptech Pakistan he has proved his professional mettle and is successfully taking the institute towards prestigious niche with nurturing expansion projects across Pakistan. Earlier, Iqbal Yousuf had also been running a Pakistan-based multi-national IT consultancy NDC as COOTell us about Aptech Computer Education as an institute?…Read More. ...
Procter & Gamble Co., also known as P&G, is an American multi-national consumer goods corporation headquartered in downtown Cincinnati, Ohio, founded in 1837 by British American William Procter and Irish American James Gamble. It primarily specializes in a wide range of cleaning agents and personal care and hygienics products. Before the sale of Pringles to the Kellogg Company, its product portfolio also included foods, snacks and beverages. In 2014, P&G recorded $83.1 billion in sales. On August 1, 2014, P&G announced it was streamlining the company, dropping and selling off around 100 brands from its product portfolio in order to focus on the remaining 65 brands, which produced 95% of the companys profits. A.G. Lafley-the companys chairman, president, and CEO until October 31, 2015-said the future P&G would be "a much simpler, much less complex company of leading brands thats easier to manage and operate". David Taylor is the current president and CEO of Procter & Gamble. Candlemaker ...
When we saw the recent news that the U.S. House had passed a massive tax cut for multi-national corporations that would add over $1.5 trillion to the national debt, we
The multi-national food giant Danone has been accused of misleading mothers with a marketing campaign that warned they might not be providing enough breast milk to their babies. The com
Chem-Trend, LP USA. Multi-national manufacturers of release agents for applications in the general rubber, tire, polyurethane, composites, thermoplastics and die casting industries. List of employment opportunities. Links to related sites. Part of the Freudenberg Group ...
The Iraqi parliament Tuesday approved an agreement that will permit 6,000 troops from the United Kingdom, Australia, Romania, and Estonia to remain in the country for a limited time after the current UN mandate authorizing the multi-national force in Iraq expires on December 31, 2008. The vote came after Sunni speaker Mahmoud al-Mashhadani offered his resignation. … [read more] ...
Define Juvenile Periodontitis. Juvenile Periodontitis synonyms, Juvenile Periodontitis pronunciation, Juvenile Periodontitis translation, English dictionary definition of Juvenile Periodontitis. n dentistry the inflammation of periodontal tissue n. 1. inflammatory disease of the periodontium. 2. pyorrhea . Noun 1. periodontitis - a disease that...
ID C9R3L9_AGGAD Unreviewed; 404 AA. AC C9R3L9; DT 24-NOV-2009, integrated into UniProtKB/TrEMBL. DT 24-NOV-2009, sequence version 1. DT 25-OCT-2017, entry version 39. DE SubName: Full=Molybdopterin molybdenumtransferase {ECO:0000313,EMBL:ACX82405.1}; GN OrderedLocusNames=D11S_1018 {ECO:0000313,EMBL:ACX82405.1}; OS Aggregatibacter actinomycetemcomitans serotype C (strain D11S-1) OS (Actinobacillus actinomycetemcomitans). OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; OC Pasteurellaceae; Aggregatibacter. OX NCBI_TaxID=668336 {ECO:0000313,EMBL:ACX82405.1, ECO:0000313,Proteomes:UP000002569}; RN [1] {ECO:0000313,EMBL:ACX82405.1, ECO:0000313,Proteomes:UP000002569} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=D11S-1 {ECO:0000313,EMBL:ACX82405.1, RC ECO:0000313,Proteomes:UP000002569}; RX PubMed=19820097; DOI=10.1128/JB.01203-09; RA Chen C., Kittichotirat W., Si Y., Bumgarner R.; RT "Genome sequence of Aggregatibacter actinomycetemcomitans serotype c RT strain D11S-1."; ...
BACKGROUND: Lyme disease, the most common tickborne disease in the United States, is caused exclusively by Borrelia burgdorferi sensu stricto in North America. The present study evaluated the genotypes of ,400 clinical isolates of B. burgdorferi recovered from patients from suburban New York City with early Lyme disease associated with erythema migrans; it is the largest number of borrelial strains from North America ever to be investigated. METHODS: Genotyping was performed by restriction fragment-length polymorphism polymerase chain reaction analysis of the 16S-23S ribosomal RNA spacer and reverse line blot analysis of the outer surface protein C gene (ospC ...
Background. Only a subset of individuals infected with Trypanosoma cruzi develop chronic Chagas cardiomyopathy (CCC). Familial aggregation of CCC in areas of endemicity indicates that susceptibility may be genetic, which may be a plausible explanation for why only one-third of T. cruzi-infected individuals develop CCC. The monocyte chemoattractant protein-1 (CCL2/MCP-1) has been shown to enhance the uptake of T. cruzi in murine macrophages and to up-regulate the inducible nitric oxide synthase/nitic oxide system, with a consequent increased production of nitric oxide that controls the replication of the parasite.. Methods. We assessed CCL2 variants at position -2518A/G, which are known to influence transcriptional activity, by polymerase chain reaction and restriction fragment-length polymorphism in 245 individuals, all of whom were infected with T. cruzi. One hundred sixty-nine patients had CCC, and 76 were asymptomatic.. Results. Genotype distributions differed between the CCC and asymptomatic ...
VINAYAK KUMAR (Biochemistry) is a senior in the Roy and Diana Vagelos Scholars Program in the Molecular Life Sciences. Vinayak has been working in Professor Mark Kahns lab at the Perelman School of Medicine, researching factors that affect the development of organ structure. He has also published an article in the Penn Bioethics Journal and serves as a research peer advisor for the Penn Undergraduate Chemistry Society and as the CEO of a multi-national, student-based non-profit organization that creates and implements projects to improve the quality of life in communities in need ...
Mad Hedge: No, I sold most of my positions in June. The risk was low in March, but not so low in June, and its even greater now. The PE multiple on the S&P 500 has just jumped from 10 to 20 in six months. Historically, a 20 multiple is a terrible time to enter the market. Markets are discounting a "V"-shaped recovery, which we are not going to get. I think well get more of a "square root" shaped recovery, a "V" followed by sideways to a gradually upward sloping grind. Weve already had the "V". Markets are overpriced. I dont see how we can have huge economic growth with capital-constrained banks, catatonic consumers, and commercial real estate troubles up the wazoo. One of the only positives is the weak dollar, which makes everything we sell to the rest of the world cheaper. This is good for our multi-national companies, good for our exporters. So far, the dollar is on a grinding, controlled move down, which is good. But if the dollars fall accelerates, it would not be good. A real dollar ...
Mad Hedge: No, I sold most of my positions in June. The risk was low in March, but not so low in June, and its even greater now. The PE multiple on the S&P 500 has just jumped from 10 to 20 in six months. Historically, a 20 multiple is a terrible time to enter the market. Markets are discounting a "V"-shaped recovery, which we are not going to get. I think well get more of a "square root" shaped recovery, a "V" followed by sideways to a gradually upward sloping grind. Weve already had the "V". Markets are overpriced. I dont see how we can have huge economic growth with capital-constrained banks, catatonic consumers, and commercial real estate troubles up the wazoo. One of the only positives is the weak dollar, which makes everything we sell to the rest of the world cheaper. This is good for our multi-national companies, good for our exporters. So far, the dollar is on a grinding, controlled move down, which is good. But if the dollars fall accelerates, it would not be good. A real dollar ...
What happens to a technology artifact after it is adopted? It has to evolve within its particular context to be effective; otherwise, it will become part of the detritus of change, like the many genes without a discernible function in a living organism. In this paper, we report on a study of post-adoptive behavior that examined how users modified and innovated with technology artifacts. We uncovered three types of modifications made to technology artifacts: personalization, customization, and inventions. Personalization attempts are modifications involving changes to technology parameters to meet the specificities of the user; customization attempts adapt the technology parameters to meet the specificities of the users environment; and inventions are exaptations conducted to the technology artifact. This paper presents a grounded theoretic analysis of the post-adoptive behavior based on in-depth interviews with 20 software engineers in one multi-national organization. We identify a life-cycle ...
Promofood Specialty Foods is a multi-national specialty food importer specializing in meat, cheese, groceries, spices, fruit, bakery, beverages and many other products from Europe.
A multi-national team of scientists from the University of Utah, the Museo del Desierto in Saltillo in Mexico and the Royal Tyrrell Museum from Alberta, Canada
San Mateo, CA-based NetGravity said Internet publishers and networks in Latin America including Cade and Zaz in Brazil, InfoAcces in Mexico and Prima in Argentina have signed on as NetGravity AdServer customers. Brazil represents over 47 percent of Latin Americas Internet market. Cade is the largest single Web service in Brazil. "Cade serves over 900,000 ads a day," said Fabio Oliveira, CEO of Cade. "The market in Latin America is booming and by adopting NetGravity AdServer. . .Cade expects to increase the level of comfort and consequently the budgets of local and multi-national advertisers." ...
An enterprise information system (EIS) is any kind of information system which improves the functions of enterprise business processes by integration. This means typically offering high quality of service, dealing with large volumes of data and capable of supporting some large and possibly complex organization or enterprise. An EIS must be able to be used by all parts and all levels of an enterprise.[1]. The word enterprise can have various connotations. Frequently the term is used only to refer to very large organizations such as multi-national companies or public-sector organizations. However, the term may be used to mean virtually anything, by virtue of it having become the latest corporate-speak buzzword.[citation needed]. ...
Perio Horizons Dental Health Page discusses important topics for the dental consumer and the health care provider and offer advice on treatment, prevention, and wellness.
Background Aggregatibacter actinomycetemcomitans is genetically heterogeneous and comprises distinct clonal lineages that may have different virulence potentials. However, limited information of the strain-to-strain genomic variations is available. Methodology/Principal Findings The genome sequences of 11 A. actinomycetemcomitans strains (serotypes a-f) were generated de novo, annotated and combined with three previously sequenced genomes (serotypes a-c) for comparative genomic analysis. Two major groups were identified; serotypes a, d, e, and f, and serotypes b and c. A serotype e strain was found to be distinct from both groups. The size of the pangenome was 3,301 genes, which included 2,034 core genes and 1,267 flexible genes. The number of core genes is estimated to stabilize at 2,060, while the size of the pangenome is estimated to increase by 16 genes with every additional strain sequenced in the future. Within each strain 16.7-29.4% of the genome belonged to the flexible gene pool. Between any
Objective Considering the relevance of tumor necrosis factor-α (TNF-α) in the pathophysiology of juvenile idiopathic arthritis (JIA), it is likely that polymorphisms in its promoter area may be relevant in disease susceptibility and activity. We investigated if clinical measures of JIA activity and TNF-α serum concentrations were associated with TNF-α -308 genotypes. Methods Portuguese patients with JIA in 5 pediatric rheumatology centers were recruited consecutively, along with a control group of healthy subjects. Demographic and clinical data and blood samples were collected from each patient. DNA was extracted for analysis of TNF-α gene promoter polymorphisms at position -308 by restriction fragment-length polymorphism. Results One hundred fourteen patients and 117 controls were evaluated; 57% of patients presented the oligoarticular subtype, 25% the polyarticular subtype, 8% the systemic subtype, and 9% had enthesitis-related arthritis and 5% psoriatic arthritis. Twenty-four percent of ...
Oral squamous cell carcinoma (OSCC) is a major health problem in many developing countries, representing more than 25% of all new cancer cases in some countries such as India and Sri Lanka. Cigarette smoking, smokeless tobacco (ST), alcohol use and chewing of betel quid (BQ) are the main risk factors associated with OSCC development. Infection with highrisk Human papillomavirus (HPV) is an emerging risk factor, particularly for oropharyngeal cancers. Most of the OSCC cases are diagnosed at advanced stages, being one of the factors related to the high mortality rate of this cancer. A better understanding of the molecular biology of OSCC development might lead to improved methods related to detection, assessing prognosis and novel treatments of this malignancy. Over the recent years, microarray-based technologies have become commonly used techniques for analyzing gene expression and chromosomal alterations in human cancers and other disease conditions. These high-throughput technologies enable ...
Job prospects. A variety of job profiles are offered to food tech/science students. Quiet often, they find employment in food manufacturing industries such as - Nestle, ITC Limited, Mondelez International (earlier knows as Cadbury), Dabur, Amul, Parle, Jubiliant FoodWorks(Dominos), MTR foods , Haldiram etc. Job opportunities are also available in retail, agro-products and the public sector. Certain openings are also present in the defence sector.. Food technology could also be pursued as a doctoral subject. Research scholars can qualify entrance examinations and are entitled for stipend provided by scientific/academic bodies such as- ICMR, UGC or CSIR. After gaining an experience of 3-4 years, individuals are provided with excellent remuneration in this field.. Roles and responsibilities-. Many food tech/science graduates get jobs as food quality officers in the multi-national food companies. Their primary role is to assess and maintain the quality of food before it is out for distribution. They ...
The use of recycled PET in the food sector is being held back by poor quality control and by brand owners misconceptions, according to PET bottle molder APPE.. The company, which says it is the largest food-grade PET recycler in Europe, is investing €10m at its recycling plant in Beaune, France to increase food-grade rPET output by 40 percent. But, European Plastics News reported, further expansions could be constrained by low supply of post-consumer PET.. Frédéric Blanchard, plant director of the Beaune facility, said the lack of supply is causing the price of post-consumer PET bales to rise to record highs. He said recyclers costs also include blending, process controls and changeovers. But he said brand owners think incorrectly that rPET should be cheaper than its virgin cousin.. In other packaging news, multi-national cosmetics company Lush has outsourced the recycling of its black polypropylene cosmetics pots from its shops in the north of England, to eco-manufacturer Remarkable, ...
A medium-sized, retrospective (observational) study of several thousand women post knee- or hip-joint replacement indicated that those who were taking hormone replacement therapy (HRT) had a lower risk of needing revision of their implant over a period of 18 months to 6 years post-surgery (average follow-up of 3 years). And there appeared to be a dose-response relationship. The study was published in the Annals of Rheumatic Diseases.. The multi-national group of... ...
Further detail on the demographics of the modern Chinese knowledge workforce in combination with time spent living abroad or in mainland China.. Self Starters were born before and during the Cultural Revolution and lived through the hardest parts of communism. They have lived only in Mainland China, are generally conservative, are focused on social displays of success, and were immediately entrepreneurial when the economy opened up in 1979. Self Starters run Chinese companies and believe in hiring local, not foreign, talent.. Conformists were born during and just after the Cultural Revolution, have lived only in Mainland China, and accept communism and the information provided to them by the government. They work at Chinese National companies.. Optimists are part of the Opportunity Generation, born after 1987, and are all products of the one-child policy. They have only lived in Mainland China but may have Western exposure through employment with a multi-national company. Generally pleased with ...
PG-13) ★★☆☆☆. Tyler Perry makes a go at being a conventional action-hero in this reprisal of Morgan Freemans role in previous film adaptations of James Pattersons novels. A murderer, known as Picasso (Matthew Fox), is killing people and leaving Cubist-style drawings at the scenes of his crimes. He appears to have his sights set on a multi-national industrialist (Jean Reno). But not if Alex Cross (Perry) has anything to say about it. Revenge is game here, and while Perry does OK, the film just isnt very interesting.. ...
Geneva, Switzerland - Unilabs, a leading medical diagnostic services company, today announces that Jos Lamers has been appointed CEO succeeding Jean-Paul Rigaudeau, effective October 7, 2013.. Jos Lamers joins Unilabs as CEO, from his previous position as CEO of Nucletron, a radiotherapy company and global leader in brachytherapy that was acquired by Elekta in 2011. Prior to his CEO role at Nucletron, Jos was a Regional President and member of the Executive Management Board at Eurofins Scientific. He succeeds Jean-Paul Rigaudeau, who will be leaving after over four years of successfully leading the Company.. "The Company is pleased that Jos Lamers will join as CEO and we warmly welcome him to Unilabs. Jos has a proven track record of leading multi-national healthcare organizations, and his valuable experience makes him the ideal leader to build upon the Companys strong foundation and take Unilabs to its next stage of development," said Paul Hökfelt, Chairman of the Board of Unilabs. "Unilabs ...
VITA NOVA is a Eclectic Prog / Progressive Rock artist from Multi-National. This page includes VITA NOVAs : biography, official website, pictures, videos from YouTube, MP3 (free download, stream), related forum topics, news, tour dates and events, live eBay auctions, online shopping sites, detailled reviews and ratings (top albums) and the full discography of albums: studios, live, boxset/compilations, singles/EPs/fan club/promo releases on CD, vinyl / lp or cassette and videos released on Blu-ray, DVD or VHS
So, youre a multi-national, multi-billion dollar corporation and you give 2,200 employees five hours notice that they need to find another job. Sure, you kind of follow federal law and give them 60 days of severance pay because you dont want to get sued, fined and have to pay for all those legal fees, but […]. ...
For more than three decades, deforestation in the Amazon has been driven by the expansion of pasturelands for cattle production. Pasture area also expanded rapidly because soils found throughout much of the region are poor in nutrients following forest slash and burn, and crop production cannot be maintained in the face of degradation of soils and lost vegetation productivity. In the late 1990s, multi-national corporations such as Cargill began investing in infrastructure throughout the south-central Amazon. New river ports, fertilizer and mechanization have fueled explosive growth in the crop agricultural sector, especially for soybeans. For example, in the State of Mato Grosso, soybean agriculture has increased at a rate of 1,000 to 2,000 km2 per year since 2000, making it the fastest growing form of land use regionally. Much of this deforestation is now being driven directly by conversion to soybean fields, the soy oil and meal from which are being used largely by the growing industrial ...
Vancouver - Functional Technologies Corp. has entered into new testing and development agreements for its acrylamide-preventing Acryleast yeasts.. The company says testing of its acrylamide-preventing yeasts in baking bread have shown acrylamide reductions of 90 per cent with no discernible differences in quality and taste in the baked bread and no changes in the baking process.. The companys AP-preventing yeasts have already been well received in the baking and other food industries, with a collaboration partnership signed in early 2011 with an undisclosed leading multi-national corporation and ongoing partnership and testing discussions with companies in a variety of food-related sectors.. This expanding interest extends across different segments in the food industry and communities, from upstream food suppliers as well as end-user food producers that represent top tier, national and multinational food ingredient and producer companies in North America and Europe, says the ...
Toni Morrison dubbed Bill Clinton the "first black president." Well, Im dubbing Obama the first woman. Hillary does not represent me or my woman-ness or my feminism or anything like that, and I cant see how she represents anybody elses, either. Despite her recently hyped rejection of CAFTA, she has traditionally voted with the GOP for trade agreements that victimize third-world women and children and outsource U.S. labor. Obama hasnt. She has supported an imperialist war that creates worse conditions for Iraqi women than Saddams regime did. Obama does not. She is no challenge to the current soft-fascist, soft-money regime in the U.S. (the multi-national corporate master of us all) because she thought she needed it to win her place in history. Obama didnt need them after all.. And lately, she seems to be stooping even lower by employing the decades-old GOP, Good Ol Boy, campaign strategy: Dividing working-and middle-class voters around the issue of race rather than offering them anything ...
Looking for online definition of Actinobacillus actinomycetemcomitans in the Medical Dictionary? Actinobacillus actinomycetemcomitans explanation free. What is Actinobacillus actinomycetemcomitans? Meaning of Actinobacillus actinomycetemcomitans medical term. What does Actinobacillus actinomycetemcomitans mean?
An actinomycetemcomitans can cause localized juvenile periodontitis and certain types of adult periodontitis. Optimal treatment of periodontal disease caused by this microorganism requires systemic antibiotic therapy in addition to mechanical debride
MPGI has setup institutions from Junior to Higher Education Levels. MPGI Offers the best Placement Opportunities to its students in multi-national companies. MPGI offers degree level courses in engineering, management, pharmacy, fashion designing, computer applications, mass communication and dental.
0165] (1) Wilson M, Henderson, B. Virulence factors of A. actinomycetemcomitans revenant to the pathogenesis of inflammatory periodontal diseases. FEMS 1995:17:365-379. [0166] (2) Nowotny A, Behling U H, Hammond B, et al. Release of toxic microvesicles by Actinobacillus actinomycetemcomitans. Infect Immun 1982:37:151-154. [0167] (3) Kaplan J B, Perry M B, MacLean L L, Furgang D, Wilson M E, Fine D H. Structural and genetic analyses of 0 polysaccharide from Actinobacillus actinomycetemcomitans serotype f. Infect Immun 2001:69:5375-5384. [0168] (4) Rosan B, Slots J, Lamont R J, Listgarten M A, Nelson G M. Actinobacillus actinomycetemcomitans fimbriae. Oral Microbiol Immunol 1988:3:58-63. [0169] (5) Inouye T, Ohta H, Kokeguchi S, Fukui K, Kato K. Colonial variation and fimbriation of Actinobacillus actinomycetemcomitans. FEMS microbiology letters 1990: 57: 13-17. [0170] (6) Kaplan J B, Schreiner H C, Furgang D, Fine D H. Population structure and genetic diversity of Actinobacillus ...
The module will include traditional lecture style content delivery but will be augmented significantly with various other learning activities. Learning activities include: • An individual assignment examining OD interventions in response to specific organisational problems • Analysis of DD-related case studies in small groups • Practical skills development through use of role play and video • Private study Action learning sets will also be facilitated as part of the small group working and to encourage self-directed and peer learning. This module offers international dimensions through presenting you with examples of Organisation Development originating from different countries including the emerging economies. International/global issues are also addressed in the context of Organisation Development within multi-national companies and Non-Government Organisations (NGOs) that operate in the developing world. There is also a focus on cross-cultural management issues and how this can impact ...

Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-LauritsenAggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen

Genomic DNA from Aggregatibacter actinomycetemcomitans strain HK1651 TypeStrain=False Application: ... nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen and Kilian 2006 ATCC® 700685D-5™ dried At least 5 µg in ... Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen and Kilian 2006 (ATCC® 700685™) Add to ...
more infohttps://www.atcc.org/en/Products/Nucleic_Acid_Proteins_and_Cell_Extracts/Genomic_DNA_and_RNA/From_Bacteria/700685D-5.aspx

Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-LauritsenAggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen

Genomic DNA from Aggregatibacter actinomycetemcomitans strain HK1651 TypeStrain=False Application: ... nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen and Kilian 2006 ATCC® 700685D-5™ dried At least 5 µg in ... Aggregatibacter actinomycetemcomitans (Klinger 1912) Nørskov-Lauritsen and Kilian 2006 (ATCC® 700685™) Add to ...
more infohttps://www.atcc.org/Products/All/700685D-5.aspx

Targeted delivery of a photosensitizer to Aggregatibacter actinomycetemcomitans biofilm  - Zurich Open Repository and ArchiveTargeted delivery of a photosensitizer to Aggregatibacter actinomycetemcomitans biofilm - Zurich Open Repository and Archive

Suci, P; Kang, S; Gmür, R; Douglas, T; Young, M (2010). Targeted delivery of a photosensitizer to Aggregatibacter ... Biofilm microcolonies of Aggregatibacter actinomycetemcomitans, a periodontal pathogen, were targeted with the multifunctional ... Biofilm microcolonies of Aggregatibacter actinomycetemcomitans, a periodontal pathogen, were targeted with the multifunctional ...
more infohttp://www.zora.uzh.ch/id/eprint/42943/

Aggregatibacter aphrophilus in a patient with recurrent empyema: a case report | springermedizin.deAggregatibacter aphrophilus in a patient with recurrent empyema: a case report | springermedizin.de

Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus and H. paraphrophilus ) is part of the normal oropharyngeal flora ... Aggregatibacter aphrophilus in a patient with recurrent empyema: a case report Autoren:. Lasantha Ratnayake William J Olver Tom ... Aggregatibacter aphrophilus in a patient with recurrent empyema: a case report. Zeitschrift:. Journal of Medical Case Reports ... Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus and H. paraphrophilus) is part of the normal oropharyngeal flora ...
more infohttps://www.springermedizin.de/aggregatibacter-aphrophilus-in-a-patient-with-recurrent-empyema-/9648510?fulltextView=true

Cytotoxic mechanisms of Aggregatibacter actinomycetemcomitans leukotoxin - Angela BrownCytotoxic mechanisms of Aggregatibacter actinomycetemcomitans leukotoxin - Angela Brown

Aggregatibacter actinomycetemcomitans is a Gram-negative pathogen that is the etiologic agent of localized aggressive ... Cytotoxic mechanisms of Aggregatibacter actinomycetemcomitans leukotoxin Brown, Angela C. Lehigh University, Bethlehem, PA, ... Cytotoxic mechanisms of Aggregatibacter actinomycetemcomitans leukotoxin. Brown, Angela C. / Lehigh University. $279,310. ... Cytotoxic mechanisms of Aggregatibacter actinomycetemcomitans leukotoxin. Brown, Angela C. / Lehigh University. $246,691. ...
more infohttp://grantome.com/grant/NIH/R00-DE022795-03

ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY OF CATHELICIDINS - Patent applicationANTIMICROBIAL AND ANTIBIOFILM ACTIVITY OF CATHELICIDINS - Patent application

0189] (25) Sliepen I, Van Essche M, Quirynen M, Teughels W. Effect of mouthrinses on Aggregatibacter actinomycetemcomitans ... 0008] In one aspect, there is provided an isolated cathelicidin conferring antimicrobial activity against Aggregatibacter ...
more infohttp://www.patentsencyclopedia.com/app/20120149631

Cardiobacterium Workup: Laboratory Studies, Imaging StudiesCardiobacterium Workup: Laboratory Studies, Imaging Studies

Aggregatibacter actinomycetemcomitans, Aggregatibacter aphrophilus, C hominis, Eikenella corrodens, and Kingella kingae), which ...
more infohttps://emedicine.medscape.com/article/214021-workup

KEGG GENOME: Aggregatibacter actinomycetemcomitans D11S-1KEGG GENOME: Aggregatibacter actinomycetemcomitans D11S-1

Genome sequence of Aggregatibacter actinomycetemcomitans serotype c strain D11S-1.. Journal. J Bacteriol 191:7378-9 (2009). DOI ... Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Aggregatibacter. Data source. GenBank (Assembly ...
more infohttp://www.genome.jp/kegg-bin/show_organism?org=aat

Aggregatibacter aphrophilus (Khairat 1940) Nørskov-Lauritsen and KiliaAggregatibacter aphrophilus (Khairat 1940) Nørskov-Lauritsen and Kilia

Aggregatibacter aphrophilus ATCC ® 33389-MINI-PACK™ Designation: NCTC 5906 TypeStrain=True Application: ATCC ® 33389-MINI-PACK ... nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Aggregatibacter aphrophilus (Khairat 1940) Nørskov-Lauritsen and Kilian 2006 ATCC® 33389-MINI-PACK™ frozen 6 ready-to-use vials ... Aggregatibacter aphrophilus (Khairat 1940) Nørskov-Lauritsen and Kilian 2006 (ATCC® 33389-MINI-PACK™) Strain Designations: NCTC ...
more infohttp://atcc.org/en/Products/Cells_and_Microorganisms/ATCC_Minis/33389-MINI-PACK.aspx

Aggregatibacter actinomycetemcomitansAggregatibacter actinomycetemcomitans

... It has been a long-held supposition of many doctors and researchers that dental ... Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid ... Aggregatibacter actinomycetemcomitans (Aa), is one of a number of organisms contributing to periodontal gum disease that can ...
more infohttps://www.roadback.org/research/aggregatibacter-actinomycetemcomitans/

Avaliação qualitativa, quantitativa e genotípica de Aggregatibacter actinomycetemcomitans...Avaliação qualitativa, quantitativa e genotípica de Aggregatibacter actinomycetemcomitans...

Aggregatibacter actinomycetemcomitans e Fusobacterium nucleatum são microrganismos gram-negativos presentes nos processos ... Aggregatibacter actinomycetemcomitans. Fusobacterium nucleatum. Biofilme subgengival. Gengivite. Periodontite crônica. Resumo ... Aggregatibacter actinomycetemcomitans. Fusobacterium nucleatum. Chronic periodontitis. Gingivitis. Subgingival biofilm. Resumo ... Aggregatibacter actinomycetemcomitans e Fusobacterium nucleatum são microrganismos gram-negativos presentes nos processos ...
more infohttp://www.teses.usp.br/teses/disponiveis/42/42132/tde-26082015-191740/pt-br.php

KEGG PATHWAY: Mismatch repair - Aggregatibacter actinomycetemcomitans D11S-1KEGG PATHWAY: Mismatch repair - Aggregatibacter actinomycetemcomitans D11S-1

Mismatch repair - Aggregatibacter actinomycetemcomitans D11S-1 [ Pathway menu , Organism menu , Pathway entry , Download KGML ...
more infohttp://www.genome.jp/kegg-bin/show_pathway?aat03430+D11S_1722

Gangliosides block Aggregatibacter Actinomycetemcomitans leukotoxin (LtxA)-mediated hemolysis. | Sigma-AldrichGangliosides block Aggregatibacter Actinomycetemcomitans leukotoxin (LtxA)-mediated hemolysis. | Sigma-Aldrich

Gangliosides block Aggregatibacter Actinomycetemcomitans leukotoxin (LtxA)-mediated hemolysis.. [Michael S Forman, Jason B ... Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The ...
more infohttps://www.sigmaaldrich.com/catalog/papers/22069577

Aggregatibacter | definition of Aggregatibacter by Medical dictionaryAggregatibacter | definition of Aggregatibacter by Medical dictionary

Aggregatibacter explanation free. What is Aggregatibacter? Meaning of Aggregatibacter medical term. What does Aggregatibacter ... Looking for online definition of Aggregatibacter in the Medical Dictionary? ... Here we report a case of the brain abscess caused by Aggregatibacter aphrophilus.. Aggregatibacter aphrophilus misidentified as ... Aggregatibacter. Ag·gre·ga·ti·bac·ter. (agrĕ-gati-baktĕr) Newly assigned name of a genus of gram-negative rods formerly called ...
more infohttps://medical-dictionary.thefreedictionary.com/Aggregatibacter

Toxins | Free Full-Text | Gangliosides Block Aggregatibacter Actinomycetemcomitans Leukotoxin (LtxA)-Mediated HemolysisToxins | Free Full-Text | Gangliosides Block Aggregatibacter Actinomycetemcomitans Leukotoxin (LtxA)-Mediated Hemolysis

Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The ... Gangliosides Block Aggregatibacter Actinomycetemcomitans Leukotoxin (LtxA)-Mediated Hemolysis Michael S. Forman, Jason B. ... Forman, M.S.; Nishikubo, J.B.; Han, R.K.; Le, A.; Balashova, N.V.; Kachlany, S.C. Gangliosides Block Aggregatibacter ... Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The ...
more infohttps://www.mdpi.com/2072-6651/2/12/2824/xml

Pyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature ReviewPyogenic Ventriculitis Complicating Aggregatibacter aphrophilus Infective Endocarditis: A Case Report and Literature Review

... ... reports on a fatal case of a previously well 42-year-old alcoholic woman with infective endocarditis caused by Aggregatibacter ...
more infohttps://www.hindawi.com/journals/cjidmm/2009/971735/abs/

Aggregatibacter - WikipediaAggregatibacter - Wikipedia

Nov., Aggregatibacter aphrophilus comb. Nov. And Aggregatibacter segnis comb. Nov., and emended description of Aggregatibacter ... Nov., Aggregatibacter aphrophilus comb. Nov. And Aggregatibacter segnis comb. Nov., and emended description of Aggregatibacter ... Nov., Aggregatibacter aphrophilus comb. Nov. And Aggregatibacter segnis comb. Nov., and emended description of Aggregatibacter ... Aggregatibacter is a genus in the phylum Proteobacteria (Bacteria), which contains three species, namely: A. ...
more infohttps://en.wikipedia.org/wiki/Aggregatibacter

Phosphorylcholine is located in Aggregatibacter actinomycetemcomitans fimbrial protein Flp 1Phosphorylcholine is located in Aggregatibacter actinomycetemcomitans fimbrial protein Flp 1

... Ihalin, Riikka Umeå University, ... Our aims were to determine the frequency of ChoP display among Aggregatibacter actinomycetemcomitans strains, to clarify which ... Aggregatibacter actinomycetemcomitans, Serotypes, Periodontitis, Phosphorylcholine, Fimbriae, Flp1, C-reactive protein, Serum ...
more infohttp://umu.diva-portal.org/smash/record.jsf?pid=diva2%3A1268262&c=3&searchType=LIST_LATEST&language=en&query=&af=%5B%5D&aq=%5B%5B%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all

Aggregatibacter actinomycetemcomitans - WikipediaAggregatibacter actinomycetemcomitans - Wikipedia

nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... Type strain of Aggregatibacter actinomycetemcomitans at BacDive - the Bacterial Diversity Metadatabase. ... Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans) is a Gram-negative, facultative ... suggesting the new genus Aggregatibacter for them. It is one of the bacteria that might be implicated in destructive ...
more infohttps://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans

Oil Essential Mouthwashes Antibacterial Activity against Aggregatibacter actinomycetemcomitans: A Comparison between...Oil Essential Mouthwashes Antibacterial Activity against Aggregatibacter actinomycetemcomitans: A Comparison between...

nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter ... R. C. V. Casarin, E. D. Ribeiro, F. S. Mariano, F. H. Nociti, M. Z. Casati, and R. B. Gonçalves, "Levels of Aggregatibacter ... Aggregatibacter actinomycetemcomitans (Aa) is a gram-negative coccobacillus, facultative anaerobe, closely associated with the ... S. C. Kachlany, "Aggregatibacter actinomycetemcomitans leukotoxin: from threat to therapy," Journal of Dental Research, vol. 89 ...
more infohttps://www.hindawi.com/journals/ijd/2013/164267/

CF65 02195 - Oxaloacetate decarboxylase alpha subunit,putative - Aggregatibacter actinomycetemcomitans HK1651 - CF65 02195 gene...CF65 02195 - Oxaloacetate decarboxylase alpha subunit,putative - Aggregatibacter actinomycetemcomitans HK1651 - CF65 02195 gene...

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Aggregatibacter › ... tr,X2JQV5,X2JQV5_AGGAC Oxaloacetate decarboxylase alpha subunit,putative OS=Aggregatibacter actinomycetemcomitans HK1651 OX= ...
more infohttps://www.uniprot.org/uniprot/X2JQV5

Small Things Considered: Aggregatibacter actinomycetemcomitans: A Unique Exotoxin-Producing Oral BacteriumSmall Things Considered: Aggregatibacter actinomycetemcomitans: A Unique Exotoxin-Producing Oral Bacterium

... the Gram-negative Aggregatibacter actinomycetemcomitans. For readers with an interest in taxonomy, this microbe was originally ... Aggregatibacter actinomycetemcomitans: A Unique Exotoxin-Producing Oral Bacterium by Pedro Valero-Guillén ... Zijnge V, Kieselbach T, & Oscarsson J (2012). Proteomics of protein secretion by Aggregatibacter actinomycetemcomitans. PloS ... the Gram-negative Aggregatibacter actinomycetemcomitans. For readers with an interest in taxonomy, this microbe was originally ...
more infohttps://schaechter.asmblog.org/schaechter/2013/07/aggregatibacter-actinomycetemcomitans-a-unique-exotoxin-producing-oral-bacterium-.html

Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid...Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid...

Among these, Aggregatibacter actinomycetemcomitans (Aa), but not other candidate pathogens, induced hypercitrullination in host ... Aggregatibacter actinomycetemcomitans generates citrullinated autoantigens involved in rheumatoid arthritis through its pore- ... Aggregatibacter actinomycetemcomitans generates citrullinated autoantigens involved in rheumatoid arthritis through its pore- ... Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid ...
more infohttps://stm.sciencemag.org/content/8/369/369ra176

DIGITAL.CSIC: Variability in the response of human dendritic cells stimulated with Porphyromonas gingivalis or Aggregatibacter...DIGITAL.CSIC: Variability in the response of human dendritic cells stimulated with Porphyromonas gingivalis or Aggregatibacter...

Variability in the response of human dendritic cells stimulated with Porphyromonas gingivalis or Aggregatibacter ... response of human dendritic cells to stimulation with different concentrations of Porphyromonas gingivalis or Aggregatibacter ...
more infohttps://digital.csic.es/handle/10261/56113

Aggregatibacter actinomycetemcomitans H-NS promotes biofilm formation and alters protein dynamics of other species within a...Aggregatibacter actinomycetemcomitans H-NS promotes biofilm formation and alters protein dynamics of other species within a...

Aggregatibacter actinomycetemcomitans H-NS promotes biofilm formation and alters protein dynamics of other species within a ... Aggregatibacter actinomycetemcomitans is a Gram-negative organism, strongly associated with aggressive forms of periodontitis. ... Aggregatibacter actinomycetemcomitans, H-NS, oral biofilm, oral microbiology, aggressive periodontitis, proteomics Nationell ...
more infohttp://umu.diva-portal.org/smash/record.jsf?pid=diva2%3A1213639&c=47&searchType=SIMPLE&language=sv&query=&af=%5B%5D&aq=%5B%5B%7B%22categoryId%22%3A%2211659%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
  • Very few cases of Aggregatibacter endocarditis in patients with pacemaker devices have been reported. (beds.ac.uk)