Age Factors: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.Spacecraft: Devices, manned and unmanned, which are designed to be placed into an orbit about the Earth or into a trajectory to another celestial body. (NASA Thesaurus, 1988)United States National Aeronautics and Space Administration: An independent Federal agency established in 1958. It conducts research for the solution of problems of flight within and outside the Earth's atmosphere and develops, constructs, tests, and operates aeronautical and space vehicles. (From U.S. Government Manual, 1993)TexasSpace Flight: Travel beyond the earth's atmosphere.British Columbia: A province of Canada on the Pacific coast. Its capital is Victoria. The name given in 1858 derives from the Columbia River which was named by the American captain Robert Gray for his ship Columbia which in turn was named for Columbus. (From Webster's New Geographical Dictionary, 1988, p178 & Room, Brewer's Dictionary of Names, 1992, p81-2)History of MedicineHistoriography: The writing of history; the principles, theory, and history of historical writing; the product of historical writing. (Webster, 3d ed)Emigration and Immigration: The process of leaving one's country to establish residence in a foreign country.Population Growth: Increase, over a specific period of time, in the number of individuals living in a country or region.Emigrants and Immigrants: People who leave their place of residence in one country and settle in a different country.United StatesTime Factors: Elements of limited time intervals, contributing to particular results or situations.Health Policy: Decisions, usually developed by government policymakers, for determining present and future objectives pertaining to the health care system.Population Dynamics: The pattern of any process, or the interrelationship of phenomena, which affects growth or change within a population.Goiter, Substernal: An enlarged THYROID GLAND with at least 50% of the gland situated behind the STERNUM. It is an unusual presentation of an intrathoracic goiter. Substernal goiters frequently cause compression on the TRACHEA leading to deviation, narrowing, and respiratory symptoms.Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Walking: An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.Heart: The hollow, muscular organ that maintains the circulation of the blood.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Hong Kong: The former British crown colony located off the southeast coast of China, comprised of Hong Kong Island, Kowloon Peninsula, and New Territories. The three sites were ceded to the British by the Chinese respectively in 1841, 1860, and 1898. Hong Kong reverted to China in July 1997. The name represents the Cantonese pronunciation of the Chinese xianggang, fragrant port, from xiang, perfume and gang, port or harbor, with reference to its currents sweetened by fresh water from a river west of it.Agonistic Behavior: Any behavior associated with conflict between two individuals.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Chronology as Topic: The temporal sequence of events that have occurred.Territoriality: Behavior in defense of an area against another individual or individuals primarily of the same species.Orthodontic Brackets: Small metal or ceramic attachments used to fasten an arch wire. These attachments are soldered or welded to an orthodontic band or cemented directly onto the teeth. Bowles brackets, edgewise brackets, multiphase brackets, ribbon arch brackets, twin-wire brackets, and universal brackets are all types of orthodontic brackets.Azores: A group of nine islands and several islets belonging to Portugal in the north Atlantic Ocean off the coast of Portugal. The islands are named after the acores, the Portuguese for goshawks, living there in abundance. (Webster's New Geographical Dictionary, 1988, p102 & Room, Brewer's Dictionary of Names, 1992, p42)Obesity: A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.Multiphasic Screening: The simultaneous use of multiple laboratory procedures for the detection of various diseases. These are usually performed on groups of people.Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.Child Development Disorders, Pervasive: Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.PubMed: A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)Periodicals as Topic: A publication issued at stated, more or less regular, intervals.BooksPublishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.MEDLINE: The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).Social Sciences: Disciplines concerned with the interrelationships of individuals in a social environment including social organizations and institutions. Includes Sociology and Anthropology.Suicide: The act of killing oneself.Masculinity: Male-associated sex-specific social roles and behaviors unrelated to biologic function.Suicide, Attempted: The unsuccessful attempt to kill oneself.Telefacsimile: A telecommunication system combining the transmission of a document scanned at a transmitter, its reconstruction at a receiving station, and its duplication there by a copier.Journalism, Medical: The collection, writing, and editing of current interest material on topics related to biomedicine for presentation through the mass media, including newspapers, magazines, radio, or television, usually for a public audience such as health care consumers.Newspapers: Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)Sex Factors: Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Athletic Injuries: Injuries incurred during participation in competitive or non-competitive sports.Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.Injury Severity Score: An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Accidents, Traffic: Accidents on streets, roads, and highways involving drivers, passengers, pedestrians, or vehicles. Traffic accidents refer to AUTOMOBILES (passenger cars, buses, and trucks), BICYCLING, and MOTORCYCLES but not OFF-ROAD MOTOR VEHICLES; RAILROADS nor snowmobiles.

Regional survey of femoral neck fractures. (1/47319)

In the South-west Thames Region 2619 patients (2105 women and 514 men) were discharged with a diagnosis of femoral neck fracture in 1974. The equivalent of a 250-bedded hospital was occupied throughout the year. The incidence, average length of stay, and mortality rate rose with increasing age and there were differences in these indices in the five health areas. These results confirm the enormous burden placed on the hospital service by patients with fracture of the femoral neck but suggest that differences in practice in the five areas may contribute to the size of the problem.  (+info)

Investigation of maturation requirements for Ostertagia ostertagi and Cooperia oncophora larvae. (2/47319)

Infection of parasite-free six to eight week old calves with doses of 50,000 mixed Ostertagia ostertagi and Cooperia oncophora larvae varying in age from seven to 42 days did not reveal a significant larval maturation requirement.  (+info)

Methoxyflurane nephropathy. (3/47319)

Investigations of methoxyflurane-induced nephrotoxicity in man have been extensively aided by the use of an animal model. To be of value the animal model must share similar metabolic pathways with man and have the same clinical manifestations of the diseases process. The Fischer 344 rat appears to meet these criteria. The predominant factors in the production of methoxyflurane nephrotoxicity appear to be high methoxyflurane dosage and serum inorganic fluoride concentration. It is likely that secondary factors include: (1) a high rate of methoxyflurane metabolism and sepsitivity of the kidney to inorganic fluoride toxicity: (2) concurrent treatment with other nephrotoxic drugs; (3) preexisting renal disease; (4) surgery of the urogenital tract, aorta, or renal vasculative; (5) repeat administration of methoxyflurane due to accumulation of inorganic fluoride and, perhaps, methoxyflurane induction of its own metabolism: and (6) concurrent treatment with enzyme-inducing drugs such as phenobarbital.  (+info)

Determination of human body burden baseline date of platinum through autopsy tissue analysis. (4/47319)

Results of analysis for platinum in 97 autopsy sets are presented. Analysis was performed by a specially developed emission spectrochemical method. Almost half of the individuals studied were found to have detectable platinum in one or more tissue samples. Platinum was found to be deposited in 13 of 21 tissue types investigated. Surprisingly high values were observed in subcutaneous fat, previously not considered to be a target site for platinum deposition. These data will serve as a human tissue platinum burden baseline in EPA's Catalyst Research Program.  (+info)

VEGF is required for growth and survival in neonatal mice. (5/47319)

We employed two independent approaches to inactivate the angiogenic protein VEGF in newborn mice: inducible, Cre-loxP- mediated gene targeting, or administration of mFlt(1-3)-IgG, a soluble VEGF receptor chimeric protein. Partial inhibition of VEGF achieved by inducible gene targeting resulted in increased mortality, stunted body growth and impaired organ development, most notably of the liver. Administration of mFlt(1-3)-IgG, which achieves a higher degree of VEGF inhibition, resulted in nearly complete growth arrest and lethality. Ultrastructural analysis documented alterations in endothelial and other cell types. Histological and biochemical changes consistent with liver and renal failure were observed. Endothelial cells isolated from the liver of mFlt(1-3)-IgG-treated neonates demonstrated an increased apoptotic index, indicating that VEGF is required not only for proliferation but also for survival of endothelial cells. However, such treatment resulted in less significant alterations as the animal matured, and the dependence on VEGF was eventually lost some time after the fourth postnatal week. Administration of mFlt(1-3)-IgG to juvenile mice failed to induce apoptosis in liver endothelial cells. Thus, VEGF is essential for growth and survival in early postnatal life. However, in the fully developed animal, VEGF is likely to be involved primarily in active angiogenesis processes such as corpus luteum development.  (+info)

Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. (6/47319)

Bcl-2 is known to inhibit apoptosis and is thought to play a role in colorectal tumour development. Studies of the promoter region of bcl-2 have indicated the presence of a p53 responsive element which downregulates bcl-2 expression. Since p53 is commonly mutated in colorectal cancers, but rarely in those tumours showing microsatellite instability (MSI), the aim of this study was to examine the relationship of bcl-2 protein expression to MSI, as well as to other clinicopathological and molecular variables, in colorectal adenocarcinomas. Expression of bcl-2 was analysed by immunohistochemistry in 71 colorectal cancers which had been previously assigned to three classes depending upon their levels of MSI. MSI-high tumours demonstrated instability in three or more of six microsatellite markers tested, MSI-low tumours in one or two of six, and MSI-null in none of six. Bcl-2 expression in tumours was quantified independently by two pathologists and assigned to one of five categories, with respect to the number of cells which showed positive staining: 0, up to 5%; 1, 6-25%; 2, 26-50%; 3, 51-75%; and 4, > or =76%. Bcl-2 negative tumours were defined as those with a score of 0. Bcl-2 protein expression was tested for association with clinicopathological stage, differentiation level, tumour site, age, sex, survival, evidence of p53 inactivation and MSI level. A significant association was found between bcl-2 expression and patient survival (P = 0.012, Gehan Wilcoxon test). Further, a significant reciprocal relationship was found between bcl-2 expression and the presence of MSI (P = 0.012, Wilcoxon rank sum test). We conclude that bcl-2 expressing colorectal cancers are more likely to be MSI-null, and to be associated with improved patient survival.  (+info)

Accelerated accumulation of somatic mutations in mice deficient in the nucleotide excision repair gene XPA. (7/47319)

Inheritable mutations in nucleotide excision repair (NER) genes cause cancer-prone human disorders, such as xeroderma pigmentosum, which are also characterized by symptoms of accelerated ageing. To study the impact of NER deficiency on mutation accumulation in vivo, mutant frequencies have been determined in liver and brain of 2-16 month old NER deficient XPA-/-, lacZ hybrid mice. While mutant frequencies in liver of 2-month old XPA-/-, lacZ mice were comparable to XPA+/-, lacZ and the lacZ parental strain animals, by 4 months of age mutant frequencies in the XPA-deficient mice were significantly increased by a factor of two and increased further until the age of 16 months. In brain, mutant frequencies were not found to increase with age. These results show that a deficiency in the NER gene XPA causes an accelerated accumulation of somatic mutations in liver but not in brain. This is in keeping with a higher incidence of spontaneous liver tumors reported earlier for XPA-/- mice after about 15 months of age.  (+info)

Dietary intake and practices in the Hong Kong Chinese population. (8/47319)

OBJECTIVES: To examine dietary intake and practices of the adult Hong Kong Chinese population to provide a basis for future public health recommendations with regard to prevention of certain chronic diseases such as cardiovascular disease, hypertension, and osteoporosis. PARTICIPANTS: Age and sex stratified random sample of the Hong Kong Chinese population aged 25 to 74 years (500 men, 510 women). METHOD: A food frequency method over a one week period was used for nutrient quantification, and a separate questionnaire was used for assessment of dietary habits. Information was obtained by interview. RESULTS: Men had higher intakes of energy and higher nutrient density of vitamin D, monounsaturated fatty acids and cholesterol, but lower nutrient density of protein, many vitamins, calcium, iron, copper, and polyunsaturated fatty acids. There was an age related decrease in energy intake and other nutrients except for vitamin C, sodium, potassium, and percentage of total calorie from carbohydrate, which all increased with age. Approximately 50% of the population had a cholesterol intake of < or = 300 mg; 60% had a fat intake < or = 30% of total energy; and 85% had a percentage of energy from saturated fats < or = 10%; criteria considered desirable for cardiovascular health. Seventy eight per cent of the population had sodium intake values in the range shown to be associated with the age related rise in blood pressure with age. Mean calcium intake was lower than the FAO/WHO recommendations. The awareness of the value of wholemeal bread and polyunsaturated fat spreads was lower in this population compared with that in Australia. There was a marked difference in types of cooking oil compared with Singaporeans, the latter using more coconut/palm/mixed vegetable oils. CONCLUSION: Although the current intake pattern for cardiovascular health for fat, saturated fatty acid, and cholesterol fall within the recommended range for over 50% of the population, follow up surveys to monitor the pattern would be needed. Decreasing salt consumption, increasing calcium intake, and increasing the awareness of the health value of fibre may all be beneficial in the context of chronic disease prevention.  (+info)

Appropriate self-care has an important role in improving the life level of diabetics and it has been proven that perceived barriers is one of the most contributory factors on the success self-carein diabetes. Thus, this study aimed to develop a scale for evaluating perceived barriers for self-care in middle-aged patients with ...
Guys, how much does age affect you with an older girl? Guy is 23 girl in question 26 three years older... what are your thoughts if you have similar interest would it bother you?... asked under Dating
Objective The purpose of this randomized, single-center study was to clarify the impact of anesthetic regimens for laparoscopic myomectomy on the re..
Illustration Works/Getty Images). The rich arent just getting richer, but wealthy older Americans are noticeably better-off than their counterparts from three decades ago in several areas like income, employment, home ownership and housing values.. It may be no surprise that older Americans are wealthier than younger ones. But a new study from Pew Research Center analyzed the economic well-being of current older and younger adults to those in the past and found that the age-based wealth gap skyrocketed 47:1 in 2009 compared to 10:1 in 1984.. In 2009, the median net worth of households headed by adults aged 65 and older was 42 percent more than the same age group in 1984. In contrast, the net worth of households headed by an adult under 35 in 2009 was 68 percent less than the same age group in 1984.. "These age-based gaps widened significantly during the sour economy of recent years, but all key trends are several decades old, indicating that they are also linked to long-term demographic, social ...
Age Specific Animal Toys for 4 Year Olds | Fun learning Animal Toys | ebeanstalk provides 4 Year Olds the best selection of toys, books and games
Age Specific Animal Toys for 4 Year Olds | Fun learning Animal Toys | ebeanstalk provides 4 Year Olds the best selection of toys, books and games
The Samfund is a not-for-profit organization dedicated to easing the lasting financial effects of cancer treatments for young adults with the disease.
Downloadable! This paper proposes the use of optimal grouping methods for determining the various age groups within a population. The cutoff ages for these groups, such as the age from which an individual is considered to be an older person, are then endogenous variables that depend on the entire population age distribution at any given moment. This method is first applied to the age distribution of the United States and subsequently to a group of 12 industrialized countries. The cutoff ages as well as the main indicators of aging are calculated.
The Only Smart People May Pass trope as used in popular culture. This refers to any barrier that requires the heroes to solve some kind of puzzle, Riddle or …
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Age-specific Rate is per 100,000 population in a specific age group. Adding and subtracting the number shown after the ± symbol from the rate creates a confidence interval indicating that the true rate lies between the lower and upper bounds of this interval with 95% statistical confidence ...
Age-specific Rate is per 100,000 population in a specific age group. Adding and subtracting the number shown after the ± symbol from the rate creates a confidence interval indicating that the true rate lies between the lower and upper bounds of this interval with 95% statistical confidence ...
Cardiovascular diseases amount for up to 7 lakh deaths in America per year. Taking care to prevent heart attacks and strokes becomes the immediate issue to look after, especially after it has been increasing at an alarming rate and has victimized people from various age groups. Heart diseases are caused due to increased risks of stress and depression, smoking and alcohol consumption, and consumption of food which has high amount of cholesterols, especially junk food ...
Three ICSS standards used to calculate age-standardized survival for cancer sites in adults. Plus age variables and population weights for each standard.
Age difference does not need to be a primary concern in your relationship, if you have mutual interests and friends, and you are able to discuss your uncertainties in a frank and honest manner. As...
Theres chronological age and performance age and both may not be the same. So what is age? Some maintain age is a physical state, others believe it has
I am still dabbling in on-line dating, although it really isnt going all that well, and I am also going to social groups to widen my circle of friends and meet new people, maybe a new man. I have always thought it is much harder for women to find a man because most men date…
Probably because when treating it as continuous they only look for linear regression.. When categorizing in buckets, they probably do an ANOVA. This technique posits that the average does vary per category exactly as measured, and asks the question: If I tell you the category, how much is the variance of your data reduced? If the variance falls a lot (relatively to what it was), it means theres a statistically significant effect between the category and your variable.. And, in their defense, they cant really go fishing for different continuous relationships once they have the data, as thatd reduce their statistical power.. Of interest too is the number of adjustable parameters of the model:. If instead of four age categories you use, say, four hundred, you end up splitting each doctor into one category. The predictive power of that model is greatest, with very good statistical significance, but you have achieved no insight at all.. Similarly when taking age as continuous; if instead of a ...
When a very old patient is admitted to the ICU, we note that age is a risk factor for poor outcomes from virtually every disease. However, reaching an advanced age also says something about the characteristics of the patient, which we may forget.. It is a truism that upon reaching middle age or thereabouts, most patients stop behaving like their calendar age, medically speaking, and start to instead resemble their state of health. There are 50-year-olds who look 100, and 90-year-olds who look 70. We understand this, and when we admit a 60-year-old man with chronic diseases of multiple organs, we acknowledge they have nothing in common with a person of the same age who still runs marathons. Indeed, most of those comorbid individuals do not survive to extreme old age; there are not many 90-year-olds with uncontrolled diabetes, CHF, renal failure, and so on.. Consider the consequences of this. In many ways, very elderly patients (over 85, say-certainly in their 90s and above) are the healthiest ...
Remember that study where scientists put blood from young mice into old mice and it reversed aging? Research has begun on humans.
Nutrition is a part of science that studies, as well as analyzes and interprets, the relational effect of nutrient in food and other food substances to the growth, life and health maintenance, reproduction, and diseases of people and also of living organisms. This includes the food intake, absorption and assimilation, biosynthesis, catabolism and excretion. The…
With over one million drivers over the age of 80 in the UK (and 122 centenarians), why does age still affect the cost of car insurance - for young and old?
Young children are better able to reason about concrete things and their cognitive systems are eager to absorb general facts, which are taught to them.
Is it possible that some day there will be clinics open to treat people for having an addiction to Oreos? Will nurses hand out plastic cups that have little second-rate versions of the cookie to tide a person over until they can ... ...
Think sex in your 40s is impossible? Hardly-youre just getting warmed up. Heres what to expect when youre getting it on in your fourth decade.
Multisensory & Highly Sensitive People may benefit from codependent recovery in lieu of suffering a manifesting of painful karma which this narrative tells.
Shermers piece, in which he is looking back on his years as a Scientific American columnist, feels like an elegy. The reality today is that, however people may u
We all want to be liked. The desire for approval, appreciation, and acceptance by others is a normal part of being human. And although some people may care less
Bear in mind, people may come to your website wanting to buy your product however at this stage online retailing may not be viable or even possible for you. Thats ok. You dont have to fulfil every desire of every client. Just give them an alternative. Share the information. Tell them where they can buy from, make it easy ...
If youve reached the fourth decade of life, you may have begun to notice vision changes or may have experienced other eye-related issues largely associated
WebMD provides important information about Larin Fe 1/20 (28) Oral such as if you can you take Larin Fe 1/20 (28) Oral when you are pregnant or nursing or If Larin Fe 1/20 (28) Oral dangerous for children or adults over 60.
WebMD provides important information about Rectagene Rectal such as if you can you take Rectagene Rectal when you are pregnant or nursing or If Rectagene Rectal dangerous for children or adults over 60.
How to Prevent Falls. As we age, the chances of falling increase and the risks become more severe. One in three adults over the age of 65 will fall this year and the odds increase to one in two by our eighties. Unfortunately for many,...
BACKGROUND: Nearly all studies have suggested that the use of oral contraceptives (OC) is not associated with the aggregate risk of breast cancer diagnosed in women aged 20-54 years. Because of age-specific differences in the breast cancer-parity relationship and because of age-specific differences in other breast cancer risk factors, the Centers for Disease Control reexamined data from the Cancer and Steroid Hormone Study (CASH) to assess whether OC use has different effects on the risk of breast cancer at different ages of diagnosis. METHODS: This population-based case-control study was designed to examine the relationship between the use of OC and the risk of breast, ovarian, and endometrial cancer. CASH was conducted in eight geographic areas in the United States during 1980-1982. All participants were interviewed at home with a pretested standardized questionnaire including a calendar of life events and a photograph book of all pills marketed in the United States. RESULTS: We found that the
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RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) together with steroid therapy may kill more cancer cells.. PURPOSE: This clinical trial is studying the side effects of combination chemotherapy in treating young adult patients with acute lymphoblastic leukemia. ...
We incorporated behavioral and computational modeling techniques to examine age-based differences in strategy use in two four-choice decision-making tasks. Healthy older (aged 60-82 years) and younger adults (aged 18-23 years) performed one of two decision-making tasks that differed in the degree to which rewards for each option depended on the choices made on previous trials. In the choice-independent task rewards for each choice were not affected by the sequence of previous choices that had been made. In contrast, in the choice-dependent task rewards for each option were based on how often each option had been chosen in the past. We compared the fits of a model that assumes the use of a win-stay-lose-shift (WSLS) heuristic to make decisions, to the fits of a reinforcement-learning (RL) model that compared expected reward values for each option to make decisions. Younger adults were best fit by the RL model, while older adults showed significantly more evidence of being best fit by the WSLS heuristic
Most of the couples are able to conceive within two years of unprotected regular sex. If you are not able to conceive even in two years, this is the case of infertility. In this case, it is necessary to consult some doctor or take some necessary steps that are required for getting pregnant.
Background: Acute lung injury (ALI) is a significant source of morbidity and mortality in critically ill patients. Age is a major determinant of clinical outcome in ALI. The increased ALI-associated mortality in the older population suggests that there are age-dependent alterations in the responses to pulmonary challenge. The objective of this observational study was to evaluate age-dependent differences in the acute (within 6 hours) immunological and physiological responses of the heart and lung, to pulmonary challenge, that could result in increased severity. Methods: Male C57Bl/6 mice (young: 2-3 months, old: 18-20 months) were challenged intratracheally with cell wall components from Gram-positive bacteria (lipoteichoic acid and peptidoglycan). After 6 hours, both biochemical and physiological consequences of the challenge were assessed. Alveolar infiltration of inflammatory cells and protein, airspace and blood cytokines, cardiac function and myocardial proteasome activity were determined. Results:
Discussion. The results showed that the most hypertension occurred at the age of 60-69 years, followed by elderly aged 70 years with a percentage of 32.4%. This age belongs to the elderly group, and the elderly group is at high risk. The age factor is one of the factors that play an important role in the incidence of hypertension. The older the people, the more changes in physical and biological. Changes that occur are part of the vulnerability, which becomes one of the predisposing factors for health status that becomes worse.8 The findings showed that many elderly people aged 60-69 years do an unbalanced lifestyle and still consume a lot of fat intake such as fried foods. Most of the elderly in the health center area highlighted that consuming fried foods have become a habit that cannot be avoided. Elderly have a habit of consuming excess fat, fast food, fatty foods and high cholesterol.9. Women have the largest proportion with the incidence of hypertension as many as 79 people (73.1%). This ...
Although one person may be diagnosed with more than one tumour, their death is only counted once in these statistics. The ONS rules around coding death certificates are used to determine which tumour is the cause of death in these cases. Some patients with cancer die for reasons not related to their cancer. These are not included in the mortality statistics.. Standardised rates are standardised according to an approximate 2013 European Standard Population. The five year age bands in the ESP are grouped into the age bands published on this tool to make a standard population for these age bands. Data presented are taken from the ONS Mortality Extract provided to the National Cancer Registration Service aligned with DR 2017.. ...
This study examined stopping and performance adjustments in four age groups (M ages: 8, 12, 21, and 76 years). All participants performed on three tasks, a standard two-choice task and the same task in which stop-signal trials were inserted requiring either the suppression of the response activated by the choice stimulus (global stop task) or the suppression of the response when one stop signal was presented but not when the other stop signal occurred (selective stop task). The results showed that global stopping was faster than selective stopping in all age groups. Global stopping matured more rapidly than selective stopping. The developmental gain in stopping was considerably more pronounced compared to the loss observed during senescence. All age groups slowed the response on trials without a stop signal in the stop task compared to trials in the choice task, the elderly in particular. In addition, all age groups slowed on trials following stop-signal trials, except the elderly who did not slow
Nice study that examines the relationship between with decreased ovarian reserve and age at menarche. The authors conclude that women with younger age at menarche are more likely to have lower age specific AMH levels. However, several other authors have published papers recently addressing this question with conflicting results ...
The increasing incidence of and interest in hepatitis in the last decade is clearly discernible from the constantly rising volume of literature on the subject. In the past several years we have encountered numerous cases of jaundice in various age groups in which the correct diagnosis became apparent after a brief survey, including various laboratory procedures in conjunction with a short period of clinical observation. In several cases, however, the history and the laboratory studies left the clinical picture sufficiently confused as to necessitate more involved diagnostic procedures, such as cholangiography, liver biopsy and even exploratory laparotomy.. These patients presented ...
An experiment was conducted to examine the effect of age on heart rate when an individual is subjected to a specific amount of exercise. Ten male subjects were randomly selected from four age groups: 10-19, 20-39, 40-59, and.
Four images, two girls - and a story. Its all in the mind; think about it. It was a hot day, the grass was very dry and they were both very thirsty, but Joanne and her small group had walked the pair all the way over to where the big, old, wooden... ...
The low number of incorrect identifications, combined with the absence of any correct ones probably means that the risk in the dataset is low enough to be considered suitable for "open data". However, it might even be deemed too cautious with disclosure control being applied too strictly. The ideal situation is to have a fair number of incorrect identifications and very few (not necessarily nil) correct identifications. For this example it was decided to reattempt intruder testing, but to use eight age bands instead of four age bands; results are shown in Table A5.. The question is then one of risk appetite. The level of risk that one would normally take with an open dataset (and therefore to be publicly available) is usually very low. Always remember that it would be perfectly legal for an intruder or researcher to attempt to identify an individual and to claim to have made a correct identification. It is therefore important for a data provider to have a strategy in place for that instance. ...
Its not the age bands, writes Harold. Hes right. It isnt. I have no disagreement with what Harold wrote. However, I may be more open to additional
본 연구는 연령이 증가함에 따라 나타나는 지방대사의 변화에 대하여 식이내 단백질수준이 어떻게 영향을 미치는가를 관찰하고저 행하여졌다. 실험동물은 평균체중이 70.4±2.4g (생후 4주)과 287.1±6.3g(생후 5~6개월)인 Wistar종 수컷 흰쥐 48마리를 연령에 따라 어린군(Young Group)과 성숙한 군(Adult Group)으로 나누었고 각 연령군을 7%, 15%, 50%로 단백질 수준을 각각 달리하여 5주간 사육하였다. 본 실험의 결과들을 요약해 보면 다음과 같다. 체중 100g당 식이 섭취량과 단백질 효율은 연령의 차이없이 7% 단백질군이 50%단백질군에 비해 유의적으로 높았고 체중 증가량은 두 연령군 모두 50% 단백질군에서 가장 높았다. 지방의 흡수율은 성숙한 쥐가 어린쥐보다 약간 낮았고, 단백질수준이 증가할수록 각 연령군 모두에서 낮아졌다. 혈청내 총지방량, 총콜레스테롤 및 ...
Matsuzawa, T and Cinader, B, "Polymorphism of age-dependent changes in the production of a thf helper factor." (1982). Subject Strain Bibliography 1982. 2609 ...
Age of first sexual intercourse[edit]. One study has several factors that influence the age of first sexual intercourse among ... Research shows that the age of US rape victims correlates slightly better with age of peak fertility than age of peak ... The age and status difference between the men involved, suggests that a dominance-submission dynamic was an important factor in ... 1 Factors influencing male sexual behaviour *1.1 Age of first sexual intercourse ...
Demographic and cultural factors[edit]. Age of voters[edit]. It has been argued that the result was caused by differential ... Presentational factors during the campaign[edit]. Misleading information[edit]. A "Vote Leave" poster in Omagh saying "We send ... According to Opinium, 64% of eligible people aged 18-24 voted, whereas 90% of eligible individuals over 65 voted.[20] It is ... Boris Johnson and cabinet minister Michael Gove became leading figures in the Leave Campaign is a factor considered to have ...
Age factor[edit]. In children, the outcome of distal radius fracture is usually very good with healing and return to normal ... Incidences in females outnumber incidences in males by a factor of three to two. Average age of occurrence is between 57 and 66 ... Indications for each depend on a variety of factors such as the patient's age, initial fracture displacement, and metaphyseal ... Ulnar styloid process fracture increases the risk of TFCC injury by a factor of 5:1. However, it is unclear whether intercarpal ...
2 Demographic factors *2.1 Age. *2.2 Sex. *2.3 Ethnicity and culture. *2.4 Marital status ... For every 100,000 individuals within an age group there are 0.9 suicides in ages 10-14, 6.9 among ages 15-19, and 12.7 among ... Age[edit]. In the United States, the peak age for suicide is early adulthood, with a smaller peak of incidence in the elderly.[ ... Fawcett J (2007). "Chapter 4. Acute risk factors for suicide: anxiety severity as a treatment modifiable risk factor". In ...
Non-modifiable risk factors of diabetic complications are type of diabetes, age of onset, and genetic factors, both protective ... Risk factors[edit]. Age[edit]. Type 2 diabetes in youth brings a much higher prevalence of complications like diabetic kidney ... risk factors such as age at diabetes onset, type of diabetes, gender and genetics play a role. Some genes appear to provide ... April 2011). "Coagulation Factors Evaluation in NIDDM Patients". American Journal of Biochemistry and Molecular Biology. 1 (3 ...
Age factor[edit]. Research suggests that people younger than 40 years also show a reminiscence bump.[23] It was initially ... The younger group (ages 20-42) showed the usual increase in memories during the reminiscence bump while the older group (ages ... 4) the age estimates for negative events had higher standard deviation than age estimates for positive and neutral events, ... If the brain damage was present at the age of 10, the individual may not remember anything from between the age of 10 and 30 ...
Risk factors[edit]. Risk factors associated with gingivitis include the following: *age ...
Exp Aging Res, 2000. 26(2): p. 103-20. Sekuler, R. and K. Ball, Visual localization: age and practice. J Opt Soc Am A, 1986. 3( ... Hum Factors, 1991. 33(5): p. 583-95.; Ball, K., C. Owsley, and M. Sloane, Visual and cognitive predictors of driving problems ... Exp Aging Res, 1991. 17(2): p. 79-80.; Ball, K., et al., Visual attention problems as a predictor of vehicle crashes in older ... Aging Ment Health, 2005. 9(3): p. 262-71.; Edwards, J.D., et al., Transfer of a speed of processing intervention to near and ...
This was the apex of the age of heroic exploration. Additionally, there was the factor of the telegraph. Invented only a few ... Several factors contributed. At "home" (as Australians still called Britain), public attention was focussed on the search for ... He graduated from the Scottish Naval and Military Academy as a civil engineer before emigrating to Australia at the age of 23. ... Members of Stuart's 1861-1862 expedition party The ten successful members of the party are listed here with their age on the ...
Tzivion G, Dobson M, Ramakrishnan G (November 2011). "FoxO transcription factors; Regulation by AKT and 14-3-3 proteins". ... Aging Cell. 10 (4): 622-8. doi:10.1111/j.1474-9726.2011.00698.x. PMID 21388494. ... a novel member of the FoxO class of transcription factors with distinct shuttling dynamics". The Journal of Biological ...
Fin de siècle Gilded Age Information Age "Chicago Style Q&A: Numbers". The Chicago Manual of Style Online. Retrieved 2011-01-11 ... Salas, E (1 June 2008). "At the turn of the 21st century: reflections on our science". Human Factors. 50 (3): 351-353. ...
Key success factors: • Bedding - Selection of proper bedding material like paddy straw, sugarcane baggasse or coconut coirs is ... It can be practiced by people of all ages. The derived Vermicompost and vermiwash can be used to create small balcony plants, ...
Risk factors[edit]. *Advanced age. *constipation. *a diet that is low in dietary fiber (although this claim is controversial) ... Approximately 50% of people over the age of 60 and 70% of people over the age of 80 have diverticulosis.[1] This disease is ... Diverticula are uncommon before the age of 40, and increase in incidence beyond that age.[5] Rates are lower in Africa which ... It is common in Western countries with about half of those over the age of 60 in Canada and the United States affected.[4] ...
Risk factors[edit]. Hypertension, or abnormally high blood pressure, often signifies an elevated level of both psychological ... Increased age. *Abnormal body height. *History of cardiovascular disease (CV). *Abnormal ANP levels ... Additional factors that may contribute to spontaneous premature atrial contractions could be:[4] ... "Atrial fibrillation: hypertension as a causative agent, risk factor for complications, and potential therapeutic target". The ...
... generation of proinflammatory factors; premature aging; prooxidant and antioxidant alterations that lead to cellular damage; ...
Among other factors that may impede the healing of a wound are: patient's age obesity presence of infection poor nutrition or ... Wound assessment is a holistic process that considers the patient's current state of health, the factors that may impede wound ... Anderson, K; Hamm, R (December 2012). "Factors That Impair Wound Healing". Advances in Wound Care. 4 (4). doi:10.1016/j.jccw. ... Gosain, A; Dipietro, L (March 2004). "Aging and wound healing". World Journal of Surgery. 28 (3). doi:10.1007/s00268-003-7397-6 ...
It becomes more common with age. Pain in the heel, usually on the middle of the heel. This is in direct contrast to plantar ... Risk factors include obesity. Other conditions with similar symptoms include plantar fasciitis. Treatment includes rest, pain ...
Demographic changes; for example, baby boomers drive less as they age, according to one view. Economic factors, particularly ... Factors include: Travel time budgets, a theoretical psychological limit suggesting a long term constraint on the amount of time ... Factors affecting land travel". Transport Policy. ! (1): 1-22. Schipper, Lee (2011). "Automobile use, fuel economy and CO2 ... However, a contrasting view suggested that e-commerce was not a substantial factor explaining less car travel in the United ...
... a critical growth factor involved in normal mammary gland development. In addition, agonists of the epidermal growth factor ... For example, in a study of aged female rhesus macaques, treatment with GH alone, IGF-1 alone, and the combination of GH and IGF ... This could be related to increased synergy of estrogens with the higher levels of GH/IGF-1 that are present with younger age. ... Kleinberg DL, Wood TL, Furth PA, Lee AV (2009). "Growth hormone and insulin-like growth factor-I in the transition from normal ...
Risk factors[edit]. Acquired[edit]. *Older age[7]. *Major surgery, orthopedic surgery,[8] neurosurgery[9] ... ratio of 4.3 among male individuals 20 to 29 years of age and 5.5 among female individuals 10 to 19 years of age).[24] ... 2012). "Elevated factor VIII levels and risk of venous thrombosis". Br J Haematol. 157 (6): 653-63. doi:10.1111/j.1365- ... Adjusted for age and calendar year. † = Unadjusted ratio calculated based on the data provided. Source: [25] ...
Risk factors[edit]. Acquired[edit]. *Older age[5]. *Major surgery and orthopedic surgery[6] ... The factor V protein is mutated in carriers of factor V Leiden, which is the most common inherited DVT risk factor.[16] ... ratio of 4.3 among male individuals 20 to 29 years of age and 5.5 among female individuals 10 to 19 years of age).[20] ... 2012). "Elevated factor VIII levels and risk of venous thrombosis". Br J Haematol. 157 (6): 653-63. doi:10.1111/j.1365- ...
Other factors that can affect a woman's chances of conceiving include being overweight or underweight,[54] or her age as female ... small for gestational age (SGA) babies, low birthweight (LBW) babies or preterm deliveries, must be factored. (...) However, ... For women aged 38, however, only about 77%. The effect of age upon men's fertility is less clear.[68] ... General factors *Diabetes mellitus,[35][36] thyroid disorders,[37] undiagnosed and untreated coeliac disease,[38][39][40][41] ...
In people over age 50, the body's thirst sensation diminishes and continues diminishing with age. Many senior citizens suffer ... Risk factors for dehydration include but are not limited to: exerting oneself in hot and humid weather, habitation at high ... "Dehydration Risk factors - Mayo Clinic". www.mayoclinic.org. Retrieved 2015-12-14. Borra SI, Beredo R, Kleinfeld M (Mar 1995 ... "Hypernatremia in the aging: causes, manifestations, and outcome". J Natl Med Assoc. 87 (3): 220-4. PMC 2607819 . PMID 7731073. ...
Other factors are age of 70 years and older, current smoking history, dry skin, low body mass index, urinary and fecal ... There are over 100 risk factors for pressure ulcers. Factors that may place a patient at risk include immobility, diabetes ... These factors are protein-calorie malnutrition, microclimate (skin wetness caused by sweating or incontinence), diseases that ... It is widely believed that other factors can influence the tolerance of skin for pressure and shear, thereby increasing the ...
Aging. 3 (9): 821-8. doi:10.18632/aging.100380. PMC 3227447 . PMID 21931183. Mattson, M (2008). "Dietary Factors, Hormesis and ... "Can We Prevent Aging?". National Institute on Aging, US National Institutes of Health, Bethesda, MD. 29 July 2016. Archived ... Cava E, Fontana L (2013). "Will calorie restriction work in humans?". Aging. 5 (7): 507-14. doi:10.18632/aging.100581. PMC ... older age, higher diet quality, and female sex were positive factors affecting the benefits realized from lower caloric intake ...
Neurobiol Aging. 34 (12): 2815-26. doi:10.1016/j.neurobiolaging.2013.06.015.. CS1 maint: Multiple names: authors list (link) ... from growth factors to hormones that modulate and influence the growth and development of functional connections between ...
In fact, the aging process is the biggest risk factor for breast cancer. Thats because the longer we live, there are more ... While you cant stop the aging process, you can make lifestyle choices that can keep your risk as low as it can be:. * ... And as we age, our bodies are less capable of repairing genetic damage. ...
Study Title: Age-Specific Risk Factors for Advanced Stage Colorectal Cancer, 1981-2013. CME Questions. *You are seeing a 45- ... Suggested citation for this article: Moore KJ, Sussman DA, Koru-Sengul T. Age-Specific Risk Factors for Advanced Stage ... We identified significant age-specific risk factors for advanced stage CRC presentation. With CRC incidence on the rise among ... Multivariable logistic regression models for all patients and by age group were fitted to identify risk factors for advanced ...
... though there are a variety of other risk factors and pre-existing conditions that could increase susceptibility. ... However, there are other factors that patients claim could be a potential cause or influencing factor to their malignant ... Mesothelioma Causes & Risk Factors. Mesothelioma is a rare and deadly cancer caused by the inhalation of asbestos fibers. When ... Age: Elderly and Mesothelioma. One common misconception of mesothelioma is that it occurs only in the elderly. 91% of those ...
It was the oldest shuttle in an old fleet. But as NASA tries to sort out what caused Columbia to disintegrate over Texas, experts said it was no more troublesome than any other of the complex spacecraft. Dennis R. Jenkins, a former shuttle engineer and historian of the program, said: There were a lot of early issues, but she was the first vehicle and she got repaired. Some of the issues included a tendency for the ceramic heat tiles to fall off the shuttle's skin.
Texas law does not allow us to presume incapacity only because of age. The jury thought that the brokers actions were ... premack/article/Prepare-before-age-and-infirmity-become-factors-11197555.php ... Still, both age and infirmity are conditions that raise legal uncertainties. Actually, Texas law does not allow us to presume ... The Guardian claimed the stockbroker should know, because of Cairns age alone, that she would not understand the transaction. ...
... years of age. Girl fatalities were most common among victims ,6 years of age, and the proportion significantly decreased as age ... Age-Based Risk Factors for Pediatric ATV-Related Fatalities. Gerene M. Denning, Karisa K. Harland, Charles A. Jennissen ... 6 years of age had a significantly lower proportion of helmeted riders than other age groups. This was largely because the age ... Younger age has been identified as an independent risk factor for all-terrain vehicle (ATV)-related injuries. Since the mid- ...
Patients with age-related macular degeneration, or AMD, progressively lose their central vision and find it harder to see ... Risk factors. Figures for 2010 showed that in the United States, AMD affected 2.1 percent of people aged over 40 years. Among ... According to the American Academy of Ophthalmology (AAO), key factors that appear to play a role include:. Age: The risk ... Other factors may include:. * Dietary fat: Studies indicate that those who consume a lot of saturated fats are more at risk of ...
... stroke and aging that is also a positive regulatory element in neuronal development. Whereas in all the... ... Perez-Polo J.R. (1990) Role of Trophic Factors in Neuronal Aging. In: Lauder J.M., Privat A., Giacobini E., Timiras P.S., ... Perez-Polo, J.R., Apffel, L., Werrbach-Perez, K., 1986, Role of CNS and PNS trophic factors on free radical mediated aging ... Agranoff, B.W., 1984, Lipid peroxidation and membrane aging. Neurobiol. of Aging, 5: 337-338.CrossRefGoogle Scholar ...
Aging, i.e. a decline in the growth rate of the native population, has an expansionary effect on immigration. This immigration ... In this note we analyze how aging affects immigration policy. We set up a dynamic political-economy model of representative ... "Aging, Factor Returns, and Immigration Policy," Scottish Journal of Political Economy, Scottish Economic Society, vol. 58(5), ... "Demographics and Factor Flows - A Political Economy Approach," Ruhr Economic Papers 299, RWI - Leibniz-Institut für ...
Sex, age and shock-intensity as factors in passive avoidance.. Van Oyen HG, Van De Poll NE, De Bruin JP. ... Sex, age and shock-intensity were studied in a step-through passive avoidance test. In adult rats (140 days) males showed more ...
... and demographic factors acting throughout life, analysis of data from a nested case-control study show ... Change in lung function between youth and middle age is influenced by multiple physical, medical, ... Analysis of this sample revealed that factors predicting lower FEV1 at age 14 included: *Childhood history of severe ... Regression analysis identified these factors as predictive of a greater decline (or a smaller increase) in FEV1 between ages 14 ...
... some risk factors put young women at a higher risk for getting breast cancer at a young age. ... In addition to the risk factors all women face, ... Risk Factors for Breast Cancer at a Young Age. ... One in 10 women diagnosed with breast cancer are under the age of 45. Learn about the risk factors for early onset breast ... In addition to the risk factors all women face, some risk factors put young women at a higher risk for getting breast cancer at ...
... obviously in response to speculation that Republicans can take advantage of HRCs relatively advanced age (she would be, if ... Geoffrey Skelley of Larry Sabatos Crystal Ball has some interesting data on age as a factor in presidential elections, ... Geoffrey Skelley of Larry Sabatos Crystal Ball has some interesting data on age as a factor in presidential elections, ... This factor might be strengthened if her opponent is a much younger man who is perceived as not having yet paid his dues. After ...
The confirmed maternal risk factors include short stature, low weight, Indian or Asian ethnicity, nulliparity, mother born SGA ... There are many established risk factors for babies who are small for gestational age (SGA) by population birth weight centiles ... Risk factors for small for gestational age infants Best Pract Res Clin Obstet Gynaecol. 2009 Dec;23(6):779-93. doi: 10.1016/j. ... There are many established risk factors for babies who are small for gestational age (SGA) by population birth weight centiles ...
After adjusting for other factors that may influence risk, including smoking, age, sex and vitamin C intake, those in the group ... Of the 681 men, 222 (average age 75.9 years) had intermediate or late-stage AMD and 459 (average age 74.5 years) had no AMD or ... Age-related macular degeneration (AMD) occurs when the macula, the area at the back of the retina that produces the sharpest ... "Age-related macular degeneration is a common eye disease in older persons, smoking is a common avoidable behavior and dietary ...
Learn more about the age of onset for type 2 diabetes. Discover the diabetes risk factors for adults, teens, and children. Also ... Risk factors affecting children. For people under the age of 18, testing for diabetes should occur if the child is greater than ... In 2015, adults aged 45 to 64 were the most diagnosed age group for diabetes. New cases of both type 1 and type 2 diabetes in ... Age at the time of diagnosis. Middle-aged and older adults are still at the highest risk for developing type 2 diabetes. ...
... grandparent and dad with CAD at age 55. They both were smoking and had high chol. + blood pressure. Had my most recent stress ...
... and secure a hat-trick of Hong Kong titles at the age of 48 years and 318 days. ...
The brains of middle-age adults may be aging prematurely if they have obesity or other factors linked to cardiovascular disease ... The brains of middle-age adults may be aging prematurely if they have obesity or other factors linked to cardiovascular disease ... home/alzheimers center/ alzheimers a-z list/ obesity, other factors speed up brain aging article ... "With the aging of the U.S. population," Wylie-Rosett said, "could a campaign to promote healthy eating and physical activity ...
Many older adults have sleep problems that can be caused by aging. But other issues contribute to the prevalence of sleep ... Many people experience a circadian rhythm shift as they age, such that they awaken earlier in the morning and do not feel they ... Many older adults have sleep problems that can be caused by aging. But other issues contribute to the prevalence of sleep ... Later in life, there also tend to be other factors that undermine good sleep quality, Neubauer said. ...
Factors associated with age of diagnosis among children with autism spectrum disorders.. Mandell DS1, Novak MM, Zubritsky CD. ... The average age of diagnosis increased 0.2 years for each year of age. Rural children received a diagnosis 0.4 years later than ... Factors Associated With Age of Diagnosis Among Children With Autism Spectrum Disorders ... Few studies have identified factors that may delay diagnosis. This study attempted to identify these factors among a community ...
Number Of Factors Raising Suicide Risk In Middle-Aged Men. by editor ... Researchers in the UK are suggesting that suicide rates among middle-aged males are climbing after years of dropping off. ... The report further found that rapid social change has left middle aged men as a "buffer generation", caught between the "stiff- ... Rory O´Connor, professor from the University of Stirling, suggested the shift could be partially explained by an aging ...
Understanding the differences among drivers in different gender and age categories is crucial to preventing serious injuries, ... Age, Gender Major Factors in Severity of Auto-Accident Injuries. by VR Sreeraman on January 6, 2007 at 8:33 PM General Health ... "Because the factors that affect how severely you are going to be injured vary depending on your age and gender, a better ... "It is reasonably well known that age and gender have an effect on the likelihood of an accident, but the influence that age and ...
So I was wondering if there was an age multiplying factor to apply to these values.. Im heading off to the gym this morning ... Performance Standards and age factor. Ask or answer questions, discuss and express your views. ... I dont know of any formula that would allow you to adjust for age. There are some strength atheletes your age and older who ... I dont dare do the Press or the Clean as I am worried about lower back problems (age, eh?).. The bad news is that I still need ...
The present work takes a first step towards a psycholinguistic investigation on the potential impact of the aging factor on the ... Does the aging factor affect the ability to recover from the discourse mental model information introduced as presupposed? (iii ... Does the aging factor affect the ability of updating the discourse mental model with presupposed information? The Experiment ... notably affected by aging (e.g. Cappell et al., 2010). Finally, the decrease in working memory ability with aging affects older ...
  • On the other hand, if you consume pesticide-ridden foods, regularly apply bath and beauty products that are laced with harmful chemicals, skip out on sleep and meals, don't exercise, poorly manage stress - you are out of sync with nature - with the Tao - you will age you fast and give diseases prime opportunity to strike in your body. (medium.com)
  • This 100-participant landmark clinical study stems from over two decades of molecular, animal, and clinical testing at USC's Valter Longo laboratory under the sponsorship of the National Institute of Aging and the National Cancer Institute of the NIH. (eurekalert.org)
  • Learn about the risk factors for early onset breast cancer and find out what to do if you think you may be at risk. (cdc.gov)
  • Learn what you can do to prevent or delay its onset, no matter your age. (healthline.com)
  • Even among young adults of the same age, on the same program, some will progress faster or slower than predicted (and/or be stronger or weaker at the onset). (exrx.net)
  • After controlling for parental polygenic risk scores, every 10-year delay in paternal age increased the risk of early-onset schizophrenia in offspring by about 30 percent," said lead author Shi-Heng Wang, Ph.D., China Medical University in Taichung. (psychcentral.com)
  • Maternal age was not associated with risk of early onset in offspring. (psychcentral.com)
  • Presumably, advanced paternal age increases risk for early-onset schizophrenia because advancing age is associated with an accumulation of mutations," writes John Krystal, M.D., editor of Biological Psychiatry . (psychcentral.com)
  • It would be important to understand the distinct neural mechanisms through which advanced paternal age influenced the age of onset. (psychcentral.com)
  • The loss or diminution of JPFs after a given stage of postnatal development or at time of sexual maturity may contribute to the onset of deleterious aging changes (e.g., compromised stem cell function and reparative capacity) across adulthood. (nih.gov)
  • However, Parkinson's disease can also be diagnosed in patients who are under the age of 50, in which case it is referred to as young-onset Parkinson's disease. (sharecare.com)
  • In very rare cases, Parkinson's disease can begin before the age of 20, in which case it is referred to as juvenile-onset Parkinson's disease and is usually due to a genetic inheritance. (sharecare.com)
  • The average age of the onset of the disease is 60 years, and the incidence rises significantly with increasing age. (sharecare.com)
  • However, about 5-10 percent of people with Parkinson's disease have an "early-onset" of the disease, which begins before the age of 50. (sharecare.com)
  • Young age at onset, female gender, relapsing/remitting course, and sensitive or visual disturbances as initial symptoms are considered favourable prognostic factors. (biomedsearch.com)
  • Conversely, late age at onset, male gender, progressive course, and pyramidal or cerebellar symptoms at the first episode predict an unfavourable evolution. (biomedsearch.com)
  • Aging, i.e. a decline in the growth rate of the native population, has an expansionary effect on immigration. (repec.org)
  • And total lifetime cigarettes smoked predicted greater decline in FEV 1 between ages 14 and 50 years ( P =0.007), the researchers reported in the January issue of Chest . (medpagetoday.com)
  • However, it has been unclear whether these influences are limited to early life, or whether later factors also contribute to accelerated respiratory decline in middle age. (medpagetoday.com)
  • This subclinical brain aging may precede clinically visible decline, but it's unclear if these findings affect daily functioning," Angoff said. (medicinenet.com)
  • Introduction The language ability is known to decline across the life span and it has been shown that aging in healthy speakers compromises language comprehension in three main aspects: processing speed, inhibition of irrelevant information and working memory (Myerson et al. (frontiersin.org)
  • In the psycholinguistic literature, the decline of language ability with aging has been studied at the syntactic, phonological and semantic level. (frontiersin.org)
  • Dr. Karen Rodrigue is particularly interested in knowing how such health factors as hypertension and diabetes contribute to brain aging and cognitive decline. (utdallas.edu)
  • Rodrigue is particularly interested in knowing how such health factors as hypertension and diabetes contribute to brain aging and cognitive decline, because these conditions are both prevalent in older adults, and amenable to prevention and treatment. (utdallas.edu)
  • The skin is a hormone-dependent organ, and the decline of hormonal secretions during menopause accelerates skin aging. (gcimagazine.com)
  • I get it, there is a lot of information out there about this topic, and although it is true that ovarian reserve (how many eggs you have left in your ovaries) does decline with age, that is not the entire picture. (medium.com)
  • Aging can generally be defined as a progressive decline in the efficiency of biochemical and physiological processes after the reproductive phase of life. (westonaprice.org)
  • Aging , decreased blood flow and diseases like Alzheimer's can lead to a smaller brain. (medicinenet.com)
  • In the current publication, researchers tested the effects of three monthly ProLon cycles on metabolic markers and risk factors associated with aging and age‐related diseases. (eurekalert.org)
  • Rodrigue's focus on the interactions between normal mechanisms of cognitive aging and various diseases that may impact those mechanisms holds great promise for clarifying some of the most complex and least understood patterns of aging, said Dr. Bert Moore, dean of BBS. (utdallas.edu)
  • Most cardiovascular diseases can be prevented by addressing behavioral risk factors, the understanding of these risk factors, their mechanisms and impact on the cardiovascular system. (coursera.org)
  • It has been shown to increase longevity and delay the progression of a number of age-related diseases in multiple animal studies. (nih.gov)
  • Called Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE), the randomized trial was funded by the National Institute on Aging (NIA) and the National Institute of Diabetes and Digestive and Kidney Diseases, both part of NIH. (nih.gov)
  • It is encouraging to find positive effects when we test interventions that might affect diseases and declines associated with advancing age," notes NIA Director Richard J. Hodes, M.D. "However, we need to learn much more about the health consequences of this type of intervention in healthy people before considering dietary recommendations. (nih.gov)
  • For effective treatment, the risk factors for the diseases merit investigation. (springer.com)
  • The effects of systolic blood pressure (SBP), serum total cholesterol (TC), fasting plasma glucose (FPG), and body mass index (BMI) on the risk of cardiovascular diseases (CVD) have been established in epidemiological studies, but consistent estimates of effect sizes by age and sex are not available. (plos.org)
  • Although the major metabolic risk factors for these diseases have been characterized in epidemiological studies, consistent measurements of their effects by age, sex and region are not available. (plos.org)
  • And catabolic aging is related to chronic diseases. (gcimagazine.com)
  • Once we thought that our genetics were set in stone and that age related diseases (or any disease for that matter) would happen to us because we had the gene for it. (medium.com)
  • As a consequence of aging, the typical chronic diseases of the body and brain such as cardiovascular disease, cancer, hypertension, and Alzheimer's disease (AD) will claim more and more precious human resources. (westonaprice.org)
  • Like many other chronic diseases, AMD is caused by a combination of genetic and environmental risk factors. (sciencemag.org)
  • Older age, showing signs of sepsis on admission, underlying diseases like high blood pressure and diabetes, and the prolonged use of noninvasive ventilation were important factors in the deaths of these patients. (worldhealth.net)
  • The aging population not only in Western and highly developed countries but also in other regions is expected to have a major impact on the rising cases in incontinence and related diseases, according to experts who gathered yesterday during the reporting sessions of the Committees of the ICUD-EAU International Consultation on Incontinence (5th ICI). (uroweb.org)
  • The incidence of infection increases with age, and several studies have shown higher prevalence among women at childbearing age, although children are more exposed to the sources of transmission of this parasite . (scielo.br)
  • It is anticipated that with the overall aging of the population the prevalence of Lower Urinary Tract Symptoms (LUTS) will also increase," said Ian Milsom (SE) during his lecture on epidemiology. (uroweb.org)
  • Understanding the mechanisms and modifiers of healthy brain aging can help inform us not only about how to maintain good cognitive health, but also about what goes awry in conditions like Alzheimer's disease and other age-related neurological disorders and the best options for treating them," Rodrigue said. (utdallas.edu)
  • There has been little study on sleep as a risk factor even though disturbed sleep is a hallmark of the disease, with the disturbed sleep patterns in those with Alzheimer's disease thought to be due to growth of amyloid plaques and resulting neuronal changes. (worldhealth.net)
  • After adjusting data for factors such as BMI, education, age, and sen risks still remained 2.75 times higher, suggesting that Alzheimer's may in part be caused by nighttime sleep disturbances. (worldhealth.net)
  • Results of this study suggest risks for developing Alzheimer's may be reduced with appropriate interventions for disturbed or insufficient sleep, or modifying factors that act more broadly such as work related sleep loss or poor sleep habits. (worldhealth.net)
  • Anything that increases your risk of getting a disease is called a risk factor. (cancercenter.com)
  • We looked at print media coverage two time periods - 2003-04 and 2013-14 - because we hypothesized that as life expectancy increases, age would grow in importance in media representations of cancer but we found the opposite. (thirdage.com)
  • WATCHING WASHINGTON, RAILWAY AGE JANUARY 2020 ISSUE: When Mexico's President Porfirio Diaz lamented more than a century ago of his nation being "so far from God and so close to the United States," he hadn't contemplated the North American Free Trade Agreement (NAFTA), which demonstrably enhances efficiency, encourages innovation, increases consumer purchasing power, makes a wider assortment of goods available and raises standards of living. (railwayage.com)
  • Some studies indicate that high-energy visible light and ultraviolet (UV) light, including sun exposure, may be a contributory factor, but other studies do not. (medicalnewstoday.com)
  • Population-based risk assessment requires data on population exposure to risk factors and on the magnitude of their effects on different disease outcomes , . (plos.org)
  • Extrinsic aging, due to chronic exposure to solar ultraviolet irradiation (photoaging) and smoking, leads to deep and coarse wrinkles, mottled hyperpigmentation and reduced skin elasticity. (gcimagazine.com)
  • Facial skin bears the accumulation of lifelong sun exposure, which is responsible for 80% of the effects of facial skin aging. (gcimagazine.com)
  • Some risk factors for Parkinson's disease include genetics, exposure to environmental toxins, a chemical imbalance in the body and inflammation of tissues in the nervous system. (sharecare.com)
  • 5 DNA damage, exposure to toxins, irradiation, and activation of oncogenes (genetic material that carries the ability to induce cancer) also cause cell aging and death in healthy cells. (westonaprice.org)
  • 2019) Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction‐like phenotype in aged mice. (news-medical.net)
  • However, shorter trials can determine feasibility, safety and effects on quality of life, disease risk factors, predictors of life span and effects on mechanisms influenced by calorie restriction in laboratory animal studies. (nih.gov)
  • CALERIE was a two-year randomized controlled trial in 218 young and middle-aged healthy normal-weight and moderately overweight men and women to measure these outcomes in a calorie restriction group, compared with a control group who maintained their regular diets. (nih.gov)
  • Calorie restriction caused a 47-percent reduction in levels of C-reactive protein, an inflammatory factor linked to cardiovascular disease. (nih.gov)
  • They show that this degree of sustained calorie restriction can influence disease risk factors and possible predictors of longevity in healthy, non-obese people," said Evan Hadley, M.D, director of The National Institute on Aging's Division of Geriatrics and Clinical Gerontology and an author of the paper. (worldhealth.net)
  • It also would be useful to discover if calorie restriction over longer periods has additional effects on predictors of health in old age, and compare its effects with exercise-induced weight loss. (worldhealth.net)
  • That only certain ASD-related behaviors, some of which are not required to satisfy diagnostic criteria, decreased the age of diagnosis suggests the importance of continued physician education. (nih.gov)
  • This finding suggests that paternal age itself plays an independent role in the increased psychiatric risk in offspring, rather than being associated with increased risk through other factors related to late parenthood. (psychcentral.com)
  • Mr Henriksen suggests that factoring is expensive. (accountancyage.com)
  • This fact is intriguing and suggests that key factors that influence the vulnerability of the human organism to the parasite still need to be studied. (scielo.br)
  • Vehicles carrying one or more passengers at the time of the accident increased the likelihood of driver fatality by 114 percent for young men and 70 percent for middle-aged men, but had no significant effect on the injury levels of older male drivers. (medindia.net)
  • Not using safety belts increased the likelihood of injury by 119 percent for young women, 164 percent for middle-aged women and 187 percent for older women. (medindia.net)
  • There are some strength atheletes your age and older who qualify for the elete category, and plenty of sedentary people my age (26) who can't do one good push up. (exrx.net)
  • Levy and her team focused on a cohort of 4,765 older Americans (their average age was 72) who answered five questions about their attitudes toward aging . (baltimoresun.com)
  • The key factors are the older you are, the wealthier you are, the more educated you are, the more likely you are to vote,`` said Lance deHaven-Smith, the Broward provost of Florida Atlantic University, who has studied local and national voting habits. (sun-sentinel.com)
  • It prohibits discrimination against workers because of their older age with respect to any aspect of employment. (eeoc.gov)
  • In addition to prohibiting intentional discrimination against older workers (known as "disparate treatment"), the ADEA prohibits practices that, although facially neutral with regard to age, have the effect of harming older workers more than younger workers (known as "disparate impact"), unless the employer can show that the practice is based on an RFOA. (eeoc.gov)
  • The research team did not investigate the relationships among age, adiposity, and breast density for older women. (appliedradiology.com)
  • As the number of people entering farming drops, the average age of farmers goes up, and the older they are, the less likely they are to invest in water-conserving technologies," says Schuck. (linfield.edu)
  • Older and younger drivers will pay more for their car insurance than those in their middle age because they are more likely to have accidents and make expensive claims for personal injuries. (abi.org.uk)
  • Dr. Karen Rodrigue, a new assistant professor in UT Dallas' School of Behavioral and Brain Sciences (BBS) and the Center for Vital Longevity (CVL), wants to identify the key factors, both environmental and genetic, that impact the brain and cognition as we age. (utdallas.edu)
  • These findings suggest improvements over time in decreasing the age at which children with ASD, especially higher functioning children, receive a diagnosis. (nih.gov)
  • The new findings provide an important advance regarding how the father's age at conception can affect the offspring's risk for schizophrenia. (psychcentral.com)
  • Findings in humans were consistent with mouse studies showing a spike in circulating stem cells and delay in biological aging by promoting regeneration in multiple systems. (eurekalert.org)
  • The findings , published Wednesday in the journal PLOS One, suggest that fighting negative stereotypes about aging could have broad benefits for public health. (baltimoresun.com)
  • Our findings indicate that risk factors for heart disease vary across all ages. (hindawi.com)
  • One in 10 women diagnosed with breast cancer are under the age of 45. (cdc.gov)
  • In addition to the risk factors all women face, some risk factors put young women at a higher risk for getting breast cancer at a young age. (cdc.gov)
  • It's perhaps more likely that HRC will do a bit better than any other Democrat with Baby Boom women entering retirement age. (washingtonmonthly.com)
  • But she's also a woman of an age that matches the rise of professional women, meaning that she has symbolic importance to a whole generation that is now old enough to skew Republican. (washingtonmonthly.com)
  • Accidents occurring in rural areas increased the likelihood of fatalities by 208 percent for young women but had no significant effect on the injury levels of other female age categories. (medindia.net)
  • However, the age at which mothers face a greater chance of experiencing the problem was much younger in other races, with South Asian women at more threat from the age of 20. (figo.org)
  • Fifty one percent of the participants showed active aging (42% men, and 56% women). (youtube.com)
  • Pregnant women living under unfavorable environmental conditions had an approximately two times increased risk of being infected for each risk factor (contact with host animals, presence of vehicles of oocyst transmission). (scielo.br)
  • Breast cancer strikes one in nine women, with increasing risk as we age. (essortment.com)
  • Younger women with family histories of breast disease or who have had cancer in one or both breasts will probably be asked to have a mammogram before age 40. (essortment.com)
  • There are plenty of women who fit this description who will never get the disease, but factors like these can work with other risks to pose a greater threat. (essortment.com)
  • These women are worried because they read online about age-related diminished ovarian reserve or their doctor told them they should consider getting pregnant before the age of 35 or else run the risk of fertility challenges or they have a friend who is having a hard time getting pregnant due to her age. (medium.com)
  • From a Traditional Oriental Medical (the medicine I practice) perspective, we say that if ia women lives in accordance with the Tao she should be fertile until the age of 49. (medium.com)
  • With the appearance of the first crow's feet, many men and women flock to cosmetic surgeons, anti-aging physician specialists, dietary supplements, and cosmetics counters to buy the newest anti-aging products, which are often laden with toxic chemicals. (westonaprice.org)
  • The association between aspirin use and density was more pronounced for women under the age of 60 and for African American women (who represented 41% of the patient cohort). (appliedradiology.com)
  • The professionals at KLEAN Treatment Center are speaking out on a new survey that aims to explain why more middle-aged women are turning to drugs and alcohol. (prweb.com)
  • Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells," Proceedings of the National Academy of Sciences of the United States of America , vol. 95, no. 20, pp. 11709-11714, 1998. (hindawi.com)
  • Placenta growth factor and vascular endothelial growth factor B and C expression in microvascular endothelial cells and pericytes. (hindawi.com)
  • Vascular endothelial growth factor expression in choroidal neovascularization in rats," Graefe's Archive for Clinical and Experimental Ophthalmology , vol. 235, no. 5, pp. 313-319, 1997. (hindawi.com)
  • The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency," Journal of Biological Chemistry , vol. 271, no. 13, pp. 7788-7795, 1996. (hindawi.com)
  • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders," New England Journal of Medicine , vol. 331, no. 22, pp. 1480-1487, 1994. (hindawi.com)
  • Correlation of increased vascular endothelial growth factor with neovascularization and permeability in ischemic central vein occlusion," Archives of Ophthalmology , vol. 120, no. 12, pp. 1644-1650, 2002. (hindawi.com)
  • Intravitreal levels of vascular endothelial growth factor and interleukin-6 are correlated with macular edema in branch retinal vein occlusion," Graefe's Archive for Clinical and Experimental Ophthalmology , vol. 244, no. 3, pp. 309-315, 2006. (hindawi.com)
  • Hierarchical linear statistical modeling will be used to conduct age-period-cohort analyses. (afsp.org)
  • It is expected that cohort and time period play a role in suicide risk above and beyond individual-level factors, and that the degree of social integration and regulation that characterize time periods and cohorts will also be important contributors. (afsp.org)
  • Effect estimates in prior global comparative risk assessment (CRA) analyses of metabolic risk factors including systolic blood pressure (SBP), serum total cholesterol (TC), fasting plasma glucose (FPG), and body mass index (BMI) were based on the Asia Pacific Cohort Studies Collaboration (APCSC) and selected other cohort pooling studies - . (plos.org)
  • 129 Likewise, in a cohort of 811 aging men, subjects reporting higher stress levels scored lower on the Mini-Mental State Examination than their low-stress counterparts. (lifeextension.com)
  • Age beliefs tend to be internalized early in life and then remain stable over the lifespan, without interventions," Levy and her colleagues wrote. (baltimoresun.com)
  • To compare and contrast characteristics and determinants of fatal all-terrain vehicle (ATV) crashes among pediatric age groups. (aappublications.org)
  • The benefit of intensive lipid lowering in all age groups supports the need for intensive modification of risk in all patients regardless of age. (ahajournals.org)
  • While overall toxicity was similar between the two age groups, specific moderate and severe toxicities occurred more frequently in the elderly. (rxpgnews.com)
  • For all risk factors, proportional effects declined with age, were generally consistent by sex, and differed by region in only a few age groups for certain risk factor-disease pairs. (plos.org)
  • 2.00 mmol/L. Epoch (age at sampling) analysis in this group showed no difference in blood glucose levels across the different feeding groups but revealed a statistically significant greater kb concentration for infants who were exclusively breastfed. (aappublications.org)
  • The data shows the average premiums that customers of different age groups pay for their car insurance, compared to the cost of the average claim they make. (abi.org.uk)
  • The questions for these age groups are picture based with simple supporting text and Milly the Mouse to guide you through. (lovereading4kids.co.uk)
  • During the first season, the finalists were split into three categories: 16-24s (soloists aged 16 to 24), Over 25s (soloists aged 25 and over) and Groups (including duos). (wikipedia.org)
  • less is known about the molecular mechanisms that determine cell survival, except for the many classical biological experiments that have established that in vertebrate development, neuronal cell death is, in large measure but not uniquely, under the control of neuronotrophic factors such as the nerve growth factor protein, NGF (Thoenen et al. (springer.com)
  • Until recently, there has been controversy over the role of GDF11 in aging, and its mechanisms were largely unknown. (news-medical.net)
  • In graduate school, she studied how brain health and disease influence behavior, with a particular emphasis on the effects of the aging process on brain structure. (utdallas.edu)
  • Our finding could provide a rationale for a public-health campaign to combat the societal sources of negative age beliefs. (baltimoresun.com)
  • She is currently an Associate Professor in the Department of Sociology and the Institute for Health, Health Care Policy and Aging Research at Rutgers University. (afsp.org)
  • The changing nature of work and health in midlife has reduced social integration and regulation, which have been shown to be risk factors for suicidal ideation and behavior. (afsp.org)
  • Coping with aging was composed of independence in basic and instrumental activities of daily living, free from symptoms of depression, good mental state, and perception of health as good. (youtube.com)
  • Multifactorial inheritance refers to the pattern of inheritance of certain health problems caused by a combination of both genetic and environmental factors. (ucsf.edu)
  • Disease prevention begins at a young age, while bodies are still in good health and we have time to change lifestyles to develop life-sustaining habits. (essortment.com)
  • When it comes to fertility and getting pregnant, overall health should be more of the concern than a woman's actual age. (medium.com)
  • You can actually make lifestyle changes that can positively impact your health (and, dare I say - slow down the aging process). (medium.com)
  • How this relates to the whole age-fertility conversation is that you can shift your lifestyle to support the health of the cells in your body and thereby improve the quality of the eggs in your ovaries. (medium.com)
  • I know firsthand how epigenetics works, as I got pregnant naturally and easily at the age of 40 by living the lifestyle that I preach - one that supports the health of my cells and my physiological age. (medium.com)
  • Establishing factors related to asthma remission could have clinical and public health implications. (bmj.com)
  • To pursue good health as we age becomes more and more important in order to enjoy a disease-free and rewarding quality of life during our later decades. (westonaprice.org)
  • Interestingly, depression seems to worsen cognitive dysfunction, but poorer cognitive health predisposes aging individuals to depression as well. (lifeextension.com)
  • This health supplement from NutriCology® contains NT Factor® (a patent-pending formula). (pureformulas.com)
  • Lifestyle factors such as physical exercise (+), mental stimulation (+), good sleep hygiene (+), substance abuse (-), sedentary lifestyle (-), chronic stress and depression (-), social isolation (-), and poor health (-) can either promote or discourage positive and negative neuroplasticity, which in turn impacts cognitive reserve. (dovepress.com)
  • and was designed to mirror long term health of thousands of volunteers to investigate and discover risk factors for age related conditions. (worldhealth.net)
  • There are multiple factors of skin aging, including intrinsic, extrinsic, hormonal and catabolic, which will be discussed in further detail here. (gcimagazine.com)
  • Intrinsic skin aging is a slow process with clinical features such as smooth, pale, dry and less elastic skin having fine wrinkles that are not apparent until old age. (gcimagazine.com)
  • Juvenile protective factors (JPFs), intrinsic to an immature organism, help to maintain or enhance certain physiological functions across all or some stages of postnatal development (i.e., segment of the life span between birth and sexual maturity), but diminish or disappear as the organism transitions from one maturational stage to the next. (nih.gov)
  • One of the hallmarks of aging tissues is the accumulation of a variety of lipid-derived pigments called lipofuscins, so-called "wear-and-tear" pigments. (truthinaging.com)
  • Within this group, 167 had experienced a severe respiratory infection or disease before age 5, while 85 healthy controls lacked such a history. (medpagetoday.com)
  • After adjusting for other factors that may influence risk, including smoking, age, sex and vitamin C intake, those in the group with the highest intake of polyunsaturated fat had a 50 percent reduced chance of developing early AMD compared with those who ate the least. (emaxhealth.com)
  • In the same age group, RRs for 1 mmol/L higher TC were 1.44 (1.29-1.61) for IHD and 1.20 (1.15-1.25) for ischemic stroke. (plos.org)
  • For 1 mmol/L higher FPG, RRs in this age group were 1.18 (1.08-1.29) for IHD and 1.14 (1.01-1.29) for total stroke. (plos.org)
  • I further broke this down by looking at the characteristics of the youngest 15% in each group, which occurs at age 29 for the 750-799 group and 43 for the 800-850. (fico.com)
  • A group of aging subjects diagnosed with depression completed various cognitive tests and their results were compared to those of age and sex - matched, non-depressed control subjects. (lifeextension.com)
  • We are soliciting public input about how we should consider the vocational factors of age, education, and work experience in adult disability claims under titles II and XVI of the Social Security Act (Act). (federalregister.gov)
  • The purpose of this FOA is to invite pilot/feasibility projects for: 1) descriptive studies to identify putative juvenile protective factors, 2) experimental studies to test hypotheses about their effects on aging and 3) translational studies to characterize potential beneficial and adverse effects of maintaining or modulating the level of juvenile protective factors in adult life. (nih.gov)
  • This FOA is uniquely focused on animal and clinical studies which involve comparisons between juvenile versus adult states or between stages of postnatal development to identify putative JPFs and their effects on aging. (nih.gov)
  • Paternal factors including changed paternity, short stature and father born SGA also contribute. (nih.gov)
  • In the meantime, we do know that exercise and maintaining a healthy weight and diet can contribute to healthy aging. (nih.gov)
  • Conclusions: Acceptance of technology in the pre-implementation stage is influenced by multiple factors. (nivel.nl)
  • What we eat supplies the building blocks for our body's cells, energy-producing mitochondria, enzymes, and co-factors that build or break the body. (westonaprice.org)
  • and an anti-thrombotic role, which is observed at a young age. (coursera.org)
  • While jurors weren't supposed to consider his age - that he was too young to drive, vote or drink - it was a fact difficult to ignore. (sun-sentinel.com)
  • The understanding of the molecular connections between specific food components and genes that regulate aging and regeneration allows food to be used to promote cellular changes that are safe but more coordinated than those caused by drugs. (eurekalert.org)
  • Aging has been predetermined in our genes, experts say, and cells can only divide forty to sixty times before they reach the "Hayflick Limit," a theory advanced in 1961 by Leonard Hayflick at the Wistar Institute in Philadelphia, Pennsylvania. (westonaprice.org)