African Swine Fever Virus: The lone species of the genus Asfivirus. It infects domestic and wild pigs, warthogs, and bushpigs. Disease is endemic in domestic swine in many African countries and Sardinia. Soft ticks of the genus Ornithodoros are also infected and act as vectors.African Swine Fever: A sometimes fatal ASFIVIRUS infection of pigs, characterized by fever, cough, diarrhea, hemorrhagic lymph nodes, and edema of the gallbladder. It is transmitted between domestic swine by direct contact, ingestion of infected meat, or fomites, or mechanically by biting flies or soft ticks (genus Ornithodoros).Classical swine fever virus: A species of the PESTIVIRUS genus causing exceedingly contagious and fatal hemorrhagic disease of swine.Iridoviridae: A family of large icosahedral DNA viruses infecting insects and poikilothermic vertebrates. Genera include IRIDOVIRUS; RANAVIRUS; Chloriridovirus; Megalocytivirus; and Lymphocystivirus.Classical Swine Fever: An acute, highly contagious disease affecting swine of all ages and caused by the CLASSICAL SWINE FEVER VIRUS. It has a sudden onset with high morbidity and mortality.Swine: Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).Vero Cells: A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.Asfarviridae: A family of double-stranded DNA viruses containing one genus Asfivirus. It is the source of AFRICAN SWINE FEVER.Ornithodoros: A genus of softbacked TICKS, in the family ARGASIDAE, serving as the vector of BORRELIA, causing RELAPSING FEVER, and of the AFRICAN SWINE FEVER VIRUS.Cercopithecus aethiops: A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.Viral Structural Proteins: Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).Yellow fever virus: The type species of the FLAVIVIRUS genus. Principal vector transmission to humans is by AEDES spp. mosquitoes.Viral Proteins: Proteins found in any species of virus.Hemadsorption: A phenomenon manifested by an agent or substance adhering to or being adsorbed on the surface of a red blood cell, as tuberculin can be adsorbed on red blood cells under certain conditions. (Stedman, 25th ed)Polyproteins: Proteins which are synthesized as a single polymer and then cleaved into several distinct proteins.Rift Valley fever virus: A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.Genes, Viral: The functional hereditary units of VIRUSES.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.DNA Viruses: Viruses whose nucleic acid is DNA.Virus Replication: The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.Open Reading Frames: A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).Virus Assembly: The assembly of VIRAL STRUCTURAL PROTEINS and nucleic acid (VIRAL DNA or VIRAL RNA) to form a VIRUS PARTICLE.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Sus scrofa: A species of SWINE, in the family Suidae, comprising a number of subspecies including the domestic pig Sus scrofa domestica.DNA, Viral: Deoxyribonucleic acid that makes up the genetic material of viruses.Virulence: The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.Swine Diseases: Diseases of domestic swine and of the wild boar of the genus Sus.ArtiodactylaBase Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Ticks: Blood-sucking acarid parasites of the order Ixodida comprising two families: the softbacked ticks (ARGASIDAE) and hardbacked ticks (IXODIDAE). Ticks are larger than their relatives, the MITES. They penetrate the skin of their host by means of highly specialized, hooked mouth parts and feed on its blood. Ticks attack all groups of terrestrial vertebrates. In humans they are responsible for many TICK-BORNE DISEASES, including the transmission of ROCKY MOUNTAIN SPOTTED FEVER; TULAREMIA; BABESIOSIS; AFRICAN SWINE FEVER; and RELAPSING FEVER. (From Barnes, Invertebrate Zoology, 5th ed, pp543-44)Virion: The infective system of a virus, composed of the viral genome, a protein core, and a protein coat called a capsid, which may be naked or enclosed in a lipoprotein envelope called the peplos.Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.Hemorrhagic Fever Virus, Crimean-Congo: A species of NAIROVIRUS of the family BUNYAVIRIDAE. It is primarily transmitted by ticks and causes a severe, often fatal disease in humans.Cytopathogenic Effect, Viral: Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysosomal enzymes, changes in cell membrane permeability, diffuse changes in intracellular structures, presence of viral inclusion bodies, and chromosomal aberrations. It excludes malignant transformation, which is CELL TRANSFORMATION, VIRAL. Viral cytopathogenic effects provide a valuable method for identifying and classifying the infecting viruses.Antibodies, Viral: Immunoglobulins produced in response to VIRAL ANTIGENS.Yellow Fever: An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus. The severe form is characterized by fever, HEMOLYTIC JAUNDICE, and renal damage.Macrophages: The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)Cell Line: Established cell cultures that have the potential to propagate indefinitely.Rift Valley Fever: An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.Malawi: A republic in southern Africa east of ZAMBIA and MOZAMBIQUE. Its capital is Lilongwe. It was formerly called Nyasaland.Genome, Viral: The complete genetic complement contained in a DNA or RNA molecule in a virus.Vaccinia virus: The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.Pestivirus: A genus of FLAVIVIRIDAE, also known as mucosal disease virus group, which is not arthropod-borne. Transmission is by direct and indirect contact, and by transplacental and congenital transmission. Species include BORDER DISEASE VIRUS, bovine viral diarrhea virus (DIARRHEA VIRUS, BOVINE VIRAL), and CLASSICAL SWINE FEVER VIRUS.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Capsid: The outer protein protective shell of a virus, which protects the viral nucleic acid.

A lipid modified ubiquitin is packaged into particles of several enveloped viruses. (1/269)

An anti-ubiquitin cross-reactive protein which migrates more slowly (6.5 kDa) by SDS-PAGE than ubiquitin was identified in African swine fever virus particles. This protein was extracted into the detergent phase in Triton X-114 phase separations, showing that it is hydrophobic, and was radiolabelled with both [3H]palmitic acid and [32P]orthophosphate. This indicates that the protein has a similar structure to the membrane associated phosphatidyl ubiquitin described in baculovirus particles. A similar molecule was found in vaccinia virus and herpes simplex virus particles, suggesting that it may be a component of uninfected cell membranes, which is incorporated into membrane layers in virions during morphogenesis.  (+info)

Nuclear and nucleolar localization of an African swine fever virus protein, I14L, that is similar to the herpes simplex virus-encoded virulence factor ICP34.5. (2/269)

PCR analysis of the genomes of 18 different African swine fever virus (ASFV) isolates showed that the I14L open reading frame (ORF) was present as either a long form or short form in all of the isolates. Sequencing of the ORF from eight isolates confirmed that both forms of the ORF were well conserved. Antisera raised against the I14L protein identified the long form of the protein as a 21 kDa protein expressed late during ASFV infection. Immunofluorescent analysis of transiently expressed haemagglutinin-tagged forms of the I14L protein showed that the long form of the protein localized predominantly to the nucleus and within the nucleoli. In contrast, although the short form of the protein was also present predominantly in the nucleus, it did not localize to the nucleoli. Deletion of the N-terminal 14 amino acids from the long form of the I14L protein, which includes a high proportion of basic Arg/Lys residues, abolished the specific nucleolar localization of the protein, although the protein was still present in the nucleus. Addition of this 14 amino acid sequence to beta-galactosidase or replacement of the N-terminal 14 amino acids of the I14L short form with those from the long form directed both of these modified proteins to the nucleolus. This indicates that this 14 amino acid sequence contains all the signals required for nucleolar localization.  (+info)

Modulation of monocytic cell activity and virus susceptibility during differentiation into macrophages. (3/269)

A major component of innate immune responses relies on monocytes and macrophages, virus infection of which will pose a particular problem for immunological defense. Consequently, the monocytic cell differentiation pathway was analyzed in terms of cellular modulations therein and their relation to monocytotropic virus infection. Differentiation was characterized by down-regulation of CD14, MHC Ags, the monocytic SWC1 marker, and p53; concomitant up-regulation of the SWC9 macrophage marker, a putative porcine CD80 (detected with anti-human CD80 Ab), and acid phosphatase secretion were also characteristic. Elevated phagocytic and endocytic activities as well as endosomal/lysosomal acidification were identified as being important to the macrophage. In contrast, monocytes possessed high accessory activity. This was multifactorial, concomitantly requiring 1) high MHC Ag expression; 2) enzyme activity of esterase, peroxidase, myeloperoxidase, and 5' nucleotidase in preference to glucosidase, galactosidase, and glucuronidase; and 3) elevated capacity for spontaneous IL-1 production. Only with all parameters was efficient stimulation of Ag-specific lymphocytes possible. These results point to a continuous process during differentiation, involving inter-related characteristics linking the more accessory monocyte to the scavenger macrophage, both in vitro and in vivo. Of particular interest was how these characteristics related to monocytotropic virus infection, and how a particular virus could show a clear preference for the differentiating macrophages. Such results not only further our understanding of porcine immunology, but also provide evidence and a potential model for the determination and characterization of monocytotropic virus-host cell interactions.  (+info)

The biological effects induced in mice by p36, a proteinaceous factor of virulence produced by African swine fever virus, are mediated by interleukin-4 and also to a lesser extent by interleukin-10. (4/269)

We have previously presented indirect evidence that both specific immunosuppression and lymphocyte mitogenicity induced in mice by p36, a proteinaceous factor of virulence produced by porcine monocytes infected by African swine fever virus, were consistent with a Th2-driven response. Here we show: (1) Interleukin-4 (IL-4) and interleukin-10 (IL-10) mRNA expression in the spleen and thymus of C57BL/6 mice were displayed early after p36 inoculation. The expression of thymic IL-10 mRNA occurred, however, later than that of IL-4 mRNA. (2) Increased serum levels of these two cytokines were also soon detected after the protein inoculation. (3) Both immunosuppressive and mitogenic effects of p36 were absent in IL-4 gene-targeted mice and partially abrogated in mice depleted of IL-4 by neutralizing monoclonal antibodies. (4) IL-10 depletion abrogated the immunosuppressive but not the p36 lymphocyte mitogenic biological effects. (5) The increase in the serum concentrations of both IL-4 and IL-10 were lower in thymectomized than in non-thymectomized mice. (6) The expression of interferon-gamma (IFN-gamma) mRNA was weakly or not at all induced in p36-treated mice. Taken together, these results are in agreement with the promotion of a Th2 immune response induced by p36.  (+info)

Replication of African swine fever virus DNA in infected cells. (5/269)

We have examined the ultrastructural localization of African swine fever virus DNA in thin-sections of infected cells by in situ hybridization and autoradiography. Virus-specific DNA sequences were found in the nucleus of infected Vero cells at early times in the synthesis of the viral DNA, forming dense foci localized in proximity to the nuclear membrane. At later times, the viral DNA was found exclusively in the cytoplasm. Electron microscopic autoradiography of African swine fever virus-infected macrophages showed that the nucleus is also a site of viral DNA replication at early times. These results provide further evidence of the existence of nuclear and cytoplasmic stages in the synthesis of African swine fever virus DNA. On the other hand, alkaline sucrose sedimentation analysis of the replicative intermediates synthesized in the nucleus and cytoplasm of infected macrophages showed that small DNA fragments ( approximately 6-12S) were synthesized in the nucleus at an early time, whereas at later times, larger fragments of approximately 37-49S were labeled in the cytoplasm. Pulse-chase experiments demonstrated that these fragments are precursors of the mature cross-linked viral DNA. The formation of dimeric concatemers, which are predominantly head-to-head linked, was observed by pulsed-field electrophoresis and restriction enzyme analysis at intermediate and late times in the replication of African swine fever virus DNA. Our findings suggest that the replication of African swine fever virus DNA proceeds by a de novo start mechanism with the synthesis of small DNA fragments, which are then converted into larger size molecules. Ligation or further elongation of these molecules would originate a two-unit concatemer with dimeric ends that could be resolved to generate the genomic DNA by site-specific nicking, rearrangement, and ligation as has been proposed in the de novo start model of Baroudy et al. (B. M. Baroudy, S. Venkatesam, and B. Moss, 1982, Cold Spring Harbor Symp. Quant. Biol. 47, 723-729) for the replication of vaccinia virus DNA.  (+info)

The African swine fever virus prenyltransferase is an integral membrane trans-geranylgeranyl-diphosphate synthase. (6/269)

In a previous study, it was shown that the protein encoded by the gene B318L of African swine fever virus (ASFV) is a trans-prenyltransferase that catalyzes in vitro the condensation of farnesyl diphosphate and isopentenyl diphosphate to synthesize geranylgeranyl diphosphate and longer chain prenyl diphosphates (Alejo, A., Yanez, R. J., Rodriguez, J. M., Vinuela, E., and Salas, M. L. (1997) J. Biol. Chem. 272, 9417-9423). To investigate the in vivo function of the viral enzyme, we have determined, in this work, its subcellular localization and activity in cell extracts. Two systems were used in these studies: cells infected with ASFV and cells infected with a recombinant pseudo-Sindbis virus carrying the complete B318L gene. In this latter system, the trans-prenyltransferase was found to colocalize with the endoplasmic reticulum marker protein-disulfide isomerase, whereas in cells infected with ASFV, the viral enzyme was present in cytoplasmic viral assembly sites, associated with precursor viral membranes derived from the endoplasmic reticulum. In addition, after subcellular fractionation, the viral enzyme partitioned into the membrane fraction. Extraction of membrane proteins with alkaline carbonate and Triton X-114 indicated that the ASFV enzyme behaved as an integral membrane protein. The membrane enzyme synthesized predominantly all-trans-geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate. These results indicate that the viral B318L protein is a trans-geranylgeranyl-diphosphate synthase, being the only enzyme of this type that is known to have a membrane localization.  (+info)

African swine fever virus: a B cell-mitogenic virus in vivo and in vitro. (7/269)

The two major characteristics of pathogenesis in African swine fever virus (ASFV) infections of domestic pigs are massive B-cell apoptosis and haemorrhage. The effects of ASFV on porcine B cells have therefore been systematically examined in vivo, by using virus-infected pigs and SCID-Beige mice reconstituted with porcine bone marrow, and in vitro, by using porcine B-cell lines and B cells from normal and ASFV-infected pigs. Secretion of porcine Ig was stimulated by ASFV both in vivo and in bone marrow cultures in vitro, with the virulent Malawi isolate of ASFV being the most effective. Stimulation of Ig secretion in vitro depended on the presence of ASFV-infected macrophages and did not occur with supernatants from ASFV-infected macrophages. Although the virus alone did not stimulate proliferation of purified B cells in vitro, it was co-stimulatory with CD154 (CD40 ligand). The B cells recovered from ASFV-infected porcine lymphoid tissue were of activated surface marker phenotypes and, interestingly, expressed diminished levels of the B-cell co-stimulatory surface molecule CD21. In addition, they were highly sensitive to IL-4 and CD154. These results may be integrated into a model of pathogenesis in which those B cells activated indirectly as a result of virulent ASFV infection of macrophages are not rescued from apoptosis through interaction with CD154, due to the drastic depletion of T cells that occurs early in infection. The consequently diminished specific anti-ASFV antibody response would favour survival of the virus, with the non-specific hypergammaglobulinaemia being perhaps another example of pathogen-mediated immune deviation.  (+info)

African swine fever virus replication in the midgut epithelium is required for infection of Ornithodoros ticks. (8/269)

Although the Malawi Lil20/1 (MAL) strain of African swine fever virus (ASFV) was isolated from Ornithodoros sp. ticks, our attempts to experimentally infect ticks by feeding them this strain failed. Ten different collections of Ornithodorus porcinus porcinus ticks and one collection of O. porcinus domesticus ticks were orally exposed to a high titer of MAL. At 3 weeks postinoculation (p.i.), <25% of the ticks contained detectable virus, with viral titers of <4 log(10) 50% hemadsorbing doses/ml. Viral titers declined to undetectability in >90% of the ticks by 5 weeks p.i. To further study the growth defect, O. porcinus porcinus ticks were orally exposed to MAL and assayed at regular intervals p.i. Whole-tick viral titers dramatically declined (>1,000-fold) between 2 and 6 days p.i., and by 18 days p.i., viral titers were below the detection limit. In contrast, viral titers of ticks orally exposed to a tick-competent ASFV isolate, Pretoriuskop/96/4/1 (Pr4), increased 10-fold by 10 days p.i. and 50-fold by 14 days p.i. Early viral gene expression, but not extensive late gene expression or viral DNA synthesis, was detected in the midguts of ticks orally exposed to MAL. Ultrastructural analysis demonstrated that progeny virus was rarely present in ticks orally exposed to MAL and, when present, was associated with extensive cytopathology of phagocytic midgut epithelial cells. To determine if viral replication was restricted only in the midgut epithelium, parenteral inoculations into the hemocoel were performed. With inoculation by this route, a persistent infection was established although a delay in generalization of MAL was detected and viral titers in most tissues were typically 10- to 1,000-fold lower than those of ticks injected with Pr4. MAL was detected in both the salivary secretion and coxal fluid following feeding but less frequently and at a lower titer compared to Pr4. Transovarial transmission of MAL was not detected after two gonotrophic cycles. Ultrastructural analysis demonstrated that, when injected, MAL replicated in a number of cell types but failed to replicate in midgut epithelial cells. In contrast, ticks injected with Pr4 had replicating virus in midgut epithelial cells. Together, these results indicate that MAL replication is restricted in midgut epithelial cells. This finding demonstrates the importance of viral replication in the midgut for successful ASFV infection of the arthropod host.  (+info)

*African swine fever virus

... (ASFV) is the causative agent of African swine fever (ASF). The virus causes a haemorrhagic fever ... In July, 3 farms discovered African swine fever in Estonia. [...] African swine fever spreads to farmed pigs, 500 animals to be ... Viruses portal Animal viruses Denyer, M. S.; Wilkinson, P. J. (1998). "African Swine Fever". Encyclopedia of Immunology. p. 54 ... 2008). "African Swine Fever Virus". Animal Viruses: Molecular Biology. Caister Academic Press. ISBN 978-1-904455-22-6. Dixon, L ...

*Thymidine kinase in clinical chemistry

"Sequence and evolutionary relationships of African swine fever virus thymidine kinase". Virology. 178 (1): 301-4. doi:10.1016/ ... virus specific thymidine kinases have been identified in Herpes simplex virus, Varicella zoster virus and Epstein-Barr virus. ... Kit S, Kit M, Qavi H, Trkula D, Otsuka H (1983). "Nucleotide sequence of the herpes simplex virus type 2 (HSV-2) thymidine ... McDougall JK, Masse TH, Galloway DA (1980). "Location and cloning of the herpes simplex virus type 2 thymidine kinase gene". J ...

*Desert warthog

... s were experimentally infected with the virus that causes African swine fever. It was found that the warthogs ... with African swine fever virus". Onderstepoort Journal of Veterinary Research. 47 (1): 19-22. ISSN 0030-2465. Child, Graham; ... During the late nineteenth century, P. aethiopicus became extinct in South Africa. Subsequently, study of mDNA as well as ... The desert warthog is native to the Horn of Africa. Its current range extends from southeastern Ethiopia through western ...

*Thymidine kinase

The thymidine kinases from pox viruses, African swine fever virus, Herpes simplex virus, Varicella zoster virus and Epstein- ... African swine fever virus (ASFV) and Fish lymphocystis disease virus (FLDV). The major capsid protein of insect iridescent ... "Sequence and evolutionary relationships of African swine fever virus thymidine kinase". Virology. 178 (1): 301-4. doi:10.1016/ ... Genes for virus specific thymidine kinases have been identified in Herpes simplex virus, Varicella zoster virus and Epstein- ...

*Carios erraticus

The tick transmits the African swine fever virus only in Spain and Portugal. The tick feeds at night, ingesting blood to ... This species carries the pathogenic Qalyub and African swine fever viruses and the spirochetes Borrelia crocidurae and Borrelia ... "Distribution and biology of Ornithodoros erraticus in parts of Spain affected by African swine fever". The Veterinary Record. ... Kurstak, Edouard; R.G. Marusyk, F.A. Murphy, and M.H.V. Van Regenmortel (1990). Applied Virology Research, Volume 2: Virus ...

*GALNT2

"African Swine Fever Virus Causes Microtubule-Dependent Dispersal of trans-Golgi Network" (PDF). Bennett EP, Hassan H, Clausen H ...

*Viroplasm

Salas, María L.; Andrés, Germán (2013). "African swine fever virus morphogenesis". Virus Research. 173: 29-41. doi:10.1016/j. ... Viroplasms have been found in the cauliflower mosaic virus, rotavirus, vaccinia virus and the rice dwarf virus. These appear ... The number and the size of viroplasms depend on the virus, the virus isolate, hosts species, and the stage of the infection. ... The viroplasm could also prevent virus degradation by proteases and nucleases. In the case of the Cauliflower mosaic virus ( ...

*Giant virus

... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus". ... Largest giant viruses with complete sequenced genomes The whole list is in the Giant Virus Toplist created by the Giant Virus ... having the largest capsid diameters of all known viruses. Viral replication in giant viruses occurs within large circular virus ... A giant virus is a very large virus, some of which are larger than typical bacteria. They are giant nucleocytoplasmic large DNA ...

*Immunoglobulin C2-set domain

Kutish GF, Rock DL, Afonso CL, Borca MV, Irusta P, Carrillo C, Brun A, Sussman M (1994). "An African swine fever virus gene ... CD2 displays structural and functional similarities with African swine fever virus (ASFV) LMW8-DR, a protein that is involved ...

*Radioimmunoprecipitation assay buffer

... of a radioimmunoprecipitation assay to immunoblotting and ELISA for detection of antibody to African swine fever virus". J. Vet ...

*Cassia sieberiana

... and African swine fever virus. In the same study, it was shown that the roots contain flavonoids, anthracenic derivatives, and ... It is used for multiple medical purposes in Africa and is found in the secondary jungle of a forest. Individuals of this ... Cassia sieberiana, drumstick tree, is a tree in the Fabaceae family native to Africa. It ranges from 10-20 metres in height and ... It is also found in East Africa. Cassia sieberiana grows best in well drained, humid soils with an annual rainfall of ...

*Dunaliella

In vitro inhibition of the replication of haemorrhagic septicaemia virus (VHSV) and African swine fever virus (ASFV) by ...

*Asfarviridae

The viruses in the Asfivirus genus infects swine, resulting in an onset of African swine fever. The name of this family and ... African swine fever and related viruses. Only a single species has been described to date for this genus. This group of viruses ... Group: dsDNA Order: Unassigned Family: Asfarviridae Genus: Asfivirus African swine fever virus The virons consist of an ... Index of Viruses-Asfarviridae (2006). In: ICTVdB-The Universal Virus Database, version 4. Büchen-Osmond, C (Ed), Columbia ...

*Haiti-United States relations

... during the 1980s as part of an effort to combat an outbreak of the African swine fever virus. Haiti has been plagued for ... Hjelmgaard, Kim (12 January 2018). "U.N., African countries blast Trump's 'racist' words in angry global backlash". USA TODAY. ... Fram, Alan; Lemire, Jonathan (12 January 2018). "Trump denies he referred to Africa as a 'shithole'". Chicago Tribune. ... and African countries, Donald Trump said "Why are we having all these people from shithole countries come here". After the ...

*Taxonomic list of viruses

African swine fever virus Family: Baculoviridae Genus: Alphabaculovirus Adoxophyes honmai nucleopolyhedrovirus Agrotis ipsilon ... virus Uganda S virus Usutu virus Wesselsbron virus West Nile virus Yaounde virus Yellow fever virus Yokose virus Zika virus ... Bujaru virus Candiru virus Chilibre virus Frijoles virus Punta Toro virus Rift Valley fever virus Salehabad virus Sandfly fever ... virus Shuni virus Simbu virus Tacaiuma virus Tete virus Thimiri virus Timboteua virus Turlock virus Wyeomyia virus Zegla virus ...

*Dinodnavirus

... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus. ... The type species is Heterocapsa circularisquama DNA virus 01. The virus has an isosahedral capsid ~200 nanometers in diameter. ... Dinodnavirus is a genus of viruses that infect dinoflagellates. This genus belongs to the clade of nucleocytoplasmic large DNA ... During replication virions emerge from a specific cytoplasm compartment - the 'viroplasm' - which is created by the virus. The ...

*ASF

... a car wax chemical African swine fever virus (ASFV), the causative agent of African swine fever (ASF) Alaska Satellite Facility ... an aviation security division in Pakistan African Standby Force, an international peace force controlled by the African Union ...

*List of MeSH codes (B04)

... torque teno virus MeSH B04.280.049.035 --- african swine fever virus MeSH B04.280.065.249 --- granulovirus MeSH B04.280.065.500 ... torque teno virus MeSH B04.909.204.102 --- asfarviridae MeSH B04.909.204.102.035 --- african swine fever virus MeSH B04.909. ... classical swine fever virus MeSH B04.909.777.411 --- hepatitis delta virus MeSH B04.909.777.415 --- hepatitis e virus MeSH ... yellow fever virus MeSH B04.820.250.400 --- gb virus a MeSH B04.820.250.405 --- gb virus b MeSH B04.820.250.410 --- GB virus C ...

*Russian National Reinsurance Company

They include a wide range of risks in agricultural insurance (e.g. coverage of losses related to African swine fever virus), ...

*DNA virus

... and the large eukaryal DNA viruses: the African swine fever virus (Asfarviridae), Chlorella viruses (Phycodnaviridae) and ... fish lymphocystis disease virus (Iridoviridae) and chlorella virus (Phycoviridae). The pol genes of the African swine fever ... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus". ... human adenovirus infection Family Ampullaviridae Family Ascoviridae Family Asfarviridae-includes African swine fever virus ...

*Arbovirus

With the exception of the African swine fever virus, which belongs to the Asfarviridae family of viruses, all major clinically ... West Nile virus (WNV) Spondweni group Spondweni virus Zika virus (ZIKV) Yellow fever virus group Yellow fever virus (YFV) ... La Crosse encephalitis virus (LACV) Genus Phlebovirus Rift Valley fever virus (RVFV) Toscana virus (TOSV) Heartland virus ... Tick-borne encephalitis virus (TBEV) Mosquito-borne viruses Dengue virus group Dengue virus (DENV) Japanese encephalitis virus ...

*John Burns Brooksby

His research also extended into African swine fever and blue tongue viruses. He prepared the UK for an epidemic of swine ... His studies included the survival of the virus in meat, concluding that the virus made use of the animal meat non-viable, a ... His advice was taken on an international level, and he played a strong role in disease control both in Africa and the Middle ... The Anti-bodies in Foot-and-Mouth Disease (1949) Studies of the Complement-Fixation Reaction in Virus Systems (1953) Plus many ...

*Infectious salmon anemia virus

... for example Arboviruses such as dengue fever, West Nile virus, or African swine fever virus. Clinical signs and pathology may ... It is not known whether the ISA virus can reproduce itself in the sea louse, although this is a possibility as viruses can use ... ISA is caused by the infectious salmon anemia virus (ISAV). ISAV, a RNA virus, is the only species in the genus "Isavirus" ... There are several distinct strains of the virus. The most common are a European strain and a North American strain. ISA virus ...

*Nucleocytoplasmic large DNA viruses

This virus is the cause of African swine fever. Some of the symptoms for this flu include fever, high pulse, fast breathing, ... "African swine fever (ASF) , animal disease". Encyclopedia Britannica. Retrieved 2017-12-07. "Iridoviridae-Iridoviridae-dsDNA ... The nucleocytoplasmic large DNA viruses, are a new order of viruses that contain the Megavirales or giant viruses. There are ... the difference is that the African swine flu can not be cured. There is no vaccine developed to fight this virus. The ...

*Ornithodoros savignyi

... it plays a role in transmitting the virus causing African swine fever which in 2013 was found 35 km north of Pretoria. A ... Charrel, RN; Fagbo, S; Moureau, G; Alqahtani, MH; Temmam, S; de Lamballerie, X (2007). "Alkhurma hemorrhagic fever virus in ... and is a carrier of a flavivirus causing Alkhurma hemorrhagic fever (AHFV). The closely related Kyasanur Forest disease virus ( ... Occurring in semi-desert areas of Africa, Saudi Arabia and other parts of the Persian Gulf, India, Sri Lanka and into Asia, it ...

*Aflatoxin B1

Exposure is therefore most common in Southeast Asia, South America, and Sub-Saharan Africa. Aflatoxin B1 can permeate through ... Occupational exposure to aflatoxin B1 has also been reported in swine and poultry production. While aflatoxin B1 contamination ... Symptoms include anorexia, malaise, and low-grade fever. Subacute toxicity Subacute toxicity studies of aflatoxin B1 in animals ... Prevalence of hepatocellular carcinoma in individuals exposed to aflatoxin, increases with co-infection of hepatitus B virus. ...
African swine fever virus used to occur primarily in Africa. There had been occasional incursions into Europe or America which apart from the endemic situation on the island of Sardinia always had been successfully controlled. But following an introduction of the virus in 2007, it now has expanded its geographical distribution into Caucasus and Eastern Europe where it has not been controlled, to date. African swine fever affects domestic and wild pig species, and can involve tick vectors. The ability of the virus to survive within a particular ecosystem is defined by the ecology of its wild host populations and the characteristics of livestock production systems, which influence host and vector species densities and interrelationships. African swine fever has high morbidity in naïve pig populations and can result in very high mortality. There is no vaccine or treatment available. Apart from stamping out and movement control, there are no control measures, thereby potentially resulting in ...
African swine fever virus, illustration. This virus is a member of the iridovirus group that causes African swine fever. Unlike other DNA- containing vertebrate viruses (except the poxviruses), the iridovirus replicates in the host cells cytoplasm (most others replicate in the nucleus). - Stock Image F016/8841
African swine fever is a devastating hemorrhagic fever of pigs, caused by the African swine fever virus (ASFV). In Africa, the presence of a sylvatic cycle involving warthogs and soft ticks means that the risk of introduction of ASFV into domestic swine is always present. Bushpigs (Potamochoerus larvatus) are nocturnal, susceptible to ASFV and share a natural interface with both warthogs and domestic pigs. The role of the bushpig in the epidemiology of ASFV if any is not understood, yet control strategies of the disease in areas with probable contact between bushpigs and domestic pigs would depend on such information. This study used a molecular and ecological approach to investigate the role of the bushpig in the epidemiology of African swine fever at the wildlife-livestock interface in Uganda. The GPS/GSM tracking collars were used to monitor the movement patterns of free-ranging domestic pigs and bushpigs. Four free-ranging domestic pigs and five bushpigs were collared and their movements ...
The role of the ancestral sylvatic cycle of the African swine fever virus (ASFV) is not well understood in the endemic areas of eastern Africa. We therefore analysed the ASF infection status on samples collected from 51 free-ranging warthogs (Phacocherus africanus) and 1576 Ornithodorus porcinus ticks from 26 independent warthog burrows at a single ranch in Kenya. Abattoir samples from 83 domestic pigs without clinical symptoms, originating from specific locations with no recent reported ASF outbreaks were included in this study. All samples were derived from areas of central Kenya, where ASF outbreaks have been reported in the past. Infection with ASFV was confirmed in 22% of O. porcinus pools, 3.22% of adult warthog serum samples and 49% of domestic pig serum samples by using p72-based PCR. All of the warthog sera were positive for anti-ASFV antibodies, investigated by using ELISA, but none of the domestic pig sera were positive. Twenty O. porcinus-, 12 domestic pig- and three warthogderived ...
African swine fever. African swine fever (ASF) is a highly contagious hemorrhagic disease of pigs that produces a wide range of clinical signs and lesions that closely resemble those of classical swine fever. Infection, with a highly variable virulence, causes, typically 3-15 days later, high fever, reddening of the skin (visible only in pale-skinned pigs), decreased appetite, listlessness, loss of coordination, vomiting, diarrhoea (sometimes bloody) and eye discharges. Mortality rates can be as high as 100% in domestic pigs and wild boar, with death occurring in less than a week. In some cases, sudden death may be the only clinical sign.. The disease was first described after European settlers brought pigs into areas endemic with ASFV and, as such, is an example of an emerging infection. Although ASFV can be adapted to grow in cells from different species, it does not replicate readily in any species other than swine. Fortunately, African swine fever is not a human health threat.. The virus : ...
We describe a horizontal survey of African swine fever virus (ASFV) prevalence and risk factors associated with virus infection in domestic pigs in two contrasting production systems in Kenya. A free range/tethering, low input production system in Ndhiwa District of South-western Kenya is compared with a medium input stall fed production system in Kiambu District of Central Kenya. Analysis of variance (ANOVA) of data derived from cluster analysis showed that number of animals, number of breeding sows and number of weaner pigs were a significant factor in classifying farms in Nhiwa and Kiambu. Analysis of blood and serum samples using a PCR assay demonstrated an average animal level positivity to ASFV of 28% in two independent samplings in South-western Kenya and 0% PCR positivity in Central Kenya. No animals were sero-positive in either study site using the OIE indirect-ELISA and none of the animals sampled exhibited clinical symptoms of ASF. The farms that contained ASFV positive pigs in Ndhiwa ...
TY - ABST. T1 - Detection of African swine fever virus in asymptomatic pigs using FTA cards in Mbeya region, Tanzania. AU - Uttenthal,Åse. AU - Braae,Uffe Christian. AU - Ngowi,Helena Aminel. AU - Rasmussen,Thomas Bruun. AU - Nielsen,Jens. AU - Johansen,Maria Vang. N1 - Oral presentation.. PY - 2012. Y1 - 2012. M3 - Conference abstract in proceedings. SP - 83. EP - 84. BT - IX International Congress of Veterinary Virology. PB - European Society for Veterinary Virology (ESVV). ER - ...
Read "Molecular epidemiology of African swine fever virus studied by analysis of four variable genome regions, Archives of Virology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
African swine fever is highly contagious and nearly 100% fatal to swine herds. It occurs among pigs and wild boars, transmitted by ticks and direct contact between animals. There is no vaccine for the disease, but it does not affect humans.. The first outbreak of African swine fever in East Asia was reported in China in early August 2018. Since then, the deadly virus has spread to all Chinese provinces and regions, as well as to other Asian nations, including Vietnam and the Philippines.. South Korea, Asias fourth-largest economy, does not import any pork products or live pigs from China due to Chinas history of foot-and-mouth disease outbreaks. It mainly imports from the United States and Germany, and pork imports account for about a third of the countrys total pork supplies.. Although this is the first time African swine fever has hit South Korea, an incidence of foot-and-mouth disease was confirmed in March 2018 at a hog farm, the countrys first discovery since February 2017.. South Korea ...
We applied social network analysis to pig trader networks on the Kenya-Uganda border. Social network analysis is a recently developed tool, which is useful for understanding value chains and improving disease control policies. We interviewed a sample of 33 traders about their experiences with trade and African swine fever (ASF), analyzed the networks they generated in purchasing pigs and selling pork and their potential contribution to modulating dissemination of the ASF virus (ASFV). The majority of the traders were aware of clinical signs of ASF and the risk of trade transmitting ASFV. Most said they avoided buying pigs from ASF outbreak villages or sick pigs but their experiences also indicated that inadvertent purchase was relatively common. Traders had early knowledge of outbreaks since they were contacted by farmers who had heard rumours and wanted to sell their pigs to avoid the risk of them dying. Individual traders bought pigs in up to nine villages, and up to six traders operated in a ...
FASINA, Folorunso O. et al. Spatio-temporal patterns and movement analysis of pigs from smallholder farms and implications for African swine fever spread, Limpopo province, South Africa. Onderstepoort j. vet. res. [online]. 2015, vol.82, n.1, pp.01-11. ISSN 2219-0635. http://dx.doi.org/10.4102/ojvr.v82i1.795.. Infectious and zoonotic disease outbreaks have been linked to increasing volumes of legal and illegal trade. Spatio-temporal and trade network analyses have been used to evaluate the risks associated with these challenges elsewhere, but few details are available for the pig sector in South Africa. Regarding pig diseases, Limpopo province is important as the greater part of the province falls within the African swine fever control area. Emerging small-scale pig farmers in Limpopo perceived pig production as an important means of improving their livelihood and an alternative investment. They engage in trading and marketing their products with a potential risk to animal health, because the ...
Microarray technology can be useful for pathogen detection as it allows simultaneous interrogation of the presence or absence of a large number of genetic signatures. However, most microarray assays are labour-intensive and time-consuming to perform. This study describes the development and initial evaluation of a multiplex reverse transcription (RT)-PCR and novel accompanying automated electronic microarray assay for simultaneous detection and differentiation of seven important viruses that affect swine (foot-and-mouth disease virus [FMDV], swine vesicular disease virus [SVDV], vesicular exanthema of swine virus [VESV], African swine fever virus [ASFV], classical swine fever virus [CSFV], porcine respiratory and reproductive syndrome virus [PRRSV] and porcine circovirus type 2 [PCV2 ...
The Mkuze Game Reserve (MGR), in north-eastern KwaZulu-Natal Province, South Africa is an African swine fever virus (ASF) controlled area. In a survey conducted in 1978, ASF prevalence in warthogs and Ornithodoros ticks in MGR was determined to be 2% and 0.06%, respectively. These values, acknowledged as being unusually low compared to other East and southern African ASF-positive sylvatic-cycle host populations, have not been assessed since. The availability of a sensitive PCR-based virus detection method, developed specifically for the sylvatic tampan host, prompted a re-evaluation of ASF virus (ASFV) prevalence in MGR ticks. Of the 98 warthog burrows inspected for Ornithodoros presence, 59 (60.2%) were found to contain tampans and tick sampling was significantly male-biased. Whilst gender sampling-bias is not unusual, the 27% increase in infestation rate of warthog burrows since the 1978 survey is noteworthy as it anticipates a concomitant increase in ASFV prevalence, particularly in light of the high
The cellular secretory pathway is important during the assembly and envelopment of viruses and also controls the transport of host proteins, such as cytokines and major histocompatibility proteins, that function during the elimination of viruses by the immune system. African swine fever virus (ASFV) encodes at least 26 proteins with stretches of hydrophobic amino acids suggesting entry into the secretory pathway (R. J. Yanez, J. M. Rodriguez, M. L. Nogal, L. Yuste, C. Enriquez, J. F. Rodriguez, and E. Vinuela, Virology 208:249-278, 1995). To predict how and where these potential membrane proteins function, we have studied the integrity of the secretory pathway in cells infected with ASFV. Remarkably, ASFV caused complete loss of immunofluorescence signal for the trans Golgi network (TGN) marker protein TGN46 and dispersed the AP1 TGN adapter complex. Loss of TGN46 signal was not due to degradation of TGN46, suggesting redistribution of TGN46 to other membrane compartments. ASFV markedly slowed ...
The Food and Veterinary Board has diagnosed African swine fever (ASF) in pigs on a farm with 3,200 animals in the territory of the Orissaare rural municipality in Saaremaa.
Michael S Denyer and Philip J Wilkinson, Institute for Animal Health, Pirbright Laboratory, Pirbright, UK. African swine fever (ASF) is a highly contagious acute hemorrhagic disease of domestic pigs caused by a large icosahedral DNA virus which produces a wide range of clinical signs. Protective immunity can be stimulated in vivo but classical neutralizing antibodies have not been demonstrated. The complete genome has been sequenced and some proteins that could enable the virus to evade the host immune response have been identified. There is no vaccine.. ...
Since entering the eastern EU at the start of 2014, African swine fever (ASF) has spread locally in the wild boar population, independently of outbreaks in domestic pigs. No correlation between the density of the wild boar population and the case notification in an area has been observed. The source of virus introduction appeared to be the low biosecurity level in backyard farms; yet, direct contact between pigs and wild boar has not been reported. Potential wild boar management strategies aimed at controlling ASF were evaluated. First, the published literature was searched for evidence of changes in wild boar demography after implementing different management strategies. A reduction in a wild boar population of more than 60 % as a result of conventional hunting has not been documented in Europe. Secondly, during a consultation meeting, 30 experts identified different wild boar management tools to indirectly combat ASF spread. In the third step, an epidemiological simulation model was developed, ...
AFRICA - The Food and Agriculture Organization of the United Nations (FAO) has joined with two African organisations to develop a regional strategy for the control of African swine fever (ASF) for the continent.
Abstract: A training and outreach program to increase public awareness of African swine fever (ASF) was implemented by DTRA and the Ministries of Agriculture in Armenia, Georgia, Kazakhstan, and Ukraine. The implementing agency was the company SAFOSO (Switzerland). Integration of this regional effort was administered by subject matter experts for each country. The main teaching effort of this project was to develop a comprehensive regional public outreach campaign through a network of expertise and knowledge for the control and prevention of ASF in four neighboring countries that experience similar issues with this disease. Gaps in disease knowledge, legislation, and outbreak preparedness in each country were all addressed. Because ASF is a pathogen with bioterrorism potential and of great veterinary health importance that is responsible for major economic instability, the project team developed public outreach programs to train veterinarians in the partner countries to accurately and rapidly
Three new outbreaks of African Swine Fever (ASF) have been detected in the Russian Tver region, reports the Rosselkhoznadzor, the Federal Service for Veterinary and Phytosanitary Surveillance. All of them occurred in wild boars, in different parts of the region.
Uganda is a low-income country with the largest pig population in East Africa. Pig keeping has a large potential, commercially and as a tool for poverty reduction, but African swine fever (ASF) is a major hurdle for development of the sector. The objective of this study was to evaluate knowledge, attitudes and... ...
CHINA - As the African swine fever (ASF) situation worsens in many parts of the world, China has become increasingly concerned about the potential introduction of the disease.
The continued advance of African swine fever (ASF) through Eastern European countries has triggered concern amongst pig farmers and governing bodies. Defra has upgraded the threat to the UK from very low to low - meaning the risk is
Keeping African swine fever (ASF) out of Britain is a top priority for the pig sector and a Bpex poster is aimed at helping farmers remind their eastern Eu
Leading researchers from The Pirbright Institute have joined with other European scientists to share knowledge and expertise as part of an international collaboration to prevent the spread of African swine fever (ASF).
Nearly 800 wild boar carcasses infected with African swine fever (ASF) have been found in Estonias forests in 2016, while an additional nearly 700 hunted wild boars have been documented as carrying the disease.
One of the recent outbreaks of African Swine Fever in Russias Krasnodar region has been reported to the World Organization for Animal Health (OIE). In the village of Novonickolayevskaya, over 3,000 pigs had to be culled early August.
China has banned imports of pigs, wild boars and related products from Slovakia to prevent the spread of African swine fever from the European country, China
An outbreak of African swine fever in Poland near the German border has killed 21 wild boar, the agriculture minister said Wednesday.
Veterinary medicines maker ECO Animal Health Group said on Monday its business in China was hit by an outbreak of African swine fever, while the ongoing U.S.-China trade war squeezed margins in the United States.
(Reuters Breakingviews) - African swine fever is nudging China towards peak pork. The outbreak, one of the worst recorded, has sent prices of the meat soaring. That is likely to get worse, even if overall inflation is kept in check, due in part to a cooling economy. It means the disease could encourage a lasting shift among the world
DENMARK - The Danish pig industry is operating a strict security screening to ensure that African Swine Fever is not carried into the country from Russia, writes Chris Harris.
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Phone: (785) 532-4274. E-mail: [email protected] Education: PhD in Biochemistry from University of Kentucky, Lexington, KY.. Area of Specialization: Structural biology and biochemistry of Rift Valley Fever Virus proteins; gene expression analysis in African Swine Fever Virus infection; Next Generation Sequencing data analysis. ...
Take action to stop the spread of African swine fever-Qilu Animal Health Products Co., Ltd-At the 87th OIE General Session, the World Assembly called on countries to consider ASF control as a high priority and the OIE committed to implement a global initiative to better support countries in
Around a quarter of the worlds pigs are expected to die from African swine fever as authorities grapple with a complex disease spreading rapidly in the globalization era, the World Organization for Animal Healths president said Thursday.. A sharp reduction in the worlds pig population would lead to possible food shortages and high pork prices, and it might also cause shortfalls in the many products made from pigs, such as the blood-thinner heparin thats used in people, said Dr. Mark Schipp, the organizations president.. The diseases spread in the past year to countries including China, which has half the worlds pigs, had inflamed a worldwide crisis, Schipp told reporters at a briefing in Sydney.. "I dont think the species will be lost, but its the biggest threat to the commercial raising of pigs weve ever seen," he said. "And its the biggest threat to any commercial livestock of our generation.". African swine fever, fatal to hogs but no threat to humans, has wiped out pig herds in ...
African Swine fever is an endemic disease in sub-Saharan Africa and many other parts of the developing world. It is caused by the African Swine virus that primarily replicates in macrophages and monocytes leading to the impairment of the structure and function of the immune system of the infected organisms. Until now the African Swine epidemic continues to spread despite all efforts to contain it. Thus, there is an objective need for effective, safe and affordable preventive and therapeutic approaches, in particular for effective vaccines, to control and eventually eradicate this disease. Since the characteristic feature of the African Swine virus is to impair the immune system and to cause immune deficiencies in its hosts the development of vaccines and other therapeutic approaches against the African Swine virus has implications for other immune deficiencies or diseases. Several other viruses are also known to cause immunodeficiency-like syndromes in humans, including cytomegalovirus, Epstein ...
African Swine fever is an endemic disease in sub-Saharan Africa and many other parts of the developing world. It is caused by the African Swine virus that primarily replicates in macrophages and monocytes leading to the impairment of the structure and function of the immune system of the infected organisms. Until now the African Swine epidemic continues to spread despite all efforts to contain it. Thus, there is an objective need for effective, safe and affordable preventive and therapeutic approaches, in particular for effective vaccines, to control and eventually eradicate this disease. Since the characteristic feature of the African Swine virus is to impair the immune system and to cause immune deficiencies in its hosts the development of vaccines and other therapeutic approaches against the African Swine virus has implications for other immune deficiencies or diseases. Several other viruses are also known to cause immunodeficiency-like syndromes in humans, including cytomegalovirus, Epstein ...
The African swine fever virus (ASFV) protease that processes the viral polyproteins is required for a late maturational step in virus core assembly and production of infectious progeny virus. On the other hand, studies on ASFV morphogenesis have shown a correlation between proteolytic processing of polyproteins and correct virus assembly, suggesting that the activity of the protease might be modulated during the infection. Indeed, recent studies demonstrated that the protease activity is controlled by two disulfide bridges formed between cysteines C14 and C24 and between C45 and C50. To investigate the mechanism of this redox regulation, we have studied the interaction of the wild type protease and punctual mutants of the involved cysteines to serine with the substrate polyprotein pp62. Our results show, in pull down experiments, the binding of the wild type but not the mutated protease to polyprotein pp62, indicating that the intramolecular disulfide bonds are necessary for the interaction of ...
Poland on Wednesday confirmed its first cases of deadly swine fever in domestic pigs, as the World Trade Organisation reviewed a Russian embargo on EU pork imports imposed over the disease.
African swine fever (ASF) is usually a contagious viral disease of crazy and home pigs that is present in many parts of Africa, Asia and Europe, including Sardinia (Italy). after illness with the modern strain 22653/14 set alongside the traditional stress Nu81.2, although both isolates grew in the same price in both monocytes and monocyte-derived macrophages. Higher cytokine amounts CP-868596 cell signaling in the supernatants of ASFV-infected pig monocytes in comparison to pig macrophages and wild-boar cells had been detected, without distinctions between isolates. Launch African swine fever (ASF) is normally a contagious and frequently fatal viral disease of local pigs and outrageous boar [22] thats currently endemic in lots of sub-Saharan African countries, the Russian Federation, Transcaucasia, some East Europe, and Sardinia [1]. A recently available ASF outbreak was reported in China [8]. There is certainly neither an authorized vaccine nor cure obtainable still, and disease-control ...
P. W. Krug, C. R. Larson, A. C. Eslami, L. L. Rodriguez. THE ability of transboundary animal disease viruses such as foot-and-mouth disease virus (FMDV) to persist and be transmitted on fomites contributes to the spread of disease, with serious consequences for animal health and international trade. Disinfection of surfaces is a key part of biosecurity during outbreaks, but there is no standardised method of disinfection for porous surfaces such as wood, which is commonly used in farm buildings. This study investigated the ability of two disinfectant chemicals to inactivate FMDV and African swine fever virus (ASFV) dried on to a porous wood surface ...
Porcine monocyte-derived macrophages (moMΦ) have been employed as a model cell in numerous studies of the porcine immune system. However, the lack of a standardized method for moMΦ differentiation hampers the comparison of results coming from the use of different laboratory protocols. In this study we compared the use of varying concentrations of autologous plasma (10, 20 and 30% v/v) or recombinant human macrophage-colony stimulating factor (hM-CSF; 50, 100, and 200 ng/ml) to differentiate porcine monocytes into macrophages. Changes in cell morphology and surface marker expression were assessed by confocal microscopy and flow cytometry. Macrophage differentiation was evaluated by analysing TNF-α response to LPS stimulation and determining cytokine secretion patterns under both basal conditions and after classical and alternative activation. The effects of the differentiation methods on metabolic activity and susceptibility to infection with the myelotropic African swine fever virus (ASFV) ...
TAGUM CITY-The City Government of Tagum assured the public that there is no reported swine fever virus in this city, following the concern raised by several sectors over the reported cases in some parts of the country.. Dr. Jesus Edullantes allayed fears of the public and strongly emphasized that the virus has not reached the local hog industry in the city.. Hinged on Administrative Order 04, s-2019 of the Department of Agriculture (DA), the local government unit of Tagum, headed by Mayor Allan Rellon, convened on Friday, August 20, 2019, the African Swine Fever Task Force (ASF-TF) which was created to ensure the continued implementation of precautionary measures relative food safety and food security in view of the reported increasing swine mortalities in the country.. The inter-agency task force, which is chaired by the City Veterinarian, planned to stringently enforce the said measures to ensure that transportation of live animals, meat products and meat by-products is prohibited unless ...
UN2900 Indicative Examples of Infectious Substances Included in Category A UN2900 Infectious substance, affecting animals African swine fever virus...
It is probable that the virus has entered Georgia through imported frozen or processed pig meat. In the past, in some countries swill feeding, in particular swill originating from aircraft and ships, has been incriminated as a major source of infection ...
Pork sales at supermarkets and food stores have increased sharply as more and more customers are opting to buy the meat with clear origins due to the outbreak of African swine fever. According to retailers, the spread of information about the disease has customers worried since pork is a staple food. Thanh Lan of District 1, who was buying pork at Co.opmart Cong Quynh, said for the past month she has only bought the meat at the supermarket. She was relieved when the supermarket told her that its pork was VietGAP certified, she said. A spokesperson for the Saigon Union of Trading Co.operatives (Saigon Co.op) said pork sales at its retail systems, comprising Co.opmart, Co.opXtra and Co.op Food, across the country have risen by 20 per cent on average since the outbreak of African swine fever. They are selling 45-50 tonnes on weekdays and 60-70 tonnes during weekends, it said. Anh Thy, a salesperson at a Vissan store near Thi Nghe Market in HCM Citys Binh Thanh District, told Viet Nam News that ...
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swine fever virus N(pro) protein: has autoproteolytic activity; inhibits double-stranded RNA-mediated apoptosis and IFN-alpha/beta induction; GenBank AF144472
SEJONG -- It is now close to one month since the nations first case of African swine fever was confirmed in Paju, Gyeonggi Province, on Sept. 17.The number of outbreaks of the deadly animal virus came to 13 as of 4 p.m., Oct. 8 -- eight in Gyeonggi Province and five in Incheon. All the affected regions are close to the inter-Korean border: Paju, Gyeonggi Province, with five cases; Yeoncheon, Gyeonggi Prov...
German Agriculture Minister Christian Schmidt is backing an intelligent reduction of Germanys growing wild boar population to prevent a further spread of African Swine Fever (ASF), the Rheinische Post newspaper reported on Friday.
An African swine fever outbreak is threatening Chinas massive pork industry. Angus Gidley-Baird of RaboResearch Food and Agribusiness discusses.
The supply of pork in China may remain tight for the next few years, a leading pig industry expert said recently, citing unprecedented losses due to African swine fever, which has spread around the country since August last year.
SEOUL: South Korea on Tuesday reported its first cases of African swine fever, becoming the latest country hit by the disease that has killed pigs from China to North Korea, pushing up pork prices worldwide.
Pig plague threatens Europe African swine fever , or ASF, is a viral disease that kills almost every pig it infects and is likened to Ebola . It gained a foothold in Georgia in 2007, when contaminated pig meat landed from a ship from South-East Africa and was fed to local pigs. ...
Pig plague threatens Europe African swine fever , or ASF, is a viral disease that kills almost every pig it infects and is likened to Ebola . It gained a foothold in Georgia in 2007, when contaminated pig meat landed from a ship from South-East Africa and was fed to local pigs. ...
RaboResearch Food & Agribusiness published its annual global animal protein outlook. In general, African swine fever (ASF) overwhelms the outlook for 2020 – as it has done during 2019 – and will pull down overall growth, as well as bring uncertainty to all markets.
China produces and consumes two-thirds of the worlds pork, but output is plunging as herds are destroyed to stop African swine fever.
26 September 2000 Unigate blames losses on swine fever UNIGATE has blamed the outbreak of swine fever for preventing its pork processing plant in North Yor
Another case of swine fever was detected in Manta in Cahul district. The virus was confirmed by laboratory analysis after a man announced to the National Agency for Food Safety in the district that he had found his pig dead.Immediately, the emergency comm
Pak1 is required for ASFV entry in Vero cells.A) ASFV activates Pak1 at early times post infection. Cells were infected (MOI 5) and phosphorylation of Pak1 (Thr
EIPA treatment inhibits ASFV entry and infection in Vero cells.A-B) EIPA inhibits ASFV uptake. Cells were pretreated (DMSO or EIPA) and infected (MOI 10) for
Global price cycle, Swine Fever outbreak in S Korea, China bans Dutch food imports, USDA forecasts, EU vets vote for new Spanish and German CSF measures, UK farmers suffer second FMD scare.....
The outbreaks of African Swine Fever in Bulgaria have resulted in more than 100 000 pigs being culled in the northern part of the country, Bulgarian National Television (BNT) said on the evening of August 1.. Estimates from before the outbreak of African Swine Fever put the number of registered pigs in Bulgaria at a maximum 600 000.. The Bulgarian Food Safety Agency has begun checks in small towns in northern Bulgaria to see if farmers have voluntarily got rid of their pigs, the report said.. The deadline for doing so in districts in that part of Bulgaria expired on July 31. Failure to comply means a fine of 100 to 1000 leva (about 50 to 500 euro).. Efforts by veterinary authorities in Rousse, the largest city on Bulgarias Danube border, are currently aimed at controlling the outbreak of African Swine Fever in the town of Byala, where a sick pig was found in a farmyard. In the area, 140 animals will be euthanised at six unregistered small farms.. However, employees of the Regional Food Safety ...
African swine fever is spreading slowly in the Baltic countries and Poland, according to the latest epidemiological data analysed by these Member States and EFSA.. The disease is spreading at about 2 km a month in Latvia and Estonia, and 1 km a month in Lithuania and Poland. In addition, the number of infected animals found among hunted wild boar is very low (up to 3%). The outbreaks in wild boar in the Baltic countries and Poland can therefore be defined as a "small-scale epidemic".. The report covers cases reported between 2014 and 2016.. "This report is the outcome of a fruitful cooperation with Member States. We look forward to continuing investigations on this disease, which has serious socio-economic consequences in affected countries," says Andrea Gervelmeyer, veterinary epidemiologist at EFSA.. The first cases of African swine fever were identified in Lithuania and in eastern Poland at the beginning of 2014. The disease was subsequently reported in Latvia and Estonia. No additional ...
African swine fever virus (ASFV) is a highly contagious disease of pigs that has a near 100% mortality rate. The disease was first reported in Kenya in 1921 and was introduced to the Caucasus region when it spread to Georgia in mid-2007. Since this introduction, ASFV has spread to Armenia, Azerbaijan, Iran, and Russia. From 2007 to 2017, Russia reported more than 1,000 ASFV outbreaks that resulted in approximately 800,000 pigs being killed. From March to October 2017, there were outbreaks of ASFV in Siberia, causing concern that the disease could spread to China. In August 2018, the FAO noted that ASFV strain detected in China was "similar" to the strain detected in Russia in 2017 ...
Main Article. The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.. ...
The U.S. Department of Agricultures (USDA) Animal and Plant Health Inspection Service (APHIS) added Moldova to a list of regions considered affected with African swine fever (ASF). We are taking this action because of the confirmation of ASF in Moldova. ASF is a highly contagious disease of wild and domestic swine that can spread rapidly in swine populations with extremely high rates of morbidity and mortality. A list of regions where ASF exists or is reasonably believed to exist is maintained on the APHIS Web site at https://www.aphis.usda.gov/aphis/ourfocus/animalhealth/animal-and-animal-product-import-information/ct_animal_disease_status. ...
In the latest episode of Contagious Thinking, join CVR PhD student Jack Hirst and postdoc Connor Bamford as they chat with Dr Charles Masembe (follow him on Twitter:@cmasembe10) about his work on some of Africas most important animal viruses.. Charles works currently on a virus called African swine fever virus (ASFV), which causes a deadly disease in domestic pigs that can cause great economic and political turmoil in affected regions. ASFV is a fascinating large DNA virus that is spread by wild pigs and the ticks that feed on them. The virus can move between the wild pigs and farmed domestic pigs. Understanding this movement is a major focus of Charles work.. Charles is a veterinarian and molecular epidemiologist by training and is an associate professor at the College of Natural Sciences at Makerere University in Uganda. He is working in a collaboration with scientists at the CVR to sequence ASFV samples from pigs across Uganda. His work is funded by a recently awarded Wellcome Trust ...
A total of 289,038 reads with an average length of 175 nucleotides was obtained. After filtering for length and repeat content, 190,706 reads remained. Seventy-seven percent of the reads were assembled into contigs. Both BLASTN and BLASTX analyses gave similar results. Subsequently, the results that follow are from the BLASTN analysis.. For 62% of all sequences, there was no significant match within GenBank as defined by the above criteria. Among the sequences assigned to a taxon, 52%, whether DNA or RNA, mapped to the domestic pig host (Sus scrofa). Thirty six percent of the sequences also exhibited similarity with other mammalian genomes (17% to the family Bovidae and 6.5% to human); these additional matches were most likely a consequence of the currently incomplete status of the porcine genome.. A small proportion (6.2%) of the sequences mapped to DNA and RNA viruses. For the DNA searches, besides African swine fever virus, which was identified in all pools, Torque teno viruses (TTVs) were ...
It is no small matter to own a pig in Haiti. With very little hard currency in the countryside, pigs act as living savings accounts and are often bartered for other products or wares. One pig can be traded for a years education for two children. In fact, pigs comprise 30 percent of the peasantrys income. In late 1978, when the outbreak of African Swine Fever (ASF) spread to Haiti, the peasantry was devastated. In the next four years, the Haitian government, spurred by the U.S. and Canadian governments, slaughtered every pig on the island to stymie the spread of the fever. African Swine Fever, a virus for which there is neither vaccination nor medication, made its way from Europe or Africa to the Dominican Republic, and later spread to Haiti. The disease, which decimates swine populations, endangers neither humans nor other animals. Even the contaminated meat, if the animals were slaughtered under proper conditions, is perfectly edible. When AFS first made its appearance in the Dominican ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
The state service of Ukraine on issues of food safety and consumer protection (state foods and consumer service) and the national police in the near future will
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AMES, Iowa - This years Iowa Swine Day will serve pork producers by offering expert speakers who will address current issues affecting the industry. Some of the topics will include the status of and response to African Swine Fever, what makes a biosecurity program successful, improving company culture, precision pork production, and feeding the high-producing sow. The event will be hosted in Ames at Iowa State University on Thursday, June 27 by the Iowa Pork Industry Center.. "Iowa Swine Day is a great opportunity to learn, network, and build relationships within the swine industry," said Jason Ross, Iowa Swine Day committee chair. "The topics being discussed at this years event are a result of direct input from pork producers who let us know what topics are important to them.". The morning session will feature Dr. Frank Mitloehner from the University of California-Davis, who will explore how improvements in livestock production efficiencies, genetics, nutrition, and veterinary care can help ...
Introduction. Classical and African swine fever (CSF, ASF) are the two most feared diseases of swine worldwide. Both are characterised by high mortality and are transboundary diseases that can have devastating effects on livelihoods that depend on pig production (Costard et al. 2009; Moennig 2000). Although they are caused by completely unrelated viruses, the pathogenesis of the two diseases is similar, therefore the clinical and pathological manifestations are strikingly alike (Moennig 2000; Penrith, Thomson & Bastos 2004a). CSF is caused by a single-stranded RNA virus of the genus Pestivirus, family Flaviviridae, while ASF is caused by a large, double-stranded DNA virus that was only allocated to its own genus, Asfivirus, the only member of the family Asfarviridae, in 1998 (Dixon et al. 2005). Both viruses affect only members of the pig family (Suidae) (Moennig 2000; Plowright, Thomson & Neser 1994). Both are highly contagious diseases in pigs and their ancestors, the Eurasian wild boar (Sus ...
HANOI, Vietnam (AP) - Asian nations are scrambling to contain the spread of highly contagious African swine fever, with Vietnam culling 2.6 million pigs and China reporting more than a million dead in an unprecedentedly huge epidemic some fear is out of control.
POLAND - Following Russias ban on imports of pork from Poland on the grounds of a risk of African Swine Fever, the Polish Minister of Agriculture has announced upcoming meetings with future trading partners in Asia.
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Daily New York Times connects, in a wide investigative article, the nowadays swine flu wave and the one that affected Romanian farms in 2007. That particular strain affects only hogs, but - hotnews, news, articles, press review, politics, economics, sport
The veterinary department said that 57 cases of ASF have been registered in seven regions since the start of 2012: 23 in Krasnodar territory, 19 in Tver, 11 in Volgograd region and one-off cases in Karelia and Kalmykia, Rostov and Yaroslavl regions.. The ASF situation worsened between June 19 and September 8. During this time 50 cases were identified in five regions - 20 in Krasnodar territory, 19 in Tver region, 9 in Volgograd and one each in Rostov and Yaroslavl regions. So far two cases of ASF have been eliminated in household farms, so there are now 48 cases of infection.. Despite a bank, household and small farms continue to feed pigs with fodder containing raw pig or wild boar slaughter products. "A major risk factor is that farm owners and managers are still underestimating the danger of the spread of ASF and are breaching biological protection of industrial zone regimes," the report says.. Fyodorov recommended that the example at Krasnodar territory be considered where careless farmers ...
At the moment I work in the [[ASFV]] laboratory at CBM. I have gained my PhD working in ASFV DNA Repair and now I am in my first post-doc in the same lab. Currently we are very interested in the role in vivo of the viral BER system, specially the polβ-like DNA repair polymerase (named pol X ...
At the moment I work in the [[ASFV]] laboratory at CBM. I have gained my PhD working in ASFV DNA Repair and now I am in my first post-doc in the same lab. Currently we are very interested in the role in vivo of the viral BER system, specially the polβ-like DNA repair polymerase (named pol X ...
Canadian hogs, Suspected Swine Fever outbreak in Japan, Americans eat too much meat say cancer scientists, McDonalds sued over use of trans fat, Global price cycle, WTO members urged to meet deadline ...../
Classical swine fever (CSF) has caused significant economic losses in industrialized pig production, and is still present in some European countries. Recent CSF outbreaks in Europe were mainly associated with strains of genogroup 2 (subgroup 2.3). Although there are extensive datasets regarding 2.3 strains, there is very little information available on longer fragments or whole classical swine fever virus (CSFV) genomes. Furthermore, there are no detailed analyses of the molecular epidemiology of CSFV wild boar isolates available. Nevertheless, complete genome sequences are supportive in phylogenetic analyses, especially in affected wild boar populations. Here, German CSFV strains of subgroup 2.3 were fully sequenced using two different approaches: (i) a universal panel of CSFV primers that were developed to amplify the complete genome in overlapping fragments for chain-terminator sequencing; and (ii) generation of a single full-length amplicon of the CSFV genome obtained by long-range RT-PCR ...
The inspectors of the Latvian Food and Veterinary Service this week found 14 wild boars killed by African swine fever (ASF), including in two regions in central Latvia that had been hit by the disease first time, the veterinary authority said LETA.
Asia is home to 4.6 billion more than half of the planets population and most of them rely heavily on a pork diet. China with a population of almost 1.5 billion people have suffered the biggest impact of African Swine Fever, more than 55% of Chinese pigs - hundreds of millions of animals - have now been lost, and the result has been a chronic shortage of pork and rocketing price. The disease is eating up pig populations of South East Asia. Vietnam and the Philippines have seen some of the worst outbreaks in the region. The latest country to report an outbreak of African swine fever (ASF) is Indonesia, specifically in the province of North Sumatra, the Food and Agriculture Organization of the United Nations confirmed on Dec. 12. The disease has also been detected in Mongolia, Cambodia, South Korea, North Korea, Myanmar and East Timor, according to the UN Food and Agriculture Organisation. Outside of Asia, the OIE said the disease is also present in parts of Eastern Europe and sub-Saharan Africa ...
Cytopathic effect of classical swine fever virus NS3 protein on PK-15 cells.: In order to further research the relationship between classical swine fever virus
In the Ramenskoye district of the Moscow region recorded outbreak of African swine fever, reports "Interfax".. Specialists of the Rosselkhoznadzor found in the enterprise "agro Konstantinovo" the violation of a number of veterinary standards and requirements. Absent heat-treatment of the feed, worked a disinfection barrier.. From African swine fever (ASF) has killed 17 adult animals and 24 pigs. Earlier, three infected pigs were sold to private hands, the buyer did not know about the disease.. On the farm goes the extra sanitization and destruction of livestock. Infected animals will be killed in a bloodless manner. Because of the virus, the enterprise may lose more than 200 animals.. This year the Rosselkhoznadzor expects more than 300 outbreaks in Russia. Most likely the risk of ASF in Mordovia, Udmurtia, Mari El, Tatarstan, the Tver and Kostroma regions.. Last week the head of the Ministry Alexander Tkachev said that the loss of the Russian farms from Achs for 10 years amounted to more than 5 ...
Read "Induction of immune responses in mice and pigs by oral administration of classical swine fever virus E2 protein expressed in rice calli, Archives of Virology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Challenge of Pigs with Classical Swine Fever Viruses after C-Strain Vaccination Reveals Remarkably Rapid Protection and Insights into Early Immunity. . Download books free in pdf. Online library with books, university works and thousands of documents available to read online and download.
The early identification of classical swine fever epizootics is hampered by difficulties in recognising early signs of infection, due to a lack of specific clinical signs. In addition many textbook descriptions of CSF are based on observations of disease caused by historic, mainly genotype 1, strains. Our objective was to improve our knowledge of the diverse range of signs that different CSFV strains can cause by characterising the experimental infection of domestic pigs with both a recent strain of CSFV and a divergent strain. Conventional pigs were inoculated with a genotype 2.1 isolate, that caused an outbreak in the UK in 2000, and a genotype 3.3 strain that is genetically divergent from European strains. This latter strain is also antigenically distinct as it is only poorly recognised by the CSFV-specific monoclonal antibody, WH303. Transmission was monitored by use of in-contact animals. Clinical, virological and haematological parameters were observed and an extended macro- and ...
The domestic swine fever virus C strain was purified by USA, Japan, local swine fever, but the domestic swine fever epidemic is still serious. Control of classical swine fever, the industry has different views, many people think is the prob
This study was carried out to estimate the prevalence and related risk factors of porcine cysticercosis (caused by Taenia solium) and African swine fever (ASF) in domestic pigs, and assesses the state of pork inspection ...
The aim of this paper is to evaluate the African swine fever (ASF) outbreak that began in 1978 in Paracambi municipality, Rio de Janeiro State, Brazil, and the steps taken by the Brazilian authorities to eradicate the disease. The presence of ASF in the country was confirmed by isolating the virus, and its pathogenicity was certified by the laboratory of the Plum Island Disease Center, New York, United States. Even before the laboratory results became available, the Brazilian Agriculture Ministry declared an Animal Health Emergency, in which the official Veterinary Services adopted rapid control measures to restrain and eradicate the disease. These control measures contributed to the reorganisation of the national swine industry and stimulated the use of high-technology production techniques, as well as an improvement in herd health consciousness. All this contributed to Brazil becoming the largest meat exporter in the world. ...
Citation: Risatti, G.R., Holinka, L.G., Fernandez-Sainz, I., Carillo, C., Kutish, G.F., Lu, Z., Tulman, E.R., Rock, D.L., Borca, M.V. Mutations in the Carboxi Terminal Region of E2 Glycoprotein of Classical Swine Fever Virus is Responsible for Viral Attenuation in Swine. Conference of Research Workers in Animal Disease (CRWAD) annual meeting, Chicago, IL, December 3-5, 2006, page 138. Interpretive Summary: Technical Abstract: We have reported that chimeric virus 319.1 virus containing the E2 glycoprotein gene from Classical Swine Fever Virus (CSFV) vaccine strain CS with the genetic background of virulent CSFV strain Brescia (BIC virus) was attenuated in pigs. To identify the amino acids mediating 319.1 virus attenuation a series of chimeric viruses containing CS E2 residues in the context of the Brescia strain were constructed. Chimera 357 virus, containing CS E2 residues 691 to 881 of CSFV polyprotein was virulent, while chimera 358 virus, containing CS E2 residues 882 to 1064, differing in ...
hybridization patterns, the distinct genotypes of CSFV Brecent years. It can detect different pathogens in a could be differentiated. The results showed that the piece of chip and can differentiate the various CSFV amplified by primer CP5.6 could be classified into genotypes in the same species. In 2003, a bio-chip three genotypes, including the native, invaded, and diagnosis system was established by using classical lapinized hog cholera vaccine virus by hybridization swine fever virus (CSFV) as a model. Nucleotide with oligonucleotide probe. No cross reaction was sequences of classical swine fever virus were collected found when the bio-chip was hybridized with bovine from the GenBank, and the domestic CSFV field strains diarrhea disease virus which was closely related to the were sequenced. These sequence data were analyzed with a computer software by sequence alignment and apair of universal primers, which could amplify different News source: National Veterinary Research Insti- ...
Classical swine fever (CSF) is a highly contagious swine disease caused by classical swine fever virus (CSFV). Previously, we demonstrated that rAdV-SFV-E2, an adenovirus-delivered, Semliki Forest virus replicon-vectored marker vaccine against CSF, is able to protect pigs against lethal CSFV challenge. From an economical point of view, it will be beneficial to reduce the minimum effective dose of the vaccine. This study was designed to test the adjuvant effects of Salmonella enteritidis-derived bacterial ghosts (BG) to enhance the protective immunity of rAdV-SFV-E2 in pigs. Groups of 5-week-old pigs (n = 4) were immunized intramuscularly twice with 105 median tissue culture infective doses (TCID50) rAdV-SFV-E2 combined with 1010 colony forming units (CFU) BG, 106 or 105 TCID50 rAdV-SFV-E2 alone or 1010 CFU BG alone at an interval of 3 weeks, and challenged with the highly virulent CSFV Shimen strain at 1 week post-booster immunization. The results show that the pigs inoculated with 105 TCID50 rAdV-SFV
November 24, 2010 - The U.S. Department of Agricultures Animal and Plant Health Inspection Service (APHIS) is amending its regulations governing the importation of certain animals and animal products by adding the Brazilian State of Santa Catarina to the list of regions we recognize as free of foot-and-mouth disease (FMD), rinderpest, swine vesicular disease (SVD), classical swine fever (CSF) and African swine fever (ASF). APHIS is also adding Santa Catarina to the list of regions that are subject to certain import restrictions on meat and meat products because of their proximity to or trading relationships with rinderpest- or FMD-affected countries. These actions will update the disease status of Santa Catarina with regard to FMD, rinderpest, SVD, CSF and ASF while continuing to protect the United States from an introduction of those diseases by providing additional requirements for live swine, pork meat, pork products, live ruminants, ruminant meat and ruminant products imported into the ...
Classical Swine Fever Vaccines Industry including (both global and regions) Market Size (both volume - Unit and value - million USD), Market Share, Production data, Consumption data, Trade data, Price - USD/Unit, Cost, Gross margin, Analysis, Forecast etc.. The report offers a holistic overview of the Classical Swine Fever Vaccines market with the help of application segments and geographical regions that govern the market currently. Further, the report delves deep into the value chain of the Classical Swine Fever Vaccines market so as to emerge with information specific areas that hold high revenue-generating potential. With the Classical Swine Fever Vaccines market having undergone certain inherent shifts in the past decades, the report discusses how these changes will impact the future.. Get Free Sample Report: https://www.fiormarkets.com/report-detail/98205/request-sample. Moreover, the report also provides a realistic picture of the state of both traditional and emerging markets. The ...
July 3, 2012 - Representatives of federal agencies, the biologics industry and academia are invited to participate in a Workshop to discuss state-of-the-art measures for vaccine and diagnostic tool development for significant transboundary animal diseases. The Workshop will be held September 17-19, 2012 in Ames Iowa. Scientists are invited to submit abstracts featuring novel research to diagnose and control important transboundary animal diseases. Internationally recognized experts will discuss state of the art research for the following diseases: highly pathogenic avian influenza; exotic Newcastle disease; foot and mouth disease; Rift Valley fever; Nipah and Hendra viruses; African swine fever; classical swine fever; Heartwater; Q fever; Ebola; and Schmallenberg virus. To register or submit abstracts for poster presentations, please visit http://www.cfsph.iastate.edu/Meetings/2012-vaccines-and-diagnostics-for-transboundary-animal-diseases.php by August 10. The cost to attend the Workshop is ...
Purified Recombinant Yellow Fever Virus NS1 Protein, His-tagged from Creative Biomart. Recombinant Yellow Fever Virus NS1 Protein, His-tagged can be used for research.
The current yellow fever outbreak in Brazil prompted widespread yellow fever virus (YFV) vaccination campaigns, imposing a responsibility to distinguish between vaccine- and wild-type YFV-associated disease. We developed novel multiplex real-time reverse transcription PCRs that differentiate between vaccine and American wild-type YFV. We validated these highly specific and sensitive assays in an outbreak setting.
Contents Health-Defined Animals 270 Immunity in Health-Defined Animals 272 Virus Infections During Gestation 275 Respiratory Infections 279 Influenza 279 Ascariasis enhancement of respiratory infections 280 Virus pneumonia of pigs 281 Infectious atrophic rhinitis of swine 282 Porcine inclusion body rhinitis 283 Infectious bovine rhinotracheitis 283 Bovine myxovirus parainfluenza 284 Infectious bovine keratoconjunctivitis 284 Enteric Infections 285 Swine polio-encephalomyelitis viruses 285 Transmissible gastroenteritis of swine 286 Berans swine enterovirus 287 Bovine virus diarrhea 287 Systemic Diseases 288 Hog cholera 288 African swine fever 290 Nebraska University disease 290 Swine edema disease 291 Exudative epidermitis of swine 292 Foot-and-mouth disease and rinderpest 293

African swine fever virus, illustration - Stock Image F016/8841 - Science Photo LibraryAfrican swine fever virus, illustration - Stock Image F016/8841 - Science Photo Library

This virus is a member of the iridovirus group that causes African swine fever. Unlike other DNA- containing vertebrate viruses ... African swine fever virus, illustration. This virus is a member of the iridovirus group that causes African swine fever. Unlike ... Keywords: 3 dimensional, 3d, african swine fever virus, artwork, biological, biology, cgi, digitally generated, dna virus, ... swine, three dimensional, viral, virion, virology, virus ... African swine fever virus, illustration. F016/8841 Royalty Free ...
more infohttp://www.sciencephoto.com/media/782691/view

Molecular epidemiology of African swine fever virus studied by analysis of four variable genome regions, Archives of Virology |...Molecular epidemiology of African swine fever virus studied by analysis of four variable genome regions, Archives of Virology |...

"Molecular epidemiology of African swine fever virus studied by analysis of four variable genome regions, Archives of Virology" ... The African swine fever virus proteins p54 and p30 are involved in two distinct steps of virus attachment and both contribute ... Identification of the principal serological immunodeterminants of African swine fever virus by screening a virus cDNA library ... Molecular epidemiology of African swine fever virus studied by analysis of four variable genome regions. Nix, R. J.; Gallardo, ...
more infohttps://www.deepdyve.com/lp/springer_journal/molecular-epidemiology-of-african-swine-fever-virus-studied-by-Cx3EzKQOTl

Comparison of African swine fever virus prevalence and risk in two contrasting pig-farming systems in South-west and Central...Comparison of African swine fever virus prevalence and risk in two contrasting pig-farming systems in South-west and Central...

We describe a horizontal survey of African swine fever virus (ASFV) prevalence and risk factors associated with virus infection ... Comparison of African swine fever virus prevalence and risk in two contrasting pig-farming systems in South-west and Central ... Comparison of African swine fever virus prevalence and risk in two contrasting pig-farming systems in South-west and Central ... The data therefore indicated a potential role for the bushpig in virus transmission in South-western Kenya, but there was no ...
more infohttps://cgspace.cgiar.org/handle/10568/32847

Pig traders networks on the Kenya-Uganda border highlight potential for mitigation of African swine fever virus transmission...Pig traders' networks on the Kenya-Uganda border highlight potential for mitigation of African swine fever virus transmission...

Pig traders networks on the Kenya-Uganda border highlight potential for mitigation of African swine fever virus transmission ... Pig traders networks on the Kenya-Uganda border highlight potential for mitigation of African swine fever virus transmission ... We interviewed a sample of 33 traders about their experiences with trade and African swine fever (ASF), analyzed the networks ... generated in purchasing pigs and selling pork and their potential contribution to modulating dissemination of the ASF virus ( ...
more infohttps://dspacetest.cgiar.org/handle/10568/80427

African swine fever viruses with two different genotypes, both of which occur in domestic pigs, are associated with ticks and...African swine fever viruses with two different genotypes, both of which occur in domestic pigs, are associated with ticks and...

African swine fever viruses with two different genotypes, both of which occur in domestic pigs, are associated with ticks and ... African swine fever viruses with two different genotypes, both of which occur in domestic pigs, are associated with ticks and ... The role of the ancestral sylvatic cycle of the African swine fever virus (ASFV) is not well understood in the endemic areas of ... The data from this and earlier studies suggest transfer of viruses of at least two different p72 genotypes, from wild to ...
more infohttps://cgspace.cgiar.org/handle/10568/35350

The role of the bushpigs in the epidemiology of African swine fever at the wildlife-livestock interfaces in Uganda | RUFORUM...The role of the bushpigs in the epidemiology of African swine fever at the wildlife-livestock interfaces in Uganda | RUFORUM...

African swine fever is a devastating hemorrhagic fever of pigs, caused by the African swine fever virus (ASFV). In Africa, the ... The role of the bushpigs in the epidemiology of African swine fever at the wildlife-livestock interfaces in Uganda. You are ... used a molecular and ecological approach to investigate the role of the bushpig in the epidemiology of African swine fever at ... presence of a sylvatic cycle involving warthogs and soft ticks means that the risk of introduction of ASFV into domestic swine ...
more infohttp://repository.ruforum.org/documents/role-bushpigs-epidemiology-african-swine-fever-wildlife-livestock-interfaces-uganda

African swine fever | ari.info | ari.infoAfrican swine fever | ari.info | ari.info

The virus : one of a kind. The virus belongs to the Asfarviridae family - also known as the African swine fever-like viruses - ... African swine fever. African swine fever. African swine fever (ASF) is a highly contagious hemorrhagic disease of pigs that ... it does not replicate readily in any species other than swine. Fortunately, African swine fever is not a human health threat. ... The overarching piece of legislation providing the tool for the control of African swine fever in the EU is Council Directive ...
more infohttp://www.animalresearch.info/en/medical-advances/veterinary-medicine/african-swine-fever/

South Korea on highest alert after African swine fever found - InteraksyonSouth Korea on highest alert after African swine fever found - Interaksyon

The first outbreak of African swine fever in East Asia was reported in China in early August 2018. Since then, the deadly virus ... African swine fever is highly contagious and nearly 100% fatal to swine herds. It occurs among pigs and wild boars, transmitted ... Although this is the first time African swine fever has hit South Korea, an incidence of foot-and-mouth disease was confirmed ... "We will make all efforts to stop the spread of African swine fever through swift disinfection measures," Kim said. ...
more infohttp://www.interaksyon.com/politics-issues/2019/09/17/155032/south-korea-on-highest-alert-after-african-swine-fever-found/

PPT - Hog Cholera (Classical Swine Fever) PowerPoint Presentation - ID:113381PPT - Hog Cholera (Classical Swine Fever) PowerPoint Presentation - ID:113381

Definition of hog cholera:. highly contagious viral disease of swine can cause acute, chronic, or congenital disease considered ... Classical Swine Fever). Sandra Axiak and Carolin Winter. ... African Swine Fever *distinguished from hog cholera only via ... experience life-long viremia and persistently shed the virus *have few clinical signs for the first few months of life, then ... Classical Swine Fever). Sandra Axiak and Carolin Winter. Definition of hog cholera:. highly contagious viral disease of swine ...
more infohttps://www.slideserve.com/flora/hog-cholera

China finds African swine fever virus in pigs transported to Guangxi - ReutersChina finds African swine fever virus in pigs transported to Guangxi - Reuters

China detected African swine fever in pigs being transported to Guangxi region from outside provinces, the agriculture ministry ... The deadly African swine fever disease is much more severe than officially reported in China, leading to the death or killing ... BEIJING (Reuters) - China detected African swine fever in pigs being transported to Guangxi region from outside provinces, the ...
more infohttps://www.reuters.com/article/us-china-swinefever/china-finds-african-swine-fever-virus-in-pigs-transported-to-guangxi-idUSKCN1UY100

Hairpin loop structure of African swine fever virus DNA.  - PubMed - NCBIHairpin loop structure of African swine fever virus DNA. - PubMed - NCBI

The ends of African swine fever virus genome are formed by a 37 nucleotide-long hairpin loop composed, almost entirely, of ... Hairpin loop structure of African swine fever virus DNA.. González A, Talavera A, Almendral JM, Viñuela E. ... The hairpin loops of African swine fever and vaccinia virus DNAs had no homology, but both DNAs had a 16 nucleotide-long ... An analysis of African swine fever virus replicating DNA showed head-to-head and tail-to-tail linked molecules that may be ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/3763393?dopt=Abstract

Genetic characterization of African swine fever virus in Cameroon, 2010-2018.Genetic characterization of African swine fever virus in Cameroon, 2010-2018.

... is a highly lethal haemorrhagic disease in domestic and wild swine that has acquired great importance in sub-Saharan Africa ... African swine fever virus evasion of host defences.. African swine fever virus causes a haemorrhagic fever in domestic pigs and ... African swine fever: an unprecedented disaster and challenge to China.. African swine fever (ASF), caused by African swine ... Summary of "Genetic characterization of African swine fever virus in Cameroon, 2010-2018.". African swine fever (ASF) is a ...
more infohttps://www.bioportfolio.com/resources/pmarticle/2331236/Genetic-characterization-of-African-swine-fever-virus-in-Cameroon-2010-2018.html

Canary Database: Browse by Exposure: African Swine Fever VirusCanary Database: Browse by Exposure: African Swine Fever Virus

Browse by Exposure: African Swine Fever Virus (1 article). % of records by year: 1965 2017 ...
more infohttp://canarydatabase.org/browse/exposure/1753

African swine fever virus isolate, Georgia, 2007African swine fever virus isolate, Georgia, 2007

... Rowlands, Rebecca J.; Michaud, Vincent; Heath, Livio Edward; Hutchings, Geoff ... African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed ... isolates to establish the genotype of the virus. Sequences were obtained from 4 genome regions, including part of the gene ... from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF virus (ASFV) ...
more infohttps://repository.up.ac.za/handle/2263/10192

African swine fever virus - WikipediaAfrican swine fever virus - Wikipedia

African swine fever virus (ASFV) is the causative agent of African swine fever (ASF). The virus causes a haemorrhagic fever ... In July, 3 farms discovered African swine fever in Estonia. [...] African swine fever spreads to farmed pigs, 500 animals to be ... Viruses portal Animal viruses Denyer, M. S.; Wilkinson, P. J. (1998). "African Swine Fever". Encyclopedia of Immunology. p. 54 ... 2008). "African Swine Fever Virus". Animal Viruses: Molecular Biology. Caister Academic Press. ISBN 978-1-904455-22-6. Dixon, L ...
more infohttps://en.wikipedia.org/wiki/African_swine_fever_virus

Developing Genetic Tools to Manipulate African Swine Fever Virus and Generate Attenuated Strains | J. Craig Venter InstituteDeveloping Genetic Tools to Manipulate African Swine Fever Virus and Generate Attenuated Strains | J. Craig Venter Institute

ASF is caused by a large DNA virus, African swine fever virus (ASFV), and there is currently no vaccine against it. A major ... Developing Genetic Tools to Manipulate African Swine Fever Virus and Generate Attenuated Strains. ... Developing Genetic Tools to Manipulate African Swine Fever Virus and Generate Attenuated Strains. ... Developing Genetic Tools to Manipulate African Swine Fever Virus and Generate Attenuated Strains ...
more infohttps://www.jcvi.org/developing-genetic-tools-manipulate-african-swine-fever-virus-and-generate-attenuated-strains

K-State Researchers Work to Stay Ahead of African Swine Fever Virus | Farms.comK-State Researchers Work to Stay Ahead of African Swine Fever Virus | Farms.com

Read K-State Researchers Work to Stay Ahead of African Swine Fever Virus in addition to hundreds of recent farming and ... "African Swine Fever virus is a terrible disease that affects only swine," said Cassie Jones, a swine nutritionist with K-State ... K-State researchers currently are studying the African Swine Fever virus in collaboration with Megan Niederwerder, Steve Dritz ... Now, that work may help to fend off the threat from the African Swine Fever virus. ...
more infohttps://www.farms.com/news/k-state-researchers-work-to-stay-ahead-of-african-swine-fever-virus-139443.aspx

African swine fever virus can survive in vacuum-packed pork products - 
		
		FluTrackers News and Information
	African swine fever virus can survive in vacuum-packed pork products - FluTrackers News and Information

... www.taipeitimes.com/News/lang/archives/2018/12/26/2003706772 African swine fever virus can survive in vacuum-packed pork ... African swine fever virus can survive in vacuum-packed pork products. 阷靣洳豨瘙旇実禾帯肄哃 誫仧炷眣穻匇裙尰沗亄. As African swine fever (ASF) ... African swine fever virus can survive in vacuum-packed pork products December 25th, 2018, 12:39 PM. ... African swine fever virus can survive in vacuum-packed
more infohttps://flutrackers.com/forum/forum/asia/804189-african-swine-fever-virus-can-survive-in-vacuum-packed-pork-products

Africa Swine Fever Virus Genome Sequencing to underpin Control | International Livestock Research InstituteAfrica Swine Fever Virus Genome Sequencing to underpin Control | International Livestock Research Institute

Africa Swine Fever Virus Genome Sequencing to underpin Control. Africa Swine Fever Virus Genome Sequencing to underpin Control ... western and southern Africa. Currently there is no reliable data on total numbers of farmers affected in Africa; this project ... Whats new about this project for Africa is that it combines social and economic research with biological surveillance of viral ... Biosciences eastern and central Africa, Commonwealth Scientific and Industrial Research Organisation, Australia ...
more infohttps://www.ilri.org/node/1343

Molecular Characterization of African Swine Fever Virus, China, 2018 - Volume 24, Number 11-November 2018 - Emerging Infectious...Molecular Characterization of African Swine Fever Virus, China, 2018 - Volume 24, Number 11-November 2018 - Emerging Infectious...

We subjected a virus from an African swine fever-positive pig sample to phylogenetic analysis. This analysis showed that the ... an outbreak of African swine fever in pigs was reported in China. ... an outbreak of African swine fever in pigs was reported in China. We subjected a virus from an African swine fever-positive pig ... Malogolovkin A, Burmakina G, Tulman ER, Delhon G, Diel DG, Salnikov N, et al. African swine fever virus CD2v and C-type lectin ...
more infohttps://wwwnc.cdc.gov/eid/article/24/11/18-1274_article

Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three...Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three...

Nuclear export of African swine fever virus p37 protein occurs through two distinct pathways and is mediated by three ... Nuclear Export of African Swine Fever Virus p37 Protein Occurs through Two Distinct Pathways and Is Mediated by Three ... Nuclear Export of African Swine Fever Virus p37 Protein Occurs through Two Distinct Pathways and Is Mediated by Three ... Nuclear Export of African Swine Fever Virus p37 Protein Occurs through Two Distinct Pathways and Is Mediated by Three ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/16415017

Comparative Analysis of Whole-Genome Sequence of African Swine Fever Virus Belgium 2018/1 - Volume 25, Number 6-June 2019 -...Comparative Analysis of Whole-Genome Sequence of African Swine Fever Virus Belgium 2018/1 - Volume 25, Number 6-June 2019 -...

The high-coverage sequence revealed 15 differences compared with an improved African swine fever virus Georgia 2007/1 sequence ... We analyzed the whole-genome sequence of African swine fever virus Belgium 2018/1. The strain fits into the European genotype ... Linden A, Licoppe A, Volpe R, Paternostre J, Lesenfants C, Cassart D, et al. Summer 2018: African swine fever virus hits north- ... In September 2018, the African swine fever virus (ASFV) was introduced into Belgium (3,4); as of April 28, 2019, 719 cases have ...
more infohttps://wwwnc.cdc.gov/eid/article/25/6/19-0286_article

Migration of Mitochondria to Viral Assembly Sites in African Swine Fever Virus-Infected Cells | Journal of VirologyMigration of Mitochondria to Viral Assembly Sites in African Swine Fever Virus-Infected Cells | Journal of Virology

Virus-Cell Interactions. Migration of Mitochondria to Viral Assembly Sites in African Swine Fever Virus-Infected Cells. Gema ... Migration of Mitochondria to Viral Assembly Sites in African Swine Fever Virus-Infected Cells ... Migration of Mitochondria to Viral Assembly Sites in African Swine Fever Virus-Infected Cells ... Migration of Mitochondria to Viral Assembly Sites in African Swine Fever Virus-Infected Cells ...
more infohttps://jvi.asm.org/content/72/9/7583/article-info

Luncheon meat seized at Clark airport tainted with African swine fever virusLuncheon meat seized at Clark airport tainted with African swine fever virus

... The Bureau of Animal Industry says its findings ... This brand of luncheon meat tests positive for African swine fever virus, according to the Philippine Bureau of Animal Industry ... "The detection of the virus in seized products does not change Philippines African swine fever-free status," she said. ... returning Filipino at the Clark International Airport in Pampanga in March are contaminated with the African swine fever virus ...
more infohttps://www.rappler.com/nation/233015-canned-goods-tainted-african-swine-fever-virus-clark-airport

Inducible Gene Expression from African Swine Fever Virus Recombinants: Analysis of the Major Capsid Protein p72 | Journal of...Inducible Gene Expression from African Swine Fever Virus Recombinants: Analysis of the Major Capsid Protein p72 | Journal of...

African swine fever virus (ASFV), the only known member of the genus "African swine fever-like viruses" (25), is the causative ... 1987) Molecular biology of African swine fever virus. in African swine fever. ed Becker Y. (Martinus Nijhoff Publishing, Boston ... 1995) African swine fever-like viruses. Virus taxonomy: classification and nomenclature of viruses. Arch. Virol. 10(Suppl.):92- ... 1986) Monoclonal antibodies of African swine fever virus: antigenic differences among field virus isolates and viruses passaged ...
more infohttps://jvi.asm.org/content/72/4/3185?ijkey=263a5c2069a7640bb9103e39c79f9d325bb0898a&keytype2=tf_ipsecsha
  • Comparison of the size of products generated by polymerase chain reaction (PCR) from four different genome regions, within the B602L and KP86R genes and intergenic regions J286L and BtSj, placed 43 closely related isolated from Europe, the Caribbean, West and Central Africa into 17 different virus sub-groups. (deepdyve.com)
  • The data therefore indicated a potential role for the bushpig in virus transmission in South-western Kenya, but there was no evidence of a direct sylvatic virus transmission cycle in Central Kenya. (cgiar.org)
  • Twenty O. porcinus-, 12 domestic pig- and three warthogderived viruses were genotyped at four polymorphic loci. (cgiar.org)
  • The purpose of this study is to determine whether immune globulin can limit the amount of yellow fever vaccine virus present in the blood after vaccination without compromising the immunit. (bioportfolio.com)
  • A major roadblock has been the lack of convenient genetic tools to study this pathogen, with periods of up to a year of labor intensive effort just to generate one or two modified viruses, let alone to generate attenuated vaccine candidates. (jcvi.org)
  • To date, a vaccine or treatment for the virus has yet to be developed although research is underway. (kticradio.com)
  • African swine fever is regarded as more lethal than conventional swine fever, also known as hog cholera, and there is no effective vaccine to protect swine from the deadly pig disease. (japannews.top)
  • Recombinant viruses containing both the lacI gene encoding the lac repressor and a strong virus late promoter modified by the insertion of one or two copies of the lac operator sequence at various positions were constructed. (asm.org)
  • Recombinant viruses can be selected by following the expression of either the Escherichia coli lacZ gene, which encodes β-galactosidase (β-Gal) ( 45 ), or the E. coli gusA gene, which encodes β-glucuronidase (GUS) ( 28 ). (asm.org)
  • The continuing spread of African swine fever (ASF) outside Africa in Europe, the Russian Federation, China and most recently to Mongolia and Vietnam, has heightened awareness of the threat posed by th. (bioportfolio.com)
  • Now, that work may help to fend off the threat from the African Swine Fever virus. (farms.com)
  • The virus is transmitted by ticks and direct contact between animals, and can also travel via contaminated food, animal feed and people moving from one place to another. (reuters.com)
  • Keeping a heightened level of biosecurity presence, which will help prevent African Swine Fever and other viruses or pathogens, will be beneficial. (farms.com)
  • These two processes have been recently linked together in the early cell defense mechanism against external pathogens, including viruses. (uam.es)
  • However, the virus is spreading due to changing production practices and increasing globalization. (kticradio.com)
  • This knowledge will help to identify strategies to keep it out of the country and assist in creating rapid and accurate virus identification techniques in case the virus does reach the U.S. (kticradio.com)
  • The use of COS-1 cells for studies of field and laboratory African swine fever virus samples. (semanticscholar.org)
  • If scientists understand how the disease spreads, they will be better able to control, or even stop, the spread of this virus. (kticradio.com)
  • Dengue virus is an arbovirus transmitted by mosquitoes which causes significant morbidity and mortality among children in tropical regions, especially in resource limited countries. (bioportfolio.com)
  • African swine fever: an unprecedented disaster and challenge to China. (bioportfolio.com)
  • As African swine fever (ASF) rages in China, neighboring countries such as Japan, South Korea and Taiwan, which have not yet been affected by the disease, are on high alert and doing everything in their power to prevent its spread. (flutrackers.com)
  • Highly contagious African swine fever virus has been detected in the luggage of a traveler from China at a Hokkaido airport, Japan's farm ministry said Monday. (japannews.top)
  • China is a major pig producer and accounts for about half the global population of swine, according to FAO. (japannews.top)
  • This project will help to design incentives and other actions that will reduce the risks and impact of ASF, benefiting smallholder farmers in more than 20 countries in eastern, central, western and southern Africa. (ilri.org)
  • Farmers are focused on ways to prevent the virus from entering the U.S. as losses would be staggering not only for the pork industry, but for other agriculture commodities as well. (kticradio.com)
  • K-State researchers currently are studying the African Swine Fever virus in collaboration with Megan Niederwerder, Steve Dritz, and Bob Rowland at the university's Biosecurity Research Institute, a bio-safety level 3 facility. (farms.com)
  • An analysis of African swine fever virus replicating DNA showed head-to-head and tail-to-tail linked molecules that may be replicative intermediates. (nih.gov)