Rational therapy of chronic venous insufficiency--chances and limits of the therapeutic use of horse-chestnut seeds extract. (1/23)BACKGROUND AND METHODS: We report two clinical studies, one already published, performed in patients with early and advanced chronic venous insufficiency (CVI). In both, compression therapy and oral therapy with horse-chestnut seeds extracts (HCSE) were compared to placebo. RESULTS: The published study in early CVI (Grade I) showed HCSE and compression to be superior to placebo and to be equivalent to each other in reducing lower leg volume, a measure for oedema. In the study, in advanced CVI (Grade II and IIIa), compression appeared to be superior to placebo, whereas HCSE was not. HCSE fared better in Grade II than in Grade IIIa patients. These results are discussed in the light of data from an in vitro model, where HCSE has been able to close the intercellular gaps in the venular endothelium. Not fully specified factors lead to an opening of these gaps, resulting in oedema as well as in local coagulation and thrombosis. The subsequent inflammation keeps these gaps open and initiates and maintains a chronic disease process, which may be the starting point of CVI. CONCLUSION: Due to its ability to close the venular endothelial gaps, HCSE seems to be a suitable and protecting therapy during the early stages of CVI. In later more severe stages compression therapy is indicated. Taking into account the observed negative impact of compression on quality of life, pharmacological CVI therapy should start early to avoid progress and to spare patients compression therapy. (+info)
Effects of sodium beta-aescin on expression of adhesion molecules and migration of neutrophils after middle cerebral artery occlusion in rats. (2/23)AIM: To investigate the effects of sodium beta-aescin on neutrophil migration and expression of adhesion molecules (ICAM-1 and E-selectin) after middle cerebral artery occlusion (MCAO) in rats. METHODS: Rats were pretreated with sodium beta-aescin for 7 d and then subjected to cerebral ischemia/reperfusion (I/R) injury induced by an MCAO. After a 2-h ischemia and a 24-h reperfusion, the infarct volume and neurological deficit were determined by the method of TTC staining and the Longa's score. The effect of sodium beta-aescin on the migration of neutrophils was evaluated by measuring the activity of myeloperoxidase (MPO) enzyme. The expressions of adhesion molecules were determined by immunohistochemistry and Western blot. RESULTS: Sodium beta-aescin significantly reduced the cerebral infarct volume and ameliorated the neurological deficit (P<0.05 or P<0.01). The MPO activity and the expressions of ICAM-1 and E-selectin in the vehicle-treated rats were increased significantly (P<0.01) after cerebral I/R. After treatment with sodium beta-aescin, the enzymatic activity of MPO and the expressions of these adhesion molecules were significantly reduced compared with the vehicle-treated group (P<0.05 or P<0.01). CONCLUSION: Sodium beta-aescin can attenuate brain injury, down-regulate the protein expressions of ICAM-1 and E-selectin, and reduce the migration of neutrophils after cerebral I/R. (+info)
Antiinflammatory triterpenoid saponins from the seeds of Aesculus chinensis. (3/23)Phytochemical study of the ethanol extract of the seeds of Aesculus chinensis led to the isolation of a new triterpenoid saponin (6), together with five known triterpenoid saponins (1-5). The structure of the new compound was elucidated on the basis of spectral data to be 21,28-di-O-acetylprotoaescigenin-3-O-[beta-D-glucopyranosyl(1-2)][beta-D-glucopyr anosyl(1-4)]-beta-D-glucopyranosiduronic acid (aesculiside A, 6). The antiinflammatory activities of the four main saponins (1-4) were compared with those of total saponin extracts, and single saponins showed more potent activity than total saponin extracts in mice. (+info)
Antioxidative and antigenotoxic effects of Japanese horse chestnut (Aesculus turbinata) seeds. (4/23)Japanese horse chestnut seed extract (HCSE) dose-dependently inhibited the autooxidation of linoleic acid (IC(50): 0.2 mg/ml), and the inhibition was almost complete at a concentration of 1 mg/ml. The HCSE scavenged DPPH (1,1-diphenyl-2-picrylhydrazyl) radicals and superoxide anions with EC(50)s of 0.65 and 0.21 mg/ml, respectively. However, it had no effect on hydrogen peroxide. The HCSE inhibited the genotoxicities of furylfuramide, N-methyl-N-nitrosourea, methyl methanesulfonate, mitomycin C, 2-aminoanthracene and aflatoxin B1 at a concentration of 1 mg/ml or more. Total polyphenol content of the HCSE was 21 mg/g (13 mg/g-seeds). These results indicate that the Japanese horse chestnut seed is an antioxidative and antimutagenic botanical resource. (+info)
Two new triterpenoid glycosides isolated from Aesculus assamica GRIFF. (5/23)Phytochemical study of the ethanol extract of the seeds of Aesculus assamica led to the isolation of two new triterpenoid saponins. The structure of the new compounds were elucidated on the basis of spectral data to be 28-O-acetyl-21-O-(4-O-angeloyl)-6-deoxy-beta-glucopyranosyl-3-O-[beta-glucopyrano syl(1-2)-O-[beta-glucopyranosyl(1-4)]-beta-glucuronopyranosyl]protoaescigenin (1), and 21-O-(4-O-angeloyl)-6-deoxy-beta-glucopyranosyl-3-O-[beta-glucopyranosyl(1-2)-O-[ beta-glucopyranosyl(1-4)]-beta-glucuronopyranosyl]protoaescigenin (2). Their in vitro bioactivity against plant pathogenic fungus Pyricularia oryzae and cytotoxicity against K562 and HCT-15 cell lines were evaluated. (+info)
Using horsechestnut seed extract in the treatment of venous leg ulcers: a cost-benefit analysis. (6/23)Venous leg ulcers affect approximately 0.6% of the western population, consuming millions of healthcare dollars every year. To determine whether an alternative venous ulcer treatment using horsechestnut seed extract-- Aesculus hippocastanum-- and conventional therapy involving dressings and compression was more cost-effective than using conventional therapy alone, a 12-week cost-benefit analysis of horsechestnut seed extract therapy was conducted. The study, using data from a 12-week prospective, randomized, placebo-controlled trial conducted in South Australia in 2002-2004, involved 54 patients with venous ulceration who received treatment through a large South Australian district nursing service. Taking into account the cost of horsechestnut seed extract, dressing materials, travel, staff salaries, and infrastructure for each patient, horsechestnut seed extract therapy combined with conventional therapy was found to be more cost-effective than conventional therapy alone with an average savings of AUD 95 in organizational costs and AUD 10 in dressing materials per patient. This study confirms that dressing change frequency has a significant impact on the total cost of wound care and suggests that district nursing service operation efficiency may be enhanced through the use of horsechestnut seed extract as a result of less frequent nursing visits. Further study of this treatment modality is warranted. (+info)
Horse chestnut extract induces contraction force generation in fibroblasts through activation of Rho/Rho kinase. (7/23)Contraction forces generated by non-muscle cells such as fibroblasts play important roles in determining cell morphology, vasoconstriction, and/or wound healing. However, few factors that induce cell contraction forces are known, such as lysophosphatidic acid and thrombin. Our study analyzed various plant extracts for ingredients that induce generation of cell contraction forces in fibroblasts populating collagen gels. We found that an extract of Horse chestnut (Aesculus hippocastanum) is able to induce such contraction forces in fibroblasts. The involvement of actin polymerization and stress fiber formation in the force generation was suggested by inhibition of this effect by cytochalasin D and by Rhodamine phalloidin. Rho kinase inhibitors (Y27632 and HA1077) and a Rho inhibitor (exoenzyme C3) significantly inhibited the force generation induced by the Horse chestnut extract. H7, which inhibits Rho kinase as well as other protein kinases, also significantly inhibited induction of force generation. However, inhibitors of other protein kinases such as myosin light chain kinase (ML-9), protein kinase C (Calphostin), protein kinase A (KT5720), and tyrosine kinase (Genistein, Herbimycin A) had no effect on force generation induced by Horse chestnut extract. These results suggest that the Horse chestnut extract induces generation of contraction forces in fibroblasts through stress fiber formation followed by activation of Rho protein and Rho kinase but not myosin light chain kinase or other protein kinases. (+info)
Antiinflammatory effect of Japanese horse chestnut (Aesculus turbinata) seeds. (8/23)The antiinflammatory effects of Japanese horse chestnut (Aesculus turbinata) seeds were examined in vivo and in vitro. The extract of this seed (HCSE) inhibited croton oil-induced swelling of the mouse concha. HCSE inhibited cyclooxygenase (COX) -1 and -2 activities, but had no effect on 15-lipoxygenase and phospholipase A2 activities. Inhibition of COX-2 occurred at a lower concentration of HCSE than for COX-1. Japanese horse chestnut seeds contain coumarins and saponins, but these chemicals did not inhibit COX activities. These results suggest that the antiinflammatory effect of Japanese horse chestnut seeds is caused, at least partly, by the inhibition of COX. The inhibitor of COX in this seed may be a chemical(s) other than coumarins and saponins. (+info)
... exhibits a classical Arcto-Tertiary distribution. Mexican buckeye seedpods resemble the Aesculus seedpods, but belong ... The species of Aesculus include: The most familiar member of the genus worldwide is the common horse chestnut, Aesculus ... 2016 Wikimedia Commons has media related to Aesculus. Germplasm Resources Information Network: Aesculus Forest, F., Drouin, J. ... The yellow buckeye, Aesculus flava (syn. A. octandra), is also a valuable ornamental tree with yellow flowers, but is less ...
Tropicos Aesculus turbinata Plant list Aesculus turbinata Blume, Rumphia. 3: 195. 1847. Harlan, Jack R. (1995). The Living ... Aesculus turbinata, common name Japanese horse-chestnut (Tochinoki or Tochi (トチノキ（栃の木） or トチ（栃、橡）)), is native to Japan but ... Today the seeds are used in Japanese cuisine to prepare "Tochimochi". Aesculus was named by Linnaeus, and the name is derived ... Aesculus, Endemic flora of Japan, Trees of Japan). ... from the Roman name, aesculus, of the durmast oak. Turbinata ...
ISBN 0-394-50760-6. photo of Yellow Red Buckeye Aesculus pavia images at bioimages.vanderbilt.edu Aesculus pavia at Wikipedia's ... There are two varieties: Aesculus pavia var. pavia: typical red buckeye. Aesculus pavia var. flavescens: yellow-flowered red ... Red buckeye has hybridized with common horse-chestnut (Aesculus hippocastanum) in cultivation, the hybrid being named Aesculus ... Aesculus pavia, known as red buckeye or firecracker plant (formerly Pavia rubra), is a species of deciduous flowering plant. ...
Wott, John A. "The Many Faces of Aesculus" (PDF). Washington Park Arboretum Bulletin. "Aesculus hippocastanum". Euro+Med ... the term buckeye is more commonly used for New World members of the genus Aesculus. Aesculus hippocastanum is native to a small ... In the US state of Ohio, the seeds of the related Aesculus glabra are called 'buckeyes' and give rise to one of the state's ... Aesculus hippocastanum is affected by the leaf-mining moth Cameraria ohridella, whose larvae feed on horse chestnut leaves. The ...
"Gammarotettix aesculus Report". Integrated Taxonomic Information System. Retrieved 2019-09-23. "Gammarotettix aesculus". GBIF. ... Gammarotettix aesculus is a species of camel cricket in the family Rhaphidophoridae. It is found in North America. " ...
... , the painted buckeye, is a species of shrub. The species has five leaflets that are 4.5 to 6 inches (11 to ... BGCI) (2020). "Aesculus sylvatica". IUCN Red List of Threatened Species. 2020: e.T152909108A152909110. doi:10.2305/IUCN.UK.2020 ... ISBN 0-307-13658-2. "Poisonous Plants: Aesculus sylvatica". Poisonous Plants of North Carolina. Archived from the original on ... Wikimedia Commons has media related to Aesculus sylvatica. IUCN SSC Global Tree Specialist Group.; Botanic Gardens Conservation ...
"Aesculus parryi A.Gray". www.gbif.org. "Aesculus parryi A.Gray - The Plant List". www.theplantlist.org. "Aesculus parryi A.Gray ... "SEINet Portal Network - Aesculus parryi". swbiodiversity.org. Wiggins, Ira L. (1932). "The Lower California Buckeye, Aesculus ... Aesculus parryi, known as the Parry buckeye or Baja California buckeye, is a species of shrub or small tree in the genus ... v t e (Articles with short description, Short description matches Wikidata, Articles with 'species' microformats, Aesculus, ...
Aesculus × carnea
... , or red horse-chestnut, is a medium-sized tree, an artificial hybrid between A. pavia (red buckeye) and A. ... Aesculus × carnea's features are typically intermediate between the parent species, but it inherits the red flower color from A ... ISBN 978-0-618-06889-0. Media related to Aesculus × carnea at Wikimedia Commons v t e (All articles with dead external links, ... "Aesculus × carnea 'Briotii'". Royal Horticultural Society. Retrieved 25 July 2013.[permanent dead link] Govaerts, R., ...
"RHS Plantfinder - Aesculus indica 'Sydney Pearce'". Retrieved 4 January 2018. Media related to Aesculus indica at Wikimedia ... Aesculus indica is an attractive tree growing to 9-12 m (30-40 ft) with a spread of about 11-15 m (35-50 ft). It is hardy to − ... Aesculus indica, commonly known as the Indian horse-chestnut or Himalayan horse chestnut, is a species of deciduous broad- ... "Aesculus indica (Wall. ex Cambess.) Hook. , Plants of the World Online , Kew Science". Plants of the World Online. Retrieved ...
... Interactive Distribution Map of Aesculus californica Aesculus californica - U.C. Photo gallery (Articles ... ISBN 0-520-04948-9. Jepson Flora Project: Aesculus californica USDA Plants Profile for Aesculus californica (California buckeye ... Aesculus' is Linnaeus' name for horse chestnuts. It is derived from the old Roman name for a different species, Quercus petraea ... Aesculus californica, commonly known as the California buckeye or California horse-chestnut, is a species of buckeye native to ...
Wikimedia Commons has media related to Aesculus wangii. Rushforth, K. (1998). "Aesculus wangii". IUCN Red List of Threatened ... Aesculus wangii is a species of tree in the family Sapindaceae, found in southern China (Yunnan) and northern Vietnam. It is ... "Aesculus assamica Griffith, Not. Pl. Asiat. 4: 540. 1854". Flora of China. Retrieved 23 May 2018. v t e (Articles with short ... "Aesculus wangii Hu". World Checklist of Selected Plant Families. Royal Botanic Gardens, Kew. Retrieved 23 May 2018 - via The ...
... , the Chinese horse chestnut (Chinese:七叶树 qi ye shu), is a tree species in the genus Aesculus found in ... Data related to Aesculus chinensis at Wikispecies Media related to Aesculus chinensis at Wikimedia Commons v t e (Articles with ... Aesculus, Plants described in 1833, Taxa named by Alexander von Bunge, All stub articles, Sapindales stubs). ... "Antiviral Flavonoids from the Seeds of Aesculus chinensis". Journal of Natural Products. 67 (4): 650-3. doi:10.1021/np030470h. ...
"Aesculus parviflora". Royal Horticultural Society. Retrieved 10 March 2020. Wikimedia Commons has media related to Aesculus ... "Aesculus parviflora". NatureServe Explorer. NatureServe. Retrieved 2019-01-22. USDA, NRCS (n.d.). "Aesculus parviflora". The ... Aesculus parviflora grows to 2-4 m tall. The leaves are arranged in opposite pairs, palmately compound with 5-7 leaflets, each ... Aesculus parviflora, the bottlebrush buckeye, is a species of suckering deciduous shrub in the family Sapindaceae. The species ...
Missouri Botanical Garden horticultural treatment: Aesculus flava . accessed 1.31.2013 "RHS Plant Selector - Aesculus flava". ... Aesculus flava, the yellow buckeye, common buckeye, or sweet buckeye, is a species of deciduous tree. It is native to the Ohio ... Aesculus flava is cultivated as an ornamental tree. The tree's showy yellow flowers and good autumn color are attractive in ... 12-U*1 Bioimages.vanderbilt.edu - Aesculus flava photo gallery Ohio Buckeye Trivia Cards tell about the buckeye, buckeye tree, ...
... Missouri Botanical Garden "Aesculus glabra". County-level distribution map from the North American Plant Atlas ... Wikimedia Commons has media related to Aesculus glabra. National Register of Big Trees Aesculus glabra images at bioimages. ... Aesculus glabra, commonly known as Ohio buckeye, is a species of tree in the soapberry family (Sapindaceae) native to North ... Foliage and fruit Inflorescence Dried buckeye nuts Closeup of trunk Aesculus glabra has little use as a timber tree due to its ...
Aesculus (Carnea Group) 'Pendula'
... , or Weeping Red Horse Chestnut, was a weeping tree and a cultivar of the Aesculus Carnea ... Aesculus × carnea var. pendulum A.Henry (1907) Govaerts, R., Michielsen, K. & Jablonski, E. (2011). Untraced Weeping Broadleaf ... v t e (Webarchive template wayback links, Articles with 'species' microformats, Aesculus, Weeping trees, Extinct cultivars, All ... Group, the Red Horse Chestnut Group, which is a cultivar group of artificial hybrids between Aesculus pavia and A. ...
... is a species of lace bug Tingidae native to North America. C. aesculi's host plant is the yellow buckeye, ( ... "The Biology of Corythucha aesculi O. & D. (Hemiptera, Tingitidae) on the yellow buckeye, Aesculus octandra Marsh" (PDF). Paper ... Aesculus octandra) Marsh and the insect can attain very high densities. C. aesculi is preyed upon by a wide variety of other ...
... is a species of thrips in the family Heterothripidae. It is found in North America. "Heterothrips aesculi ... "Heterothrips aesculi". GBIF. Retrieved 2019-09-24. "Heterothrips aesculi species Information". BugGuide.net. Retrieved 2019-09- ...
ISBN 0-930588-62-2. Hogan, C. Michael (2008). Stromberg, N. (ed.). Aesculus californica. Globaltwitcher.com. Kroeber, A. L. ( ...
Clarence House Chase
Aesculus Press. 1990. p. 49. ISBN 1-871093-21-X. Race Recordings 1989-2004  (Articles with short description, Short ...
Aesculus Press. 1990. p. 53. ISBN 1-871093-21-X. Race Recordings  (Articles with short description, Short description ...
Coral Gold Cup
Aesculus Press. 1990. p. 42. ISBN 1-871093-21-X. The Breedon Book of Horse Racing Records. Breedon Books. 1993. p. 225. ISBN 1- ...
Aesculus Press. ISBN 9781904328087. Retrieved 2012-03-08. "Mystiko Stud Record". Racing Post. 2012-02-15. Retrieved 2012-03-08 ...
1988 Epsom Derby
Aesculus Press. 1988. p. 59. ISBN 0-9509338-8-0. "Stammtafeln". Galopp Sieger. Galopp Sieger. Retrieved 20 April 2020. " ...
Reynoldstown Novices' Chase
Aesculus Press. 1990. p. 52. ISBN 1-871093-21-X. Race Recordings 1980-2005  (Articles with short description, Short ...
1987 Epsom Derby
Aesculus Press. 1988. p. 59. ISBN 0-9509338-8-0. "Stammtafeln". Galopp Sieger. Galopp Sieger. Retrieved 20 April 2020. " ...
County Handicap Hurdle
Aesculus Press. 1990. p. 64. ISBN 1-871093-21-X. (CS1: Julian-Gregorian uncertainty, Pages containing links to subscription- ...
Aesculus Press. 1990. p. 40. ISBN 1-871093-21-X. Race Recordings (Articles with short description, Short description matches ...
Hogan, C. Michael (2008). Stromberg, N. (ed.). "Aesculus californica". Globaltwitcher.com. Archived from the original on 22 ...
Aesculus Press. 1992. p. 60. ISBN 1-871093-91-0. Race Recordings  (Articles with short description, Short description ...
Hamamelis Aesculus Pellets
AESCULUS GLABRA NUT (UNII: IHY79HC33C) (AESCULUS GLABRA NUT - UNII:IHY79HC33C) AESCULUS GLABRA NUT. 3 [hp_X]. ... HAMAMELIS AESCULUS- hamamelis aesculus pellet Uriel Pharmacy Inc. Disclaimer: This homeopathic product has not been evaluated ... Active Ingredients: Aesculus (Horse chestnut) 3X, Hamamelis (Witch hazel) 3X, Paeonia (Peony) 3X, Pulsatilla (Pasqueflower) 3X ...
Aesculus - PubChem Substance - NCBI
MedlinePlus - Search Results for: ACTIVATED CHARCOAL OR AESCULUS HIPPOCASTANUM FLOWER OR "ANTI-INTERLEUKIN-1.ALPHA."...
Dietary Supplements in Patients With Cancer: Risks and Key Concepts, Part 1
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Quantification of Toxins in Soapberry (Sapindaceae) Arils: Hypoglycin A and Methylenecyclopropylglycine - PubMed
TREE NUMBER DESCRIPTOR
Phytomedicine research in Germany. | Environmental Health Perspectives | Vol. 107, No. 10
DeCS 2019 - Deleted terms
Aesculus hippocastanum Narrower Concept UI. M0397120. Registry Number. txid43364. Terms. Aesculus hippocastanum Preferred Term ... Aesculus Preferred Term Term UI T459821. Date08/31/2001. LexicalTag NON. ThesaurusID NLM (2003). ... Aesculus Preferred Concept UI. M0397119. Registry Number. txid43363. Related Numbers. txid43364. Scope Note. A plant genus of ... Aesculus. Tree Number(s). B01.875.800.575.912.250.503.500. B01.875.800.575.912.250.885.278.500. Unique ID. D031319. RDF Unique ...
Aesculus hippocastanum Narrower Concept UI. M0397120. Registry Number. txid43364. Terms. Aesculus hippocastanum Preferred Term ... Aesculus Preferred Term Term UI T459821. Date08/31/2001. LexicalTag NON. ThesaurusID NLM (2003). ... Aesculus Preferred Concept UI. M0397119. Registry Number. txid43363. Related Numbers. txid43364. Scope Note. A plant genus of ... Aesculus hippocastanum Buckeyes Common Horse Chestnut Horse Chestnuts Red Chestnut Registry Number. txid43363. Related Numbers ...
Code System Concept
DeCS 2019 - Deleted terms
Issue Dates: September 1942 - FDA Notices of Judgment Collection, 1908-1966 Search Results
Adjudicating Courts: Western District of Missouri - FDA Notices of Judgment Collection, 1908-1966 Search Results
Pesquisa | Portal Regional da BVS
Division of AIDS Anti-HIV/OI/TB Therapeutics Database - Surveillance Memo
MESH TREE NUMBER CHANGES - 2011 MeSH. August 17, 2010
DailyMed - BIOWHITE RESILIENT MASSAGE- dimethicone cream
- Aesculus hippocastanum (Horse chestnut). (nih.gov)
- Steroidal constituents and anti-inflammatory activity of the horse chestnut (Aesculus hippocastanum L.) bark. (nih.gov)
- Search: activated charcoal OR aesculus hippocastanum flower OR anti-interleukin-1.alpha. (nih.gov)
- 1): The structures, inhibitory effects on ethanol absorption, and hypoglycemic activity of escins la, lb, lla, llb, and llla from the seeds of Aesculus hippocastanum L. Chem. (naturopedia.com)
- aesculi on Aesculus hippocastanum. (bvsalud.org)
- Aesculus Glabra is available in all the potencies, formats and brands specified below. (abchomeopathy.com)
- For uses of Aesculus Glabra see the main Aesculus Glabra page for materia medica from Boericke, Clarke, T.F. Allen and our reversed & reworded Kent repertory. (abchomeopathy.com)
- Aesculus Glabra is not available from Boiron. (abchomeopathy.com)
- Aesculus glabra, aka Stinking Buckeye or Fetid Buckeye, is native to Ohio, and not surprisingly, our most common Buckeye. (simplyliving.org)
- 19. Cytotoxic triterpenoid saponins from Aesculus glabra Willd. (nih.gov)
- Aesculus x carnea or Red horse chestnut pale pink form. (mossvalepark.com)
- The two Ohio natives, Ohio Buckeye and Yellow Buckeye, Aesculus flava, have similar leaves, but Ohio Buckeye leaves emit a foul odor when crushed. (simplyliving.org)
- Many of the others are referred to as Horse Chestnuts, but they are also Buckeyes and belong to the same genus, Aesculus. (simplyliving.org)
- Below are the main rubriks (i.e strongest indications or symptoms) of Aesculus in traditional homeopathic usage , not approved by the FDA. (abchomeopathy.com)
- Aesculus pavia are an important source of nectar for butterflies and hummingbirds when food is scarce, and attracts the Ruby-throated Hummingbird in particular. (servescape.com)
- Toxicity of seeds of three Aesculus spp to chicks and hamsters. (naturopedia.com)