Advanced Oxidation Protein Products: A class of dityrosine-containing protein-derived molecules formed by OXIDATIVE STRESS. Their accumulation in plasma is associated with certain pathological conditions.Oxidative Stress: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).Glycosylation End Products, Advanced: Products derived from the nonenzymatic reaction of GLUCOSE and PROTEINS in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of DIABETES MELLITUS.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).Malondialdehyde: The dialdehyde of malonic acid.Serum Albumin: A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.Blood Proteins: Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.Biological Markers: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.Antioxidants: Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.Protein Carbonylation: The appearance of carbonyl groups (such as aldehyde or ketone groups) in PROTEINS as the result of several oxidative modification reactions. It is a standard marker for OXIDATIVE STRESS. Carbonylated proteins tend to be more hydrophobic and resistant to proteolysis.
(1/20) The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients.

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(2/20) Advanced oxidation protein products as prognostic biomarkers for recovery from acute kidney injury after coronary artery bypass grafting.

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(3/20) Decreased oxidant profile and increased antioxidant capacity in naturally postmenopausal women.

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(4/20) Advanced oxidation protein products activate intrarenal renin-angiotensin system via a CD36-mediated, redox-dependent pathway.

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(5/20) In search of malignant transformation: a pilot study.

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(6/20) Role of reactive oxygen species in the renal fibrosis.

Renal fibrosis is a common pathway of progressive renal diseases leading to end-stage renal disease regardless of the etiology. Accumulating evidence indicates that oxidative stress, resulting in generation of reactive oxygen species (ROS), plays a critical role in the initiation and progression of fibrotic diseases. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is the predominant enzyme source for ROS generation and is now recognized as a key mediator of cell proliferation and matrix accumulation in renal disease. Multiple stimuli and agonists, such as transforming growth factor beta1, tumor necrosis factor, platelet derived growth factor, angiotensin II, hyperglycemia, oxidized low-density lipoprotein and albumin have been shown to alter the activity or expression of the NADPH oxidase and ultimately increase ROS production. ROS directly incites damage to biologically important macromolecules and leads to generation of the so-called advanced oxidation protein products (AOPPs) and advanced glycation end products, which are not only markers of oxidative stress but also cause renal injury. Targeting NADPH oxidase and/or reducing AOPPs production might be a novel strategy for the therapeutic intervention of variety of fibrotic kidney disorders.  (+info)

(7/20) Sorafenib-induced hepatocellular carcinoma cell death depends on reactive oxygen species production in vitro and in vivo.

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(8/20) Antioxidant effects of potassium ascorbate with ribose therapy in a case with Prader Willi Syndrome.

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*  Parathyroid hormone
"Infection and Immunity Immunophenotyping (3i) Consortium". Drüeke TB, Massy ZA (2003). "Advanced oxidation protein products, ... PTH was one of the first hormones to be shown to use the G-protein, adenylyl cyclase second messenger system. PTH reduces the ... PTH is secreted when [Ca2+] is decreased (Calcitonin is secreted when serum calcium levels are elevated). The G-protein coupled ... In the parathyroid gland, high concentrations of extracellular calcium result in activation of the Gq G-protein coupled cascade ...
*  Advanced glycation end-product
Fuentealba D, Friguet B, Silva E. Advanced glycation endproducts induce photocrosslinking and oxidation of bovine lens proteins ... Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars. They can ... Nevertheless, the resistance of extracellular matrix proteins to proteolysis renders their advanced glycation end products less ... Advanced glycation end products induce in vitro cross-linking of alpha-synuclein and accelerate the process of intracellular ...
*  Prodigiosin
Ring A fragment is transferred from the peptidyl carrier protein (PCP) to the Acyl Carrier Protein (ACP) by a KS domain, ... Oxidation of the resulting ring yields the final pyrrole ring C. Finally, these two pieces are stitched together in a ... Advances in Applied Microbiology. 47: 1-32. doi:10.1016/S0065-2164(00)47000-0. ISBN 9780120026470. PMID 12876793. Williamson NR ... This completes the convergent synthesis of the natural product. Project SHAD Bennett JW, Bentley R (2000). "Seeing red: The ...
*  Metagenics
Recent advances have allowed the chains to be synthesized together by inserting the human proinsulin gene into E. coli cells, ... The limiting factor for the use of microorganisms like E. coli in biosynthesis of gene products like insulin is time, yet due ... Joining of the two chains was often carried out through air oxidation with low efficiency. A 1978 study by Goedell et al. ... protein, or other biochemicals from simpler starting materials. The genetic engineering of E. coli with the specific task of ...
*  Glucose oxidase
GOx is a dimeric protein, the 3D structure of which has been elucidated. The active site where glucose binds is in a deep ... The glucose oxidase enzyme (GOx) also known as notatin (EC number 1.1.3.4) is an oxido-reductase that catalyses the oxidation ... RSC Advances. 5: 13570-8. doi:10.1039/C4RA16852F. "Detlev Müller discovers glucose oxidase". Tacomed.com. Retrieved 13 June ... and to control glucose in vegetal raw material and food products.[citation needed] In the glucose oxidase assay, the glucose is ...
*  Aureusidin synthase
This product then undergoes an oxidative cyclization and then an isomerization to give the final product, but it is possible ... 2. The first step in the process results in a hydroxylation in the 3 position (for THC) and an oxidation to a diketone ring. ... It is unclear whether this aurone formation is due to an alternative mechanism or another protein. Aureusidin is a plant ... doi:10.1016/S0958-1669(99)80035-4. Haudecoeur, R; Boumendjel, A (2012). "Recent advances in the medicinal chemistry of aurones ...
*  AOC3
This rise in metabolic products contributes to generating advanced glycation end-products and oxidative stress along with the ... As for stroke patients, the products from deamination induce cytotoxicity protein cross-linking and amyloid-beta (Aβ) ... Amine oxidases are a family of enzymes that catalyze the oxidation of various endogenous amines, including histamine or ... Additionally, hydrogen peroxide, along with aldehydes and glucose, is involved in generating advanced glycation end-products ...
*  Methanogenesis
The useful products of methanogenesis are absorbed by the gut, but methane is released from the animal mainly by belching ( ... During advanced stages of organic decay, all electron acceptors become depleted except carbon dioxide. Carbon dioxide is a ... These organisms may accomplish reverse methanogenesis using a nickel-containing protein similar to methyl-coenzyme M reductase ... Aerobic methane production Anaerobic digestion Anaerobic oxidation of methane Electromethanogenesis Hydrogen cycle Methanotroph ...
*  Performic acid
"Performic Acid Oxidation of Proteins". Cold Spring Harbor Protocols. 2007: pdb.prot4698. doi:10.1101/pdb.prot4698. Gehr, R; ... Using an excess of either reactant shifts the equilibrium towards the product side. The aqueous product solution can be ... Chen, D; Moreau, M (2009). "Performic acid (PFA): tests on an advanced primary effluent show promising disinfection performance ... The popularity of performic acid as a sterilizer originates from the safe nature of its degradation products, mostly carbon ...
*  Radical (chemistry)
... amino acid oxidation products (meta-tyrosine, ortho-tyrosine, hydroxy-Leu, dityrosine etc.), peptide oxidation products ( ... It is gaining prominence as a model oxidant in small molecule and protein therapeutics for its ability to initiate oxidation ... Recent advances in radical polymerization methods, known as living radical polymerization, include: Reversible addition- ... Radicals may also be formed by single-electron oxidation or reduction of an atom or molecule: an example is the production of ...
*  Bleach
... which is activated for nucleophilic oxidation. Peracetic acid and ozone are used in the manufacture of paper products, ... Bleach, particularly sodium hypochlorite, has been shown to react with a microbe's heat shock proteins, stimulating their role ... Cotton, F.A; G. Wilkinson (1972). Advanced Inorganic Chemistry. John Wiley and Sons Inc. ISBN 0-471-17560-9. Occupational ... "How Products Are Made Volume 2". May 2011. "Sodium Hypochlorite Chemical Production". by Intratec, ISBN 978-0615702179. Vogt, H ...
*  Metascreen
... is an advanced non-invasive metabolic screening test distributed by Cordlife Group Limited ("Cordlife"). It can ... the waste product from the kidney) particularly useful for medical diagnostics. The key advantages of using urine as a biofluid ... it being largely free from interfering proteins or lipids. Although the human urine metabolome is a subset of the human serum ... such as sugar metabolism disorders and fatty acid oxidation disorders. Indeed, GC-MS analysis is increasingly becoming a common ...
*  Human serum albumin
Albumin thiol oxidation and serum protein carbonyl formation are progressively enhanced with advancing stages of chronic kidney ... Fu BL, Guo ZJ, Tian JW, Liu ZQ, Cao W (2009). "[Advanced glycation end products induce expression of PAI-1 in cultured human ... Moreover, the glycation can result in the formation of Advanced Glycation End-Products (AGE), which result in abnormal ... It is the most abundant protein in human blood plasma; it constitutes about half of serum protein. It is produced in the liver ...
*  Agmatine
Matrix metalloproteases (MMPs). Indirect down-regulation of the enzymes MMP 2 and 9. Advanced glycation end product (AGE) ... Protein ADP-ribosylation. Inhibition of protein arginine ADP-ribosylation. ... An alternative pathway, mainly in peripheral tissues, is by diamine oxidase-catalyzed oxidation into agmatine-aldehyde, which ...
*  Buformin
The bioavailability of oral buformin and other biguanides is 40%-60%. Binding to plasma proteins is absent or very low. The ... United States National Library of Medicine ChemLDplus advanced database Enrique Ravina, Hugo Kubinyi. The Evolution of Drug ... Jacker, HJ (1964). "New Pharmacologic Products. 2. Buformin For Oral Therapy Of Diabetes". Pharm Prax. 10: 247-9. Eustace ... ability to disrupt the Warburg effect and revert the cytosolic glycolysis characteristic of cancer cells to normal oxidation of ...
*  Model lipid bilayer
... lipid membranes by oxidation products of cholesterol". Nature. 212 (5063): 718-719. Bibcode:1966Natur.212..718T. doi:10.1038/ ... reconstitue proteins and protein channels or made for use in studying electrophysiology. Detergent micelles are another class ... More advanced electrical characterization has been particularly important in the study of voltage gated ion channels. Membrane ... depending on the type of protein coat, between 10 and 20 nm). Membrane proteins incorporated into and solubilized by Nanodiscs ...
*  Flavobacterium psychrophilum
Most of the degradation products of host proteins and lipids by the F. psychrophilum are available as citric acid cycle ... Beta-oxidation of fatty acids is performed by a long-chain fatty acid-CoA ligase, three fatty acid dehydrogenases, a crotonase ... Journal of Advanced Research, 2(2), 97-108. Hesami, S., Metcalf, D. S., Lumsden, J. S., & MacInnes, J. I. (2011). ... which is predicted to contain 2,432 protein-coding genes. Compared to environmental members of the family, it has a small ...
*  Tobacco
Starch is converted to sugar, which glycates protein, and is oxidized into advanced glycation endproducts (AGEs), a ... Tobacco is a product prepared from the leaves of the tobacco plant by curing them. The plant is part of the genus Nicotiana and ... Curing and subsequent aging allow for the slow oxidation and degradation of carotenoids in tobacco leaf. This produces certain ... Cigarettes are a product consumed through inhalation of smoke and manufactured from cured and finely cut tobacco leaves and ...
*  Copper
Frieden, E.; Hsieh, H. S. (1976). "Ceruloplasmin: The copper transport protein with essential oxidase activity". Advances in ... Antimicrobial copper alloy products are now being installed in healthcare facilities in the U.K., Ireland, Japan, Korea, France ... Like oxide, fluoride is a highly basic anion and is known to stabilize metal ions in high oxidation states. Both copper(III) ... Several copper proteins, such as the "blue copper proteins", do not interact directly with substrates, hence they are not ...
*  Protein footprinting
... of total protein) at a number of amino acid side chains across the proteins. The rate or level of oxidation at the reactive ... Analysis of the products by mass spectrometry reveals that proteins to are oxidized in a limited manner (some 10-30% ... Maleknia, Simin D.; Downard, Kevin M. (2014). "Advances in radical probe mass spectrometry for protein footprinting in chemical ... These approaches have since been used to determine protein structures, protein folding, protein dynamics, and protein-protein ...
*  Tyrosine hydroxylase
Haavik J, Flatmark T (Oct 1987). "Isolation and characterization of tetrahydropterin oxidation products generated in the ... MAPKAPK2 (mitogen-activated-protein kinase-activating protein kinase) has a preference for Ser40, but also phosphorylates Ser19 ... Advances in Enzymology and Related Areas of Molecular Biology. Advances in Enzymology - and Related Areas of Molecular Biology ... Tyrosine hydroxylase is activated by phosphorylation dependent binding to 14-3-3 proteins. Since the 14-3-3 proteins also are ...
*  Dirigent protein
In the absence of dirigent protein, pinoresinol is a relatively minor product of lignan biosynthesis. When dirigent protein is ... dirigent protein does not itself appear to catalyze the oxidation of coniferyl alcohol to form radicals. The activity of ... Davin L.B.; Lewis N.G. (August 2005). "Dirigent phenoxy radical coupling: advances and challenges". Current Opinion in ... Dirigent proteins are members of a class of proteins which dictate the stereochemistry of a compound synthesized by other ...
*  CYP4F22
Advances in pharmacology (San Diego, Calif.). Advances in Pharmacology. 74: 223-62. doi:10.1016/bs.apha.2015.05.002. ISBN ... The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of ... see Omega oxidation). This hydroxylation may: a) produce a biologically important signaling molecule such as occurs in the ... 100-fold less potent product, 5-oxo-20-hydroxy-eicosatetraenoic acid, or c) be the first step in the further metabolism of ...
*  Circadian rhythm
... of co-evolution of redox proteins with circadian oscillators in all three domains of life following the Great Oxidation Event ... Their interactions result in an interlocked feedback loop of gene products resulting in periodic fluctuations that the cells of ... light can advance or delay the circadian rhythm. Both the PRC and the required illuminance vary from species to species and ... But their proteins levels remain low until dusk, because during daylight also activates the doubletime (dbt) gene. DBT protein ...
*  Epoxide hydrolase
Olefin oxidation using organic peroxides and metal catalysts)) diol products. They differ, however, in subcellular location, ... Furthermore, Asp104, His333, and Asp302 form the catalytic triad of the protein and is critical to function of the protein. At ... particularly in the tissues of more advanced or morphologically-based (i.e. Gleason score) more aggressive cancers; this ... The substrate(s) and physiological function of Peg1/MEST are not known; however, the protein may play a role in mammalian ...
*  Metabolism
This oxidation releases carbon dioxide as a waste product. In anaerobic conditions, glycolysis produces lactate, through the ... Proteins are made of amino acids arranged in a linear chain joined together by peptide bonds. Many proteins are enzymes that ... Advances in Microbial Physiology. 39: 235-89. doi:10.1016/S0065-2911(08)60018-1. ISBN 978-0-12-027739-1. PMID 9328649. Pace NR ... In prokaryotes, these proteins are found in the cell's inner membrane. These proteins use the energy released from passing ...
Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK/NF-κB...  Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK/NF-κB...
Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK/NF-κB- ... To determine whether advanced oxidation protein products (AOPPs) can induce the expression of chemokine monocyte ... Pretreatment with SLs inhibited MCP-1 mRNA and protein expression and suppressed IKKβ and NF-κB p65 phosphorylation and IκBα ... MCP-1 mRNA and protein expression were tested using quantitative real-time PCR and ELISA, respectively, and the protein levels ...
more infohttps://www.hindawi.com/journals/omcl/2015/934058/abs/
Antioxidant Supplementation in Renal Replacement Therapy Patients: Is There Evidence? : Table 1  Antioxidant Supplementation in Renal Replacement Therapy Patients: Is There Evidence? : Table 1
... advanced oxidation protein products; AGEs: advanced glycation end-products; 8-OHdG: 8-hydroxy deoxyguanosine; 8-oxodG: 8-oxo-2 ... Lipid oxidation. Free radicals. Protein oxidation. DNA oxidation. Antioxidants. TBARS. MDA. Ox-LDL. F2-isoprostanes. ...
more infohttps://www.hindawi.com/journals/omcl/2019/9109473/tab1/
Impact of angiotensin II receptor blocker on plasma levels of adiponectin and advanced oxidation protein products in peritoneal...  Impact of angiotensin II receptor blocker on plasma levels of adiponectin and advanced oxidation protein products in peritoneal...
Plasma levels of advanced oxidation protein products (AOPP) and adiponectin were measured before and 3 months after candesartan ... Impact of angiotensin II receptor blocker on plasma levels of adiponectin and advanced oxidation protein products in peritoneal ... Blood Proteins / analysis*. Female. Humans. Kidney Failure, Chronic / blood*, complications, therapy*. Male. Middle Aged. ... Oxidation-Reduction / drug effects. Oxidative Stress / drug effects*. Peritoneal Dialysis*. Tetrazoles / administration & ...
more infohttp://www.biomedsearch.com/nih/Impact-angiotensin-II-receptor-blocker/16940715.html
OXIDATIVE STRESS IN CHRONIC RENAL FAILURE AND HYPERTESION: ROLE OF ADVANCED OXIDATION PROTEIN PRODUCTS (AOPP) | IRIS Università...  OXIDATIVE STRESS IN CHRONIC RENAL FAILURE AND HYPERTESION: ROLE OF ADVANCED OXIDATION PROTEIN PRODUCTS (AOPP) | IRIS Università...
INTRODUCTION AND AIMS: Serum advanced oxidation protein products (AOPP) are new markers of protein damage induced by oxidative ... INTRODUCTION AND AIMS: Serum advanced oxidation protein products (AOPP) are new markers of protein damage induced by oxidative ... OXIDATIVE STRESS IN CHRONIC RENAL FAILURE AND HYPERTESION: ROLE OF ADVANCED OXIDATION PROTEIN PRODUCTS (AOPP). ... OXIDATIVE STRESS IN CHRONIC RENAL FAILURE AND HYPERTESION: ROLE OF ADVANCED OXIDATION PROTEIN PRODUCTS (AOPP) ...
more infohttps://iris.unime.it/handle/11570/1942246
Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK-NF-κB...  Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK-NF-κB...
Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK-NF-κB- ... Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK-NF-κB- ... Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK-NF-κB- ... To determine whether advanced oxidation protein products AOPPs can induce the expression of chemokine monocyte chemoattractant ...
more infohttp://libros.duhnnae.com/2017/jul5/150008275523-Sesquiterpene-Lactones-Inhibit-Advanced-Oxidation-Protein-Product-Induced-MCP-1-Expression-in-Podocytes-via-an-IKK-NF-B-Dependent-Mechanism.php
Plus it  Plus it
Advanced Oxidation Protein Products. Advanced oxidation protein products (AOPPs) are plasma compounds preferentially formed ... Increased level of advanced oxidation protein products in patients with coronary artery disease. Atherosclerosis 2002;162:221- ... Concentration of total (free + protein bound) plasma nitrotyrosine, as an end product of protein nitration by peroxynitrite ( ... Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats. J Clin Invest 1996;97:238-243 ...
more infohttp://care.diabetesjournals.org/content/38/11/2120
Caffeic acid rich Citrus macroptera peel powder supplementation prevented oxidative stress, fibrosis and hepatic damage in CCl4...  Caffeic acid rich Citrus macroptera peel powder supplementation prevented oxidative stress, fibrosis and hepatic damage in CCl4...
Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int. 1996;49:1304-13.CrossRefPubMed ... Advanced protein oxidation products (APOP) assay:. APOP levels were measured by a modification of the method of Witko-Sarsat et ... APOP-Advanced protein oxidation product expressed as nmol/mL equivalent to Chloramine-T ... ROOH and helps against protein oxidation [41]. Our study revealed that administration of oral CCl4 reduced the amount of anti- ...
more infohttps://link.springer.com/article/10.1186/s40816-018-0074-y
Frontiers | Estrogen Therapy Worsens Cardiac Function and Remodeling and Reverses the Effects of Exercise Training After...  Frontiers | Estrogen Therapy Worsens Cardiac Function and Remodeling and Reverses the Effects of Exercise Training After...
... and antioxidant protein expression by Western blotting and antioxidant enzyme activity in the heart were evaluated. The MI ... and antioxidant protein expression by Western blotting and antioxidant enzyme activity in the heart were evaluated. The MI ... Moreover, histological analyses of the heart (collagen and hypertrophy), cardiac oxidative stress (advanced oxidation protein ... Moreover, histological analyses of the heart (collagen and hypertrophy), cardiac oxidative stress (advanced oxidation protein ...
more infohttps://www.frontiersin.org/articles/10.3389/fphys.2018.01242/full
Caffeic acid rich Citrus macroptera peel powder supplementation prevented oxidative stress, fibrosis and hepatic damage in CCl4...  Caffeic acid rich Citrus macroptera peel powder supplementation prevented oxidative stress, fibrosis and hepatic damage in CCl4...
Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int. 1996;49:1304-13.CrossRefPubMed ... Advanced protein oxidation products (APOP) assay:. APOP levels were measured by a modification of the method of Witko-Sarsat et ... APOP-Advanced protein oxidation product expressed as nmol/mL equivalent to Chloramine-T ... ROOH and helps against protein oxidation [41]. Our study revealed that administration of oral CCl4 reduced the amount of anti- ...
more infohttps://rd.springer.com/article/10.1186/s40816-018-0074-y
Frontiers | iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis |...  Frontiers | iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis |...
A) Advanced Oxidation Protein Product (AOPP) concentrations in sera from HOCl-mice and HOCl-mice treated with 2.5 × 105 WT-, or ... Determination of Advanced Oxidation Protein Product (AOPP) Concentrations in Sera. AOPP concentration was measured by ... Radical oxygen species production induced by advanced oxidation protein products predicts clinical evolution and response to ... Selective oxidation of DNA topoisomerase 1 induces systemic sclerosis in the mouse. J Immunol. (2009) 182:5855-64. doi: 10.4049 ...
more infohttps://www.frontiersin.org/articles/10.3389/fimmu.2018.03056/full
Nutrients  | Free Full-Text | The Potential Benefits of Red Beetroot Supplementation in Health and Disease | HTML  Nutrients | Free Full-Text | The Potential Benefits of Red Beetroot Supplementation in Health and Disease | HTML
... advanced oxidation protein products; IL-6, interleukin-6. Gy, gray unit; LDH, lactate dehydrogenase; ALT, alanine ... Providing rats beetroot juice (8 mL∙kg∙bm∙day−1) for 28 days was shown to attenuate lipid peroxidation, protein oxidation and ... protein and lipid structures susceptible to oxidation and functional impairments [45,46,47]. ... NF-κB, nuclear factor kappa B; NP-SH, non-protein sulfhydryl; DMBA, 7,12-dimethylbenz[a]anthracene; NQO1, NAD(P)H dehydrogenase ...
more infohttps://www.mdpi.com/2072-6643/7/4/2801/htm
Healthcare  | Free Full-Text | Comparison of a Restricted and Unrestricted Vegan  Diet Plan with a Restricted Omnivorous Diet...  Healthcare | Free Full-Text | Comparison of a Restricted and Unrestricted Vegan Diet Plan with a Restricted Omnivorous Diet...
C-reactive protein, and oxidative stress biomarkers (malondialdehyde, advanced oxidation protein products, and nitrate/nitrite ... This is true whether individuals eliminate all animal products or include small amounts of meat and dairy in their plan. The ... Aliquots for the protein oxidation marker known as advanced oxidation protein products (AOPP; using reagents purchased from ... C-reactive protein, and oxidative stress biomarkers (malondialdehyde, advanced oxidation protein products, and nitrate/nitrite ...
more infohttp://mdpi.com/2227-9032/3/3/544/htm
A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes | Clinical Science  A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes | Clinical Science
advanced oxidation protein product; ARB, angiotensin type 1 receptor blocker; ASMC, aortic smooth muscle cell; CKD, chronic ... nucleotide-binding oligomerization domain-containing protein 2; NOX, NADPH oxidase; PFD, pirfenidone; PKC, protein kinase C; ... monocyte chemoattractant protein-1; mtROS, mitochondrial ROS; NF-κB, nuclear factor kappa-light-chain-enhancer of activated B ...
more infohttp://www.clinsci.org/content/132/16/1811
Parathyroid hormone - Wikipedia  Parathyroid hormone - Wikipedia
"Infection and Immunity Immunophenotyping (3i) Consortium". Drüeke TB, Massy ZA (2003). "Advanced oxidation protein products, ... PTH was one of the first hormones to be shown to use the G-protein, adenylyl cyclase second messenger system. PTH reduces the ... PTH is secreted when [Ca2+] is decreased (Calcitonin is secreted when serum calcium levels are elevated). The G-protein coupled ... In the parathyroid gland, high concentrations of extracellular calcium result in activation of the Gq G-protein coupled cascade ...
more infohttps://en.wikipedia.org/wiki/Parathyroid_hormone
Protective effects of Cynara scolymus leaves extract on metabolic disorders and oxidative stress in alloxan-diabetic rats | BMC...  Protective effects of Cynara scolymus leaves extract on metabolic disorders and oxidative stress in alloxan-diabetic rats | BMC...
Advanced oxidation protein product. AST & ALT: Aspartate and lactate transaminase. b.w: body weight ... Kayali R, Cakatay U, Akcay T, Altug T. Effect of alpha-lipoic acid supplementation on markers of protein oxidation in post- ... mg protein) and the protein estimation was carried out by means of Lowry et al. [37] method using bovine serum albumin as the ... these free radicals are then involved in the oxidation of RBC's membrane proteins and lipids that make them susceptible to ...
more infohttps://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-017-1835-8
Associations of the GCLC RS10948751 genotype with the P | Open-i  Associations of the GCLC RS10948751 genotype with the P | Open-i
Background: Advanced oxidation protein products (AOPP) are newly identified efficient oxidative stress biomarkers. In a ... Background: Advanced oxidation protein products (AOPP) are newly identified efficient oxidative stress biomarkers. In a ... Plasma advanced oxidative protein products are associated with anti-oxidative stress pathway genes and malaria in a ... Plasma advanced oxidative protein products are associated with anti-oxidative stress pathway genes and malaria in a ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4230024_1475-2875-13-134-4&req=4
人基质γ羧基谷氨酸蛋白(MGP)ELISA试剂盒 中  人基质γ羧基谷氨酸蛋白(MGP)ELISA试剂盒 中
Human advanced oxidation protein products,AOPP ELISA kit EK1063 人丝狀血球凝集素(FHA)ELISA试剂盒 Human filamentous hemagglutinin,FHA ELISA ... Human hemoglobin-advanced glycosylation end products,Hb-AGE ELISA kit EK0942 人血红蛋白β亚基(HB-β)ELISA试剂盒 Human β-subunits of ... Human advanced glycation end products,AGEs ELISA kit EK0974 人分泌型免疫球蛋白A(SIgA)ELISA试剂盒 Human secretory immunoglobulin A,SIgA ... Human Mannma binding protein/mannan binding lectin,MBP/MBL ELISA kit
more infohttps://www.caigou.com.cn/product/201605061713.shtml
Parathyroid hormone - Wikipedia  Parathyroid hormone - Wikipedia
Drüeke TB, Massy ZA (2003). "Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia". ... nor does it indicate the calcium that is bound to the extracellular proteins (in particular the plasma proteins) or to plasma ... Click on genes, proteins and metabolites below to link to respective articles. [§ 1] ... protein N-terminus binding. • receptor ligand activity. • peptide hormone receptor binding. • RNA polymerase II transcription ...
more infohttps://en.m.wikipedia.org/wiki/Parathyroid_hormone
Parathormona - Wikipedia, a enciclopedia libre  Parathormona - Wikipedia, a enciclopedia libre
Drüeke TB, Massy ZA (2003). "Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia". ...
more infohttps://gl.wikipedia.org/wiki/Parathormona
Paratiroidni hormon - Википедија, слободна енциклопедија  Paratiroidni hormon - Википедија, слободна енциклопедија
Drüeke TB, Massy ZA (2003). „Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia". ...
more infohttps://sr.wikipedia.org/wiki/Paratiroidni_hormon
  • Administration of CCl 4 increased the serum ALT, AST, ALP enzymatic activities and lipid peroxidation products but decreased the cellular antioxidant activities and reduced glutathione (GSH) levels in rats which were brought back to near normal levels by the treatment with Citrus macroptera . (springer.com)
  • GO is formed by lipid peroxidation and the degradation of monosaccharides, saccharide derivatives and glycated proteins. (mdpi.com)
  • Additionally, MGO can also be formed as a side-product of different metabolic pathways (e.g., by enzymatic elimination of phosphate from glycerone phosphate, glyceraldehyde 3-phosphate or from 3-aminoacetone in the threonine catabolism, during lipid peroxidation and from the degradation of DNA) [ 2 ]. (mdpi.com)
  • Erythrocyte sedimentation rate, leucocytes counts, serum C-reactive protein, neutrophil, and serum lipid peroxidation and intracellular Ca2+ release levels were higher in active and inactive groups than in the control group, although their levels were lower in active group than in inactive group. (deepdyve.com)
  • Contrast-agent-induced nephropathic changes are more closely related to the magnitude of lipid peroxidation than protein oxidation. (ircmj.com)
  • The diagram does not show the extremely small amounts of calcium that move into and out of the cells of the body, nor does it indicate the calcium that is bound to the extracellular proteins (in particular the plasma proteins) or to plasma phosphate. (wikipedia.org)
  • High mobility group box-1 (HMGB1) protein was originally characterized as a nuclear DNA-binding protein, and was described to have an extracellular role when involved in cellular activation and proinflammatory responses. (jimmunol.org)
  • We identified a significant increase in the amount of acute phase protein serum amyloid A1, albumin, lipoprotein-associated phospholipase A2, and apoC-III composing uremic HDL. (asnjournals.org)
  • In the present study, we have found that the proinflammatory activity of recombinant HMGB1 proteins is determined by the containing endotoxin level, and HMGB1 that contains few endotoxins fails to stimulate macrophages to secrete proinflammatory cytokines. (jimmunol.org)
  • In our study, we have found that the proinflammatory activity of recombinant HMGB1 protein is correlated with the endotoxin level it contained, and that HMGB1 significantly enhances the activity of LPS to induce proinflammatory cytokines both in vitro and in vivo by promoting the phosphorylation of MAPK p38 and the activation of NF-κB through RAGE. (jimmunol.org)
  • Functional impairment of HDL may contribute to the excess cardiovascular mortality experienced by patients with renal disease, but the effect of advanced renal disease on the composition and function of HDL is not well understood. (asnjournals.org)
  • 20 However, data available regarding the effect of advanced renal disease on HDL functionality are limited, and the effects of renal disease on the first step of reverse cholesterol transport, the efflux of cellular cholesterol from macrophages to HDL, have not been established yet. (asnjournals.org)
  • 21 Accordingly, to understand the role of HDL in chronic and inflammatory diseases, as end-stage renal disease, it is essential to analyze the protein and lipid composition of HDL to reflect its functional state. (asnjournals.org)
  • Larger, extracellularly derived AGE proteins cannot pass through the basement membrane of the renal corpuscle and must first be degraded into AGE peptides and AGE free adducts. (wikipedia.org)
  • The high mobility group box-1 (HMGB1) 4 that was first discovered as a nuclear protein with rapid electrophoretic migration was a 30 kDa, nonhistone, DNA-binding molecule that was highly conserved. (jimmunol.org)
  • Methanogenesis effectively removes the semi-final products of decay: hydrogen, small organics, and carbon dioxide. (wikipedia.org)