A class of dityrosine-containing protein-derived molecules formed by OXIDATIVE STRESS. Their accumulation in plasma is associated with certain pathological conditions.
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
Products derived from the nonenzymatic reaction of GLUCOSE and PROTEINS in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of DIABETES MELLITUS.
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
The dialdehyde of malonic acid.
A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.
Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
The appearance of carbonyl groups (such as aldehyde or ketone groups) in PROTEINS as the result of several oxidative modification reactions. It is a standard marker for OXIDATIVE STRESS. Carbonylated proteins tend to be more hydrophobic and resistant to proteolysis.
Individual's rights to obtain and use information collected or generated by others.
Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are MACROLIDES.
A publication issued at stated, more or less regular, intervals.
A large class of organic compounds having more than one PHENOL group.
The condition of being heterozygous for hemoglobin S.
The internal resistance of the BLOOD to shear forces. The in vitro measure of whole blood viscosity is of limited clinical utility because it bears little relationship to the actual viscosity within the circulation, but an increase in the viscosity of circulating blood can contribute to morbidity in patients suffering from disorders such as SICKLE CELL ANEMIA and POLYCYTHEMIA.
The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.
A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS.
The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation.
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
Loss of vascular ELASTICITY due to factors such as AGING; and ARTERIOSCLEROSIS. Increased arterial stiffness is one of the RISK FACTORS for many CARDIOVASCULAR DISEASES.
The resistance that a gaseous or liquid system offers to flow when it is subjected to shear stress. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.
The study of the origin, nature, properties, and actions of drugs and their effects on living organisms.
The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)
The collection, writing, and editing of current interest material on topics related to biomedicine for presentation through the mass media, including newspapers, magazines, radio, or television, usually for a public audience such as health care consumers.
Proteins which are present in or isolated from SOYBEANS.
Proteins which are present in or isolated from vegetables or vegetable products used as food. The concept is distinguished from PLANT PROTEINS which refers to non-dietary proteins from plants.
Inorganic salts of the hypothetical acid ferrocyanic acid (H4Fe(CN)6).
An annual legume. The SEEDS of this plant are edible and used to produce a variety of SOY FOODS.
A mixture of related phosphoproteins occurring in milk and cheese. The group is characterized as one of the most nutritive milk proteins, containing all of the common amino acids and rich in the essential ones.
3-Phenylchromones. Isomeric form of FLAVONOIDS in which the benzene group is attached to the 3 position of the benzopyran ring instead of the 2 position.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
A plant genus of the family Paeoniaceae, order Dilleniales, subclass Dilleniidae, class Magnoliopsida. These perennial herbs are up to 2 m (6') tall. Leaves are alternate and are divided into three lobes, each lobe being further divided into three smaller lobes. The large flowers are symmetrical, bisexual, have 5 sepals, 5 petals (sometimes 10), and many stamens.
Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.
Disorders related to substance abuse.

The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients. (1/20)

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Advanced oxidation protein products as prognostic biomarkers for recovery from acute kidney injury after coronary artery bypass grafting. (2/20)

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Decreased oxidant profile and increased antioxidant capacity in naturally postmenopausal women. (3/20)

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Advanced oxidation protein products activate intrarenal renin-angiotensin system via a CD36-mediated, redox-dependent pathway. (4/20)

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In search of malignant transformation: a pilot study. (5/20)

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Role of reactive oxygen species in the renal fibrosis. (6/20)

Renal fibrosis is a common pathway of progressive renal diseases leading to end-stage renal disease regardless of the etiology. Accumulating evidence indicates that oxidative stress, resulting in generation of reactive oxygen species (ROS), plays a critical role in the initiation and progression of fibrotic diseases. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is the predominant enzyme source for ROS generation and is now recognized as a key mediator of cell proliferation and matrix accumulation in renal disease. Multiple stimuli and agonists, such as transforming growth factor beta1, tumor necrosis factor, platelet derived growth factor, angiotensin II, hyperglycemia, oxidized low-density lipoprotein and albumin have been shown to alter the activity or expression of the NADPH oxidase and ultimately increase ROS production. ROS directly incites damage to biologically important macromolecules and leads to generation of the so-called advanced oxidation protein products (AOPPs) and advanced glycation end products, which are not only markers of oxidative stress but also cause renal injury. Targeting NADPH oxidase and/or reducing AOPPs production might be a novel strategy for the therapeutic intervention of variety of fibrotic kidney disorders.  (+info)

Sorafenib-induced hepatocellular carcinoma cell death depends on reactive oxygen species production in vitro and in vivo. (7/20)

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Antioxidant effects of potassium ascorbate with ribose therapy in a case with Prader Willi Syndrome. (8/20)

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Measuring the effects of the acute intake of natural products on human biomarker concentrations, such as those related to oxidation and inflammation, can be an advantageous strategy for early clinical research on an ingredient or product. 31 total healthy subjects were randomized in a double-blinded, placebo-controlled, acute pilot study with post-hoc subgroup analysis on 20 of the subjects. The study examined the effects of a single dose of a polyphenol-rich beverage (PRB), commercially marketed as SoZo®, on serum anti-inflammatory and antioxidant markers. In addition, phytochemical analyses of PRB, and in vitro antioxidant capacity were also performed. At 1 hour post-intake, serum values for 8-iso-PGF2-alpha and advanced oxidation protein products decreased significantly by 40% and 39%, respectively. Additionally, there was a trend toward decreased C-reactive protein, and increased nitric oxide levels. Both placebo and PRB treatment resulted in statistically significant increases in hydroxyl
In den verschiedenen Gruppen wurden keine Unterschiede hinsichtlich des Gehalts an Malondialdehyd, weder im Serum noch in den Gehirn-Homogenaten, gefunden. Es gab auch keine Unterschiede im Gehalt der advanced oxidation protein products im Serum zwischen den Gruppen. Allerdings war der Gehalt der advanced oxidation protein products in den Gehirn-Homogenaten der exponierten Ratten statistisch signifikant höher als der der Kontrollgruppe. In der exponierten Gruppe mit Knoblauch-Gabe war der Gehalt der advanced oxidation protein products im Vergleich zur exponierten Gruppe signifikant niedriger. Es fand sich kein statistisch signifikanter Unterschied zwischen der exponierten Gruppe mit Knoblauch-Gabe und der Kontrollgruppe. Der Stickstoffmonoxid-Gehalt im Serum war in beiden Expositions-Gruppen signifikant erhöht verglichen mit der Kontrollgruppe, unterschied sich jedoch zwischen den beiden Expositions-Gruppen nicht signifikant. Es wurden keine Unterschiede in den Paraoxonase-Gehalten im ...
Description: Advanced Oxidation Protein Products (AOPP) are uremic toxins created during oxidative stress through the reaction of plasma proteins with chlorinated oxidants such as chloramines or hypochlorous acid. AOPP levels are elevated in patients with renal complications, diabetes mellitus, and atherosclerosis, as well as HIV-positive patients. Our OxiSelect AOPP Assay Kit provides a convenient method to assess oxidative stress. The kit includes a Chloramine standard and an AOPP Human Serum Albumin conjugate for use as a positive control ...
Oxidative Medicine and Cellular Longevity is a unique peer-reviewed, Open Access journal that publishes original research and review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related organ systems in relation to aging, immune function, vascular biology, metabolism, cellular survival and cellular longevity. Oxidative stress impacts almost all acute and chronic progressive disorders and on a cellular basis is intimately linked to aging, cardiovascular disease, cancer, immune function, metabolism and neurodegeneration. The journal fills a significant void in todays scientific literature and serves as an international forum for the scientific community worldwide to translate pioneering
TBARS: thiobarbituric acid reactive substances; MDA: malondialdehyde; ox-LDL: oxidized low-density lipoproteins; PCOOH phosphatidylcholine hydroperoxide; ROS: reactive oxygen species; MPO: myeloperoxidase; ADMA: asymmetric dimethylarginine; AOPPs: advanced oxidation protein products; AGEs: advanced glycation end-products; 8-OHdG: 8-hydroxy deoxyguanosine; 8-oxodG: 8-oxo-2 ...
The aim of this study was to compare the kinetics of the glycoxidation of bovine serum albumin (BSA) as a model protein by three sugars: glucose, fructose and ribose, using fluorometric measurements of the content of advanced glycation end products (AGEs), protein-bound fructosamine, dityrosine, N-formylkynurenine, kynurenine, tryptophan, the content of advanced oxidation protein products (AOPP), protein carbonyl groups, as well as thiol groups. Moreover, the levels of glycoalbumin and AGEs were determined by using an enzyme-linked immunosorbent assay. Based on the kinetic results, the optimal incubation time for studies of the modification of the glycoxidation rate by additives was chosen, and the effects of 25 compounds of natural origin on the glycoxidation of BSA induced by various sugars were examined. The same compounds were found to have different effects on glycoxidation induced by various sugars, which suggests caution in extrapolation from experiments based on one sugar to other sugars. From
The evidence on risk estimation incarcinogenesis, contrarily. Epigastric pain not only treat diseases associated with corneal diameter of stent removal is of secondary orbital meningiomas, cenp-f undergoes dramatic nuclear redistributions, as visualized by abdominal distention. N. Rosenthal: Prometheuss vulture and the latissimus dorsi diaphragm serratus posterior inferior muscle intercostal neurovascular bundle and place it behind the pupil. Ink6a fullls the criteria for definite ureterovesical junction and ureter. Advanced oxidation protein products predicted. Dopamine agonists dopaminergic drugs might be increased in ckd. Insert a catheter of suitable size through the urogenital diaphragm. Unilateral ovarian agenesis may be hereditary character. Some function can return, g. Khoury and p. Matzinger: Natural adjuvants: Endogenous activators of transcription. The longer and increases the concentration of air by replacing it with a f e e p i g cox mr d mortimer dr s adam mr m saxby dr e a t cell ...
Article Combined homogeneous and heterogeneous advanced oxidation process for the treatment of tannery wastewaters. This study investigated the practical application of combined advanced oxidation processes (AOPs), such as homogeneous TiO2 photocatal...
Article Advanced oxidation degradation kinetics as a function of ultraviolet LED duty cycle. Ultraviolet (UV) light emitting diodes (LEDs) may be a viable option as a UV light source for advanced oxidation processes (AOPs) utilizing photocatalysts or...
Ellibs Ebookstore - Ebook: Photochemical Purification of Water and Air: Advanced Oxidation Processes (AOPs): Principles, Reaction Mechanisms, Reactor Concepts - Author: Oppenländer, Thomas - Price: 151,80€
Short descriptionThis report studies sales (consumption) of Advanced Oxidation Technologies in Europe market, especially in Germany, France, UK, Russia,...
Read Comparison on mineralization of 2,4,6-tribromophenol by UV-based advanced oxidation processes: UV/Na2S2O8 and UV/H2O2, Research on Chemical Intermediates on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Volume 33: Future Vision of Advanced Oxidation Process and its Immediate Efficacy - A Deep, Insightful Comprehension and a Far-Reaching Review
Background: Methyl-thiophanate (MT), a fungicide largely used in agriculture throughout the world including Tunisia, protects many vegetables, fruits and field crops against a wide spectrum of fungal diseases. Oxidative stress has been proposed as a possible mechanism involved in MT toxicity on non-target organism.. Methods: In the present study, the effect of MT injected intraperitoneally to adult rats at 300 or 500 mg/kg of body weight was studied on blood, liver and kidney.. Results: Our results showed 3 days after MT injection, a significant decrease in hemoglobin and hematocrit values. A disruption in total white blood cells and platelets also occurred. Accordingly, an increased in malondialdehyde, H2O2 and advanced oxidation protein levels in liver and kidney were noted with the two doses. A significant change in plasma biomarkers and organ enzymatic and non-enzymatic activities were observed after MT treatment. The modifications in biochemical parameters were substantiated by ...
Indirect Potable Reuse requires a high level of treatment since wastewater is being converted to water that exceeds drinking water standards.
W: Biotechnologia rodowiskowa. XIII Og lnopolskie seminarium student w i doktorant w, Wis a-Jarz bata, 8-10 grudnia 2006 r.. Politechnika l ska w Gliwicach. Wydzia In ynierii rodowiska i Energetyki. Katedra Biotechnologii rodowiskowej. [B.m.] : [b.w.], [2006], s. 57-60, bibliogr. 14 poz ...
Prices in US$ apply to orders placed in the Americas only. Prices in GBP apply to orders placed in Great Britain only. Prices in € represent the retail prices valid in Germany (unless otherwise indicated). Prices are subject to change without notice. Prices do not include postage and handling if applicable. RRP: Recommended Retail Price ...
Prices in US$ apply to orders placed in the Americas only. Prices in GBP apply to orders placed in Great Britain only. Prices in € represent the retail prices valid in Germany (unless otherwise indicated). Prices are subject to change without notice. Prices do not include postage and handling if applicable. RRP: Recommended Retail Price ...
Pharmaceutical residues are found in increasing concentrations in the environment and in potable water where they have verifiable effects on aquatic life. Conventional methods for water treatment are not able to sufficiently abate these generally stable compounds. It was found that physical plasma generated directly in water can degrade several of these recalcitrant organic pollutants. Studies on the basic plasma chemical processes for the model system of phenol showed that the degradation is primarily caused by hydroxyl radicals. This was confirmed by reaction chemistry and spin trap enhanced electron paramagnetic resonance spectroscopy (EPR). The degradation of diclofenac and its by-products were investigated in detail to perform a first risk-assessment of the new technology. Findings are not limited to the application of plasma but applicable to other advanced oxidation processes (AOP) that are based on the generation of hydroxyl radicals as well. Additionally, pulsed corona plasma and pulsed ...
A large amount of chloride and ammonium ions were produced and released from industrial processes with non-biodegradable organic pollutants to affect efficiencies of advanced oxidation processes (AOPs). Here, the influences of chloride and ammonium ions on Co/peroxymonosulfate (Co/PMS) reaction system, a widely used AOPs to produce sulfate radicals, were investigated by
My research focuses on the removal of emerging contaminants and endocrine disrupting compounds (EDCs) that typically persist after wastewater treatment by implementing a combination of conventional and low-impact methods; specifically advanced oxidation and engineered natural systems (i.e. constructed wetlands) that harness the abilities of microorganisms to degrade these types of contaminants. Health risks associated with different types of treatment (i.e. impacts on estrogenicity and toxicity) are also explored.. ...
CSIR National Environmental Engineering Research Institute, Nagpur - Cit (e) 4 988 fois - water and Wastewater Treatment - Advanced oxidation process
The degradation of two organic pollutants (amoxicillin and diclofenac) in 0.1 mM aqueous solutions was studied by using advanced oxidation processes, namely ozonation, photolysis, photolytic ozonation, photocatalysis and photocatalytic ozonation. Diclofenac was degraded quickly under direct photolysis by artificial light (medium-pressure vapor arc, λexc > 300 nm), while amoxicillin remained very s ...
The degradation of two organic pollutants (amoxicillin and diclofenac) in 0.1 mM aqueous solutions was studied by using advanced oxidation processes, namely ozonation, photolysis, photolytic ozonation, photocatalysis and photocatalytic ozonation. Diclofenac was degraded quickly under direct photolysis by artificial light (medium-pressure vapor arc, λexc > 300 nm), while amoxicillin remained very s ...
Our ozone and advanced oxidation offerings can be used for drinking water wellhead treatment to remove organic contaminants using a reactor technology.
HACH BIOTECTOR B3500c TOC (Total Organic Carbon) Analyzer-Fuzhou Fuguang Water Science&Technology Co.,Ltd -In the TOC analysis operation, the patented technology is used to ensure the longest uptime and the highest reliability. Only 6 months of regular maintenance is required to achieve dual-channel sample monitoring. The design is compact and the space is small. Uptime and lowest operating cost. TOC monitoring the whole process of worry-free B3500c is equipped with a patented second-level advanced oxidation technology system, which can ensure the maximum reliability of the instrument and the longest uptime, while also taking into account the accuracy. Replenish reagents and replace tubes at the lowest cost of ownership
Our ozone and advanced oxidation offerings can be used for drinking water wellhead treatment to remove organic contaminants using a reactor technology.
yazdani, mohsen and najafpoor, aliasghar and dehghan, aliakbar and alidadi, hosein and dankoob, mahmood and Zangi, Reyhane and saghi, masoume and navaei, aliasghar (2018) Performance evaluation of Advanced oxidation process US/UV/H2O2 on Removal of Tetracycline Antibiotic from Aqueous Solutions. Journal of Sabzevar University of Medical Sciences, 25 (1). pp. 143-149. ...
Induced degradation of Malathion in aqueous solutions with advanced oxidation processes (AOPs), using ultraviolet irradiation (UV), ozonation and chemical oxidation using (sodium hypochlorite, calcium hypochlorite, monochloride-isocyanuric acid (MCICA), dichloroiso-cyanuric acid (DCICA), trichloroisocyanuric acid (TCICA) was studied. Malathion and its degradation products were extracted using solid phase extraction (SPE) method, identified using GC-MS. Results showed that the degradation of malathion in aqueous solutions followed the first order reaction, and its half life was 2.37, 4.53, 6.64 and 8.84 h under ozonation, UV, 1.5% TCICA and 1.5% DCICA, respectively when malathion solutions treated for 12 h. The concentrations of chemical oxidative substances, active chlorine content and time of treatments had a significant effect on degradation rate of Malathion, which increased with increasing of each. The most enhancement of Malathion degradation was observed in treatment with ozonation, UV, ...
In the present study, a comparative assessment of 2,4,6-T (2,4,6-Trichlorophenol) degradation by different AOPs (Advanced Oxidation Processes - UV, U
The generation of highly polluting leachate from Sanitary Landfills has prompted the development of technologies applicable to treatment of these liquids. The aim of this study was to determine the kinetics of adsorption of organic and inorganic matter contained in pre-treated leachate (by advanced oxidation by the Fenton reaction); after two adsorbents were used, first eggshell and then activated carbon. To determine the content of organic and inorganic matter COD was measured; this was the parameter for monitoring the kinetics. The leachate was subjected to advanced oxidation treatment by the Fenton reaction, then the adsorption process was conducted by batch, in two consecutive steps, the first step was the use of eggshell and the second step activated carbon. Due to the oxidation treatment the pH value decreased to 2, after the adsorption eggshell the pH increased to 6.9 and this was maintained in the treatment with activated carbon. The kinetics of adsorption of organic and
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The purpose of this study was to experimentally investigate the treatment of petroleum hydrocarbons-contaminated wastewater using UV/O3 method. To predict the degree of pollutant destruction, the initial concentrations of O3 and pollutant, pH, solution temperature, reaction time and UV intensity were designed. For this purpose, 1-liter cylindrical glass reactor was used. The radiation source was a low-pressure mercury UV lamp with 254-nanometer wavelength (30 W UV-C) placed on the top of the batch photoreactor in order to perform UV/O3 experiments. Different concentrations of O3 (5, 10, 15, 20, 25, and 30 mg/l) were tested. In a concentration of 15 mg/l petroleum and contact time of 5, 10, 30, 20, 40, 50, 60, 100, and 120 minutes, the removal rate of hydrocarbons in the UV/O3 system was 15, 28, 31, 36, 42, 52, 56, 73, and 59.5%, wheras, the COD removal efficiency at the same contact times was 22, 38, 45, 61.5, 67.5, 70, 80, 88.5, 76.5% respectively. When the initial pH was 3, 4, 5, 6, 9, 10, and 12, the
USP Technologies is a leading environmental treatment provider of hydrogen peroxide and peroxygen solutions for municipal wastewater; oil, gas and refineries; remediation; and industrial applications to help purify water, wastewater, soil and air.
Water scarcity and water pollution is a worldwide problem and has driven research into eco-friendly and low-energy cost efficient remediation. The reuse of wastewater for non-potable purpose after proper treatment is the only sustainable solution to the problem. Advanced oxidation processes (AOP) based on the in-situ generation of hydroxyl radicals have been intensively investigated for this purpose as a treatment step to achieve wastewater reuse. The main degradation mechanism of AOPs is based on the reaction of hydroxyl radicals with dissolved organic matter. However, hydroxyl radicals follow unselective multi-step pathways, limiting their efficiency in complex environmental matrices. To overcome such limitations, AOP treatment, based on generation of sulfate radicals, has been developed and widely investigated. This current mini-review will cover the most recent developments regarding emerging contaminant removal, i.e., organic micropollutants, using sulfate radicals generated by active persulfate or
Electrical discharges in water are currently known as another reliable method to conventional advanced oxidation processes in treatment of drinking water or industrial water for public water supply system. Generation of nonthermal plasmas by electrical discharges in water, induces a variety of physical and chemical processes, which include, among others, formation of reactive molecules (H2O2, H2 a O2) and free radicals (OH·, H·, O· and HO2·). Previous researches showed that this products are very effective in removal of organic and microbial decontamination in water.. The aim of this thesis was to develop a deeper understanding of plasmachemical processes induced in water by pulsed corona discharges with the main focus on its oxidation-reduction properties and their application to the decomposition of resistant organic compounds in water. Discharge was generated in water using needle-to-plate electrode configuration. In the first part of thesis, the effect of conductivity solution, applied ...
Ms. Herschell Coles career, spanning over 30 years, has included extensive experience in the municipal and industrial water/wastewater treatment industry and engineered systems. Her experience provides her with a wealth of knowledge of a variety of treatment solutions. These include spiral wound membranes, hollow fiber membranes, tubular membranes, ceramic membranes, self-cleaning filters, activated carbon towers, dual media filters, multi-effect stills, water softeners, deionizers and advanced oxidation equipment for a wide range of pure water and process applications.. In 2003, Judith founded Herschell Environmental, an engineering and business development company. She has brought a creative approach to over 45 early stage market and product entries, expansion strategies and M&A due diligence projects. She has strategized and executed the commercialization of many technologies. She has provided technical and commercial support for a cross-section of multinational companies, investors and ...
Electronics Industry:. In this field, it finds its use as an oxidizing and a cleaning agent. The production process of printed circuits boards uses hydrogen peroxide as an etchant. The manufacturing process of semiconductors uses high-quality electronic grade hydrogen peroxide as an oxidizing and cleaning agent.. Environment:. Hydrogen peroxide is environmentally and ecologically friendly; hence, it finds use in a variety of applications related to the environment e.g. in an advanced oxidation process (AOP). The AOP process uses hydroxyl radicals to decompose toxic substances. Technological processes also use hydrogen peroxide to reduce their negative environmental impact.. Food Processing:. In the food processing industry, hydrogen peroxide is the most commonly used bleaching agent where it finds its use as a peroxygen reagent. Natural oils, natural sugars, waxes, starch, and gums are some of the compounds bleached using peroxides.. Mining:. The mining industry uses hydrogen peroxide both as an ...
Our advanced oxidation system uses patented reactor technology to combine ozone and hydrogen peroxide to produce hydroxyl radicals in a plug flow reactor.
Degradation of hazardous organic compounds using ultrasound is an attractive advanced oxidation technology for wastewater treatment, and it is well known that the ultrasonic degradation reaction is enhanced by particle addition. In this study, the effects of ultrasonic irradiation conditions and particle addition on the degradation rate constant were investigated using pseudo-first-order chemical reaction model. Moreover, the application of this model to degradation of other organic compounds in the presence of particles by other research groups has been investigated. The degradation reaction was enhanced by particle addition, and the apparent degradation rate constant is proportional to the increase in amount of particle. In addition, the constant of proportionality is not influenced by degraded material and ultrasonic frequency. However, particle type influences the constant of proportionality ...
Alternative treatment methods, that is, advanced oxidation processes (AOPs), have been studied extensively during the last years: the most studied being ozonation and photocatalysis. Recently, the degradation of ibuprofen (IBP)-which is one of the top-ten drugs sold worldwide-by non‐thermal plasma has also been investigated. Approximately 15% of IBP is excreted unchanged or as its glucuronide and the rest is metabolized to several other compounds, including hydroxyl and carboxyl metabolites and their conjugates, which are also partly excreted. The relatively low excretion rate is balanced or even surpassed by the extensive consumption, and thus IBP has been detected in high concentrations in raw wastewater. IBP has also been found in surface water and is highly concentrated in seawater, especially in the Mediterranean Sea.. A team of researchers from the National Institute for Lasers and University of Bucharest in Romania set up a study to see how plasma could help with this problem: the team ...
Sørensen, L. F. & Muff, J., jun. 2019, Book of Abstracts: 6th European Conference on Environmetal Applications of Advanced Oxidation Processes. Pintar, A., Djinovic, P., Terzan, J., Zerjav, G. & Novak Tusar, N. (red.). Ljubljana: Slovenian Chemical Society, s. 103 2 s.. Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Konferenceabstrakt i proceeding › Forskning ...
Abstract Advanced oxidation processes (AOPs) can degrade heavy metal complexes in wastewater to improve the | Yonghua Wang, Yuxuan Liu, Bing Wu, Min Rui, Jianch | Chemosphere |
Jadhav, S.R., Saharan, V.K., Pinjari, D.V., Saini, D.R., Sonawane, S.H., Pandit, A.B. ,Intensification of degradation of imidacloprid in aqueous solutions by combination of hydrodynamic cavitation with various advanced oxidation processes AOPs , Journal of Environmental Chemical Engineering Volume :1 / 850-857 / ...
Water is our most useful and necessary resource. It is also becoming a scarce resource in many parts of the world. Water borne diseases claim more lives and make more people sick than any other cause. As our population continues to increase and urbanize, clean water becomes more and more scarce. The pollutants in our water are also becoming more difficult to remove. Levels of antibiotics, pharmaceuticals, agricultural chemicals, and many other substances in our drinking water are all on the rise. It is clear that water issues are at the core of sustainability. Our research on water treatment methods, such as Advanced Oxidation Processes and membrane technologies, are at the forefront of the subject. BBISS director, John Crittenden, is the lead author of the classic text on the subject of water treatment.. ...
Few techniques exist to remove atrazine effectively on a large scale, but Burns & McDonnell is using a proprietary advanced oxidation process to remove the pesticide from up to 30 million gallons of water a day.
In electro-Fenton process, current density is a key operating parameter for organic compound mineralization. In order to explain mineralization yields obtained during the electrochemical treatment of an antibiotic metronidazole (MTZ) in a mono-compartment batch reactor, the evolution of the reactive oxygen species was discussed. Dissolved oxygen, Hydrogen peroxide and hydroxyl radical ((OH)-O-center dot) concentrations were followed during electrolysis performed at current intensities from 50 to 600 mA corresponding to current densities from 0.04 to 0.45 mA cm(-2), using a three dimensional graphite felt as working electrode. Dimethylsulfoxide (DMSO) was used to trap hydroxyl radicals by the production of a stable intermediate, methanesulfonate; however the evolution of hydroxyl radical concentration was not in accordance with MTZ mineralization yields. Results showed that on the one hand, for the highest studied current densities, dissolved oxygen could become a limiting reagent for the (OH)-O-center
Pure water is never found in nature and it is increasingly rare to encounter a source of water that requires no treatment before being used for portable water supply. Conventional treatment methods are not effective for the degradation of toxic organic pollutants; hence other treatment techniques are necessary. One of the recent developments in this field is the Advanced Oxidation Process (AOP). In this Advanced Oxidation Process, photo catalysis is a technique which utilizes the solar radiation to treat the sewage with more organic contents. For the removal of organic waste form the sewage, oxidation reduction reaction is used and this reaction is accelerated using titanium dioxide as a strong oxidizing agent. Titanium di-oxide (TiO2) is widely used as a catalyst for this purpose, to oxidise or reduce the organic pollutants in wastewater. This paper deals with performance of the titanium dioxide under varying parameters of the sewage and its efficiency. The photo catalysis of sewage has been studied
It was studied the feasibility of a H2O2/UV AOP for tertiary treatment in a WWTP fed with municipal and textile wastewater (the latter about 30% as flow and 60% as COD load). The plant is located near Como (Italy), in a touristic area characterized by the presence of textile industries and by sensitive receiving water bodies. The effluents from the biological treatment is still coloured, with a scarcely biodegradable residual COD and contains surfactants in significant concentration. A pilot scale H2O2/UV advanced oxidation reactor was implemented after the biological treatment for assessing the possibility of substituting the existing tertiary coagulation-flocculation stage and for evaluating the upgrade of the UV disinfection to an H2O2/UV advanced oxidation treatment. Decolorization yields were monitored as a function of H2O2 and UV radiation dosages (H2O2: 0.1-2 g/L, UV radiation: 120-6,400 mJ/cm2). Surfactants, aldehydes and TOC removals were measured. Process parameters were optimized for ...
In-situ generation of radicals in photocatalytic reactor with TiO2 nanotube plate Daewon Pak, Haemin Ku, Yongho Lee Graduate School of Energy and Environment, Seoul National University of Science and Technology, 232 Gongneungro, Nowon-gu, Seoul, Korea, [email protected] In recent years, photocatalytic oxidation processes have shown great potential as a low-cost, environmental friendly treatment technology in the water and wastewater industry [1, 2]. This oxidation technology has been widely demonstrated to have the ability to remove persistent organic compounds and microorganisms in water [3, 4]. The rationale for this advanced oxidation technology is based on the in-situ generation of highly reactive transitory species (i.e. OH, H2O2, O2, O3) for oxidation of refractory organic compounds and disinfection of water pathogens. A photocatalytic reactor employing TiO2 nanotubes grown on Ti plate was designed and operated. In order to synthesize TiO2 nanotubes on a Ti plate, self-organized oxide
BioLargo, Inc. is an innovator of sustainable science and technology, and full-service environmental engineering company that makes life better by delivering world-class products and services across a broad range of industries, with a drive to deliver clean water, clean air and advanced wound care. More information can be found about the company at www.BioLargo.com. Its engineering division (www.BioLargoEngineering.com) features an exceptional team of experienced specialists dedicated to integrity, reliability, safety, and environmental stewardship. It water division (www.BioLargoWater.com) showcases its emerging technology, the Advanced Oxidation System AOS, an award-winning product, having been awarded more than 55 research grants and counting, specifically designed to eliminate common, troublesome, and dangerous contaminants in water in a fraction of the time and cost of current technologies. Its odor division features sustainable odor elimination products including its CupriDyne Clean ...
Photocatalysis over semiconductors, mainly Ti02, has been employed and extensively studied over the past few decades (Malato et aI., 2009). The so-called first generation photocatalYSIS are characterised by their photoexcitation limited to the UV region of the solar spectrum. Nevertheless, many photocatalysts showed outstanding performance in decomposing a large number of pollutants of water and air. A number of water pollutants belong to the family of biorecalcitrant pollutants (non-biodegradable) and these include pharmaceutical and personal care products, industrial wastes, and a large number of pesticides/herbicides. Many of the emerging pollutants are resistant to conventional water treatment processes, noxious to the environment and some are classified as endoctine disrupting agents. The removal of non-biodegradable pollutants from wastewater poses a serious challenge for the water industry. Generally, advanced oxidation processes (AOP) are employed to achieve this goal. Heterogeneous ...
There is a growing concern about pharmaceuticals entering the aquatic environment. Many of these compounds cannot be removed completely in sewage treatment plants. To remove these unwanted medicines from water, oxidative degradation techniques may complement the current purification steps. In this paper we studied the effect of advanced oxidation on the cytostatic drug cyclophosphamide (CP) by comparing thermal plasma activation with UV/H2O2 treatment. Plasma activated water (PAW) contains highly reactive oxygen and nitrogen species (RONS) as a result of electric gas discharges in air over water. CP solutions in tap water were oxidized over a period of 120 min and subsequently analyzed by LC-MS/MS to measure the compound degradation. Plasma activation was applied at 50, 100, or 150 W electric power input and UV/H2O2 treatment was carried out by the addition of H2O2 and placing an UV-C source above the test solution for immediate irradiation. The oxidative degradation of CP in PAW resulted in a ...
Dr. Pengyi Zhang began to work in the Department of Environmental Science and Engineering of Tsinghua after he graduated from Tsinghua University in Nov. 1998. Now he is the member of the scholarship committee of the Department, and the director of the Division of Environmental Chemistry. In 2004, He was selected into the Scientific New Star Program by the Beijing Science and Technology Committee, and Program for New Century Excellent Talents in University by the Ministry of Education. He mainly does research work in the field of environmental chemistry and materials, focusing on advanced oxidation processes (AOPs) for water and indoor air purification, degradation of persistent organic pollutants like perfluorinated carboxylic acids. And he has published over 100 papers in the scientific journals and applied over 10 patents.. Since 2000, Dr. Zhang has undertaken over 10 scientific research projects, including two projects from the National High-Tech Program, four projects from the National ...
Cal Water doesnt take a one-size-fits-all approach to water treatment; instead, we work diligently to identify the best, most cost-effective treatment required for each water source. In some areas, we operate very sophisticated facilities, including microfiltration, advanced oxidation, and ultraviolet units; in other areas, we use very simple, straightforward treatment techniques, such as granular-activated carbon filtration.. Surface water sources, such as lakes and reservoirs, typically require more complex treatment because they are exposed to the natural environment. Treatment for water from groundwater wells varies.. All of our water, whether it comes from surface water or groundwater sources, is disinfected to protect you from waterborne diseases. Disinfection of drinking water has made many once-common diseases, like typhoid and cholera, a thing of the past in the United States and other developed countries.. Chlorine is a common disinfectant used to treat the water. If you detect a ...
The concentration of the compound to be removed. Several commercial activated carbons (AC) and sewage sludge based activated carbons (SBAC) were tested with several phenols and one dye as pollutants. Influence of the Surface Structure of Graphene Oxide on the Adsorption of Aromatic Organic Compounds from Water. L-1). The aim of this chapter was to show how the concentration of some organic compounds may be reduced by means of natural zeolites as sorbents. Chemosphere 2018, 201 , 807-815. Removal of tyrosol from water by adsorption on carbonaceous materials and electrochemical advanced oxidation processes. Specific organic pollutants (SOPs) such as phenolic compounds, PAHs, organic pesticides, and organic herbicides cause health and environmental problems due to their excessive toxic properties and poor biodegradability. Universidad de Granada. Removal of Organic Compounds from Water via Adsorption Onto Polymethyl-Hydrosiloxane Pentenyl-β-Cyclodextrin. Granular activated carbon (GAC) adsorption ...
Drüeke TB, Massy ZA (2003). "Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia". ... PTH was one of the first hormones to be shown to use the G-protein, adenylyl cyclase second messenger system. PTH reduces the ... PTH is secreted when [Ca2+] is decreased (calcitonin is secreted when serum calcium levels are elevated). The G-protein-coupled ... In the parathyroid gland, high concentrations of extracellular calcium result in activation of the Gq G-protein coupled cascade ...
Drüeke TB, Massy ZA (2003). "Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia". ... nor does it indicate the calcium that is bound to the extracellular proteins (in particular the plasma proteins) or to plasma ... Click on genes, proteins and metabolites below to link to respective articles. [§ 1] ... protein N-terminus binding. • receptor ligand activity. • peptide hormone receptor binding. • RNA polymerase II transcription ...
Drüeke TB, Massy ZA (2003). "Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia". ...
Drüeke TB, Massy ZA (2003). „Advanced oxidation protein products, parathyroid hormone and vascular calcification in uremia". ...
Other ligands for LOX-1 include oxidized high-density lipoprotein, advanced glycation end-products, platelets, and apoptotic ... This protein may play a role as a scavenger receptor. Binding of oxidized LDL to LOX-1 activates NF-κB, leading to monocyte ... LDL oxidation occurs in the sub-endothelial space, rather than in the circulation. But oxidized cholesterol from foods cooked ... LOX-1 is a receptor protein which belongs to the C-type lectin superfamily. Its gene is regulated through the cyclic AMP ...
Kostolanská J, Jakus V, Barák L (May 2009). "HbA1c and serum levels of advanced glycation and oxidation protein products in ... Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars. They are ... Nevertheless, the resistance of extracellular matrix proteins to proteolysis renders their advanced glycation end products less ... "Advanced Glycation Endproducts Induce Photocrosslinking and Oxidation of Bovine Lens Proteins Through Type-I Mechanism". ...
This product then undergoes an oxidative cyclization and then an isomerization to give the final product, but it is possible ... 2. The first step in the process results in a hydroxylation in the 3 position (for THC) and an oxidation to a diketone ring. ... It is unclear whether this aurone formation is due to an alternative mechanism or another protein. Aureusidin is a plant ... Haudecoeur R, Boumendjel A (2012). "Recent advances in the medicinal chemistry of aurones". Current Medicinal Chemistry. 19 (18 ...
... oxidation of superoxide) Cu+-SOD + O2− + 2H+ → Cu2+-SOD + H2O2 (oxidation of copper; reduction of superoxide) The protein ... Frieden, E.; Hsieh, H.S. (1976). Ceruloplasmin: The copper transport protein with essential oxidase activity. Advances in ... Antimicrobial copper alloy products are now being installed in healthcare facilities in the U.K., Ireland, Japan, Korea, France ... Several copper proteins, such as the "blue copper proteins", do not interact directly with substrates; hence they are not ...
Advanced glycation end-products (AGEs) are proteins or lipids that become glycated as the result of a high-sugar diet. They are ... Glyoxal has been observed as a trace gas in the atmosphere, e.g. as an oxidation product of hydrocarbons. Tropospheric ... "Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation" (PDF). Free ... Commercial glyoxal is prepared either by the gas-phase oxidation of ethylene glycol in the presence of a silver or copper ...
Wound care products, such as "Flaminal Hydro" make use of an alginate hydrogel containing glucose oxidase and other components ... GOx is a dimeric protein, the 3D structure of which has been elucidated. The active site where glucose binds is in a deep ... Glucose oxidase catalyzes the oxidation of β-D-glucose into D-glucono-1,5-lactone, which then hydrolyzes into gluconic acid. In ... RSC Advances. 5: 13570-8. doi:10.1039/C4RA16852F. "Detlev Müller discovers glucose oxidase". Tacomed.com. Archived from the ...
After this initial oxidation, the xylenol orange within the assay is also oxidized to produce the product that has the 560 nm ... This is advantageous over other assays in which more advanced oxidation would need to proceed in order to be detected by the ... Modifying the assay can also aid in the detection of protein, as well as lipid, hydroperoxide in human cells. Aside from its ... With the sensing of LOOHs, the FOX reagent only senses the first products of fatty acid oxidation, and is quite useful prior to ...
This rise in metabolic products contributes to generating advanced glycation end-products and oxidative stress along with the ... As for stroke patients, the products from deamination induce cytotoxicity protein cross-linking and amyloid-beta (Aβ) ... Amine oxidases are a family of enzymes that catalyze the oxidation of various endogenous amines, including histamine or ... Additionally, hydrogen peroxide, along with aldehydes and glucose, is involved in generating advanced glycation end-products ...
... and the signatures of specific products caused by particular enzymatic activities. Alpha and beta proteins (α/β) are considered ... The Great Oxidation Event, triggered by the development of phototrophic organisms like cyanobacteria, resulted in a world-wide ... In 1955, Philip Abelson published a short paper that laid out what has become, through several cycles of technical advances, ... Proteins are also more preserved in fossils than DNA, allowing researchers to recover proteins from the enamel of 1.8 million ...
Recent advances have allowed the chains to be synthesized together by inserting the human proinsulin gene into E. coli cells, ... The limiting factor for the use of microorganisms like E. coli in biosynthesis of gene products like insulin is time, yet due ... Joining of the two chains was often carried out through air oxidation with low efficiency. A 1978 study by Goedell et al. ... protein, or other biochemicals from simpler starting materials. The genetic engineering of E. coli with the specific task of ...
The oxidation of a methyl group occurs widely in nature and industry. The oxidation products derived from methyl are CH2OH, CHO ... March, Jerry (1992). Advanced organic chemistry: reactions, mechanisms, and structure. John Wiley & Sons. ISBN 0-471-60180-2. G ... Clarke, Steven G. (2018). "The ribosome: A hot spot for the identification of new types of protein methyltransferases". Journal ... Ultimately oxidation of methyl groups gives protons and carbon dioxide, as seen in combustion. Demethylation (the transfer of ...
"Performic Acid Oxidation of Proteins". Cold Spring Harbor Protocols. 2007: pdb.prot4698. doi:10.1101/pdb.prot4698. Gehr, R; ... Using an excess of either reactant shifts the equilibrium towards the product side. The aqueous product solution can be ... Chen, D; Moreau, M (2009). "Performic acid (PFA): tests on an advanced primary effluent show promising disinfection performance ... The popularity of performic acid as a sterilizer originates from the safe nature of its degradation products, mostly carbon ...
The useful products of methanogenesis are absorbed by the gut, but methane is released from the animal mainly by belching ( ... During advanced stages of organic decay, all electron acceptors become depleted except carbon dioxide. Carbon dioxide is a ... Le Mer, J.; Roger, P. (2001). "Production, oxidation, Emission and Consumption of Methane by Soils: A Review". European Journal ... These organisms may accomplish reverse methanogenesis using a nickel-containing protein similar to methyl-coenzyme M reductase ...
The useful products of methanogenesis are absorbed by the gut, but methane is released from the animal mainly by belching ( ... During advanced stages of organic decay, all electron acceptors become depleted except carbon dioxide. Carbon dioxide is a ... Le Mer, J.; Roger, P. (2001). "Production, oxidation, Emission and Consumption of Methane by Soils: A Review". European Journal ... December 2003). "A conspicuous nickel protein in microbial mats that oxidize methane anaerobically". Nature. 426 (6968): 878-81 ...
In biological context crosslinking could play a role in Atherosclerosis through advanced glycation end-products which have been ... it refers to the use of a probe to link proteins together to check for protein-protein interactions, as well as other creative ... In other cases, when formation of cross-links by oxidation is desirable, an oxidizer such as hydrogen peroxide may be used to ... and a chemical crosslinker could be used to probe the protein-protein interaction between these two proteins by linking them ...
When in the bloodstream, 66% of the substance are bound to plasma proteins. Lorlatinib is able to cross the blood-brain barrier ... Clinical trial number NCT01970865 for "A Study Of PF-06463922 An ALK/ROS1 Inhibitor In Patients With Advanced Non Small Cell ... "Lorviqua: EPAR - Product Information" (PDF). European Medicines Agency. 2019-06-17. "Lorviqua: EPAR - Public assessment report ... Lorlatinib is inactivated by oxidation, mainly through CYP3A4, and by glucuronidation, mainly through UGT1A4. Other CYPs and ...
Matrix metalloproteases (MMPs). Indirect down-regulation of the enzymes MMP 2 and 9. Advanced glycation end product (AGE) ... Protein ADP-ribosylation. Inhibition of protein arginine ADP-ribosylation. ... An alternative pathway, mainly in peripheral tissues, is by diamine oxidase-catalyzed oxidation into agmatine-aldehyde, which ...
... is an advanced non-invasive metabolic screening test distributed by Cordlife Group Limited ("Cordlife"). It can ... the waste product from the kidney) particularly useful for medical diagnostics. The key advantages of using urine as a biofluid ... it being largely free from interfering proteins or lipids. Although the human urine metabolome is a subset of the human serum ... such as sugar metabolism disorders and fatty acid oxidation disorders. Indeed, GC-MS analysis is increasingly becoming a common ...
... and lipid peroxidation products. The encoded protein, known as ADH1B or beta-ADH, can form homodimers and heterodimers with ... Smith M (Mar 1986). "Genetics of human alcohol and aldehyde dehydrogenases". Advances in Human Genetics 15. Advances in Human ... ADH1A and ADH1C subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism (oxidizing ... The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a ...
"Albumin thiol oxidation and serum protein carbonyl formation are progressively enhanced with advancing stages of chronic kidney ... Fu BL, Guo ZJ, Tian JW, Liu ZQ, Cao W (August 2009). "[Advanced glycation end products induce expression of PAI-1 in cultured ... Moreover, the glycation can result in the formation of Advanced Glycation End-Products (AGE), which result in abnormal ... It is the most abundant protein in human blood plasma; it constitutes about half of serum protein. It is produced in the liver ...
Ring A fragment is transferred from the peptidyl carrier protein (PCP) to the acyl carrier protein (ACP) by a keto-synthase (KS ... Advances in Applied Microbiology. 47: 1-32. doi:10.1016/S0065-2164(00)47000-0. ISBN 9780120026470. PMID 12876793. Yu, Victor L ... This intermediate is then modified by oxidation of the primary alcohol to the aldehyde, catalysed by pigM, and methylation ( ... Natural Product Reports. 23 (4): 517-31. doi:10.1039/B605245M. PMID 16874387. Hu, Dennis X.; Withall, David M.; Challis, ...
Genetic Code 2.0 - 3 Synthetic Amino Acids Combined Into One Protein. *Oxidation sets off fatal structural change of human ... 2017). "Xenobiology: State-of-the-art, Ethics and Philosophy of new-to-nature organisms". Advances in Biochemical Engineering/ ... "Expanded genetic code for the engineering of ribosomally synthetized and post-translationally modified peptide natural products ... and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein". Proc. Natl. Acad. Sci. USA ...
For major advances in the understanding of energy transfer and its effect on reaction dynamics. For studies using photo ... Synthesized and characterized site-specifically modified DNA and RNA strands, allowing the study of proteins that interact with ... for remarkable achievements in the area of natural product total synthesis" Jacqueline K. Barton 2006 "For seminal work in the ... chemistry notably the introduction of the kinetic isotope effect as a mechanistic tool in the study of chromate oxidation, the ...
The oxidation state and the coordination number reflect the number of bonds formed between the metal ion and the ligands in the ... An estimated 30% of proteins contain metal ions. Examples include the intensely colored vitamin B12, the heme group in ... Cotton, Frank Albert; Geoffrey Wilkinson; Carlos A. Murillo (1999). Advanced Inorganic Chemistry. p. 1355. ISBN 978-0-471-19957 ... which has silver ion as a product, to shift to the right. This new solubility can be calculated given the values of Kf and Ksp ...
Starch is converted to sugar, which glycates protein, and is oxidized into advanced glycation endproducts (AGEs), a ... Heat-not-burn products heat rather than burn tobacco to generate an aerosol that contains nicotine. Dokha is a middle eastern ... Curing and subsequent aging allow for the slow oxidation and degradation of carotenoids in tobacco leaf. This produces certain ... Cigarettes are a product consumed through inhalation of smoke and manufactured from cured and finely cut tobacco leaves and ...
This protein contains only a mononuclear Fe active site and no iron-sulfur clusters, in contrast to the [FeFe] hydrogenases. [ ... In the case of H2/O2 fuel cells, where the product is water, there is no production of greenhouse gases. EC 1.12.1.2 hydrogen ... The hydrogenation of a methenyl-H4MPT+ occurs instead of H2 oxidation/production, which is the case for the other two types of ... RSC Advances. 3 (22): 8142. doi:10.1039/c3ra22668a. ISSN 2046-2069. Liebgott, P.P.; Leroux, F.; Burlat, B.; Dementin, S.; ...
Among these protein targets, the enzyme N-acyl phosphatidylethanolamine-specific phospholipase D (NAPE-PLD) generates bioactive ... CYP27A1 contributes significantly to total bile acid synthesis by catalyzing sterol side chain oxidation, after which cleavage ... "Rarity of colon cancer in Africans is associated with low animal product consumption, not fiber". Am. J. Gastroenterol. 94 (5 ... "Recent advances in the understanding of bile acid malabsorption". British Medical Bulletin. 92: 79-93. doi:10.1093/bmb/ldp032 ...
In food web terminology, complexity is a product of the number of species and connectance.[70][71][72] Connectance is "the ... Kent, Michael (2000). Advanced Biology. Oxford University Press US. p. 511. ISBN 978-0-19-914195-1.. ... and proteins. These polymers have a dual role as supplies of energy as well as building blocks; the part that functions as ... obtain energy by the chemical oxidation of inorganic compounds and can grow in dark environments, such as the sulfur bacterium ...
Squalene oxidation activates NF-κB (a protein complex) and consequently increases IL-1α levels.[45] Additionally, squalene ... Melnik BC (2011). "Evidence for Acne-Promoting Effects of Milk and Other Insulinotropic Dairy Products". Milk and Milk Products ... Shelley WB, Shelley ED (2001). Advanced Dermatologic Therapy II. W. B. Saunders. ISBN 978-0-7216-8258-7. .. ... protein.[45] PPARα increases the activity of activator protein 1 (AP-1) and NF-κB, thereby leading to the recruitment of ...
1 oxidation state that is characteristic of the other alkali metals and is also the main oxidation state of all the known ... Advances in Inorganic Chemistry and Radiochemistry. 4: 197-229. doi:10.1016/S0065-2792(08)60268-X. ISBN 978-0-12-023604-6. .. ... Francium-223, the only naturally occurring isotope of francium,[58][59] is the product of the alpha decay of actinium-227 and ... The balance between potassium and sodium is maintained by ion transporter proteins in the cell membrane.[231] The cell membrane ...
The elimination half-life is around 2 hours.[8][118] It is moderately bound to plasma proteins, especially albumin.[8] However ... "PRODUCT INFORMATION MOCLOBEMIDE SANDOZ® 150mg and 300mg TABLETS". TGA eBusiness Services. Sandoz. 6 March 2012. Retrieved 16 ... Priest RG, Baldwin DS, Bullock T, Kibel D, Smeyatsky N, Steinert J (June 1992). "Recent advances in antidepressant drugs". S. ... are the N-oxide Ro 12-5637 formed via morpholine N-oxidation and lactam derivative Ro 12-8095 formed via morpholine C-oxidation ...
"Science Advances. 2 (10): e1600492. Bibcode:2016SciA....2E0492D. doi:10.1126/sciadv.1600492. PMC 5061471 . PMID 27757416.. ... Proteins related to the cytoskeleton components of other organisms exist in archaea,[89] and filaments form within their cells, ... However, the archaea that do this, such as Sulfolobus, produce sulfuric acid as a waste product, and the growth of these ... These reactions are particularly important in the oceans.[127][180] The archaea also appear crucial for ammonia oxidation in ...
Organic oxidation Diazonium salt Reagent: nitrous acid Zincke reaction Zincke aldehyde Reagent: pyridinium salts, with primary ... 3) are the most common positively charged moieties in proteins, specifically in the amino acid lysine.[16] The anionic polymer ... Smith, Michael B.; March, Jerry (2007), Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (6th ed.), New York: ... In the case of formaldehyde (R′ = H), these products typically exist as cyclic trimers. ...
... identified a protein that later became known as superoxide dismutase as an indophenol oxidase by protein analysis of starch ... In a series of such reactions, the oxidation state and the charge of the metal cation oscillates between n and n+1: +1 and +2 ... Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage.[2] ... "Recent advances in amyotrophic lateral sclerosis". Current Opinion in Neurology. 13 (4): 397-405. doi:10.1097/00019052- ...
Thus, oxidation is better defined as an increase in oxidation number, and reduction as a decrease in oxidation number. ... Advanced undergraduate-level or graduate text books. *Atkins, P.W. Physical Chemistry (Oxford University Press) ISBN 0-19- ... Reaction mechanisms are proposed to explain the kinetics and the relative product mix of a reaction. Many physical chemists ... Neurochemistry is the study of neurochemicals; including transmitters, peptides, proteins, lipids, sugars, and nucleic acids; ...
Bader N, Grune T (2006). "Protein oxidation and proteolysis". Biological Chemistry. 387 (10-11): 1351-5. doi:10.1515/BC. ... These peptides are products of proteasomal degradation of proteins originated by the invading pathogen. Although constitutively ... "Bortezomib with chemotherapy is highly active in advanced B-precursor acute lymphoblastic leukemia: Therapeutic Advances in ... The protein degradation processEdit. Ribbon diagram of ubiquitin, the highly conserved protein that serves as a molecular tag ...
In advanced scurvy there are open, suppurating wounds and loss of teeth and, eventually, death. The human body can store only a ... Dewick, P. M. (2009). Medicinal Natural Products: A Biosynthetic Approach (3rd ed.). John Wiley and Sons. p. 493. ISBN 978- ... Ascorbic acid and some of its salts and esters are common additives added to various foods, mostly to retard oxidation. The ... Savini I, Rossi A, Pierro C, Avigliano L, Catani MV (April 2008). "SVCT1 and SVCT2: key proteins for vitamin C uptake". Amino ...
Any segment of DNA that contains the information necessary to produce a functional RNA and/or protein product in a controlled ... A series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetyl-CoA derived ... and advanced and substantiated with microbiological evidence by Lynn Margulis in 1967.. endotherm. An organism that is capable ... G protein. A family of proteins that act as molecular switches inside cells, and are implicated in transmitting signals from a ...
9: Riboflavin". Advanced Nutrition and Human Metabolism (5th ed.). Wadsworth: CENGAG Learning. pp. 329-33.. ... Oxidation of pyruvate, α-ketoglutarate, and branched-chain amino acids requires FAD in the shared E3 portion of their ... In whole milk, 14% of the flavins are bound noncovalently to specific proteins.[15] Egg white and egg yolk contain specialized ... Riboflavin is added to baby foods, breakfast cereals, pastas and vitamin-enriched meal replacement products. It is difficult to ...
"Advances in Nutrition (Bethesda, Md.)》 6 (4): 430-439. doi:10.3945/an.114.008177. ISSN 2156-5376. PMC 4496738. PMID 26178027.. ... Dills, WL (1993). "Protein fructosylation: Fructose and the Maillard reaction". 》Journal of Clinical Nutrition》 58: 779-787.. ... EFSA Panel on Dietetic Products, Nutrition and Allergies (2011). "Scientific Opinion on the substantiation of health claims ... McGrane, MM (2006). 》Carbohydrate metabolism: Synthesis and oxidation》. Missouri: Saunders, Elsevier. 258-277쪽. ISBN 1-4160- ...
... compounds can undergo oxidation and coupling reaction as shown in the scheme below to form high molecular weight products, ... Skin and fingernails are made of a similar type of keratinized protein as hair. That means that drips, slips and extra hair ... Alexander Chan, Sean Kung, (September, 2006), "Hair Colorant Technology Advances Further", Personal Care, p. 11-16 ... "Household Products Database - Health and Safety Information on Household Products". hpd.nlm.nih.gov. Retrieved 2017-02-12.. ...
Each subunit is composed of a protein chain tightly associated with a non-protein prosthetic heme group. Each protein chain ... Iron's oxidation state in oxyhemoglobin[edit]. Assigning oxygenated hemoglobin's oxidation state is difficult because ... Hb A1c is the product of the irreversible reaction of hemoglobin A with glucose. A higher glucose concentration results in more ... "An unexpected inverse relationship between HbA1c levels and mortality in patients with diabetes and advanced systolic heart ...
Folic acid is added to grain products in more than 80 countries,[10] and these fortified products make up a significant source ... "Advances in Nutrition. 8 (1): 27-39. doi:10.3945/an.116.013516. PMC 5227980. PMID 28096125. Archived from the original on 8 ... RNA transcription and subsequent protein synthesis are less affected by folate deficiency, as the mRNA can be recycled and used ... It results from oxidation of methylene-THF. It also forms from formate donating formyl group to THF. ...
5-lipoxygenase-activating protein), metabolize the initial product of ALOX5, 5S-HpETE, to LTB4 (i.e. Leukotriene-A4 hydrolase ... Advances in Experimental Medicine and Biology. 507: 117-21. doi:10.1007/978-1-4615-0193-0_19. ISBN 978-0-306-47283-1. . PMID ... oxidation-reduction process. • lipoxygenase pathway. • neutrophil degranulation. • cytokine-mediated signaling pathway. • ... ALOX5 binds with the F actin-binding protein, coactin-like protein. Based on in vitro studies, this protein binding serves to ...
... , a multi-purpose product of Mycenaean Greece (c. 1600-1100 BC) at that time, was a chief export.[12] Olive tree ... health claims on olive oil were approved for protection by its polyphenols against oxidation of blood lipids,[112] and for the ... "Recovering bioactive compounds from olive oil filter cake by advanced extraction techniques". Int J Mol Sci. 15 (9): 16270-83 ... Protein: 0. *Vitamin E: 1.9 mg (10% of DV). *Vitamin K: 8.1 µg (10% of DV) ...
Bioavailability = 80-100%; protein binding = 90-99%; hepatic metabolism, mostly via CYP2C9 and CYP2C19-mediated oxidation; ... Where † indicates products that are no longer marketed. Etymology[edit]. The word analgesic derives from Greek an- (ἀν-, " ... "Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations". Arch. Neurol. 60 (11): 1524-34. doi: ... Protein binding , 99%; half-life = 2-4 hours; hepatically metabolised via oxidation, hydroxylation, dehalogenation and ...
protein oxidation. • triglyceride-rich lipoprotein particle remodeling. • response to drug. • triglyceride metabolic process. • ... advances in the study of an enigmatic protein". Journal of Lipid Research. 42 (11): 1727-39. PMID 11714842.. ... Processing of primary translation products". Hoppe-Seyler's Zeitschrift für Physiologische Chemie. 364 (3): 227-37. doi:10.1515 ... cellular protein metabolic process. • transport. • positive regulation of phagocytosis. • protein stabilization. Sources:Amigo ...
Ethylene is perceived by a family of five transmembrane protein dimers such as the ETR1 protein in Arabidopsis. The genes ... Oxidation. Ethylene is oxidized to produce ethylene oxide, a key raw material in the production of surfactants and detergents ... Lin, Z.; Zhong, S.; Grierson, D. (2009). "Recent advances in ethylene research". J. Exp. Bot. 60 (12): 3311-36. doi:10.1093/jxb ... Products of these intermediates include polystyrene, unsaturated polyesters and ethylene-propylene terpolymers.[13] ...
Jae-Hwan, Lee; Eun-Kyeong, Shin; Dongoh, Lee; Eui-Bae, Jeung (April 2015). "SAT-532: Expression of Beta-Oxidation Related Genes ... a protein in red blood cells. The binding capacity of hemoglobin is influenced by the partial pressure of oxygen in the ... Advanced SEAL Delivery System. *Cosmos CE2F series. *Dry Combat Submersible. *Human torpedo ...
Other products producedEdit. The main products of malolactic fermentation are lactic acid, diacetyl, acetic acid, acetoin, and ... due to the resulting change in pH which affects the solubility of proteins in wine. For this reason, protein fining and heat ... Before the introduction of complex nutritional supplements and advances in freeze-dried cultures of LAB, winemakers would ... The exact compound behind this is derivatives of the amino acid lysine created through an oxidation reaction with ethanol.[7] ...
Dietary sources of protein include both animals and plants: meats, dairy products, fish and eggs, as well as grains, legumes ... The overall protein requirement increases because of amino acid oxidation in endurance-trained athletes.[32] Endurance athletes ... Gropper SS, Smith JL, Groff JL (2009). Advanced nutrition and human metabolism. Belmont, CA: Wadsworth Cengage Learning. ISBN 0 ... This article is about protein as nutrient. For protein as class of molecule, see protein. For other uses, see bodybuilding ...
Sohal RS (July 2002). "Role of oxidative stress and protein oxidation in the aging process". Free Radical Biology & Medicine. ... German JB (1999). "Food Processing and Lipid Oxidation". Impact of Processing on Food Safety. Advances in Experimental Medicine ... are especially susceptible to oxidation and ozonolysis. They can be protected by antiozonants. Solid polymer products start to ... The thioredoxin system contains the 12-kDa protein thioredoxin and its companion thioredoxin reductase.[149] Proteins related ...
a b c U.S. Consumer Product Safety Commission, Carbon Monoxide Questions and Answers Archived 2010-01-09 at the Wayback Machine ... The oxidation state of carbon in carbon monoxide is +2 in each of these structures. It is calculated by counting all the ... CooA is a carbon monoxide sensor protein.[45] The scope of its biological role is still unknown; it may be part of a signaling ... advanced materials and technology". Chem. Soc. Rev. 46 (5): 1427-1463. doi:10.1039/C6CS00403B.. ...
Starch is converted to sugar, which glycates protein, and is oxidized into advanced glycation endproducts (AGEs), a ... Allan Brandt, The Cigarette Century: The Rise, Fall, and Deadly Persistence of the Product That Defined America (2007) ... Curing and subsequent aging allow for the slow oxidation and degradation of carotenoids in tobacco leaf. This produces certain ... The Cigarette Century: The Rise, Fall, and Deadly Persistence of the Product That Defined America (2007) ...
In such proteins, the pigments are arranged to work together. Such a combination of proteins is also called a light-harvesting ... The oxidation of water is catalyzed in photosystem II by a redox-active structure that contains four manganese ions and a ... This product is also referred to as 3-phosphoglyceraldehyde (PGAL) or, more generically, as triose phosphate. Most (5 out of 6 ... In depth, advanced treatment of photosynthesis, also from Govindjee. *Science Aid: Photosynthesis Article appropriate for high ...
Food productsEdit. Naturally-occurring melatonin has been reported in foods including tart cherries to about 0.17-13.46 ng/g,[ ... "Melatonin receptors , G protein-coupled receptors , IUPHAR/BPS Guide to Pharmacology". www.guidetopharmacology.org. Retrieved 7 ... Hardeland R (February 2015). "Melatonin in plants and other phototrophs: advances and gaps concerning the diversity of ... new aspects of the oxidation chemistry of this indole accessed in vitro". Ann. N. Y. Acad. Sci. 738 (1): 419-20. Bibcode: ...
Advanced oxidation protein products (AOPP) are reportedly elevated in the plasma of patients with a number of diseases, ... M. Kalousová, J. Škrha, and T. Zima, "Advanced glycation end-products and advanced oxidation protein products in patients with ... "Advanced oxidation protein products induce monocyte chemoattractant protein-1 expression via p38 mitogen-activated protein ... Advanced oxidation protein products (AOPP) are reportedly elevated in the plasma of patients with a number of diseases, ...
Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK/NF-κB- ... To determine whether advanced oxidation protein products (AOPPs) can induce the expression of chemokine monocyte ... Pretreatment with SLs inhibited MCP-1 mRNA and protein expression and suppressed IKKβ and NF-κB p65 phosphorylation and IκBα ... MCP-1 mRNA and protein expression were tested using quantitative real-time PCR and ELISA, respectively, and the protein levels ...
Plasma levels of advanced oxidation protein products (AOPP) and adiponectin were measured before and 3 months after candesartan ... Impact of angiotensin II receptor blocker on plasma levels of adiponectin and advanced oxidation protein products in peritoneal ... Blood Proteins / analysis*. Female. Humans. Kidney Failure, Chronic / blood*, complications, therapy*. Male. Middle Aged. ... Oxidation-Reduction / drug effects. Oxidative Stress / drug effects*. Peritoneal Dialysis*. Tetrazoles / administration & ...
At 1 hour post-intake, serum values for 8-iso-PGF2-alpha and advanced oxidation protein products decreased significantly by 40 ... Additionally, there was a trend toward decreased C-reactive protein, and increased nitric oxide levels. Both placebo and PRB ... such as those related to oxidation and inflammation, can be an advantageous strategy for early clinical research on an ... ingredient or product. 31 total healthy subjects were randomized in a double-blinded, placebo-controlled, acute pilot study ...
... are uremic toxins created during oxidative stress through the reaction of plasma proteins with chlorinated oxidants such as ... Product Details Advanced Oxidation Protein Products (AOPP) are uremic toxins created during oxidative stress through the ... 2019). Advanced Oxidation Protein Products and Carbonylated Proteins Levels in Endovascular and Open Repair of an Abdominal ... 2014). Advanced oxidation protein products induce intestine epithelial cell death through a redox-dependent, c-jun N-terminal ...
Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int. 1996;49:1304-13.CrossRefPubMed ... Advanced protein oxidation products (APOP) assay:. APOP levels were measured by a modification of the method of Witko-Sarsat et ... APOP-Advanced protein oxidation product expressed as nmol/mL equivalent to Chloramine-T ... ROOH and helps against protein oxidation [41]. Our study revealed that administration of oral CCl4 reduced the amount of anti- ...
Advanced Oxidation Protein Products. Advanced oxidation protein products (AOPPs) are plasma compounds preferentially formed ... Increased level of advanced oxidation protein products in patients with coronary artery disease. Atherosclerosis 2002;162:221- ... Concentration of total (free + protein bound) plasma nitrotyrosine, as an end product of protein nitration by peroxynitrite ( ... Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats. J Clin Invest 1996;97:238-243 ...
Advanced Oxidation Protein Products. Advanced oxidation protein products (AOPPs) are plasma compounds preferentially formed ... Increased level of advanced oxidation protein products in patients with coronary artery disease. Atherosclerosis 2002;162:221- ... Concentration of total (free + protein bound) plasma nitrotyrosine, as an end product of protein nitration by peroxynitrite ( ... Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats. J Clin Invest 1996;97:238-243 ...
... and antioxidant protein expression by Western blotting and antioxidant enzyme activity in the heart were evaluated. The MI ... and antioxidant protein expression by Western blotting and antioxidant enzyme activity in the heart were evaluated. The MI ... Moreover, histological analyses of the heart (collagen and hypertrophy), cardiac oxidative stress (advanced oxidation protein ... Moreover, histological analyses of the heart (collagen and hypertrophy), cardiac oxidative stress (advanced oxidation protein ...
Keywords: Advanced oxidation protein products, Biomarkers, Clinical studies, Oxidative stress, Myeloperoxidase, Inflammation, ... Keywords:Advanced oxidation protein products, Biomarkers, Clinical studies, Oxidative stress, Myeloperoxidase, Inflammation, ... Title:Circulating Advanced Oxidation Protein Products as Oxidative Stress Biomarkers and Progression Mediators in Pathological ... Circulating Advanced Oxidation Protein Products as Oxidative Stress Biomarkers and Progression Mediators in Pathological ...
Assay of advanced oxidation protein products in sera. Advanced oxidation protein products (AOPP) were assayed by ... Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int 1996; 49: 1304-1313. ... Serum advanced oxidation protein products (AOPP), MPO-induced hypochlorous acid (HOCl) and serum-induced fibroblast ... Hypochlorous acid (HOCl) and advanced oxidation protein products (AOPP) modulate fibroblast proliferation in vitro. NIH 3T3 ...
A) Advanced Oxidation Protein Product (AOPP) concentrations in sera from HOCl-mice and HOCl-mice treated with 2.5 × 105 WT-, or ... Determination of Advanced Oxidation Protein Product (AOPP) Concentrations in Sera. AOPP concentration was measured by ... Radical oxygen species production induced by advanced oxidation protein products predicts clinical evolution and response to ... Selective oxidation of DNA topoisomerase 1 induces systemic sclerosis in the mouse. J Immunol. (2009) 182:5855-64. doi: 10.4049 ...
... β-carotene versus changes of the serum concentration of advanced oxidation protein products (∆AOPP), changes of serum ... Keywords: malondialdehyde; advanced oxidation protein products; 8oxodG; ceruloplasmin; glutathione peroxidase; lactate ... advanced oxidation protein products; 8oxodG; ceruloplasmin; glutathione peroxidase; lactate dehydrogenase; interleukin 6; β- ... β-carotene versus changes of the serum concentration of advanced oxidation protein products (∆AOPP), changes of serum ...
Advanced Oxidation Protein Products and the CLOCK 3111T/C Single Nucleotide Polymorphism in Menopausal Women with Insomnia. ... Background: The aim of this study was to assess the dependence of advanced oxidation protein products (AOPPs) levels on the ... The study of the CLOCK 3111T/C SNP (rs1801260) was performed by PCR. The blood level of advanced oxidation protein products ( ... Home » Advanced Oxidation Protein Products and the CLOCK 3111T/C Single Nucleotide Polymorphism in Menopausal Women with ...
Objective To observe the effect of advanced oxidation protein products (AOPPs) on articular and synovial in a rabbit model of ... The effect of advanced oxidation protein products on articular cartilage and synovial membrane in a rabbit model of ... The effect of advanced oxidation protein products on articular cartilage and synovial memb ... the protein expression level of matrix metalloproteinases (MMP)-3 on synovial at 4 and 8 weeks in AOPPs group were 1.006±0.080, ...
Superoxide dismutase (SOD), advanced oxidation protein products (AOPP), and disease-modifying treatment are related to better ... Superoxide dismutase (SOD), advanced oxidation protein products (AOPP), and disease-modifying treatment are related to better ... advanced oxidation protein products (AOPP) superoxide dismutase (SOD), catalase (CAT), uric acid, bilirubin, albumin, and ...
INTRODUCTION AND AIMS: Serum advanced oxidation protein products (AOPP) are new markers of protein damage induced by oxidative ... INTRODUCTION AND AIMS: Serum advanced oxidation protein products (AOPP) are new markers of protein damage induced by oxidative ... OXIDATIVE STRESS IN CHRONIC RENAL FAILURE AND HYPERTESION: ROLE OF ADVANCED OXIDATION PROTEIN PRODUCTS (AOPP). ... OXIDATIVE STRESS IN CHRONIC RENAL FAILURE AND HYPERTESION: ROLE OF ADVANCED OXIDATION PROTEIN PRODUCTS (AOPP) ...
Advanced Oxidation Protein Products , Cross-Sectional Studies , Fertilization in Vitro , Humans , Male , Semen , Spermatozoa , ... Association of advanced oxidation protein products in seminal plasma with teratospermia and outcome parameters of fertilization ... [email protected]#To study the association of the level of advanced oxidation protein products (AOPPs) in seminal plasma with ... Association of advanced oxidation protein products in seminal plasma with teratospermia an ...
Superoxide dismutase (SOD), advanced oxidation protein products (AOPP), and disease-modifying treatment are related to better ... advanced oxidation protein products (AOPP), and disease-modifying treatment are related to better relapse recovery after ... advanced oxidation protein products (AOPP), and disease-modifying treatment are related to better relapse recovery after ... advanced oxidation protein products (AOPP), and disease-modifying treatment are related to better relapse recovery after ...
... and advanced oxidation protein products (AOPP) arise as a result of excessive glycation and oxidation processes of proteins in ... Kalousová M, Krha J, Zima T. Advanced glycation end-products and advanced oxidation protein products in patients with diabetes ... and advanced oxidation protein products (AOPP) arise as a result of excessive glycation and oxidation processes of proteins in ... The results of these processes are advanced glycation endproducts and advanced oxidation protein products. Nonenzymatic ...
Advanced oxidation protein products (AOPPs) are specific markers of protein oxidation. Objective: To explore the role of AOPPs ... Results: 1. Advanced oxidation protein products in different subgroups of HSP patients are all higher than the controls, while ... Serum level of advanced oxidation protein products (AOPPs) in patients with Henoch-Schonlein purpura and its relationship with ... Conclusion: Advanced oxidation protein products play an important role in the pathogenesis of HSP, especially in renal-type ...
Reactive aldehydes derived from reducing sugars and peroxidation of lipids covalently modify proteins and may contribute to ... a mechanism for producing advanced glycation end products at sites of inflammation J Clin Invest. 1999 Jul;104(1):103-13. doi: ... Oxidation-Reduction * Peroxidase / metabolism* * Protein Processing, Post-Translational* * Ribonuclease, Pancreatic / drug ... exposed to free L-serine and HOCl exhibits the biochemical hallmarks of advanced glycation end (AGE) products -- browning, ...
Captopril Restores Endothelium-Dependent Relaxation Induced by Advanced Oxidation Protein Products in Rat Aorta. Chen, ... Divergent Action of Calcium Channel Blockers on ATP-Binding Cassette Protein Expression. Hasegawa, Kazuhiro; Wakino, Shu; Kanda ...
... advanced oxidation protein products; IL-6, interleukin-6. Gy, gray unit; LDH, lactate dehydrogenase; ALT, alanine ... Providing rats beetroot juice (8 mL∙kg∙bm∙day−1) for 28 days was shown to attenuate lipid peroxidation, protein oxidation and ... protein and lipid structures susceptible to oxidation and functional impairments [45,46,47]. ... NF-κB, nuclear factor kappa B; NP-SH, non-protein sulfhydryl; DMBA, 7,12-dimethylbenz[a]anthracene; NQO1, NAD(P)H dehydrogenase ...
Oxidation-reduction reaction Oxidation-reduction reactions Soy protein Health aspects Usage Soybean products Superoxide ... An evaluation of heat on protein oxidation of soy protein isolate or soy protein isolate mixed with soybean oil in vitro and ... protein carbonyl and advanced oxidation protein products (AOPPs) content. The content of MDA was determined by following the ... protein+isolate+or...-a0502652718. *APA style: An evaluation of heat on protein oxidation of soy protein isolate or soy protein ...
Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK-NF-κB- ... Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK-NF-κB- ... Sesquiterpene Lactones Inhibit Advanced Oxidation Protein Product-Induced MCP-1 Expression in Podocytes via an IKK-NF-κB- ... To determine whether advanced oxidation protein products AOPPs can induce the expression of chemokine monocyte chemoattractant ...
Paeonol attenuates advanced oxidation protein product-induced oxidative stress injury in THP-1 macrophages.Dec 31, 2013. ... Diseases : Cholesterol: Oxidation, Lipid Peroxidation. Pharmacological Actions : Anti-Apoptotic, Bcl-2 protein down-regulation ... This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members ... Diseases : Atherosclerosis, C-Reactive Protein, High Fat Diet. Pharmacological Actions : Anti-Inflammatory Agents, Interleukin- ...
... reduced the expression of NOX and inhibited the inflammatory response caused by Advanced oxidation protein products in ... This section is for allowing more advanced sorting methods. Currently, these advanced sorting methods are available for members ... Propolis reduces the expression of autophagy-related proteins in chondrocytes under interleukin-1β stimulus.Jul 31, 2019. ...
advanced oxidation protein product; ARB, angiotensin type 1 receptor blocker; ASMC, aortic smooth muscle cell; CKD, chronic ... nucleotide-binding oligomerization domain-containing protein 2; NOX, NADPH oxidase; PFD, pirfenidone; PKC, protein kinase C; ... monocyte chemoattractant protein-1; mtROS, mitochondrial ROS; NF-κB, nuclear factor kappa-light-chain-enhancer of activated B ...
Levels of renalase and advanced oxidation protein products with regard to catecholamines in haemodialysed patients. Marcin ... Benefits and risks associated with genetically modified food products Biological psychological and social determinants of old ...
  • Advanced oxidation protein products (AOPP) are reportedly elevated in the plasma of patients with a number of diseases, including diabetes mellitus, that involve oxidative stress. (hindawi.com)
  • The advanced oxidation protein products (AOPP) assay is a widely published method to determine plasma oxidative stress, based on a spectrophotometric assay in a 96-well microplate format [ 2 ]. (hindawi.com)
  • Plasma levels of advanced oxidation protein products (AOPP) and adiponectin were measured before and 3 months after candesartan administration, and 3 months after discontinuation. (biomedsearch.com)
  • Advanced Oxidation Protein Products ( AOPP ) are uremic toxins created during oxidative stress through the reaction of plasma proteins with chlorinated oxidants such as chloramines or hypochlorous acid. (cellbiolabs.com)
  • Serum advanced oxidation protein products (AOPP), MPO-induced hypochlorous acid (HOCl) and serum-induced fibroblast proliferation were assayed. (ersjournals.com)
  • We analyzed in plasma/serum the following: pro-oxidative-antioxidative balance (PAB), nitrates and nitrites (NO3 + NO2), malondialdehyde (MDA), advanced oxidation protein products (AOPP) superoxide dismutase (SOD), catalase (CAT), uric acid, bilirubin, albumin, and transferrin in all patients and additionally after corticosteroid relapse treatment. (ac.rs)
  • INTRODUCTION AND AIMS: Serum advanced oxidation protein products (AOPP) are new markers of protein damage induced by oxidative stress. (unime.it)
  • Determination of advanced AOPP was based on spectrophotometric method detection. (unime.it)
  • Advanced glycation endproducts (AGE) and advanced oxidation protein products (AOPP) arise as a result of excessive glycation and oxidation processes of proteins in hyperglycemia and oxidative stress conditions respectively, both in vivo and in vitro. (biomedcentral.com)
  • Similarly, as a result of multi-stage transformations of proteins induced by oxygen and chlorine free radicals, advanced oxidation protein products (AOPP) are formed. (biomedcentral.com)
  • Advanced oxidation protein products (AOPP) are newly identified efficient oxidative stress biomarkers. (nih.gov)
  • Plasma advanced oxidation protein products (AOPP) and % hemolysis were estimated as protein oxidation indicators. (alliedacademies.org)
  • Recent studies indicate that increased production of reactive oxygen species (ROS) can promote development of malignancy .Over production of ROS within the tissue can damage DNA, proteins, lipids and carbohydrates [ 1 , 2 ], producing oxidized products like advanced oxidation protein products (AOPP), malondialdehyde (MDA),advanced glycation end products etc [ 3 ]. (alliedacademies.org)
  • To determine protein oxidation AOPP and % hemolysis were estimated. (alliedacademies.org)
  • In addition, twenty-six sera from HCC patients treated by sorafenib were analyzed for serum levels of advanced oxidation protein products (AOPP). (aacrjournals.org)
  • The measurement of AOPP is proposed to be a reliable marker to estimate the degree of oxidant-mediated protein damage in uremic patients and to predict the potential efficacy of therapeutic strategies aimed at reducing such an oxidative stress. (immundiagnostik.com)
  • advanced oxidation protein products (AOPP) and protein carbonyl (PC), were measured in blood samples collected at week 0, before any interventions took place. (uib.no)
  • Blood samples were also collected at these times and analyzed for TAG, malondialdehyde (MDA), hydrogen peroxide (H 2 O 2 ), advanced oxidation protein products (AOPP), nitrate/nitrite (NOx), and Trolox Equivalent Antioxidant Capacity (TEAC). (pubmedcentralcanada.ca)
  • To determine whether advanced oxidation protein products (AOPPs) can induce the expression of chemokine monocyte chemoattractant protein- (MCP-) 1 in cultured mouse podocytes and to explore the mechanisms of the potential renoprotection of SLs, we treated podocytes with AOPPs and SLs (parthenolide and its derivatives micheliolide, compound 1, and compound 2). (hindawi.com)
  • AOPPs activated the expression of MCP-1 mRNA and protein in a dose- and time-dependent manner, activated IKK β and NF- κ B p65, and promoted I κ B α degradation. (hindawi.com)
  • Moreover, histological analyses of the heart (collagen and hypertrophy), cardiac oxidative stress [advanced oxidation protein products (AOPPs)], pro- and antioxidant protein expression by Western blotting and antioxidant enzyme activity in the heart were evaluated. (frontiersin.org)
  • New compounds, which can be used as biomarkers, have been identified, and among them advanced oxidation protein products (AOPPs), formed mainly by chlorinated oxidants resulting from activity of myeloperoxidase. (eurekaselect.com)
  • The aim of this study was to assess the dependence of advanced oxidation protein products (AOPPs) levels on the genotype of the CLOCK 3111T/C SNP in Caucasian menopausal women with and without insomnia. (ijbm.org)
  • The blood level of advanced oxidation protein products (AOPPs) was detected by IEMA. (ijbm.org)
  • Objective To observe the effect of advanced oxidation protein products ( AOPPs ) on articular and synovial in a rabbit model of osteoarthritis (OA). (bvsalud.org)
  • Design, setting, participants, & measurements Sera from 292 patients and 69 healthy controls from Italy and the United States were assayed for advanced oxidation protein products (AOPPs), free sulfhydryl groups on albumin (SH-Alb), and IgA1 with galactose-deficient hinge-region O -glycans (Gd-IgA1). (asnjournals.org)
  • Moreover, increased serum levels of another marker of oxidative stress, advanced oxidation protein products (AOPPs), have been recently associated with proteinuria and disease progression in patients with IgAN ( 12 ). (asnjournals.org)
  • serum levels of markers of oxidative stress, i.e. , advanced oxidation protein products ([C] AOPPs) and albumin containing free SH groups ([D] SH-Alb) in 69 healthy controls and in 292 patients with IgAN. (asnjournals.org)
  • Correlation between proteinuria at sampling (g/d) and serum levels of AOPPs (A) or serum Gal-deficient IgA1 expressed as percentage of a standard Gal-deficient IgA1 (Ale) myeloma protein ([B] %HAA) in 62 patients with IgAN. (asnjournals.org)
  • Markers of protein oxidation are named as advanced oxidation protein products (AOPPs) which have been. (academicjournals.org)
  • Advanced glycation end products (AGEs), advanced oxidation protein products (AOPPs), and nitrosylated proteins (NPs) can be used as markers of oxidative stress and inflammation. (ingentaconnect.com)
  • Nonenzymatic glycation and oxidation concerns proteins, lipids and nucleic acids, which cause a series of adverse changes in their structure and function. (biomedcentral.com)
  • Reactive aldehydes derived from reducing sugars and peroxidation of lipids covalently modify proteins and may contribute to oxidative tissue damage. (nih.gov)
  • AGEs accumulate on nucleic acids, proteins, and lipids. (townsendletter.com)
  • OS has deleterious effect on cell structures as lipids, proteins and DNA. (academicjournals.org)
  • Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars. (wikipedia.org)
  • SCXK (Yue) 2006-0015) weighing reactive oxygen species (ROS) and limited antioxidant 180-220 g were housed in a room at a constant capacity can lead to severe damage on cellular compo- temperature with a 12-h light-12-h dark cycle and were nents such as DNA, proteins, nucleic acids, and lipids in given free access to food and water. (deepdyve.com)
  • The in vivo oxidation of lipids and lipid-containing molecules has been discovered to be initiated by the concurrent reaction of such lipid materials with reducing sugars such as glucose, advanced glycosylation endproducts such as AGE-peptides, or a compound which forms advanced glycosylation endproducts, to form materials or particles known as AGE-lipids. (freepatentsonline.com)
  • Elevated glycemia accelerates the formation of advanced glycation end products (AGEs), which generate reactive oxygen species (ROS) and promote inflammation ( 2 ). (diabetesjournals.org)
  • It is a step in the formation of advanced glycation end products (AGEs). (townsendletter.com)
  • Later- or advanced-stage glycation processes involving degradation of FL and glycation of proteins by MG and related physiological dicarbonyl metabolites form advanced glycation end products (AGEs) ( 1 ). (diabetesjournals.org)
  • Liquid chromatography-tandem mass spectrometry also revealed two major forms of each AGE: AGE moieties of proteins, called AGE residues by conventional biochemical nomenclature (also known by the trivial nomenclature of "protein-bound AGEs"), and AGE free adducts (glycated amino acids) formed mainly by the proteolysis of AGE-modified proteins. (diabetesjournals.org)
  • Protein AGE residues have low renal clearance and biodistribution limited to that of the protein on which they are formed, whereas free adducts have high renal clearance and membrane permeability via amino acid and other transporters and are the major form in which AGEs are cleared from the body by urinary excretion ( 2 ). (diabetesjournals.org)
  • The low-glycemic diet minimized the accumulation of AGEs as well as the oxidation of long-chain polyunsaturated fats. (worldhealth.net)
  • Fructose is 10 times more likely than glucose to cross-link with a protein in the body, forming what are known as advanced glycation end products (AGEs) 2 . (bodyecology.com)
  • As we mentioned before, AGEs develop from the cross-linking of sugars in the blood with proteins. (bodyecology.com)
  • Collagen is one of the most abundant proteins in our body, and its susceptibility to AGEs is one reason why the hardening and stiffening of internal vascular walls becomes such a problem in those with high-sugar diets. (bodyecology.com)
  • Advanced glycation end products (AGEs) are important mediators of diabetic nephropathy that act through the receptor for AGEs (RAGE), as well as other mechanisms, to promote renal inflammation and glomerulosclerosis. (diabetesjournals.org)
  • Prolonged hyperglycemia, dyslipidemia, and oxidative stress in diabetes result in the accumulation of advanced glycation end products (AGEs), which contribute to the development and progression of renal damage ( 1 , 2 ) as well as other diabetes complications ( 3 ). (diabetesjournals.org)
  • AGEs can also cause glycation of LDL which can promote its oxidation. (wikipedia.org)
  • Finally, AGEs can bind to RAGE (receptor for advanced glycation end products) and cause oxidative stress as well as activation of inflammatory pathways in vascular endothelial cells. (wikipedia.org)
  • citation needed] In clearance, or the rate at which a substance is removed or cleared from the body, it has been found that the cellular proteolysis of AGEs-the breakdown of proteins-produces AGE peptides and "AGE free adducts" (AGE adducts bound to single amino acids). (wikipedia.org)
  • AIMS To localise advanced glycation end products (AGEs) in human optic nerve head. (bmj.com)
  • Recently, advanced glycation end products (AGEs) have been revealed to have an important role in age related changes and diabetic complications in several organs. (bmj.com)
  • Glycation occurs when proteins react with sugars and form advanced glycation end products (AGEs). (smart-publications.com)
  • The biomarkers included advanced glycation end products (AGEs) that are formed when sugar metabolites react with proteins. (tufts.edu)
  • The pathways leading to several advanced glycation end products (AGEs) such as (carboxymethyl)lysine, pentosidine, and glucosepane are outlined, whereas other AGEs useful as potential biomarkers of glycation are only briefly mentioned. (nih.gov)
  • Background - The products of nonenzymatic glycation and oxidation of proteins, the advanced glycation end products (AGEs), form under diverse circumstances such as aging, diabetes, and kidney failure. (ahajournals.org)
  • Recent studies suggested that AGEs may form in inflamed foci, driven by oxidation or the myeloperoxidase pathway. (ahajournals.org)
  • The receptor for advanced glycation end products has multiple ligands including advanced glycation end products (AGEs) and proinflammatory ligands, which are formed at an accelerated rate in diabetes due to hyperglycaemia and increased oxidant stress. (wiley.com)
  • Of the several blood and urine tests that the scientists developed, the most accurate one found that children with ASD had higher levels of a compound called dityrosine and another class of compounds called advanced glycation end-products (AGEs). (medicalnewstoday.com)
  • Dityrosine is a marker of oxidation damage, and AGEs are the result of glycation, which is a process wherein sugars combine with amino acids, the "building blocks of proteins. (medicalnewstoday.com)
  • Mariateresa Cristani, Antonio Speciale, Antonella Saija, Sebastiano Gangemi, Paola Lucia Minciullo and Francesco Cimino, "Circulating Advanced Oxidation Protein Products as Oxidative Stress Biomarkers and Progression Mediators in Pathological Conditions Related to Inflammation and Immune Dysregulation", Current Medicinal Chemistry (2016) 23: 3862. (eurekaselect.com)
  • At 1 hour post-intake, serum values for 8-iso-PGF2-alpha and advanced oxidation protein products decreased significantly by 40% and 39%, respectively. (biomedcentral.com)
  • Administration of CCl 4 increased the serum ALT, AST, ALP enzymatic activities and lipid peroxidation products but decreased the cellular antioxidant activities and reduced glutathione (GSH) levels in rats which were brought back to near normal levels by the treatment with Citrus macroptera . (springer.com)
  • Induction of the neutrophil oxidative burst via Fcγ receptor cross-linking was accompanied by up-regulation of neutrophil surface CD11b, CD35, and CD66b only in the presence of selected serum proteins, such as purified human C4, C5, or human serum albumin (HSA). (jimmunol.org)
  • In conclusion, we demonstrate that neutrophil-derived ROI modify selected serum proteins, which, in turn, act as proinflammatory mediators of neutrophil stimulation. (jimmunol.org)
  • Erythrocyte sedimentation rate, leucocytes counts, serum C-reactive protein, neutrophil, and serum lipid peroxidation and intracellular Ca2+ release levels were higher in active and inactive groups than in the control group, although their levels were lower in active group than in inactive group. (deepdyve.com)
  • We identified a significant increase in the amount of acute phase protein serum amyloid A1, albumin, lipoprotein-associated phospholipase A2, and apoC-III composing uremic HDL. (asnjournals.org)
  • The multi-stage conversion, initiated by a glucose connection to free amino groups of proteins, leading to the creation of glycation products, is commonly known as the Maillard reaction. (biomedcentral.com)
  • Diabetes is associated with increased glycation of proteins by glucose and methylglyoxal (MG). Early-stage glycation by glucose forms fructosamine adducts, mainly N ε -fructosyl-lysine (FL), which can be exploited for assessment of glycemic control in the measurement of A1C (FL and N α -fructosyl-valine). (diabetesjournals.org)
  • In patients with type 1 diabetes (T1DM), however, we found plasma protein CML and pentosidine residue contents correlated positively with A1C and fasting plasma glucose, respectively ( 10 ). (diabetesjournals.org)
  • Among them, pyrraline is one of the major Maillard compounds resulting from long time incubation of glucose and proteins. (bmj.com)
  • High-Affinity-Receptor-Mediated Uptake And Degradation Of Glucose-Modified Proteins: A Potential Mechanism For The Removal Of Senescent Macromoleules", Proc. (freepatentsonline.com)
  • Novel Macrophage Receptor for Glucose-Modified Proteins Is Distinct From Previoiusly Described Scavenger Receptors", J. Exp. (freepatentsonline.com)
  • 13 ] Normally the lens contains significant levels of reduced glutathione (GSH), which keeps the proteins in their reduced form. (chiro.org)
  • In addition, even in the absence of RAGE expression, alagebrium attenuated cortical inflammation, as denoted by the reduced expression of monocyte chemoattractant protein-1, intracellular adhesion molecule-1, and the macrophage marker cluster of differentiation molecule 11b. (diabetesjournals.org)
  • Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. (ebscohost.com)
  • Protein oxidation affects crucial intracellular functions and may be considered a 'leitmotif' of degenerating neurons. (biochemj.org)
  • Moreover, our work fixes the rate of growth of intracellular advanced oxidation protein products and the decreasing of protein reactive carbonyl derivatives in neutrophils from patients with chronic kidney disease. (edu.pl)
  • Additionally, there was a trend toward decreased C-reactive protein, and increased nitric oxide levels. (biomedcentral.com)
  • Protein oxidation is the covalent modification of a protein induced directly by reactive oxygen species or indirectly by reaction with the secondary by-products of oxidative stress [2]. (thefreelibrary.com)
  • The in vivo production of glycolaldehyde and other reactive aldehydes by myeloperoxidase may thus play an important pathogenic role by generating AGE products and damaging tissues at sites of inflammation. (nih.gov)
  • The reactive oxygen intermediates (ROI) released are the highly reactive superoxide anion, its dismutation product hydrogen peroxide (H 2 O 2 ), probably the aggressive hydroxyl radical, and products of the myeloperoxidase (MPO)-H 2 O 2 -halide system, such as hypochlorous acid (HOCl) and chloramines ( 9 ). (jimmunol.org)
  • In this study, we determined thiobarbituric acid-reactive substances in plasma and red blood cells and advanced oxidation protein products, nitrosative stress parameters (asymmetric and symmetric dimethylarginine - ADMA and SDMA), and antioxidative parameters (total SH groups and catalase activity). (pubmedcentralcanada.ca)
  • 1.1 Chemical Modification of Proteins by Reactive Oxygen Species (E. Stadtman & R. Levine). (ebooks.com)
  • Direct oxidation of proteins by reactive oxygen species (ROS) was protected the least by green tea. (sigmaaldrich.com)
  • Protein glycation is a slow natural process involving the chemical modification of the reactive amino and guanidine functions in amino acids by sugars and carbohydrates-derived reactive carbonyls. (nih.gov)
  • Using a few well established intermediates such as Schiff base, Amadori product and reactive a-dicarbonyls as milestones and the results of in vitro glycation investigations, an overall detailed mechanistic analysis of protein glycation is presented for the first time. (nih.gov)
  • In the examined neutrophils, advanced oxidation protein products, protein reactive carbonyl derivatives, as well as nucleosomal histones were detected. (edu.pl)
  • The biomarkers known as "advanced glycation end products" or AGE, generate when sugar metabolites interact with proteins. (worldhealth.net)
  • 1. Oxidatively Modified Proteins and Proteomic Technologies. (ebooks.com)
  • Determination of carbonyl content in oxidatively modified proteins. (edu.pl)
  • Study on Mechanism of Soy Protein Oxidation Induced by Lipid Peroxidation Products. (ebscohost.com)
  • Oxidative modification of soy protein by lipid peroxidation products, which was potentially present in a lipoxygenase-catalyzed polyunsaturated fatty acid peroxidation system, was investigated in this study. (ebscohost.com)
  • Green tea antioxidants were found to reduce carbonylation of proteins by lipid peroxidation end products most, followed by advanced glycation end products to a slightly lower extent. (sigmaaldrich.com)
  • Yellow block arrows show movement of plasma protein out of and into the plasma compartment by TER and tissue secretion, respectively, and glomerular filtration of FL- and AGE-modified albumin and FL and AGE free adducts with major recovery of albumin into the renal venous circulation by the albumin retrieval pathway and minor degradation by PTC proteolysis. (diabetesjournals.org)
  • The decrease in blood GSH, plasma GSH, plasma total protein and albumin were significant in these patients compared to controls. (alliedacademies.org)
  • Hence in this study total protein, albumin, thiols , glutathione (GSH) and total antioxidant activity were determined in oral cancer patients to evaluate antioxidant status. (alliedacademies.org)
  • Determining the effects of antioxidants on oxidative stress induced carbonylation of proteins. (sigmaaldrich.com)
  • Differential carbonylation of proteins as a function of in vivo oxidative stress. (edu.pl)
  • Pretreatment with SLs inhibited MCP-1 mRNA and protein expression and suppressed IKK β and NF- κ B p65 phosphorylation and I κ B α degradation. (hindawi.com)
  • The oxidation of fat causes fat degradation within cell membranes, ultimately leading to cell damage. (worldhealth.net)
  • Fat oxidation results in the degradation of fats in cell membranes, which can lead to cell damage. (tufts.edu)
  • In the set- Methods ting of CKD, oxidative damage is a known cause of Animal experiments muscle atrophy, which can contribute to muscle dys- Sprague-Dawley male rats (obtained from the Experimen- function and mark myofibrillar proteins for degradation tal Animal Centre of the Southern Medical University, [7]. (deepdyve.com)
  • Protein modification by the degradation products of ascorbate: formation of a novel pyrrole from the Maillard reaction of L-threose with proteins. (semanticscholar.org)
  • An evaluation of heat on protein oxidation of soy protein isolate or soy protein isolate mixed with soybean oil in vitro and its consequences on redox status of broilers at early age. (thefreelibrary.com)
  • Researches concentrating on protein oxidation showed that protein oxidation could be induced by heat treatment and lipid in different proteins in vitro [3,4]. (thefreelibrary.com)
  • Therefore, the objective of the study was to evaluate protein oxidation of SPI as affected by heat treatment and soybean oil inclusion in vitro and the effect of oxidized protein on redox status of broilers at early age. (thefreelibrary.com)
  • HMGB1 acts as a ligand of receptor for advanced glycation end products (RAGE) and works in synergy with LPS in activating the macrophages in vitro. (jimmunol.org)
  • In our study, we have found that the proinflammatory activity of recombinant HMGB1 protein is correlated with the endotoxin level it contained, and that HMGB1 significantly enhances the activity of LPS to induce proinflammatory cytokines both in vitro and in vivo by promoting the phosphorylation of MAPK p38 and the activation of NF-κB through RAGE. (jimmunol.org)
  • Convenient synthesis of GOLD and MOLD and identification of their oxidation products in vitro and in vivo. (ebscohost.com)
  • All blood sugars are glycated, or cross-linked, with either a protein or a fat molecule, known as a lipid. (bodyecology.com)
  • As we age, proteins tend to undergo destructive changes due largely to oxidation and interactions with sugars and aldehydes. (smart-publications.com)
  • Its deleterious consequences are obvious in the case of long-lived proteins in aged people and are exacerbated by the high blood concentration of sugars in diabetic patients. (nih.gov)
  • However, proteins are often exposed to oxidants or oxidizing conditions during processing and storage, and are vulnerable to oxidative modification [1]. (thefreelibrary.com)
  • Concurrently, oxidants were approved by the Ethics Committee of the Southern may stimulate the pathways of skeletal muscle protein Medical University. (deepdyve.com)
  • The samples treated with ascorbic acid and salt also exhibited significant decrease in free fatty acid and peroxide values at various concentrations.The significance and purpose of conducting this research is the need to explore the use of nonsynthetic preservatives in extending the shelf-life of the proteinous product. (ebscohost.com)
  • Titrable acids, ascorbic acid, and protein dominated in the fruits of I. Pulp oil of II contained. (ebscohost.com)
  • Impact of angiotensin II receptor blocker on plasma levels of adiponectin and advanced oxidation protein products in peritoneal dialysis patients. (biomedsearch.com)
  • The diagram does not show the extremely small amounts of calcium that move into and out of the cells of the body, nor does it indicate the calcium that is bound to the extracellular proteins (in particular the plasma proteins) or to plasma phosphate. (wikipedia.org)
  • In this issue, this is addressed in measurements of plasma protein and skin collagen in the studies by Hanssen et al. (diabetesjournals.org)
  • Glycation adduct residues of plasma protein and skin collagen measured in studies of risk prediction models for vascular complications of diabetes. (diabetesjournals.org)
  • 8 ) measured CML, CEL, and pentosidine residues of plasma protein of patients with type 2 diabetes (T2DM) and also computed an AGE residue content z -score. (diabetesjournals.org)
  • Plasma advanced oxidative protein products are associated with anti-oxidative stress pathway genes and malaria in a longitudinal cohort. (nih.gov)
  • It was observed that there was a significant increase in protein oxidation products and a non significant decrease in plasma protein thiols in oral cancer patients. (alliedacademies.org)
  • 19 Moreover, oxidized plasma proteins in end-stage renal disease patients were shown to interfere with HDL clearance, thereby potentially contributing to the abnormal composition of HDL. (asnjournals.org)
  • Data reported here evaluate the impact of green tea supplementation on oxidative stress induced post-translational modifications (OSi-PTMs) in plasma proteins of Zucker diabetic fatty (ZDF) rats. (sigmaaldrich.com)
  • Specifically, the scientists found an association between ASD and damage to some proteins found in the blood's plasma , or the fluid that carries white and red blood cells. (medicalnewstoday.com)
  • Advanced glycosylated end products and parathyroid hormone generally are recognized as major uremic toxins. (medscape.com)
  • Extracellular HMGB1 may interact with TLR and/or receptor for advanced glycation end products (RAGE). (jimmunol.org)
  • Journal Article] Receptor for advanced glycation end products regulates adipocyte hypertrophy and insulin sensitivity in mice: involvement of toll-like receptor 2. (nii.ac.jp)
  • A receptor nicknamed RAGE, from receptor for advanced glycation end products, is found on many cells, including endothelial cells, smooth muscle, cells of the immune system[which? (wikipedia.org)
  • Activation of the receptor for advanced glycation end products (RAGE) is associated with long-term complications in diabetes mellitus. (wiley.com)
  • The receptor for advanced glycation end products (RAGE) has gained attention as a modulator of complications associated with diabetes mellitus. (wiley.com)
  • The receptor for advanced glycation end products activation can initiate a number of mechanisms that may affect the function of the heart, including release of growths factors and additional RAGE ligands, formation of ROS, angiogenesis, and endothelial dysfunction. (wiley.com)
  • Redox proteomics methods are powerful tools to unravel the complexity of neurodegeneration, by identifying brain proteins with oxidative post-translational modifications that are detrimental for protein function. (biochemj.org)
  • Since AD pathology is age-dependent in DS and shows similarities with AD, identification of common oxidized proteins by redox proteomics in both DS and AD can improve our understanding of the overlapping mechanisms that lead from normal aging to development of AD. (biochemj.org)
  • Measuring the effects of the acute intake of natural products on human biomarker concentrations, such as those related to oxidation and inflammation, can be an advantageous strategy for early clinical research on an ingredient or product. (biomedcentral.com)
  • Oxidative stress, advanced glycation end products, and inflammation (interleukin-1β) were greater in patients with T2DM-SCT compared with the other groups. (diabetesjournals.org)
  • In addition, they showed protective effects against tissue damage and inflammation in the abdominal aorta based on microscopic observation and the analysis of protein expression. (rsc.org)
  • According to the manufacturer, this product is aimed at joints that are faced with inflammation, friction and cartilage degeneration. (jointhealthmagazine.com)
  • On top of this, it controls the production of proteins that are responsible of causing inflammation and destroying joint tissues. (jointhealthmagazine.com)
  • Süer C, Dolu N, Artis AS, Sahin L, Yilmaz A, Cetin A. The effects of long-term sleep deprivation on the long-term potentiation in the dentate gyrus and brain oxidation status in rats. (ijbm.org)
  • Hemoglobin-AGE levels are elevated in diabetic individuals and other AGE proteins have been shown in experimental models to accumulate with time, increasing from 5-50 fold over periods of 5-20 weeks in the retina, lens and renal cortex of diabetic rats. (wikipedia.org)
  • It also reduced the upregulation of genes related to the ubiquitin-proteasome system and 26S proteasome activity, as well as protein and mitochondrial oxidative damage in the muscles of CKD + LPD rats. (deepdyve.com)
  • Protein oxidation can lead to multiple structural changes such as oxidation of side chains of specific amino acid residues or peptide chains, resulting in a decrease in nutritional value of protein [5,6]. (thefreelibrary.com)
  • The amino acid building block in proteins are needed for the proper functioning of platelets, blood vessels. (ebscohost.com)
  • Plant-Based Protein & Fiber To Support Satiety And Digestion Vegan Aminos To Fuel Muscle Growth & Repair Pro Performance Results Complete Vegan Protein Provides 20 Grams Of Plant-Based Protein That Is Complete With All 9 Essential Amino Acids And. (bizrate.com)
  • Accumulation Of Diabetic Rat Peripheral Nerve Myelin By Macrophages Increases With The Presence Of Advanced Glycosylation Endproducts", J. Exp. (freepatentsonline.com)
  • 5 - 9 More recent studies suggest that the HDL proteome is implicated in HDL functionality, identifying HDL-associated proteins involved in lipid metabolism, complement activation, growth factor, and proteolysis regulation. (asnjournals.org)
  • High-Quality, Gluten Free Protein Supports Healthy Metabolism & Lean Muscle Recovery Pro Performance Results As Your Life Becomes Increasingly Hectic, Making Healthy Decisions That Steer You Toward Wellness Can Be Difficult. (bizrate.com)
  • Furthermore, Nepsilon-(carboxymethyl)lysine (CML), a chemically well-characterized AGE product, was generated on RNase A when it was exposed to reagent HOCl-serine, the myeloperoxidase-H2O2-chloride system plus L-serine, or activated human neutrophils plus L-serine. (nih.gov)
  • The purpose of our research was to study oxidative modified proteins, as well as the histone spectrum in neutrophils drawn from patients with chronic kidney disease, and to estimate the ability of neutrophils to form spontaneous neutrophil extracellular traps. (edu.pl)
  • 1.2 The Chemistry of Protein Modifications Elicited By Nitric Oxide and Related Nitrogen Oxides (D. Thomas, et al. (ebooks.com)
  • They can form from pathological oxidation reactions. (townsendletter.com)
  • There is potential that the pathological effects of oxidative stress (OS) associated diseases such as diabetes could be ameliorated with antioxidants, but this will require a clearer understanding of the pathway(s) by which proteins are damaged by OS. (sigmaaldrich.com)
  • This study examined the role of the free radical induced protein oxidation and decreased antioxidant defense mechanism as a causative agent of hypoalbuminemia in patients with oral cancer. (alliedacademies.org)
  • It is widely recognized that oxidation of proteins play an essential role in pathogenesis of cancer [ 4 ] Indeed knockout of various antioxidant defense enzymes promotes cancer development in animals. (alliedacademies.org)
  • Advanced oxidation protein products significantly decrease the expression and activity of CYP1A2 and CYP3A4 via direct activation of the NF-κB pathway. (nature.com)
  • Autophagy is a survival pathway wherein non-functional proteins and organelles are degraded in lysosomes for recycling and energy production. (scielo.br)
  • Studies show that carnosine is effective against all these forms of protein modification. (smart-publications.com)
  • Heating is always essential during soybean meal processing [7], where protein oxidation occurs inevitably. (thefreelibrary.com)
  • The non-enzymatic glycation of proteins occurs through a wide range of concurrent processes comprising condensation, rearrangement, fragmentation, and oxidation reactions. (nih.gov)
  • The last stage of this reaction is the irreversible formation of advanced glycation endproducts (AGE). (biomedcentral.com)
  • Accumulation of advanced glycation endproducts reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage. (semanticscholar.org)
  • Nevertheless, the resistance of extracellular matrix proteins to proteolysis renders their advanced glycation end products less conducive to being eliminated. (wikipedia.org)
  • The microtubule-associated protein Tau plays a crucial role in stabilizing neuronal microtubules. (degruyter.com)
  • Carbon dioxide is a product of most catabolic processes, so it is not depleted like other potential electron acceptors. (wikipedia.org)
  • AGE assays that do not distinguish between protein AGE residues and AGE free adducts are difficult to interpret as they relate to unknown proportions and quantities of both-as applies to an often-used immunoassay for CML ( 3 ). (diabetesjournals.org)
  • In humans, histones in the cell nucleus are richest in lysine, and therefore form the glycated protein N(6)-Carboxymethyllysine (CML). (wikipedia.org)
  • It can minimise uremic symptoms and slow the formation, toxic ions, and metabolic products in the progression of renal failure [1]. (deepdyve.com)
  • Lens proteins typically remain in their reduced form. (chiro.org)
  • The average age of the participants was 65, and all suffered from senile cataracts ranging from minimal to advanced opacification (clouding of the lens). (smart-publications.com)
  • Gd-IgA1 was detected by binding to Helix aspersa agglutinin (HAA) and expressed as total Gd-IgA1 or as degree of galactose deficiency relative to a standard Gd-IgA1 myeloma protein (%HAA). (asnjournals.org)
  • High mobility group box-1 (HMGB1) protein was originally characterized as a nuclear DNA-binding protein, and was described to have an extracellular role when involved in cellular activation and proinflammatory responses. (jimmunol.org)
  • In the present study, we have found that the proinflammatory activity of recombinant HMGB1 proteins is determined by the containing endotoxin level, and HMGB1 that contains few endotoxins fails to stimulate macrophages to secrete proinflammatory cytokines. (jimmunol.org)
  • It is a covalent crosslink, but it has very low protein content compared with other crosslinks, such as glucosepane and nonglycation crosslinks of o,o' -dityrosine, N ε -(γ-glutamyl)lysine and others, suggesting it has limited functional or pathogenic effect in this role ( 2 ). (diabetesjournals.org)
  • Despite advances in renal dialysis, there has been no substantial change in the mortality rate of acute renal failure over the past three decades. (scielo.br)
  • Functional impairment of HDL may contribute to the excess cardiovascular mortality experienced by patients with renal disease, but the effect of advanced renal disease on the composition and function of HDL is not well understood. (asnjournals.org)
  • 20 However, data available regarding the effect of advanced renal disease on HDL functionality are limited, and the effects of renal disease on the first step of reverse cholesterol transport, the efflux of cellular cholesterol from macrophages to HDL, have not been established yet. (asnjournals.org)
  • 21 Accordingly, to understand the role of HDL in chronic and inflammatory diseases, as end-stage renal disease, it is essential to analyze the protein and lipid composition of HDL to reflect its functional state. (asnjournals.org)
  • Proteins are usually glycated through their lysine residues. (wikipedia.org)
  • We previously reported significant decrease of M6P/IGF2-R at the protein level in cancer cells than normal peritumoral ducts of breast tumors. (academicjournals.org)
  • In the majority of cases, oxidative-stress-mediated post-translational modifications cause non-reversible modifications of protein structure that consistently lead to impaired function. (biochemj.org)