Adrenogenital Syndrome: Abnormal SEX DIFFERENTIATION or congenital DISORDERS OF SEX DEVELOPMENT caused by abnormal levels of steroid hormones expressed by the GONADS or the ADRENAL GLANDS, such as in CONGENITAL ADRENAL HYPERPLASIA and ADRENAL CORTEX NEOPLASMS. Due to abnormal steroid biosynthesis, clinical features include VIRILISM in females; FEMINIZATION in males; or precocious sexual development in children.American Hospital Association: A professional society in the United States whose membership is composed of hospitals.Community Networks: Organizations and individuals cooperating together toward a common goal at the local or grassroots level.Multi-Institutional Systems: Institutional systems consisting of more than one health facility which have cooperative administrative arrangements through merger, affiliation, shared services, or other collective ventures.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Ontario: A province of Canada lying between the provinces of Manitoba and Quebec. Its capital is Toronto. It takes its name from Lake Ontario which is said to represent the Iroquois oniatariio, beautiful lake. (From Webster's New Geographical Dictionary, 1988, p892 & Room, Brewer's Dictionary of Names, 1992, p391)Delivery of Health Care: The concept concerned with all aspects of providing and distributing health services to a patient population.Organizational Case Studies: Descriptions and evaluations of specific health care organizations.Models, Organizational: Theoretical representations and constructs that describe or explain the structure and hierarchy of relationships and interactions within or between formal organizational entities or informal social groups.Syndrome: A characteristic symptom complex.Adrenal Hyperplasia, Congenital: A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.Steroid 21-Hydroxylase: An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).17-alpha-Hydroxyprogesterone: A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Pregnanetriol: A metabolite of 17-ALPHA-HYDROXYPROGESTERONE, normally produced in small quantities by the GONADS and the ADRENAL GLANDS, found in URINE. An elevated urinary pregnanetriol is associated with CONGENITAL ADRENAL HYPERPLASIA with a deficiency of STEROID 21-HYDROXYLASE.Hydroxyprogesterones: Metabolites or derivatives of PROGESTERONE with hydroxyl group substitution at various sites.Fludrocortisone: A synthetic mineralocorticoid with anti-inflammatory activity.Adrenal Rest Tumor: Neoplasm derived from displaced cells (rest cells) of the primordial ADRENAL GLANDS, generally in patients with CONGENITAL ADRENAL HYPERPLASIA. Adrenal rest tumors have been identified in TESTES; LIVER; and other tissues. They are dependent on ADRENOCORTICOTROPIN for growth and adrenal steroid secretion.Adrenocortical Hyperfunction: Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.Osteoprotegerin: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.Glucocorticoids: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.Bone and Bones: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.Hormone Replacement Therapy: Therapeutic use of hormones to alleviate the effects of hormone deficiency.Bone Density: The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.Estrogen Replacement Therapy: The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.Dexamethasone: An anti-inflammatory 9-fluoro-glucocorticoid.Congenital Hypothyroidism: A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA.Trypsinogen: The inactive proenzyme of trypsin secreted by the pancreas, activated in the duodenum via cleavage by enteropeptidase. (Stedman, 25th ed)Neonatal Screening: The identification of selected parameters in newborn infants by various tests, examinations, or other procedures. Screening may be performed by clinical or laboratory measures. A screening test is designed to sort out healthy neonates (INFANT, NEWBORN) from those not well, but the screening test is not intended as a diagnostic device, rather instead as epidemiologic.Dried Blood Spot Testing: Techniques for using whole blood samples collected on filter paper for a variety of clinical laboratory tests.Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA.Thyrotropin: A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.Endocrinology: A subspecialty of internal medicine concerned with the metabolism, physiology, and disorders of the ENDOCRINE SYSTEM.WashingtonBritish Columbia: A province of Canada on the Pacific coast. Its capital is Victoria. The name given in 1858 derives from the Columbia River which was named by the American captain Robert Gray for his ship Columbia which in turn was named for Columbus. (From Webster's New Geographical Dictionary, 1988, p178 & Room, Brewer's Dictionary of Names, 1992, p81-2)Academic Medical Centers: Medical complexes consisting of medical school, hospitals, clinics, libraries, administrative facilities, etc.SwedenHospital Bed Capacity, 100 to 299United StatesQuestionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Endocrine System Diseases: Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Amenorrhea: Absence of menstruation.Nursing Diagnosis: Conclusions derived from the nursing assessment that establish a health status profile for the patient and from which nursing interventions may be ordered.Hypothalamic Diseases: Neoplastic, inflammatory, infectious, and other diseases of the hypothalamus. Clinical manifestations include appetite disorders; AUTONOMIC NERVOUS SYSTEM DISEASES; SLEEP DISORDERS; behavioral symptoms related to dysfunction of the LIMBIC SYSTEM; and neuroendocrine disorders.Oligomenorrhea: Abnormally infrequent menstruation.Galactorrhea: Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.Menstruation: The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.Puberty: A period in the human life in which the development of the hypothalamic-pituitary-gonadal system takes place and reaches full maturity. The onset of synchronized endocrine events in puberty lead to the capacity for reproduction (FERTILITY), development of secondary SEX CHARACTERISTICS, and other changes seen in ADOLESCENT DEVELOPMENT.Primary Ovarian Insufficiency: Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.Menstruation Disturbances: Variations of menstruation which may be indicative of disease.Puberty, Delayed: The lack of development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations above the mean age at onset of PUBERTY in a population. Delayed puberty can be classified by defects in the hypothalamic LHRH pulse generator, the PITUITARY GLAND, or the GONADS. These patients will undergo spontaneous but delayed puberty whereas patients with SEXUAL INFANTILISM will not.Embryology: The study of the development of an organism during the embryonic and fetal stages of life.Cyclization: Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Aldehydes: Organic compounds containing a carbonyl group in the form -CHO.AcroleinStereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)ButanonesPentanones: 5-carbon straight-chain or branched-chain ketones.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Cycloparaffins: Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a ring structure and each of the ring carbon atoms is joined to two hydrogen atoms or alkyl groups. The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (From Sax, et al., Hawley's Condensed Chemical Dictionary, 11th ed)
(1/3) KORSAKOFF'S SYNDROME ASSOCIATED WITH ADRENAL VIRILISM.

Korsakoff's syndrome of obscure etiology was observed in a 34-year-old single woman with an 11-year history of hirsutism and mood swings, and previous hospitalizations for mania three years ago and depression 11 years ago.Recently the virilism had intensified with increased muscularity and coarsening of facial features. The 24-hour urinary 17-ketosteroids ranged between 14.4 mg. and 21.5 mg. and were suppressed by dexamethasone. The 17-hydroxycorticosteroid excretion was normal. These and other findings suggested a diagnosis of adrenal virilism due to adrenocortical hyperplasia. In the absence of other discernible causes it appeared that the adrenal pathology was responsible for the Korsakoff's syndrome. Both conditions responded well to glucocorticoid therapy although low doses were necessary to avoid mania.It is speculated that the encephalopathy was due to an associated adrenal insufficiency. Although hypoadrenalism is accepted as a complication of only the infant form of adrenal virilism, it is noteworthy that this patient had pathological pigmentation of her skin.  (+info)

(2/3) Microscope-assisted reduction clitoroplasty used to treat two patients with clitoromegaly.

We report 2 cases of clitoromegaly, 1 in a patient with true hermaphroditism, and the other in a patient with adrenogenital syndrome. Both were treated surgically with reduction clitoroplasty. There are 3 different clitoroplasty procedures: clitorectomy, clitoral recession, and reduction clitoroplasty. Reduction clitoroplasty with preservation of the neurovascular bundle is considered superior in terms of formation of the external genitals and sensation. However, the disadvantages are that detachment of the neurovascular bundle from the clitoral shaft is difficult and that there is a high possibility of sensory and blood flow disorders in the clitoris. In an attempt to achieve safe and reliable surgical manipulation, we used a surgical microscope (OPMI 6-SDFC, Carl Zeiss Surgical GmbH, magnification x8) to detach the neurovascular bundle from the clitoral shaft in our 2 patients. Our impression is that our efforts were extremely effective. Furthermore, our experience leads us to believe that the procedure for neurovascular bundle detachment required in reduction clitoroplasty is not particularly difficult if performed with a surgical microscope by a plastic surgeon who regularly performs microsurgery. Because the procedure can be performed simply and safely, we believe that reduction clitoroplasty with preservation of the neurovascular bundle is the best overall of the 3 clitoroplasty procedures.  (+info)

(3/3) Role of a disordered steroid metabolome in the elucidation of sterol and steroid biosynthesis.

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*  Pregnanetriol
Elevated urine pregnanetriol levels suggest adrenogenital syndrome. In monitoring treatment with cortisol replacement, elevated ...
*  Achard-Thiers syndrome
... combines the features of adrenogenital syndrome and Cushing syndrome. It is also known as diabetic- ... Achard-Thiers syndrome affects mostly postmenopausal women and comprises diabetes mellitus, deep voice, hirsutism or ... Pal, Lubna (2013). Polycystic Ovary Syndrome: Current and Emerging Concepts. Springer Science & Business Media. p. 97. ISBN ... bearded woman syndrome (diabète des femmes à barbe) and occurs mainly in post-menopausal women. The disease is named for Emile ...
*  Hydrocortisone
Uses include conditions such as adrenocortical insufficiency, adrenogenital syndrome, high blood calcium, thyroiditis, ...
*  Clitoromegaly
Genital findings in the female pseudo-hermaphroditism of the congenital adrenogenital syndrome; morphology, frequency, ... It can also be caused by the autosomal recessive congenital disorder known as Fraser syndrome. In acquired clitoromegaly, the ... van Haelst MM, Scambler PJ, Hennekam RC (December 2007). "Fraser syndrome: a clinical study of 59 cases and evaluation of ... "Polycystic Ovarian Syndrome". Retrieved 2008-09-28. Horejsí J (June 1997). "Acquired clitoral enlargement. Diagnosis and ...
*  Fludrocortisone
... is a corticosteroid which is used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. In adrenal ... Fludrocortisone has been used in the treatment of cerebral salt wasting syndrome. It is used primarily to replace the missing ... Fludrocortisone is also a confirmation test for diagnosing Conn's syndrome (aldosterone producing-adrenal adenoma), the ... fludrocortisone is the first line of treatment for orthostatic intolerance and postural orthostatic tachycardia syndrome (POTS ...
*  Lennox Broster
The condition was known at the time as "adreno-genital syndrome", although the term now used is congenital adrenal hyperplasia ... "The adreno-genital syndrome associated with cortical hyperplasia; the results of unilateral adrenalectomy". British Journal of ...
*  List of diseases (A)
Adrenal insufficiency Adrenal macropolyadenomatosis Adrenal medulla neoplasm Adrenocortical carcinoma Adrenogenital syndrome ... syndrome Aarskog-Ose-Pande syndrome Aarskog syndrome Aase-Smith syndrome Anti amnistic syndrome Aase syndrome ABCD syndrome ... syndrome Akesson syndrome Aksu-Stckhausen syndrome Al Awadi Teebi Farag syndrome Al Frayh Facharzt Haque syndrome Al Gazali Al ... Alien hand syndrome Alkaptonuria Allain-Babin-Demarquez syndrome Allan-Herndon-Dudley syndrome Allanson-Pantzar-McLeod syndrome ...
*  List of MeSH codes (C19)
... adrenogenital syndrome MeSH C19.391.775.260 --- freemartinism MeSH C19.391.775.309 --- gonadal dysgenesis MeSH C19.391.775.309. ... cushing syndrome MeSH C19.053.800.604 --- hyperaldosteronism MeSH C19.053.800.604.249 --- bartter syndrome MeSH C19.246.099.500 ... kallmann syndrome MeSH C19.391.482.629 --- klinefelter syndrome MeSH C19.391.482.814 --- sexual infantilism MeSH C19.391. ... digeorge syndrome MeSH C19.700.159.750 --- diabetes insipidus, neurogenic MeSH C19.700.159.875 --- wolfram syndrome MeSH ...
*  ICD-10 Chapter IV: Endocrine, nutritional and metabolic diseases
Other Cushing's syndrome (E24.5) Cushing's syndrome, unspecified (E25) Adrenogenital disorders (E25.0) Congenital adrenogenital ... Tietz syndrome (ILDS E70.358) Hermansky-Pudlak syndrome (ILDS E70.360) Cross syndrome (ILDS E70.380) (E70.8) Other disorders of ... Gilbert's syndrome (E80.5) Crigler-Najjar syndrome (E80.6) Other disorders of bilirubin metabolism Dubin-Johnson syndrome ... Cushing's syndrome (E24.0) Pituitary-dependent Cushing's disease (E24.1) Nelson's syndrome (E24.2) Ectopic ACTH syndrome (E24.3 ...
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ହାଇଡ୍ରୋକର୍ଟିଜୋନ (ଇଂରାଜୀ ଭାଷାରେ Hydrocortisone, ଏକ ବିକ୍ରୟ ନାମ କର୍ଟେଫ/Cortef) ନାମ ଦିଆଯାଏ ଯେତେବେଳେ ହରମୋନ କର୍ଟିଜୋଲକୁ (cortisol) ଔଷଧ ଆକାରରେ ଯୋଗାଇ ଦିଆଯାଏ ।[୨] ଏହି ଔଷଧ ବ୍ୟବ‌ହାର କରାଯାଉଥିବା ରୋଗମାନଙ୍କର ନାମ: ଆଡ୍ରେନାଲ ଇନସଫିସିଏନ୍ସି (adrenocortical insufficiency, ଆଡ୍ରେନୋଜେନିଟାଲ ସିଣ୍ଡ୍ରୋମ (adrenogenital syndrome), ହାଇପୋକ୍ୟାଲସେମିଆ (high blood calcium, ଥାଇରଏଡାଇଟିସ (thyroiditis), ରିଉମାଟଏଡ ଆର୍ଥ୍ରାଇଟିସ, ଡର୍ମାଟାଇଟିସ (dermatitis), ଆଜ୍‌ମା, ଓ ସିଓପିଡି ।[୧] ଆଡ୍ରେନୋକର୍ଟିକାଲ ...
Adrenogenital Syndrome, Allergic Rhinitis, Asthma, Asthma, acute, Asthma, Maintenance, Allergy (Allergies), Dermatologic Lesion, Gout, Acute, Immunosuppression, Inflammatory Conditions, Neuralgia, Osteoarthritis, Rheumatoid Arthritis, ...
Diagnosis Code E25.8 information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
Symptoms of the following disorders can be similar to those of Achard-Thiers. Comparisons may be useful for a differential diagnosis:. Acquired adrenogenital syndrome is a rare endocrine disorder that occurs because of a tumor in the adrenal glands which causes the overproduction of androgens. In an adult female the symptoms may include a male pattern of hair growth, loss of hair on the head, acne, deepening voice, and abnormally large muscles.. Empty sella syndrome is a rare brain disorder that may be inherited or acquired. The acquired form of the disease may occur as a result of a tumor in the pituitary gland or radiation to that area. Symptoms may include headaches, impaired vision, and/or obesity. Some people with empty sella syndrome cannot tolerate cold temperatures and may also have abnormally high blood pressure (hypertension). In women this disorder is associated with an increase in body hair and a male pattern of hair growth. (For more information on this disorder, choose "Empty ...
Adrenogenitale Syndrome, in the Girl vs. Hypospadias, Severe Type. Adrenogenitale Syndrome, in the Girl vs. Hypospadias, Severe Type Left picture: The further clinical and additional examinations display an adrenogenital syndrome in a girl (female pseudohermaphrodidism). The hairy zone and the pigmentation which is abnormal for the age of the girl are signs of a masculinization of the external genitals and call for an especially careful clinical examination; notice for that also the picture at the bottom of the same side. Right picture: The diagnosis is a severe type of a hypospadias. The findings which are mentioned in the picture at the top in the contralateral patient are missing in this child. Left picture: Toddler with a penis-like structure and labioscrotal folds on both sides of it having a similar pigmentation as the penis. Hairy suprapubic region. Right picture: Toddler with slack labioscrotal folds and trumpet-like structure in between. The color of the skin of the external genitals is ...
Congenital adrenal hyperplasia (CAH), also known as the "adrenogenital syndrome," is an uncommon condition caused by a congenital defect in one of several enzymes that take part in the chain of reactions whereby cortisol is manufactured from its precursors. There are at least six fairly well-defined variants of CAH that result from the various enzyme defects. The most common of these are types I and II, which are due to C21-hydroxylase enzyme deficiency. All CAH variants are inherited as autosomal recessive traits. The clinical and laboratory findings depend on which metabolic pathway-and which precursor in the metabolic pathway- is affected. All variants affect the glucocorticoid (cortisol) pathway in some manner. In CAH due to 21-hydroxylase defect (types I and II) and in CAH type III, although formation of cortisone and cortisol is blocked, the precursors of these glucocorticoids are still being manufactured. Most of the early precursors of cortisone are estrogenic compounds, which also are ...
Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addisons disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions ...
Clitoromegaly (or macroclitoris) is an abnormal enlargement of the clitoris that is mostly congenital or acquired, though deliberately induced clitoris enlargement as a form of female genital body modification is achieved through various uses of anabolic steroids, including testosterone, and may also be referred to as clitoromegaly. Clitoromegaly is not the same as normal enlargement of the clitoris seen during sexual arousal. The different grade of genital ambiguity is commonly measured by the Prader classification, which ranges, in ascending order of masculinisation, from 1: female external genitalia with clitoromegaly through 5: pseudo-phallus looking like normal male external genitalia. Clitoromegaly is a rare condition and can be either present by birth or acquired later in life. If present at birth, congenital adrenal hyperplasia can be one of the causes, since in this condition the adrenal gland of the female fetus produces additional androgens and the newborn baby has ambiguous genitalia ...
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ZAMBELLI, Anthony B.; CLIFT, Sarah J.; GERBER, David e SCHOEMAN, Johan P.. Hypercalcaemic multicentric lymphoma in a dog presenting as clitoromegaly. J. S. Afr. Vet. Assoc. [online]. 2013, vol.84, n.1, pp.1-8. ISSN 2224-9435.. Clitoromegaly is a clinical manifestation of various local and systemic conditions in all species. The external genitalia are a very rare site of primary or metastatic lymphoma in canines, with only one previously-reported case in a dog and only sparse reports in the medical literature. Lymphoma is also very rare in dogs less than four years of age. This account reports on a T-cell multicentric lymphoma in a 16-month-old Basset hound presented primarily for clitoromegaly. The patient survived for 68 days with cyclophosphamide-vincristine-prednisolone therapy. The causes of clitoromegaly in all species, including humans, are tabulated with references.. ...
What is Korsakoffs Syndrome? Symptoms, Causes and Treatment. This is a neurological disorder that is primarily caused by the decreased amount of vitamin B1 or thiamine....
Learn more about Korsakoffs Syndrome at Reston Hospital Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Learn more about Korsakoffs Syndrome at Reston Hospital Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Received for publication March 28, 1955.From the Departments of Medicine and Pathology, University of Colorado Medical School and Denver General Hospital, Denver, Colorado.Originally presented at a Combined Regional Meeting of The American College of Physicians and The Colorado Society of Internal Medicine, Colorado Springs, Colorado, January 15, 1955.†Trainee, National Cancer Institute.‡This patients case was abstracted prior to her death by Downing et al., in a paper on retroperitoneal radiography.1 The case was reported in abbreviated form, again prior to death, by Taylor and Snow,2 in a paper on "Adrenal Virilism in the Female Child and Adult ...
Just as a patient suffering from Korsakoffs Syndrome, which affects the memory, may confabulate - create a false account in order to explain their solution and completely believe in it - and just as an act of architectural restoration may involve a certain amount of creative guesswork, so too goes the story of this wretched scrap of literature. Repeatedly destroyed, savaged, battered and blown to bits, only to be rebuilt from a few scattered remains by a different writer every time, it has survived long enough to be worth my presenting to you in bound form, with every past iteration having been reclaimed using sorcery, and the full story of its life painstakingly put back together. I, Dr Fulminare, give you the one and only Korsakoffs Paper Chain.. Featuring new poems by:. David Floyd, Charlotte Geater, Aiko Harman, Sarah Howe, Edward Mackay, Richard OBrien, Adham Smart, James Wilkes, Chrissy Williams and Tony Williams.. ...
We investigated the role of feedback processing in decision making under risk conditions in 50 patients with amnesia in the course of alcoholic Korsakoffs syndrome (KS). Half of the patients were administered the Game of Dice Task (GDT) and the remaining 25 patients were examined with a modified version of the GDT in which no feedback was provided. Patients results in the GDT and in the modified version were compared with that of 50 healthy subjects of whom 25 subjects performed the original GDT and 25 performed the modified version. While performance on the original GDT was superior to performance on the modified GDT in healthy subjects, KS patients performed similarly on both the GDT with and GDT without feedback. Performance on both task versions was correlated with categorization and set-shifting. The findings indicate that amnesic patients do not profit from receiving feedback for their decisions in explicit risk conditions. (C) 2008 Elsevier Inc. All rights reserved ...
Deficiency of nutrients such as minerals, proteins and vitamins are found in alcoholics. Low blood potassium, magnesium, calcium, zinc and phosphorus can occur in alcoholics. Vitamins like thiamine (B1), nicotinic acid (B3), pyridoxine (B6), folic acid, ascorbic acid (Yitamin C) and vitamin A may be deficient in alcoholics. Thiamine (B1) deficiency causes Wernickes and Korsakoffs syndrome.. Wernicke syndrome (= Wernicke disease or encephalopathy) is characterized by mental disturbance, paralysis of eye movements and ataxia (a loss of the power of muscular co-ordination) of gait (manner of or carriage in walking). Korsakoffs syndrome (= Korsakoffs psychosis) is characterised by confusion and severe impairment of memory, especially for recent events.. ...
RECOGNITION A recognition test differs from a recall test in that it provides the correct response embedded within a list of several other alternatives. The patient must choose the correct response from among these alternatives during a specified retrieval period. In other words, instead of having to try to recall the responses on his own, the patient is provided a set of responses from which to choose. The task could be either: 30 2. THE ORIGINAL MEMORY MODEL to select which responses he learned, or to tell which responses were originally paired with which stimuli, or to arrange the responses in a particular order. On the other hand, the amnesic patients recency performance was nearly normal. T h e ramifications of this outcome will be discussed in the next chapter, but it is important to note here that the only items that seemed to attain L T M status in the amnesics memory were the first one or two presented. In an attempt to determine at least one of the factors underlying alcoholic ...
R 75251, a new inhibitor of steroid biosynthesis.: R 75251, a new imidazole derivative, inhibited the conversion of androgens to estrogens, of progestins to and
DM v Y City Council [2017] EWCOP 13, Bodey J, 15 June 2017. On a s 21A MCA 2005 application the court determined that it was in DMs best interests to remain in the current care home where he was forbidden to drink alcohol rather than move to a home that allowed the consumption of alcohol.. DM suffered from Korsakoffs Syndrome and lacked capacity to make decisions as to his care and residence and as to drinking alcohol. He needed support with all aspects of daily living. DM wished to drink alcohol. Expert evidence established that in view of his cirrhosis of the liver even if he were to drink a relatively low level of alcohol his life expectancy would be significantly reduced. The judge was referred to Aintree University Hospital NHS Foundation Trust v James [2013] UKSC 67 and Local Authority X v MM and Another [2007] EWHC 2003 including the passage in Munby Js judgment, "What good is making someone safe if it merely makes them miserable?". Bodey J considered it a finely balanced decision, and ...
Behavioural Neurology is a peer-reviewed, Open Access journal that provides a platform for researchers and clinicians working in the areas of neurology, cognitive neuroscience, neuropsychology and neuropsychiatry.
Korsakoffs Syndrome is an inability to form new memories because of damage to the brains temporal lobes after years of alcohol abuse. Sufferers make up stories and then make up new stories to cover the mistakes and falsehoods in the first series of stories. According to Drs G dYdewalle and I Van Damme of the Department of Psychology at the University of Leuven in Belgium, writing in the ...
The expression pattern of genes involving in sex steroid biosynthesis pathway in DHT-treated rat ovaries. (A) A modified steroid biosynthesis pathway from [53].
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Plastic Surgery. (Brännskadecentrum)ORCID iD: 0000-0002-9735-1434 ...
Performance of patients with Korsakoffs syndrome and herpes encephalitis was compared on a retrograde amnesia (RA) test, asking subjects to recall and recognize the definitions of words that had come into the language at different time periods. Performance was also compared on a related test in which participants were asked to produce the words to definitions they were given in free recall and cued recall versions. It was hypothesized that, if the temporal gradient in remote memory results from a shift of information from episodic to semantic memory, then there should be a temporal gradient on these tasks, possibly steeper (i.e., greater relative sparing of early memories) in the patients in the Korsakoff group than in the herpes encephalitis group, who have widespread temporal lobe damage. Furthermore, in comparing semantic and episodic remote memory tests, consolidation theory would predict uniform temporal gradients across such tasks, whereas multiple trace theory would predict a ...
Adrenogenital Syndrome  Adrenogenital Syndrome
... - 25 Studies Found. Status. Study Completed. Study Name: Examining Genetic Differences Among People With ...
more infohttp://webhealthnetwork.com/clinicaltrials-search.php?q=Adrenogenital+Syndrome
Congenital adrenal hyperplasia facts, information, pictures | Encyclopedia.com articles about Congenital adrenal hyperplasia  Congenital adrenal hyperplasia facts, information, pictures | Encyclopedia.com articles about Congenital adrenal hyperplasia
adrenogenital syndrome (ă-dree-noh-jen-it-ăl) n. a hormonal disorder resulting from abnormal steroid production by the adrenal ... adrenogenital syndrome A Dictionary of Nursing © A Dictionary of Nursing 2008, originally published by Oxford University Press ... It is also called adrenogenital syndrome.. Causes and symptoms. CAH is an inherited disorder. It is a recessive disease, which ... CAH is also called adrenogenital syndrome or 21-hydroxylase deficiency.. Demographics. CAH, a genetic disorder, is the most ...
more infohttps://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/congenital-adrenal-hyperplasia
adrenal rest tumor disease finding 2005:2010[pubdate] *count=100 - BioMedLib™ search engine  adrenal rest tumor disease finding 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Adrenogenital Syndrome / therapy. Glucocorticoids / therapeutic use. Mineralocorticoids / therapeutic use. Steroid 21- ... Knape P, Reisch N, Dörr HG, Reincke M, Quinkler M: [Treatment of adult men with congenital adrenal hyperplasia syndrome due to ... Nelson Syndrome. Ovarian Neoplasms / complications. *Genetic Alliance. consumer health - BabyFirstTest - Congenital Adrenal ... We report a case of OART in a patient with congenital adrenal hyperplasia who developed Nelsons syndrome after bilateral ...
more infohttp://www.bmlsearch.com/?kwr=adrenal+rest+tumor+disease+finding+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
Female pseudohermaphroditism in congenital adrenogenital synd...  Female pseudohermaphroditism in congenital adrenogenital synd...
Female pseudohermaphroditism in congenital adrenogenital syndrome as an incidental intraoperative finding in a 68-year-old ... Female pseudohermaphroditism in congenital adrenogenital syndrome as an incidental intraoperative finding in a 68-year-old ...
more infohttps://www.mysciencework.com/publication/show/female-pseudohermaphroditism-congenital-adrenogenital-syndrome-incidental-intraoperative-finding-68-year-old-patient-338dd97e
Congenital Adrenal Hyperplasia - Articles on Medical Diseases and Conditions  Congenital Adrenal Hyperplasia - Articles on Medical Diseases and Conditions
Congenital adrenal hyperplasia (CAH), also known as the "adrenogenital syndrome," is an uncommon condition caused by a ... Product Transfusion Blood Transfusions Cerebrospinal Fluid Examination Classification of Anemia CSF Culture Cushings syndrome ... Tests Leukemia Liver Tract Tests Lymphomas Medical Parasitology Mobility Multiple Sclerosis Myeloproliferative Syndromes ...
more infohttp://med-life.net/2009/12/22/congenital-adrenal-hyperplasia/
Genetics and clinical presentation of classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency  Genetics and clinical presentation of classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency
The testicular tumor of the adrenogenital syndrome. A report of six cases and review of the literature on testicular masses ... Testicular masses in association with adrenogenital syndrome: US findings. Radiology 1992; 183:425. ... of remnant and ectopic adrenal tissues with cosyntropin-stimulated 18F-FDG-PET/CT in a patient with Nelson syndrome with ...
more infohttp://www.uptodate.com/contents/genetics-and-clinical-presentation-of-classic-congenital-adrenal-hyperplasia-due-to-21-hydroxylase-deficiency
Testicular Tumors of Adrenogenital Syndrome (TTAG) - American Urological Association  Testicular Tumors of Adrenogenital Syndrome (TTAG) - American Urological Association
Welcome to the updated version of Pathology for Urologists! This program was designed to help Urology residents and fellows familiarize themselves with the pathologic features of common urologic entities. This will serve not only as a resource tool for your review but also as a quick reference guide to urologic pathology.
more infohttps://www.auanet.org/education/auauniversity/education-products-and-resources/pathology-for-urologists/testis/sex-cord-stromal-tumors/testicular-tumors-of-adrenogenital-syndrome
Adrenogenital Syndrome)? - ?????   ?????????   ???????  999  Adrenogenital Syndrome)? - ????? ????????? ??????? 999
Edwards " Syndrome). ????? ?? (Adie"S Syndrome), ????? ???????? (Holmes-Adie Syndrome). ????? ?? -????? (Holmes-Adie Syndrome) ... Scalenus Syndrome, Thoracic Outlet Syndrome). ????? ????? -????????? (Fragile-X Syndrome). ????? ???????? (?? leod"S Syndrome ... Adamsstokes Syndrome). ????? ???????????? (Thalamic Syndrome). ????? ?????? (Turner"S Syndrome). ????? ?? (Tietze"S Syndrome ... Budd- Chiari Syndrome). ????? ????? (Banti"S Syndrome). ????? ???????? (Briquet"S Syndrome). ????? ?????-????? (Brown-Sequard ...
more infohttp://www.tridevyatki.ru/lib/index.php?chapter=414&word=37234
Adrenogenital Syndrome)? - ?????   ?????????   ???????  999  Adrenogenital Syndrome)? - ????? ????????? ??????? 999
Edwards " Syndrome). ????? ?? (Adie"S Syndrome), ????? ???????? (Holmes-Adie Syndrome). ????? ?? -????? (Holmes-Adie Syndrome) ... Scalenus Syndrome, Thoracic Outlet Syndrome). ????? ????? -????????? (Fragile-X Syndrome). ????? ???????? (?? leod"S Syndrome ... Adamsstokes Syndrome). ????? ???????????? (Thalamic Syndrome). ????? ?????? (Turner"S Syndrome). ????? ?? (Tietze"S Syndrome ... Budd- Chiari Syndrome). ????? ????? (Banti"S Syndrome). ????? ???????? (Briquet"S Syndrome). ????? ?????-????? (Brown-Sequard ...
more infohttp://www.tridevyatki.ru/lib/index.php?chapter=413&word=37136
Ventricular Tachycardia Associated With Hyperkalemia: Occurrence in an Infant Aged 13 Days With Adrenogenital Syndrome | JAMA...  Ventricular Tachycardia Associated With Hyperkalemia: Occurrence in an Infant Aged 13 Days With Adrenogenital Syndrome | JAMA...
Ventricular Tachycardia Associated With Hyperkalemia: Occurrence in an Infant Aged 13 Days With Adrenogenital Syndrome. ... This contribution describes a newborn infant with salt-losing adrenogenital syndrome who developed ventricular tachycardia at ... Occurrence in an Infant Aged 13 Days With Adrenogenital Syndrome. Am J Dis Child. 1969;117(6):706-709. doi:10.1001/archpedi. ...
more infohttps://jamanetwork.com/journals/jamapediatrics/article-abstract/503110
Triamcinolone Acetonide Monograph for Professionals - Drugs.com  Triamcinolone Acetonide Monograph for Professionals - Drugs.com
Adrenogenital Syndrome. Lifelong glucocorticoid treatment of congenital adrenogenital syndrome.b. In salt-losing forms, ... Loefflers Syndrome. Symptomatic relief of acute manifestations of symptomatic Loefflers syndrome not manageable by other ... Nephrotic Syndrome and Lupus Nephritis. Treatment of idiopathic nephrotic syndrome without uremia.d ... Nephrotic Syndrome and Lupus Nephritis. Oral. Average 16-20 mg (up to 48 mg) daily, until diuresis occurs.j After diuresis ...
more infohttps://www.drugs.com/monograph/triamcinolone-acetonide.html
Methylprednisolone Sodium Succinate Monograph for Professionals - Drugs.com  Methylprednisolone Sodium Succinate Monograph for Professionals - Drugs.com
Adrenogenital Syndrome. Lifelong glucocorticoid treatment of congenital adrenogenital syndrome.a c. In salt-losing forms, ... Adrenogenital Syndrome prednisone, dexamethasone, methylprednisolone, Medrol, Medrol Dosepak, Decadron, More.... 15 more ... Adrenogenital Syndrome. IM. Methylprednisolone acetate: 40 mg every 2 weeks.d m ... Nephrotic Syndrome and Lupus Nephritis. Treatment of idiopathic nephrotic syndrome without uremia.a d e f ...
more infohttps://www.drugs.com/monograph/methylprednisolone-sodium-succinate.html
Endocrine Flashcards by Margaret Holland | Brainscape  Endocrine Flashcards by Margaret Holland | Brainscape
Describe the clinical features of the three most important syndromes caused by adrenocortical hyperfunction. ...
more infohttps://www.brainscape.com/flashcards/endocrine-3531477/packs/4824663
April 1993 - Volume 91 - Issue 5 : Plastic and Reconstructive Surgery  April 1993 - Volume 91 - Issue 5 : Plastic and Reconstructive Surgery
Clitoroplasty for Clitoromegaly Due to Adrenogenital Syndrome Without Loss of Sensitivity. Sagehashi, Nobuyuki; Edgerton, ... Clitoroplasty for Clitoromegaly Due to Adrenogenital Syndrome Without Loss of Sensitivity. Sagehashi, Nobuyuki ...
more infohttps://journals.lww.com/plasreconsurg/toc/1993/04001
August 1956 - Volume 11 - Issue 4 : Obstetrical & Gynecological Survey  August 1956 - Volume 11 - Issue 4 : Obstetrical & Gynecological Survey
CORTISONE AND ADRENALECTOMY IN TREATMENT OF STERILITY IN WOMEN WITN ADRENOGENITAL SYNDROME. Wilhelm, Seymour F.; Marks, Robert ...
more infohttps://journals.lww.com/obgynsurvey/toc/1956/08000
Clinical Evaluation of NeoPlex4 Assay and NeoPlex System - Full Text View - ClinicalTrials.gov  Clinical Evaluation of NeoPlex4 Assay and NeoPlex System - Full Text View - ClinicalTrials.gov
Adrenogenital Syndrome. Pancreatic Diseases. Digestive System Diseases. Lung Diseases. Respiratory Tract Diseases. Genetic ...
more infohttps://clinicaltrials.gov/ct2/show/NCT01488721?cond=%22Congenital+hypothyroidism%22&rank=6
Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia - Full Text View - ClinicalTrials.gov  Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia - Full Text View - ClinicalTrials.gov
Adrenogenital Syndrome. Adrenocortical Hyperfunction. Hyperandrogenism. Pathologic Processes. Adrenal Gland Diseases. Endocrine ... Short-term overtreatment with glucocorticoids can lead to iatrogenic Cushing syndrome and long-term use has been associated ...
more infohttps://www.clinicaltrials.gov/ct2/show/NCT01859312?term=HYDROXYPROGESTERONE&
The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or...  The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or...
Adrenogenital Syndrome. Congenital Abnormalities. Metformin. Citric Acid. Clomiphene. Enclomiphene. Zuclomiphene. Hypoglycemic ... Polycystic Ovary Syndrome Anovulation Oligoovulation Infertility Hyperandrogenism Drug: Metformin Drug: Clomiphene citrate Drug ... Genetics Home Reference related topics: Polycystic ovary syndrome Drug Information available for: Clomiphene citrate Metformin ... Polycystic Ovarian Syndrome. Chronic Anovulation. Chronic Oligoovulation. Infertility. Hyperandrogenism. Metformin. Ovulation ...
more infohttps://www.clinicaltrials.gov/ct2/show/NCT00413179
  • Women with polycystic ovary syndrome (PCOS), defined as chronic oligoovulation or anovulation and hyperandrogenism, are primarily treated with clomiphene citrate as first line therapy if they desire pregnancy. (clinicaltrials.gov)
  • Polycystic Ovary Syndrome: Current and Emerging Concepts. (wikipedia.org)