Excision of one or both adrenal glands. (From Dorland, 28th ed)
Tumors or cancer of the ADRENAL GLANDS.
A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
A benign neoplasm of the ADRENAL CORTEX. It is characterized by a well-defined nodular lesion, usually less than 2.5 cm. Most adrenocortical adenomas are nonfunctional. The functional ones are yellow and contain LIPIDS. Depending on the cell type or cortical zone involved, they may produce ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE.
An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Pathological processes of the ADRENAL GLANDS.
A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA.
A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Tumors or cancers of the ADRENAL CORTEX.
An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).
A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.
A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.
Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.
A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.
An anti-inflammatory 9-fluoro-glucocorticoid.
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Surgical removal or destruction of the hypophysis, or pituitary gland. (Dorland, 28th ed)
A benign epithelial tumor with a glandular organization.
An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
The outer layer of the adrenal gland. It is derived from MESODERM and comprised of three zones (outer ZONA GLOMERULOSA, middle ZONA FASCICULATA, and inner ZONA RETICULARIS) with each producing various steroids preferentially, such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and ANDROSTENEDIONE. Adrenal cortex function is regulated by pituitary ADRENOCORTICOTROPIN.
An area occupying the most posterior aspect of the ABDOMINAL CAVITY. It is bounded laterally by the borders of the quadratus lumborum muscles and extends from the DIAPHRAGM to the brim of the true PELVIS, where it continues as the pelvic extraperitoneal space.
Radiation therapy used to treat the PITUITARY GLAND.
A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
A rare benign tumor of the adrenal gland, several centimeters in diameter, composed in varying proportions of adipose tissue, lymphocytes, and primitive myeloid cells, probably a developmental abnormality. (Dorland, 27th ed)
Symptom complex due to ACTH production by non-pituitary neoplasms.
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.
An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
Product of epinephrine O-methylation. It is a commonly occurring, pharmacologically and physiologically inactive metabolite of epinephrine.
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.
A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.
Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
Examinations that evaluate and monitor hormone production in the adrenal cortex.
A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE.
Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
A general class of ortho-dihydroxyphenylalkylamines derived from tyrosine.
A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.
Nucleus in the anterior part of the HYPOTHALAMUS.

Maternal adrenocortical hormones maintain the early development of pancreatic B cells in the fetal rat. (1/1561)

To investigate the effect of maternal adrenocortical hormones on the development of fetal pancreatic islet cells, pregnant rats were adrenalectomised on d 6 of gestation. On d 12-16 the growth patterns of fetal insulin-producing B cells, glucagon-producing A cells, and somatostatin-producing D cells were observed histometrically. Maternal adrenalectomy resulted in growth retardation of fetal B cells on d 12-15. Maternal corticosterone therapy prevented this retardation. Maternal adrenalectomy, however, did not affect the developmental patterns of A and D cells. By Western blotting and immunohistochemistry, glucocorticoid receptors were demonstrated to be present in the islet cells from d 12 to d 15. These results suggest that maternal adrenocortical hormones, glucocorticoids in particular, maintain the early development of fetal pancreatic B cells through their specific intracellular glucocorticoid receptor.  (+info)

Pharmacodynamic actions of (S)-2-[4,5-dihydro-5-propyl-2-(3H)-furylidene]-1,3-cyclopentanedione (oudenone). (2/1561)

The pharmacodynamic actions of (S)-2-[4,5-dihydro-5-propyl-2(3H)-furylidene]-1,3-cyclopentanedione (oudenone) were studied in both anesthetized animals and isolated organs. Oudenone (10--40 mg/kg i.v.) induced an initial rise in blood pressure followed by a prolonged hypotension in the anesthetized rats. In unanesthetized spontaneously hypertensive rats (SHR), oudenone (5--200 mg/kg p.o.) caused a dose-related decrease in the systolic blood pressure. The initial pressor effect was diminished by pretreatments with phentolamine, guanethidine, hexamethonium and was abolished in the pithed rats. In addition, intracisternal administrations of oudenone (100--600 mug/kg) showed a marked increase in blood pressure in the anesthetized rats, suggesting that the pressor effect may be due to centrally mediated actions. Oudenone, given intra-arterially into the femoral artery (400--800 mug/kg), caused a long-lasting vasodilation in anesthetized dogs. At a relatively high dose (40 mg/kg i.v.), oudenone antagonized all pressor responses to autonomic agents and central vagus nerve stimulation in anesthetized rats and dogs, however, oudenone showed no anti-cholinergic,-histaminergic, beta-adrenergic and adrenergic neuron blocking properties.  (+info)

Primary aldosteronism with aldosterone-producing adrenal adenoma in a pregnant woman. (3/1561)

A 30-year-old pregnant woman complained of muscle weakness at 29 weeks' gestation. She was hypertensive with severe hypokalemia. Lower plasma renin activity and higher aldosterone level than the normal values in pregnancy suggested primary aldosteronism. A cesarean delivery was performed at 31 weeks' gestation because of pulmonary congestion. The neonatal course was uncomplicated. The laparoscopic adrenalectomy for a 2.0-cm right adrenal adenoma resulted in normalizing of her blood pressure and serum potassium level. Although primary aldosteronism is rare, especially during pregnancy, it should be always considered as one of etiologies of hypertension in pregnancy.  (+info)

Activation of the adult mode of ovine growth hormone receptor gene expression by cortisol during late fetal development. (4/1561)

The developmental and tissue-specific regulation of growth hormone receptor (GHR) mRNA expression is complex and involves alternate leader exon usage. The transcript composition of hepatic GHR mRNA has therefore been determined in fetal sheep during late gestation and after experimental manipulation of fetal plasma cortisol levels by fetal adrenalectomy and exogenous cortisol infusion, using RNase protection assays and a riboprobe containing exons 1A, 2, and 3 of the ovine GHR gene. Expression of the adult liver-specific GHR mRNA transcript containing exon 1A was not detected earlier than 138 days of gestation (term 145 +/-2 days). Thereafter, expression of this leader exon increased and accounted for 25-30% of the total GHR mRNA in the fetal liver at term. Hepatic GHR mRNA derived from leader exons other than 1A was detectable at 97 days and increased in abundance toward term in parallel with the normal prepartum rise in fetal plasma cortisol. Abolition of this cortisol surge by fetal adrenalectomy prevented both the activation of exon 1A expression and the prepartum rise in GHR mRNA derived from the other leader exons in fetal ovine liver. Conversely, raising cortisol levels by exogenous infusion earlier in gestation prematurely activated exon 1A expression and enhanced the abundance of GHR mRNA transcripts derived from the other leader exons. Cortisol therefore appears to activate the adult mode of GHR gene expression in fetal ovine liver during late gestation. These observations have important implications for the maturation of the somatotrophic axis and for the onset of GH-dependent growth after birth.  (+info)

Glucocorticoid enhances interleukin-1-induced pressor response in freely moving rats through its effect on nitric oxide release. (5/1561)

We investigated whether changes in nitric oxide (NO) release might be responsible for the modulation by glucocorticoids of the pressor response to i.p. injection of interleukin-1beta (IL-1beta) in freely moving rats. In such rats, IL-1beta (10 microgram/kg) induced a biphasic pressor response, with a rise in the plasma concentration of NOx (NO2(-) and NO3(-): metabolites of NO) during the second phase. Systemic pretreatment with an exogenous glucocorticoid, dexamethasone (0.5 mg/kg), enhanced the second phase of the pressor response and completely suppressed the increase in plasma NOx. Treatment with Nomega-nitro-L-arginine methyl ester (L-NAME, a nonspecific NO synthase inhibitor), enhanced the pressor response while attenuating the increase in plasma NOx. After bilateral adrenalectomy, IL-1beta induced a smaller pressor response, but a larger increase in plasma NOx; dexamethasone reversed these changes. Our results suggest that endogenous NO moderates the pressor response to IL-1beta in freely moving rats, and that glucocorticoids enhance the IL-1beta-induced pressor response at least in part by reducing endogenous NO release.  (+info)

Endogenous glucocorticoids protect against cytokine-mediated lethality during viral infection. (6/1561)

Certain cytokines activate the hypothalamic-pituitary-adrenal axis for glucocorticoid release, and these hormones can protect against cytokine-mediated pathologies. However, endogenous activation of such a pathway has not been established during infections. A prominent glucocorticoid response peaks 36 h following murine CMV (MCMV) infection, coincident with circulating levels of the cytokines IL-12, IFN-gamma, TNF, and IL-6, and dependent on IL-6 for maximal release. These studies examined functions of the hormone induction. Mice rendered glucocorticoid deficient by adrenalectomy were more susceptible than intact mice to MCMV-induced lethality, and the increased sensitivity was reversed by hormone replacement. Lack of endogenous glucocorticoids resulted in increases in IL-12, IFN-gamma, TNF, and IL-6 production, as well as in mRNA expression for a wider range of cytokines, also including IL-1 alpha and IL-1 beta. Viral burdens did not increase, and actually decreased, in the livers of glucocorticoid-deficient mice. TNF, but not IFN-gamma, was required for increased lethality in the absence of endogenous hormone. These results conclusively demonstrate the importance of induced endogenous glucocorticoids in protection against life-threatening effects resulting from infection-elicited cytokine responses. Taken together with the dependence on induced IL-6, they document existence of an immune system-hypothalamic-pituitary-adrenal axis pathway for regulating endogenous responses to viral infections.  (+info)

Mechanisms underlying the anti-inflammatory actions of central corticotropin-releasing factor. (7/1561)

Immune activation of hypothalamic corticotropin-releasing factor (CRF) provides a negative feedback mechanism to modulate peripheral inflammatory responses. We investigated whether central CRF attenuates endothelial expression of intercellular adhesion molecule 1 (ICAM-1) and leukocyte recruitment during endotoxemia in rats and determined its mechanisms of action. As measured by intravital microscopy, lipopolysaccharide (LPS) induced a dose-dependent increase in leukocyte rolling, adhesion, and emigration in mesenteric venules, which was associated with upregulation of endothelial ICAM-1 expression. Intracisternal injection of CRF abrogated both the increased expression of ICAM-1 and leukocyte recruitment. Intravenous injection of the specific CRF receptor antagonist astressin did not modify leukocyte-endothelial cell interactions induced by a high dose of LPS but enhanced leukocyte adhesion induced by a low dose. Blockade of endogenous glucocorticoids but not alpha-melanocyte-stimulating hormone (alpha-MSH) receptors reversed the inhibitory action of CRF on leukocyte-endothelial cell interactions during endotoxemia. In conclusion, cerebral CRF blunts endothelial upregulation of ICAM-1 and attenuates the recruitment of leukocytes during endotoxemia. The anti-inflammatory effects of CRF are mediated by adrenocortical activation and additional mechanisms independent of alpha-MSH.  (+info)

Fetal rat adrenal steroidogenesis and steroid transfer to adrenalectomized mother. (8/1561)

On the 22nd day of gestation in rats, fetuses of acutely adrenalectomized mothers were injected subcutaneously with 0.43 muCi 4-14C-progesterone in 0.05 ml saline. Ten and 20 min after injection to fetuses, samples were taken to determine the 14C-progesterone metabolites in the plasma and adrenal glands. After extraction of the samples taken, the metabolites were separated by two-dimensional thin-layer chromatography and identified by autoradiography. 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone, corticosterone and 11beta-hydroxyprogesterone were identified in the plasma of injected fetuses, and, in far smaller amounts, in the plasma of their mothers. The plasma of noninjected fetuses also contained very small amounts of these corticoids. The fetal adrenal glands contained far smaller amounts of radioactive steroids than the fetal plasma did. The results obtained show that steroids of fetal origin can cross the placenta in and out, constituting evidence that the fetal adrenal glands are the only source of the plasma corticoids of their adrenalectomized mothers.  (+info)

AIM To analyze patient demographics, pathology, surgical procedure and outcome in initial 24 consecutive patients who underwent laparoscopic adrenalectomy in our department. METHODS Twenty four patients underwent laparoscopic adrenalectomy between September 2000 and August 2005. There were 12 males and 12 females with a mean age of 44.6 years (range 25-68 years). The indications for adrenalectomy were pheochromocytoma (13 patients), Cushings syndrome (5 patients), myelolipoma (2 patients), adrenal cyst (2 patients), aldosteronoma (1 patient) and adrenal incidentaloma (1 patient). Nineteen of our patients with functioning adrenal tumours were prepared preoperatively for periods ranging up to 2 weeks by the endocrinologist. All laparoscopic adrenalectomies were performed via lateral transperitoneal approach using standard four-port technique. Patients with pheochromocytoma and Cushings syndrome were monitored in the surgical intensive care unit during immediate postoperative period. The clinical and
Since 1992, transabdominal LA(laparoscopic adrenalectomy) has been a standard method of adrenalectomy. This traditional method has been used widely because this procedure provides wide view of the whole abdomen which is familiar to surgeons. But due to its unique location at retroperitoneum, adrenal is still not easy to approach. So various retroperitoneal approaches were designed and adjusted. Among those, PRA(posterior retroperitoneal adrenalectomy) has showed good outcomes in many institutes. PRA facilitates direct approach to kidney and adrenal gland, and so operative time can be shortened. But there has been no randomized controlled trial between these two methods.. Therefore, as experienced surgeons in both methods, we want to practice this study. ...
Introduction: Patients with subclinical Cushing s syndrome (SCS) present with increased cardiovascular morbidity and mortality, however, the beneficial effect of adrenalectomy on cardiovascular risk factors is uncertain.. Objective: Systematic meta-analysis to determine the effect of adrenalectomy vs conservative follow-up on cardiovascular risk factors in patients with adrenal tumors and SCS.. Methods: We searched 6 databases through July 2014. Pairs of independent reviewers selected studies and appraised the risk of bias. We included and extracted studies with at least five SCS patients with adrenal tumors undergoing adrenalectomy where outcomes of interest were measured before and after surgery. Outcomes of interest included hypertension, diabetes, dyslipidemia, and obesity. In majority of studies, improvement of an outcome was defined as postsurgical decrease in dose, number or discontinuation of medications used to treat the comorbidity.. Results: Definition of SCS was heterogeneous among ...
Laparoscopic Adrenalectomy Adrenalectomy is the surgical removal of all or part of an adrenal gland. The most common indicator for adrenalectomy is the presence of hormone-producing adrenal tumors. Prognosis is dependent upon individual medical history.
TY - JOUR. T1 - Corticosteroids and ACTH are not required for compensatory adrenal growth. AU - Engeland, W. C.. AU - Shinsako, J.. AU - Dallman, M. F.. PY - 1975. Y1 - 1975. N2 - The authors tested the hypothesis that unilateral adrenalectomy results in decreased glucocorticoid secretion, reflexly elevated ACTH secretion, and, consequently, compensatory adrenal growth. Plasma ACTH and corticosterone and right adrenal weight were measured during the first 10 days after left adrenalectomy or sham adrenalectomy in young male rats. There is a decrease in plasma corticosterone after unilateral adrenalectomy compared to sham adrenalectomy that persists for 1 h. ACTH is elevated only at 2 h after unilateral adrenalectomy compared to sham operated rats. Treatment with dexamethasone, shown to abolish the ACTH and corticosterone responses to laparotomy with intestinal traction, resulted in significantly increased adrenal weight after unilateral adrenalectomy by 6 h (wet or dry weight), and at 24 h. ...
TY - JOUR. T1 - Effects of adrenalectomy on CCD. T2 - Evidence for diferential response of two cell types. AU - Muto, S.. AU - Giebisch, G.. AU - Sansom, S.. PY - 1987/12/1. Y1 - 1987/12/1. N2 - Electrophysiological and chemical methods were used to determine the Na and K transport properties of the isolated cortical collecting duct (CCD) of control and adrenalectomized (ADX) rabbits. Net fluxes of Na (J(Na)) and K (-J(K)) in controls were 5.7 and 3.2 pmol·mm-1·min-1 and in ADX were 1.0 and 0.7 pmol·mm-1·min-1, respectively, similar to electrically determined rates. In separate experiments, blind impalement of cells from adrenal intact (group 1), ADX (group 2), and ADX rabbits treated with deoxycorticosterone (group 3) allowed identification of two distinct cell types, majority cells (MA) and minority cells (MI). In all groups, MA were distinguished from MI by a relatively high basolateral membrane potential (-V(b)), low apical membrane fractional resistance (FR(a)), and presence of apical ...
en] We investigated hemodynamics and plasma catecholamine concentrations in eight consecutive patients undergoing laparoscopic adrenalectomy for suspected pheochromocytoma. The same anesthesia protocol was used in all patients: a continuous infusion of sufentanil 0.5 microg x kg(-1) x h(-1) and isoflurane 0.4% (end-tidal) in 50% N2O/O2. Systolic arterial pressure was maintained between 120 and 160 mm Hg by adjusting an infusion of nicardipine, a calcium-channel blocker, while tachycardia (,100 bpm) was treated by 1-mg boluses of atenolol. Hemodynamics (thermodilution technique) and plasma catecholamine concentrations were measured before surgery, after the induction of anesthesia, after turning the patient to the lateral position, during pneumoperitoneum, during tumor manipulation, after adrenalectomy, and at the end of surgery. Two events resulted in significant catecholamine release: creation of the pneumoperitoneum and adrenal gland manipulation. As a consequence, a twofold increase in ...
Scherzer, A L.; Azar, H A.; Naujoks, G; and Williams, J, Effect of castration and adrenalectomy on the thymus and other lymphoid organs of mice. Abstr. (1963). Subject Strain Bibliography 1963. 923 ...
Semantic Scholar extracted view of [Endocrine factors and metabolism of thiamine. I. Effect of adrenalectomy on the uptake and phosphorylation of thiamine in the liver of (alloxan) diabetic and nondiabetic rats]]. by V. Cappelli et al.
Wilson, Ollie Bernice, The effect of adrenalectomy on the percent of hemolysis of erythrocytes in rats (1955). ETD Collection for AUC Robert W. Woodruff Library. 941 ...
View Poster. INTRODUCTION. Adrenalectomy is an operation performed by both urologists and general surgeons, however the majority are performed by general surgeons. We wanted to investigate whether there was a difference in outcomes based on surgical specialty performing the procedure. If no differences exist, an argument can be made that urologists should be doing more adrenalectomies. METHODS. The National Surgical Quality Improvement Project (NSQIP) Participant Use File (PUF) was queried to extract all cases of adrenalectomies performed during the years 2011-2015. The following two CPT codes were used: 60540 (open) and 60650 (laparoscopic). The data were stratified by surgical specialty who performed the adrenalectomy (urology or general surgery). Our outcomes of interest included post-surgical complications, reoperations, 30-day readmission, mortality, and hospital length of stay. RESULTS. A total of 3358 patients who underwent adrenalectomy were included, 3012 (90%) by a general surgeon and ...
Wiernik, P H., Effect of starvation of intact and adrenalectomized mice bearing lymphosarcoma p1798 on tumor regression and ribonuclease activity. (1970). Subject Strain Bibliography 1970. 1576 ...
Author(s): Seib, CD; Greenblatt, DY; Campbell, MJ; Shen, WT; Gosnell, JE; Clark, OH; Duh, QY | Abstract: Background Adrenalectomy is a complex procedure performed in many settings, with and without residents and fellows. Patients often ask, Will trainees be participating in my operation? and seek reassurance that their care will not be adversely affected. The purpose of this study was to determine the association between trainee participation and adrenalectomy perioperative outcomes. Study Design We performed a cohort study of patients who underwent adrenalectomy from the 2005 to 2011 American College of Surgeons NSQIP database. Trainee participation was classified as none, resident, or fellow, based on postgraduate year of the assisting surgeon. Associations between trainee participation and outcomes were determined via multivariate linear and logistic regression. Results Of 3,694 adrenalectomies, 732 (19.8%) were performed by an attending surgeon with no trainee, 2,315 (62.7%) involved a resident,
Hector R Romero, MD, Victoria Cerecedo, MD, Mauricio Sierra, MD, David Velazquez, MD PhD, Nicholas Williams, FRACS, Alexander P Heinze. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran. Background. Laparoscopic adrenalectomy (LA) is associated with several advantages over the open equivalent such as less postoperative pain, use of lesser dose of analgesics, decreased morbity, better cosmesis, an earlier return to work and regular activities, shorter hospital stay, reduced costs and greater patient satisfaction. However, the procedure has also been associated with limitations such as tumors larger than 6 cm, the diagnosis of pheochromocytoma or malignant lesions. There´s still ongoing debate on which is the appropriate limit for laparoscopic resection regarding tumor size. It is traditionally said that LA should be avoided if evidence of periadrenal infiltration is recognized preoperatively because invasion may compromise peripheral structures and because the capsule should ...
During the study period 79 patients met inclusion criteria with an average age of 54 years (range 21-83). Average ASA score was 3 and 66% of patients were female. A laparoscopic approach was employed in 95% with a conversion rate of 3.8%. Average operating room time was 127 minutes (range 50-307) and blood loss of 114ml (range 10-1600). Unilateral adrenalectomy was performed in all but 1 patient who underwent bilateral adrenalectomy for pheochromocytoma. The most common indication for surgery was primary hyperaldosteronism caused by an aldosterone producing adenoma (63%). Average postoperative length of stay was 2.4 days (range 1-15). Morbidity and mortality were 13% and 0 respectively. Tumor size was significantly higher in patients with nonfunctional tumors (4.4cm vs. 2.9cm, p,0.003 ...
This Laparoscopic Adrenalectomy consultation is part of a series of consultations with surgical specialists at the University of California, San Diego.
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1. The effects of replacing a 1% NaCl drinking solution with Na+-free water for 2 days on body weight and fluid and electrolyte balances were studied in adrenalectomized and sham-operated rats.. 2. Eight weeks after operation, after the animals had been drinking Na+-free water for 2 days, some adrenalectomized animals (about 75%; designated group 1) experienced body weight losses which were outside the 99% confidence limits for the sham-operated rats (- 9.2 to + 5.3 g) whereas the remainder (designated group 2) were indistinguishable from the controls.. 3. The body weight loss in group 1 was associated with negative fluid, Na+ and K+ balances. In group 2 rats, fluid balance was maintained as well as in the sham-operated rats, but their handling of Na+ and K+ was different.. 4. In a separate experiment, plasma aldosterone, corticosterone, catecholamine and solute concentrations were measured in adrenalectomized rats from groups 1 and 2 (selected on the basis of body weight loss whilst drinking ...
Patients with a mild form of Cushing syndrome, a metabolic disorder caused by adrenal tumors, demonstrate substantial clinical improvement after adrenalectomy.
The brain 5-HT (serotonin) system and circulating corticosteroids are in close interaction and both are implicated in the pathogenesis of affective disorders. The 5-HT1A receptor is thought to play a major role in this relationship. However, the recently cloned 5-HT7 receptor may also be involved, given its pharmacological similarities to the 5-HT1A receptor and its high expression in corticolimbic structures. Using in situ hybridization histochemistry, we have investigated 5-HT7 and 5-HT1A receptor mRNA expression in selected areas of the rat brain 7 days post-adrenalectomy. 5-HT7 receptor mRNA was increased in CA1 and CA3b after adrenalectomy, with no alterations in other hippocampal subfields or in retrosplenial cortex. Adrenalectomy was associated with a marked increase of 5-HT1A receptor mRNA in dentate gyrus, CA3 and CA2, but not in CA1, nor in the raphe. These data indicate that circulating adrenal steroids have a inhibitory role on the expression of hippocampal 5-HT7 receptors as well as 5-HT1A
N Engl J Med. 1981 Sep 3;305(10):545-51. Clinical Trial; Comparative Study; Randomized Controlled Trial; Research Support, U.S. Govt, P.H.S.
PM Stewart, J Corrie, JR Seckl, CRW Edwards, PL Padfield; A Rational Approach in Assessing the Need for Corticosteroid Replacement Therapy. Clin Sci (Lond) 1 January 1988; 74 (s18): 67P-68P. doi: https://doi.org/10.1042/cs074067Pc. Download citation file:. ...
Sixteen patients (eight males and eight females) underwent an adrenalectomy. The demographic composition of patients is summarized in Table 1. The patients mean age was 58.00± 11.34 years (range, 33-76 years). Three patients had undergone previous abdominal surgery; a 54-year-old female who underwent surgery due to an ectopic pregnancy 25 years ago, a 68-year-old female who underwent an appendectomy 50 years ago, and a 69-year-old female who underwent a hysterectomy with uterine leiomyoma 25 years ago. Regarding other comorbidities, 11 patients had hypertension, two of which had diabetes mellitus. Among patients with both hypertension and diabetes mellitus, one patient had a history of microvascular angina. Among the other patients with hypertension, one patient had angina pectoris, one had unstable angina, one had hypertrophic cardiomyopathy, and one had both chronic renal failure and cerebral infarction. Regarding the location of the tumors, the tumor was positioned on the right adrenal ...
One adrenal gland sits above each of your kidneys. Your two adrenal glands produce various hormones that help regulate your metabolism, immune system, blood pressure, blood sugar and other essential functions. If a noncancerous (benign) adrenal tumor or adrenal cancer is discovered, you may require an adrenalectomy (uh-dree-nul-EK-tuh-me) to remove the adrenal gland that has the tumor. If one adrenal gland is removed, the other takes over full function without the need for supplemental medications.
Adrenalectomy is surgery to remove all or part of one or both adrenal glands. The glands are above the kidneys. They make hormones that affect nearly every organ in the body. These hormones include adrenaline and cortisol. They do many things in the body. For example, they help control blood pressure. They help the body deal with stress. And they control the breakdown of fats and proteins in the liver. This surgery may be done to remove a tumour that is or isnt cancer. It also may be done for people with Cushings syndrome, a problem that causes too much cortisol in the body. It may be done to remove a tumour that makes too much adrenaline.. The surgery may be done through a single cut (incision). This is called open surgery. Or your child may have laparoscopic surgery. To do this, the doctor puts a lighted tube, or scope, and other tools through several small cuts.. If your child has laparoscopic surgery, he or she may be able to leave the hospital the next day. With open surgery, your child ...
Kirman I, Cekic V, Poltaratskaia N, et al. Plasma from patients undergoing major open surgery stimulates in vitro tumor growth: lower insulin-like growth factor binding protein 3 levels may, in part, account for this change. Surgery 2002;132:186-92.PubMedCrossRefGoogle Scholar ...
Learn more about Adrenalectomy -- Open Surgery at Grand Strand Medical Center DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
RIOS GONZALEZ, Emilio y MARTINEZ-PINEIRO LORENZO, Luís. Current role of lymphadenectomy and adrenalectomy in radical surgery for renal cancer. Actas Urol Esp [online]. 2009, vol.33, n.5, pp.562-568. ISSN 0210-4806.. Radical nephrectomy is the only curative treatment for renal cell cancer. Standard treatment includes ipsilateral adrenalectomy and lymph node dissection. In recent years, development of nephron-sparing surgery and early detection of small renal tumors has led to question this approach. The role of lymphadenectomy and adrenalectomy in surgical treatment of renal cancer is reviewed.. Palabras clave : Renal cell cancer; Lymphadenectomy; Adrenalectomy. ...
Os objetivos deste estudo foram avaliar os efeitos da pinealectomia, da adrenalectomia e da adrenalectomia mais pinealectomia na quantificação das células espermatogênicas de ratos. Assim, 32 ratos adultos Wistar com peso corporal médio de 331,7± 15,5g foram alocados em um dos seguintes tratamentos: (a) um grupo controle simulado, composto de nove animais; (b) dez animais pinealectomizados; (c) sete animais adrenalectomizados e (d) seis animais pinealectomizados+adrenalectomizados. Não foram encontradas diferenças significativas entre grupos para os seguintes parâmetros: pesos corporal, dos testículos, da próstata e das vesículas seminais, diâmetro dos túbulos seminíferos, número de células por corte transversal de túbulo seminífero (espermatócitos primários em paquíteno, espermátides arredondadas, células de Sertoli) e números de células espermáticas por célula de Sertoli (espermatócitos primários em paquíteno e espermátides arredondadas). Apesar do peso ...
Responses to angiotensin II were also depressed in adrenalectomized rats (Figure 2). Bolus angiotensin injections in isolated lungs produced typical transient
The administration of 3-methylcholanthrene to rats is accompanied by an increase in the incorporation of orotic acid-14C into the 45 S cytoplasmic particle in the liver. The elevation reaches a maximum at 15 hr after the injection of the polycyclic hydrocarbon and diminishes to control values by 36 hr. This effect was also observed in adrenalectomized animals, eliminating any role of the adrenal corticosteroids in the phenomenon. In addition, the turnover of 18 and 28 S ribosomal RNA in liver cytoplasm was elevated after administration of the polycyclic hydrocarbon. These results suggest that the synthesis of ribosomal constituents, in particular, ribosomal RNA, may play an important role in the induction phenomenon observed in liver after administration of 3-methylcholanthrene.. ...
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1. A human urinary thermostable glycoprotein (ABG-TsU) believed to be a homologue of the plasma aldosterone-binding globulin (ABG) was isolated and purified by differential ultra-filtration, ion-exchange chromatography and gel filtration to electrophoretic homogeneity; it showed a charge heterogeneity in electrofocussing.. 2. ABG-TsU was administered intraperitoneally to male rats in small daily doses (7 μg/day per rat). Sustained hypertension developed in 5-8 days.. 3. The treated rats showed no changes in plasma electrolytes, aldosterone or plasma renin activity; however, a significant increase in heart weight was observed.. 4. This hypertension appears to be adrenal dependent since it is prevented by bilateral adrenalectomy or administration of an aldosterone antagonist, but not by adrenalectomy when aldosterone is given concomitantly with ABG-TsU.. ...
Hydrocortisone (cortisol) is secreted by the adrenal cortex and has both glucocorticoid and mineralocorticoid effects. The term glucocorticoid derives...
Incidental findings of adrenal tumours,incidentalomas, occur in 1-5 % in the general population and 10-25 % of these patients will exhibit biochemical mild hypercortisolism. Although the patients do not have clinical signs of classical Cushings syndrome, they have an increased risk for hypertension, dyslipidemia, diabetes mellitus, osteoporosis and obesity.. The hypothesis of the study is, that surgery of the adrenal adenoma responsible for the increased secretion of cortisol, will in part cure or ameliorate the metabolic syndrome. ...
A 27 year old female G2 p1001 @ 7 week gestation was referred to our institution without obstetric services for persistent hypertension, palpitations, headache, lightheadedness, and fatigue and a family history of pheochromocytoma. Initial 24 hour urine revealed elevated dopamine, epinephrine and plasma norepinephrine levels. An abdominal MRI showed a 1.9 x 2.2 cm mass in the right adrenal gland along with several enlarged epigastric lymph nodes. The patient was started on phenoxybenzamine and labetalol. A laparoscopic adrenalectomy was planned at 15 week gestation pending stable hemodynamics. Surgery planned to have gastroenterology do an upper endoscopy with biopsy of the epigastric lymph nodes a week prior to her surgery, however, at the insistence of the obstetric anesthesiologist, the endoscopic procedure was scheduled at the time of the laparoscopy. Endocrinology was followed her vital signs on an outpatient basis prior to surgery, which required an increase in alpha and beta blockade due ...
possible extrathymic T cells (i.e. CD56þ T cells and CD57þ T Therefore, we used adrenalectomized mice in an attempt to cells) [9,10]. It was found that cell populations could be classified identify possible influences on the circadian rhythm [17]. These into two groups: one group with daytime rhythm includes granu- mice lost such circadian rhythms, implying some hormonal reg- locytes, monocytes, NK cells, extrathymic T cells, gd T cells, and ulation. However, because of impaired mobility, they also lost the CD8þ cells. The other, with night rhythm, includes conventional T variation of their physical activity round the clock. Changes in the and B cells, ab T cells, and CD4þ cells. It is well known that NK activity of the autonomic nervous system might affect leucocyte cells, extrathymic T cells and gd T cells are involved in natural subsets, some of them carrying adrenergic or cholinergic receptors immunity and are more primitive than conventional T (and ab T) [11,12]. There are many reports ...
History In my most recent post, which was a 2-year check-in since my MS diagnosis, I discussed a new health concern. In June of 2020, I had an ultrasound on my liver after some of my labs came back bad. The liver issue resolved on its own, but the ultrasound found a tumor on my…
History In my most recent post, which was a 2-year check-in since my MS diagnosis, I discussed a new health concern. In June of 2020, I had an ultrasound on my liver after some of my labs came back bad. The liver issue resolved on its own, but the ultrasound found a tumor on my…
It has repeatedly been shown that angiotensin II pretreatment enhances the subsequent hypoxic pressor responses in preparations perfused with artificial
1. When the suprarenal glands are removed from drakes they die after a mean interval of about 8 hours. They can be kept alive by the hourly injection of cortical extract. The amount of extract which must be injected varies at different times in the year, becoming much larger during the breeding season.. 2. The testes of the drake out of the breeding season weigh 1 to 4 grams. From January to May they increase in size to about 80 grams. During June they rapidly decline to the former small size. The curve of change in weight is closely parallel to the curve for the amount of cortical extract required after adrenalectomy, but the changes in the latter curve precede those in the former.. 3. After adrenalectomy castrated drakes require one third to one half of the amount of cortical extract necessary to keep normal birds alive during the breeding season. The increase in requirement of cortical extract during the breeding season is not due to the large amount of male hormone in the circulation, since ...
Nuchtern JG, London WB, Barnewolt CE, Naranjo A, McGrady PW, Geiger JD, Diller L, Schmidt ML, Maris JM, Cohn SL, Shamberger RC. A prospective study of expectant observation as primary therapy for neuroblastoma in young infants: a Childrens Oncology Group study. Ann Surg. 2012 Oct; 256(4):573-80 ...
We found no significant adaptation of the HPA axis to chronic FS, but did of glucose and other variables. A single exposure to FS did not cause long-term effects on the responsiveness of the HPA axis to the same stressor in contrast to that observed after IMO. We then studied the effects of single versus repeated exposure to IMO on the HPA response to the same stressor in both sham-operated and adrenalectomized rats maintained with corticosterone in their drinking saline (ADX+B). In sham rats, daily exposure to IMO had similar effects on the HPA axis that a previous single session. In contrast, in ADX+B rats, a reduction of the ACTH response to the stressor was observed in repeated but not single IMO rats. The present result suggest that the glucocorticoids are not mandatory for the development or adaptation of the HPA axis to chronic IMO, but they may be involved in the induction or expression of long-term effects of IMO on the HPA responsiveness to the same stressor. In order to better study ...
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Exacerbation of autoimmune thyroid dysfunction after unilateral adrenalectomy in patients with Cushings syndrome due to an adrenocortical adenoma
1. Marked hypertension was induced in adrenalectomized rats on a sodium-restricted intake by the administration of cortisone acetate; on a similar regimen, adrenalectomized rats receiving DCA failed to become hypertensive. 2. The incorporation of a liberal amount of sodium in the diet of adrenalectomized rats receiving cortisone acetate resulted in a lesser degree of hypertension; whereas on a similar regimen, DCA-injected animals became strikingly hypertensive, as has been previously reported. 3. The presence of hypertension in the cortisone acetate-treated rats was not associated with histological evidence of renal damage or serum electrolyte disturbance, such as was observed in hypertensive animals receiving DCA. 4. The hypertension in sodium-restricted normal rats receiving cortisone acetate was less striking than in similarly treated adrenalectomized animals. On a liberal sodium intake similar degrees of hypertension were noted in both intact and adrenalectomized groups. 5. To approximate ...
TY - JOUR. T1 - Laparoscopic Versus Open Adrenalectomy for Adrenocortical Carcinoma. T2 - Surgical and Oncologic Outcome in 152 Patients: Editorial Comment. AU - Cadeddu, Jeffrey A. PY - 2011. Y1 - 2011. UR - http://www.scopus.com/inward/record.url?scp=84937218160&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84937218160&partnerID=8YFLogxK. U2 - 10.1016/j.juro.2010.12.025. DO - 10.1016/j.juro.2010.12.025. M3 - Article. AN - SCOPUS:84937218160. VL - 185. SP - 1222. JO - Journal of Urology. JF - Journal of Urology. SN - 0022-5347. IS - 4. ER - ...
TY - JOUR. T1 - Hormonal mediation of the analgesia produced by food deprivation. AU - Hamm, Robert J.. AU - Knisely, Janet S.. AU - Watson, Ann. AU - Lyeth, Bruce G. AU - Bossut, D. F B. PY - 1985. Y1 - 1985. N2 - Research has demonstrated that a wide variety of environmental conditions are capable of producing analgesia. In the present experiment, the analgesia produced by 24 hr of food deprivation was examined following adrenalectomy, hypophysectomy, naltrexone (7 mg/kg), dexamethasone (0.4 mg/kg), or saline treatment. Results revealed that 24 hr of starvation elicited an analgesic response in the saline-treated and sham-operated groups. Naltrexone, dexamethasone, adrenalectomy, and hypophysectomy blocked the analgesia produced by food deprivation. The results demonstrate that 24 hr of food deprivation induced an opiate-mediated analgesic system that involves hormonal factors.. AB - Research has demonstrated that a wide variety of environmental conditions are capable of producing analgesia. ...
Fingerprint Dive into the research topics of Adrenal metastases from adenocarcinoma of the esophagogastric junction: Adrenalectomy and long-term survival. Together they form a unique fingerprint. ...
Kieran, K., Anderson, J. R., Dome, J. S., Ehrlich, P. F., Ritchey, M. L., Shamberger, R. C., . . . Davidoff, A. M. (2013). Is adrenalectomy necessary during unilateral nephrectomy for wilms tumor? A report from the childrens oncology group. Journal of Pediatric Surgery, 48(7), 1598-1603.. ...
adrenalectomy answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
Jen had Pituitary surgery by Dr. Shahinian 4/28/04, removed ACTH secreting corticotroph hyperplasia and prolactinoma. She was diagnosed by Dr. Theodore Friedman as cyclical pituitary Cushings. Her second Surgery 7/21/04 for infection resulted in neuralgia. She had a BLA in March 2006 as Corticol Hyperplasia returned and she now has possible Nelsons syndrome. Jen…
Ectopic adrenocorticotropic hormone (ACTH) production is an uncommon cause of Cushings syndrome and, rarely, the source can be a phaeochromocytoma. A 55-year-old man presented following an episode of presumed gastroenteritis with vomiting and general malaise. Further episodes of diarrhoea, joint pains and palpitations followed. On examination, he was hypertensive with no clinical features to suggest hypercortisolaemia. He was subsequently found to have raised plasma normetanephrines of 3.98 nmol/L (NR ,0.71) and metanephrines of 0.69 nmol/L (NR ,0.36). An adrenal CT showed a 3.8 cm right adrenal nodule, which was not MIBG-avid but was clinically and biochemically consistent with a phaeochromocytoma. He was started on alpha blockade and referred for right adrenalectomy. Four weeks later, on the day of admission for adrenalectomy, profound hypokalaemia was noted (serum potassium 2.0 mmol/L) with non-specific ST-segment ECG changes. He was also diagnosed with new-onset diabetes mellitus (capillary ...
Cardiac function was evaluated by ventricular function curves during the cardiovascular collapse observed in acute and chronic adrenal insufficiency. A progressive decline in peak cardiac work was observed in the acutely adrenalectomized cat (30% decrease at 1.8 hours and 50% at 3.5 hours after adrenalectomy). This impairment in cardiac work paralleled the decrease in mean arterial blood pressure which reached 50 mm Hg 3.5 hours after adrenalectomy. Cortisol and d-aldosterone, and the volume-expander, dextran, prevented a significant fall in mean arterial blood pressure and in peak cardiac work. When the mean arterial blood pressure of nonadrenalectomized cats was adjusted to follow the changes seen in adrenalectomized cats, a 49% depression in cardiac work resulted 3.5 hours after the initial decline in arterial blood pressure. The data suggest that the time course of the hypotension and presumed reduction in coronary perfusion pressure is sufficient to account for the large impairment in peak ...
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Laparoscopic adrenalectomy - a minimally invasive procedure that removes the adrenal glands through a tiny hole in the abdomen - can be safely performed in obese patients with Cushings syndrome, a retrospective study reports. The surgery resolved symptoms in 95% of cases, reducing cortisol level...
Genetic association studies hinge on definite clinical case definitions of the disease of interest. This is why more penetrant mutations were overrepresented in early multiple endocrine neoplasia 2 (MEN2) studies, whereas less penetrant mutations went underrepresented. Enrichment of genetic association studies with advanced disease may produce a flawed understanding of disease evolution, precipitating far-reaching surgical strategies like bilateral total adrenalectomy and 4-gland parathyroidectomy in MEN2. The insight into the natural course of the disease gleaned over the past 25 years caused a paradigm shift in MEN2: from the removal of target organs at the expense of greater operative morbidity to close biochemical surveillance and targeted resection of adrenal tumors and hyperplastic parathyroid glands ...
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CLINICAL HISTORY AND RADIOLOGY. The patient was a 52 year old male with a history of Cushings disease, initially diagnosed at the age of 18. At that time, his symptoms included increased weight, purple abdominal striae, diabetes mellitus, and polydipsia. He underwent a resection of a pituitary microadenoma at another hospital. However, due to persistently high cortisol levels following the surgery, he later underwent a bilateral adrenalectomy. Following the operation, he began hydrocortisone therapy, lost weight, and was able to maintain glucose control without diabetes medications. At the age of 32 his diabetes recurred, but he was able to maintain good glucose control up until age 51 at which time his HbA1C was greater than 7. He also had visual problems with significant reduction in right peripheral vision and moderate impairment in left. Testing revealed a greatly elevated serum ACTH at 5,082 pg/mL (normal is 9 - 46 pg/mL), but serum cortisol within normal limits 4 ug/dL. MRI scans found a ...
113.- ML.GALVE, V.CUERVAS-MONS, J.FIGUERAS, I.HERRERO, M.ATA, G.CLEMENTE, M.PRIETO, C.MARGARIT, A.BERNARDOS, F.CASAFONT. Incidence and outcome of the novo malignancies after liver transplantation. Transpl Proc 1999, 31:1275-1277. 114.- J. PUJOL, M. VILADRICH, A. RAFECAS, L. LLADÓ, A. GARCÍA-BARRASA, J. FIGUERAS, E. JAURRIETA. Laparoscopic adrenalectomy: review of initial 30 cases. Surgical Endoscopy 1999; 13-488-492. 115.- P.PARRILLA, F. SÁNCHEZ BUENO, J. FIGUERAS, E. JAURRIETA, J. MIR, C. MARGARIT, J. LÁZARO, L. HERRERA, M. GÓMEZ FLEITAS, E. VARÓ, E. VICENTE, R. ROBLES, P. RAMIREZ. Analysis of the complication of the piggy-back technique in 1.112 liver transplants. Transplantation 1999; 67:1214-1217.. 116.- A. DALMAU, A. SABATÉ, F. ACOSTA, L. GARCÍA HUETE, M. KOO, M. RECHE, A. RAFECAS, J. FIGUERAS, E. JAURRIETA. Comparative study of antifibrinolytic drugs in orthotopic liver transplantation. Transp Proc 1999; 31:2361-2362. 117.- D. PARÉS, J. FIGUERAS, A. RAFECAS, J. FABREGAT, J. ...
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Tumors of the adrenal cortex are reported in 2% of all autopsies, with the most common lesion being a benign adenoma (see the first image below). The common major pathologic entities of the adrenal gland that require surgical intervention are primary hyperaldosteronism (ie, Conn syndrome, see the second image below), Cushing syndrome, pheochr...
Learn about benign adrenal tumors and adrenal cancer treatment, such as an adrenalectomy, by endocrine surgeons at Brigham and Womens Hospital.
The Aldosteronoma Resolution Score (ARS) is currently the most accurate prediction model for complete resolution of hypertension after adrenalectomy, taking into account 4 preoperative clinical parame... more
Researchers from Germany looked at the clinical parameters that predict hypertension resolution following laparascopic adrenalectomy.
High levels of estrogen causes an increase in levels of cortisol-binding globulin which - you guessed it - binds cortisol in the blood. The amount of free cortisol available to enter the cell membranes and activate receptors inside the cell is now
TY - JOUR. T1 - Catecholamine-glucocorticoid interactions during surgical stress. AU - Udelsman, Robert. AU - Goldstein, David S.. AU - Loriaux, D. Lynn. AU - Chrousos, George P.. PY - 1987/12. Y1 - 1987/12. N2 - The stress response involves activation of the hypothalamic-pituitary adrenal axis and the sympathetic nervous system. To study the relative contributions of glucocorticoids, epinephrine, norepinephrine, and dopamine to homeostasis, we examined the effects of cortisol and epinephrine deficiency on the norepinephrine and dopamine responses to surgical stress in nonhuman primates. Adult male cynomolgus monkeys (n = 7-8/group)underwent bilateral or sham adrenalectomy and were maintained for 4 months on physiologic glucocorticoid (hydrocortisone phosphate, 32 mg/M2/day) and mineralocorticoid (DOCA pivalate, 1 mg/day) replacement, or placebo injections, respestively. The adrenalectomized monkeys were then stratified into three groups receiving subphysiologic (× 1 10), physiologic (×1), or ...
The effect of alterations in extracellular fluid volume (ECV) and solute concentration on excretion of urinary kallikrein was examined in conscious Sprague-Dawley rats. Animals were given infusions of either dextrose and water, saline, or albumin according to a variety of protocols. These were designed to evaluate possible relationships between excretion of kallikrein, volume, sodium, and potassium. A reproducible pattern of kallikrein excretion was noted in all volume expanded groups. This consisted of a short lived increase during the initial hour of expansion with a subsequent fall to lower levels than baseline and a gradual recovery. To define the role of aldosterone in these studies, an adrenalectomized group and a group of appropriately prepared sham controls were expanded with saline. Adrenalectomy did not effect this pattern. We postulate a tubular washout phenomenon as the etiology of these observations. Results of these studies fail to demonstrate a consistent relationship between ...
The adrenal glands are part of the endocrine system, which regulates hormone levels in the body. They are small, pyramid-shaped glands that rest on th...
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Brisbane adrenal surgeon Dr David Wilkinson specialises in adrenal conditions which are explained here: adrenalectomy - removal of an adrenal gland indicated in two main situations ...
Related Articles Minimally Invasive Adrenalectomy: Technical Aspects of the Laparoscopic and the Robotic Approach. Chirurgia (Bucur). 2020 Jan-Feb;115(1):80-88 Authors: Makkai-Popa ST, Pascotto B, Arru L ...
A list of 15 letter words that start with Ad in the enable censored word list. 11 words: adenocarcinomas adenohypophyses adenohypophysis adjustabilities administrations admirablenesses admissibilities adrenalectomies adventurousness adversarinesses advisablenesses...
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As part of this work, Broster devised a new method for adrenalectomy which he reported in a 1932 paper. At the time, operations ... Removal of the larger adrenal gland (an adrenalectomy) revealed the cause of its enlargement was not a tumour but hyperplasia. ... the results of unilateral adrenalectomy". British Journal of Surgery. 19 (76): 557-570. doi:10.1002/bjs.1800197606. S2CID ...
Shen WT, Lee J, Kebebew E, Clark OH, Duh QY (August 2006). "Selective use of steroid replacement after adrenalectomy: lessons ... Lee JE, Curley SA, Gagel RF, Evans DB, Hickey RC (December 1996). "Cortical-sparing adrenalectomy for patients with bilateral ... Typically, complete or total adrenalectomy is performed; however, a technique referred to as "cortical-sparing" can leave a ... Adrenal Insufficiency: Following a bilateral adrenalectomy (left and right), the patient is no longer capable of secreting the ...
Nursing care after adrenalectomy or hypophysectomy. The American Journal of Nursing, 62(4), 84-86. Lubic, R.W. (1969). The ...
Adrenalectomy is the treatment of choice. Metyrapone may also be used for treatment. McCune-Albright syndrome is estimated to ...
Anías-Calderón, José; Verdugo-Díaz, Leticia; Drucker-Colín, René (2004). "Adrenalectomy and dexamethasone replacement on ...
"Trends in adrenalectomy: a recent national review". Surg Endosc. 24 (10): 2518-2526. doi:10.1007/s00464-010-0996-z. PMID ...
Nelson DH, Meakin JW, Thorn GW (March 1960). "ACTH-producing pituitary tumors following adrenalectomy for Cushing's syndrome". ... Aggarwal S, Yadav K, Sharma AP, Sethi V (June 2013). "Laparoscopic bilateral transperitoneal adrenalectomy for Cushing syndrome ...
The effect of adrenalectomy upon the total metabolism of the cat. The metabolic effect of adrenalectomy upon the urethanized ... Aub, Joseph C., Forman, Jonathan, & Bright, E. M. (1922). The effect of adrenalectomy upon the total metabolism of the cat. Am ... Aub, J. C., Bright, E. M., & Forman, J. (1922). The metabolic effect of adrenalectomy upon the urethanized cat. Am. J. Physiol ...
Role of adrenalectomy and adrenal-cortical hormones in oxygen poisoning. American Journal of Physiology. Legacy Content, 178(2 ...
At the point where abdominal CT scanning and pituitary fossa MRI show no clear abnormalities, adrenalectomy may be performed. ... The most common treatment for PPNAD is bilateral laparoscopic adrenalectomy; the process by which both adrenal glands are ...
Adrenalectomy is the removal of one or both adrenal glands. Apicoectomy is the surgical removal of tooth's root tip. ...
"Livedo Reticularis in a Patient with Pheochromocytoma Resolving After Adrenalectomy". The Journal of Clinical Endocrinology & ...
Unilateral adrenalectomy is the treatment of choice for unilateral PHA. Potential complications include hemorrhage and ...
Yukimura Y, Bray GA (1978). "Effects of adrenalectomy on body weight and the size and number of fat cells in the Zucker (fatty ... Obesity in rats was significantly reduced by adrenalectomy or hypophysectomy. The role of neuropeptide Y has gained substantial ...
In addition, adrenalectomies are used to diagnose the lesion and sometimes relieve pain. Because pseudocysts are closely ... an adrenalectomy or laproscopy may be used. Zadik, Yehuda; Aktaş, Alper; Drucker, Scott; Nitzan, Dorrit W. (2012). "Aneurysmal ...
Following adrenalectomy, adrenaline disappears below the detection limit in the bloodstream. Pharmacological doses of ... Low or absent concentrations of adrenaline can be seen in autonomic neuropathy or following adrenalectomy. Failure of the ...
... is also referred to as post adrenalectomy syndrome, a possible result of adrenalectomy performed for ... After a bilateral adrenalectomy is performed cortisol levels are no longer normal. This increases CRH production because it is ... The onset of the disease can occur up to 24 years after a bilateral adrenalectomy has been performed, with an average of up to ... A preventative measure that can be utilized is prophylactic radiotherapy when a bilateral adrenalectomy is being performed in ...
Comparison of tissue accumulation of hexoestrol with response to bilateral adrenalectomy and oophorectomy". Lancet. 2 (7206): ...
He was the first surgeon to perform an adrenalectomy to treat advanced malignancy. Brewer married Marjorie Hirst, who he met ...
Other robotic surgery he has been involved in include nephroureterectomy, pyeloplasty and adrenalectomy. He teaches robotics ...
Suspicious adrenal masses or those ≥4 cm are recommended for complete removal by adrenalectomy. Masses 1 cm (unless the TSH is ...
In people with a single benign tumor (adenoma), surgical removal (adrenalectomy) may be curative. This is usually performed ...
Studies have shown that corticosterone treatment and adrenalectomy reduces or upregulated hippocampal BDNF expression. ...
"The level and phosphorylation of Hsp70 in the rat liver cytosol after adrenalectomy and hyperthermia". Cell Biology ...
Galante M, McCorkle HJ: Clinical evaluation of bilateral adrenalectomy and oophorectomy for advanced mammary carcinoma. Am J ...
She was managed successfully with right adrenalectomy, and the tumor histology was consistent with adrenal oncocytoma. Santos- ...
However, even after adrenalectomy, HSD2 neurons become activated by sodium deprivation, proving that MR activation is not ... All of these conditions, with the exception of adrenalectomy, cause a large elevation of circulating aldosterone. ... and adrenalectomy-also activate HSD2 neurons, although none do so to as great an extent as simply removing sodium from the diet ...
Bilateral adrenalectomy is another treatment that provides immediate reduction of cortisol level and control of ... is progression of Nelson's syndrome which is caused by enhance level of tumor growth and ACTH secretion post adrenalectomy in 8 ...
Rees, SL; Panesar, S; Steiner, M; Fleming, AS (Mar 2006). "The effects of adrenalectomy and corticosterone replacement on ...
Adrenalectomy could be either unilateral or bilateral, the surgical removal of namely one or both adrenal glands. Non-operative ... It treats the hemorrhage by adrenal repair or adrenalectomy, depending on the extent of injury, the viability of residual ...
Single Incision Robotic Adrenalectomy. Lawrence E Tabone, MD, Chan Park, MD, Dana Portenier, MD ... Our objective was to expand this technology and technique for single incision robotic adrenalectomy. We believe this to be the ... We were able to easily complete a single incision robotic adrenalectomy without significant alterations in the standard robotic ... We used the da Vinci Surgical System to perform a robotic adrenalectomy with this single incision platform. ...
The aim is to report the authors experience in laparoscopic left adrenalectomy with an alternative transperitoneal ... The safety and efficacy of laparoscopic transperitoneal lateral adrenalectomy and retroperitoneoscopic adrenalectomy have been ... Laparoscopic adrenalectomy compared to open adrenalectomy for benign adrenal neoplasms. J Am Coll Surg. 1996 Jul;183(1):1-10.. ... Posterior retroperitoneoscopic adrenalectomy is a safe and effective alternative to transabdominal laparoscopic adrenalectomy ...
Preoperative cross-sectional imaging can prevent unnecessary adrenalectomy in patients undergoing radical nephrectomy for RCC. ... ATLANTA-Preoperative cross-sectional imaging can prevent unnecessary adrenalectomy in patients undergoing radical nephrectomy ... and colleagues studied 123 patients with documented ipsilateral adrenalectomy. Six patients (4.8%) had adrenal involvement and ...
... we have performed LESS retroperitoneal adrenalectomies for seven consecutive patients (4 men and 3 women, ages 33-54 years) ... Single-access retroperitoneoscopic adrenalectomy (SARA) versus conventional retroperitoneoscopic adrenalectomy (CORA): a case- ... Surg Clin North Am 76:523-537 PubMedCrossRef Gagner M (1996) Laparoscopic adrenalectomy. Surg Clin North Am 76:523-537 PubMed ... Zurück zum Zitat Castellucci SA, Curcillo PG, Ginsberg PC, Saba SC, Jaffe JS, Harmon JD (2008) Single-port access adrenalectomy ...
Seymour, Patricia A., "The Effect of Adrenalectomy and Stress on Autoanalgesia in the Rat" (1981). Open Access Masters Theses. ...
... - /ədrinəˈlɛktəmi/ (say uhdreenuh lektuhmee) noun (plural adrenalectomies) the removal of one or both adrenal ... Adrenalectomy is the surgical removal of one or both (bilateral adrenalectomy) adrenal glands. It is usually advised for… … ... adrenalectomy - ad·re·nal·ec·to·my (ə drē nə lĕkʹtə mē) n. pl. ad·re·nal·ec·to·mies Surgical excision of one or both of the ... adrenalectomy - Removal of one or both adrenal glands. [adrenal + G. ektome, excision] * * * ad·re·nal·ec·to·my tə mē n, pl ...
Blood spotting from the incisions is expected and not cause for alarm. All stitches will dissolve on their own. The incisions are usually covered with a purplish skin glue that will peel off on its own after 1-2 weeks ...
Well start with the good news about the adrenalectomy first. The mass on my adrenal gland was not cancer nor was it a ... I say semi-normal because some things started happening after the adrenalectomy that has made us all very happy. Let me give ...
Learn more about laparoscopic and open adrenalectomy for adrenal gland tumors. ... An adrenalectomy is surgery to remove your left and/or right adrenal gland when you have a tumor on your adrenal gland that is ... Open adrenalectomy. A large abdominal incision is used when there is a diagnosis or a strong suspicion of adrenal cancer before ... After unilateral adrenalectomy (most common): If you have one adrenal gland removed there is no need to take supplements. Your ...
Note: The adrenalectomy group was divided into APA and APN groups according to the adrenal pathology. Asterisks indicate ... Table 2. Clinical and biochemical cure in the adrenalectomy group according to the PASO criteria 23 Variable (reference range, ... The strengths of our study are its prospective design, long-term follow-up of the adrenalectomy group, use of CYP11B1 and ... We could further characterize the adrenalectomy group to those with CYP11B2-positive APA and those with APN, that is, patients ...
Anesthetic management of left adrenal myelolipoma posted for left adrenalectomy. Author: Dr. Vijaykumar, T. K., Dr. ... posted for left adrenalectomy. The physical examination was unremarkable, Laboratory investigations revealed the non- ...
Author information Abstract OBJECTIVE: Beneficial effects of adrenalectomy on cardiovascular risk factors in patients with ... 24-hour urinary free cortisol 40 Days abstract ACTH Addisons disease adenoma adrenal adrenalectomy adrenal glands adrenal ... Beneficial effects of adrenalectomy on cardiovascular risk factors in patients with Subclinical Cushing Syndrome (SCS) are ... Filed under: adrenal, Cushings , Tagged: abstract, adrenal tumor, adrenalectomy, cardiovascular, subclinical Cushings ...
Adrenalectomy specimen containing pheochromocytoma. Non-neoplastic adrenal cortex (yellow) surrounds a small tan-red tumor in ... Unilateral subtotal adrenalectomy for pheochromocytoma in multiple endocrine neoplasia type 2 patients: a feasible surgical ... Pheochromocytoma does not increase risk in laparoscopic adrenalectomy. Surg Endosc. 2010 Nov. 24(11):2760-4. [QxMD MEDLINE Link ... This agent is often used immediately before or during adrenalectomy to prevent or control paroxysmal hypertension resulting ...
Nephron sparing surgery and cortical sparing adrenalectomy are the treatment of choice for multifocal RCC and pheochromocytomas ... Three underwent cortical sparing and seven total adrenalectomies; 13 patients underwent nephron sparing surgery (NSS), of which ... Outcomes of nephron sparing surgery and cortical sparing adrenalectomy in the management of Von Hippel-Lindau syndrome. Access ...
Laparoscopic Left Adrenalectomy Technique. 03:00 , 6665 views Watch VIDEO. 4678 views ...
It is treated by bilateral adrenalectomy. We present an unusual case where this condition was unilateral and was diagnosed as ...
Adrenalectomy for adrenal cortical carcinoma. Adrenalectomy for ≥6cm masses. Retroperitoneal lymph node dissection ... Adrenalectomy for benign pathology. Radical nephrectomy for T1-T3a renal cell carcinoma. Simple nephrectomy for benign disease* ... 1 2 3 4 For benign adrenal tumors, including pheochromocytoma,7 laparoscopic adrenalectomy is the standard of care.5 6 7 8 9 ... Laparoscopic adrenalectomy: a new standard of care. Annals of Surg 1997 May; 225 (5): 495-501. ...
Laparoscopic Nissen and Nephrectomy/Adrenalectomy - Animate Lab. *Laparoscopic Bowel Resection and Billroth II - Animate Lab ...
In a partial adrenalectomy, this can lead to venous congestion and gland compromise.[52] In a patient with an effective ... In a total adrenalectomy, the adrenal vein is generally divided early to limit catecholamine release with gland mobilization. ... Leaving residual cancer behind is a concern with a partial adrenalectomy in patients with a malignant PHEO; however, in the VHL ... Vargas HI, Kavoussi LR, Bartlett DL, et al.: Laparoscopic adrenalectomy: a new standard of care. Urology 49 (5): 673-8, 1997. [ ...
Adrenalectomy. *Bladder Augmentation. *Bladder Cuff Excision *Bladder Neck Suspension. *Mitrofanaoff (Appendicovesicostomy). * ...
Mastectomy, Breast reduction, Minimally invasive parathyroidectomy, Laparoscopic surgery, Adrenalectomy, Pancreatic enu... ...
Adrenalectomy *Excision of an adrenal gland. 74. Surgical Therapeutic Interventions*Diabetes Treatment ...
Adrenalectomy. Steven Z. Rubin, Marcos Bettolli. 58. Nephroureterectomy. Benno M. Ure, Martin L. Metzelder. 59. Transabdominal ...
Open Adrenalectomy -- 6. Laparoscopic Adrenalectomy: Transperitoneal Approach -- 7. Laparoscopic Adrenalectomy: Retroperitoneal ...
Adrenalectomy. ESOPHAGUS Surgery:. *Diverticula resection. *Heller Myotomy (for Achalasia). *Nissen fundoplication (GERD, ...
Assessment and management of adrenal tumours, including endoscopic retroperitoneal adrenalectomy. Commitment to excellence: ...
1998) Basolateral amygdala lesions block the disruptive effects of long-term adrenalectomy on spatial memory. Neuroscience 84: ... 1990) Effect of adrenalectomy and demedullation on the stress-induced impairment of long-term potentiation. Neuroendocrinology ... via adrenalectomy) and high (via exogenous administration) levels of corticosterone impairing LTP. In addition, corticosterone ...
Almost five months later, he undergoes adrenalectomy. Six months later to the day, he receives an autologous bone marrow ...
  • In patients with bilateral pheochromocytomas, cortical-sparing adrenalectomy should be considered if it is technically feasible. (medscape.com)
  • IMSEAR at SEARO: Successful pregnancy following bilateral adrenalectomy for Cushing's syndrome. (who.int)
  • Thus two-step bilateral adrenalectomy was planned. (nel.edu)
  • however, bilateral adrenalectomy may expose the patient to novel endocrinological complications, such as the development of iatrogenic Addison's disease. (spandidos-publications.com)
  • Therefore, minimally invasive surgical procedures and partial adrenalectomy, in addition to radical nephrectomy, should be the preferred treatment strategy for bilateral synchronous adrenal metastasis from RCC. (spandidos-publications.com)
  • I note that depression occurs in patients with hyperadrenalism and may be ameliorated by bilateral adrenalectomy . (bmj.com)
  • A modified rotarod technique is used to determine if dietary deficiencies in pyridoxine (65236) or thiamine (59438), bilateral adrenalectomy or cortisol (50237) treatment and pretreatment with microsomal enzyme inducers (DDT (50293) or phenobarbital (57307)) would modify the course of onset and recovery from functional acrylamide neuropathy in rats. (cdc.gov)
  • It is recognized that bilateral adrenalectomy (ADX) enhances hypothalamic CRHergic function and reduces appetite. (conicet.gov.ar)
  • Patients who have undergone bilateral adrenalectomy will need to have replacement of adrenal function with cortisol and mineralocorticoid. (uihc.org)
  • They underwent laparoscopic bilateral adrenalectomy. (jofem.org)
  • A paradoxical rise of urinary free cortisol (UFC) in response to dexamethasone is an early and specific laboratory marker of the disorder, allowing timely bilateral adrenalectomy which may not only prevent severe complications of hypercortisolism, but may also preclude the development of adrenocortical carcinoma. (jofem.org)
  • Corticosteroid feedback control of ACTH secretion: rapid effects of bilateral adrenalectomy on plasma ACTH in the rat. (umich.edu)
  • Despite a multi-therapeutic approach, including the administration of multiple courses of chemotherapy, hypo-cortisolemic agents, somatostatin analogues, as well as the performance of bilateral adrenal vein embolization followed by bilateral adrenalectomy, patient's condition progressively deteriorated and she died nine months after the diagnosis of NEC due to liver failure. (nel.edu)
  • Among these, one patient underwent a partial nephrectomy and subsequent contralateral radical nephrectomy, and another patient underwent simultaneous bilateral adrenalectomies. (canjurol.com)
  • One potential risk or bilateral adrenalectomy is the development of Nelson's Syndrome - an aggressive ACTH-secreting pituitary adenoma. (pacificneuroscienceinstitute.org)
  • For more information, please go to Open Adrenalectomy , Laparoscopic Left Adrenalectomy , and Laparoscopic Right Adrenalectomy . (medscape.com)
  • She had a previous history of left radical nephrectomy with left adrenalectomy 1.5 years prior to hospitalization, followed by radiation therapy to the kidney area as treatment for hypernephroma. (who.int)
  • Consequently, right radical nephrectomy, right partial adrenalectomy (with frozen section examination) and left adrenalectomy were planned. (spandidos-publications.com)
  • As a result, laparoscopic left adrenalectomy was performed. (bmj.com)
  • In laparoscopic left adrenalectomy, the patient would be lying on his/her right side. (medicalonlinedirectory.com)
  • Laparoscopic hand-assisted left adrenalectomy and umbilical hernia repair. (mtsamples.com)
  • [ 1 ] open adrenalectomy still plays an important role in the armamentarium of adrenal surgeons. (medscape.com)
  • In addition, open adrenalectomy is the treatment of choice for patients in whom laparoscopic surgery is contraindicated. (medscape.com)
  • When patient and tumor characteristics are appropriate, minimally invasive adrenalectomy is recommended over open adrenalectomy. (medscape.com)
  • Open adrenalectomy is performed when the tumour is large in size. (medanta.org)
  • Surgical options for open adrenalectomy. (shengsci.com)
  • Laparoendoscopic single-site (LESS) adrenalectomy has become a feasible choice for adrenal lesions and can substitute for conventional open adrenalectomy. (e-urol-sci.com)
  • For the malignant tumors of the adrenal glands, open adrenalectomy may be preferred. (medicalonlinedirectory.com)
  • However, an alternative approach is possible called retroperitoneoscopic adrenalectomy (PRA), where the adrenal glands are reached through small cuts made in the back. (wikipedia.org)
  • Masha Livhits, MD, performing retroperitoneoscopic adrenalectomy. (uclahealth.org)
  • Drs. Masha Livhits & Kyle Zanocco, UCLA Endocrine Surgery, performing retroperitoneoscopic adrenalectomy. (uclahealth.org)
  • Data on 80 patients who underwent radical or partial nephrectomy, nephroureterectomy or adrenalectomy through 82 flank incisions with eleventh rib resection were collected and analyzed retrospectively. (canjurol.com)
  • Eighty-two patients who underwent laparoscopic adrenalectomy for pheochromocytoma between July 2002 and February 2020 were examined. (medscape.com)
  • We investigated the risk factors for HDI during laparoscopic adrenalectomy for pheochromocytoma. (medscape.com)
  • Surgeons and anaesthesiologists need to be aware of the risk of HDI and its prolongation during laparoscopic adrenalectomy for pheochromocytoma for DM patients. (medscape.com)
  • [ 4 ] reported all-cause and cardiovascular morbidity rates of 16% and 4.8%, respectively, after laparoscopic adrenalectomy (LA) for pheochromocytoma. (medscape.com)
  • A minimally invasive adrenalectomy for a metabolically active tumor such as a pheochromocytoma highlights such a trial. (auanet.org)
  • Our goal is to provide a methodical and reproducible template for performing a right side adrenalectomy for a suspected pheochromocytoma. (auanet.org)
  • Dr Rafael Coelho will show Robotic adrenalectomy for Pheochromocytoma. (vattikutifoundation.com)
  • We describe this event following adrenalectomy for pheochromocytoma in a patient affected by neurofibromatosis. (onlinejets.org)
  • These hormone-producing tumors may need adrenalectomy. (wikipedia.org)
  • Additionally, adrenal tumors that are larger than 4 centimeters in size, regardless of whether they produce hormones, also require adrenalectomy due to increased risk of adrenal cancer. (wikipedia.org)
  • However benign (hormone active or not) adrenal tumors mostly underwent minimally invasive adrenalectomy (Laparoscopic, robotic or Single incision Laparoscopic). (wellht.com)
  • Laparoscopic adrenalectomy for adrenal tumors: A 21-year single-institution experience. (medscape.com)
  • Conclusions: The preliminary results show that LESS retroperitoneal adrenalectomy is a safe and feasible procedure for functional adrenal tumors using standard laparoscopic instruments. (elsevier.com)
  • This report shares our surgical experience and describes the characteristics of adrenal tumors after LESS retroperitoneal adrenalectomy. (e-urol-sci.com)
  • Specialized surgical procedures available include pancreatic resection of endocrine tumors and adrenalectomy (removal of the adrenal gland), when indicated. (southnassau.org)
  • His advanced surgical expertise includes minimally invasive parathyroidectomy and thyroidectomy, central and modified radical neck dissection, single incision laparoscopic adrenalectomy and laparoscopic resection of endocrine pancreas tumors. (aasurg.org)
  • Laparoscopic adrenalectomy (LA) is considered as a best approach for the treatment for adrenal tumors. (sch.ac.kr)
  • We present a robot-assisted laparoscopic right adrenalectomy, highlighting the key steps to performing the procedure safely and efficiently. (auanet.org)
  • Robotic right adrenalectomy is safe and efficient. (auanet.org)
  • I performed exploratory coeliotomy, lysis of adhesions, side-to-side enteroenterostomy bypassing the grossly abnormal irradiated bowel, and right adrenalectomy. (who.int)
  • A clinical diagnosis of adrenal myelolipoma was made and right adrenalectomy was performed. (indianjurol.com)
  • Laparoscopic adrenalectomy is recommended for patients with unilateral primary aldosteronism (PA). (medscape.com)
  • INTRODUCTION: Subtype classification method is essential when considering adrenalectomy as a possible treatment for primary aldosteronism. (tuni.fi)
  • Predictors of successful outcome after adrenalectomy for primary aldosteronism. (cdc.gov)
  • Adrenalectomy can also be done to remove a cancerous tumor of the adrenal glands, or cancer that has spread from another location, such as the kidney or lung. (wikipedia.org)
  • Adrenalectomy in Delhi involves the removal of a gland located above the kidney called adrenal gland, being rare to have to remove both(right and left). (drmohitjain.com)
  • Is Laparoendoscopic Single-Site Adrenalectomy a Feasible Alternative in Treating Aldosterone-Producing Adenoma? (elsevier.com)
  • To compare laparoendoscopic single-site (LESS) and conventional multiport adrenalectomy in patients with aldosterone-producing adenoma (APA). (elsevier.com)
  • 深入研究「Is Laparoendoscopic Single-Site Adrenalectomy a Feasible Alternative in Treating Aldosterone-Producing Adenoma? (elsevier.com)
  • Background: This study aimed to evaluate laparoendoscopic single-site (LESS) adrenalectomy via the retroperitoneal approach using the Alexis wound retractor with standard laparoscopic instrumentation. (elsevier.com)
  • Adrenal surgery has a long history, with the first planned adrenalectomy performed in 1914 by Sargent. (medscape.com)
  • For decades, little change to adrenal surgery was seen, until the first laparoscopic adrenalectomy was described by Gagner in 1992. (medscape.com)
  • Adrenalectomy is not performed on those who have severe coagulopathy or whose heart and lungs are too weak to undergo surgery. (wikipedia.org)
  • An absolute contraindication (a reason not to do the surgery under any situation) for adrenalectomy are patients who are generally unsuited to surgery: having severe coagulopathy and poor cardiopulmonary performance due to the stress to the body that surgery will produce. (wikipedia.org)
  • Guidelines for adrenalectomy were published in October 2022 by the American Association of Endocrine Surgeons (AAES) in JAMA Surgery . (medscape.com)
  • The benefit of laparoscopic adrenalectomy is that it can accomplish all the goals of open surgery with the benefit of decreased pain and a reduced recovery time in experienced hands. (virginiahernia.com)
  • laparoscopic adrenalectomy has a time that is less compared to that of the open approach and also has all the advantages of laparoscopic surgery (shorter hospital stay, shorter convalescence time, less postoperative pain, etc. (drmohitjain.com)
  • This type of surgery is an adrenalectomy and I was fortunate that it could be done laproscopically and also that my surgeon was one who uses robotics to perform it. (lizzyarmentrout.com)
  • However, a PSH duration of at least 12 months was significantly predicted before adrenalectomy (sensitivity 91.7%, specificity 41.2%, positive predictive value 52.4%, negative predictive value 87.5%, p = 0.05) by the presence of at least 2 out of low ACTH levels, increased UFC levels and cortisol levels after 1 mg-DST ≥ 3.0 µg/dL (83 nmol/L). Conclusion: The PSH occurrence and its duration are hardly predictable before surgery. (elsevier.com)
  • Innovation in endocrine surgery: robotic versus laparoscopic adrenalectomy. (medscape.com)
  • Outcomes of adrenal-sparing surgery or total adrenalectomy in phaeochromocytoma associated with multiple endocrine neoplasia type 2: an international retrospective population-based study. (medscape.com)
  • Dr. Michael Yeh, UCLA Endocrine Surgery, performing laparoscopic adrenalectomy. (uclahealth.org)
  • The Vattikuti Foundation is pleased is host a Masterclass on Robotic Adrenalectomy. (vattikutifoundation.com)
  • Dr Anup Kumar will show his technique of Robotic Adrenalectomy for Adenoma and challenging Adrenal Ganglioneuroma with RetroIVC extension, adhered to renal vessels. (vattikutifoundation.com)
  • Dr AK Hemal will show Technical advances in Robotic adrenalectomy including partial adrenalectomy. (vattikutifoundation.com)
  • This one-hour masterclass (plus discussion) aims to facilitate patient outcomes undergoing a robotic adrenalectomy. (vattikutifoundation.com)
  • Widespread adoption of robotic technology has positioned robotic adrenalectomy as an option in some medical centers. (univ-lorraine.fr)
  • Regarding the decrease in the number of oral antihypertensive agents, more agents were reduced in patients who underwent adrenalectomy. (nature.com)
  • Methods: We studied 80 patients (54 females, age 53.3 ± 11 years), who underwent adrenalectomy for CS (17 patients) or for AI (53 patients). (elsevier.com)
  • All listed patients underwent adrenalectomy. (acta-medica-eurasica.ru)
  • The aim of this study was to review the clinical outcomes after mineralocorticoid receptor (MR) antagonist treatment versus adrenalectomy treatment in patients with PA. (nature.com)
  • Available evidence indicated that the clinical outcomes were not different in PA patients treated with MR antagonist or adrenalectomy, except for a reduction in the number of antihypertensive agents. (nature.com)
  • For 2 decades we have performed too open and many minimally invasive adrenalectomies with all (Laparoscopic, Robotic or Single incision Laparoscopic) techniques with valuable outcomes. (wellht.com)
  • CONCLUSIONS: Outcomes of adrenalectomy based on clinically significant lateralization in 11 C-MTO-PET alone correspond to those based on 11 C-MTO-PET with concordant AVS lateralization. (tuni.fi)
  • To identify determinants of postsurgical biochemical outcomes, we compared the adrenal histopathology and the peripheral venous steroid profiles of patients with partial and absent or complete biochemical success after adrenalectomy for unilateral PA. (unibo.it)
  • Our study confirm that LESS adrenalectomy achieved similar clinical and functional outcomes as conventional multiport adrenalectomy for management of unilateral APA. (elsevier.com)
  • Future prospective studies are needed to further characterize frailty, examine its responsiveness to adrenalectomy, and assess its influence on health outcomes in patients with MACS. (elsevier.com)
  • Laparoscopic adrenalectomy is recommended for patients with mild autonomous cortisol secretion (MACS) secondary to a unilateral adenoma. (medscape.com)
  • Laparoscopic adrenalectomy in Delhi should be considered the procedure of choice for the surgical treatment of benign adrenal diseases. (drmohitjain.com)
  • We tested the hypothesis that adrenalectomy has become more common over time and that benign diseases have been increasingly represented among procedural indications. (qxmd.com)
  • The total number of adrenalectomies with a primary ICD-9-CM diagnostic code for benign adrenal neoplasm increased significantly, from 2.8 per 100,000 discharges in 1988 to 4.8 per 100,000 discharges in 2000 (p = 0.00002). (qxmd.com)
  • This is associated with an increase in the proportion of adrenalectomies performed for benign neoplasms. (qxmd.com)
  • The goal is to remove as much cancer as possible, which usually involves the surgical removal of the adrenal gland and some surrounding tissue through a procedure known as an adrenalectomy. (moffitt.org)
  • Adrenalectomy is the surgical removal of the adrenal gland or glands. (pacificneuroscienceinstitute.org)
  • A laparoscopic adrenalectomy is a surgical alternative to the procedure. (orangecountysurgeons.org)
  • Adrenalectomy is performed under general anesthesia, which means that the patient is asleep and completely unaware during the procedure. (orangecountysurgeons.org)
  • Adrenalectomy is a surgical procedure performed to remove adrenal glands (one or both). (medanta.org)
  • Procedure (How is a Adrenalectomy done? (medanta.org)
  • All discharged patients were identified whose primary ICD-9-CM procedure code was for adrenalectomy, regardless of the specific surgical approach (laparoscopic adrenalectomy was not reliably coded). (qxmd.com)
  • An adrenalectomy is a surgical procedure that removes the entire adrenal gland. (scripps.org)
  • Therefore, right partial adrenalectomy was preferred to left partial adrenalectomy during the planning of the surgical procedure. (spandidos-publications.com)
  • Roux-En-Y Gastric Bypass as a Primary Procedure for the Super-Obese Is laparoscopic adjustable gastric banded Roux-en-Y gastric bypass suitable as a primary operation in the super-super obese? (medscape.com)
  • Laparoscopic adrenalectomy is done under general anesthesia, and the patient's vitals are monitored throughout the procedure. (medicalonlinedirectory.com)
  • Laparoscopic adrenalectomy is done on carefully selected patients who are well-suited for the procedure. (medicalonlinedirectory.com)
  • Depending on the type of adrenalectomy procedure, you can expect to recover in two to six weeks. (medicalonlinedirectory.com)
  • Rarely (5-12%), the adrenal tumor may be cancerous (adrenocortical carcinoma), requiring adrenalectomy. (wikipedia.org)
  • The most common cause for adrenalectomy in Delhi is because a tumor is discovered in an adrenal gland that produces an excess of one of the hormones. (drmohitjain.com)
  • The effect of adrenalectomy on ghrelin secretion and orexigenic action. (neurotree.org)
  • For adrenocortical carcinoma (ACC), en-bloc radical resection with an intact capsule to R0 margins is recommended. (medscape.com)
  • Radical and partial nephrectomies, nephroureterectomies and adrenalectomies were done through 47, 20, 6 and 9 flank incisions in 80 patients, respectively. (canjurol.com)
  • Partial versus total adrenalectomy by the posterior retroperitoneoscopic approach: early and long-term results of 325 consecutive procedures in primary adrenal neoplasias. (medscape.com)
  • Although these adrenal masses do require evaluation, the majority of them (approximately 80%) do not require adrenalectomy. (wikipedia.org)
  • Patients suffering from tumours (of adrenal glands) require adrenalectomy. (medanta.org)
  • Many studies have compared laparoscopic versus robotic approaches to perform adrenalectomy and evaluated potential advantages to balance higher costs. (univ-lorraine.fr)
  • This review summarizes current available data regarding the use of the robotic system to perform adrenalectomy (RA) and its comparison with laparoscopic adrenalectomy (LA). (univ-lorraine.fr)
  • Laparoscopic transabdominal adrenalectomy is considered to be the standard of care for adrnalectomy. (univ-lorraine.fr)
  • Indications for adrenalectomy may seem straightforward at first. (medscape.com)
  • Trends in utilization of adrenalectomy in the United States: have indications changed? (qxmd.com)
  • There has been concern that an increased frequency of adrenal imaging along with the advantages of less morbidity could influence the indications for adrenalectomy. (qxmd.com)
  • The Nationwide Inpatient Sample (NIS) database was utilized to determine the incidence of adrenalectomy and the associated surgical indications in the United States between 1988 and 2000. (qxmd.com)
  • Assuming no significant change in disease prevalence during the study period, these data suggest that indications for adrenalectomy may have changed somewhat over that period. (qxmd.com)
  • Trends in adrenalectomy rates, indications, and physician volume: A statewide analysis of 1816 adrenalectomies. (qxmd.com)
  • Laparoscopic adrenalectomy: history, indications, and current techniques for a minimally invasive approach to adrenal pathology. (qxmd.com)
  • Robotic versus laparoscopic adrenalectomy: pluriannual experience in a high-volume center evaluating indications and Results. (medscape.com)
  • RESULTS: Adrenalectomy side was based on 11 C-MTO-PET alone in 14 cases and on AVS in 30 cases of whom 42 achieved complete and two partial biochemical cures. (tuni.fi)
  • We compared those operated based on 11 C-MTO-PET alone and those with concordant or discordant lateralization in 11 C-MTO-PET and AVS studies according to postoperative immunohistochemical findings and biochemical and clinical cure.RESULTS: Adrenalectomy side was based on 11 C-MTO-PET alone in 14 cases and on AVS in 30 cases of whom 42 achieved complete and two partial biochemical cures. (tuni.fi)
  • Adrenalectomy is utilized in order to treat an enlarged adrenal gland, high blood pressure caused by dysfunctional adrenal glands and Cushing's syndrome. (orangecountysurgeons.org)
  • Between January 2010 and August 2016, 123 patients underwent an LESS adrenalectomy by retroperitoneal approach in our hospital. (e-urol-sci.com)
  • The total number of adrenalectomies with a primary ICD-9-CM code for malignant adrenal neoplasm did not increase significantly: from 1.2 per 100,000 discharges in 1988 to 1.6 per 100,000 discharges in 2000 (p = 0.47). (qxmd.com)
  • In socially naive female prairie voles, cohabitation with an unfamiliar male resulted in a dramatic decline in serum corticosterone levels, When corticosterone levels were reduced via adrenalectomy, females developed partner preferences after 1 h of cohabitation, while sham-operated and untreated females required 3 h or more of nonsexual cohabitation to establish a partner preference. (rti.org)
  • Methods: Since October 2009, seven LESS retroperitoneal adrenalectomies have been completed successfully with a homemade single port created using an Alexis wound retractor as an access platform through a 3-cm incision beneath the tip of the 12th rib. (elsevier.com)
  • Laparoscopic adrenalectomy is a surgical technique used to remove the adrenal gland without making a big incision. (medicalonlinedirectory.com)
  • Techniques for adrenalectomy is largely divided into two types: open surgical laparotomy versus minimally invasive techniques. (wikipedia.org)
  • Polymorphic variation of CYP11B2 predicts postoperative resolution of hypertension in patients undergoing adrenalectomy for aldosterone-producing adenomas. (cdc.gov)