Excision of one or both adrenal glands. (From Dorland, 28th ed)
Tumors or cancer of the ADRENAL GLANDS.
A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
A benign neoplasm of the ADRENAL CORTEX. It is characterized by a well-defined nodular lesion, usually less than 2.5 cm. Most adrenocortical adenomas are nonfunctional. The functional ones are yellow and contain LIPIDS. Depending on the cell type or cortical zone involved, they may produce ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE.
An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Pathological processes of the ADRENAL GLANDS.
A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA.
A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Tumors or cancers of the ADRENAL CORTEX.
An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).
A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.
A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.
Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.
A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.
An anti-inflammatory 9-fluoro-glucocorticoid.
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Surgical removal or destruction of the hypophysis, or pituitary gland. (Dorland, 28th ed)
A benign epithelial tumor with a glandular organization.
An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
The outer layer of the adrenal gland. It is derived from MESODERM and comprised of three zones (outer ZONA GLOMERULOSA, middle ZONA FASCICULATA, and inner ZONA RETICULARIS) with each producing various steroids preferentially, such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and ANDROSTENEDIONE. Adrenal cortex function is regulated by pituitary ADRENOCORTICOTROPIN.
An area occupying the most posterior aspect of the ABDOMINAL CAVITY. It is bounded laterally by the borders of the quadratus lumborum muscles and extends from the DIAPHRAGM to the brim of the true PELVIS, where it continues as the pelvic extraperitoneal space.
Radiation therapy used to treat the PITUITARY GLAND.
A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
A rare benign tumor of the adrenal gland, several centimeters in diameter, composed in varying proportions of adipose tissue, lymphocytes, and primitive myeloid cells, probably a developmental abnormality. (Dorland, 27th ed)
Symptom complex due to ACTH production by non-pituitary neoplasms.
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.
An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
Product of epinephrine O-methylation. It is a commonly occurring, pharmacologically and physiologically inactive metabolite of epinephrine.
Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.
A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.
Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
Examinations that evaluate and monitor hormone production in the adrenal cortex.
A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE.
Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
A general class of ortho-dihydroxyphenylalkylamines derived from tyrosine.
A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.
Nucleus in the anterior part of the HYPOTHALAMUS.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
Pathological processes of the ADRENAL CORTEX.
Services offered to the library user. They include reference and circulation.
Private, not-for-profit hospitals that are autonomous, self-established, and self-supported.
Care of patients by a multidisciplinary team usually organized under the leadership of a physician; each member of the team has specific responsibilities and the whole team contributes to the care of the patient.
Hospitals owned and operated by a corporation or an individual that operate on a for-profit basis, also referred to as investor-owned hospitals.
Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.
Compliance with a set of standards defined by non-governmental organizations. Certification is applied for by individuals on a voluntary basis and represents a professional status when achieved, e.g., certification for a medical specialty.

Maternal adrenocortical hormones maintain the early development of pancreatic B cells in the fetal rat. (1/1561)

To investigate the effect of maternal adrenocortical hormones on the development of fetal pancreatic islet cells, pregnant rats were adrenalectomised on d 6 of gestation. On d 12-16 the growth patterns of fetal insulin-producing B cells, glucagon-producing A cells, and somatostatin-producing D cells were observed histometrically. Maternal adrenalectomy resulted in growth retardation of fetal B cells on d 12-15. Maternal corticosterone therapy prevented this retardation. Maternal adrenalectomy, however, did not affect the developmental patterns of A and D cells. By Western blotting and immunohistochemistry, glucocorticoid receptors were demonstrated to be present in the islet cells from d 12 to d 15. These results suggest that maternal adrenocortical hormones, glucocorticoids in particular, maintain the early development of fetal pancreatic B cells through their specific intracellular glucocorticoid receptor.  (+info)

Pharmacodynamic actions of (S)-2-[4,5-dihydro-5-propyl-2-(3H)-furylidene]-1,3-cyclopentanedione (oudenone). (2/1561)

The pharmacodynamic actions of (S)-2-[4,5-dihydro-5-propyl-2(3H)-furylidene]-1,3-cyclopentanedione (oudenone) were studied in both anesthetized animals and isolated organs. Oudenone (10--40 mg/kg i.v.) induced an initial rise in blood pressure followed by a prolonged hypotension in the anesthetized rats. In unanesthetized spontaneously hypertensive rats (SHR), oudenone (5--200 mg/kg p.o.) caused a dose-related decrease in the systolic blood pressure. The initial pressor effect was diminished by pretreatments with phentolamine, guanethidine, hexamethonium and was abolished in the pithed rats. In addition, intracisternal administrations of oudenone (100--600 mug/kg) showed a marked increase in blood pressure in the anesthetized rats, suggesting that the pressor effect may be due to centrally mediated actions. Oudenone, given intra-arterially into the femoral artery (400--800 mug/kg), caused a long-lasting vasodilation in anesthetized dogs. At a relatively high dose (40 mg/kg i.v.), oudenone antagonized all pressor responses to autonomic agents and central vagus nerve stimulation in anesthetized rats and dogs, however, oudenone showed no anti-cholinergic,-histaminergic, beta-adrenergic and adrenergic neuron blocking properties.  (+info)

Primary aldosteronism with aldosterone-producing adrenal adenoma in a pregnant woman. (3/1561)

A 30-year-old pregnant woman complained of muscle weakness at 29 weeks' gestation. She was hypertensive with severe hypokalemia. Lower plasma renin activity and higher aldosterone level than the normal values in pregnancy suggested primary aldosteronism. A cesarean delivery was performed at 31 weeks' gestation because of pulmonary congestion. The neonatal course was uncomplicated. The laparoscopic adrenalectomy for a 2.0-cm right adrenal adenoma resulted in normalizing of her blood pressure and serum potassium level. Although primary aldosteronism is rare, especially during pregnancy, it should be always considered as one of etiologies of hypertension in pregnancy.  (+info)

Activation of the adult mode of ovine growth hormone receptor gene expression by cortisol during late fetal development. (4/1561)

The developmental and tissue-specific regulation of growth hormone receptor (GHR) mRNA expression is complex and involves alternate leader exon usage. The transcript composition of hepatic GHR mRNA has therefore been determined in fetal sheep during late gestation and after experimental manipulation of fetal plasma cortisol levels by fetal adrenalectomy and exogenous cortisol infusion, using RNase protection assays and a riboprobe containing exons 1A, 2, and 3 of the ovine GHR gene. Expression of the adult liver-specific GHR mRNA transcript containing exon 1A was not detected earlier than 138 days of gestation (term 145 +/-2 days). Thereafter, expression of this leader exon increased and accounted for 25-30% of the total GHR mRNA in the fetal liver at term. Hepatic GHR mRNA derived from leader exons other than 1A was detectable at 97 days and increased in abundance toward term in parallel with the normal prepartum rise in fetal plasma cortisol. Abolition of this cortisol surge by fetal adrenalectomy prevented both the activation of exon 1A expression and the prepartum rise in GHR mRNA derived from the other leader exons in fetal ovine liver. Conversely, raising cortisol levels by exogenous infusion earlier in gestation prematurely activated exon 1A expression and enhanced the abundance of GHR mRNA transcripts derived from the other leader exons. Cortisol therefore appears to activate the adult mode of GHR gene expression in fetal ovine liver during late gestation. These observations have important implications for the maturation of the somatotrophic axis and for the onset of GH-dependent growth after birth.  (+info)

Glucocorticoid enhances interleukin-1-induced pressor response in freely moving rats through its effect on nitric oxide release. (5/1561)

We investigated whether changes in nitric oxide (NO) release might be responsible for the modulation by glucocorticoids of the pressor response to i.p. injection of interleukin-1beta (IL-1beta) in freely moving rats. In such rats, IL-1beta (10 microgram/kg) induced a biphasic pressor response, with a rise in the plasma concentration of NOx (NO2(-) and NO3(-): metabolites of NO) during the second phase. Systemic pretreatment with an exogenous glucocorticoid, dexamethasone (0.5 mg/kg), enhanced the second phase of the pressor response and completely suppressed the increase in plasma NOx. Treatment with Nomega-nitro-L-arginine methyl ester (L-NAME, a nonspecific NO synthase inhibitor), enhanced the pressor response while attenuating the increase in plasma NOx. After bilateral adrenalectomy, IL-1beta induced a smaller pressor response, but a larger increase in plasma NOx; dexamethasone reversed these changes. Our results suggest that endogenous NO moderates the pressor response to IL-1beta in freely moving rats, and that glucocorticoids enhance the IL-1beta-induced pressor response at least in part by reducing endogenous NO release.  (+info)

Endogenous glucocorticoids protect against cytokine-mediated lethality during viral infection. (6/1561)

Certain cytokines activate the hypothalamic-pituitary-adrenal axis for glucocorticoid release, and these hormones can protect against cytokine-mediated pathologies. However, endogenous activation of such a pathway has not been established during infections. A prominent glucocorticoid response peaks 36 h following murine CMV (MCMV) infection, coincident with circulating levels of the cytokines IL-12, IFN-gamma, TNF, and IL-6, and dependent on IL-6 for maximal release. These studies examined functions of the hormone induction. Mice rendered glucocorticoid deficient by adrenalectomy were more susceptible than intact mice to MCMV-induced lethality, and the increased sensitivity was reversed by hormone replacement. Lack of endogenous glucocorticoids resulted in increases in IL-12, IFN-gamma, TNF, and IL-6 production, as well as in mRNA expression for a wider range of cytokines, also including IL-1 alpha and IL-1 beta. Viral burdens did not increase, and actually decreased, in the livers of glucocorticoid-deficient mice. TNF, but not IFN-gamma, was required for increased lethality in the absence of endogenous hormone. These results conclusively demonstrate the importance of induced endogenous glucocorticoids in protection against life-threatening effects resulting from infection-elicited cytokine responses. Taken together with the dependence on induced IL-6, they document existence of an immune system-hypothalamic-pituitary-adrenal axis pathway for regulating endogenous responses to viral infections.  (+info)

Mechanisms underlying the anti-inflammatory actions of central corticotropin-releasing factor. (7/1561)

Immune activation of hypothalamic corticotropin-releasing factor (CRF) provides a negative feedback mechanism to modulate peripheral inflammatory responses. We investigated whether central CRF attenuates endothelial expression of intercellular adhesion molecule 1 (ICAM-1) and leukocyte recruitment during endotoxemia in rats and determined its mechanisms of action. As measured by intravital microscopy, lipopolysaccharide (LPS) induced a dose-dependent increase in leukocyte rolling, adhesion, and emigration in mesenteric venules, which was associated with upregulation of endothelial ICAM-1 expression. Intracisternal injection of CRF abrogated both the increased expression of ICAM-1 and leukocyte recruitment. Intravenous injection of the specific CRF receptor antagonist astressin did not modify leukocyte-endothelial cell interactions induced by a high dose of LPS but enhanced leukocyte adhesion induced by a low dose. Blockade of endogenous glucocorticoids but not alpha-melanocyte-stimulating hormone (alpha-MSH) receptors reversed the inhibitory action of CRF on leukocyte-endothelial cell interactions during endotoxemia. In conclusion, cerebral CRF blunts endothelial upregulation of ICAM-1 and attenuates the recruitment of leukocytes during endotoxemia. The anti-inflammatory effects of CRF are mediated by adrenocortical activation and additional mechanisms independent of alpha-MSH.  (+info)

Fetal rat adrenal steroidogenesis and steroid transfer to adrenalectomized mother. (8/1561)

On the 22nd day of gestation in rats, fetuses of acutely adrenalectomized mothers were injected subcutaneously with 0.43 muCi 4-14C-progesterone in 0.05 ml saline. Ten and 20 min after injection to fetuses, samples were taken to determine the 14C-progesterone metabolites in the plasma and adrenal glands. After extraction of the samples taken, the metabolites were separated by two-dimensional thin-layer chromatography and identified by autoradiography. 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone, corticosterone and 11beta-hydroxyprogesterone were identified in the plasma of injected fetuses, and, in far smaller amounts, in the plasma of their mothers. The plasma of noninjected fetuses also contained very small amounts of these corticoids. The fetal adrenal glands contained far smaller amounts of radioactive steroids than the fetal plasma did. The results obtained show that steroids of fetal origin can cross the placenta in and out, constituting evidence that the fetal adrenal glands are the only source of the plasma corticoids of their adrenalectomized mothers.  (+info)

AIM To analyze patient demographics, pathology, surgical procedure and outcome in initial 24 consecutive patients who underwent laparoscopic adrenalectomy in our department. METHODS Twenty four patients underwent laparoscopic adrenalectomy between September 2000 and August 2005. There were 12 males and 12 females with a mean age of 44.6 years (range 25-68 years). The indications for adrenalectomy were pheochromocytoma (13 patients), Cushings syndrome (5 patients), myelolipoma (2 patients), adrenal cyst (2 patients), aldosteronoma (1 patient) and adrenal incidentaloma (1 patient). Nineteen of our patients with functioning adrenal tumours were prepared preoperatively for periods ranging up to 2 weeks by the endocrinologist. All laparoscopic adrenalectomies were performed via lateral transperitoneal approach using standard four-port technique. Patients with pheochromocytoma and Cushings syndrome were monitored in the surgical intensive care unit during immediate postoperative period. The clinical and
Since 1992, transabdominal LA(laparoscopic adrenalectomy) has been a standard method of adrenalectomy. This traditional method has been used widely because this procedure provides wide view of the whole abdomen which is familiar to surgeons. But due to its unique location at retroperitoneum, adrenal is still not easy to approach. So various retroperitoneal approaches were designed and adjusted. Among those, PRA(posterior retroperitoneal adrenalectomy) has showed good outcomes in many institutes. PRA facilitates direct approach to kidney and adrenal gland, and so operative time can be shortened. But there has been no randomized controlled trial between these two methods.. Therefore, as experienced surgeons in both methods, we want to practice this study. ...
Introduction: Patients with subclinical Cushing s syndrome (SCS) present with increased cardiovascular morbidity and mortality, however, the beneficial effect of adrenalectomy on cardiovascular risk factors is uncertain.. Objective: Systematic meta-analysis to determine the effect of adrenalectomy vs conservative follow-up on cardiovascular risk factors in patients with adrenal tumors and SCS.. Methods: We searched 6 databases through July 2014. Pairs of independent reviewers selected studies and appraised the risk of bias. We included and extracted studies with at least five SCS patients with adrenal tumors undergoing adrenalectomy where outcomes of interest were measured before and after surgery. Outcomes of interest included hypertension, diabetes, dyslipidemia, and obesity. In majority of studies, improvement of an outcome was defined as postsurgical decrease in dose, number or discontinuation of medications used to treat the comorbidity.. Results: Definition of SCS was heterogeneous among ...
Laparoscopic Adrenalectomy Adrenalectomy is the surgical removal of all or part of an adrenal gland. The most common indicator for adrenalectomy is the presence of hormone-producing adrenal tumors. Prognosis is dependent upon individual medical history.
TY - JOUR. T1 - Corticosteroids and ACTH are not required for compensatory adrenal growth. AU - Engeland, W. C.. AU - Shinsako, J.. AU - Dallman, M. F.. PY - 1975. Y1 - 1975. N2 - The authors tested the hypothesis that unilateral adrenalectomy results in decreased glucocorticoid secretion, reflexly elevated ACTH secretion, and, consequently, compensatory adrenal growth. Plasma ACTH and corticosterone and right adrenal weight were measured during the first 10 days after left adrenalectomy or sham adrenalectomy in young male rats. There is a decrease in plasma corticosterone after unilateral adrenalectomy compared to sham adrenalectomy that persists for 1 h. ACTH is elevated only at 2 h after unilateral adrenalectomy compared to sham operated rats. Treatment with dexamethasone, shown to abolish the ACTH and corticosterone responses to laparotomy with intestinal traction, resulted in significantly increased adrenal weight after unilateral adrenalectomy by 6 h (wet or dry weight), and at 24 h. ...
TY - JOUR. T1 - Effects of adrenalectomy on CCD. T2 - Evidence for diferential response of two cell types. AU - Muto, S.. AU - Giebisch, G.. AU - Sansom, S.. PY - 1987/12/1. Y1 - 1987/12/1. N2 - Electrophysiological and chemical methods were used to determine the Na and K transport properties of the isolated cortical collecting duct (CCD) of control and adrenalectomized (ADX) rabbits. Net fluxes of Na (J(Na)) and K (-J(K)) in controls were 5.7 and 3.2 pmol·mm-1·min-1 and in ADX were 1.0 and 0.7 pmol·mm-1·min-1, respectively, similar to electrically determined rates. In separate experiments, blind impalement of cells from adrenal intact (group 1), ADX (group 2), and ADX rabbits treated with deoxycorticosterone (group 3) allowed identification of two distinct cell types, majority cells (MA) and minority cells (MI). In all groups, MA were distinguished from MI by a relatively high basolateral membrane potential (-V(b)), low apical membrane fractional resistance (FR(a)), and presence of apical ...
en] We investigated hemodynamics and plasma catecholamine concentrations in eight consecutive patients undergoing laparoscopic adrenalectomy for suspected pheochromocytoma. The same anesthesia protocol was used in all patients: a continuous infusion of sufentanil 0.5 microg x kg(-1) x h(-1) and isoflurane 0.4% (end-tidal) in 50% N2O/O2. Systolic arterial pressure was maintained between 120 and 160 mm Hg by adjusting an infusion of nicardipine, a calcium-channel blocker, while tachycardia (,100 bpm) was treated by 1-mg boluses of atenolol. Hemodynamics (thermodilution technique) and plasma catecholamine concentrations were measured before surgery, after the induction of anesthesia, after turning the patient to the lateral position, during pneumoperitoneum, during tumor manipulation, after adrenalectomy, and at the end of surgery. Two events resulted in significant catecholamine release: creation of the pneumoperitoneum and adrenal gland manipulation. As a consequence, a twofold increase in ...
Scherzer, A L.; Azar, H A.; Naujoks, G; and Williams, J, Effect of castration and adrenalectomy on the thymus and other lymphoid organs of mice. Abstr. (1963). Subject Strain Bibliography 1963. 923 ...
Semantic Scholar extracted view of [Endocrine factors and metabolism of thiamine. I. Effect of adrenalectomy on the uptake and phosphorylation of thiamine in the liver of (alloxan) diabetic and nondiabetic rats]]. by V. Cappelli et al.
Wilson, Ollie Bernice, The effect of adrenalectomy on the percent of hemolysis of erythrocytes in rats (1955). ETD Collection for AUC Robert W. Woodruff Library. 941 ...
View Poster. INTRODUCTION. Adrenalectomy is an operation performed by both urologists and general surgeons, however the majority are performed by general surgeons. We wanted to investigate whether there was a difference in outcomes based on surgical specialty performing the procedure. If no differences exist, an argument can be made that urologists should be doing more adrenalectomies. METHODS. The National Surgical Quality Improvement Project (NSQIP) Participant Use File (PUF) was queried to extract all cases of adrenalectomies performed during the years 2011-2015. The following two CPT codes were used: 60540 (open) and 60650 (laparoscopic). The data were stratified by surgical specialty who performed the adrenalectomy (urology or general surgery). Our outcomes of interest included post-surgical complications, reoperations, 30-day readmission, mortality, and hospital length of stay. RESULTS. A total of 3358 patients who underwent adrenalectomy were included, 3012 (90%) by a general surgeon and ...
Wiernik, P H., Effect of starvation of intact and adrenalectomized mice bearing lymphosarcoma p1798 on tumor regression and ribonuclease activity. (1970). Subject Strain Bibliography 1970. 1576 ...
Author(s): Seib, CD; Greenblatt, DY; Campbell, MJ; Shen, WT; Gosnell, JE; Clark, OH; Duh, QY | Abstract: Background Adrenalectomy is a complex procedure performed in many settings, with and without residents and fellows. Patients often ask, Will trainees be participating in my operation? and seek reassurance that their care will not be adversely affected. The purpose of this study was to determine the association between trainee participation and adrenalectomy perioperative outcomes. Study Design We performed a cohort study of patients who underwent adrenalectomy from the 2005 to 2011 American College of Surgeons NSQIP database. Trainee participation was classified as none, resident, or fellow, based on postgraduate year of the assisting surgeon. Associations between trainee participation and outcomes were determined via multivariate linear and logistic regression. Results Of 3,694 adrenalectomies, 732 (19.8%) were performed by an attending surgeon with no trainee, 2,315 (62.7%) involved a resident,
Hector R Romero, MD, Victoria Cerecedo, MD, Mauricio Sierra, MD, David Velazquez, MD PhD, Nicholas Williams, FRACS, Alexander P Heinze. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran. Background. Laparoscopic adrenalectomy (LA) is associated with several advantages over the open equivalent such as less postoperative pain, use of lesser dose of analgesics, decreased morbity, better cosmesis, an earlier return to work and regular activities, shorter hospital stay, reduced costs and greater patient satisfaction. However, the procedure has also been associated with limitations such as tumors larger than 6 cm, the diagnosis of pheochromocytoma or malignant lesions. There´s still ongoing debate on which is the appropriate limit for laparoscopic resection regarding tumor size. It is traditionally said that LA should be avoided if evidence of periadrenal infiltration is recognized preoperatively because invasion may compromise peripheral structures and because the capsule should ...
During the study period 79 patients met inclusion criteria with an average age of 54 years (range 21-83). Average ASA score was 3 and 66% of patients were female. A laparoscopic approach was employed in 95% with a conversion rate of 3.8%. Average operating room time was 127 minutes (range 50-307) and blood loss of 114ml (range 10-1600). Unilateral adrenalectomy was performed in all but 1 patient who underwent bilateral adrenalectomy for pheochromocytoma. The most common indication for surgery was primary hyperaldosteronism caused by an aldosterone producing adenoma (63%). Average postoperative length of stay was 2.4 days (range 1-15). Morbidity and mortality were 13% and 0 respectively. Tumor size was significantly higher in patients with nonfunctional tumors (4.4cm vs. 2.9cm, p,0.003 ...
This Laparoscopic Adrenalectomy consultation is part of a series of consultations with surgical specialists at the University of California, San Diego.
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1. The effects of replacing a 1% NaCl drinking solution with Na+-free water for 2 days on body weight and fluid and electrolyte balances were studied in adrenalectomized and sham-operated rats.. 2. Eight weeks after operation, after the animals had been drinking Na+-free water for 2 days, some adrenalectomized animals (about 75%; designated group 1) experienced body weight losses which were outside the 99% confidence limits for the sham-operated rats (- 9.2 to + 5.3 g) whereas the remainder (designated group 2) were indistinguishable from the controls.. 3. The body weight loss in group 1 was associated with negative fluid, Na+ and K+ balances. In group 2 rats, fluid balance was maintained as well as in the sham-operated rats, but their handling of Na+ and K+ was different.. 4. In a separate experiment, plasma aldosterone, corticosterone, catecholamine and solute concentrations were measured in adrenalectomized rats from groups 1 and 2 (selected on the basis of body weight loss whilst drinking ...
Patients with a mild form of Cushing syndrome, a metabolic disorder caused by adrenal tumors, demonstrate substantial clinical improvement after adrenalectomy.
The brain 5-HT (serotonin) system and circulating corticosteroids are in close interaction and both are implicated in the pathogenesis of affective disorders. The 5-HT1A receptor is thought to play a major role in this relationship. However, the recently cloned 5-HT7 receptor may also be involved, given its pharmacological similarities to the 5-HT1A receptor and its high expression in corticolimbic structures. Using in situ hybridization histochemistry, we have investigated 5-HT7 and 5-HT1A receptor mRNA expression in selected areas of the rat brain 7 days post-adrenalectomy. 5-HT7 receptor mRNA was increased in CA1 and CA3b after adrenalectomy, with no alterations in other hippocampal subfields or in retrosplenial cortex. Adrenalectomy was associated with a marked increase of 5-HT1A receptor mRNA in dentate gyrus, CA3 and CA2, but not in CA1, nor in the raphe. These data indicate that circulating adrenal steroids have a inhibitory role on the expression of hippocampal 5-HT7 receptors as well as 5-HT1A
N Engl J Med. 1981 Sep 3;305(10):545-51. Clinical Trial; Comparative Study; Randomized Controlled Trial; Research Support, U.S. Govt, P.H.S.
PM Stewart, J Corrie, JR Seckl, CRW Edwards, PL Padfield; A Rational Approach in Assessing the Need for Corticosteroid Replacement Therapy. Clin Sci (Lond) 1 January 1988; 74 (s18): 67P-68P. doi: https://doi.org/10.1042/cs074067Pc. Download citation file:. ...
Sixteen patients (eight males and eight females) underwent an adrenalectomy. The demographic composition of patients is summarized in Table 1. The patients mean age was 58.00± 11.34 years (range, 33-76 years). Three patients had undergone previous abdominal surgery; a 54-year-old female who underwent surgery due to an ectopic pregnancy 25 years ago, a 68-year-old female who underwent an appendectomy 50 years ago, and a 69-year-old female who underwent a hysterectomy with uterine leiomyoma 25 years ago. Regarding other comorbidities, 11 patients had hypertension, two of which had diabetes mellitus. Among patients with both hypertension and diabetes mellitus, one patient had a history of microvascular angina. Among the other patients with hypertension, one patient had angina pectoris, one had unstable angina, one had hypertrophic cardiomyopathy, and one had both chronic renal failure and cerebral infarction. Regarding the location of the tumors, the tumor was positioned on the right adrenal ...
One adrenal gland sits above each of your kidneys. Your two adrenal glands produce various hormones that help regulate your metabolism, immune system, blood pressure, blood sugar and other essential functions. If a noncancerous (benign) adrenal tumor or adrenal cancer is discovered, you may require an adrenalectomy (uh-dree-nul-EK-tuh-me) to remove the adrenal gland that has the tumor. If one adrenal gland is removed, the other takes over full function without the need for supplemental medications.
Adrenalectomy is surgery to remove all or part of one or both adrenal glands. The glands are above the kidneys. They make hormones that affect nearly every organ in the body. These hormones include adrenaline and cortisol. They do many things in the body. For example, they help control blood pressure. They help the body deal with stress. And they control the breakdown of fats and proteins in the liver. This surgery may be done to remove a tumour that is or isnt cancer. It also may be done for people with Cushings syndrome, a problem that causes too much cortisol in the body. It may be done to remove a tumour that makes too much adrenaline.. The surgery may be done through a single cut (incision). This is called open surgery. Or your child may have laparoscopic surgery. To do this, the doctor puts a lighted tube, or scope, and other tools through several small cuts.. If your child has laparoscopic surgery, he or she may be able to leave the hospital the next day. With open surgery, your child ...
Kirman I, Cekic V, Poltaratskaia N, et al. Plasma from patients undergoing major open surgery stimulates in vitro tumor growth: lower insulin-like growth factor binding protein 3 levels may, in part, account for this change. Surgery 2002;132:186-92.PubMedCrossRefGoogle Scholar ...
Learn more about Adrenalectomy -- Open Surgery at Grand Strand Medical Center DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
RIOS GONZALEZ, Emilio y MARTINEZ-PINEIRO LORENZO, Luís. Current role of lymphadenectomy and adrenalectomy in radical surgery for renal cancer. Actas Urol Esp [online]. 2009, vol.33, n.5, pp.562-568. ISSN 0210-4806.. Radical nephrectomy is the only curative treatment for renal cell cancer. Standard treatment includes ipsilateral adrenalectomy and lymph node dissection. In recent years, development of nephron-sparing surgery and early detection of small renal tumors has led to question this approach. The role of lymphadenectomy and adrenalectomy in surgical treatment of renal cancer is reviewed.. Palabras clave : Renal cell cancer; Lymphadenectomy; Adrenalectomy. ...
Os objetivos deste estudo foram avaliar os efeitos da pinealectomia, da adrenalectomia e da adrenalectomia mais pinealectomia na quantificação das células espermatogênicas de ratos. Assim, 32 ratos adultos Wistar com peso corporal médio de 331,7± 15,5g foram alocados em um dos seguintes tratamentos: (a) um grupo controle simulado, composto de nove animais; (b) dez animais pinealectomizados; (c) sete animais adrenalectomizados e (d) seis animais pinealectomizados+adrenalectomizados. Não foram encontradas diferenças significativas entre grupos para os seguintes parâmetros: pesos corporal, dos testículos, da próstata e das vesículas seminais, diâmetro dos túbulos seminíferos, número de células por corte transversal de túbulo seminífero (espermatócitos primários em paquíteno, espermátides arredondadas, células de Sertoli) e números de células espermáticas por célula de Sertoli (espermatócitos primários em paquíteno e espermátides arredondadas). Apesar do peso ...
Responses to angiotensin II were also depressed in adrenalectomized rats (Figure 2). Bolus angiotensin injections in isolated lungs produced typical transient
The administration of 3-methylcholanthrene to rats is accompanied by an increase in the incorporation of orotic acid-14C into the 45 S cytoplasmic particle in the liver. The elevation reaches a maximum at 15 hr after the injection of the polycyclic hydrocarbon and diminishes to control values by 36 hr. This effect was also observed in adrenalectomized animals, eliminating any role of the adrenal corticosteroids in the phenomenon. In addition, the turnover of 18 and 28 S ribosomal RNA in liver cytoplasm was elevated after administration of the polycyclic hydrocarbon. These results suggest that the synthesis of ribosomal constituents, in particular, ribosomal RNA, may play an important role in the induction phenomenon observed in liver after administration of 3-methylcholanthrene.. ...
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1. A human urinary thermostable glycoprotein (ABG-TsU) believed to be a homologue of the plasma aldosterone-binding globulin (ABG) was isolated and purified by differential ultra-filtration, ion-exchange chromatography and gel filtration to electrophoretic homogeneity; it showed a charge heterogeneity in electrofocussing.. 2. ABG-TsU was administered intraperitoneally to male rats in small daily doses (7 μg/day per rat). Sustained hypertension developed in 5-8 days.. 3. The treated rats showed no changes in plasma electrolytes, aldosterone or plasma renin activity; however, a significant increase in heart weight was observed.. 4. This hypertension appears to be adrenal dependent since it is prevented by bilateral adrenalectomy or administration of an aldosterone antagonist, but not by adrenalectomy when aldosterone is given concomitantly with ABG-TsU.. ...
Hydrocortisone (cortisol) is secreted by the adrenal cortex and has both glucocorticoid and mineralocorticoid effects. The term glucocorticoid derives...
Incidental findings of adrenal tumours,incidentalomas, occur in 1-5 % in the general population and 10-25 % of these patients will exhibit biochemical mild hypercortisolism. Although the patients do not have clinical signs of classical Cushings syndrome, they have an increased risk for hypertension, dyslipidemia, diabetes mellitus, osteoporosis and obesity.. The hypothesis of the study is, that surgery of the adrenal adenoma responsible for the increased secretion of cortisol, will in part cure or ameliorate the metabolic syndrome. ...
A 27 year old female G2 p1001 @ 7 week gestation was referred to our institution without obstetric services for persistent hypertension, palpitations, headache, lightheadedness, and fatigue and a family history of pheochromocytoma. Initial 24 hour urine revealed elevated dopamine, epinephrine and plasma norepinephrine levels. An abdominal MRI showed a 1.9 x 2.2 cm mass in the right adrenal gland along with several enlarged epigastric lymph nodes. The patient was started on phenoxybenzamine and labetalol. A laparoscopic adrenalectomy was planned at 15 week gestation pending stable hemodynamics. Surgery planned to have gastroenterology do an upper endoscopy with biopsy of the epigastric lymph nodes a week prior to her surgery, however, at the insistence of the obstetric anesthesiologist, the endoscopic procedure was scheduled at the time of the laparoscopy. Endocrinology was followed her vital signs on an outpatient basis prior to surgery, which required an increase in alpha and beta blockade due ...
possible extrathymic T cells (i.e. CD56þ T cells and CD57þ T Therefore, we used adrenalectomized mice in an attempt to cells) [9,10]. It was found that cell populations could be classified identify possible influences on the circadian rhythm [17]. These into two groups: one group with daytime rhythm includes granu- mice lost such circadian rhythms, implying some hormonal reg- locytes, monocytes, NK cells, extrathymic T cells, gd T cells, and ulation. However, because of impaired mobility, they also lost the CD8þ cells. The other, with night rhythm, includes conventional T variation of their physical activity round the clock. Changes in the and B cells, ab T cells, and CD4þ cells. It is well known that NK activity of the autonomic nervous system might affect leucocyte cells, extrathymic T cells and gd T cells are involved in natural subsets, some of them carrying adrenergic or cholinergic receptors immunity and are more primitive than conventional T (and ab T) [11,12]. There are many reports ...
History In my most recent post, which was a 2-year check-in since my MS diagnosis, I discussed a new health concern. In June of 2020, I had an ultrasound on my liver after some of my labs came back bad. The liver issue resolved on its own, but the ultrasound found a tumor on my…
History In my most recent post, which was a 2-year check-in since my MS diagnosis, I discussed a new health concern. In June of 2020, I had an ultrasound on my liver after some of my labs came back bad. The liver issue resolved on its own, but the ultrasound found a tumor on my…
It has repeatedly been shown that angiotensin II pretreatment enhances the subsequent hypoxic pressor responses in preparations perfused with artificial
1. When the suprarenal glands are removed from drakes they die after a mean interval of about 8 hours. They can be kept alive by the hourly injection of cortical extract. The amount of extract which must be injected varies at different times in the year, becoming much larger during the breeding season.. 2. The testes of the drake out of the breeding season weigh 1 to 4 grams. From January to May they increase in size to about 80 grams. During June they rapidly decline to the former small size. The curve of change in weight is closely parallel to the curve for the amount of cortical extract required after adrenalectomy, but the changes in the latter curve precede those in the former.. 3. After adrenalectomy castrated drakes require one third to one half of the amount of cortical extract necessary to keep normal birds alive during the breeding season. The increase in requirement of cortical extract during the breeding season is not due to the large amount of male hormone in the circulation, since ...
Nuchtern JG, London WB, Barnewolt CE, Naranjo A, McGrady PW, Geiger JD, Diller L, Schmidt ML, Maris JM, Cohn SL, Shamberger RC. A prospective study of expectant observation as primary therapy for neuroblastoma in young infants: a Childrens Oncology Group study. Ann Surg. 2012 Oct; 256(4):573-80 ...
We found no significant adaptation of the HPA axis to chronic FS, but did of glucose and other variables. A single exposure to FS did not cause long-term effects on the responsiveness of the HPA axis to the same stressor in contrast to that observed after IMO. We then studied the effects of single versus repeated exposure to IMO on the HPA response to the same stressor in both sham-operated and adrenalectomized rats maintained with corticosterone in their drinking saline (ADX+B). In sham rats, daily exposure to IMO had similar effects on the HPA axis that a previous single session. In contrast, in ADX+B rats, a reduction of the ACTH response to the stressor was observed in repeated but not single IMO rats. The present result suggest that the glucocorticoids are not mandatory for the development or adaptation of the HPA axis to chronic IMO, but they may be involved in the induction or expression of long-term effects of IMO on the HPA responsiveness to the same stressor. In order to better study ...
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Exacerbation of autoimmune thyroid dysfunction after unilateral adrenalectomy in patients with Cushings syndrome due to an adrenocortical adenoma
1. Marked hypertension was induced in adrenalectomized rats on a sodium-restricted intake by the administration of cortisone acetate; on a similar regimen, adrenalectomized rats receiving DCA failed to become hypertensive. 2. The incorporation of a liberal amount of sodium in the diet of adrenalectomized rats receiving cortisone acetate resulted in a lesser degree of hypertension; whereas on a similar regimen, DCA-injected animals became strikingly hypertensive, as has been previously reported. 3. The presence of hypertension in the cortisone acetate-treated rats was not associated with histological evidence of renal damage or serum electrolyte disturbance, such as was observed in hypertensive animals receiving DCA. 4. The hypertension in sodium-restricted normal rats receiving cortisone acetate was less striking than in similarly treated adrenalectomized animals. On a liberal sodium intake similar degrees of hypertension were noted in both intact and adrenalectomized groups. 5. To approximate ...
TY - JOUR. T1 - Laparoscopic Versus Open Adrenalectomy for Adrenocortical Carcinoma. T2 - Surgical and Oncologic Outcome in 152 Patients: Editorial Comment. AU - Cadeddu, Jeffrey A. PY - 2011. Y1 - 2011. UR - http://www.scopus.com/inward/record.url?scp=84937218160&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84937218160&partnerID=8YFLogxK. U2 - 10.1016/j.juro.2010.12.025. DO - 10.1016/j.juro.2010.12.025. M3 - Article. AN - SCOPUS:84937218160. VL - 185. SP - 1222. JO - Journal of Urology. JF - Journal of Urology. SN - 0022-5347. IS - 4. ER - ...
TY - JOUR. T1 - Hormonal mediation of the analgesia produced by food deprivation. AU - Hamm, Robert J.. AU - Knisely, Janet S.. AU - Watson, Ann. AU - Lyeth, Bruce G. AU - Bossut, D. F B. PY - 1985. Y1 - 1985. N2 - Research has demonstrated that a wide variety of environmental conditions are capable of producing analgesia. In the present experiment, the analgesia produced by 24 hr of food deprivation was examined following adrenalectomy, hypophysectomy, naltrexone (7 mg/kg), dexamethasone (0.4 mg/kg), or saline treatment. Results revealed that 24 hr of starvation elicited an analgesic response in the saline-treated and sham-operated groups. Naltrexone, dexamethasone, adrenalectomy, and hypophysectomy blocked the analgesia produced by food deprivation. The results demonstrate that 24 hr of food deprivation induced an opiate-mediated analgesic system that involves hormonal factors.. AB - Research has demonstrated that a wide variety of environmental conditions are capable of producing analgesia. ...
Fingerprint Dive into the research topics of Adrenal metastases from adenocarcinoma of the esophagogastric junction: Adrenalectomy and long-term survival. Together they form a unique fingerprint. ...
Kieran, K., Anderson, J. R., Dome, J. S., Ehrlich, P. F., Ritchey, M. L., Shamberger, R. C., . . . Davidoff, A. M. (2013). Is adrenalectomy necessary during unilateral nephrectomy for wilms tumor? A report from the childrens oncology group. Journal of Pediatric Surgery, 48(7), 1598-1603.. ...
adrenalectomy answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
Jen had Pituitary surgery by Dr. Shahinian 4/28/04, removed ACTH secreting corticotroph hyperplasia and prolactinoma. She was diagnosed by Dr. Theodore Friedman as cyclical pituitary Cushings. Her second Surgery 7/21/04 for infection resulted in neuralgia. She had a BLA in March 2006 as Corticol Hyperplasia returned and she now has possible Nelsons syndrome. Jen…
Ectopic adrenocorticotropic hormone (ACTH) production is an uncommon cause of Cushings syndrome and, rarely, the source can be a phaeochromocytoma. A 55-year-old man presented following an episode of presumed gastroenteritis with vomiting and general malaise. Further episodes of diarrhoea, joint pains and palpitations followed. On examination, he was hypertensive with no clinical features to suggest hypercortisolaemia. He was subsequently found to have raised plasma normetanephrines of 3.98 nmol/L (NR ,0.71) and metanephrines of 0.69 nmol/L (NR ,0.36). An adrenal CT showed a 3.8 cm right adrenal nodule, which was not MIBG-avid but was clinically and biochemically consistent with a phaeochromocytoma. He was started on alpha blockade and referred for right adrenalectomy. Four weeks later, on the day of admission for adrenalectomy, profound hypokalaemia was noted (serum potassium 2.0 mmol/L) with non-specific ST-segment ECG changes. He was also diagnosed with new-onset diabetes mellitus (capillary ...
Cardiac function was evaluated by ventricular function curves during the cardiovascular collapse observed in acute and chronic adrenal insufficiency. A progressive decline in peak cardiac work was observed in the acutely adrenalectomized cat (30% decrease at 1.8 hours and 50% at 3.5 hours after adrenalectomy). This impairment in cardiac work paralleled the decrease in mean arterial blood pressure which reached 50 mm Hg 3.5 hours after adrenalectomy. Cortisol and d-aldosterone, and the volume-expander, dextran, prevented a significant fall in mean arterial blood pressure and in peak cardiac work. When the mean arterial blood pressure of nonadrenalectomized cats was adjusted to follow the changes seen in adrenalectomized cats, a 49% depression in cardiac work resulted 3.5 hours after the initial decline in arterial blood pressure. The data suggest that the time course of the hypotension and presumed reduction in coronary perfusion pressure is sufficient to account for the large impairment in peak ...
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Laparoscopic adrenalectomy - a minimally invasive procedure that removes the adrenal glands through a tiny hole in the abdomen - can be safely performed in obese patients with Cushings syndrome, a retrospective study reports. The surgery resolved symptoms in 95% of cases, reducing cortisol level...
Genetic association studies hinge on definite clinical case definitions of the disease of interest. This is why more penetrant mutations were overrepresented in early multiple endocrine neoplasia 2 (MEN2) studies, whereas less penetrant mutations went underrepresented. Enrichment of genetic association studies with advanced disease may produce a flawed understanding of disease evolution, precipitating far-reaching surgical strategies like bilateral total adrenalectomy and 4-gland parathyroidectomy in MEN2. The insight into the natural course of the disease gleaned over the past 25 years caused a paradigm shift in MEN2: from the removal of target organs at the expense of greater operative morbidity to close biochemical surveillance and targeted resection of adrenal tumors and hyperplastic parathyroid glands ...
Learn and reinforce your understanding of Adrenal hormone synthesis inhibitors through video. Adrenal hormone synthesis inhibitors
CLINICAL HISTORY AND RADIOLOGY. The patient was a 52 year old male with a history of Cushings disease, initially diagnosed at the age of 18. At that time, his symptoms included increased weight, purple abdominal striae, diabetes mellitus, and polydipsia. He underwent a resection of a pituitary microadenoma at another hospital. However, due to persistently high cortisol levels following the surgery, he later underwent a bilateral adrenalectomy. Following the operation, he began hydrocortisone therapy, lost weight, and was able to maintain glucose control without diabetes medications. At the age of 32 his diabetes recurred, but he was able to maintain good glucose control up until age 51 at which time his HbA1C was greater than 7. He also had visual problems with significant reduction in right peripheral vision and moderate impairment in left. Testing revealed a greatly elevated serum ACTH at 5,082 pg/mL (normal is 9 - 46 pg/mL), but serum cortisol within normal limits 4 ug/dL. MRI scans found a ...
113.- ML.GALVE, V.CUERVAS-MONS, J.FIGUERAS, I.HERRERO, M.ATA, G.CLEMENTE, M.PRIETO, C.MARGARIT, A.BERNARDOS, F.CASAFONT. Incidence and outcome of the novo malignancies after liver transplantation. Transpl Proc 1999, 31:1275-1277. 114.- J. PUJOL, M. VILADRICH, A. RAFECAS, L. LLADÓ, A. GARCÍA-BARRASA, J. FIGUERAS, E. JAURRIETA. Laparoscopic adrenalectomy: review of initial 30 cases. Surgical Endoscopy 1999; 13-488-492. 115.- P.PARRILLA, F. SÁNCHEZ BUENO, J. FIGUERAS, E. JAURRIETA, J. MIR, C. MARGARIT, J. LÁZARO, L. HERRERA, M. GÓMEZ FLEITAS, E. VARÓ, E. VICENTE, R. ROBLES, P. RAMIREZ. Analysis of the complication of the piggy-back technique in 1.112 liver transplants. Transplantation 1999; 67:1214-1217.. 116.- A. DALMAU, A. SABATÉ, F. ACOSTA, L. GARCÍA HUETE, M. KOO, M. RECHE, A. RAFECAS, J. FIGUERAS, E. JAURRIETA. Comparative study of antifibrinolytic drugs in orthotopic liver transplantation. Transp Proc 1999; 31:2361-2362. 117.- D. PARÉS, J. FIGUERAS, A. RAFECAS, J. FABREGAT, J. ...
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Tumors of the adrenal cortex are reported in 2% of all autopsies, with the most common lesion being a benign adenoma (see the first image below). The common major pathologic entities of the adrenal gland that require surgical intervention are primary hyperaldosteronism (ie, Conn syndrome, see the second image below), Cushing syndrome, pheochr...
Learn about benign adrenal tumors and adrenal cancer treatment, such as an adrenalectomy, by endocrine surgeons at Brigham and Womens Hospital.
The Aldosteronoma Resolution Score (ARS) is currently the most accurate prediction model for complete resolution of hypertension after adrenalectomy, taking into account 4 preoperative clinical parame... more
Researchers from Germany looked at the clinical parameters that predict hypertension resolution following laparascopic adrenalectomy.
High levels of estrogen causes an increase in levels of cortisol-binding globulin which - you guessed it - binds cortisol in the blood. The amount of free cortisol available to enter the cell membranes and activate receptors inside the cell is now
TY - JOUR. T1 - Catecholamine-glucocorticoid interactions during surgical stress. AU - Udelsman, Robert. AU - Goldstein, David S.. AU - Loriaux, D. Lynn. AU - Chrousos, George P.. PY - 1987/12. Y1 - 1987/12. N2 - The stress response involves activation of the hypothalamic-pituitary adrenal axis and the sympathetic nervous system. To study the relative contributions of glucocorticoids, epinephrine, norepinephrine, and dopamine to homeostasis, we examined the effects of cortisol and epinephrine deficiency on the norepinephrine and dopamine responses to surgical stress in nonhuman primates. Adult male cynomolgus monkeys (n = 7-8/group)underwent bilateral or sham adrenalectomy and were maintained for 4 months on physiologic glucocorticoid (hydrocortisone phosphate, 32 mg/M2/day) and mineralocorticoid (DOCA pivalate, 1 mg/day) replacement, or placebo injections, respestively. The adrenalectomized monkeys were then stratified into three groups receiving subphysiologic (× 1 10), physiologic (×1), or ...
The effect of alterations in extracellular fluid volume (ECV) and solute concentration on excretion of urinary kallikrein was examined in conscious Sprague-Dawley rats. Animals were given infusions of either dextrose and water, saline, or albumin according to a variety of protocols. These were designed to evaluate possible relationships between excretion of kallikrein, volume, sodium, and potassium. A reproducible pattern of kallikrein excretion was noted in all volume expanded groups. This consisted of a short lived increase during the initial hour of expansion with a subsequent fall to lower levels than baseline and a gradual recovery. To define the role of aldosterone in these studies, an adrenalectomized group and a group of appropriately prepared sham controls were expanded with saline. Adrenalectomy did not effect this pattern. We postulate a tubular washout phenomenon as the etiology of these observations. Results of these studies fail to demonstrate a consistent relationship between ...
The adrenal glands are part of the endocrine system, which regulates hormone levels in the body. They are small, pyramid-shaped glands that rest on th...
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Brisbane adrenal surgeon Dr David Wilkinson specialises in adrenal conditions which are explained here: adrenalectomy - removal of an adrenal gland indicated in two main situations ...
Related Articles Minimally Invasive Adrenalectomy: Technical Aspects of the Laparoscopic and the Robotic Approach. Chirurgia (Bucur). 2020 Jan-Feb;115(1):80-88 Authors: Makkai-Popa ST, Pascotto B, Arru L ...
A list of 15 letter words that start with Ad in the enable censored word list. 11 words: adenocarcinomas adenohypophyses adenohypophysis adjustabilities administrations admirablenesses admissibilities adrenalectomies adventurousness adversarinesses advisablenesses...
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Adrenalectomy. *Tests *Dexamethasone suppression test. *ACTH stimulation test. *Captopril suppression test. *Fluid deprivation ...
Adrenalectomy. *Tests *Dexamethasone suppression test. *ACTH stimulation test. *Captopril suppression test. *Fluid deprivation ...
Shen WT, Lee J, Kebebew E, Clark OH, Duh QY (August 2006). "Selective use of steroid replacement after adrenalectomy: lessons ... Typically, a complete or total adrenalectomy is performed; however, a technique referred to as "cortical-sparing" can leave a ... Lee JE, Curley SA, Gagel RF, Evans DB, Hickey RC (December 1996). "Cortical-sparing adrenalectomy for patients with bilateral ... Adrenal Insufficiency: Following a bilateral adrenalectomy (left and right), the patient is no longer capable of secreting the ...
Nursing care after adrenalectomy or hypophysectomy. The American Journal of Nursing, 62(4), 84-86. Lubic, R.W. (1969). The ...
Adrenalectomy is the treatment of choice. Metyrapone may also be used for treatment. McCune-Albright syndrome is estimated to ...
Anías-Calderón, José; Verdugo-Díaz, Leticia; Drucker-Colín, René (2004). "Adrenalectomy and dexamethasone replacement on ...
"Trends in adrenalectomy: a recent national review". Surg Endosc. 24 (10): 2518-2526. doi:10.1007/s00464-010-0996-z. PMID ...
Nelson DH, Meakin JW, Thorn GW (March 1960). "ACTH-producing pituitary tumors following adrenalectomy for Cushing's syndrome". ... Aggarwal S, Yadav K, Sharma AP, Sethi V (June 2013). "Laparoscopic bilateral transperitoneal adrenalectomy for Cushing syndrome ...
The effect of adrenalectomy upon the total metabolism of the cat. The metabolic effect of adrenalectomy upon the urethanized ... Aub, Joseph C., Forman, Jonathan, & Bright, E. M. (1922). The effect of adrenalectomy upon the total metabolism of the cat. Am ... Aub, J. C., Bright, E. M., & Forman, J. (1922). The metabolic effect of adrenalectomy upon the urethanized cat. Am. J. Physiol ...
Role of adrenalectomy and adrenal-cortical hormones in oxygen poisoning. American Journal of Physiology. Legacy Content, 178(2 ...
At the point where abdominal CT scanning and pituitary fossa MRI show no clear abnormalities, adrenalectomy may be performed. ... The most common treatment for PPNAD is bilateral laparoscopic adrenalectomy; the process by which both adrenal glands are ...
Adrenalectomy is the removal of one or both adrenal glands. Apicoectomy is the surgical removal of tooth's root tip. ...
"Livedo Reticularis in a Patient with Pheochromocytoma Resolving After Adrenalectomy". The Journal of Clinical Endocrinology & ...
Unilateral adrenalectomy is the treatment of choice for unilateral PHA. Potential complications include hemorrhage and ...
Yukimura Y, Bray GA (1978). "Effects of adrenalectomy on body weight and the size and number of fat cells in the Zucker (fatty ... Obesity in rats was significantly reduced by adrenalectomy or hypophysectomy. The role of neuropeptide Y has gained substantial ...
In addition, adrenalectomies are used to diagnose the lesion and sometimes relieve pain. Because pseudocysts are closely ... an adrenalectomy or laproscopy may be used. Zadik, Yehuda; Aktaş, Alper; Drucker, Scott; Nitzan, Dorrit W. (2012). "Aneurysmal ...
... is also referred to as post adrenalectomy syndrome, a possible result of adrenalectomy performed for ... After a bilateral adrenalectomy is performed cortisol levels are no longer normal. This increases CRH production because it is ... The onset of the disease can occur up to 24 years after a bilateral adrenalectomy has been performed, with an average of up to ... A preventative measure that can be utilized is prophylactic radiotherapy when a bilateral adrenalectomy is being performed in ...
Following adrenalectomy, adrenaline disappears below the detection limit in the blood stream. Pharmacological doses of ... Low, or absent, concentrations of adrenaline can be seen in autonomic neuropathy or following adrenalectomy. Failure of the ...
Comparison of tissue accumulation of hexoestrol with response to bilateral adrenalectomy and oophorectomy". Lancet. 2 (7206): ...
Hypophysectomy Thyroidectomy Adrenalectomy List of surgeries by type v t e. ...
He was the first surgeon to perform an adrenalectomy to treat advanced malignancy. Brewer married Marjorie Hirst, who he met ...
Other robotic surgery he has been involved in include nephroureterectomy, pyeloplasty and adrenalectomy. He teaches robotics ...
Suspicious adrenal masses or those ≥4 cm are recommended for complete removal by adrenalectomy. Masses 1 cm (unless the TSH is ...
In people with a single benign tumor (adenoma), surgical removal (adrenalectomy) may be curative. This is usually performed ...
Studies have shown that corticosterone treatment and adrenalectomy reduces or upregulated hippocampal BDNF expression. ...
"The level and phosphorylation of Hsp70 in the rat liver cytosol after adrenalectomy and hyperthermia". Cell Biology ...
"ACTH-producing pituitary tumors following adrenalectomy for Cushing's syndrome". NELSON DH, MEAKIN JW, THORN GW. Diakses ...
Galante M, McCorkle HJ: Clinical evaluation of bilateral adrenalectomy and oophorectomy for advanced mammary carcinoma. Am J ...
She was managed successfully with right adrenalectomy, and the tumor histology was consistent with adrenal oncocytoma. Santos- ...
However, even after adrenalectomy, HSD2 neurons become activated by sodium deprivation, proving that MR activation is not ... All of these conditions, with the exception of adrenalectomy, cause a large elevation of circulating aldosterone. ... and adrenalectomy-also activate HSD2 neurons, although none do so to as great an extent as simply removing sodium from the diet ...
surgerydoor.co.uk: Adrenalectomy Surgery Encyclopedia: Adrenalectomy v t e v t e. ... Adrenalectomy (sometimes written as ADX for the procedure or resulting state) is the surgical removal of one or both (bilateral ... Complications from an adrenalectomy can include insufficient cortisol production, post-operative bleeding, damage to nearby ... adrenalectomy) adrenal glands. It is usually advised for patients with tumors of the adrenal glands. The procedure can be ...
Find out how adrenalectomy can impact the incidence of ESRD and mortality among patients with primary aldosteronism. ... Adrenalectomy. P MRA. Therapeutic Option. Crude Hazard Ratio (95% CI). P Adjusted Hazard Ratio (95% CI). P Competing Hazard ... After adrenalectomy, patients with APA had better long-term outcomes regarding progression to ESRD and mortality than ... Adrenalectomy Improves the Long-Term Risk of End-Stage Renal Disease and Mortality of Primary Aldosteronism. ...
See a list of publications about adrenalectomy by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine. ... Adrenalectomy. Rochester, Minn.: Mayo Foundation for Medical Education and Research. 2017.. *Economopoulos KP, et al. ... Laparoscopic versus robotic adrenalectomy: A comprehensive meta-analysis. International Journal of Surgery. 2017;38:95. ... Laparoscopic adrenal gland removal (adrenalectomy) patient information from Sages. Society of American Gastrointestinal and ...
Make research projects and school reports about Adrenalectomy easy with credible articles from our FREE, online encyclopedia ... Adrenalectomy. Definition. Adrenalectomy is the surgical removal of one or both of the adrenal glands. The adrenal glands are ... Adrenalectomy. Definition. Adrenalectomy is the surgical removal of one or both adrenal glands. The adrenal glands are paired ... With laparoscopy, adrenalectomy can be accomplished through four very small incisions.. Purpose. Adrenalectomy is usually ...
Laparoscopic adrenalectomy provides patients with a safe and effective way to remove a diseased or cancerous adrenal gland. ... Laparoscopic adrenalectomy is performed under a general anesthetic. The typical length of the operation is 3-4 hours. The ... Laparoscopic adrenalectomy is a minimally invasive technique, which provides patients with less discomfort and equivalent ... When compared to conventional open surgery, laparoscopic adrenalectomy has resulted in significantly less post-operative pain, ...
Treatments and Tools for Adrenalectomy. Find Adrenalectomy information, treatments for Adrenalectomy and Adrenalectomy symptoms ... Adrenalectomy - MedHelps Adrenalectomy Center for Information, Symptoms, Resources, ... I had a adrenalectomy 5 days ago. Now I am having symptoms of adrenal surge. Dr gave me Xa... ... my husband had a left adrenalectomy,2 days later we found him and he wouldnt wake up. his ... ...
Between March and June 1994 three adrenalectomies were performed via an endoscopic extraperitoneal approach. After creating a ... Adrenalectomy / instrumentation*. Aged. Female. Humans. Laparoscopes*. Male. Middle Aged. Paraneoplastic Endocrine Syndromes / ... Via these ports adrenalectomy was performed. Time of operation amount to 215, 290 and 330 min. No postoperative complications ... Between March and June 1994 three adrenalectomies were performed via an endoscopic extraperitoneal approach. After creating a ...
Jen had Pituitary surgery by Dr. Shahinian 4/28/04, removed ACTH secreting corticotroph hyperplasia and prolactinoma. She was diagnosed by Dr. Ted Friedman as cyclical pituitary Cushings. Her second Surgery 7/21/04 for infection resulted in neuralgia. She had a BLA in March 2006 as Corticol Hyperplasia returned and she now has possible Nelsons syndrome. Jen also has Thyroid Issues (Hashimotos, multiple nodules and entire thyroid removed 2003) and she is Growth Hormone Deficient (3/2006)
Care guide for Laparoscopic Adrenalectomy (Precare). Includes: possible causes, signs and symptoms, standard treatment options ... Laparoscopic adrenalectomy is surgery to remove all or part of your adrenal gland. It is usually done when a small tumor is ...
Keyword(s): adrenal vein, adrenalectomy, bleeding, Cushings disease, energy devices, Gelport, hand assistance, hand port, ...
Robotic Versus Laparoscopic Adrenalectomy. Introduction: With the advances in technology, there has been a recent interest in ... The aim of this study was to develop techniques of robotic lateral and posterior adrenalectomy and compare results to ... A number of reports has demonstrated the safety of robotic lateral adrenalectomy with scant comparison data. Nevertheless, the ... Methods and Procedures: Within a year, 15 patients underwent robotic and 20 patients laparoscopic adrenalectomy in an endocrine ...
Adrenalectomy may Help Patients With Mild Cushing Syndrome. A new study has found that patients with a mild form of Cushing ... Adrenalectomy Can Help In Ameliorating Cushing Syndrome. by Medindia Content Team on December 12, 2007 at 4:06 PM Research News ... Auchus said, "but we found that adrenalectomy can dramatically help some patients." Dr. Auchus said there are many caveats to ... Auchus research group analyzed the records of 24 patients who underwent adrenalectomy at UT Southwestern between 2003 and 2006 ...
In this study, we review our experience and strategies to reduce the cost of RA comparing it to Laparoscopic adrenalectomy (LA ... the use of robotic-assisted adrenalectomy (RA) has increased; however, many surgeons question its reported higher cost. ... Keywords: Anesthesia time; Cost of adrenalectomy; Da Vinci; Laparoscopic adrenalectomy; Procedure time; Robotic-assisted ... A cost-conscious approach to robotic adrenalectomy J Robot Surg. 2018 Dec;12(4):607-611. doi: 10.1007/s11701-018-0782-9. Epub ...
Adrenalectomy is surgery to remove one or both adrenal glands. These glands are on top of the kidneys. They make hormones that ... Perioperative complications of adrenalectomy-12 years of experience from a single center/teaching hospital and literature ... Open Adrenalectomy Technique. Medscape. Available at: https://emedicine.medscape.com/article/1895027-technique. Accessed ...
Factors associated with prolonged hospital stay after laparoscopic adrenalectomy. *José Ignacio Rodríguez-Hermosa. ORCID: orcid ... Coste T, Caiazzo R, Torres F, Vantyghem MC, Do Cao C, Douillard C, Pattou F (2017) Laparoscopic adrenalectomy by transabdominal ... Kazaure HS, Roman SA, Sosa JA (2011) Adrenalectomy in older Americans has increased morbidity and mortality: an analysis of ... Major P, Matlok M, Pedziwiatr M, Budzynski A (2012) Do we really need routine drainage after laparoscopic adrenalectomy and ...
... indication for adrenalectomy, partial versus total adrenalectomy, suspected versus confirmed metastatic disease. ... More From BioPortfolio on "Adrenalectomy for Solitary Adrenal Gland Metastases". *Related Companies*Related Events*Related ... The aim of this study is to compare retrospectively in case and control study, performing adrenalectomy, open or laparoscopic, ... Median survival was 16 months for patients who underwent adrenalectomy compared to 5 months for patients with documented ...
Adrenalectomy in dogs with adrenal gland tumors: 52 cases (2002-2008).. Massari F1, Nicoli S, Romanelli G, Buracco P, Zini E. ... To evaluate predictors of survival time in dogs undergoing adrenalectomy and identify risk factors associated with adrenal ... and vein thrombosis and when adrenalectomy was combined with an additional abdominal surgical intervention. On multivariate ...
Introduction Laparoscopic adrenalectomy (LA) is the procedure of choice for small benign adrenal tumors. In the absence of ... Laparoscopic Approach Adrenal Tumor Laparoscopic Adrenalectomy Adrenocortical Carcinoma Open Adrenalectomy These keywords were ... Laparoscopic adrenalectomy: the optimal surgical approach. J Laparoendosc Adv Surg Tech A 2001;11:409-413CrossRefPubMedGoogle ... Laparoscopic adrenalectomy: lessons learned from 100 consecutive procedures. Ann Surg 1997;226:238-246CrossRefPubMedGoogle ...
laparoscopic adrenalectomy group 1: tumor size as , 6 (group1). Procedure: Laparoscopic Adrenalectomy minimally invasive ... Laparoscopic adrenalectomy group2: tumor size ≥ 6 cm (group2). Procedure: Laparoscopic Adrenalectomy minimally invasive lateral ... Laparoscopic Adrenalectomy for Large Adrenal Tumors.. The safety and scientific validity of this study is the responsibility of ... Laparoscopic adrenalectomy is the treatment of choice for the benign tumor of less than 6 cm. However, this is an ongoing ...
J. K. Jacobs, R. E. Goldstein, and R. J. Geer, "Laparoscopic adrenalectomy: a new standard of care," Annals of Surgery, vol. ... A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushings Syndrome. Halit Diri,1 Fahri Bayram,1 Yasin Simsek,1 ... Due to the risks of surgical complications during pregnancy, few pregnant women with adrenal CS have undergone adrenalectomy to ... Y. M. Nakashima, Y. Itonaga, H. Inoue, and S. Takahashi, "Pulmonary edema after laparoscopic adrenalectomy in a pregnant ...
This Laparoscopic Adrenalectomy consultation is part of a series of consultations with surgical specialists at the University ... Home ▶ Medical Services ▶ Surgery ▶ What to Expect During Your Consultation ▶ Laparoscopic Adrenalectomy ... Doctor: The surgery is called a laparoscopic adrenalectomy. A laparoscopic, or minimally invasive, surgery involves specialized ... This hypothetical consultation about laparoscopic adrenalectomy for adrenal gland ademoma is presented for purposes of general ...
An adrenalectomy is the surgical removal of one or both of the adrenal glands and is used to treat cancers in the adrenal gland ... Adrenalectomy: Removal of the adrenal gland is known as an adrenalectomy. Currently, it is recommended that those with adrenal ... The hospital stay from an adrenalectomy is typically 3 to 5 days. Recovery from an adrenalectomy can take anywhere from 2 to 6 ... What is an adrenalectomy and how is it performed?. Adrenocortical carcinoma is a rare cancer affecting the outer layer of the ...
Comparison Between Posterior Retroperitoneoscopic Adrenalectomy and Laparoscopic Adrenalectomy (PRA). The safety and scientific ... Lateral Transperitoneal Adrenalectomy Versus Posterior Retroperitoneoscopic Adrenalectomy for Benign Adrenal Gland Disease: ... Since 1992, transabdominal LA(laparoscopic adrenalectomy) has been a standard method of adrenalectomy. This traditional method ... Randomized Controlled Trial Between PRA(Posterior Retroperitoneoscopic Adrenalectomy) and LA(Laparoscopic Adrenalectomy). ...
Laparoscopic adrenalectomy through four ports was performed according to the preoperative evaluation of the tumor size. During ... Primary adrenal leiomyosarcoma treated by laparoscopic adrenalectomy Leiomiosarcoma adrenal primario tratado con adrenalectomía ... However, reports about its feasibility have increased in the last years.10 Likewise, laparoscopic adrenalectomy is recommended ... 2 We describe a case of primary adrenal leiomyosarcoma which was treated by laparoscopic adrenalectomy. ...
... on this page of World Laparoscopy Hospital describe some of the essential steps of performing laparoscopic adrenalectomy. ... Laparoscopic partial adrenalectomy. From Jeschke et al., A showed the safety and efficacy of laparoscopic partial adrenalectomy ... Bilateral laparoscopic adrenalectomy. Bilateral adrenalectomy is provided to bilateral adrenal hyperplasia associated with ... Right adrenalectomy. Ports are located in the same mode left mirror image. Again, the fascia layer to invest in the right ...
Learn more about Adrenalectomy -- Open Surgery at Methodist Healthcare DefinitionReasons for ProcedurePossible ... Adrenalectomy is the removal of one or both adrenal glands. There is one adrenal gland on top of each kidney. The adrenal ... Trends in adrenalectomy rates, indications, and physician volume: A statewide analysis of 1,816 adreanlectomies. Surgery. 2007; ... The role of laparoscopic adrenalectomy for adrenal tumours of 6 cm or greater. Surg Endosc. 2008;22(3):617-621. ...
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome (AUSC). The safety and scientific validity of ... Adrenalectomy Versus Follow-up in Patients With Mild Hypercortisolism: a Prospective Randomized Controlled Trial. ... The aim of this study is to investigate if adrenalectomy for subclinical Cushings syndrome (mild hypercortisolism without ...
UW Health surgeons perform laparoscopic adrenalectomy, most commonly to remove tumors from the adrenal gland, which is ... With laparoscopic adrenalectomy, surgery occurs through three or four small incisions measuring less than 0.5 inches. ... Prior to the development of the procedure known as laparoscopic adrenalectomy, the removal of an adrenal gland consisted of a ... Surgical removal of an adrenal gland, or adrenalectomy, is most commonly performed for a tumor located within the adrenal gland ...
A null hypothesis tested the single question asked by this study: "Is surgical adrenalectomy superior to treatment with AG and ... We randomized 96 postmenopausal women with metastatic breast carcinoma to receive surgical adrenalectomy or medical therapy ... A randomized trial comparing surgical adrenalectomy with aminoglutethimide plus hydrocortisone in women with advanced breast ... as compared with 45 per cent of 29 women undergoing surgical adrenalectomy (P value not significant). Responses lasted a mean ...
Laparoscopic partial adrenalectomy. Biomedical Pharmacotherapy 56 (2002) suppl.1: 126s-131s. Martinez, D. G. Adrenalectomy ... Open adrenalectomy The surgeon may operate from any of four directions, depending on the exact problem and the patients body ... Adrenalectomy is usually performed by conventional (open) surgery; however, in selected patients, surgeons may use laparoscopy ... Robotic-assisted laparoscopic adrenalectomy. Urology 60 (December 2002): 1104-1107. Hawn, M. T., D. Cook, C. Deveney, and B. C ...
  • Adrenalectomy is usually advised for patients with tumors of the adrenal glands. (encyclopedia.com)
  • Researchers at UT Southwestern Medical Center have found that patients with a mild form of Cushing syndrome, a metabolic disorder caused by adrenal tumors, demonstrate substantial clinical improvement after adrenalectomy. (medindia.net)
  • Adrenalectomy in dogs with adrenal gland tumors: 52 cases (2002-2008). (nih.gov)
  • Laparoscopic adrenalectomy (LA) is the procedure of choice for small benign adrenal tumors. (springer.com)
  • Laparoscopic adrenalectomy for large solid cortical tumors without pre- or intraoperative evidence of malignancy is not contraindicated, and it is unlikely to have a deleterious effect on long-term outcome. (springer.com)
  • Laparoscopic Adrenalectomy for Large Adrenal Tumors. (clinicaltrials.gov)
  • Adrenalectomy is primarily done for tumors of the adrenal gland. (umms.org)
  • For many benign conditions, especially Conn's tumors and sporadic pheochromocytoma -- both of which are benign tumors that can secrete hormones that make the patient's blood pressure extremely high -- and for hormonally inactive tumors found while looking for some other condition, laparoscopic adrenalectomy is an excellent alternative. (umms.org)
  • The most common indicator for adrenalectomy is the presence of hormone-producing adrenal tumors. (laparoscopic.md)
  • To compare clinical results of LTA and PRA endoscopic adrenalectomies for tumors (termedia.pl)
  • Absolute contraindications for laparoscopic adrenalectomy are as follows: severe cardiopulmonary disease, locally advanced tumors, medically untreated pheochromocytoma, and uncontrolled coagulopathies. (websurg.com)
  • Objective: Systematic meta-analysis to determine the effect of adrenalectomy vs conservative follow-up on cardiovascular risk factors in patients with adrenal tumors and SCS. (endocrine-abstracts.org)
  • We included and extracted studies with at least five SCS patients with adrenal tumors undergoing adrenalectomy where outcomes of interest were measured before and after surgery. (endocrine-abstracts.org)
  • Objectives: Standard multi-port laparoscopic adrenalectomy (LA) is considered the gold standard for benign adrenal tumors. (pagepressjournals.org)
  • The objective was to evaluate and compare results of single-site transumbilical laparoendoscopic adrenalectomy with standard LA for adrenal tumors. (pagepressjournals.org)
  • Conclusions: Our results revealed that transumbilical approach for laparoendoscopic single-site adrenalectomy for adrenal tumors is a feasible and safe alternative to standard laparoscopic adrenalectomy. (pagepressjournals.org)
  • Laparoscopic adrenalectomy (LA) is considered as a best approach for the treatment for adrenal tumors. (sch.ac.kr)
  • If the hormonal activity of adrenal tumors is not confirmed, the tumor should be considered functional when accompanied by related symptoms and an adrenalectomy should be performed. (kjco.org)
  • In particular, for benign adrenal tumors, laparoscopic adrenalectomy is considered a priority as reduced blood loss, shorter hospital stays, and faster recovery times are expected, compared with open surgery [ 1 - 4 ]. (kjco.org)
  • First, if adrenal tumors were identified with accompanying symptoms such as hypertension using radiological examination, hormonal activity was confirmed with hormonal work-ups and an adrenalectomy was performed. (kjco.org)
  • Adrenalectomy (sometimes written as ADX for the procedure or resulting state) is the surgical removal of one or both (bilateral adrenalectomy) adrenal glands. (wikipedia.org)
  • Adrenalectomy is the surgical removal of one or both adrenal glands. (encyclopedia.com)
  • Methods and Procedures: Within a year, 15 patients underwent robotic and 20 patients laparoscopic adrenalectomy in an endocrine surgical program. (sages.org)
  • On the basis of results of univariate analysis, survival time was significantly shorter for dogs with adenocarcinoma, tumor major axis length ≥ 5 cm, metastasis, and vein thrombosis and when adrenalectomy was combined with an additional abdominal surgical intervention. (nih.gov)
  • Laparoscopic adrenalectomy: the optimal surgical approach. (springer.com)
  • The purpose of this study is to compare two surgical methods of adrenalectomy. (clinicaltrials.gov)
  • Described the first laparoscopic adrenalectomy (al), this minimally invasive surgical approach almost replaced open adrenalectomy in handling small and medium-adrenal lesions. (laparoscopyhospital.com)
  • Surgical removal of an adrenal gland, or adrenalectomy, is most commonly performed for a tumor located within the adrenal gland that is either producing too many hormones or is potentially cancerous. (uwhealth.org)
  • A randomized trial comparing surgical adrenalectomy with aminoglutethimide plus hydrocortisone in women with advanced breast cancer. (nih.gov)
  • We randomized 96 postmenopausal women with metastatic breast carcinoma to receive surgical adrenalectomy or medical therapy with an adrenal inhibitor, aminoglutethimide (AG), plus replacement hydrocortisone. (nih.gov)
  • Of 40 evaluable women treated with AG and hydrocortisone, 53 per cent had objective responses, as compared with 45 per cent of 29 women undergoing surgical adrenalectomy (P value not significant). (nih.gov)
  • A null hypothesis tested the single question asked by this study: "Is surgical adrenalectomy superior to treatment with AG and hydrocortisone? (nih.gov)
  • Rejection at significance levels of P = 0.01 and P = 0.07 for differences of 20 per cent and 10 per cent, respectively, suggested that medical therapy with AG and hydrocortisone may be logically chosen in place of surgical adrenalectomy. (nih.gov)
  • Nowadays, laparoscopic adrenalectomy is the gold standard in the management of adrenal gland tumours qualified for surgical treatment. (termedia.pl)
  • Laparoscopic adrenalectomy is a surgical technique used to remove the adrenal gland without making a big incision. (umms.org)
  • Adrenalectomy is the surgical removal of all or part of an adrenal gland. (laparoscopic.md)
  • Laparoscopic adrenalectomy has become the gold standard of surgical treatment for benign adrenal masses. (termedia.pl)
  • adrenalectomy - ad·re·nal·ec·to·my (ə drē nə lĕkʹtə mē) n. pl. ad·re·nal·ec·to·mies Surgical excision of one or both of the adrenal glands. (enacademic.com)
  • The surgical procedure of adrenal gland removal is known as adrenalectomy and is indicated in patients with benign or malignant tumour like mass within the adrenal glands. (drmichaelsoo.com.au)
  • Further, two or three small incisions are made through which surgical instruments are inserted to perform the adrenalectomy procedure. (drmichaelsoo.com.au)
  • In this study, we reviewed 16 cases of adrenalectomy, focusing specifically on the surgical outcomes and clinical courses. (kjco.org)
  • In this study, we reviewed several cases of adrenalectomy, focusing on the surgical outcomes and clinical course. (kjco.org)
  • Laparoscopic adrenalectomy is a minimally invasive technique, which provides patients with less discomfort and equivalent results when compared to the larger incision required with traditional open surgery. (hopkinsmedicine.org)
  • When compared to conventional open surgery, laparoscopic adrenalectomy has resulted in significantly less post-operative pain, a shorter hospital stay, earlier return to work and daily activities, a more favorable cosmetic result and outcomes identical to that of open surgery. (hopkinsmedicine.org)
  • Laparoscopic adrenalectomy is surgery to remove all or part of your adrenal gland. (drugs.com)
  • Adrenalectomy is surgery to remove one or both adrenal glands. (epnet.com)
  • The patients, underwent laparoscopic adrenalectomy, were also classified into group A (1-25), B (26-50), C (51-75), and D (76-102) according to the chronological order of their surgery in order to evaluate the learning curve. (clinicaltrials.gov)
  • Laparoscopic adrenalectomy is the first line treatment of choice in patients with cortisol-secreting adrenal adenomas, while medical treatment is suggested when surgery is contraindicated [ 7 , 8 ]. (hindawi.com)
  • The surgery is called a laparoscopic adrenalectomy. (ucsd.edu)
  • UW Health endocrine surgeons in Madison, Wisconsin, perform laparoscopic adrenalectomy, also known as minimally-invasive adrenal surgery. (uwhealth.org)
  • With laparoscopic adrenalectomy, surgery occurs through three or four small incisions measuring less than 0.5 inches. (uwhealth.org)
  • Budzyński A, Pędziwiatr M, Matłok M, Hubalewska-Dydejczyk A, Matyja M, Buziak-Bereza M. Preliminary experience with transperitoneal single incision laparoscopic surgery adrenalectomy. (termedia.pl)
  • From February until May 2010, 7 patients treated in the 2nd Department of Surgery of the Medical College of Jagiellonian University were qualified for SILS adrenalectomy. (termedia.pl)
  • The indications for laparoscopic adrenalectomy are the same as for open surgery, except in cases of confirmed adrenocortical carcinomas. (websurg.com)
  • This is a live demonstration of a left adrenalectomy recorded during the Minimally Invasive Endocrine Surgery Course, which was held at IRCAD in May 2016. (websurg.com)
  • Laparoscopic adrenalectomy is an attractive alternative to open surgery in children as it is associated with less operative pain and a rapid resumption of diet and shorter operative time. (websurg.com)
  • Comparison of laparoscopic versus open adrenalectomy: results from American College of Surgeons-National Surgery Quality Improvement Project. (semanticscholar.org)
  • Preoperative cross-sectional imaging allows for avoidance of unnecessary adrenalectomy during RCC surgery. (semanticscholar.org)
  • The aim of this study was to report a national experience of adrenalectomy with particular attention to predictive factors for postoperative complications, conversion from endoscopic to open surgery and length of hospital stay. (lu.se)
  • Methods: Adrenalectomies reported in the Scandinavian Quality Register for Thyroid, Parathyroid and Adrenal Surgery (SQRTPA) 2009-2014 were included. (lu.se)
  • The aim of this study is to develop a porcine model of adrenalectomy for teaching and advancing the technique applicable to human surgery. (elsevier.com)
  • Adrenalectomy is a topic covered in the Pediatric Surgery NaT . (pedsurglibrary.com)
  • APSA Webapp, www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829542/all/Adrenalectomy. (pedsurglibrary.com)
  • Today, with the technique known as minimally invasive surgery, removal of the adrenal gland (also known as "laparoscopic adrenalectomy") can be performed through three or four 1/4-1/2 inch incisions. (southwestsurgical.com)
  • A bilateral adrenalectomy is surgery to remove both adrenal glands . (cancer.ca)
  • Although minimally invasive adrenal surgery replaced the open Adrenalectomy , SILS Adrenalectomy is a step forward technique that improves the cosmesis , decreases acsess related morbidity , and increases the postoperative recovery. (idexlab.com)
  • Adrenalectomy can be performed either with laparoscopic technique or open surgery. (drmichaelsoo.com.au)
  • The main types of adrenalectomy are keyhole surgery (laparoscopic) and open surgery. (advancesurgical.com.au)
  • Today, with minimally invasive surgery, removal of the adrenal gland is done as a laparoscopic adrenalectomy. (advancesurgical.com.au)
  • Compared to laparoscopic adrenalectomy, open surgery resulted in a statistically significantly longer operating time, increased operative blood loss, and a longer postoperative hospital stay. (kjco.org)
  • In addition, we suggest that a laparoscopic adrenalectomy is superior to an open adrenalectomy in terms of recovery after surgery, despite the small number of cases evaluated. (kjco.org)
  • Open adrenalectomy should be considered following comprehensive consideration of the patient's condition, such as accompanying surgery or metastatic cancer. (kjco.org)
  • Because of the small size and retroperitoneal location of the adrenal glands, adrenalectomy prior to the introduction of laparoscopic surgery required a large laparotomy. (kjco.org)
  • We describe the demographic composition of the cases and our findings focused on three topics: (1) the relationship between the hormonal activity of the adrenal tumor and the indication for surgery, (2) comparison of the clinical outcomes between laparoscopic and open adrenalectomy, and (3) conditions that require an open adrenalectomy. (kjco.org)
  • Your surgeon can help you decide whether an adrenal tumor is best removed with laparoscopic adrenalectomy, retroperitoneoscopic adrenalectomy or the traditional open adrenalectomy. (uwhealth.org)
  • One of the early adaptors of the approach, Tobias Carling, MD, PhD, FACS, performs a right posterior retroperitoneoscopic adrenalectomy on a patient that presented with subclinical Cushing's syndrome. (jomi.com)
  • Posterior retroperitoneoscopic adrenalectomy (PRA) allows the surgeon to approach the adrenal gland through the back rather than the more traditional laparoscopic transabdominal adrenalectomy (LTA) approach. (jomi.com)
  • Type of procedure included 11 lateral transabdominal and 4 posterior retroperitoneal adrenalectomy in the robotic versus 13 lateral transabdominal and posterior retroperitoneal in the laparoscopic group (p=NS). (sages.org)
  • Prior to the development of the procedure known as laparoscopic adrenalectomy, the removal of an adrenal gland consisted of a moderate to large incision and a hospital stay of three to seven days. (uwhealth.org)
  • Adrenalectomy remains overused in populations that are unlikely to benefit from the procedure," the authors concluded. (renalandurologynews.com)
  • Although in laparoscopic adrenalectomy the approach is minimally invasive, the procedure is challenging. (uzh.ch)
  • For those carefully selected patients who are well-suited for the procedure, people who undergo laparoscopic adrenalectomy have done much better than those receiving the standard, "open" operations, with a much quicker return to normal activity, a shorter hospital stay, less need for pain medication, and a markedly lower incidence of complications. (umms.org)
  • Patients with adrenal disease should be referred to surgeons based on adrenalectomy volume regardless of specialty, but most endocrine surgeons that perform adrenalectomy are high-volume for the procedure. (ovid.com)
  • According to recent studies, robotic adrenalectomy has proven to be superior to laparoscopic adrenalectomy, with a reduction of blood loss during procedure and a reduced operative time. (websurg.com)
  • With increasing experience with laparoscopic adrenalectomy, this approach has become the procedure of choice for the majority of patients requiring adrenalectomy. (panafrican-med-journal.com)
  • CONCLUSION: SILS Adrenalectomy is a safe procedure for a benign adrenal lesion in experienced hands. (idexlab.com)
  • The surgeon uses a combination of blood and urine tests, CT scans and sometimes Magnetic Resonance Imaging before recommending the final adrenalectomy procedure. (advancesurgical.com.au)
  • Laparoscopic adrenalectomy is a safe and effective procedure and should help hasten postoperative recovery and may save the costs of hospitalization . (bvsalud.org)
  • After adrenalectomy, patients with APA had better long-term outcomes regarding progression to ESRD and mortality than hypertensive controls, but MRA treatments did not significantly affect outcome. (medscape.com)
  • Conclusion: This initial study shows that robotic adrenalectomy is equivalent to the laparoscopic approach regarding peri-operative outcomes, with better visualization and easier manipulation. (sages.org)
  • However, this is an ongoing debate that exact cut-off value of tumor size for LA. The aim of this study was to assess whether the size of the adrenal tumor affects preoperative and postoperative outcomes in patients undergoing laparoscopic transperitoneal adrenalectomy as well as to evaluate the learning curve. (clinicaltrials.gov)
  • Among those, PRA(posterior retroperitoneal adrenalectomy) has showed good outcomes in many institutes. (clinicaltrials.gov)
  • Objective: To systematically review all relevant literature comparing oncologic, perioperative, and quality-of-life (QoL) outcomes for locally advanced RCC managed with RN with or without concomitant adrenalectomy or LND. (diva-portal.org)
  • Conclusions: There is insufficient evidence to draw any conclusions on oncologic outcomes for patients having concomitant LND or ipsilateral adrenalectomy compared with patients having RN alone for cT3-T4N0M0 RCC. (diva-portal.org)
  • Previous associations between surgeon volume with adrenalectomy outcomes examined only a sample of procedures. (ovid.com)
  • We performed an analysis of all adrenalectomies performed in New York state to assess the effect of surgeon volume and specialty on clinical outcomes. (ovid.com)
  • Single center outcomes of laparoscopic transperitoneal lateral adrenalectomy--Lessons learned after 500 cases: A retrospective cohort study. (semanticscholar.org)
  • Medical charts of 41 laparoscopic and 39 open adrenalectomy patients were reviewed Baseline characteristics and outcomes of treatment were compared between these two patient groups, using univariable statistical tests and multivariable statistical procedures . (bvsalud.org)
  • Steroid medications may not be needed or may be discontinued in a few months to a year after unilateral adrenalectomy, but lifelong replacement therapy will be needed after bilateral adrenalectomy. (tabers.com)
  • Five female pigs weighing 10-20 kg underwent bilateral adrenalectomy by the lateral approach using endotracheal intubation. (elsevier.com)
  • Four years ago, I had a bilateral adrenalectomy. (lifewithcushings.com)
  • Of course, I thought having a bilateral adrenalectomy would quickly solve all health issues and I would go on to live a healthy, normal life, but that has been anything but the truth. (lifewithcushings.com)
  • Hello Dainelle, I had Cushing's and had a bilateral adrenalectomy two years ago. (lifewithcushings.com)
  • A bilateral adrenalectomy may be done through a cut in the abdomen or lower back above the hip (called an open bilateral adrenalectomy). (cancer.ca)
  • my husband had a left adrenalectomy,2 days later we found him and he wouldn't wake up. (medhelp.org)
  • Procedures were performed using transperitoneal access with the patient lying on the right side for left adrenalectomy and on the left side for right adrenalectomy (Figure 1). (termedia.pl)
  • Hypercortisolaemia persisted after left adrenalectomy. (bioscientifica.com)
  • Single-incision laparoscopic left Adrenalectomy . (idexlab.com)
  • We report our first experience with single- incision transperitoneal left Adrenalectomy in a patient with Conns' syndrome. (idexlab.com)
  • CASE: A 46-year-old female patient with a diagnosis of Conns' syndrome underwent single- incision transperitoneal laparoscopic left Adrenalectomy . (idexlab.com)
  • With laparoscopy, adrenalectomy can be accomplished through four very small incisions. (encyclopedia.com)
  • 1 ] in 1992, laparoscopy has been widely used for adrenalectomy. (kjco.org)
  • Gagner M, Lacroix A, Bolte E. Laparoscopic adrenalectomy in Cushing's syndrome and pheochromocytoma. (springer.com)
  • I am 11 months post op adrenalectomy due to a functional tumor that caused my Cushing's syndrome. (csrf.net)
  • Adrenalectomy in patients with cortisol-producing adrenal adenomas results in excellent improvement in the symptoms of Cushing's syndrome and improves patient quality of life. (seekhealthz.com)
  • In this study, we review our experience and strategies to reduce the cost of RA comparing it to Laparoscopic adrenalectomy (LA). Since May of 2010, 122 consecutive patients underwent minimally invasive adrenalectomy (58 RAs and 64 LA) by a high-volume adrenal surgeon at our institution. (nih.gov)
  • In this key lecture, Dr. Cherian outlines minimally invasive adrenalectomy. (websurg.com)
  • Minimally Invasive Adrenalectomy for Adrenocortical Carcinoma: Five-Year Trends and Predictors of Conversion. (uchicago.edu)
  • Coste T, Caiazzo R, Torres F, Vantyghem MC, Do Cao C, Douillard C, Pattou F (2017) Laparoscopic adrenalectomy by transabdominal lateral approach: 20 years of experience. (springer.com)
  • Since 1992, transabdominal LA(laparoscopic adrenalectomy) has been a standard method of adrenalectomy. (clinicaltrials.gov)
  • Background The aim of this study was to compare outcome measures between conventional transabdominal laparoscopic Adrenalectomy and single- incision laparoscopic Adrenalectomy (SILA). (idexlab.com)
  • One is called PRA(posterior retroperitoneal adrenalectomy), which is performed through 3 or 4 holes at patient's back. (clinicaltrials.gov)
  • We previously reported our initial experience with laparoendoscopic single-site (LESS) retroperitoneal partial adrenalectomy using a custom-made single-port device and conventional straight laparoscopic instruments. (scipedia.com)
  • Between December 2010 and February 2012, LESS retroperitoneal partial adrenalectomies were performed in 11 patients. (scipedia.com)
  • Our results clearly demonstrate that LESS retroperitoneal partial adrenalectomy can be performed safely and effectively using a custom-made single-access platform and standard laparoscopic instruments. (scipedia.com)
  • Fifth, adrenalectomy significantly affected the retroperitoneal and subcutaneous fat depots but not the epididymal fat depot. (elsevier.com)
  • Sixth, adrenalectomy decreased fat cell number in retroperitoneal and subcutaneous fat depots, but this was much less evident in the epididymal fat depot. (elsevier.com)
  • Laparoscopic adrenalectomy can be done for all patients with adrenal tumours regardless of tumour size, even it needs more time for large tumour but appears to be safe and feasible when performed by experienced surgeons. (panafrican-med-journal.com)
  • Background: Current practice patterns for adrenalectomy among endocrine surgeons is a limited area of study. (uab.edu)
  • Here we survey relatively junior endocrine surgeons regarding educational experiences in adrenalectomy and correlate these with current practice. (uab.edu)
  • Complications from an adrenalectomy can include insufficient cortisol production, post-operative bleeding, damage to nearby organs, and post-operative infection. (wikipedia.org)
  • In the current study, Dr. Auchus' research group analyzed the records of 24 patients who underwent adrenalectomy at UT Southwestern between 2003 and 2006 because of abnormally high cortisol production. (medindia.net)
  • Adrenalectomy abolishes and cortisol restores naloxone's beneficial effects on cardiovascular function and survival in canine hemorrhagic shock. (biomedsearch.com)
  • abstract = "Laparoscopic adrenalectomy has been successfully performed and described in humans. (elsevier.com)
  • Perioperative complications of adrenalectomy-12 years of experience from a single center/teaching hospital and literature review. (epnet.com)
  • Chen Y, Scholten A, Chomsky-Higgins K, Nwaogu I, Gosnell JE, Seib C, Shen WT, Suh I, Duh QY (2018) Risk factors associated with perioperative complications and prolonged length of stay after laparoscopic adrenalectomy. (springer.com)
  • Additionally, medical treatment should be administered preoperatively to decrease the likelihood of complications that occur due to adrenalectomy in patients with severe CS. (hindawi.com)
  • In this topic paper we will address the most frequently encountered complications of adrenalectomy: vascular injuries, injuries of the bowel, pleural tears, and injuries to the liver, spleen and pancreas. (uzh.ch)
  • Therefore, it's the surgeon's obligation to be aware of the possible complications he might encounter during laparoscopic adrenalectomy. (uzh.ch)
  • What are the risks and complications of adrenalectomy? (drchrislehane.com.au)
  • One hundred two patients with pheochromocytoma treated at a single institution since the introduction of laparoscopic adrenalectomy. (uchicago.edu)
  • Median survival was 16 months for patients who underwent adrenalectomy compared to 5 months for patients with documented adrenal metastases treated non surgically. (bioportfolio.com)
  • All extremes meticulously padded and attached as described above transperitoneal adrenalectomy to avoid injury neuromuscular. (laparoscopyhospital.com)
  • After preoperative metyrapone therapy, she underwent a successful unilateral laparoscopic adrenalectomy at 14-week gestation. (hindawi.com)
  • The various techniques of adrenalectomy, preoperative work-up, and indications are described in this lecture. (websurg.com)
  • Under the general anesthesia, operation was performed on a 34-year-old male, who was diagnosed as primary aldosteronism caused by aldosterone producing adenoma and we have experienced the anesthetic management of unilateral adrenalectomy during perioperative periods. (koreamed.org)
  • Adrenalectomy for Primary Aldosteronism: Significant Variability in Work-Up Strategies and Low Guideline Adherence in Worldwide Daily Clinical Practice. (urotoday.com)
  • Objectives:Current clinical guidelines of primary aldosteronism recommend adrenalectomy (AdX) for unilateral primary aldosteronism based on the studies showing the potential superiority of AdX over the medical treatment. (elsevier.com)
  • Today, laparoscopic removal of the adrenal gland (known as "laparoscopic adrenalectomy") is possible with the surgeon making three or four ¼- to ½ -inch incisions. (drashishbhanot.com)
  • Between March and June 1994 three adrenalectomies were performed via an endoscopic extraperitoneal approach. (biomedsearch.com)
  • Endoscopic adrenalectomy was performed in 513 (77.8%) operations and almost half of these were robotic assisted. (lu.se)
  • Here we describe a pregnant woman diagnosed with CS who underwent a successful unilateral laparoscopic adrenalectomy. (hindawi.com)
  • A number of reports has demonstrated the safety of robotic lateral adrenalectomy with scant comparison data. (sages.org)
  • The aim of this study was to develop techniques of robotic lateral and posterior adrenalectomy and compare results to conventional laparoscopic approach. (sages.org)
  • Robotic-assisted adrenalectomy. (nih.gov)
  • Robotic-assisted adrenalectomy: what advantages compared to lateral transperitoneal laparoscopic adrenalectomy? (semanticscholar.org)
  • Early experience with laparoscopic approach for adrenalectomy. (springer.com)
  • If a noncancerous (benign) adrenal tumor or adrenal cancer is discovered, you may require an adrenalectomy (uh-dree-nul-EK-tuh-me) to remove the adrenal gland that has the tumor. (pharmacypedia.org)
  • Laparoscopic adrenalectomy is usually indicated for non-cancerous (benign) adrenal tumours. (drmichaelsoo.com.au)
  • Introduction: Patients with subclinical Cushing s syndrome (SCS) present with increased cardiovascular morbidity and mortality, however, the beneficial effect of adrenalectomy on cardiovascular risk factors is uncertain. (endocrine-abstracts.org)
  • Bray, GA, Stern, JS & Castonguay, TW 1992, ' Effect of adrenalectomy and high-fat diet on the fatty Zucker rat ', American Journal of Physiology - Endocrinology and Metabolism , vol. 262, no. 1 25-1. (elsevier.com)
  • The effects of adrenalectomy and adrenal enucleation on liquid gastric emptying were studied in male Wistar rats that were adrenalectomized, adrenal enucleated (AE) or sham operated (SH). (scielo.br)
  • This study was therefore designed to examine the effects of adrenalectomy and adrenal enucleation on liquid gastric emptying (GE) in rats. (scielo.br)
  • We tested the effects of adrenalectomy, chronic exposure to the corticosterone synthesis inhibitor metyrapone (100 mg/kg, s.c., twice daily), acute exposure to metyrapone, acute intracerebroventricular injections of CRF (0.3 and 1.0 μg), and intracerebroventricular injections of the CRF antagonist α-helical CRF (3 and 10 μg). (jneurosci.org)
  • Several conclusions can be drawn about the effects of adrenalectomy, high-fat diets, and their interaction in the Zucker fatty rat. (elsevier.com)
  • The advantages of laparoscopic adrenalectomy include less postoperative pain, a shorter hospitalization period, minimal scar, reduced chronic pain from nerve injury, minimal risk of developing hernia, and a fast recovery with a much quicker return to normal activity. (drmichaelsoo.com.au)
  • Although several studies have found an increased survival in patients who undergo resection of solitary adrenal metastases the indications for adrenalectomy in cases of metastatic adrenal tumor remain controversial. (bioportfolio.com)
  • To evaluate predictors of survival time in dogs undergoing adrenalectomy and identify risk factors associated with adrenal gland tumor metastasis and vein thrombosis. (nih.gov)
  • Laparoscopic adrenalectomy is the treatment of choice for the benign tumor of less than 6 cm. (clinicaltrials.gov)
  • Stanley A. Yap, MD, of the University of Toronto, and colleagues identified 5,135 patients who underwent radical nephrectomy between 1995 and 2004, and used pathology reports to assess ipsilateral adrenalectomy and tumor involvement of the adrenal gland. (renalandurologynews.com)
  • Is adrenalectomy necessary during unilateral nephrectomy for Wilms Tumor? (gwu.edu)
  • Second, an adrenalectomy was performed regardless of the hormonal work-up result if there were symptoms that affected daily life, such as worsening hypertension, and a confirmation of an adrenal tumor by radiologic examination. (kjco.org)
  • Third, adrenalectomy was performed when the size of adrenal tumor had substantially increased at follow-up. (kjco.org)
  • MATERIALS AND METHODS The records of 511 patients undergoing radical nephrectomy with ipsilateral adrenalectomy for renal cell carcinoma at our medical center between 1986 and 1998 were reviewed. (semanticscholar.org)
  • Materials and methods: One hundred consecutive adrenalectomies from 93 patients, performed between March 2009 and June 2017, were laparoscopically excised: 59 by standard multi-port LA (group 1) and 41 by transumbilical laparoendoscopic single-site adrenalectomy (group 2). (pagepressjournals.org)
  • Methods: An electronic survey was sent to recent AAES-accredited fellowships graduates (2014-2019), querying adrenalectomy volume and approaches during fellowship and current practice patterns. (uab.edu)
  • A case-controlled study of laparoscopic compared with open lateral adrenalectomy. (springer.com)
  • Comparison of open posterior versus transperitoneal laparoscopic adrenalectomy. (springer.com)
  • Laparoscopic versus open posterior adrenalectomy: a case-control study of 100 patients. (springer.com)
  • Currently, it is recommended that those with adrenal cancer undergo an open adrenalectomy, in which the surgeon accesses the adrenal gland through an incision in the abdomen or back. (oncolink.org)
  • Comparative study of laparoscopic and open adrenalectomy. (semanticscholar.org)
  • When performing an open adrenalectomy your surgeon may choose from three different approaches: anterior, posterior, and thoracoabdominal. (drmichaelsoo.com.au)
  • Up to 5% of laparoscopic surgeries may be converted to an open adrenalectomy. (advancesurgical.com.au)
  • An open adrenalectomy starts with a 15 to 30 cm incision. (advancesurgical.com.au)
  • How is open adrenalectomy performed? (drchrislehane.com.au)
  • How is the posterior approach to open adrenalectomy performed? (drchrislehane.com.au)
  • A laparoscopic versus open adrenalectomy in Ramathibodi Hospital. (bvsalud.org)
  • To compare the results of laparoscopic adrenalectomy with those of open adrenalectomy in Ramathibodi Hospital . (bvsalud.org)
  • Based on the above rationale, we have performed laparoscopic or open adrenalectomy for the past 10 years. (kjco.org)
  • If the adrenalectomy is on the left side of the body, the surgeon gently moves past the spleen, tail of the pancreas, and part of the colon. (advancesurgical.com.au)
  • Although porcine and human adrenal anatomy differ in some details the pig constitutes an excellent model for the development of the technical experience required to perform adrenalectomy in humans. (elsevier.com)
  • Retroperitoneoscopic and laparoscopic partial adrenalectomies were also excluded from the study. (clinicaltrials.gov)
  • Adrenalectomy: Removal of the adrenal gland is known as an adrenalectomy. (oncolink.org)