AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaHealth CareGeographicals
Administration, OralDrug Administration ScheduleInjections, IntravenousUnited States Food and Drug AdministrationDrug Administration RoutesDose-Response Relationship, DrugRats, Sprague-DawleyTime FactorsAdministration, IntranasalRats, WistarInjections, IntraperitonealDisease Models, AnimalInjections, SubcutaneousAdministration, RectalLiverMice, Inbred C57BLBiological AvailabilityInjections, IntramuscularAdministration, TopicalInfusions, IntravenousHalf-LifeAdministration, IntravenousDrug InteractionsArea Under CurveInjections, IntraventricularMice, Inbred BALB CRats, Inbred StrainsAdministration, CutaneousTissue DistributionDogsDouble-Blind MethodCross-Over StudiesTreatment OutcomeBlood PressureAdministration, SublingualBrainAdministration, InhalationKidneyInfusions, ParenteralBody WeightRandom AllocationBehavior, AnimalDrug ToleranceMorphineRecombinant ProteinsPlant ExtractsInjectionsAnalysis of VarianceInjections, SpinalOrgan SizeMetabolic Clearance RateChromatography, High Pressure LiquidRNA, MessengerRabbitsMice, Inbred ICRLungRats, Inbred F344Analgesics, OpioidSelf AdministrationEthanolHeart RatePregnancyEstradiolMotor ActivityAntineoplastic AgentsDrug CombinationsMice, KnockoutHemodynamicsMice, Inbred StrainsDrug Evaluation, PreclinicalAnalgesicsDrug Therapy, CombinationEnzyme InhibitorsInjections, Intra-ArterialAdministration, BuccalSpleenPiperidinesProdrugsAntibodies, MonoclonalIntestinal AbsorptionBlood GlucoseDrug ApprovalAnti-Inflammatory Agents, Non-SteroidalDrug SynergismCocaineNaloxoneEatingUnited StatesDopamineGenetic TherapyNitric OxideCytokinesHydrocortisoneAbsorptionCells, CulturedLipopolysaccharidesImmunohistochemistryDelayed-Action PreparationsInsulinPain Measurement
Administration, Oral
The giving of drugs, chemicals, or other substances by mouth.
Drug Administration Schedule
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Injections, Intravenous
Injections made into a vein for therapeutic or experimental purposes.
United States Food and Drug Administration
An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.
Drug Administration Routes
The various ways of administering a drug or other chemical to a site in a patient or animal from where the chemical is absorbed into the blood and delivered to the target tissue.
Dose-Response Relationship, Drug
The relationship between the dose of an administered drug and the response of the organism to the drug.
Rats, Sprague-Dawley
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
Time Factors
Elements of limited time intervals, contributing to particular results or situations.
Administration, Intranasal
Delivery of medications through the nasal mucosa.
Rats, Wistar
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Injections, Intraperitoneal
Forceful administration into the peritoneal cavity of liquid medication, nutrient, or other fluid through a hollow needle piercing the abdominal wall.
Disease Models, Animal
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Injections, Subcutaneous
Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.
Administration, Rectal
The insertion of drugs into the rectum, usually for confused or incompetent patients, like children, infants, and the very old or comatose.
Liver
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
Mice, Inbred C57BL
Biological Availability
The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
Injections, Intramuscular
Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it.
Administration, Topical
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
Infusions, Intravenous
The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.
Half-Life
The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.
Administration, Intravenous
Delivery of substances through VENIPUNCTURE into the VEINS.
Drug Interactions
The action of a drug that may affect the activity, metabolism, or toxicity of another drug.
Area Under Curve
A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)
Injections, Intraventricular
Injections into the cerebral ventricles.
Mice, Inbred BALB C
Rats, Inbred Strains
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
Administration, Cutaneous
The application of suitable drug dosage forms to the skin for either local or systemic effects.
Tissue Distribution
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Dogs
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Double-Blind Method
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Cross-Over Studies
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Treatment Outcome
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Blood Pressure
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Administration, Sublingual
Administration of a soluble dosage form by placement under the tongue.
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Administration, Inhalation
The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.
Kidney
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
Infusions, Parenteral
The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Random Allocation
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
Behavior, Animal
The observable response an animal makes to any situation.
Drug Tolerance
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.
Morphine
The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
Recombinant Proteins
Proteins prepared by recombinant DNA technology.
Plant Extracts
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
Injections
Introduction of substances into the body using a needle and syringe.
Analysis of Variance
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Injections, Spinal
Introduction of therapeutic agents into the spinal region using a needle and syringe.
Organ Size
The measurement of an organ in volume, mass, or heaviness.
Metabolic Clearance Rate
Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
Chromatography, High Pressure Liquid
Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Rabbits
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
Mice, Inbred ICR
Lung
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Rats, Inbred F344
Analgesics, Opioid
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
Self Administration
Administration of a drug or chemical by the individual under the direction of a physician. It includes administration clinically or experimentally, by human or animal.
Ethanol
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.
Heart Rate
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Estradiol
The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
Motor Activity
The physical activity of a human or an animal as a behavioral phenomenon.
Antineoplastic Agents
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Drug Combinations
Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.
Mice, Knockout
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.
Hemodynamics
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Mice, Inbred Strains
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.
Drug Evaluation, Preclinical
Preclinical testing of drugs in experimental animals or in vitro for their biological and toxic effects and potential clinical applications.
Analgesics
Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
Drug Therapy, Combination
Therapy with two or more separate preparations given for a combined effect.
Enzyme Inhibitors
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Injections, Intra-Arterial
Delivery of drugs into an artery.
Administration, Buccal
Administration of a soluble dosage form between the cheek and gingiva. It may involve direct application of a drug onto the buccal mucosa, as by painting or spraying.
Spleen
An encapsulated lymphatic organ through which venous blood filters.
Piperidines
A family of hexahydropyridines.
Prodrugs
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Antibodies, Monoclonal
Antibodies produced by a single clone of cells.
Intestinal Absorption
Uptake of substances through the lining of the INTESTINES.
Blood Glucose
Glucose in blood.
Drug Approval
Process that is gone through in order for a drug to receive approval by a government regulatory agency. This includes any required pre-clinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance of the drug.
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Drug Synergism
The action of a drug in promoting or enhancing the effectiveness of another drug.
Cocaine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Naloxone
A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
Eating
The consumption of edible substances.
United States
Dopamine
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
Genetic Therapy
Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.
Nitric Oxide
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Cytokines
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Hydrocortisone
The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.
Absorption
The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
Cells, Cultured
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Lipopolysaccharides
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Immunohistochemistry
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Delayed-Action Preparations
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
Insulin
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Pain Measurement
Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Biotransformation
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
Testosterone
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Anti-Inflammatory Agents
Substances that reduce or suppress INFLAMMATION.
Anti-Bacterial Agents
Substances that reduce the growth or reproduction of BACTERIA.
Microdialysis
A technique for measuring extracellular concentrations of substances in tissues, usually in vivo, by means of a small probe equipped with a semipermeable membrane. Substances may also be introduced into the extracellular space through the membrane.
Dexamethasone
An anti-inflammatory 9-fluoro-glucocorticoid.
Progesterone
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
Genetic Vectors
DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.
Growth Hormone
A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
Administration, Intravaginal
The insertion of drugs into the vagina to treat local infections, neoplasms, or to induce labor. The dosage forms may include medicated pessaries, irrigation fluids, and suppositories.
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
Tumor Necrosis Factor-alpha
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
Animals, Newborn
Refers to animals in the period of time just after birth.
Antioxidants
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
Body Temperature
The measure of the level of heat of a human or animal.
Models, Animal
Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.
Drug Delivery Systems
Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.
Narcotic Antagonists
Agents inhibiting the effect of narcotics on the central nervous system.
Kinetics
The rate dynamics in chemical or physical systems.
Bile
An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum.
United States Department of Veterans Affairs
A cabinet department in the Executive Branch of the United States Government concerned with overall planning, promoting, and administering programs pertaining to VETERANS. It was established March 15, 1989 as a Cabinet-level position.
Gonadotropin-Releasing Hormone
A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Phytotherapy
Use of plants or herbs to treat diseases or to alleviate pain.
Drugs, Chinese Herbal
Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.
Vasodilator Agents
Drugs used to cause dilation of the blood vessels.
Pyridines
Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
Luteinizing Hormone
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.
Diabetes Mellitus, Experimental
Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
Piperazines
Neoplasms, Experimental
Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.
Prospective Studies
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Mice, Nude
Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.
Device Approval
Process that is gone through in order for a device to receive approval by a government regulatory agency. This includes any required preclinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance. It is not restricted to FDA.
Mice, Transgenic
Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
Neoplasm Transplantation
Experimental transplantation of neoplasms in laboratory animals for research purposes.
Apoptosis
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Infusion Pumps
Fluid propulsion systems driven mechanically, electrically, or osmotically that are used to inject (or infuse) over time agents into a patient or experimental animal; used routinely in hospitals to maintain a patent intravenous line, to administer antineoplastic agents and other drugs in thromboembolism, heart disease, diabetes mellitus (INSULIN INFUSION SYSTEMS is also available), and other disorders.
Pyrazoles
Azoles of two nitrogens at the 1,2 positions, next to each other, in contrast with IMIDAZOLES in which they are at the 1,3 positions.
Glucocorticoids
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Regional Blood Flow
The flow of BLOOD through or around an organ or region of the body.
Methamphetamine
A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.
Serotonin
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Adjuvants, Immunologic
Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Diazepam
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
Corticosterone
An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Anesthesia
A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
Chemistry, Pharmaceutical
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
Adrenocorticotropic Hormone
An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).
Drug Carriers
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Central Nervous System Stimulants
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
Ovariectomy
The surgical removal of one or both ovaries.
Hyperalgesia
An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.
Neuroprotective Agents
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Mice, Inbred C3H
Leukocyte Count
The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.
Hypnotics and Sedatives
Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
Gene Expression
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
Analgesics, Non-Narcotic
A subclass of analgesic agents that typically do not bind to OPIOID RECEPTORS and are not addictive. Many non-narcotic analgesics are offered as NONPRESCRIPTION DRUGS.
Intestines
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
Haloperidol
A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
Drug-Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, and chemicals from the environment.
Imidazoles
Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).
Anti-Anxiety Agents
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
Indomethacin
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
Brain Chemistry
Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.
Placebos
Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.
Suppositories
Medicated dosage forms that are designed to be inserted into the rectal, vaginal, or urethral orifice of the body for absorption. Generally, the active ingredients are packaged in dosage forms containing fatty bases such as cocoa butter, hydrogenated oil, or glycerogelatin that are solid at room temperature but melt or dissolve at body temperature.
Hypothalamus
Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE.
Gene Expression Regulation
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Substance Withdrawal Syndrome
Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
Adenoviridae
A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS) or both (ATADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases.
Iodine Radioisotopes
Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes.
Edema
Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Neurons
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
Nitric Oxide Synthase
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
Infusion Pumps, Implantable
Implanted fluid propulsion systems with self-contained power source for providing long-term controlled-rate delivery of drugs such as chemotherapeutic agents or analgesics. Delivery rate may be externally controlled or osmotically or peristatically controlled with the aid of transcutaneous monitoring.
Chorionic Gonadotropin
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
Feces
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
Blotting, Western
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Narcotics
Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS.
Oxidative Stress
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
Clinical Trials as Topic
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Erythropoietin
Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.
Acute Disease
Disease having a short and relatively severe course.
Hypoglycemic Agents
Substances which lower blood glucose levels.
Rats, Inbred Lew
Endotoxins
Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.
Sheep
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
Immunoglobulin G
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
Myocardium
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Nicotine
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Sulfonamides
A group of compounds that contain the structure SO2NH2.
Amphetamine
A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
Injections, Intradermal
The forcing into the skin of liquid medication, nutrient, or other fluid through a hollow needle, piercing the top skin layer.
Corpus Striatum
Striped GRAY MATTER and WHITE MATTER consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the THALAMUS in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The WHITE MATTER is the INTERNAL CAPSULE.
Intestinal Mucosa
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Indoles
Benzopyrroles with the nitrogen at the number one carbon adjacent to the benzyl portion, in contrast to ISOINDOLES which have the nitrogen away from the six-membered ring.

Homing of stem cells to sites of inflammatory brain injury after intracerebral and intravenous administration: a longitudinal imaging study. (1/222)

 (+info)

Intravenous therapies for castration-resistant prostate cancer: toxicities and adverse events. (2/222)

 (+info)

Population pharmacokinetic and pharmacodynamic model-based comparability assessment of a recombinant human Epoetin Alfa and the Biosimilar HX575. (3/222)

 (+info)

Variability in the use of intravenous thrombolysis for mild stroke: experience across the SPOTRIAS network. (4/222)

 (+info)

Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate and azathioprine. (5/222)

 (+info)

A novel vitamin K1 2,3-epoxide reductase (VKOR) inhibitor, 3-acetyl-5-methyltetronic acid, reduces experimental glomerulonephritis. (6/222)

Excessive proliferation of mesangial cells is observed in various types of glomerular disease including glomerulonephritis (GN), which is progressive in nature and eventually results in end-stage renal disease (ESRD). Vitamin K(1) 2,3-epoxide reductase (VKOR) and the vitamin K-dependent growth arrest-specific gene 6/Axl pathway play a key role in mesangial cell proliferation in GN. In the present study, we indicate the potential of a VKOR inhibitor, 3-acetyl-5-methyltetronic acid (AMT), to prevent the proliferation of glomerular mesangial cells and suppress the progression of GN. AMT was administered intravenously to rats once daily for 12 days and a mouse anti-Thy1 monoclonal antibody was injected intravenously after the AMT treatment on Day 6. Creatinine clearance (CCr) significantly increased and the albumin-to-creatinine ratio (ACR) significantly decreased in the AMT-treated group of the Thy-1 GN rats. In addition, glomerular and tubular damage was improved histopathologically in the AMT-treated group. AMT did not affect blood coagulation due to its unique pharmacokinetic properties. The concentration of AMT reached the IC(50) for VKOR in kidney, but not in liver. A novel VKOR inhibitor, AMT, reduced renal mesangial cell proliferation and could be a supportive treatment for GN.  (+info)

Population pharmacokinetic model of canrenone after intravenous administration of potassium canrenoate to paediatric patients. (7/222)

 (+info)

Paricalcitol versus cinacalcet plus low-dose vitamin D therapy for the treatment of secondary hyperparathyroidism in patients receiving haemodialysis: results of the IMPACT SHPT study. (8/222)

 (+info)

Sharon of Israel Has a Mild Stroke - Summary - NYTimes.comSharon of Israel Has a Mild Stroke - Summary - NYTimes.com
Prime Minister Ariel Sharon of Israel suffered a mild stroke and was hospitalized, but within hours he was recovering and in good condition, spokesmen for the hospital and Mr. Sharons office said. |p| The episode raised questions about whether Mr. Sharon, 77, would be able to continue in his post and whether he would be able to seek a third term as prime minister. |p| Article, Page A18. |p|
http://query.nytimes.com/gst/fullpage.html?res=9F0CE1DC1730F93AA25751C1A9639C8B63
A Phase IIIB, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Alteplase in Patients With Mild Stroke:...A Phase IIIB, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Alteplase in Patients With Mild Stroke:...
PRISMS is a double-blind, multicenter, randomized, Phase IIIb study to evaluate the efficacy and safety of intravenous (IV) alteplase in participants with mild
http://adisinsight.springer.com/trials/700241646?error=cookies_not_supported&code=c6ca599f-8bd8-436a-92be-b8ad3eeb06f7
Central Nervous System T-wavesCentral Nervous System T-waves
I believe the latter is more likely, as T-waves like this are most commonly seen in CNS catastrophes. A mild stroke is normally not enough to cause this (it is not enough of a CNS catastrophe), but I think this goes to show how intimate the connection between the brain and the heart can be ...
http://hqmeded-ecg.blogspot.com/2015/09/central-nervous-system-t-waves.html
DWI-ASPECTS as a Predictor of Dramatic Recovery After Intravenous Recombinant Tissue Plasminogen Activator Administration in...DWI-ASPECTS as a Predictor of Dramatic Recovery After Intravenous Recombinant Tissue Plasminogen Activator Administration in...
DWI-ASPECTS ≥7 was an independent predictor of short-term neurological recovery after an M1-MCAO. Limited DWI changes before IV-tPA have been reported as a predictor of neurological recovery.4 Presence of a clinical-DWI mismatch defined as DWI-ASPECTS ≥7 and an NIHSS score ≥8 has also been reported to be predictors of neurological recovery after IV-tPA.5 An advantage of our study is that the utility of DWI-ASPECTS was evaluated after adjusting for several established imaging and laboratory parameters.. Although early recanalization was associated with DR in patients with DWI-ASPECTS ≥7 and ,7, its role regarding clinical and radiological outcomes depended on the initial DWI-ASPECTS. In patients with DWI-ASPECTS ≥7, the favorable outcome rate and follow-up infarct volume were not statistically different between patients with and without early recanalization. To the contrary, in patients with DWI-ASPECTS ,7, favorable outcomes were only seen in patients with early recanalization. Early ...
http://stroke.ahajournals.org/content/44/2/534.long
A Study of Bitopertin (RO4917838) in Combination With Selective Serotonin Reuptake Inhibitors (SSRIs) in Participants With...A Study of Bitopertin (RO4917838) in Combination With Selective Serotonin Reuptake Inhibitors (SSRIs) in Participants With...
This multicenter, randomized, double-blind, parallel-group, placebo-controlled study will evaluate the efficacy and safety of bitopertin in combination with SSRI in participants with obsessive-compulsive disorder. Participants will be randomized to receive either bitopertin 30 milligrams (mg) or bitopertin 10 mg or placebo orally daily in addition to their background therapy with an SSRI. Participants will be allocated to one of two strata. Participants in Stratum 1 will start study drug on Day 1. Participants in Stratum 2 will receive placebo from Day 1 (placebo lead-in) and will then start study drug at the Week 2 visit. Participants in both strata will receive the study drug in addition to their background therapy with an SSRI until Week 16 ...
https://clinicaltrials.gov/ct2/show/study/NCT01674361
Harold Camping Suffers Mild Stroke; Released From HospitalHarold Camping Suffers Mild Stroke; Released From Hospital
Family Radio Network preacher Harold Camping, known for his failed rapture prediction, will be released from an Oakland, Calif.-area hospital where he was treated for a mild stroke, Family Radio employees said Monday.
https://www.christianpost.com/news/harold-camping-suffers-mild-stroke-released-from-hospital-51127/
Intravenous Delivery of Clot-busting Drug Still Best Intervention for Ischemic Stroke ( Intravenous delivery of an approved clo...Intravenous Delivery of Clot-busting Drug Still Best Intervention for Ischemic Stroke ( Intravenous delivery of an approved clo...
Health,Intravenous delivery of an approved clot-busting drug remains the most... The Guidelines for the Early Management of Adults with Ischemic S... The guidelines focus on the crucial first hours from the time an ... The panel emphasized the importance of public education on the sy... ? Sudden numbness or weakness of the face arm or leg especially...,Intravenous,Delivery,of,Clot-busting,Drug,Still,Best,Intervention,for,Ischemic,Stroke,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
http://www.bio-medicine.org/medicine-news/Intravenous-Delivery-of-Clot-busting-Drug-Still-Best-Intervention-for-Ischemic-Stroke-19881-1/
CBN TV - Charlie Daniels Recovering from Mild StrokeCBN TV - Charlie Daniels Recovering from Mild Stroke
iframe width=640 height=360 src=http://cbn.com/tv/embedplayer.aspx?bcid=1384141689001 frameborder=0 allowfullscreen,,/iframe ...
http://www.cbn.com/tv/1384141689001
medical flow regulator iv administration sets price
The B Braun Rate Flow Regulator IV Set carefully regulates the flow of medication or fluids to the patient through an IV.There are two IV administration set options with varying drip rates The B Braun V5922 IV Administration Set with Rate Flow Regulator has a drip rate of 20 drops/mL and the B Braun V5926 Mini Drop IV Administration Set with Rate Flow regulator has 60 drops/mL. ...
http://www.ebenisterie-menuiserie-fraysse.fr/Mar/21-11250.html
AirStop And PrimeStop IV Administration Set - - Products - Netgagerdesign.comAirStop And PrimeStop IV Administration Set - - Products - Netgagerdesign.com
BQ Plus Medical Co.,Ltd is one of the top level China airstop and primestop iv administration set manufacturers, welcome to wholesale airstop and primestop iv administration set from our factory. 1.Product Description: AirStopPrimeStop IV Set is kind of n
http://www.netgagerdesign.com/products/show-htm-itemid-35672.html
Strokes can occur in younger people too - LA TimesStrokes can occur in younger people too - LA Times
A mild stroke in middle age, such as the one suffered by Beau Biden, isn't uncommon, doctors say. And the cause could be a number of things.
http://www.latimes.com/la-he-stroke-20100517-story.html
The Stroke Saga | A Labor of LikeThe Stroke Saga | A Labor of Like
The story so far (5/29/2011) All, I had a little mishap this week. Now that the immediate crisis has passed, I wanted to get my version of events out so that the rumors and cheap, sleazy innuendo can all start from the same basis. Thursday morning I had what doctors are calling a mild stroke.…
https://laboroflike.wordpress.com/the-stroke-saga/
Peginesatide (Omontys) | Daviss Drug GuidePeginesatide (Omontys) | Daviss Drug Guide
Find information on Peginesatide (Omontys) in Daviss Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.
https://nursing.unboundmedicine.com/nursingcentral/view/Davis-Drug-Guide/109652/all/peginesatide?refer=true
Paracervical block financial definition of paracervical blockParacervical block financial definition of paracervical block
Definition of paracervical block in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is paracervical block? Meaning of paracervical block as a finance term. What does paracervical block mean in finance?
http://financial-dictionary.thefreedictionary.com/paracervical+block
A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients...A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients...
As discussed above, no satisfying therapeutic options exist for treatment of locally advanced and metastatic pancreatic cancer. The prognosis is dismal with a six-month progression-free survival of approximately 50% and a median survival of about 11 months [5].. The first open, non-randomized clinical trial with ParvOryx, referred to as ParvOryx01, evaluated safety and tolerability as well as antitumor activity and clinical efficacy in patients with progressive primary or recurrent glioblastoma multiforme (GBM). ParvOryx01 was completed in May 2015 [18]. The investigated doses ranged between 1E06 and 5E09 pfu. They were administered as combination of either multiple intravenous infusions or a single intratumoral injection and multifocal intracerebral injections at the end of tumor resection surgery. As in the current trial, the intravenous dose was divided into equal fractions which were given on consecutive days. The interval between the first administration and surgery with subsequent ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-017-3604-y
A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients...A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients...
As discussed above, no satisfying therapeutic options exist for treatment of locally advanced and metastatic pancreatic cancer. The prognosis is dismal with a six-month progression-free survival of approximately 50% and a median survival of about 11 months [5].. The first open, non-randomized clinical trial with ParvOryx, referred to as ParvOryx01, evaluated safety and tolerability as well as antitumor activity and clinical efficacy in patients with progressive primary or recurrent glioblastoma multiforme (GBM). ParvOryx01 was completed in May 2015 [18]. The investigated doses ranged between 1E06 and 5E09 pfu. They were administered as combination of either multiple intravenous infusions or a single intratumoral injection and multifocal intracerebral injections at the end of tumor resection surgery. As in the current trial, the intravenous dose was divided into equal fractions which were given on consecutive days. The interval between the first administration and surgery with subsequent ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-017-3604-y/
Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke - Full Text View -...Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke - Full Text View -...
Every year, thousands of people in Canada either die or are permanently disabled after suffering a stroke. This costs our society billions of dollars in physician services, hospital expenses, and decreased productivity. Some individuals are slightly more lucky; instead of having a severe stroke, they have either a very mild stroke or temporary stroke symptoms, also known as a transient ischemic attack (TIA), and do not experience any loss of abilities. However, mild strokes and TIAs can precede the onset of a more serious, disabling stroke. Most of the significant strokes that happen after a mild stroke or TIA occur within days of the original event; there is a need for early interventions that could prevent such occurrences.. One of the goals of recent research has been to find ways to prevent major strokes after individuals have sustained a minor stroke or TIA. Up until now, stroke doctors have focused on treating elevated blood pressures and cholesterol levels, scanning the blood vessels in ...
https://clinicaltrials.gov/ct2/show/NCT01528462?recr=Open&cond=%22Restless+Legs+Syndrome%22&rank=14
Disappointing outcome of bitopertin treatment for negative symptoms in schizophrenia
The consequences of the trials were promulgated in a scrap in Biological Psychiatry by Dr. Dragana Bugarski-Kirola of Roche Pharmaceuticals in Basal, Switzerland. The randomized, double-blind, parallel-group, placebo-controlled libraries were a collaboration between Roche and detached research installations about the the human scramble.. We are backside to the sketch embark on, undignified Dr. John Krystal, Redactor of Biological Psychiatry.. Above-mentioned undertakings to analyse pessimistic earmarks compel ought to hired dopes, hormones, and brains stimulation, but no one bring into the world contributed the desired clinical edge. Research engineer glutamate signaling in denying symptoms has itchy the idea of end glutamate receptors, but this method has peter out in muscular pests. Glycine reuptake inhibitors upkeep been cogitate oned a encouraging alterative to augment glutamatergic signaling, and a humiliated proof-of-concept test showed that bitopertin, which selectively put an ends ...
http://hiez.net/health-and-medicine/disappointing-outcome-of-bitopertin-treatment-for-negative-symptoms-in-schizophrenia.html
Cyclophosphamide facilitates antitumor efficacy against subcutaneous tumors following intravenous delivery of reovirus -...Cyclophosphamide facilitates antitumor efficacy against subcutaneous tumors following intravenous delivery of reovirus -...
Qiao, J, Wang, H, Kottke, T, White, C, Twigger, K, Diaz, RM, Thompson, J, Selby, P, de Bono, J, Melcher, A et al, Pandha, H, Coffey, M, Vile, R and Harrington, K. (2008) Cyclophosphamide facilitates antitumor efficacy against subcutaneous tumors following intravenous delivery of reovirus ...
http://epubs.surrey.ac.uk/823998/
Jennerex Announces First Patient Treated in Phase 2 Clinical Trial of Intravenous Delivery JX-594Jennerex Announces First Patient Treated in Phase 2 Clinical Trial of Intravenous Delivery JX-594
SAN FRANCISCO, July 25, 2012- Jennerex Announces First Patient Treated in Phase 2 Clinical Trial of Intravenous Delivery JX-594 In Patients with Advanced Liver Cancer.
http://www.newswire.ca/fr/news-releases/jennerex-announces-first-patient-treated-in-phase-2-clinical-trial-of-intravenous-delivery-jx-594-in-patients-with-advanced-liver-cancer-510507971.html
What is paracervical block? - Answered by top doctors on HealthTapWhat is paracervical block? - Answered by top doctors on HealthTap
Dr. Edsall responded: Numbing the nerves. The doctor puts his fingers in the vagina and guides the needle beside the |a href=/topics/cervix track_data={
https://www.healthtap.com/user_questions/71897-what-is-paracervical-block
Drug no better than aspirin for stroke prevention - Harvard HealthDrug no better than aspirin for stroke prevention - Harvard Health
A study found that the drug ticagrelor (Brilinta) was no better than aspirin at preventing stroke among people who had a mild stroke or a transient ischemic…
https://www.health.harvard.edu/stroke/drug-no-better-than-aspirin-for-stroke-prevention
My life through the lens...: December 2011
Id like to nominate my family for your deserving family photo session. On Nov 13th Of this year (yes, just over a month ago) I brought my Mom to the hospital because I suspected she was having a mild stroke. At exactly 4pm that day, they told us she had a massive brain tumor...and our lives changed forever. My Mom, just 63, has always been vibrant, active, independent, and the life of the party. Since her diagnosis and subsequent craniotomy two days later, she has become flat, dependant and Someone so unlike the Mom I know. She has been living in my home since being released from the hospital. We go to Hartford everyday for radiation treatments and she takes chemo pills every night. But the tumor progresses and her memory and abilities have become limited -- even in such a very short time. After being told she had a prognosis of 12 months when she was first diagnosed, the oncologists now tell me she is more likely to pass within 3 to 6 months. This all happened so suddenly. ...
http://tabphotographicishere.blogspot.com/2011/12/
My life through the lens...: 2011
Id like to nominate my family for your deserving family photo session. On Nov 13th Of this year (yes, just over a month ago) I brought my Mom to the hospital because I suspected she was having a mild stroke. At exactly 4pm that day, they told us she had a massive brain tumor...and our lives changed forever. My Mom, just 63, has always been vibrant, active, independent, and the life of the party. Since her diagnosis and subsequent craniotomy two days later, she has become flat, dependant and Someone so unlike the Mom I know. She has been living in my home since being released from the hospital. We go to Hartford everyday for radiation treatments and she takes chemo pills every night. But the tumor progresses and her memory and abilities have become limited -- even in such a very short time. After being told she had a prognosis of 12 months when she was first diagnosed, the oncologists now tell me she is more likely to pass within 3 to 6 months. This all happened so suddenly. ...
http://tabphotographicishere.blogspot.com/2011/
Cyto-Set. Safer cytostatic preparation and application. IV Administration - PDFCyto-Set. Safer cytostatic preparation and application. IV Administration - PDF
Cyto-Set Safer cytostatic preparation and application IV Administration Always a closed system Protect yourself and your environment The number of cytostatic infusions that have to be prepared is growing
http://docplayer.net/224427-Cyto-set-safer-cytostatic-preparation-and-application-iv-administration.html
Metoprolol Iv Administration
Metoprolol Iv Administration. 100% Secure and Anonymous, Best Quality Discount Prescription Drugs, Available free Delivery to USA & WorldWide!
https://canadianrxusa.com/metoprolol-iv-administration-2196-bb
Buy Romsons RMS Vented IV Administration Set at best price online in India|SMBBuy Romsons RMS Vented IV Administration Set at best price online in India|SMB
Buy Romsons RMS Vented IV Administration Set online at best prices. 20 drops/ml Drop rate, 150 cm Kink Resistant Tube, Collapsible Drip Chamber. COD Available.
https://www.smartmedicalbuyer.com/Brand/rms-iv-set
Lasix iv administration
The expected shelf life of Brackett elements stored in their original packaging and out of direct sunlight is as follows: 4 years from date of manufacture
https://www.onlinecasinogame.us.org/Canadian+Prescription/lasix-iv-administration-2100
Myers CocktailMyers Cocktail
Intravenous administration of nutrients can achieve serum concentrations not obtainable with oral, or even intramuscular (IM), administration.
http://orthomolecularnutrition.net/vitamin-therapy/customized-iv-nutrient-therapy/myers-cocktail
Intrathecal Labor Analgesia, Paracervical Block, Transcutaneous Electrical erve Stimulation (TENS) cara menghilangkan Rasa...Intrathecal Labor Analgesia, Paracervical Block, Transcutaneous Electrical erve Stimulation (TENS) cara menghilangkan Rasa...
Intrathecal Labor Analgesia, Paracervical Block, Transcutaneous Electrical erve Stimulation (TENS), lok saraf perineal dan pudendal merupakan metode atau cara menghilangkan Rasa Sakit Persalinan secara Medis. Berikut penjelasannya: Intrathecal Labor Analgesia (ILA). Teknik ILA dilakukan dengan cara menyuntikkan obat penghilang rasa sakit kepada ibu yang akan bersalin normal. Obat ini disuntikkan di daerah urat saraf, yaitu pada tulang belakang bagian bawah. Teknik ILA membebaskan ibu dari rasa nyeri persalinan sekitar 12 jam. Paracervical Block. Paracervical block juga tergolong pembiusan. Metode ini digunakan untuk menghilangkan rasa sakit pada persalinan tahap pertama. Anestesi diberikan melalui suntikan di sisi leher rahim sehingga menghambat rasa sakit. Paracervical block berisiko menghambat detak jantung bayi sehingga dikhawatirkan membahayakan bayi.. Blok saraf perineal dan pudendal. Blok saraf pudendal merupakan suntikan untuk mengebalkan saraf yang mengirim informasi sakit ke area ...
http://masmintos.blogspot.com/2011/03/intrathecal-labor-analgesia.html
Manuka Honey Herpes
Manuka honey genital herpes is a kind of disease relieve of herpes. of this honey twice a day when I was first healing my stomach lining. Manuka honey is the best quality of honey available. Manuka Honey & Herpes What is Manuka Honey? Honey in itself has been a long-time, natural medicine for healing many wounds caused by bacteria and inflammation. Whether it truly works or not is unknown, though researchers out of Germany have found that Manuka essential oil…. Activon Tube contains 100% Manuka honey with no additives from New Zealand. Really tempted to buy beck pulser & lauricidin, rife machine is too expensive. Manuka Honey Acne How To Vitamin For Acid Gel Scars Page 4 of 5. Another antibacterial component in Manuka honey is methylglyoxal (MG). What is UMF 16+, MGO 400+, Active? Deciphering manuka honey: UMF15+, MGO400, 24+ Bio Active, KFactor16, TA. It was even discovered in the tomb of King Tut. See more ideas about Health remedies, Natural cures, Health. Clinical trials have found that ...
http://fwtt.fnaarccuneo.it/manuka-honey-herpes.html
Manuka Honey Eye Drops
This is a special type of honey extracted only from New Zealand. Manuka honey, a highly medicinal honey found only in the tiny nation, has captured the attention of doctors, researchers and health freaks everywhere. Some people are now even starting to make home-made mixtures with raw honey. You will chose right product because my site use AI Technology and Big Data to filter milions products. Most eye patients treated in the. Manuka Oil is believed to be beneficial for foot and body odor. Made with our high grade MGO400+ Manuka Honey, certified for natural methylglyoxal content (400mg/kg). For medical purposes raw honey should be used. We are acquainted with many foods where honey is an. Manuka honey proved to be more efficient than single antibiotics against biofilms of Pseudomonas aeruginosa and Staphylococcus aureus. The best type of honey for treating eye infections is Manuka honey. As Manuka honey has various benefits, how to make Manuka honey eye drops gain popularity as it is claimed to ...
http://fiorionline-milano.it/lkiv/manuka-honey-eye-drops.html
Manuka Honey Bio Active 10+, 500 gramManuka Honey Bio Active 10+, 500 gram
Description. Comvita Bio Active 10+ Manuka Honey contains a high level of antibacterial activity not found in other honeys. For digestive health and to assist the digestive process. Every batch of Comvita Bio Active 10+ Manuka Honey is tested by an independent laboratory for UMF antibacterial activity, using a testing methods developed at Waikato University. Each jar is guaranteed to have an antibacterial activity 2,5 times greater than standard antiseptic (minimum 10% cabolic equivalent). Comvita Bio Active 10+ Manuka Honey is packaged in an un-breakable, brown-tinted container, designed to protect important natural components present in the honey from destruction by light. Comvita Bio Active 10+ Manuka Honey, is pure, raw, natural honey with all the natural enzymes and pollen intact. Comvita Bio Active 10+ Manuka Honey has a very long shelf life with excellent preservation of its health-giving qualities. One Doctor likes to tell the story of the 20-year-old wound. Infected with ...
http://www.herbalremedies.com/manuka-honey.html
Is a constant headache & swollen feet an after effect of a mild stroke or a side effect of warfarin?Is a constant headache & swollen feet an after effect of a mild stroke or a side effect of warfarin?
2 Answers (question resolved) - Posted in: headache, ischemic stroke, warfarin - Answer: Hi, headache and unexplained swelling are both possible side ...
https://www.drugs.com/answers/ischemic-stroke-are-a-persistent-headache-and-425183.html
Three Peaks Manuka Honey UMF 20+ (MGO 829) Tongariro Jar - Love From New ZealandThree Peaks Manuka Honey UMF 20+ (MGO 829) Tongariro Jar - Love From New Zealand
There is Manuka honey, and then there is Three Peaks Manuka Honey. Sourced in the pristine Tongariro National Park and UMF verified, Three Peaks create high-quality manuka honey which contains over 200 compounds not seen in any other honey. What is UMF? Honey producers have a scale for rating the potency of manuka hone
https://lovefromnewzealand.com/products/three-peaks
What is manuka honey?What is manuka honey?
Manuka honey for wounds of all kinds is used as a natural ointment. In an age of resistance to conventional antibiotics, it has been hailed as a go-to germ fighter. Proponents also claim that Manuka honey can treat problems from acne to sinus problems with other conditions. Manuka honey has not been used as a tradition
https://www.eiwahoney.com/blogs/honey-and-health/what-is-manuka-honey
Manuka Honey & Propolis Soap - KiwiCorpManuka Honey & Propolis Soap - KiwiCorp
Southern Isles® Manuka Honey & Propolis Soap contains Manuka Honey, propolis extract and Vitamin E, both Manuka Honey and Propolis have natural antiseptic and antibacterial properties, creating an optimum healing environment and a protective barrier that will cleanse and nourish your skin, rejuvenating and keeping
https://kiwicorp.co.nz/collections/soap/products/manuka-honey-propolis-soap
Buy Comvita UMF 15+ Manuka Honey 250g (Not Available in WA) Online at Chemist Warehouse®Buy Comvita UMF 15+ Manuka Honey 250g (Not Available in WA) Online at Chemist Warehouse®
Manuka Honey from Comvita is authentic New Zealand sourced UMF(TM)-graded Manuka Honey. which independentyl verified using the UMF(TM) trade mark, for its unique properties. UMF™ trade mark is an assurance that you are buying premium quality, unadulterated Manuka Honey, with unique properties remaining true to the source from hive to shelf.
https://www.chemistwarehouse.com.au/buy/64186/comvita-umf-15-manuka-honey-250g-not-available-in-wa?rcid=924
Active Manuka Honey UMF®16+ 3 Month SupplyActive Manuka Honey UMF®16+ 3 Month Supply
Buy online and learn more about Active Manuka Honey UMF®16+ 3 Month Supply from Manuka Honey USA, the original Manuka honey company in the United States.
https://manukahoneyusa.com/product/active-manuka-honey-umf16-3-month-supply-6x17-5oz-jars/
What Is Manuka Honey? - 6 Manuka Honey Benefits & UsesWhat Is Manuka Honey? - 6 Manuka Honey Benefits & Uses
Manuka honey from New Zealand has potent antibacterial properties that can help treat cuts, improve skin, and bolster gut health. Here, the manuka benefits you should know, how to use it, and where to buy it.
https://www.prevention.com/food-nutrition/a23691441/manuka-honey-benefits/
Manuka Honey Could Halt Growth of Cancer CellsManuka Honey Could Halt Growth of Cancer Cells
For many years Manuka Honey has been known for its antibacterial properties, but its properties have never been studied for cancer research. Until now, UAE University conducted an over five year study where they researched the effects of cancer cells when they were tested with Manuka Honey. A UAE University official said, Though the honey,…
https://blog.shoppri.com/2015/08/11/manuka-honey-could-halt-growth-of-cancer-cells/
Stores that Carry Active Manuka Honey - Health Benefits - InfoBarrel
Introduction In this article I will be telling you about the Stores that carry active Manuka honey. As you know that buying Manuka honey is extremely hard as it is very difficult to find a place to purchase the honey from also sometimes people get mistaken by how...
http://www.infobarrel.com/Stores_that_Carry_Active_Manuka_Honey_-_Health_Benefits
Advancis Medical Activon - Activon - 100% Medical Grade Manuka Honey 25g Tube - G Baldwin & CoAdvancis Medical Activon - Activon - 100% Medical Grade Manuka Honey 25g Tube - G Baldwin & Co
|p|100% Medical Grade Manuka honey|/p| |p|Features|/p| |p|Manuka honey brings the following properties:|/p| |p|Anti-bacterial, effectively kills harmful bacteria|/p| |p|Anti-inflammatory|/p| |p|Eliminates odours without masking them|/p| |p|Osmotic effect,
https://www.baldwins.co.uk/advancis-medical-activon-activon-100-medical-grade-manuka-honey-25g-tube
MANUKA HONEY PREMIUM PLUS RANGE - 10+ | FeltMANUKA HONEY PREMIUM PLUS RANGE - 10+ | Felt
We have extended our range of quality Manuka Honey to include this Premium+ Range of 250g Jars of Manuka Honey, available in 10+, 15+ and the highly sought after ...
https://felt.co.nz/listing/429596/MANUKA-HONEY-PREMIUM-PLUS-RANGE---10
Buy Manuka Honey Online in India at Rs.2744 | HealthyworldBuy Manuka Honey Online in India at Rs.2744 | Healthyworld
Wild Cape Manuka Honey 250g, High UMF factor. Its antiviral, antiseptic, antifungal, and antibacterial action is useful for making medicines. Visit our Healthyworld online store & browse through Manuka Honey Free Shipping, CoD. Order Now!
https://www.healthyworld.in/wild-cape-manuka-honey-250g
Neurologist explains what symptoms are accumulating and explains - Archynetys
There have been several examinations in the USA and we are also observing it with concern in European countries such as Italy, Spain and Germany: Significantly fewer patients with minor strokes come to the clinics and are there on stroke units - departments specializing in stroke patients in the hospital - treat. We fear that this will have an indirect impact of the pandemic because people are afraid of getting infected in the hospital and therefore do not take stroke warning symptoms as seriously as they should. Every second stroke there are volatile symptoms, also known as transient ischemic attack (TIA) or mild stroke. And these precede severe strokes. At the moment we cannot really assess the impact of the pandemic, but we fear that severe strokes will end up being more common than before. And not just because of the virus, but mainly because those affected do not go to the clinic if there are warning signs.. The Transient ischemic attack - in short TIA - is considered a harbinger of a ...
https://www.archynetys.com/neurologist-explains-what-symptoms-are-accumulating-and-explains/
Catherine Deneuve Is Feeling Fine but Still Recuperating From Stroke - VarietyCatherine Deneuve Is Feeling Fine but Still Recuperating From Stroke - Variety
French screen icon Catherine Deneuve is feeling fine but still recuperating in a Paris hospital from a mild stroke, her publicist said.
https://variety.com/2019/film/news/catherine-deneuve-still-recuperating-mild-stroke-1203409139/
Pregnancy and Stroke - Neurology - MedHelpPregnancy and Stroke - Neurology - MedHelp
I am a 38 year old female who suffered a mild stroke 3 weeks ago. I was approx 12 weeks pregnant at the time. I have not used birth control pills for almost 10 years. The doctors say it was a blod clo...
https://www.medhelp.org/posts/Neurology/Pregnancy-and-Stroke/show/294049
What is Transient Ischemic Attack: Symptoms, Causes, Diagnosis, and Treatment | Empowering Lives | DocDocWhat is Transient Ischemic Attack: Symptoms, Causes, Diagnosis, and Treatment | Empowering Lives | DocDoc
Transient ischemic attack (TIA) is a mild stroke caused by a brief interruption of blood flow to the brain. It causes stroke-like symptoms, such as...
https://www.docdoc.com/info/condition/stroke-transient-ischemic-attack/
Manuka Honey Benefits, Uses, Dosage & Side EffectsManuka Honey Benefits, Uses, Dosage & Side Effects
Learn about the potential health benefits and uses of Manuka Honey including dosage, side effects, drug interactions and safety profile.
https://www.ayurtimes.com/manuka-honey-benefits-uses/
Arataki Honey Manuka Honey UMF 5+ | HealthPost NZArataki Honey Manuka Honey UMF 5+ | HealthPost NZ
Arataki Honey Manuka Honey UMF 5+ | Shop online & save at NZs favourite online health store. Enjoy fast, often free delivery NZ & worldwide!
http://www.healthpost.co.nz/arataki-honey-manuka-honey-umf-5-atkm5-g.html
Our Process | WildCape Manuka HoneyOur Process | WildCape Manuka Honey
WildCapes Manuka honey is 100% pure honey from the unspoilt East Cape of New Zealand. All our honey is UMF certified and produced to the highest standards.
https://wildcapehoney.co.nz/quality-guarantee/
Manuka Honey | Oha Honey | Online StoreManuka Honey | Oha Honey | Online Store
New Zealands finest Manuka Honey online shop. Molan Gold Standard™ certified. Pure sourced ingredients. Fast worldwide shipping. Secure payment processing.
https://ohahoney.com/
Raw Manuka Honey Treat Herpes
Manuka honey is one of the best remedies for herpes. Its antibiotic and antiviral properties help in killing the virus and reduces the further outbreaks.
http://manukahoneyblog.com/raw-manuka-honey-treat-herpes/
Cardiac-glycosides and Their Metabolites Levels in Plasma and Heart of Guinea-pigs After Iv Administration | DIAL.pr - BOREALCardiac-glycosides and Their Metabolites Levels in Plasma and Heart of Guinea-pigs After Iv Administration | DIAL.pr - BOREAL
Dolphen, R. ; Lesne, Michel. Cardiac-glycosides and Their Metabolites Levels in Plasma and Heart of Guinea-pigs After Iv Administration. In: Archives Internationales de Pharmacodynamie et de Therapie, Vol. 251, no. 1, p. 4-25 (1981 ...
https://dial.uclouvain.be/pr/boreal/object/boreal:58173
Manuka Honey
By using our website, you agree to the use of cookies. These cookies help us understand how customers arrive at and use our site and help us make improvements. Hide this message More on cookies » ...
https://www.victoriashealth.com/greens-whole-foods/super-fooods/manuka-honey/
Intravenous administration of STAg causes production of | Open-iIntravenous administration of STAg causes production of | Open-i
Intravenous administration of STAg causes production of IL-12 p40 that can prime an IFN-γ response. (A) Spontaneous IL-12 production by spleen cells isolated
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199158_JEM.971614f2b&req=4
IvWatch: A Technology That Detects Leakage Of IV Fuid Outside The VeinIvWatch: A Technology That Detects Leakage Of IV Fuid Outside The Vein
The device can reliably detect 4cc leakage, increases nursing productivity and works with both forearm and back of the hand that are IV administration sites.
http://www.medindia.net/news/ivwatch-detects-leakage-outside-veins-in-iv-therapy-148223-1.htm
Structure Cluster - 1H2A: SINGLE CRYSTALS OF HYDROGENASE FROM DESULFOVIBRIO VULGARIS 3D Similarity Report PageStructure Cluster - 1H2A: SINGLE CRYSTALS OF HYDROGENASE FROM DESULFOVIBRIO VULGARIS 3D Similarity Report Page
1H2A: Unusual ligand structure in Ni-Fe active center and an additional Mg site in hydrogenase revealed by high resolution X-ray structure analysis.
http://www.rcsb.org/pdb/explore/structureCluster.do?structureId=1H2A
Intravenous ascorbic acidIntravenous ascorbic acid
According to the U.S. Food and Drug Administration (FDA), high-dose vitamin C (such as intravenous ascorbic acid therapy) has ... Mikirova N, Casciari J, Riordan N, Hunninghake R (August 2013). "Clinical experience with intravenous administration of ... The use of intravenous ascorbic acid in the treatment of cancer has been a contentious issue. There is no evidence to indicate ... The use of intravenous ascorbic acid as a proposed cancer treatment or co-treatment has been a controversial topic since the ...
https://en.wikipedia.org/wiki/Intravenous_ascorbic_acid
Y-Set (intravenous therapy)Y-Set (intravenous therapy)
Intravenous fluids, Medical equipment, Routes of administration). ... In intravenous therapy a Y-Set, T-Set and V-Sets are Y, T and V shaped three-way connector sets made of connecting plastic ... to a short common limb attached to the female fitting on the intravenous cannulae. 3-way connectors allow for "piggybacking", ... tubes used for delivering intravenous drugs into the body from multiple fluid sources. As Y-Sets are the most common shaped ...
https://en.wikipedia.org/wiki/Y-Set_(intravenous_therapy)
Total intravenous anaesthesiaTotal intravenous anaesthesia
Total intravenous anesthesia (TIVA) refers to the intravenous administration of anesthetic agents to induce a temporary loss of ... Secondly, intravenous delivery may be impaired by lax monitoring of the intravenous catheter and the insertion site. Thirdly, ... Engbers, Frank H. M. (2000), "Total Intravenous Anaesthesia: The Equipment", On the Study and Practice of Intravenous ... Sepúlveda V., Pablo O.; Cortínez, Luis Ignacio (2017), "Intravenous Anesthesia in Obese Patients", Total Intravenous Anesthesia ...
https://en.wikipedia.org/wiki/Total_intravenous_anaesthesia
Intravenous iron infusionIntravenous iron infusion
Auerbach, M., Ballard, H. (2010). 'Clinical Use of Intravenous Iron: Administration, Efficacy, and Safety,' ASH Education Book ... In intravenous iron infusions, free iron has been shown to potentiate bacterial growth. Evidence associated with intravenous ... These findings show that intravenous iron has a broad use to many patients where anaemia is an underlying issue. Intravenous ... The intravenous method is a fast and effective way of delivering iron throughout the body, and is used because iron can be ...
https://en.wikipedia.org/wiki/Intravenous_iron_infusion
Potomac horse feverPotomac horse fever
... intravenous dimethyl sulfoxide; administration of products such as Biosponge or activated charcoal via nasogastric tube to bind ... This may include intravenous fluids and electrolytes to counteract the diarrhea; NSAIDs such as Banamine (flunixin meglumine); ... Mild cases may be treated with oral doxycycline, while severe cases are usually treated with intravenous oxytetracycline. ... Experimental infection has been produced with oral administration of infected insects and subcutaneous inoculation of N. ...
https://en.wikipedia.org/wiki/Potomac_horse_fever
Immunoglobulin therapyImmunoglobulin therapy
"Laboratory Serologic Problems Associated with Administration of Intravenous IgG". The University of Texas M. D. Anderson Cancer ... August 2008). "Hemolytic transfusion reactions after administration of intravenous immune (gamma) globulin: a case series ... subcutaneous administration but still a lower frequency of adverse effects when compared to intravenous administration). ... Brands include Asceniv (immune globulin intravenous, human - slra) Bivigam (immune globulin intravenous - human 10% liquid) ...
https://en.wikipedia.org/wiki/Immunoglobulin_therapy
MetaraminolMetaraminol
... is commonly available as 10mg in 1mL, that requires dilution prior to administration (often made up to a 0.5mg/mL ... Kee VR (August 2003). "Hemodynamic pharmacology of intravenous vasopressors". Crit Care Nurse. 23 (4): 79-82. doi:10.4037/ ... "ANDA APPROVAL FOR METARAMINOL" (PDF). United States Food and Drug Administration. 24 August 2021. Retrieved 13 August 2022.{{ ... "Injection : Aramine (Metaraminol Bitartrate)" (PDF). U.S. Food and Drug Administration (FDA). Retrieved 12 March 2022. ...
https://en.wikipedia.org/wiki/Metaraminol
Sipuleucel-TSipuleucel-T
... was approved by the U.S. Food and Drug Administration (FDA) on April 29, 2010, to treat asymptomatic or minimally ... "Sipuleucel-T (Intravenous Route) - Side Effects". Mayo Clinic. Retrieved 22 April 2015. "Package Insert and Patient Information ... "Provenge (sipuleucel-T)". U.S. Food and Drug Administration. 14 July 2017. Archived from the original on 22 July 2017. ... "Provenge (sipuleucel-T)". U.S. Food and Drug Administration. 22 July 2017. Retrieved 1 April 2020. Plosker GL (January 2011). " ...
https://en.wikipedia.org/wiki/Sipuleucel-T
Piflufolastat F-18Piflufolastat F-18
It is the second PSMA-targeted PET imaging drug approved by the U.S. Food and Drug Administration (FDA). The first approved ... It is given by intravenous injection. The most common adverse reactions include headache, altered taste, and fatigue. ... "FDA approves PSMA-targeted imaging drug for men with prostate cancer". U.S. Food and Drug Administration (FDA). 27 May 2021. ... The U.S. Food and Drug Administration (FDA) granted approval of Pylarify to Progenics Pharmaceuticals, Inc. "Pylarify- ...
https://en.wikipedia.org/wiki/Piflufolastat_F-18
PeramivirPeramivir
It is approved for intravenous administration. In October 2009, the U.S. Food and Drug Administration (FDA) issued an emergency ... for intravenous peramivir in December 2013. Peramivir (Rapivab) was approved for intravenous administration in December 2014. " ... effective in intravenous treating 8 serious cases of swine flu. On October 23, the U.S. Food and Drug Administration (FDA) ... "Peramivir: Requirements for Administration under EUA". Lifehugger. Archived from the original on 2011-07-13. "CDC H1N1 Flu - ...
https://en.wikipedia.org/wiki/Peramivir
OcrelizumabOcrelizumab
It was approved by the U.S. Food and Drug Administration (FDA) in March 2017, and the first FDA approved drug for the primary ... It is administered by intravenous infusion. In the EU, ocrelizumab is indicated for the treatment of adults with relapsing ... The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. In the US, ocrelizumab is indicated ... "BLA Approval Letter" (PDF). U.S. Food and Drug Administration (FDA). March 28, 2017. New Drug Therapy Approvals 2017 (PDF). U.S ...
https://en.wikipedia.org/wiki/Ocrelizumab
VX (nerve agent)VX (nerve agent)
"Intravenous Administration of VX in Man". Archived from the original on March 26, 2017. Retrieved 2017-03-25.{{cite web}}: CS1 ... Van M. Sim underwent an intravenous infusion of VX to evaluate its effects and to establish a baseline for future ... After approximately 3.5 hours following initial administration of the agent, Sim suddenly became pale and delirious. The ...
https://en.wikipedia.org/wiki/VX_(nerve_agent)
Intravenous sodium bicarbonateIntravenous sodium bicarbonate
Rapid administration (equal to or exceeding 10 mL/min) of intravenous sodium bicarbonate into neonates and children under two ... Norepinephrine and dobutamine cannot be used as additives in an intravenous sodium bicarbonate solution. Intravenous sodium ... Intravenous medical use began around the 1950s. It is on the World Health Organization's List of Essential Medicines. Sodium ... Intravenous sodium bicarbonate is indicated in the treatment of metabolic acidosis, such as can occur in severe kidney disease ...
https://en.wikipedia.org/wiki/Intravenous_sodium_bicarbonate
PhenylephrinePhenylephrine
"Vazculep Package Insert" (PDF). U.S. Food and Drug Administration. Shih JC, Chen K (August 2004). "Regulation of MAO-A and MAO- ... The clinical effects of a single intravenous bolus dose of phenylephrine are short lived and needs to be repeated every 10-15 ... Commonly the drug is given as a carefully titrated intravenous infusion with a syringe pump or volumetric pump. Because of its ... Compared to intravenous pseudoephedrine, phenylephrine has a reduced and variable bioavailability; only up to 38%. " ...
https://en.wikipedia.org/wiki/Phenylephrine
AnidulafunginAnidulafungin
Food and Drug Administration. 2006-02-21. Archived from the original on 10 July 2009. Retrieved 2009-08-01. (Webarchive ... "Eraxis (anidulafungin) for Injection, for Intravenous Use. Full Prescribing Information". Roerig (Division of Pfizer, Inc.), ... Trissel LA and Ogundele AB, "Compatibility of Anidulafungin With Other Drugs During Simulated Y-Site Administration,"Am J ... Pfizer gained approval by the Food and Drug Administration (FDA) on February 21, 2006. "International Nonproprietary Names for ...
https://en.wikipedia.org/wiki/Anidulafungin
AmrinoneAmrinone
Currently, only acute intravenous administration takes place. The effects of amrinone vary widely with species and experimental ... An IV administration of amrinone has been shown to increase cardiac output (CO) and stroke volume (SV), while concurrently ... Klein N.A.; Siskind S.J.; Frishman W.H.; Sonnelblick E.H.; LeJemtel T.H. (1981). "Hemodynamic Comparison of Intravenous ... An increase in cAMP with the administration of amrinone in vascular smooth muscle produces vasodilation by facilitating calcium ...
https://en.wikipedia.org/wiki/Amrinone
NitroglycerinNitroglycerin
"Association of methemoglobinemia and intravenous nitroglycerin administration". American Journal of Cardiology. 55 (1): 181-183 ... The Occupational Safety and Health Administration has set the legal limit (permissible exposure limit) for nitroglycerin ... Nitroglycerin is available in tablets, ointment, solution for intravenous use, transdermal patches, or sprays administered ...
https://en.wikipedia.org/wiki/Nitroglycerin
MetronidazoleMetronidazole
Intravenous administration is commonly associated with thrombophlebitis. Infrequent adverse effects include: hypersensitivity ... suppositories and intravenous administration". Scandinavian Journal of Gastroenterology. Supplement. 91: 45-60. PMID 6588489. ... The U.S. Food and Drug Administration (FDA) suggests it only be used when necessary because it has been shown to be ... The serum half-life of hydroxymetronidazole after suppository was 10 hours, 19 hours after intravenous infusion, and 11 hours ...
https://en.wikipedia.org/wiki/Metronidazole
Nitroglycerin (medication)Nitroglycerin (medication)
"Association of methemoglobinemia and intravenous nitroglycerin administration". The American Journal of Cardiology. 55 (1): 181 ... Continuous administration and absorption (such as provided by daily pills and especially skin patches) accelerate onset of ...
https://en.wikipedia.org/wiki/Nitroglycerin_(medication)
Purple glove syndromePurple glove syndrome
"Purple glove syndrome following intravenous phenytoin administration". Vasc Med. 12 (1): 29-31. doi:10.1177/1358863X07076551. ... Onset is generally seen within the first few hours of administration. The true pathology of purple glove syndrome is not fully ... PGS is most common among elderly patients and those receiving multiple large intravenous doses of the epilepsy drug phenytoin. ... This may occur due to the administration of phenytoin with or without extravasation. The defining characteristic is a purplish ...
https://en.wikipedia.org/wiki/Purple_glove_syndrome
Absorption (pharmacology)Absorption (pharmacology)
Absorption is the journey of a drug travelling from the site of administration to the site of action. The drug travels by some ... A common example is bolus intravenous injection. Zero-order absorption: rate of absorption is constant. A common example is ... Representative examples include typical cases of oral administration, subcutaneous injection, and intramuscular injection. ... Intravascular administration does not involve absorption, and there is no loss of drug. The fastest route of absorption is ...
https://en.wikipedia.org/wiki/Absorption_(pharmacology)
Group B streptococcal infectionGroup B streptococcal infection
Administration of intravenous (IV) antibiotics during labour. Intravenous penicillin or ampicillin given at the onset of labour ... Where insufficient intravenous antibiotics are given before delivery, the baby may be given antibiotics immediately after birth ... If the woman has a severe allergy to beta-lactams then intravenous vancomycin (1 g every 12 hours) is recommended. Neither ... Currently, the only reliable way to prevent GBS-EOD is administration of intrapartum antibiotics before delivery, that is to ...
https://en.wikipedia.org/wiki/Group_B_streptococcal_infection
Route of administrationRoute of administration
Intravaginal administration, in the vagina. Intravenous (into a vein), e.g. many drugs, total parenteral nutrition. ... Common examples include oral and intravenous administration. Routes can also be classified based on where the target of action ... Oral administration is often denoted "PO" from "per os", the Latin for "by mouth". The bioavailability of oral administration ... Comparative biopharmaceutics of diazepam after single rectal, oral, intramuscular and intravenous administration in man". ...
https://en.wikipedia.org/wiki/Route_of_administration
Decompression illnessDecompression illness
Administration of intravenous saline solution is preferable. Record details of recent dives and responses to first aid ...
https://en.wikipedia.org/wiki/Decompression_illness
MeloxicamMeloxicam
... after oral administration and a mean volume of distribution at steady-state of 0.2 L/kg after intravenous administration." " ... "Anjeso (meloxicam) injection, for intravenous use" (PDF). U.S. Food and Drug Administration (FDA). February 2020. Archived (PDF ... An intravenous version of meloxicam (Anjeso) was approved for medical use in the United States in February 2020. Meloxicam use ... Perioperative administration of meloxicam to cats did not affect postoperative respiratory rate nor heart rate. A peer-reviewed ...
https://en.wikipedia.org/wiki/Meloxicam
Giant-cell tumor of boneGiant-cell tumor of bone
The mass enhances after intravenous gadolinium administration. A number of tumors have giant cells, but are not true benign ...
https://en.wikipedia.org/wiki/Giant-cell_tumor_of_bone
Jason DiamondJason Diamond
Comparing Intranasal Administration to Intramuscular Administration in Healthy Human Volunteers." University of Kentucky ... Intravenous Botorphanol Tartrate In Healthy Human Volunteers." University of Kentucky Chandler Medical Center Protocol BT002. " ...
https://en.wikipedia.org/wiki/Jason_Diamond
Packed red blood cellsPacked red blood cells
February 2018). "The administration of blood components: a British Society for Haematology Guideline". Transfusion Medicine. 28 ... Plumer AL (2007). Plumer's Principles and Practice of Intravenous Therapy. Lippincott Williams & Wilkins. p. 423. ISBN ...
https://en.wikipedia.org/wiki/Packed_red_blood_cells
Brit milahBrit milah
Berger, Itai; Steinberg, Avraham (May 2002). "Neonatal mydriasis: intravenous lidocaine adverse reaction". J Child Neurol. 17 ( ... "Generalized seizures following topical lidocaine administration during circumcision: establishing causation". Paediatr Drugs. 9 ...
https://en.wikipedia.org/wiki/Brit_milah
Pregnancy categoryPregnancy category
Food and Drug Administration. April 1, 1997. Archived from the original on 2008-03-26. Retrieved 2008-05-21. (All articles with ... Appendix 4 is now titled "Intravenous Additives". However, information that was previously available in the former Appendix 4 ( ... Food and Drug Administration. Federal Register 1980; 44:37434-67 "Specific requirements on content and format of labeling for ... "Prescribing medicines in pregnancy database". Therapeutic Goods Administration (TGA). 2021-04-15. Retrieved 2021-08-16.{{cite ...
https://en.wikipedia.org/wiki/Pregnancy_category
Cervical cancerCervical cancer
On 15 June 2006, the US Food and Drug Administration approved the use of a combination of two chemotherapy drugs, hycamtin and ... intravenous urography, and X-ray examination of the lungs and skeleton, and cervical conization. However, the current system ... In 2006, the U.S. Food and Drug Administration (FDA) approved the first preventive HPV vaccine, marketed by Merck & Co. under ... "FDA Approves First Drug Treatment for Late-Stage Cervical Cancer". U.S. Food and Drug Administration. 15 June 2006. Archived ...
https://en.wikipedia.org/wiki/Cervical_cancer
NorovirusNorovirus
Management involves supportive care such as drinking sufficient fluids or intravenous fluids. Oral rehydration solutions are ... polymerase chain reaction are being employed by governmental laboratories such as the Food and Drug Administration (FDA) in the ...
https://en.wikipedia.org/wiki/Norovirus
ChildbirthChildbirth
Active management is the administration of a uterotonic drug within one minute of fetal delivery, controlled traction of the ... or with a combination of prostaglandin and intravenous oxytocin treatment. Caesarean section is the removal of the neonate ... Lancashire, Liz (9 July 2018). "Medicine Administration for Midwives". Norfolk and Norwich University Hospitals. Archived from ... but instead to postponing delivery long enough for the administration of glucocorticoids which can help the fetal lungs to ...
https://en.wikipedia.org/wiki/Childbirth
Pre-exposure prophylaxisPre-exposure prophylaxis
... intravenous drug users, men who have sex with men) without consistent condom use or anyone who has injected illicit drugs in ... the US Food and Drug Administration (FDA) approved the combination of emtricitabine and tenofovir alafenamide (Descovy) to be ... or has been in treatment for intravenous drug use in the past six months In the United Kingdom the BHIVA/BASHH guidelines on ... people who engage in intravenous drug use (see drug injection), and serodiscordant sexually active couples. When used as ...
https://en.wikipedia.org/wiki/Pre-exposure_prophylaxis
2022 monkeypox outbreak2022 monkeypox outbreak
... the General Administration of Customs of the People's Republic of China issued the Announcement on Preventing Monkeypox from ... suggests supportive care may typically be sufficient and that several antivirals and vaccinia immune globulin intravenous ( ... General office of the National Health Commission of the People's Republic of China and the Office of the State Administration ...
https://en.wikipedia.org/wiki/2022_monkeypox_outbreak
LormetazepamLormetazepam
Repeated administration and transfer to neonates via breast milk". European Journal of Clinical Pharmacology. 21 (5): 421-5. ... June 1996). "Intravenous flumazenil following prolonged exposure to lormetazepam in humans: lack of precipitated withdrawal". ... effects after nighttime administration of lormetazepam such as sleepiness, impaired psychomotor and cognitive functions may ...
https://en.wikipedia.org/wiki/Lormetazepam
John Abner SnellJohn Abner Snell
Under his administration, the Soochow Hospital underwent a large expansion, acquired modern technology, and was held to a very ... They implemented a variety of treatment techniques, primarily intravenous Rogers treatment of saline solution. Snell also ... Additionally, administration obtained a new X-ray machine which greatly improved the hospital's ability for diagnosis. On ... Upon Park's return, the responsibilities were split, leaving Snell responsible for surgery and administration. Main concerns ...
https://en.wikipedia.org/wiki/John_Abner_Snell
PembrolizumabPembrolizumab
30 May 2017). "FDA D.I.S.C.O.: First Tissue/Site Agnostic Approval Transcript". U.S. Food and Drug Administration (FDA). ... As of 2019[update], pembrolizumab is used via intravenous infusion to treat inoperable or metastatic melanoma, metastatic non- ... "FDA approves pembrolizumab for adults and children with TMB-H solid tumors". U.S. Food and Drug Administration (FDA). 17 June ... "FDA approves first cancer treatment for any solid tumor with a specific genetic feature". U.S. Food and Drug Administration ( ...
https://en.wikipedia.org/wiki/Pembrolizumab
Oral candidiasisOral candidiasis
... depending on the route of administration. Topically administered corticosteroids in the mouth may take the form of mouthwashes ... may require systemic prevention or treatment with oral or intravenous administered anti-fungals. However, there is strong ...
https://en.wikipedia.org/wiki/Oral_candidiasis
LevothyroxineLevothyroxine
... for systemic administration is available as an oral tablet, an intramuscular injection, and as a solution for ... Levothyroxine is taken by mouth or given by intravenous injection. Maximum effect from a specific dose can take up to six weeks ... According to the U.S. Food and Drug Administration pregnancy categories, levothyroxine has been assigned category A. Given that ... Food and Drug Administration (FDA). 19 November 2020. Portal: Medicine (CS1 German-language sources (de), Articles with short ...
https://en.wikipedia.org/wiki/Levothyroxine
Polyestriol phosphatePolyestriol phosphate
Intravenous administration of ovarian hormones offers no advantages, however, and therefore has no practical significance ... The following duarations of action have been obtained with a single administration (WlED, 1954; LAURITZEN, 1968): [...] 50 mg ...
https://en.wikipedia.org/wiki/Polyestriol_phosphate
Aspiration pneumoniaAspiration pneumonia
The administration of anesthesia causes suppression of protective reflexes, most importantly the gag reflex. As a result, ... ranging from topical antibiotics to intravenous antibiotic use. Whereas the use of antibiotics focuses on destroying and ...
https://en.wikipedia.org/wiki/Aspiration_pneumonia
Hyperosmolar syndromeHyperosmolar syndrome
Following the administration of intravenous insulin, dextrose should be added once glucose levels reach the 250-300mg/dL target ... Treatment involves intravenous fluids to replenish hydration- reducing plasma, intravenous insulin to lower blood sugar levels ... and intravenous potassium and sodium to replace the lost electrolytes which are essential for cell function, as insulin will ...
https://en.wikipedia.org/wiki/Hyperosmolar_syndrome
OxycodoneOxycodone
... of the analgesic effect of oxycodone after oral and intravenous administration, respectively. Although the CYP2D6 genotype and ... The bioavailability of oral administration of oxycodone averages within a range of 60 to 87%, with rectal administration ... of its analgesic effect following oral and intravenous administration, respectively. Oxymorphone plays only a minor role, being ... Therapeutic Goods Administration (June 2008). Standard for the uniform scheduling of drugs and poisons no. 23 (PDF). Canberra: ...
https://en.wikipedia.org/wiki/Oxycodone
Lyme diseaseLyme disease
Intravenous administration of ceftriaxone is recommended as the first choice in these cases; cefotaxime and doxycycline are ... intravenous and intramuscular penicillin and intravenous ceftriaxone. The mechanism of tick transmission was also the subject ... It was granted fast track designation by the U.S. Food and Drug Administration in July 2017. In April 2020 Pfizer paid $130 ... On 21 December 1998, the Food and Drug Administration (FDA) approved LYMErix on the basis of these trials for persons of ages ...
https://en.wikipedia.org/wiki/Lyme_disease
PharmacosmosPharmacosmos
Its approved by health authorities in Europe, Asia and in the U.S. by Food and Drug Administration (FDA). Pharmacosmos is one ... NCT01145638 Sinha, S.; Kalra, P. (2010). "Treating the Anemic Oncology Patient with Intravenous Iron: Why, When, and How?" (PDF ... Food and Drug Administration (FDA). The company has an ongoing clinical development program aimed at improving treatment ...
https://en.wikipedia.org/wiki/Pharmacosmos
Essendon Football Club supplements sagaEssendon Football Club supplements saga
The program also included supplements in pill form and intravenous vitamin drips. The program was intended to be leading-edge, ... but it had not been approved for human use by the Therapeutic Goods Administration and therefore could be considered as banned ... and many features of the program which were legal at the time, including Tribulus and intravenous vitamin C, were outlawed by ... "deplorable absence of records in the program relating to its administration." Essendon and the AFL discussed and negotiated ...
https://en.wikipedia.org/wiki/Essendon_Football_Club_supplements_saga
DoxepinDoxepin
Slow intravenous administration of physostigmine may reverse some of the toxic effects of overdose such as anticholinergic ... Management of overdose is mostly supportive and symptomatic, and can include the administration of a gastric lavage so as to ... "Sleep Disorder (Sedative-Hypnotic) Drug Information - U.S. FDA". Food and Drug Administration. 13 June 2017. Retrieved 9 August ...
https://en.wikipedia.org/wiki/Doxepin
FlumazenilFlumazenil
Intravenous flumazenil is primarily used to treat benzodiazepine overdoses and to help reverse anesthesia. Administration of ... Administration of the drug requires careful monitoring by an anesthesiologist due to potential side effects and serious risks ... Intravenous flumazenil has been shown to antagonize sedation, impairment of recall, psychomotor impairment and ventilatory ... It is available as a clear, colourless solution for intravenous injection, containing 500 μg in 5 mL. Many benzodiazepines ( ...
https://en.wikipedia.org/wiki/Flumazenil
CX717CX717
In 2005 the U.S. Food and Drug Administration (FDA) accepted Cortex Pharmaceuticals' Investigational New Drug (IND) application ... effects of the ampakine drugs on the pre-Botzinger complex of the brain has led to continued development of an intravenous ... "Brain Vacuolation Resulting From Administration of the Type II Ampakine CX717 Is An Artifact Related to Molecular Structure and ...
https://en.wikipedia.org/wiki/CX717
Effects of cannabisEffects of cannabis
March 2015). "How cannabis causes paranoia: using the intravenous administration of ∆9-tetrahydrocannabinol (THC) to identify ... Furthermore, even in those with no family history of psychosis, the administration of pure THC in clinical settings has been ... August 2004). "The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for ... Department of Transportation's National Highway Traffic Safety Administration, it was found that other "studies that measure ...
https://en.wikipedia.org/wiki/Effects_of_cannabis
Physiologically based pharmacokinetic modellingPhysiologically based pharmacokinetic modelling
Intravenous injection is a common clinical route of administration. (to be completed) Inhalation occurs through the lung and is ... these models also facilitate inter-species transpositions or extrapolation from one mode of administration to another (e.g., ... or single to multiple exposures Routes of administration: e.g., from inhalation exposures to ingestion Species: e.g., ...
https://en.wikipedia.org/wiki/Physiologically_based_pharmacokinetic_modelling
VoriconazoleVoriconazole
... allowing patients to be switched between intravenous and oral administration. Pfizer brought the drug to market as Vfend. A ... It can be taken by mouth or given in a doctor's office or clinic by intravenous infusion. It is toxic to the fetus; pregnant ...
https://en.wikipedia.org/wiki/Voriconazole
Alpha-1 antitrypsinAlpha-1 antitrypsin
These products for intravenous augmentation A1AT therapy can cost up to $100,000 per year per patient. They are administered ... The US Food and Drug Administration (FDA) has approved the use of four alpha-1 antitrypsin products derived from a human plasma ... "Aralast NP". U.S. Food and Drug Administration (FDA). 22 July 2017. Retrieved 11 May 2020. "Aralast". U.S. Food and Drug ... "Prolastin". U.S. Food and Drug Administration (FDA). 5 March 2018. Retrieved 11 May 2020. "Prolastin-C". U.S. Food and Drug ...
https://en.wikipedia.org/wiki/Alpha-1_antitrypsin
BiodylBiodyl
Adverse effect Intravenous therapy Electrolyte Oral rehydration therapy Polo pony Endurance riding "BIODYL" (PDF). M.C.I. Santé ... "Refusal Details as Recorded in OASIS by FDA for Refusal 112-4397009-5/1/1/". Food and Drug Administration. Retrieved 2009-06-14 ... U.S. Food and Drug Administration. July 8, 2003. Archived from the original on January 15, 2008. Retrieved April 24, 2009. ... The Associated Press reported erroneously that the Food and Drug Administration had refused to approve the French-made ...
https://en.wikipedia.org/wiki/Biodyl
CopanlisibCopanlisib
... at ClinicalTrials.gov Food and Drug Administration. "Drug Trials Snapshots ALIQOPA". www.fda.gov. Food and Drug Administration ... Copanlisib is administered as intravenous infusion on a weekly but intermittent schedule (three weeks on and one week off). ... Food and Drug Administration. "NDA 209936, Approval Letter" (PDF). www.fda.gov. Clinical trial number NCT02728258 for " ... "FDA Prescribing information for Aliqopa" (PDF). Food and Drug Administration. "FDA News Alert: FDA approves new treatment for ...
https://en.wikipedia.org/wiki/Copanlisib
PheochromocytomaPheochromocytoma
... intravenous hydrocortisone in the operating room prior to anesthesia Repeat administration of 25-50 mg intravenous ... Furthermore, the intravenous contrast used in CT can cause kidney damage and should therefore be avoided in patients with pre- ... Some institutions in the United States will even admit patients the night prior to surgery for intravenous fluid replacement ... However, a small trial from 2009 reported no difference in mortality in patients treated with preoperative intravenous fluids ...
https://en.wikipedia.org/wiki/Pheochromocytoma
PsychotomimetismPsychotomimetism
2004) found that intravenous THC produced effects that resemble schizophrenia in both the positive symptoms (hallucinations, ... Psychotomimesis is the onset of psychotic symptoms following the administration of such a drug. Some rarely used drugs of the ... "The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis" ( ...
https://en.wikipedia.org/wiki/Psychotomimetism
BioCryst PharmaceuticalsBioCryst Pharmaceuticals
1 clinical safety and pharmacokinetics trials conducted in 2019 by both intravenous and intramuscular routes of administration ...
https://en.wikipedia.org/wiki/BioCryst_Pharmaceuticals
Dexamethasone suppression testDexamethasone suppression test
... with the cortisol level measured 6 hours after the final dose was given Intravenous DST Dexamethasone-CRT test Low-dose and ... A normal result is a decrease in cortisol levels upon administration of low-dose dexamethasone. Results indicative of Cushing's ...
https://en.wikipedia.org/wiki/Dexamethasone_suppression_test
Notes from the Field: Adverse Events Associated with Administration of Simulation Intravenous Fluids to Patients - United...Notes from the Field: Adverse Events Associated with Administration of Simulation Intravenous Fluids to Patients - United...
Notes from the Field: Adverse Events Associated with Administration of Simulation Intravenous Fluids to Patients - United ... A sample of the simulated saline product inadvertently administered to multiple patients as sterile intravenous fluid, with ... Simultaneously, the Food and Drug Administration issued an alert, warning health care professionals not to use any Wallcur ... Both patients experienced a febrile illness during product administration and were hospitalized; one patient developed sepsis ...
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6408a6.htm?s_cid=mm6408a6_w
Pharmacokinetics and pharmacodynamics of the hydroxymetabolite of glimepiride (Amaryl) after intravenous administrationPharmacokinetics and pharmacodynamics of the hydroxymetabolite of glimepiride (Amaryl) after intravenous administration
... Drug ... 12 healthy male volunteers received an intravenous injection of hydroxy-gli (1.5 mg) or placebo in a single blind, randomised, ... Samples were collected for up to 24 hours (blood) or 48 hours (urine) following administration of hydroxy-gli or placebo. ...
https://pubmed.ncbi.nlm.nih.gov/8902432/?dopt=Abstract
Octagam intravenous immunoglobulin solutions | Therapeutic Goods Administration (TGA)Octagam intravenous immunoglobulin solutions | Therapeutic Goods Administration (TGA)
Although thromboembolic events are a known rare adverse event associated with the administration of all intravenous ... The Therapeutic Goods Administration (TGA) advises that Octapharma Australia Pty Ltd has agreed to a precautionary voluntary ... and health care providers should report any adverse events that have occurred following administration of Octagam intravenous ... As a result of this decision, all stock of Octagam intravenous immunoglobulin solutions in Australia will be recalled ...
https://www.tga.gov.au/octagam-intravenous-immunoglobulin-solutions
Exposure-Response Analyses of Letermovir Following Oral and Intravenous Administration in Allogeneic Hematopoietic Cell...Exposure-Response Analyses of Letermovir Following Oral and Intravenous Administration in Allogeneic Hematopoietic Cell...
Exposure-Response Analyses of Letermovir Following Oral and Intravenous Administration in Allogeneic Hematopoietic Cell ...
https://www.merck.com/publication/exposure-response-analyses-of-letermovir-following-oral-and-intravenous-administration-in-allogeneic-hematopoietic-cell-transplantation-recipients/
Efficacy and Safety of Intracoronary versus Intravenous Administration of Tirofiban during Percutaneous Coronary Intervention...Efficacy and Safety of Intracoronary versus Intravenous Administration of Tirofiban during Percutaneous Coronary Intervention...
... tirofiban administration for ACS patients undergoing PCI compared with intravenous (IV) administration. Therefore, this meta- ... IC administration of tirofiban significantly increased TIMI grade 3 flow (OR 2.11; 95% CI 1.02 to 4.37; P = 0.04) and TMP grade ... Conclusions This meta-analysis supports the use of IC over IV administration of tirofiban in patients with ACS to improve TIMI ... Methods We searched PubMed and Medline for randomized controlled trials (RCTs) comparing IC versus IV administration of ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129718
Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I...Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I...
... and efficacy non-inferior to standard intravenous administration, with a similar safety profile to intravenous trastuzumab, and ... Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I- ... Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I- ... Comparison of subcutaneous and intravenous administration of trastuzumab: a phase I/Ib trial in healthy male volunteers and ...
https://www.thelancet.com/journals/lancet/article/PIIS1470-2045%2812%2970329-7/fulltext
Erowid.org: Erowid Reference 7223 : Gamma-hydroxybutyric acid decreases intravenous cocaine self-administration in rats :...Erowid.org: Erowid Reference 7223 : Gamma-hydroxybutyric acid decreases intravenous cocaine self-administration in rats :...
Fratta W Gamma-hydroxybutyric acid decreases intravenous cocaine self-administration in rats Pharmacol Biochem Behav 1998 59(3 ... "Gamma-hydroxybutyric acid decreases intravenous cocaine self-administration in rats". Pharmacol Biochem Behav. 1998 Mar 05;59(3 ... "Gamma-hydroxybutyric acid decreases intravenous cocaine self-administration in rats" Pharmacol Biochem Behav. 1998 Mar 05;59(3 ... route of administration, and type of operant response required. These results indicate that GHB reduces cocaine-seeking ...
https://erowid.org/references/refs_view.php?ID=7223&S=GHB%20drug
CPT® Code - Injection and Intravenous Infusion Chemotherapy and Other Highly Complex Drug or Highly Complex Biologic Agent...CPT® Code - Injection and Intravenous Infusion Chemotherapy and Other Highly Complex Drug or Highly Complex Biologic Agent...
... code range for Injection and Intravenous Infusion Chemotherapy and Other Highly Complex Drug or Highly Comple ... Injection and Intravenous Infusion Chemotherapy and Other Highly Complex Drug or Highly Complex Biologic Agent Administration ... Injection and Intravenous Infusion Chemotherapy and Other Highly Complex Drug or Highly Complex Biologic Agent Administration ... code range for Chemotherapy Administration and Other Highly Complex Drug or Highly Complex Biologic Agent Administration 96401- ...
https://www.aapc.com/codes/cpt-codes-range/96401-96417/
Intravenous Steroid Days and Predictors of Early Oral Steroid Administration in Tuberculous Meningitis: A Retrospective Study...Intravenous Steroid Days and Predictors of Early Oral Steroid Administration in Tuberculous Meningitis: A Retrospective Study...
Intravenous (IV) dexamethasone is recommended for 14 days in stage 1 and 28 days in stage 2/3 tuberculous meningitis (TBM). We ... Intravenous Steroid Days and Predictors of Early Oral Steroid Administration in Tuberculous Meningitis: A Retrospective Study ... used intravenous (IV) dexamethasone for 2 weeks, and for stage 2 and 3 TBM, they used IV dexamethasone for 4 weeks. Intravenous ... Corticosteroids (dexamethasone versus intravenous methylprednisolone) in patients with tuberculous meningitis. Ann Trop Med ...
https://www.ajtmh.org/view/journals/tpmd/101/5/article-p1083.xml?rskey=vL23pd&result=1
Metabolism and disposition of [14C]dimethylamine borane in male Harlan Sprague Dawley rats following gavage administration,...Metabolism and disposition of [14C]dimethylamine borane in male Harlan Sprague Dawley rats following gavage administration,...
... dimethylamine borane in male Harlan Sprague Dawley rats following gavage administration, intravenous administration and dermal ... 2. Disposition of radioactivity was similar between gavage and intravenous administration of 1.5 mg/kg [14C] DMAB, with nearly ... but was higher than following the gavage or intravenous administration. 4. Following co-adminsitration of DMAB and sodium ... Metabolism and disposition of [14C]dimethylamine borane in male Harlan Sprague Dawley rats following gavage administration, ...
https://www.rti.org/publication/metabolism-and-disposition-14cdimethylamine-borane-male-harlan-sprague-dawley-rats
Influence of Surgery on the Pharmacokinetics of Tramadol Following Intravenous Administration in DogsInfluence of Surgery on the Pharmacokinetics of Tramadol Following Intravenous Administration in Dogs
... ... Influence of Surgery on the Pharmacokinetics of Tramadol Following Intravenous Administration in Dogs. Asian Journal of Animal ... A slightly higher t1/2α (0.32 h) was reported by Kukanich and Papich (2004) following i.v. administration of 4 mg kg-1 tramadol ... Therefore, re-administration of tramadol at 3 h is necessary for pain control. This suggests that surgery has a significant ...
https://scialert.net/fulltext/?doi=ajava.2013.483.492
PK/PD profiles of the CXCL8 decoy protein PA401 after intravenous and intratracheal administration in saline and LPS exposed...PK/PD profiles of the CXCL8 decoy protein PA401 after intravenous and intratracheal administration in saline and LPS exposed...
PK/PD profiles of the CXCL8 decoy protein PA401 after intravenous and intratracheal administration in saline and LPS exposed ... PK/PD profiles of the CXCL8 decoy protein PA401 after intravenous and intratracheal administration in saline and LPS exposed ... PK/PD profiles of the CXCL8 decoy protein PA401 after intravenous and intratracheal administration in saline and LPS exposed ... PK/PD profiles of the CXCL8 decoy protein PA401 after intravenous and intratracheal administration in saline and LPS exposed ...
https://erj.ersjournals.com/content/40/Suppl_56/P2139
Pharmacokinetics of meloxicam following intravenous and oral administration in green iguanas (Iguana iguana) in: American...Pharmacokinetics of meloxicam following intravenous and oral administration in green iguanas (Iguana iguana) in: American...
... administration. Time from administration to maximum plasma concentration and mean residence time were significantly longer ... Daily administration of high doses (1 or 5 mg/kg) for 12 days did not induce any histologic changes in gastric, hepatic, or ... Conclusions and Clinical Relevance-Results suggested that administration of meloxicam at a dose of 0.2 mg/kg IV or PO in green ... Results-There were no significant differences between PO and IV administration with regard to terminal half-life (mean ± SD, ...
https://avmajournals.avma.org/view/journals/ajvr/71/11/ajvr.71.11.1277.xml?rskey=tkYYfl&result=1
AID 60712 - Inhibitory activity against LTB4 production upon intravenous administration at a dose of 1.0 mg/Kg (0.25-0.5 hour)...AID 60712 - Inhibitory activity against LTB4 production upon intravenous administration at a dose of 1.0 mg/Kg (0.25-0.5 hour)...
Inhibitory activity against LTB4 production upon intravenous administration at a dose of 1.0 mg/Kg (0.25-0.5 hour) in dog ex ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/60712
Melanom: A phase I, first in human, two part, open-label clinical trial of intravenous administration of ctl-002 given as...Melanom: A phase I, first in human, two part, open-label clinical trial of intravenous administration of ctl-002 given as...
Melanom: A phase I, first in human, two part, open-label clinical trial of intravenous administration of ctl-002 given as ... A phase I, first in human, two part, open-label clinical trial of intravenous administration of ctl-002 given as monotherapy ...
https://www.usz.ch/studie/melanom-a-phase-i-first-in-human-two-part-open-label-clinical-trial-of-intravenous-administration-of-ctl-002-given-as-monotherapy-and-or-in-combination-with-an-anti-pd-1-checkpoint-inhibitor-in-su/
Intravenous naloxone administration in schizophrenia and affective illness<...
Intravenous naloxone administration in schizophrenia and affective illness. In: Science. 1977 ; Vol. 197, No. 4298. pp. 74-77. ... Intravenous naloxone administration in schizophrenia and affective illness. Glenn C. Davis, William E. Bunney, Emanuel G. ... Intravenous naloxone administration in schizophrenia and affective illness. Science. 1977 Jan 1;197(4298):74-77. doi: 10.1126/ ... Intravenous naloxone administration in schizophrenia and affective illness. / Davis, Glenn C.; Bunney, William E.; Defraites, ...
https://jhu.pure.elsevier.com/en/publications/intravenous-naloxone-administration-in-schizophrenia-and-affectiv
Intravenous Immunoglobulin: Overview, Uses of Intravenous Immunoglobulin, Pharmacology and MonitoringIntravenous Immunoglobulin: Overview, Uses of Intravenous Immunoglobulin, Pharmacology and Monitoring
Intravenous immunoglobulin (IVIG) contains the pooled immunoglobulin G (IgG) immunoglobulins from the plasma of approximately a ... 3] There are now multiple alternative IVIG preparations available for intravenous administration that have been approved by the ... Which intravenous immunoglobulin (IVIG) preparations are marketed in the US?. How is the liquid intravenous immunoglobulin ( ... What are less common adverse effects of intravenous immunoglobulin (IVIG)?. What is the efficacy of high-dose intravenous ...
https://www.medscape.com/answers/210367-32886/what-are-the-off-label-uses-of-intravenous-immunoglobulin-ivig-in-obstetrics
Provenge (Sipuleucel-T Suspension for Intravenous Infusion): Uses, Dosage, Side Effects, Interactions, WarningProvenge (Sipuleucel-T Suspension for Intravenous Infusion): Uses, Dosage, Side Effects, Interactions, Warning
Sipuleucel-T Suspension for Intravenous Infusion) may treat, side effects, dosage, drug interactions, warnings, patient ... Administration Steps. *Remove the infusion bag from the insulated polyurethane container and inspect the bag for signs of ... For intravenous use only.. Dose. Each dose of PROVENGE contains a minimum of 50 million autologous CD54 cells activated with ... See DOSAGE AND ADMINISTRATION]. Thromboembolic Events. Thromboembolic events, including deep venous thrombosis and pulmonary ...
https://www.rxlist.com/provenge-drug.htm
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex...Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex...
Effect of perioperative intravenous lidocaine administration on pain, opioid consumption, and quality of life after complex ...
https://snacc.org/document/effect-of-perioperative-intravenous-lidocaine-administration-on-pain-opioid-consumption-and-quality-of-life-after-complex-spine-surgery/
Intravenous administration of allogeneic Wharton jelly-derived mesenchymal stem cells for treatment of dogs with congestive...
Intravenous administration of allogeneic Wharton jelly-derived mesenchymal stem cells for treatment of dogs with congestive ... Intravenous administration of allogeneic Wharton jelly-derived mesenchymal stem cells for treatment of dogs with congestive ... Intravenous administration of allogeneic Wharton jelly-derived mesenchymal stem cells for treatment of dogs with congestive ...
https://profiles.umassmed.edu/display/26644233
A randomised, double-blind, placebo-controlled trial to compare the early administration of intravenous haloperidol versus...A randomised, double-blind, placebo-controlled trial to compare the early administration of intravenous haloperidol versus...
A randomised, double-blind, placebo-controlled trial to compare the early administration of intravenous haloperidol versus ... placebo-controlled trial to compare the early administration of intravenous haloperidol versus placebo in the prevention and ...
http://wrap.warwick.ac.uk/106022/
Intravenous Immunoglobulins (IVIGs) - Lupus Erythromatosus A TO Z - Lupus Central StationIntravenous Immunoglobulins (IVIGs) - Lupus Erythromatosus A TO Z - Lupus Central Station
Administration: Intravenously. The dose is 400 mg/kg for 5 days. The nurse must work closely with the prescribing physician to ... Intravenous Immunoglobulins (IVIGs). Intravenous Immunoglobulins (IVIGs) may be used to control SLE with organ involvement or ... See Patient Information Sheet on Intravenous Immunoglobulins (IVIGs). Source: National Institutes of Health, U.S.Dept of Health ... https://theodora.com/lupus_central_station/intravenous_immunoglobulins_ivigs.html Copyright © 1995-2021 Photius Coutsoukis (All ...
https://theodora.com/lupus_central_station/intravenous_immunoglobulins_ivigs.html
Safety, Efficacy, and Pharmacokinetic Studies to Support Marketing of Immune Globulin Intravenous (Human) as Replacement...Safety, Efficacy, and Pharmacokinetic Studies to Support Marketing of Immune Globulin Intravenous (Human) as Replacement...
... and Pharmacokinetic Studies to Support Marketing of Immune Globulin Intravenous (Human) as Replacement Therapy for Primary ... Food and Drug Administration. 5630 Fishers Lane, Rm 1061. Rockville, MD 20852 ... Safety, Efficacy, and Pharmacokinetic Studies to Support Marketing of Immune Globulin Intravenous (Human) as Replacement ... Safety, Efficacy, and Pharmacokinetic Studies to Support Marketing of Immune Globulin Intravenous (Human) as Replacement ...
https://www.fda.gov/regulatory-information/search-fda-guidance-documents/safety-efficacy-and-pharmacokinetic-studies-support-marketing-immune-globulin-intravenous-human
Cyclosporine metabolism and pharmacokinetics following intravenous and oral administration in the dog - Fingerprint -...
Dive into the research topics of Cyclosporine metabolism and pharmacokinetics following intravenous and oral administration in ... Cyclosporine metabolism and pharmacokinetics following intravenous and oral administration in the dog. ...
https://www.scholars.northwestern.edu/en/publications/cyclosporine-metabolism-and-pharmacokinetics-following-intravenou/fingerprints/
Intravenous Rehydration | Definition and Patient EducationIntravenous Rehydration | Definition and Patient Education
Intravenous (IV) rehydration is a procedure used to treat moderate to severe cases of dehydration. Learn what this procedure ... Intravenous (IV) medications are given into your vein. Learn about the types of IV administration, their uses, and the risks. ... What is intravenous rehydration?. Your doctor, or your childs doctor, may prescribe intravenous (IV) rehydration to treat ... Intravenous hydration. (2012, May 9). shs-manual.ucsc.edu/policy/intravenous-hydration. ...
https://www.healthline.com/health/intravenous-rehydration
Doxil (Doxorubicin Liposomal) Intravenous: Uses, Side Effects, DosageDoxil (Doxorubicin Liposomal) Intravenous: Uses, Side Effects, Dosage
Doxorubicin liposome is an intravenous chemotherapy used to treat ovarian cancer, AIDS-related Kaposis sarcoma, and multiple ... Following its administration, your urine, tears, and sweat might be reddish-orange. This is a normal effect of the drug and ... Doxil (Doxorubicin Liposomal) - Intravenous Generic Name: doxorubicin liposome (dox-oh-ROO-bi-sin hye-droe-KLOR-ide LYE-poh- ... Doxil (doxorubicin liposome) infusion is an intravenous (IV) chemotherapy medication used to treat different types of cancer, ...
https://www.verywellhealth.com/doxil-doxorubicin-liposomal-intravenous-5969528
Table 2 - Sphingomonas paucimobilis Bloodstream Infections Associated with Contaminated Intravenous Fentanyl - Volume 15,...
All infections (except in patient 1) developed after administration of intravenous fentanyl compounded at an out-of-state ... Intravenous fentanyl in 0.9% sodium chloride solution from a 250-mL (10 mcg/mL) bag prepared at compounding pharmacy A.. ‡ ... Sphingomonas paucimobilis Bloodstream Infections Associated with Contaminated Intravenous Fentanyl1 Lisa L. Maragakis. , ... Date(s) of fentanyl administration†. Date(s) of infection. Treatment. Outcome. PFGE strain‡. ...
https://wwwnc.cdc.gov/eid/article/15/1/08-1054-t2
Light-protective Yuria-Pharm system for intravenous administration - YURiA-PHARMLight-protective Yuria-Pharm system for intravenous administration - YURiA-PHARM
Light-protective Yuria-Pharm system for intravenous administration Yuria-Pharm light protection system has a special design of ... 21G injection needle (0.8 x 38 mm) for intravenous access;. *a patch of 3 tapes to fix the needle and tube system to the ... as well as use the system for the administration of drugs that require protection from the sun; ...
https://www.uf.ua/en/product/light-protective-yuria-pharm-system-for-intravenous-administration/
A seven-day study of the pharmacokinetics of intravenous levetiracetam in neonates: marked changes in pharmacokinetics occur...A seven-day study of the pharmacokinetics of intravenous levetiracetam in neonates: marked changes in pharmacokinetics occur...
Piracetam / administration & dosage * Piracetam / analogs & derivatives* * Piracetam / pharmacokinetics * Seizures / drug ... Methods: Eighteen term neonates with seizures persisting after 20 mg/kg of phenobarbital received intravenous LEV for 1 wk. LEV ... A seven-day study of the pharmacokinetics of intravenous levetiracetam in neonates: marked changes in pharmacokinetics occur ...
https://pubmed.ncbi.nlm.nih.gov/22495532/?dopt=Abstract
Antibiotic concentration in human wound fluid after intravenous administration<...Antibiotic concentration in human wound fluid after intravenous administration<...
Antibiotic concentration in human wound fluid after intravenous administration. D. H. Bagley, J. Mac Lowry, R. M. Beazley, C. ... Antibiotic concentration in human wound fluid after intravenous administration. / Bagley, D. H.; Mac Lowry, J.; Beazley, R. M. ... Antibiotic concentration in human wound fluid after intravenous administration. In: Unknown Journal. 1978 ; Vol. 188, No. 2. pp ... Antibiotic concentration in human wound fluid after intravenous administration. Unknown Journal. 1978;188(2):202-208. doi: ...
https://ohsu.pure.elsevier.com/en/publications/antibiotic-concentration-in-human-wound-fluid-after-intravenous-a-2
InfusionDoseIntramuscularInjectionsInjectionVersusAssigned to receive intravenousPharmacokinetics of intravenousAvailable for intravenousPatientsRoutesSodium chlorideMesenchymal stemAntibioticsFluidsGammaglobulinFerricPharmacologyMedication administrationRoute of administratRatsAntibioticIVIgPseudomonasSalineImmunoglobulinEfficacyChemotherapyTreatmentClinicalTherapyDosesIntratrachealSyringesVeinDilutionFood and Drug AdminAnesthesiaBenzodiazepinesSepsisPeak plasma concentrationInfectionPhaseTumorHextendDrug AdministrationCardiac
Infusion11
  • A subcutaneous formulation of trastuzumab has been developed, offering potential improvements in patient convenience and resource use compared with the standard intravenous infusion of the drug. (thelancet.com)
  • Provenge (sipuleucel-T) Suspension for Intravenous Infusion is a prescription medicine used to treat the symptoms of Prostate Cancer. (rxlist.com)
  • PROVENGE (sipuleucel-T) is an autologous cellular immunotherapy available as a suspension for intravenous infusion. (rxlist.com)
  • Selexipag for intravenous administration, twice daily as an infusion over 87 min. (clinicaltrials.gov)
  • After identical single intravenous or intramuscular doses of aztreonam for injection, the serum concentrations of aztreonam are comparable at 1 hour (1.5 hours from start of intravenous infusion) with similar slopes of serum concentrations thereafter. (nih.gov)
  • If the method of administration is through continuous infusion, the rate of infusion must be confirmed with another nurse (Joanna Briggs Institute, 2005). (phdessay.com)
  • The Phase 1a part of the study is a dose-escalation and dose-optimization phase investigating NG-641 administration by intravenous (IV) infusion in a range of tumour types. (clinicaltrials.gov)
  • Aciclovir/Herperax in Kenya is administered by intravenous infusion as the sodium salt over 1 hour. (epharmacyke.com)
  • HEXTEND is administered by intravenous infusion only. (pfizermedicalinformation.com)
  • The recommended dosing regimen in adult and pediatric patients, one month of age or older weighing 5 kg or greater, with PNH and aHUS consists of a loading dose followed by maintenance dosing, administered by intravenous infusion. (centerwatch.com)
  • Adjust vaccinations to accommodate concomitant corticosteroid administration prior to and following onasemnogene abeparvovec infusion. (medscape.com)
Dose18
  • In both experiments acute pretreatment with GHB significantly and dose dependently reduced cocaine self-administration. (erowid.org)
  • PA401 has been tested in murine models of lung inflammation induced by lipopolysaccharide (LPS) showing strong dose-dependent neutrophil reduction in bronchoalveolar lavage fluid (BALF) after intravenous (IV) and subcutaneous (SC) administration. (ersjournals.com)
  • 12) administration of a single dose (0.2 mg/kg). (avma.org)
  • The primary objective of this study is to assess whether it is safe for patients with PAH to temporarily change from selexipag tablets (Uptravi®) to selexipag given directly into a vein (intravenous selexipag), and then switching back to the initial oral dose of selexipag. (clinicaltrials.gov)
  • For Pseudomonas aeruginosa , a single 2 g intravenous dose produces serum levels that exceed the MIC 90 for approximately 4 to 6 hours. (nih.gov)
  • The serum half-life of aztreonam averaged 1.7 hours (1.5 to 2) in subjects with normal renal function, independent of the dose and route of administration. (nih.gov)
  • In their regimen, the intravenous dose of atropine was increased stepwise until vomiting was controlled, so the final dose administered varied between patients. (bmj.com)
  • An increase in heart rate of about 35 beats/minute (which is usually not noticed by the recipient) within 3-5 minutes of an I.V. dose, and a maximal increase in heart rate of about 35-45 beats/minute with I.M. or autoinjector administration, respectively, within about 35-45 minutes (the longer being with I.M. injection). (cdc.gov)
  • The physician reviewed the patient's medication administration record and determined that she received one dose of levofloxacin. (ahrq.gov)
  • For herpes simplex infections in the immunocompromised, and for severe initial genital herpes, or varicella-zoster infections in immunocompetent patients, the dose by the intravenous route is 5 mg/kg given every 8 hours, and recommended periods of treatment range from 5 to 7 days. (epharmacyke.com)
  • In children, the 8-hourly intravenous dose is best calculated by body-surface using 250 mg/m 2 for herpes simplex and varicella-zoster infections in immunocompetent patients and 500 mg/m 2 for herpes simplex encephalitis and varicella-zoster infection in the immunocompromised. (epharmacyke.com)
  • In groups 1 and 2, each bird received a single dose of ART at 2 mg/kg by oral (PO) and intravenous (IV) administrations, respectively. (avensonline.org)
  • The recommended dose for acute bovine mastitis is 2.2 mg/kg (1.0 mg/lb: 2 mL per 100 lbs) ofbodyweight given once by intravenous administration. (entirelypetspharmacy.com)
  • Starting 2 weeks after the loading dose administration, begin maintenance doses once every 4 or 8 weeks (q4w or q8w), based on body weight. (centerwatch.com)
  • to investigate dental patients undergoing sedation using a mean dose of 0.6 mg/kg intravenous midazolam and the adverse events of sedation in patients with ID. (bvsalud.org)
  • This study analyzed the records of 163 dental patients with ID aged between 2 and 76 years who had undergone conscious intravenous sedation (CIV) using a mean dose of 0.61 mg/kg of midazolam at Araçatuba Dental School, São Paulo State University, Brazil. (bvsalud.org)
  • The recommended dose of t-PA for acute ischemic stroke is 0.9 mg/kg (maximum 90 mg) infused over 60 minutes with 10% of the total dose administered as an initial intravenous bolus over 1 minute (see t-PA dosing chart). (medscape.com)
  • 8. Monitor dose administration carefully as total dose is weight-based (0.9 mg/kg or a maximum of 90 mg), so not all the liquid in the vial will be administered. (medscape.com)
Intramuscular5
  • Following constitution, the product is for intramuscular or intravenous use. (nih.gov)
  • The purpose of this study was to determine intravenous (IV), intramuscular (IM) and oral (PO) FM PK in mature swine. (biomedcentral.com)
  • Flunixin-meglumine (FM) is approved in the US as an intramuscular (IM) injection in swine, and is available for intravenous (IV) and oral (PO) administration in other species [ 11 ]. (biomedcentral.com)
  • All five trials are assessing intramuscular (IM) administration, with ACTIV-2 evaluating both IM and intravenous administration routes. (cision.com)
  • Treatment may be given by intravenous or intramuscular injection and repeatedfor up to five days. (entirelypetspharmacy.com)
Injections1
  • Single 3-minute intravenous injections of the same doses resulted in serum levels of 58 mcg/mL, 125 mcg/mL, and 242 mcg/mL at 5 minutes following completion of injection. (nih.gov)
Injection5
  • 12 healthy male volunteers received an intravenous injection of hydroxy-gli (1.5 mg) or placebo in a single blind, randomised, cross-over study. (nih.gov)
  • This is the number of participants with at least one clinically significant reaction at the injection site (e.g., erythema/redness, tenderness, swelling, induration, hemorrhage at the injection site) occurring on the days of intravenous (iv) selexipag injection. (clinicaltrials.gov)
  • Diabetes was induced by the intravenous injection of 60 mg/kg STZ. (elis.sk)
  • HEXTEND ® (6% Hetastarch in Lactated Electrolyte Injection) is a sterile, nonpyrogenic solution for intravenous administration. (pfizermedicalinformation.com)
  • Ultomiris is supplied as an injection for intravenous administration. (centerwatch.com)
Versus2
  • Intravenous versus Non-Intravenous Benzodiazepines for the Abortion of Seizures: A Systematic Review and Meta-analysis of Randomized Controlled Trials. (epmonthly.com)
  • There is a lack of evidence to guide emergency physicians regarding selection of patients for oral versus intravenous antibiotic therapy. (medecinedurgence.fr)
Assigned to receive intravenous1
  • 299 patients were randomly assigned to receive intravenous trastuzumab and 297 to receive subcutaneous trastuzumab. (thelancet.com)
Pharmacokinetics of intravenous1
  • The influence of surgery and anesthesia on the pharmacokinetics of intravenous tramadol in dogs was investigated. (scialert.net)
Available for intravenous1
  • [ 3 ] There are now multiple alternative IVIG preparations available for intravenous administration that have been approved by the Food and Drug Administration (FDA) for the treatment of primary humoral immunodeficiencies and chronic immune thrombocytopenic purpura. (medscape.com)
Patients19
  • Doctors should cease using Octagam intravenous immunoglobulin solutions immediately, and switch their patients to the most appropriate alternative treatment. (tga.gov.au)
  • Patients and health care providers should report any adverse events that have occurred following administration of Octagam intravenous immunoglobulin solution to the TGA via the Adverse Medicine Events Line (1300 134 237), online via ' Report a problem with a medicine ', or using the 'Blue Card' Prepaid Reporting Form . (tga.gov.au)
  • On December 23, 2014, the New York State Department of Health (NYSDOH) was notified of adverse health events in two patients who had been inadvertently administered nonsterile, simulation 0.9% sodium chloride intravenous (IV) fluids at an urgent care facility. (cdc.gov)
  • NYSDOH issued a state health advisory and posted a report on CDC's Epidemic Information Exchange (Epi-X) to inform public health personnel and medical providers of the potential for inadvertent administration of this product to patients. (cdc.gov)
  • Simultaneously, the Food and Drug Administration issued an alert, warning health care professionals not to use any Wallcur simulation IV products in human or animal patients. (cdc.gov)
  • Ten health care facilities from nine states might have administered the simulation 0.9% saline product to 45 patients (i.e., simulation saline was either administered or reported to be in the facility at the time of saline administration), although the total number of patients nationwide receiving the simulation product is unknown. (cdc.gov)
  • We compared the pharmacokinetic profile, efficacy, and safety of the subcutaneous and intravenous formulations in patients with HER2-positive early breast cancer. (thelancet.com)
  • The target population for intravenous selexipag includes those PAH patients who are hospitalized and are unable to swallow tablets of Uptravi. (clinicaltrials.gov)
  • Intravenous ferric carboxymaltose is now a potential option for treating patients with iron deficiency anaemia in the community. (bpac.org.nz)
  • Intravenous iron is the preferred form of iron supplementation for some patients with co-morbidities such as chronic kidney disease, symptomatic heart failure or inflammatory bowel disease. (bpac.org.nz)
  • Intravenous iron supplementation is regarded as the first-line treatment for iron deficiency anaemia in some patients with inflammatory bowel disease, chronic kidney disease or heart failure. (bpac.org.nz)
  • these patients have a worse prognosis if they also have iron deficiency, therefore guidelines recommend intravenous iron to alleviate symptoms, improve exercise capacity and quality of life. (bpac.org.nz)
  • Intravenous iron treatment is appropriate for patients who initially have severe anaemia as it produces a quicker improvement in the first weeks of treatment than oral iron supplementation. (bpac.org.nz)
  • Healthcare providers who see cases of Pseudomonas infection in patients with intravenous catheters are urged to determine if their patients received the recalled heparin/saline flush solution. (cdc.gov)
  • Intravenous sedation for dental patients with intellectual disability. (bvsalud.org)
  • 10. Fukuta O, Braham RL, Yanase H, Kurosu K. The sedative effects of intranasal midazolam administration in the dental treatment of patients with mental disabilities. (bvsalud.org)
  • Within this group, epilepsy is refractory in up to 40 % of patients, who have shown para el control de síntomas refractarios en a decrease in the frequency of seizures with the concomitant use of cannabidiol and conventional antiepileptics, with mild síndromes convulsivos side effects such as diarrhea and drowsiness. (bvsalud.org)
  • A comprehensive overview of medical AI devices approved by the US Food and Drug Administration sheds new light on limitations of evaluation that can mask vulnerabilities of devices when they are deployed on patients. (cdc.gov)
  • ABSTRACT Objective: To evaluate the effect of training on intravenous medication administration in pediatric patients on nursing staff 's learning and response. (bvsalud.org)
Routes3
  • No adverse effects were observed with flunixin meglumine administration for all routes. (biomedcentral.com)
  • Do Intravenous First-Line Benzodiazepines Terminate Seizures Faster Than Non-Intravenous Routes? (epmonthly.com)
  • Preferred routes of administration of atropine. (cdc.gov)
Sodium chloride1
  • Intravenous fentanyl in 0.9% sodium chloride solution from a 250-mL (10 mcg/mL) bag prepared at compounding pharmacy A. ‡Strain A is the outbreak strain that was indistinguishable by PFGE from the fentanyl isolates. (cdc.gov)
Mesenchymal stem2
  • Intravenous administration of allogeneic Wharton jelly-derived mesenchymal stem cells for treatment of dogs with congestive heart failure secondary to myxomatous mitral valve disease. (umassmed.edu)
  • Classical monocyte-derived macrophages as therapeutic targets of umbilical cord mesenchymal stem cells: comparison of intratracheal and intravenous administration in a mouse model of pulmonary fibrosis. (bvsalud.org)
Antibiotics3
  • The patient was intubated, and intravenous antibiotics, norepinephrine, and hydrocortisone were initiated to treat presumed septic shock. (ajmc.com)
  • The patient improved with antibiotics and intravenous gammaglobulin therapy. (medscape.com)
  • 59 (70.2) had had some experience with intravenous antibiotics administration. (bvsalud.org)
Fluids1
  • Photographed inside the Yirgalem prison, located in the Southern Nation and Nationality Peoples Region of Ethiopia, this image was captured during an Ethiopian Field Epidemiology Training Program (FETP) tick-borne relapsing fever (TBRF) outbreak investigation, and depicted a number of prisoners receiving treatment for TBRF, which included the administration of intravenous fluids. (cdc.gov)
Gammaglobulin1
  • Also, a liquid, pasteurized, 10% concentrated intravenous gammaglobulin preparation is as effective as a 5% concentrated preparation, making the concentrated versions more convenient to administer. (medscape.com)
Ferric1
  • intravenous Ferric carbo Exxon Maltose is indicated for iron deficiency when oral preparations are ineffective or not tolerated. (voices.com)
Pharmacology2
  • Teaching correct method of intravenous drug administration and the communication skills about drug therapy in Pharmacology practical classes can help in minimizing the errors in drug administration and improving the patient compliance and adherence to the therapy. (who.int)
  • Objectives of this study were teaching module on intravenous drug administration and communication skills to undergraduate students in Pharmacology and to evaluate the perceptions of students and teachers towards the new teaching module.Methods: Correct methods of intravenous drug administration were demonstrated in practical classes. (who.int)
Medication administration1
  • Measures included cardiac monitoring, intubation, intravenous line placement, and cardiac resuscitation medication administration. (cdc.gov)
Route of administrat1
  • route of administration, and type of operant response required. (erowid.org)
Rats5
  • In the present study, two sets of experiments were performed to investigate the effects of acute pretreatment with GHB on intravenous cocaine self-administration in rats. (erowid.org)
  • We therefore performed a systematic study to identify the permeation properties of geraniol across intestinal cells, and its pharmacokinetics and bioavailability after intravenous and oral administration to rats. (frontiersin.org)
  • After intravenous administration of geraniol to rats (50 mg/kg), its concentration in whole blood (detected via HPLC) decreased following an apparent pseudo-first order kinetics with a half-life of 12.5 ± 1.5 min. (frontiersin.org)
  • Following emulsified oral administration, geraniol amounts in the cerebrospinal fluid of rats ranged between 0.72 ± 0.08 μg/mL and 2.6 ± 0.2 μg/mL within 60 min. (frontiersin.org)
  • Conjugated or free geraniol metabolites were identified in the urine of rats after oral administration of the monoterpene (800 mg/Kg for 20 days). (frontiersin.org)
Antibiotic1
  • Oral antibiotic treatment failure was defined as any of the following after a minimum of 48 hours of oral therapy due to worsening infection: 1) hospitalization, 2) change in class of oral antibiotic, or 3) switch to intravenous therapy. (medecinedurgence.fr)
IVIg3
  • The TGA has become aware of reports of a markedly increased incidence of serious adverse reactions associated with Octagam, an intravenous immunoglobulin (IVIg) preparation, manufactured by Octapharma in Europe. (tga.gov.au)
  • Intravenous immunoglobulin (IVIG) contains the pooled immunoglobulin G (IgG) immunoglobulins from the plasma of approximately a thousand or more blood donors. (medscape.com)
  • One of biggest advances with IVIG in recent years has been the use of sorbitol-based formulations as opposed to sucrose-based formulations which allow for IV administration with less reactions. (medscape.com)
Pseudomonas1
  • A large outbreak of Pseudomonas infections was caused by exposure to a contaminated heparin/saline flush syringe that is used in the maintenance of intravenous catheters. (cdc.gov)
Saline2
  • it is intended for use by medical trainees practicing IV administration of saline on mannequins or other training devices. (cdc.gov)
  • In the present study we have compared PA401 activity after IV and intratracheal (IT) administration in the same model, using saline exposed mice as control. (ersjournals.com)
Immunoglobulin5
  • The Therapeutic Goods Administration (TGA) advises that Octapharma Australia Pty Ltd has agreed to a precautionary voluntary recall of all batches of Octagam intravenous immunoglobulin solutions from the Australian market, due to safety concerns regarding an increased incidence of thromboembolic complications associated with the use of this product in Europe and the USA. (tga.gov.au)
  • Although thromboembolic events are a known rare adverse event associated with the administration of all intravenous immunoglobulin preparations, as described in the prescribing information for these products, there has recently been a steady accumulation of such events reported following administration of Octagam in Europe and the USA, with a marked increase in incidence noted during the last few months of 2010. (tga.gov.au)
  • The TGA has considered the available evidence related to the safety of this product, and with the cooperation of Octapharma Australia Pty Ltd, has agreed that as a precautionary measure, a voluntary recall of all batches of Octagam intravenous immunoglobulin solutions should be instituted in Australia, until the cause of the problem has been identified and appropriate corrective actions have been taken by the manufacturer. (tga.gov.au)
  • As a result of this decision, all stock of Octagam intravenous immunoglobulin solutions in Australia will be recalled immediately. (tga.gov.au)
  • Adequate supplies of alternative intravenous immunoglobulin solution products are available for clinical use in Australia, and it is not anticipated that this recall will lead to any shortage of supply in the foreseeable future. (tga.gov.au)
Efficacy2
  • We, FDA, are providing you, Investigational New Drug Application (IND) sponsors and Biologics License Application (BLA) applicants, recommendations for testing the safety and efficacy of Immune Globulin Intravenous (Human) (IGIV) products as replacement therapy in primary humoral immunodeficiency. (fda.gov)
  • To assess the efficacy of a new regimen of intravenous atropine treatment for infantile hypertrophic pyloric stenosis (IHPS) with special reference to regression of pyloric hypertrophy. (bmj.com)
Chemotherapy1
  • The Current Procedural Terminology (CPT) code range for Chemotherapy Administration and Other Highly Complex Drug or Highly Complex Biologic Agent Administration 96401-96417 is a medical code set maintained by the American Medical Association. (aapc.com)
Treatment10
  • After screening (Visit 1), each subject will participate in the following consecutive treatment periods: Period 1(treatment with oral selexipag at Visit 2/Day 1), Period 2 (treatment with intravenous selexipag at Visit 2/ Day 2 and Day 3), Period 3 (treatment with oral selexipag starting in the evening of Visit 2/Day 3 and ending 7 to 11 days later at Visit 3). (clinicaltrials.gov)
  • intravenous iron treatment is preferred as oral iron supplementation does not supply sufficient iron to the bone marrow to support erythropoiesis. (bpac.org.nz)
  • Of the 19 infants, 17 (89%) ceased projectile vomiting after treatment with intravenous (median seven days) and subsequent oral (median 44 days) atropine administration. (bmj.com)
  • 8, 9 Nagita et al 8 have reported a high success rate using intravenous atropine treatment. (bmj.com)
  • If there is no IV access, then non-IV administration, especially IM or IN midazolam is the treatment of choice. (epmonthly.com)
  • In the mouse model, the increased number of inflammatory cells in the bronchoalveolar lavage fluid and the degree of lung fibrosis observed in BLM-treated mice were significantly reduced by MSC treatment , which tended to be more prominent with intravenous administration than intratracheal administration . (bvsalud.org)
  • However, he developed a hemorrhagic shock due to sudden splenic rupture and continued to deteriorate despite treatment with selective embolization of a branch of the splenic artery, blood transfusion, and administration of norepinephrine and adrenaline. (ajmc.com)
  • 11. Averley PA, Girdler NM, Bond S, Steen N, Steele J. A randomised controlled trial of paediatric conscious sedation for dental treatment using intravenous midazolam combined with inhaled nitrous oxide or nitrous oxide/ sevoflurane. (bvsalud.org)
  • 13. Chaushu S, Gozal D, Becker A. Intravenous sedation: an adjunct to enable orthodontic treatment for children with disabilities. (bvsalud.org)
  • Treatment consists of intravenous administration of 3 mg/kg Ipilimumab, every three weeks. (bvsalud.org)
Clinical1
  • 4 Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Health Science Centre, Xi'an Jiaotong University, China. (who.int)
Therapy2
  • Therefore, the nasal route for administration of epinephrine appears to be an acceptable alternate method of drug delivery during CPR and compares favorably with standard IV therapy in the canine model. (druglib.com)
  • For these reasons, this intravenous anaesthetic is specifically useful for short surgical operations, such as oral surgery, gynaecological investigation, genitourinary procedures, and electroconvulsive therapy. (pharmacy180.com)
Doses1
  • 1 to 2 mLper 100 lbs) of bodyweight given by slow intravenous administration either once a day as a single doseor divided into two doses administered at 12 hour intervals for up to 3 days. (entirelypetspharmacy.com)
Intratracheal3
  • After establishing a pulmonary fibrosis model via the intratracheal administration of bleomycin (BLM) to 8-week-old mice , MSCs derived from human umbilical cords were administered intravenously or intratracheally on day 10 and the lungs were immunologically analyzed on days 14 and 21. (bvsalud.org)
  • Among M2 MoMs, M2 MoMs derived from Ly6C+ monocytes were most effectively regulated by the intravenous administration , not intratracheal administration , of MSCs. (bvsalud.org)
  • Intravenous rather than intratracheal administration of MSCs may ameliorate pulmonary fibrosis by inhibiting monocyte differentiation into M2 macrophages . (bvsalud.org)
Syringes1
  • Reportedly, the prepared syringes were not tested for the presence of bacteria as recommended by the Good Manufacturing Practices established by the Food and Drug Administration (FDA). (cdc.gov)
Vein1
  • Intravenous - or within the vein - is a term commonly used in medicine. (completeanatomy.cn)
Dilution1
  • The molecule consists of an iron hydroxide core collated in a carbohydrate shell after the dilution and intravenous administration. (voices.com)
Food and Drug Admin6
  • Healthcare providers may prescribe Doxil for off-label uses, meaning for conditions not specifically indicated by the Food and Drug Administration (FDA). (verywellhealth.com)
  • In 2014, the U.S. Food and Drug Administration (FDA) approved the use of a medicine called naloxone (brand name Narcan) to reverse the effects of a heroin overdose. (medlineplus.gov)
  • The value of the extended agreement is $205m and is contingent on AZD7442 receiving Food and Drug Administration Emergency Use Authorisation in post-exposure prophylaxis - the ability to prevent COVID-19 in people who have confirmed exposure to the SARS-CoV-2 virus. (cision.com)
  • To help practitioners weigh the risks and benefits of drug exposure during pregnancy, the United States Food and Drug Administration (FDA) in 1979 devised a categorization scheme to communicate the safety of medications in pregnancy in terms of effects on the fetus ( Table ). (ahrq.gov)
  • If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly by visiting www.fda.gov/medwatch or by calling (800)-332-1088 . (pfizermedicalinformation.com)
  • There are no Food and Drug Administration (FDA)-approved treatments for monkeypox. (cdc.gov)
Anesthesia2
  • The current study compared the long-term biochemical recurrence of prostate cancer after robot-assisted laparoscopic radical prostatectomy (RALP) in terms of selection of anesthetic agent between total intravenous anesthesia (TIVA) with propofol/remifentanil and volatile anesthetics (VA) with sevoflurane or desflurane/remifentanil. (medsci.org)
  • Propofol has been reported to exhibit positive immunomodulatory effects [ 3 - 5 ], and better survival has been reported after cancer surgery with propofol-based total intravenous anesthesia (TIVA) compared to volatile anesthesia (VA) [ 6 - 9 ]. (medsci.org)
Benzodiazepines1
  • While the intravenous (IV) delivery of benzodiazepines (BZD) is the most direct and reliable route, non-IV administration of BZDs may be more effective due to more rapid administration. (epmonthly.com)
Sepsis1
  • Held MR , Begier EM , Beardsley DS , Browne FA , Martinello RA , Baltimore RS , Life-threatening sepsis caused by Burkholderia cepacia from contaminated intravenous flush solutions prepared by a compounding pharmacy in another state. (cdc.gov)
Peak plasma concentration2
  • A mean peak plasma concentration (C MAX ) for IM and PO administration was 3748 ng/ml (range: 2749-6004 ng/ml) and 946 ng/ml (range: 554-1593 ng/ml), respectively. (biomedcentral.com)
  • TA reaches peak plasma concentration immediately after intravenous administration A meta-analysis evaluated the use of tranexamic acid after vaginal delivery for prevention of primary PPH. (centerwatch.com)
Infection1
  • Sunenshine RH , Tan ET , Terashita DM , Jensen BJ , Kacica MA , Sickbert-Bennett EE , A multistate outbreak of Serratia marcescens bloodstream infection associated with contaminated intravenous magnesium sulfate from a compounding pharmacy. (cdc.gov)
Phase2
  • The (+) and (-) RBZ enantiomeric forms were recovered in plasma after iv and sc administration of the racemic RBZ formulation, using a chiral phase based HPLC method. (uab.cat)
  • Phase 2: self-administration questionnaire was used to investigate the surgeons' perception. (who.int)
Tumor2
  • Intravenous administration of PMB-DHMEQ reduced the tumor volume and liver metastasis compared to untreated or CMC-DHMEQ-treated mice. (elsevier.com)
  • El Ipilimumab es un anticuerpo humano monoclonal que interferiría en la interacción entre CTLA-4 y su ligando (B7) en la célula presentadora de antígeno, causando un bloqueo de su función inmunomoduladora, aumentando el número y la actividad de linfocitos T quienes atacarían el tumor. (bvsalud.org)
Hextend2
  • To determine if there were significant differences between the tibial intraosseous (TIO) and intravenous (IV) administration of Hextend relative to time and in hemodynamics in a hypovolemic model. (wmpllc.org)
  • Based upon the findings of this study, the TIO route might be considered the first choice for rapid vascular access and the administration of Hextend. (wmpllc.org)
Drug Administration3
  • Application of aseptic technique is essential in the process of drug administration through the intravenous route. (phdessay.com)
  • After drug administration, the patient must now be watched closely for adverse reaction to the drug. (phdessay.com)
  • Therefore, the objective of this study was to determine if intranasal administration of epinephrine during CPR would provide an alternate route of drug administration that is readily accessible and requires no special technical skills. (druglib.com)
Cardiac1
  • Effects of intraosseous tibial vs. intravenous vasopressin in a hypovolemic cardiac arrest model. (wmpllc.org)
Intravenous Rehydration | Definition and Patient Education
Intravenous Rehydration | Definition and Patient Education (healthline.com)
Frontiers | Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic...
Frontiers | Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic... (frontiersin.org)
Intravenous Immunoglobulins (IVIGs) - Lupus Erythromatosus A TO Z - Lupus Central Station
Intravenous Immunoglobulins (IVIGs) - Lupus Erythromatosus A TO Z - Lupus Central Station (theodora.com)
DailyMed - LINEZOLID- linezolid injection, solution
DailyMed - LINEZOLID- linezolid injection, solution (dailymed.nlm.nih.gov)
These highlights do not include all the information needed to use CEFAZOLIN FOR INJECTION safely and effectively. See full...
These highlights do not include all the information needed to use CEFAZOLIN FOR INJECTION safely and effectively. See full... (dailymed.nlm.nih.gov)
Intravenous tPA for Stroke: Putting the Controversy to Rest
Intravenous tPA for Stroke: Putting the Controversy to Rest (medscape.com)
A Phase 3 Randomized, Open-label, Multicenter Study of Isatuximab (SAR650984) in Combination With Lenalidomide and...
A Phase 3 Randomized, Open-label, Multicenter Study of Isatuximab (SAR650984) in Combination With Lenalidomide and... (clinicaltrials.gov)
Clinical Chemistry and Laboratory Medicine (CCLM) Volume 30 Issue 12
Clinical Chemistry and Laboratory Medicine (CCLM) Volume 30 Issue 12 (degruyter.com)
Narcan (Naloxone Hydrochloride Injection): Uses, Dosage, Side Effects, Interactions, Warning
Narcan (Naloxone Hydrochloride Injection): Uses, Dosage, Side Effects, Interactions, Warning (rxlist.com)
Notes from the Field: Adverse Events Associated with Administration of Simulation Intravenous Fluids to Patients - United...
Notes from the Field: Adverse Events Associated with Administration of Simulation Intravenous Fluids to Patients - United... (cdc.gov)
Rheumatoid Arthritis Pipeline Analysis by its Product Types, Stages Types, and By MOA - IPS Inter Press Service Business
Rheumatoid Arthritis Pipeline Analysis by its Product Types, Stages Types, and By MOA - IPS Inter Press Service Business (ipsnews.net)
Pfizer gets European OK for intravenous Revatio | The Daily Caller
Pfizer gets European OK for intravenous Revatio | The Daily Caller (dailycaller.com)
Carcinoma of the Ampulla of Vater: Practice Essentials, Pathophysiology, Epidemiology
Carcinoma of the Ampulla of Vater: Practice Essentials, Pathophysiology, Epidemiology (emedicine.medscape.com)
Anaphylaxis Treatment & Management: Approach Considerations, Initial Emergency Department Interventions, Administration of...
Anaphylaxis Treatment & Management: Approach Considerations, Initial Emergency Department Interventions, Administration of... (medscape.com)
Acute Bacterial Bone and Joint Infections in Children
Acute Bacterial Bone and Joint Infections in Children (medscape.com)
IJMS | Free Full-Text | Graphene Nanomaterials: Synthesis, Biocompatibility, and Cytotoxicity
IJMS | Free Full-Text | Graphene Nanomaterials: Synthesis, Biocompatibility, and Cytotoxicity (mdpi.com)