Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Carcinogenicity Tests: Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.Adenoma, Liver Cell: A benign epithelial tumor of the LIVER.Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.Liver Neoplasms: Tumors or cancer of the LIVER.Adenoma: A benign epithelial tumor with a glandular organization.Perfume: A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell, especially a fluid containing fragrant natural oils extracted from flowers, woods, etc., or similar synthetic oils. (Random House Unabridged Dictionary, 2d ed)Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Liver Neoplasms, Experimental: Experimentally induced tumors of the LIVER.Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Dicarboxylic AcidsXanthine Dehydrogenase: An enzyme that catalyzes the oxidation of XANTHINE in the presence of NAD+ to form URIC ACID and NADH. It acts also on a variety of other purines and aldehydes.Xanthine Oxidase: An iron-molybdenum flavoprotein containing FLAVIN-ADENINE DINUCLEOTIDE that oxidizes hypoxanthine, some other purines and pterins, and aldehydes. Deficiency of the enzyme, an autosomal recessive trait, causes xanthinuria.Xenodiagnosis: A method for diagnosing a disease in one organism by inoculating the putative causative organism in a second animal of a different species. It has been used for the detection of parasites (Trypanosoma cruzi and Trichinella spiralis) when peripheral blood smears are negative. (Segen, Current Med Talk, 1995)Allopurinol: A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.Nucleoproteins: Proteins conjugated with nucleic acids.Dioctyl Sulfosuccinic Acid: All-purpose surfactant, wetting agent, and solubilizer used in the drug, cosmetics, and food industries. It has also been used in laxatives and as cerumenolytics. It is usually administered as either the calcium, potassium, or sodium salt.Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Water Pollution: Contamination of bodies of water (such as LAKES; RIVERS; SEAS; and GROUNDWATER.)Herbicides: Pesticides used to destroy unwanted vegetation, especially various types of weeds, grasses (POACEAE), and woody plants. Some plants develop HERBICIDE RESISTANCE.Pesticides: Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.Insecticides: Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.Nigella: A plant genus of the family RANUNCULACEAE.Polyvinyl Chloride: A polyvinyl resin used extensively in the manufacture of plastics, including medical devices, tubing, and other packaging. It is also used as a rubber substitute.Water Pollution, Chemical: Adverse effect upon bodies of water (LAKES; RIVERS; seas; groundwater etc.) caused by CHEMICAL WATER POLLUTANTS.Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Water Pollution: Contamination of bodies of water (such as LAKES; RIVERS; SEAS; and GROUNDWATER.)Herbicides: Pesticides used to destroy unwanted vegetation, especially various types of weeds, grasses (POACEAE), and woody plants. Some plants develop HERBICIDE RESISTANCE.Pesticides: Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.Insecticides: Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.Water Pollution, Chemical: Adverse effect upon bodies of water (LAKES; RIVERS; seas; groundwater etc.) caused by CHEMICAL WATER POLLUTANTS.Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Regulatory Sequences, Nucleic Acid: Nucleic acid sequences involved in regulating the expression of genes.Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Spiramycin: A macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-positive aerobic pathogens, N. gonorrhoeae, and staphylococci. It is used to treat infections caused by bacteria and Toxoplasma gondii.Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Marketing: Activity involved in transfer of goods from producer to consumer or in the exchange of services.Research Report: Detailed account or statement or formal record of data resulting from empirical inquiry.Foundations: Organizations established by endowments with provision for future maintenance.Dietetics: The application of nutritional principles to regulation of the diet and feeding persons or groups of persons.Leucomycins: An antibiotic complex produced by Streptomyces kitasatoensis. The complex consists of a mixture of at least eight biologically active components, A1 and A3 to A9. Leucomycins have both antibacterial and antimycoplasmal activities.Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Journalism, Medical: The collection, writing, and editing of current interest material on topics related to biomedicine for presentation through the mass media, including newspapers, magazines, radio, or television, usually for a public audience such as health care consumers.Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.PiperazinesDirectories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Dicarboxylic AcidsIndiaFraud: Exploitation through misrepresentation of the facts or concealment of the purposes of the exploiter.Ascaris: A genus of nematodes of the superfamily ASCARIDOIDEA whose species usually inhabit the intestine.Buspirone: An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.Deodorants: Agents that remove, correct, repress, or mask undesirable ODORS. In personal hygiene, deodorants often contain astringent preparations that reduce SWEATING, referred to as ANTIPERSPIRANTS. (From Grant & Hackh's Chemical Dictionary, 5th ed)Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.CarbanilidesDiethylhexyl Phthalate: An ester of phthalic acid. It appears as a light-colored, odorless liquid and is used as a plasticizer for many resins and elastomers.Skin Absorption: Uptake of substances through the SKIN.Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Fenthion: Potent cholinesterase inhibitor used as an insecticide and acaricide.Prunus: A plant genus in the family ROSACEAE, order Rosales, subclass Rosidae. It is best known as a source of edible fruits such as apricot, plum, peach, cherry, and almond.Methyl Parathion: The methyl homolog of parathion. An effective, but highly toxic, organothiophosphate insecticide and cholinesterase inhibitor.Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Dicarboxylic AcidsHistory, 20th Century: Time period from 1901 through 2000 of the common era.Industry: Any enterprise centered on the processing, assembly, production, or marketing of a line of products, services, commodities, or merchandise, in a particular field often named after its principal product. Examples include the automobile, fishing, music, publishing, insurance, and textile industries.Tobacco Industry: The aggregate business enterprise of agriculture, manufacture, and distribution related to tobacco and tobacco-derived products.Drug Industry: That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.Commerce: The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)Food Industry: The industry concerned with processing, preparing, preserving, distributing, and serving of foods and beverages.Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Phthalic Acids: A group of compounds that has the general structure of a dicarboxylic acid-substituted benzene ring. The ortho-isomer is used in dye manufacture. (Dorland, 28th ed)Benzyl Alcohol: A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.Plasticizers: Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.Benzyl CompoundsDicarboxylic AcidsBenzyl Alcohols: Alcohols derived from the aryl radical (C6H5CH2-) and defined by C6H5CHOH. The concept includes derivatives with any substituents on the benzene ring.Benzyl Viologen: 1,1'-Bis(phenylmethyl)4,4'-bipyridinium dichloride. Oxidation-reduction indicator.Click Chemistry: Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.Hematinics: Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.Pulmonary Surfactants: Substances and drugs that lower the SURFACE TENSION of the mucoid layer lining the PULMONARY ALVEOLI.Surface-Active Agents: Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.Adipates: Derivatives of adipic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a 1,6-carboxy terminated aliphatic structure.Surface Tension: The force acting on the surface of a liquid, tending to minimize the area of the surface. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Pulmonary Surfactant-Associated Protein A: An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.Electroosmosis: The motion of a liquid through a membrane (or plug or capillary) consequent upon the application of an electric field across the membrane. (Oxford Dictionary of Biochemistry and Molecular Biology, 2001)Pulmonary Surfactant-Associated Proteins: Proteins found in the LUNG that act as PULMONARY SURFACTANTS.Poloxalene: A copolymer of polyethylene and polypropylene ether glycol. It is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.Cetrimonium Compounds: Cetyltrimethylammonium compounds that have cationic detergent, antiseptic, and disinfectant activities. They are used in pharmaceuticals, foods, and cosmetics as preservatives; on skin, mucous membranes, etc., as antiseptics or cleansers, and also as emulsifiers. These compounds are toxic when used orally due to neuromuscular blockade.Proteolipids: Protein-lipid combinations abundant in brain tissue, but also present in a wide variety of animal and plant tissues. In contrast to lipoproteins, they are insoluble in water, but soluble in a chloroform-methanol mixture. The protein moiety has a high content of hydrophobic amino acids. The associated lipids consist of a mixture of GLYCEROPHOSPHATES; CEREBROSIDES; and SULFOGLYCOSPHINGOLIPIDS; while lipoproteins contain PHOSPHOLIPIDS; CHOLESTEROL; and TRIGLYCERIDES.
(1/166) Dimethyl adipimidate: a new antisickling agent.

A new approach to the prevention of sickling in vitro by use of the bifunctional crosslinking reagent, dimethyl adipimidate, is described. Prior treatment of sickle erythrocytes with dimethyl adipimidate will inhibit sickling in completely deoxygenated erythrocytes. Treated erythrocytes do not demonstrate the potassium loss and viscosity increase that usually accompany sickling. The oxygen affinity of hemoglobin in these cells is increased independently from changes in the concentration of 2,3-diphosphoglycerate. The hemoglobin obtained from treated erythrocytes contains a high-molecular-weight component as well as additional positively charged components. The relative degree to which chemical modification and/or crosslinking is an essential part of the antisickling properties of the material is not known.  (+info)

(2/166) In vitro cytotoxicity of textile paint components linked to the "Ardystil syndrome".

The spraying of a paint formula (Acramin F system) had led to severe pulmonary disease in textile printing sprayers in Spain and Algeria (Ardystil syndrome). In order to elucidate the underlying mechanisms of the toxicity of this paint and its main polymeric components, Acramin FWR, Acramin FWN, Acrafix FHN, and Acramoll W, we have undertaken studies using a battery of different cell-types and assessing in vitro cytotoxicity by measuring LDH leakage. This study shows that, as in in vivo studies, the three polycationic paint components, Acramin FWR (a polyurea), Acramin FWN (a polyamide-amine), and Acrafix FHN (a polyamine) exhibited considerable cytotoxicity (LC50 generally below 100 microg/ml for an incubation of 20-24 h) in vitro, while Acramoll W, which is not a polycation, was almost non-toxic (in the concentration range tested). The cytotoxicity was comparable in primary cultures of rat and human type II pneumocytes and alveolar macrophages as well as in the pulmonary cell line A549 and the hepatic cell line HepG2. In human erythrocytes, the toxicity was less pronounced. We speculate that the multiple positive charges play an important role in the toxic mechanism. It is concluded that Acramin FWR and Acramin FWN have similar intrinsic toxicity and that these polymeric compounds, which have no irritant properties or systemic toxicity when given orally, exert a high, unexpected, degree of cytotoxicity.  (+info)

(3/166) Desulfovirga adipica gen. nov., sp. nov., an adipate-degrading, gram-negative, sulfate-reducing bacterium.

A novel, mesophilic, Gram-negative bacterium was isolated from an anaerobic digestor for municipal wastewater. The bacterium degraded adipate in the presence of sulfate, sulfite, thiosulfate and elemental sulfur. (E)-2-Hexenedioate accumulated transiently in the degradation of adipate. (E)-2-Hexenedioate, (E)-3-hexenedioate, pyruvate, lactate, C1-C12 straight-chain fatty acids and C2-C10 straight-chain primary alcohols were also utilized as electron donors. 3-Phenylpropionate was oxidized to benzoate. The G + C content of the DNA was 60 mol%. 16S rDNA sequence analysis revealed that the new isolate clustered with species of the genus Syntrophobacter and Desulforhabdus amnigenus. Strain TsuAS1T resembles Desulforhabdus amnigenus DSM 10338T with respect to the ability to utilize acetate as an electron donor and the inability to utilize propionate without sulfate in co-culture with Methanospirillum hungatei DSM 864. Strains TsuAS1T and DSM 10338T form a 'non-syntrophic subcluster' within the genus Syntrophobacter. Desulfovirga adipica gen. nov., sp. nov. is proposed for the newly isolated bacterium, with strain TsuAS1T (= DSM 12016T) as the type strain.  (+info)

(4/166) Characterization of a second tfd gene cluster for chlorophenol and chlorocatechol metabolism on plasmid pJP4 in Ralstonia eutropha JMP134(pJP4).

Within the 5.9-kb DNA region between the tfdR and tfdK genes on the 2,4-dichlorophenoxyacetic acid (2,4-D) catabolic plasmid pJP4 from Ralstonia eutropha JMP134, we identified five open reading frames (ORFs) with significant homology to the genes for chlorocatechol and chlorophenol metabolism (tfdCDEF and tfdB) already present elsewhere on pJP4. The five ORFs were organized and assigned as follows: tfdD(II)C(II)E(II)F(II) and tfdB(II) (in short, the tfd(II) cluster), by analogy to tfdCDEF and tfdB (the tfd(I) cluster). Primer extension analysis of mRNA isolated from 2,4-D-grown R. eutropha JMP134 identified a single transcription start site in front of the first gene of the cluster, tfdD(II), suggesting an operon-like organization for the tfd(II) genes. By expressing each ORF in Escherichia coli, we confirmed that tfdD(II) coded for a chloromuconate cycloisomerase, tfdC(II) coded for a chlorocatechol 1, 2-dioxygenase, tfdE(II) coded for a dienelactone hydrolase, tfdF(II) coded for a maleylacetate reductase, and tfdB(II) coded for a chlorophenol hydroxylase. Dot blot hybridizations of mRNA isolated from R. eutropha JMP134 showed that both tfd(I) and tfd(II) genes are transcribed upon induction with 2,4-D. Thus, the functions encoded by the tfd(II) genes seem to be redundant with respect to those of the tfd(I) cluster. One reason why the tfd(II) genes do not disappear from plasmid pJP4 might be the necessity for keeping the regulatory genes for the 2,4-D pathway expression tfdR and tfdS.  (+info)

(5/166) Genetic analysis of a gene cluster for cyclohexanol oxidation in Acinetobacter sp. Strain SE19 by in vitro transposition.

Biological oxidation of cyclic alcohols normally results in formation of the corresponding dicarboxylic acids, which are further metabolized and enter the central carbon metabolism in the cell. We isolated an Acinetobacter sp. from an industrial wastewater bioreactor that utilized cyclohexanol as a sole carbon source. A cosmid library was constructed from Acinetobacter sp. strain SE19, and oxidation of cyclohexanol to adipic acid was demonstrated in recombinant Escherichia coli carrying a SE19 DNA segment. A region that was essential for cyclohexanol oxidation was localized to a 14-kb fragment on the cosmid DNA. Several putative open reading frames (ORFs) that were expected to encode enzymes catalyzing the conversion of cyclohexanol to adipic acid were identified. Whereas one ORF showed high homology to cyclohexanone monooxygenase from Acinetobacter sp. strain NCIB 9871, most of the ORFs showed only moderate homology to proteins in GenBank. In order to assign functions of the various ORFs, in vitro transposon mutagenesis was performed using the cosmid DNA as a target. A set of transposon mutants with a single insertion in each of the ORFs was screened for cyclohexanol oxidation in E. coli. Several of the transposon mutants accumulated a variety of cyclohexanol oxidation intermediates. The in vitro transposon mutagenesis technique was shown to be a powerful tool for rapidly assigning gene functions to all ORFs in the pathway.  (+info)

(6/166) Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate.

The nuclear genome of Saccharomyces cerevisiae encodes 35 members of a family of membrane proteins. Known members transport substrates and products across the inner membranes of mitochondria. We have localized two hitherto unidentified family members, Odc1p and Odc2p, to the inner membranes of mitochondria. They are isoforms with 61% sequence identity, and we have shown in reconstituted liposomes that they transport the oxodicarboxylates 2-oxoadipate and 2-oxoglutarate by a strict counter exchange mechanism. Intraliposomal adipate and glutarate and to a lesser extent malate and citrate supported [14C]oxoglutarate uptake. The expression of Odc1p, the more abundant isoform, made in the presence of nonfermentable carbon sources, is repressed by glucose. The main physiological roles of Odc1p and Odc2p are probably to supply 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol where they are used in the biosynthesis of lysine and glutamate, respectively, and in lysine catabolism.  (+info)

(7/166) Key aromatic-ring-cleaving enzyme, protocatechuate 3,4-dioxygenase, in the ecologically important marine Roseobacter lineage.

Aromatic compound degradation in six bacteria representing an ecologically important marine taxon of the alpha-proteobacteria was investigated. Initial screens suggested that isolates in the Roseobacter lineage can degrade aromatic compounds via the beta-ketoadipate pathway, a catabolic route that has been well characterized in soil microbes. Six Roseobacter isolates were screened for the presence of protocatechuate 3,4-dioxygenase, a key enzyme in the beta-ketoadipate pathway. All six isolates were capable of growth on at least three of the eight aromatic monomers presented (anthranilate, benzoate, p-hydroxybenzoate, salicylate, vanillate, ferulate, protocatechuate, and coumarate). Four of the Roseobacter group isolates had inducible protocatechuate 3, 4-dioxygenase activity in cell extracts when grown on p-hydroxybenzoate. The pcaGH genes encoding this ring cleavage enzyme were cloned and sequenced from two isolates, Sagittula stellata E-37 and isolate Y3F, and in both cases the genes could be expressed in Escherichia coli to yield dioxygenase activity. Additional genes involved in the protocatechuate branch of the beta-ketoadipate pathway (pcaC, pcaQ, and pobA) were found to cluster with pcaGH in these two isolates. Pairwise sequence analysis of the pca genes revealed greater similarity between the two Roseobacter group isolates than between genes from either Roseobacter strain and soil bacteria. A degenerate PCR primer set targeting a conserved region within PcaH successfully amplified a fragment of pcaH from two additional Roseobacter group isolates, and Southern hybridization indicated the presence of pcaH in the remaining two isolates. This evidence of protocatechuate 3, 4-dioxygenase and the beta-ketoadipate pathway was found in all six Roseobacter isolates, suggesting widespread abilities to degrade aromatic compounds in this marine lineage.  (+info)

(8/166) Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location.

In Saccharomyces cerevisiae, the genes ODC1 and ODC2 encode isoforms of the oxodicarboxylate carrier. They both transport C5-C7 oxodicarboxylates across the inner membranes of mitochondria and are members of the family of mitochondrial carrier proteins. Orthologs are encoded in the genomes of Caenorhabditis elegans and Drosophila melanogaster, and a human expressed sequence tag (EST) encodes part of a closely related protein. Information from the EST has been used to complete the human cDNA sequence. This sequence has been used to map the gene to chromosome 14q11.2 and to show that the gene is expressed in all tissues that were examined. The human protein was produced by overexpression in Escherichia coli, purified, and reconstituted into phospholipid vesicles. It has similar transport characteristics to the yeast oxodicarboxylate carrier proteins (ODCs). Both the human and yeast ODCs catalyzed the transport of the oxodicarboxylates 2-oxoadipate and 2-oxoglutarate by a counter-exchange mechanism. Adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate were also transported by the human ODC. The main differences between the human and yeast ODCs are that 2-aminoadipate is transported by the former but not by the latter, whereas malate is transported by the yeast ODCs but not by the human ortholog. In mammals, 2-oxoadipate is a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine. It is transported from the cytoplasm into mitochondria where it is converted into acetyl-CoA. Defects in human ODC are likely to be a cause of 2-oxoadipate acidemia, an inborn error of metabolism of lysine, tryptophan, and hydroxylysine.  (+info)

*  Plasticizer
Some examples are: Bis(2-ethylhexyl)adipate (DEHA) Dimethyl adipate (DMAD) Monomethyl adipate (MMAD) Dioctyl adipate (DOA) ... The wide variety of ester chemistries that are in production include sebacates, adipates, terephthalates, dibenzoates, ... Adipate-based plasticizers are used for low-temperature or resistance to ultraviolet light. ...
*  Adipate
Potassium adipate (E357) Some adipate esters are used as plasticizers, including: Bis(2-ethylhexyl) adipate Dioctyl adipate ... The anionic (HO2C(CH2)4CO2−) and dianionic (−O2C(CH2)4CO2−) forms of adipic acid are also referred to as adipate. Some adipate ... Adipates are the salts and esters of adipic acid. ...
*  Potassium adipate
... is a compound with formula K2C6H8O4. It is the potassium salt of adipic acid. It has E number "E357". Sodium ...
*  Dioctyl adipate
... (DOA) is a plasticizer. DOA is a diester of adipic acid and two equivalents of n-octanol. Its chemical formula ... DEHA is sometimes incorrectly called dioctyl adipate. Record in the GESTIS Substance Database of the Institute for Occupational ...
*  Polyethylene adipate
... (or PEA), is an aliphatic polyester formed from polyethylene glycol and adipic acid. Its CAS Number 24938- ... Turner-Jones, A.; Bunn, C. W. (1962). "The crystal structures of polyethylene adipate and polyethylene subarate". Acta ...
*  Ammonium adipate
... is a compound with formula (NH4)2(C4H8(COO)2). It is the ammonium salt of adipic acid. It is used as a food ...
*  Dimethyl adipate
... is a chemical compound used as a plasticizer, a solvent for paint stripping and resins, and a pigment ... Record in the GESTIS Substance Database of the Institute for Occupational Safety and Health "Dimethyl Adipate". chemicalland21. ...
*  Acetylated distarch adipate
... (E1422), is a starch that is treated with acetic anhydride and adipic acid anhydride to resist high ...
*  Bis(2-ethylhexyl) adipate
DEHA is sometimes called "dioctyl adipate", incorrectly. Other names include diisooctyl adipate and di(2-ethylhexyl) adipate. ... Bis(2-ethylhexyl) adipate or DEHA is a plasticizer. DEHA is an ester of 2-ethylhexanol and adipic acid. Its chemical formula is ... ADIPATE, 77, 2000, p. 149, retrieved 2008-12-20 Inchem Preamble Evaluation, 1-5-1999, retrieved 2008-12-20 Check date values in ...
*  2-Octanol
... adipate, maleate, stearate, myristate, etc.), Plasticizers (acrylates, maleates, etc.), Pesticides: Dinocap Lubricants: Zinc ...
*  Cyclopentane
Wislicenus prepared cyclopentane from cyclopentanone ("Ketopentamethen"), which is prepared by heating calcium adipate. ...
*  Pyrotechnic composition
For composite rocket propellants, dioctyl adipate, isodecyl pelargonate, and dioctyl phthalate are often used. Plasticizers can ...
*  2-Ethylhexanol
2-Ethylhexanoic acid Bis(2-ethylhexyl) adipate Padimate O Octyl salicylate "2-ethylhexanol - Compound Summary". PubChem ...
*  Methylene diphenyl diisocyanate
Typical polyols used are polyethylene adipate (a polyester) and poly(tetramethylene ether) glycol (a polyether). 4,4'-MDI is ...
*  John Kopchick
The title of his M.S. thesis was 'Catabolism of alpha-amino adipate by Pseudomonas putida p2'. He went on to attend the ...
*  Polyvinyl chloride
These are for example the antioxidant bisphenol A, the biocide benzisothiazolinone, propylene glycol/adipate polyester and ... DEHP alternatives, which are gradually replacing it, are Adipates, Butyryltrihexylcitrate (BTHC), Cyclohexane-1,2-dicarboxylic ...
*  Acidity regulator
Adipate List of food additives Sodium bicarbonate Erich Lück and Gert-Wolfhard von Rymon Lipinski "Foods, 3. Food Additives" in ...
*  Dibasic ester
... s of phthalates, adipates, and azelates with C8 - C10 alcohols have found commercial use as lubricants, spin ...
*  Diesel exhaust
... adipate". Reproductive Toxicology (Elmsford, N.Y.). 19 (4): 505-515. doi:10.1016/j.reprotox.2004.11.005. ISSN 0890-6238. PMID ...
*  Ham sausage
"GC/MS Method for the Determination of Adipate Plasticizers in Ham Sausage and Its Application to Kinetic and Penetration ...
*  Piperazine
... hydrate, piperazine adipate and piperazine citrate (used to treat ascariasis and enterobiasis) are the most common ... and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid). Piperazine is formed as a co- ...
*  Obesogen
... adipate" (free full text). Reprod. Toxicol. 19 (4): 505-515. doi:10.1016/j.reprotox.2004.11.005. PMID 15749265. Braga-Basaria M ...
*  DEHA
... may refer to: DEHA (apparel), an Italian dancewear label Bis(2-ethylhexyl) adipate, a plasticizer Diethylhydroxylamine, ...
*  Shampoo
Di-PPG-2 myreth-10 adipate is a water-dispersible emollient that forms clear solutions with surfactant systems ...
*  List of food additives
Amchur (mango powder) Ammonium acetate - preservative, acidity regulator Ammonium adipates - acidity regulator Ammonium ... Potassium acetates - preservative, acidity regulator Potassium adipate - food acid Potassium alginate - thickener, vegetable ... acidity regulator Sodium adipate - food acid Sodium alginate - thickener, vegetable gum, stabilizer, gelling agent, emulsifier ... emulsifier Acetylated distarch adipate - thickener, vegetable gum Acetylated distarch phosphate - thickener, vegetable gum ...
Diethyl adipate  Diethyl adipate
Ethyl adipate; 1,6-Diethyl hexanedioate; Diethylester kyseliny adipove; Hexanedioic acid, 1,6-diethyl ester; NSC 19160 ... and infrared spectra of industrially important adipate esters, J. Chromatogr. Sci., 1993, 31, 6, 225-230, https://doi.org/ ...
more infohttps://webbook.nist.gov/cgi/cbook.cgi?ID=C141286&Units=SI&Mask=2000
Amphetamine adipate - DrugBank  Amphetamine adipate - DrugBank
Amfetamine adipate. UNII. Z58RH02W4M. CAS Number. 64770-51-0. Weight. Average: 281.352. Monoisotopic: 281.162708225. Chemical ... Amphetamine adipate. Drug Entry. Amphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant ...
more infohttps://www.drugbank.ca/salts/DBSALT001323
Diisotridecyl adipate - Registration Dossier - ECHA  Diisotridecyl adipate - Registration Dossier - ECHA
... such as Diisopropyl adipate (CAS 6938-94-9), Dibutyl adipate (CAS 105-99-7), Dihexyl adipate (CAS 110-33-8), Diisopropyl ... diisotridecyl adipate. Type of composition:. legal entity composition of the substance. State / form:. liquid. Reference ... 2008) the water solubility of 5.5 (± 0.22) μg/L for di(2- ethylhexyl) adipate (DEHA) was measured using the slow-stir method ... The test substance diisotridecyl adipate was demonstrated to be readily biodegradable in three OECD guideline 301-tests. ...
more infohttps://echa.europa.eu/registration-dossier/-/registered-dossier/16101/2/3
Diisotridecyl adipate - Registration Dossier - ECHA  Diisotridecyl adipate - Registration Dossier - ECHA
Data on carcinogenicity are not available for diisotridecyl adipate. Data on di-2-ethylhexyl adipate (DEHA) as supporting ... For diisotridecyl adipate, the same is valid. There are no data that are contradictory or provide evidence that diisotridecyl ... The same statement is considered for the test substance diisotridecyl adipate. At very high doses (1715 and 3750 mg/kg) ... Overall, these findings suggest that the increased incidence of liver tumours in mice treated with di(2 -ethylhexyl)adipate ...
more infohttps://echa.europa.eu/registration-dossier/-/registered-dossier/16101/7/8
Dibutyl Adipate | Cosmetics Info  Dibutyl Adipate | Cosmetics Info
Dibutyl Adipate was observed to be a low level skin and eye irritant and a non-sensitizer. Dibutyl Adipate was not genotoxic in ... Dibutyl Adipate is the diester of butyl alcohol. and adipic acid. Another technical name for Dibutyl Adipate is Hexanedioic ... Dibutyl Adipate produced no effect. The CIR Expert Panel recognized that use of Dibutyl Adipate in suntan cosmetic products ... Dibutyl Adipate is the diester of butyl alcohol. and adipic acid. It is a clear colorless oily liquid. In cosmetics and ...
more infohttp://www.cosmeticsinfo.org/ingredient/dibutyl-adipate-0
Browse Products Containing: DIISOPROPYL ADIPATE || Skin Deep® Cosmetics Database | EWG  Browse Products Containing: DIISOPROPYL ADIPATE || Skin Deep® Cosmetics Database | EWG
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
more infohttps://www.ewg.org/skindeep/browse.php?comp_id=38&ingred06=701990
Browse Products Containing: DIISODECYL ADIPATE || Skin Deep® Cosmetics Database | EWG  Browse Products Containing: DIISODECYL ADIPATE || Skin Deep® Cosmetics Database | EWG
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
more infohttp://www.ewg.org/skindeep/browse.php?comp_id=471&ingred06=701988
SPECTRUM Di N Alkyl Adipate,25ml - 26XD27|A1386-25ML - Grainger  SPECTRUM Di N Alkyl Adipate,25ml - 26XD27|A1386-25ML - Grainger
Looking for SPECTRUM Di N Alkyl Adipate,25ml (26XD27)? Grainger's got your back. Price:$37.90. Easy ordering & convenient ...
more infohttps://www.grainger.com/product/SPECTRUM-Di-N-Alkyl-Adipate-26XD27
Dioctyl adipate - toxicity, ecological toxicity and regulatory information  Dioctyl adipate - toxicity, ecological toxicity and regulatory information
... adipate , Di(2-ethylhexyl)adipate , Dioctyl adipate , DIOCTYL ADIPATE (CA DPR Chem Code Text ) , Dioctyladipate , is(2- ... Di-capryl adipate. View. View. View. Adjuvant. No. Not Listed. Related. 1. Diisopropyl adipate. View. View. View. No. Not ... Dimethyl adipate. View. View. View. Adjuvant, Solvent. No. Not Listed. 103-23-1. Related. 1. Dioctyl adipate. View. View. View ... Dioctyl adipate Adipic acid Illinois EPA list. Keith list. Colborn list. Benbrook list. Danish Inert list. EU list. Not listed ...
more infohttp://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC35503
Diisopropyl adipate - toxicity, ecological toxicity and regulatory information  Diisopropyl adipate - toxicity, ecological toxicity and regulatory information
Di-capryl adipate. View. View. View. Adjuvant. No. Not Listed. Related. 1. Diisopropyl adipate. View. View. View. No. Not ... Dimethyl adipate. View. View. View. Adjuvant, Solvent. No. Not Listed. 103-23-1. Related. 1. Dioctyl adipate. View. View. View ... US EPA PC Code ) , 5846 (CA DPR Chem Code) ) , 900072 (US EPA PC Code Text ) , Diisopropyl Adipate , DIISOPROPYL ADIPATE (CA ... Diisopropyl adipate Adipic acid Illinois EPA list. Keith list. Colborn list. Benbrook list. Danish Inert list. EU list. Not ...
more infohttp://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC41581
Adipate - Wikipedia  Adipate - Wikipedia
Potassium adipate (E357) Some adipate esters are used as plasticizers, including: Bis(2-ethylhexyl) adipate Dioctyl adipate ... The anionic (HO2C(CH2)4CO2−) and dianionic (−O2C(CH2)4CO2−) forms of adipic acid are also referred to as adipate. Some adipate ... Adipates are the salts and esters of adipic acid. ...
more infohttps://en.wikipedia.org/wiki/Adipate
Spiramycin adipate (CAS 1405-20-5) Market Research Report 2018  Spiramycin adipate (CAS 1405-20-5) Market Research Report 2018
Market Research Report 2018 aims at providing comprehensive data on spiramycin adipate market globally and regionally ... Spiramycin adipate prices in other regions. 7. SPIRAMYCIN ADIPATE END-USE SECTOR 7.1. Spiramycin adipate market by application ... 6. SPIRAMYCIN ADIPATE MARKET PRICES. 6.1. Spiramycin adipate prices in Europe. 6.2. Spiramycin adipate prices in Asia 6.3. ... 2. SPIRAMYCIN ADIPATE APPLICATIONS. 2.1. Spiramycin adipate application spheres, downstream products. 3. SPIRAMYCIN ADIPATE ...
more infohttps://marketpublishers.com/report/industry/chemicals_petrochemicals/spiramycin_adipate_1405-20-5_market_research_report.html
Potassium adipate - Wikipedia  Potassium adipate - Wikipedia
Potassium adipate is a compound with formula K2C6H8O4. It is the potassium salt of adipic acid. It has E number "E357". Sodium ...
more infohttps://en.wikipedia.org/wiki/Potassium_adipate
Global Monoethyl Adipate (MEA) Market Research Report to 2018 : ReportsnReports  Global Monoethyl Adipate (MEA) Market Research Report to 2018 : ReportsnReports
128 Pages Report] Check for Discount on Global Monoethyl Adipate (MEA) Market Research Report to 2018 report by HeyReport. ... Figure Global Monoethyl Adipate (MEA) Market Size and CAGR 2011-2017 (Million USD). Figure Global Monoethyl Adipate (MEA) ... Figure Global Monoethyl Adipate (MEA) Market Forecast and CAGR 2018-2025 (Million USD). Figure Global Monoethyl Adipate (MEA) ... Figure Europe Monoethyl Adipate (MEA) Market Size and CAGR 2011-2017 (Million USD). Figure Europe Monoethyl Adipate (MEA) ...
more infohttp://www.reportsnreports.com/reports/1432550-global-monoethyl-adipate-mea-market-research-report-to-2018.html
Piperazine Adipate in Rajkot,Piperazine Adipate Manufacturers and Suppliers from india  Piperazine Adipate in Rajkot,Piperazine Adipate Manufacturers and Suppliers from india
Get contact details of Piperazine Adipate Manufacturers, Wholesale Piperazine Adipate Exporters, Best Piperazine Adipate ... Business Directory for Piperazine Adipate Suppliers in Rajkot - ... Piperazine Adipate in Rajkot. * * Cities : Eluru , Ahmedabad , ... piperazine adipate, Aluminium Sulphate, Poly Aluminium Chloride, Sodium Carboxymethyl Cellulose, Polyaluminum Chloride... ...
more infohttp://www.indianyellowpages.com/rajkot/piperazine-adipate.htm
Polymers | Free Full-Text | Extrusion 3D Printing of Polybutyrate-Adipate-Terephthalate-Polymer Composites in the Pellet Form  Polymers | Free Full-Text | Extrusion 3D Printing of Polybutyrate-Adipate-Terephthalate-Polymer Composites in the Pellet Form
The current research is focused on evaluating polybutyrate-adipate-terephthalate-polymer (PBAT) for fused deposition modelling ... Extrusion 3D Printing of Polybutyrate-Adipate-Terephthalate-Polymer Composites in the Pellet Form Sarat Singamneni 1,*, Dawn ... Singamneni S, Smith D, LeGuen M-J, Truong D. Extrusion 3D Printing of Polybutyrate-Adipate-Terephthalate-Polymer Composites in ... "Extrusion 3D Printing of Polybutyrate-Adipate-Terephthalate-Polymer Composites in the Pellet Form." Polymers 10, no. 8: 922. ...
more infohttps://www.mdpi.com/2073-4360/10/8/922
Chain Extension of Poly(butylene adipate) with 2,2-(1,4- Phenylene)-bis(2-oxazoline)  Chain Extension of Poly(butylene adipate) with 2,2'-(1,4- Phenylene)-bis(2-oxazoline)
... butylene adipate) (PBA) was synthesized by melt polycondensation. The chain extension of the prepolymers was carried out using ... S. Y. Luo et al., "Chain Extension of Poly(butylene adipate) with 2,2'-(1,4- Phenylene)-bis(2-oxazoline)", Advanced Materials ... HomeAdvanced Materials ResearchAICAM 2005Chain Extension of Poly(butylene adipate) with... ... Low molecular weight poly(butylene adipate) (PBA) was synthesized by melt polycondensation. The chain extension of the ...
more infohttps://www.scientific.net/AMR.11-12.387
In vitro dermal absorption of di(2-ethylhexyl) adipate (DEHA) in a roll-on deodorant using human skin. | Sigma-Aldrich  In vitro dermal absorption of di(2-ethylhexyl) adipate (DEHA) in a roll-on deodorant using human skin. | Sigma-Aldrich
In vitro dermal absorption of di(2-ethylhexyl) adipate (DEHA) in a roll-on deodorant using human skin.. [Simon Ningsun Zhou, ... Bis(2-ethylhexyl) adipate, Selectophore™, ≥99.0% C22H42O4 ... Bis(2-ethylhexyl) adipate, ≥97.0% (GC) C22H42O4 ... Bis(2-ethylhexyl) adipate, analytical standard C22H42O4 ... adipate solution, certified reference material, 2000 μg/mL in ... In vitro dermal absorption experiments were conducted using a roll-on deodorant that contains 1.56% di(2-ethylhexyl) adipate ( ...
more infohttps://www.sigmaaldrich.com/catalog/papers/23356645
2016 Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate (CAS 3130-19-6) Industry Market Report : ReportsnReports  2016 Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate (CAS 3130-19-6) Industry Market Report : ReportsnReports
The ''Global and Chinese Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate... ... 150 Pages Report] Check for Discount on 2016 Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate (CAS 3130-19-6) Industry Market Report ... 1.1 Brief Introduction of Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate 1.2 Development of Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate ... Chapter Nine Market Dynamics of Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate Industry 9.1 Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate ...
more infohttp://www.reportsnreports.com/reports/671927-2016-bis-34-epoxycyclohexyl-methyladipate-cas-3130-19-6-industry-market-report.html
Adipates - Plasticisers - Information Center  Adipates - Plasticisers - Information Center
Benzyl 2-ethylhexyl adipate. BOA. 905-983-8. Yes. Not class.. Adipate. Di-2-ethylhexyl adipate. DEHA. 103-23-1. 203-090-1. Yes ... Adipate. Diisononyl adipate. DINA. 33703-08-1. 291-426-8. Yes. Adhesives & Sealants, Food packaging - Cling Wrap. Not class.. ... Adipate. Bis[2-(2-butoxyethoxy)ethyl]adipate. DBEEA. 141-17-3. 205-465-5. Yes. Not class.. ... Adipate. Di-n-butyl adipate. DBA. 105-99-7. 203-350-4. Yes. Not class.. ...
more infohttps://www.plasticisers.org/plasticiser/adipates/
  • Novel Poly (glycerol-adipate) Polymers Used for Nanoparticle Making: A Study of Surface Free Energy', Iranian Journal of Pharmaceutical Research , Volume 7(Number 1), pp. 11-19. (ac.ir)
  • New glycerol adipate polymers with hydroxyl group substituted with different percent of acyl group, sited as figures within the abbreviated name in the text, and triptophan were synthesized and proposed to be used in the preparction of dexamethason phosphate loaded nanoparticles, using the evaporation-deposition technique. (ac.ir)
  • Development of poly(glycerol adipate) nanoparticles loaded with non-steroidal anti-inflammatory drugs. (ru.nl)
  • The aim of this study was to assess acylated and non-acylated poly(glycerol adipate) polymers (PGA) as suitable nanoparticulate systems for encapsulation and release of ibuprofen, ibuprofen sodium salt (IBU-Na) and ketoprofen as model drugs. (ru.nl)
  • Bis[2-(2-butoxyethoxy)ethyl]adipate, is used to improve cold flexibility and/or hydrocarbons extraction in both PVC and polar rubbers compounds. (plasticisers.org)
  • The CIR Expert Panel evaluated the scientific data and concluded that Dibutyl Adipate was safe for use as a cosmetic ingredient. (cosmeticsinfo.org)
  • Combined with the data demonstrating very little acute toxicity, no skin or ocular irritation, and no reproductive or developmental toxicity, these data provided an adequate basis for reaching a conclusion that Dibutyl Adipate was safe as a cosmetic and personal care product ingredient. (cosmeticsinfo.org)
  • Spiramycin adipate (CAS 1405-20-5) Market Research Report 2018 aims at providing comprehensive data on spiramycin adipate market globally and regionally (Europe, Asia, North America, Latin America etc. (marketpublishers.com)
  • Spiramycin adipate (CAS 1405-20-5) Market Research Report 2018 contents were prepared and placed on the website in January, 2018. (marketpublishers.com)
  • Please note that Spiramycin adipate (CAS 1405-20-5) Market Research Report 2018 is a half ready publication and contents are subject to change. (marketpublishers.com)
  • Adipates are colourless and odourless and they are used in a number of coating, washing and cleaning applications, lubricants and greases, plant protection products, adhesive and sealants, polishes and waxes. (plasticisers.org)
  • In cosmetics and personal care products, Dibutyl Adipate is used in nail polish and skin care products. (cosmeticsinfo.org)
  • The CIR Expert Panel recognized that use of Dibutyl Adipate in suntan cosmetic products will result in repeated, frequent exposure in a leave-on product. (cosmeticsinfo.org)
  • Dibutyl Adipate may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union . (cosmeticsinfo.org)
  • The report provides key statistics on the market status of the Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.Firstly, the report provides a basic overview of the industry including its definition, applications and manufacturing technology. (reportsnreports.com)
  • We do this by working with competitive and reliable manufacturers of Dicapryl Adipate. (wegochem.com)
  • Wego supplies Dicapryl Adipate to users/customers for Personal Care & Cosmetics. (wegochem.com)
  • Data on carcinogenicity are not available for diisotridecyl adipate. (europa.eu)
  • There are no data that are contradictory or provide evidence that diisotridecyl adipate would induce hyperplasia or pre-neoplastic lesions. (europa.eu)
  • In addition to the above the report determines spiramycin adipate consumers. (marketpublishers.com)
  • The ''Global and Chinese Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate Industry, 2011-2021 Market Research Report'' is a professional and in-depth study on the current state of the global Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate industry with a focus on the Chinese market. (reportsnreports.com)
  • Through the statistical analysis, the report depicts the global and Chinese total market of Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate industry including capacity, production, production value, cost/profit, supply/demand and Chinese import/export. (reportsnreports.com)
  • The report then estimates 2016-2021 market development trends of Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate industry. (reportsnreports.com)
  • In the end, the report makes some important proposals for a new project of Bis[(3,4-Epoxycyclohexyl)Methyl]Adipate Industry before evaluating its feasibility. (reportsnreports.com)
  • Hepatic peroxisome proliferation has not been evaluated in studies of human subjects or systems treated with di(2 -ethylhexyl) adipate. (europa.eu)
  • However, studies of di(2 -ethylhexyl) adipate or its metabolites regarding peroxisome proliferation in human cells are not available (IARC, Vol.77). (europa.eu)