Adhesiveness. Medical search

A property of the surface of an object that makes it stick to another surface.

Adherence of cells to surfaces or to other cells.

The process whereby PLATELETS adhere to something other than platelets, e.g., COLLAGEN; BASEMENT MEMBRANE; MICROFIBRILS; or other "foreign" surfaces.

The phenomenon by which dissociated cells intermixed in vitro tend to group themselves with cells of their own type.

Surface ligands, usually glycoproteins, that mediate cell-to-cell adhesion. Their functions include the assembly and interconnection of various vertebrate systems, as well as maintenance of tissue integration, wound healing, morphogenic movements, cellular migrations, and metastasis.

Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.

A cell-surface ligand involved in leukocyte adhesion and inflammation. Its production is induced by gamma-interferon and it is required for neutrophil migration into inflamed tissue.

Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.

Cytokine-induced cell adhesion molecule present on activated endothelial cells, tissue macrophages, dendritic cells, bone marrow fibroblasts, myoblasts, and myotubes. It is important for the recruitment of leukocytes to sites of inflammation. (From Pigott & Power, The Adhesion Molecule FactsBook, 1993, p154)

Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)

A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.

Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.

White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).

The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.

An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (ANTIGENS, CD18) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.

Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.

Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.

Cell adhesion molecule and CD antigen that mediates neutrophil, monocyte, and memory T-cell adhesion to cytokine-activated endothelial cells. E-selectin recognizes sialylated carbohydrate groups related to the Lewis X or Lewis A family.

A family of transmembrane glycoproteins (MEMBRANE GLYCOPROTEINS) consisting of noncovalent heterodimers. They interact with a wide variety of ligands including EXTRACELLULAR MATRIX PROTEINS; COMPLEMENT, and other cells, while their intracellular domains interact with the CYTOSKELETON. The integrins consist of at least three identified families: the cytoadhesin receptors(RECEPTORS, CYTOADHESIN), the leukocyte adhesion receptors (RECEPTORS, LEUKOCYTE ADHESION), and the VERY LATE ANTIGEN RECEPTORS. Each family contains a common beta-subunit (INTEGRIN BETA CHAINS) combined with one or more distinct alpha-subunits (INTEGRIN ALPHA CHAINS). These receptors participate in cell-matrix and cell-cell adhesion in many physiologically important processes, including embryological development; HEMOSTASIS; THROMBOSIS; WOUND HEALING; immune and nonimmune defense mechanisms; and oncogenic transformation.

Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.

Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.

The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.

Characteristics or attributes of the outer boundaries of objects, including molecules.

Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.

Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.

Established cell cultures that have the potential to propagate indefinitely.

A cytoskeletal protein associated with cell-cell and cell-matrix interactions. The amino acid sequence of human vinculin has been determined. The protein consists of 1066 amino acid residues and its gene has been assigned to chromosome 10.

The network of filaments, tubules, and interconnecting filamentous bridges which give shape, structure, and organization to the cytoplasm.

Direct contact of a cell with a neighboring cell. Most such junctions are too small to be resolved by light microscopy, but they can be visualized by conventional or freeze-fracture electron microscopy, both of which show that the interacting CELL MEMBRANE and often the underlying CYTOPLASM and the intervening EXTRACELLULAR SPACE are highly specialized in these regions. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p792)

Transmembrane proteins consisting of a lectin-like domain, an epidermal growth factor-like domain, and a variable number of domains that are homologous to complement regulatory proteins. They are important cell adhesion molecules which help LEUKOCYTES attach to VASCULAR ENDOTHELIUM.

Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.

Laboratory tests for evaluating the individual's clotting mechanism.

Hard, amorphous, brittle, inorganic, usually transparent, polymerous silicate of basic oxides, usually potassium or sodium. It is used in the form of hard sheets, vessels, tubing, fibers, ceramics, beads, etc.

Polymeric resins derived from OXIRANES and characterized by strength and thermosetting properties. Epoxy resins are often used as dental materials.

Venous vessels in the umbilical cord. They carry oxygenated, nutrient-rich blood from the mother to the FETUS via the PLACENTA. In humans, there is normally one umbilical vein.

Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells.

The movement of leukocytes in response to a chemical concentration gradient or to products formed in an immunologic reaction.

Distinct regions of mesenchymal outgrowth at both flanks of an embryo during the SOMITE period. Limb buds, covered by ECTODERM, give rise to forelimb, hindlimb, and eventual functional limb structures. Limb bud cultures are used to study CELL DIFFERENTIATION; ORGANOGENESIS; and MORPHOGENESIS.

The surgical removal of the eyeball leaving the eye muscles and remaining orbital contents intact.

A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.

A cytotoxic member of the CYTOCHALASINS.

A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.

A type of junction that attaches one cell to its neighbor. One of a number of differentiated regions which occur, for example, where the cytoplasmic membranes of adjacent epithelial cells are closely apposed. It consists of a circular region of each membrane together with associated intracellular microfilaments and an intercellular material which may include, for example, mucopolysaccharides. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990; Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)

A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body.

The layer of pigment-containing epithelial cells in the RETINA; the CILIARY BODY; and the IRIS in the eye.

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.

An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.

Thin, hairlike appendages, 1 to 20 microns in length and often occurring in large numbers, present on the cells of gram-negative bacteria, particularly Enterobacteriaceae and Neisseria. Unlike flagella, they do not possess motility, but being protein (pilin) in nature, they possess antigenic and hemagglutinating properties. They are of medical importance because some fimbriae mediate the attachment of bacteria to cells via adhesins (ADHESINS, BACTERIAL). Bacterial fimbriae refer to common pili, to be distinguished from the preferred use of "pili", which is confined to sex pili (PILI, SEX).

A series of steps taken in order to conduct research.

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

A type of analysis in which subjects in a study group and a comparison group are made comparable with respect to extraneous factors by individually pairing study subjects with the comparison group subjects (e.g., age-matched controls).

A group of three different alpha chains (CD11a, CD11b, CD11c) that are associated with an invariant CD18 beta chain (ANTIGENS, CD18). The three resulting leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE ADHESION) are LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MACROPHAGE-1 ANTIGEN; and ANTIGEN, P150,95.

A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).

Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion.

Integrin beta-1 chains which are expressed as heterodimers that are noncovalently associated with specific alpha-chains of the CD49 family (CD49a-f). CD29 is expressed on resting and activated leukocytes and is a marker for all of the very late activation antigens on cells. (from: Barclay et al., The Leukocyte Antigen FactsBook, 1993, p164)

Elements of limited time intervals, contributing to particular results or situations.

The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.

Chemical substances that attract or repel cells. The concept denotes especially those factors released as a result of tissue injury, microbial invasion, or immunologic activity, that attract LEUKOCYTES; MACROPHAGES; or other cells to the site of infection or insult.

A form of interference microscopy in which variations of the refracting index in the object are converted into variations of intensity in the image. This is achieved by the action of a phase plate.

Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.

A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).

The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY.

The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.

The aggregation of ERYTHROCYTES by AGGLUTININS, including antibodies, lectins, and viral proteins (HEMAGGLUTINATION, VIRAL).

A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.

The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.

Cell adhesion molecule and CD antigen that serves as a homing receptor for lymphocytes to lymph node high endothelial venules.

A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.

The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.

An adhesion procedure for orthodontic attachments, such as plastic DENTAL CROWNS. This process usually includes the application of an adhesive material (DENTAL CEMENTS) and letting it harden in-place by light or chemical curing.

Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.

Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.

The quantity of volume or surface area of CELLS.

A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.

Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.

Antibodies produced by a single clone of cells.

Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.

The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.

Any of several ways in which living cells of an organism communicate with one another, whether by direct contact between cells or by means of chemical signals carried by neurotransmitter substances, hormones, and cyclic AMP.

Acrylic acids or acrylates which are substituted in the C-2 position with a methyl group.

Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage.

Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible.

Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.

A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.

The natural enzymatic dissolution of FIBRIN.

Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.

The residual portion of BLOOD that is left after removal of BLOOD CELLS by CENTRIFUGATION without prior BLOOD COAGULATION.

The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.

The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)

The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.

Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.

Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation.

The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.

A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.

White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.

Microscopy of specimens stained with fluorescent dye (usually fluorescein isothiocyanate) or of naturally fluorescent materials, which emit light when exposed to ultraviolet or blue light. Immunofluorescence microscopy utilizes antibodies that are labeled with fluorescent dye.

The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.

Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.

Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules.

The movement of cells or organisms toward or away from a substance in response to its concentration gradient.

The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.

Peptides composed of between two and twelve amino acids.

One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.

A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.

Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).

A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.

A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.

Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.

The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)

Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.

Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.

Ability of neoplasms to infiltrate and actively destroy surrounding tissue.

Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.

The rate dynamics in chemical or physical systems.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.

The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.

A group of genetically identical cells all descended from a single common ancestral cell by mitosis in eukaryotes or by binary fission in prokaryotes. Clone cells also include populations of recombinant DNA molecules all carrying the same inserted sequence. (From King & Stansfield, Dictionary of Genetics, 4th ed)

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.

An essential amino acid that is physiologically active in the L-form.

A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.

Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls and may be isolated.

A cell line derived from cultured tumor cells.

The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.

Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.

The main trunk of the systemic arteries.

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

Glycoproteins found on the membrane or surface of cells.

Proteins prepared by recombinant DNA technology.

The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

The parts of a macromolecule that directly participate in its specific combination with another molecule.

A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)

A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.

The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.

Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.

The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

The relationship between the dose of an administered drug and the response of the organism to the drug.

Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.

An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.

All of the processes involved in increasing CELL NUMBER including CELL DIVISION.

The forward rate of binding of surface-tethered reactants: effect of relative motion between two surfaces. (1/1085)

The reaction of molecules confined to two dimensions is of interest in cell adhesion, specifically for the reaction between cell surface receptors and substrate-bound ligand. We have developed a model to describe the overall rate of reaction of species that are bound to surfaces under relative motion, such that the Peclet number is order one or greater. The encounter rate between reactive species is calculated from solution of the two-dimensional convection-diffusion equation. The probability that each encounter will lead to binding depends on the intrinsic rate of reaction and the encounter duration. The encounter duration is obtained from the theory of first passage times. We find that the binding rate increases with relative velocity between the two surfaces, then reaches a plateau. This plateau indicates that the increase in the encounter rate is counterbalanced by the decrease in the encounter duration as the relative velocity increases. The binding rate is fully described by two dimensionless parameters, the Peclet number and the Damkohler number. We use this model to explain data from the cell adhesion literature by incorporating these rate laws into "adhesive dynamics" simulations to model the binding of a cell to a surface under flow. Leukocytes are known to display a "shear threshold effect" when binding selectin-coated surfaces under shear flow, defined as an increase in bind rate with shear; this effect, as calculated here, is due to an increase in collisions between receptor and ligand with increasing shear. The model can be used to explain other published data on the effect of wall shear rate on the binding of cells to surfaces, specifically the mild decrease in binding within a fixed area with increasing shear rate. (+info)

Adhesion energy of receptor-mediated interaction measured by elastic deformation. (2/1085)

We investigated the role of receptor binding affinity in surface adhesion. A sensitive technique was developed to measure the surface energy of receptor-mediated adhesion. The experimental system involved a functionalized elastic agarose bead resting on a functionalized glass coverslip. Attractive intersurface forces pulled the two surfaces together, deforming the bead to produce an enlarged contact area. The Johnson-Kendall-Roberts (JKR) model was used to relate the surface energy of the interaction to the elasticity of the bead and the area of contact. The surface energies for different combinations of modified surfaces in solution were obtained from reflection interference contrast microscopy (RICM) measurements of the contact area formed by the bead and the coverslip. Studies with surfaces functionalized with ligand-receptor pairs showed that the relationship between surface energy and the association constant of the ligand binding has two regimes. At low binding affinity, surface energy increased linearly with the association constant, while surface energy increased logarithmically with the association constant in the high affinity regime. (+info)

Steric effects of N-acyl group in O-methacryloyl-N-acyl tyrosines on the adhesiveness of unetched human dentin. (3/1085)

We have prepared various O-methacryloyl-N-acyl tyrosines (MAATY) to reveal the relationship between molecular structure near carboxylic acid and adhesive strength of MAATY-HEMA type adhesive resin to unetched dentin. In this study, we attempted to change the steric hindrance effect without changing the HLB value, i.e., introducing an iso-acyl group instead of n-acyl group into MAATY. O-methacryloyl-N-ethylbutyryl tyrosine (MIHTY) showed significantly lower adhesive strength when compared with O-methacryloyl-N-hexanoyl tyrosine even though both MAATY have the same HLB value. The possible explanation of the significantly different adhesive strength was that the 2-ethylbutyryl group in MIHTY was bulky, resulting in inhibition of the hydrogen bonding of the carboxylic group. The HLB value is independent of the steric effect of molecular structure, and thus the steric factor should be taken into consideration for the explanation of different adhesive strengths within the adhesive monomers having the same HLB value but different molecular structures. (+info)

Adhesion of adhesive resin to dental precious metal alloys. Part I. New precious metal alloys with base metals for resin bonding. (4/1085)

New dental precious metal alloys for resin bonding without alloy surface modification were developed by adding base metals (In, Zn, or Sn). Before this, binary alloys of Au, Ag, Cu, or Pd containing In, Zn, or Sn were studied for water durability and bonding strength with 4-META resin. The adhesion ability of the binary alloys was improved by adding In equivalent to 15% of Au content, Zn equivalent to 20% of Ag content, and In, Zn, or Sn equivalent to 5% of Cu content. There was no addition effect of the base metals on Pd, however 15% of In addition improved adhesion with Pd-based alloys containing equi-atomic % of Cu and Pd. The alloy surfaces were analyzed by XPS and showed that oxides such as In2O3, ZnO, or SnO play an important role in improving the adhesive ability of the alloys. (+info)

Adhesion of adhesive resin to dental precious metal alloys. Part II. The relationship between surface structure of Au-In alloys and adhesive ability with 4-META resin. (5/1085)

Adhesion of 4-META to Au-In alloy was improved by adding In equivalent to .15% of Au content. On the basis of the results of Au-In alloys analyzed by XPS, the present study investigated the reason why adhesion of the Au-In alloy was improved. The O 1s spectrum could be separated into three oxygen chemical states, In2O3, chemisorbed H2O, and physisorbed H2O. The amount of chemisorbed H2O decreased remarkably with increasing amount of In. It is considered that the poor adhesive ability of the pure gold and alloys containing only small amounts of In was due to the chemisorbed H2O molecules and insufficient indium oxide on the alloy surface. It was established that excellent adhesion requires an oxide with chemical affinity for 4-META to cover at least 50% of the alloy surface. (+info)

Coating of extracorporeal circuit with heparin does not prevent sequestration of propofol in vitro. (6/1085)

Propofol is sequestered in extracorporeal circuits, but the factors responsible for the phenomenon are mostly unknown. We have compared two extracorporeal circuits (oxygenators, reservoirs and tubings) coated with heparin with two corresponding uncoated circuits for their capacity to sequester propofol in vitro. Three experiments were conducted with each circuit. The circuit was primed with a mixture of Ringer's acetate solution and whole blood, and the study conditions (pump flow, temperature, pH) were standardized. Propofol was added to the solution to achieve a concentration of 2 micrograms ml-1. These studies were followed with concentrations of 10- and 100-fold to assess possible saturation of propofol binding. Serial samples were obtained from the circulating solution for measurement of propofol concentration. Propofol concentrations decreased to 22-32% of the initial predicted concentration of 2 micrograms ml-1 in the circuits (no significant difference between circuits). With greater concentrations, the circuits did not become saturated with propofol, even with the highest predicted concentration of 200 micrograms ml-1. We conclude that propofol was sequestered in extracorporeal circuits in vitro, irrespective of coating the circuit with heparin. (+info)

An ex vivo investigation into the bond strength of orthodontic brackets and adhesive systems. (7/1085)

The aim of this study was to compare the shear bond strength of Adhesive Precoated Brackets (APC) with that of two types of uncoated bracket bases, Straight-Wire and Dyna-Lock. Two types of orthodontic adhesives were used, Transbond XT and Right-On. Three different curing times were evaluated with the APC brackets in order to find the best. Adhesive remnants on the enamel surface following debond were evaluated using the Adhesive Remnant Index (Artun and Bergland, 1984). Bond strengths ranged from 11.00 to 22.08 MPa. For both types of brackets Transbond produced a significant increase in bond strength compared to Right-On. The Dyna-Lock/Right-On combination produced the poorest results. APC brackets cured for 40 s had similar bond strengths to uncoated brackets fixed by means of Transbond. Overall, 79 per cent of specimens had less than half the tooth surface covered with adhesive following debond. Significantly more adhesive remained on tooth surfaces following debond of the Straight-Wire/Right-On group than any other bracket/adhesive combination. Bond strengths were higher with light-cured Transbond than with chemically-cured Right-On. When Transbond is used in association with APC brackets a 40-second cure time is recommended. (+info)

The influence of epitope availability on atomic-force microscope studies of antigen-antibody interactions. (8/1085)

The ability of the atomic-force microscope (AFM) to detect interaction forces between individual biological molecules has recently been demonstrated. In this study, force measurements have been obtained between AFM probes functionalized with the beta-subunit of human chorionic gonadotrophin (betahCG) and surfaces functionalized with anti-betahCG antibody. A comparison of the obtained results with previous anti-ferritin antibody-binding data identifies differences when the antigen molecule expresses only a single epitope (betahCG), rather than multiple epitopes (ferritin), for the monoclonal antibodies employed. Specifically, the probability of observing probe-sample adhesion is found to be higher when the antigen expresses multiple epitopes. However, the periodic force observed in the adhesive-force distribution, due to the rupture of single antigen-antibody interactions, is found to be larger and more clearly observed for the mono-epitopic system. Hence, these findings indicate the potential of the AFM to distinguish between multivalent and monovalent antibody-antigen interactions, and demonstrate the influence of the number of expressed epitopes upon such binding studies. (+info)

They possess no obvious adhesiveness. Eggs were seen to hatch after seven days at 22-24 °C (72-75 °F). Hatched larvae are 3.5 ...

https://en.wikipedia.org/wiki/Carinotetraodon_imitator

Phillips, Herbert M.; Steinberg, Malcolm S. (1969). "Equilibrium measurements of embryonic chick cell adhesiveness. I. Shape ... differential adhesiveness, and the absence of directed migration". Proc Natl Acad Sci USA. 48 (9): 1577-1582. Bibcode:1962PNAS ...

https://en.wikipedia.org/wiki/Malcolm_Steinberg

Van Itallie CM, Anderson JM (May 1997). "Occludin confers adhesiveness when expressed in fibroblasts". Journal of Cell Science ...

https://en.wikipedia.org/wiki/Occludin

Rizzo, E.; Sato, Y.; Barreto, B. P.; Godinho, Hugo P. (September 2002). "Adhesiveness and surface patterns of eggs in ... "Oocyte adhesiveness and embryonic development of Astyanax bimaculatus (Linnaeus, 1758) (Pisces: Characidae)". Zygote. 21 (2): ...

https://en.wikipedia.org/wiki/Orangefin_tetra

"Coaggregation ability ofWeissella cibariaisolates withFusobacterium nucleatumand their adhesiveness to epithelial cells". FEMS ...

https://en.wikipedia.org/wiki/Weissella_cibaria

2002). Adhesiveness and surface patterns of eggs in neotropical freshwater teleosts. Journal of Fish Biology. 61. 615-632. ... Oocyte adhesiveness and embryonic development of Astyanax bimaculatus (Linnaeus, 1758) (Pisces: Characidae): Zygote; Cambridge ...

https://en.wikipedia.org/wiki/Bryconops

This imparts adhesiveness to both the red and the white blood cells, making them prone to stick to one another and to the walls ... Lister performed these experiments to discover the causes of erythrocyte adhesiveness. As well as experimenting on frogs web ... that when blood is removed from the body this aggregation depends on their possessing a certain degree of mutual adhesiveness, ...

https://en.wikipedia.org/wiki/Joseph_Lister

Heat and light intensities can also cause sticky traps to loose their adhesiveness. Pollen traps are used to measure production ...

https://en.wikipedia.org/wiki/Seed_trap

CASGAGs are important in providing support and adhesiveness in bone, skin, and cartilage. Other biological functions for which ...

https://en.wikipedia.org/wiki/Glycosaminoglycan

Xia, Yu; Wang, Yubo; Wang, Yi; Chin, Francis Y. L.; Zhang, Tong (23 May 2016). "Cellular adhesiveness and cellulolytic capacity ...

https://en.wikipedia.org/wiki/Anaerolinea

... and foreign surface adhesiveness of human leukocytes". The American Journal of Pathology. 90 (3): 537-50. PMC 2018255. PMID ... these responses result from an increase in neutrophil adhesiveness to each other and/or vascular endothelium); the release (see ...

https://en.wikipedia.org/wiki/N-Formylmethionine-leucyl-phenylalanine

"Adhesive Hydrogel Patch with Enhanced Strength and Adhesiveness to Skin for Transdermal Drug Delivery". Advanced Functional ...

https://en.wikipedia.org/wiki/Magnesium_oil

Next to a TCR signaling PTPN22 regulates an adhesiveness and a motility of T cells. PTPN22-deficient T cells have a prolonged ... Part of the reason of the increased adhesiveness of those T cells is that enhanced TCR signaling results in a higher activation ...

https://en.wikipedia.org/wiki/PTPN22

Berg, KJ; Skaga, E; Skjaeggestad, O; Stormorken, H (13 November 1965). "Effect of linseed oil on platelet adhesiveness and ...

https://en.wikipedia.org/wiki/Helge_Stormorken

As additive to solid polymers to enchance adhesiveness to glass, steel or wood.[better source needed] As a binder for porcelian ...

https://en.wikipedia.org/wiki/Tetraethyl_orthosilicate

This adhesiveness is so powerful that bending the profiles is possible even at very low radii, thus broadening significantly ... The optimal adhesiveness between these two materials is made possible by applying a coextruded intermediate adhesive layer. The ...

https://en.wikipedia.org/wiki/Hybrid_wood

It is also used for the functionalization of polymer surfaces by UV-induced grafting to improve wettability and adhesiveness. 1 ...

https://en.wikipedia.org/wiki/1-Vinylimidazole

... showed in vivo and in vitro synergistic activity with antibiotics, against bacterial adhesiveness, in patients with ...

https://en.wikipedia.org/wiki/Erdosteine

Whitman uses the phrenological concept of adhesiveness in reference to one's propensity for friendship and camaraderie. Whitman ...

https://en.wikipedia.org/wiki/Leaves_of_Grass

"Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions". Blood. 114 (11 ...

https://en.wikipedia.org/wiki/FERMT3

Scott TG, Smyth CJ, Keane CT (February 1987). "In vitro adhesiveness and biotype of Gardnerella vaginalis strains in relation ...

https://en.wikipedia.org/wiki/Clue_cell

... and low platelet adhesiveness. Severity of platelet dysfunction typically correlates with clinical condition, with the most ...

https://en.wikipedia.org/wiki/Glycogen_storage_disease_type_I

... and L-selectin increases adhesiveness and shear resistance under hydrodynamic force". Nat Immunol. 7 (8): 883-9. doi:10.1038/ ...

https://en.wikipedia.org/wiki/EGF-like_domain

... and fibroblasts and increases platelet adhesiveness.[citation needed] Macroscopically, this affects healing and tissue ...

https://en.wikipedia.org/wiki/Periodontal_fiber

... of a population of human limbal epithelial cells with putative stem cell properties based on collagen type IV adhesiveness". ...

https://en.wikipedia.org/wiki/Limbal_ring

... s may change conformation, adhesiveness or water retention properties, due to slight changes in pH, ionic strength ...

https://en.wikipedia.org/wiki/Smart_polymer

... thicker bond lines than the thermal paste as it cures while still allowing an easy disassembly thanks to limited adhesiveness. ...

https://en.wikipedia.org/wiki/Thermal_interface_material

At the time of his death, he had an unfinished gay studies manuscript, The Age of Adhesiveness: From Friendship to ...

https://en.wikipedia.org/wiki/Michael_Lynch_(professor)

The CYTH1 is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the ...

https://en.wikipedia.org/wiki/CYTH1

... the letters dropping off due to the reduction in adhesiveness of the glue used to stick the white plastic letters onto the ...

https://en.wikipedia.org/wiki/Vehicle_registration_plates_of_Malaysia

Adhesiveness. Adhesiveness is evaluated by chewing the cheese several times, pressing it against the palate and considering the ...

https://www.granapadano.it/en-ww/adhesiveness.aspx

Determination of the Adhesiveness of Glue The Pleistocene Man of Vero, Florida A Review of the Latest Evidence and Theories ...

https://www.scientificamerican.com/magazine/supplements/1919/02-22/?error=cookies_not_supported&code=23434078-755b-498d-a636-cf100704d85b

... Author:. Shuali, Annika, Biomedical Engineering - ...

https://libraetd.lib.virginia.edu/public_view/9306sz488

... RFO UPF []. 2011 ...

http://revodonto.bvsalud.org/scielo.php?script=sci_abstract&pid=S1413-40122011000100016&lng=es&nrm=iso&tlng=en

The attachment of streptococci and staphylococci to cells infected with influenza virus has been previously reported and has been correlated with the increased incidence of these bacterial infections during flu epidemics. The present work was initiated to determine whether infection with herpes simp …

https://pubmed.ncbi.nlm.nih.gov/6306535/?dopt=Abstract

Skin damage due to dressing adhesiveness. 6. 19.4. 8. 25.8. Chi-square test and Mann-Whitney U test were utilized.. a ... No skin damage due to dressing adhesiveness. 25. 80.6. 23. 74.2. .544. ... and skin damage caused by the strong adhesiveness of the dressings were observed in both groups. In the hydrocolloid plate ...

https://www.medscape.com/viewarticle/916577

OF obedience, faith, adhesiveness;. As I stand aloof and look, there is to me something. profoundly affecting in large masses ...

https://poets.org/poem/song-myself-31

Dive into the research topics of Syntheses of O-Methacryloyl-N-Acyl Tyrosines and Their Adhesiveness to Un-etched Human Dentin ... Syntheses of O-Methacryloyl-N-Acyl Tyrosines and Their Adhesiveness to Un-etched Human Dentin. ...

https://okayama.pure.elsevier.com/en/publications/syntheses-of-o-methacryloyl-n-acyl-tyrosines-and-their-adhesivene/fingerprints/

Adhesiveness or Friendship: A feeling or attraction to become friendly with other persons, or to increase social contacts. ...

https://www.ocf.berkeley.edu/~jfkihlstrom/SocialCognitionWeb/SocNeuro/SocNeuro_supp.htm

Cranberry extract has inhibitory activity on the bacterial adhesiveness of pathogenic E. Coli. Apr 01, 2010. ...

https://greenmedinfo.com/disease/urinary-tract-infections

The electrodes are coated with gold to reduce adhesiveness. The probes are stiff in order to allow adequate pressure to be ...

https://emedicine.medscape.com/article/187857-treatment

Tenascin is known to reduce epithelial cell adhesiveness. It is absent in normal breast, its distribution being restricted to ...

https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-93-037.html

Study 19. Microbial Interactions/Pathogenicity flashcards from E E's class online, or in Brainscape's iPhone or Android app. ✓ Learn faster with spaced repetition.

https://www.brainscape.com/flashcards/19-microbial-interactions-pathogenicity-4083665/packs/5776417

0404] The function of the adhesive layer is to provide a satisfactory level of adhesiveness to the skin of the subject. This ... adhesiveness can be provided by certain macromolecular substances. Examples of such macromolecular substance are gelatin, agar ...

https://www.freepatentsonline.com/y2003/0211163.html

Scotch® Magic™ Tape is the original matt, invisible sticky tape with hundreds of uses. Frosty on the roll, invisible when applied. Write on it with pen, pencil or marker.

https://www.3m.co.uk/3M/en_GB/scotch-eu/products/catalog/~/Scotch-Magic-Invisible-Tape-Refill-Pack-1-Roll-19-mm-x-25-m/?N=5002385+8709316+8709380+8710660+8711729+8736246+8736297+3290869391&rt=rud

Categories: Platelet Adhesiveness Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...

https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Platelet+Adhesiveness&parentid=28466&catid=20479

4. Adhesiveness (wanting to develop strong bonds with others, friendship). 5. Combativeness (disposition to fight) ...

https://science.howstuffworks.com/life/inside-the-mind/human-brain/phrenology.htm

pH-responsive injectable hydrogels with mucosal adhesiveness based on chitosan-grafted-dihydrocaffeic acid and oxidized ...

https://www.osti.gov/pages/biblio/1511921-mussel-inspired-hydrogel-composite-multi-stimuli-responsive-behavior

Also regulates extracellular matrix assembly and cell adhesiveness (PubMed:18757743). Promotes endothelial cell survival, ... Also regulates extracellular matrix assembly and cell adhesiveness (PubMed:18757743).. Promotes endothelial cell survival, ...

https://www.uniprot.org/uniprot/Q8C119

Platelet Adhesiveness/drug effects; Serum Albumin/metabolism; Stem Cells/drug effects*; Stem Cells/immunology; Stem Cells/ ...

https://tools.niehs.nih.gov/portfolio/index.cfm?do=portfolio.publicationDetail&id=1677068

Improved adhesiveness as compared to HDG/Z. *Especially suitable for new coating strategies as a result of improved coatability ...

https://www.voestalpine.com/stahl/en/Segments/Automotive

The 50-70-MDa EAF plasmid seems necessary for full expression of pathogenicity in EPEC that exhibit Hep-2 adhesiveness. EPEC ... This result confirmed that class II EPEC are pathogenic by a mechanism not involving Hep-2 adhesiveness. ...

https://pubmed.ncbi.nlm.nih.gov/2863318

Salicylate decreases platelet adhesiveness and interferes with hemostasis in heparin-treated patients. ...

https://dailymed.nlm.nih.gov/dailymed/search.cfm?searchdb=rxcui&query=866892

Platelet Adhesiveness* Actions. * Search in PubMed * Search in MeSH * Add to Search ...

https://www.ncbi.nlm.nih.gov/pubmed/2125373

High, immediate adhesiveness. *Resistant to wash and dry-clean *For many textiles also in combination with leather ...

https://www.uhu.com/en/product-page/textile/63172

기판과의 밀착성Adhesiveness to the substrate 보통usually 양호Good 양호Good 양호Good ... If the content of the additive is less than 1 part by weight, problems may occur in thixotropy, adhesiveness, mold release ...

https://patents.google.com/patent/KR100871060B1/en

Furthermore, in order to further improve the adhesiveness to an oriented film, a small amount of ethylene-acrylate copolymer ( ... Furthermore, in order to further improve the adhesiveness to an oriented film, a small amount of ethylene-acrylate copolymer ( ... If it exceeds 160° C., the thermal adhesiveness cannot be exerted at low temperatures. The average molecular weight exceeding ... If it exceeds 160° C., the thermal adhesiveness cannot be exerted at low temperatures. The average molecular weight exceeding ...

https://www.freepatentsonline.com/y2010/0040942.html

The effect of dipyridamole on platelet aggregation and adhesiveness. (amjmed.com)

Made with 25µ bioriented polypropylene and natural rubber solvent adhesive of high adhesiveness. (coplasem.com)

A high ambient temperature reduces the adhesiveness of the lighting strip. (ikea.com)

Properties influencing collection efficiency include surface texture, adhesiveness, electrostatic properties and other factors. (astm.org)

It has extraordinary adhesiveness and extreme pressure resistance. (whitmores.com)

The product has the Features of good leveling, high coverage, fast dry, rich color and high luster, better flexibility, impact enduring, strong adhesiveness, and match well with many types of paint primers. (aeropaksprays.com)
Strong adhesiveness and waterproof. (utterlyrics.com)

You have to consider a lot of factors such as material, shape, adhesiveness, and size. (radarlogic.com)
More specifically, the invention relates to a laminate shaping support material which is excellent in shape stability, adhesiveness to a model material, peelability and forming stability. (justia.com)

This will cover up any manufacturers' markings and increase the adhesiveness of the surface. (sfgate.com)
Once the surface dries, this compound is applied again to ensure adhesiveness. (drywallsurgeon.com)

Hematologic effects may include prolongation of the prothrombin and bleeding times and decreased platelet adhesiveness. (medscape.com)
Although it is not yet routinely available for clinical use, studies have shown that the plasma, when used at room temperature, appears as a promising innovation featuring antimicrobial activity, positive effects in adhesiveness, tooth whitening and osseointegration, without causing oral tissue damage. (bvsalud.org)

The artist, after numerous experiments, has harnessed this exquisite technique of achieving the exact consistency of paint that gives lasting adhesiveness. (dawn.com)

This model, which describes the adhesiveness of a polymer as a continuous force, does not apply to shellfish proteins and their artificial counterparts. (mpg.de)

Nevertheless, if you're having issues sticking the TENS unit replacement pads you're using right now for whatever reason, here are a few things you can do to improve the adhesiveness of the electrodes. (syrtenty.com)

Aspirin reduces platelet adhesiveness…and may cause some degree of stomach wall erosion with long-term use, so while these risks are low, they are not zero. (medscape.com)
Alpha-granules are the most abundant vesicles in platelets and store proteins that promote platelet adhesiveness and wound healing when secreted during platelet activation. (orpha.net)
This leads to recruitment of leukocytes, increased platelet adhesiveness and activation of the coagulation system, an alteration considered crucial in the pathogenesis of atherosclerotic disease, even in the uninfected subject. (iss.it)
GPS results from the absence or reduction of alpha-granules in platelets, which store proteins that promote platelet adhesiveness and wound healing when secreted during an injury. (nih.gov)
Prothrombotic effects: Nicotine increases platelet adhesiveness by inhibiting prostacyclin, leading to microvascular occlusion and tissue ischemia. (medscape.com)

Promotes matrix assembly and cell adhesiveness (By similarity). (antibodies-online.com)

Combines the of silicone gel sheets utilized in scar therapy with the advantages of self-adhesiveness and durability. (chinavasion.com)

11. Effects of erdosteine and its metabolites on bacterial adhesiveness. (nih.gov)
12. Bacterial adhesiveness: effects of the SH metabolite of erdosteine (mucoactive drug) plus clarithromycin versus clarithromycin alone. (nih.gov)

By forming domains in different states cells my control it adhesiveness, in particular unadhesiveness of endothelial cells for platelets. (nih.gov)
They also eat abundant fish, a major source of eicosapentenoic acid, a protective factor for the cardiovascular system (and of course garlic which reduces the adhesiveness - stickiness - of blood platelets). (healthy.net)

The hardness and adhesiveness of the cooked rice had relation with its water content. (nii.ac.jp)

Virtually colourless and odourless, Contains a biodegradable elasticity and thickening agent that significantly improves its adhesiveness, reducing spattering and consumption. (pellenc.com)

Another important duct tape consideration is tensile strength concerning adhesiveness and thickness - in other words, how well the tape holds and for how long. (my-best.net)

Comfeel was a 'hydrocolloid', a newly developed substance that could absorb liquid without losing flexibility or adhesiveness. (runnersworld.com)
The fabricated device showed unprecedented flexibility, stretchability, and conformal tissue adhesiveness. (sutd.edu.sg)
However, for flexibility, it applies varying formulations for adhesiveness. (bocaratonpaintingcontractor.org)

High Speed Chain is a high adhesiveness lubricant, developed to protect and lubricate all types of chains including the self-lubricating ones (O-Ring). (bardahl.it)
Properties and technology of HIGH SPEED CHAIN Its exclusive BARDAHL POLAR PLUS Formula, together with very high adhesiveness components, enables the lubricant to remain constantly stuck to mechanical parts, thus ensuring an efficient lubrication all the time, much better over traditional lubricants. (bardahl.it)
High adhesiveness to chain links. (bardahl.it)
Surface treatment adhesiveness is high, with superior anti-rust effects for the nuts themselves, as well. (nbk1560.com)
Granular or smooth primer with high adhesiveness. (calcecompany.com)
PTFE-reinforced chain spray with very high adhesiveness. (radne.com)

The in situ forming gel containing 16% of poloxamer and 1.0% of chitosan presented more adequate gelation temperature, mucoadhesive properties, improved mechanical parameters (strength, compressibility and adhesiveness) than both polymers separately and showed to be superior to the polymeric microparticles, with passive permeation flux almost twice higher. (usp.br)

It has snap cuffs that tighten to block out wind, which I prefer because Velcro tends to lose its adhesiveness after a while. (styleforum.net)

It is pressure-sensitive, so the force applied on the tape during installation increases adhesiveness. (my-best.net)

Distinguishing characteristics are adhesiveness, microscopic wave forms, and sub-micron diameter of individual fibers. (carnicominstitute.org)

The present invention provides a curable resin composition that can provide a cured material excellent in insulation reliability while maintaining adhesiveness and provide a composition for forming a solder resist, a dry film and a printed wiring board, a laminate having a resin insulating layer excellent in insulation reliability while maintaining adhesiveness, a dry film for forming this and a process for preparing a laminate using the dry film. (justia.com)
Thus, it is necessary for the resin insulating layer to have sufficient adhesiveness to a substrate regardless of what pretreatment method is applied. (justia.com)
A wide variety of resin compositions having excellent adhesiveness have been known. (justia.com)
This resin is highly effective in imparting gloss, adhesiveness in the inks and also in increasing the solid content in flexo & gravure inks. (polyolsandpolymers.co.in)

We've found the best duct tapes to accommodate your needs, ranging from thin, flexible products to tapes with extreme adhesiveness. (my-best.net)

Lastly, to enhance the adhesiveness of the Galinstan antenna to the moist and soft biological tissues, polydopamine-a mussel-inspired bioadhesive-was used to enhance the adhesion strength to avoid sutures that causes damages to the tissue. (sutd.edu.sg)

To control the cell adhesiveness inside the microchannel, the application of an external stimulus such as ultraviolet (UV) was indispensible. (rsc.org)

This release paper not only prolongs the adhesiveness of the tape but also prevents the gold foil from sticking to the adhesive over time. (navypeony.com)

Over time this can lose its adhesiveness and on my trousers it no longer fastens securely. (trailspace.com)
Electrodes should be replaced periodically, once they lose their adhesiveness. (lsiinternational.com)

The video offers key factors to review, including a project's environment, pace and box type, as well as the tape's grade, quality, shear strength and adhesiveness. (packworld.com)

The possibility of water seepage is reduced by 50%, and the adhesiveness is increased by 100%, so that the edge band and the cabinet body are perfectly fitted. (oppeinhome.com)