Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).Glycogen Storage Disease Type V: Glycogenosis due to muscle phosphorylase deficiency. Characterized by painful cramps following sustained exercise.Diagnostic Errors: Incorrect diagnoses after clinical examination or technical diagnostic procedures.Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.Status Asthmaticus: A sudden intense and continuous aggravation of a state of asthma, marked by dyspnea to the point of exhaustion and collapse and not responding to the usual therapeutic efforts.Depression: Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.Nose: A part of the upper respiratory tract. It contains the organ of SMELL. The term includes the external nose, the nasal cavity, and the PARANASAL SINUSES.Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)Anti-Asthmatic Agents: Drugs that are used to treat asthma.Cellulitis: An acute, diffuse, and suppurative inflammation of loose connective tissue, particularly the deep subcutaneous tissues, and sometimes muscle, which is most commonly seen as a result of infection of a wound, ulcer, or other skin lesions.Flatulence: Production or presence of gas in the gastrointestinal tract which may be expelled through the anus.Institutionalization: The caring for individuals in institutions and their adaptation to routines characteristic of the institutional environment, and/or their loss of adaptation to life outside the institution.Heartburn: Substernal pain or burning sensation, usually associated with regurgitation of gastric juice into the esophagus.Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.Diagnostic Techniques and Procedures: Methods, procedures, and tests performed to diagnose disease, disordered function, or disability.Abbreviations as Topic: Shortened forms of written words or phrases used for brevity.Digestive System: A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS).Review Literature as Topic: Published materials which provide an examination of recent or current literature. Review articles can cover a wide range of subject matter at various levels of completeness and comprehensiveness based on analyses of literature that may include research findings. The review may reflect the state of the art. It also includes reviews as a literary form.Checklist: Aid for consistent recording of data such as tasks completed and observations noted.Digestive System Neoplasms: Tumors or cancer of the DIGESTIVE SYSTEM.Thyroid Gland: A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.Diagnostic Errors: Incorrect diagnoses after clinical examination or technical diagnostic procedures.Pharyngitis: Inflammation of the throat (PHARYNX).Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.Cellulitis: An acute, diffuse, and suppurative inflammation of loose connective tissue, particularly the deep subcutaneous tissues, and sometimes muscle, which is most commonly seen as a result of infection of a wound, ulcer, or other skin lesions.Thyroid Diseases: Pathological processes involving the THYROID GLAND.Thyroid Hormones: Natural hormones secreted by the THYROID GLAND, such as THYROXINE, and their synthetic analogs.Hoarseness: An unnaturally deep or rough quality of voice.Tonsillitis: Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.Penicillin V: A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.Diagnostic Errors: Incorrect diagnoses after clinical examination or technical diagnostic procedures.Respiration Disorders: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.Cellulitis: An acute, diffuse, and suppurative inflammation of loose connective tissue, particularly the deep subcutaneous tissues, and sometimes muscle, which is most commonly seen as a result of infection of a wound, ulcer, or other skin lesions.Respiratory Tract DiseasesRespiratory Sounds: Noises, normal and abnormal, heard on auscultation over any part of the RESPIRATORY TRACT.Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Salivary Glands: Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).
(1/761) Adenoviral gene transfer of the human V2 vasopressin receptor improves contractile force of rat cardiomyocytes.

BACKGROUND: In congestive heart failure, high systemic levels of the hormone arginine vasopressin (AVP) result in vasoconstriction and reduced cardiac contractility. These effects are mediated by the V1 vasopressin receptor (V1R) coupled to phospholipase C beta-isoforms. The V2 vasopressin receptor (V2R), which promotes activation of the Gs/adenylyl cyclase system, is physiologically expressed in the kidney but not in the myocardium. Expression of a recombinant V2R (rV2R) in the myocardium could result in a positive inotropic effect via the endogenous high concentrations of AVP in heart failure. METHODS AND RESULTS: A recombinant adenovirus encoding the human V2R (Ad-V2R) was tested for its ability to modulate the cardiac Gs/adenylyl cyclase system and to potentiate contractile force in rat ventricular cardiomyocytes and in H9c2 cardiomyoblasts. Ad-V2R infection resulted in a virus concentration-dependent expression of the transgene and led to a marked increase in cAMP formation in rV2R-expressing cardiomyocytes after exposure to AVP. Single-cell shortening measurements showed a significant agonist-induced contraction amplitude enhancement, which was blocked by the V2R antagonist, SR 121463A. Pretreatment of Ad-V2R-infected cardiomyocytes with AVP led to desensitization of the rV2R after short-term agonist exposure but did not lead to further loss of receptor function or density after long-term agonist incubation, thus demonstrating resistance of the rV2R to downregulation. CONCLUSIONS: Adenoviral gene transfer of the V2R in cardiomyocytes can modulate the endogenous adenylyl cyclase-signal transduction cascade and can potentiate contraction amplitude in cardiomyocytes. Heterologous expression of cAMP-forming receptors in the myocardium could lead to novel strategies in congestive heart failure by bypassing the desensitized beta-adrenergic receptor signaling.  (+info)

(2/761) A single amino acid in the adenovirus type 37 fiber confers binding to human conjunctival cells.

A 46-kDa receptor, coxsackievirus-adenovirus (Ad) receptor (CAR), mediates cell attachment of a number of different Ad serotypes; however, not all Ad serotypes utilize this receptor for infection. Moreover, the precise amino acid sequences in the Ad fiber protein that mediate cell attachment have yet to be identified. We investigated the interaction of subgroup D Ads with human ocular cells. Ad serotype 37 (Ad37), a virus associated with epidemic keratoconjunctivitis, but not a closely related virus serotype, Ad19p, exhibited preferential binding to and infection of human conjunctival cells. A single amino acid substitution in the Ad19p fiber distal domain (knob), Glu240 to Lys, conferred binding to conjunctival cells, while the reverse substitution in the Ad37 fiber abrogated cell binding. These findings provide new information on the fiber sequences that regulate Ad host cell tropism.  (+info)

(3/761) Detection of adenoviral genome in the myocardium of adult patients with idiopathic left ventricular dysfunction.

BACKGROUND: The use of molecular biological techniques has demonstrated the importance of enteroviral infection of the myocardium in the pathogenesis of myocarditis and dilated cardiomyopathy in adults and adenovirus and enterovirus infection in children. The aim of this study was to determine the frequency of adenoviral infection of the myocardium of adults with impaired left ventricular function of unknown origin. METHODS AND RESULTS: Nested polymerase chain reaction (nPCR) was used to determine the frequency of detection of adenoviral DNA and enteroviral RNA in myocardial tissue samples from 94 adult patients with idiopathic left ventricular dysfunction and 14 control patients. Histological and immunohistological analyses were performed to detect myocardial inflammation. Adenoviral genomic DNA was detected by nPCR in 12 of the 94 patients with left ventricular dysfunction (in each case, adenovirus type 2), whereas enteroviral RNA was detected in another 12 patients. All control samples were negative for both viruses. In all patients, active myocarditis was excluded according to the Dallas criteria. However, there was significantly decreased CD2, CD3, and CD45RO T lymphocyte counts in the adenovirus-positive group compared with the adenovirus-negative group (P<0.05), whereas no differences were associated with enterovirus infection. CONCLUSIONS: Although enteroviruses are an important causative agent in the pathogenesis of myocarditis and dilated cardiomyopathy, this study shows that adenovirus infection is also important in the pathogenesis of left ventricular failure in adults. However, the pathogenetic basis of disease associated with adenovirus infection may be different than that after infection with other agents, particularly with respect to activation of the host immune response.  (+info)

(4/761) Adenovirus infection after pediatric bone marrow transplantation.

Retrospective analysis of 206 patients undergoing 215 consecutive bone marrow transplants (BMT) at St Jude Children's Research Hospital between November 1990 and December 1994 identified 6% (seven male, six female) with adenovirus infection. The affected patients had a median age of 7.9 years (range 3-24 years) at time of transplantation. Although transplants were performed for hematologic malignancies, solid tumors or nonmalignant conditions, only patients with hematologic malignancies had adenoviral infections. Adenovirus was first detected at a median of 54 days (range -4 to +333) after BMT. Adenovirus developed in eight of 69 (11.6%) patients receiving grafts from matched unrelated or mismatched related donors, in four of 52 (7.7%) receiving grafts from HLA-matched siblings, and in one of 93 (1.1%) receiving autografts. The most common manifestation of adenovirus infection was hemorrhagic cystitis, followed by gastroenteritis, pneumonitis and liver failure. The incidence of adenovirus infection in pediatric BMT patients at our institution is similar to that reported in adult patients. Using univariate analysis, use of total body irradiation and type of bone marrow graft were significant risk factors for adenovirus infection. Only use of total body irradiation remained as a factor on multiple logistic regression analysis.  (+info)

(5/761) Lesions and transmission of experimental adenovirus hemorrhagic disease in black-tailed deer fawns.

Adenovirus infection was the cause of an epizootic of hemorrhagic disease that is believed to have killed thousands of mule deer (Odocoileus hemionus) in California during the latter half of 1993. A systemic vasculitis with pulmonary edema and hemorrhagic enteropathy or a localized vasculitis associated with necrotizing stomatitis/pharyngitis/glossitis or osteomyelitis of the jaw were common necropsy findings in animals that died during this epizootic. To study transmission of adenovirus infection in deer and susceptibility of black-tailed deer (Odocoileus hemionus columbianus) fawns to adenovirus infection, six 3-6-month-old black-tailed fawns were divided into two treatment groups. One group was inoculated intravenously and the other group was inoculated through the mucous membranes of the eyes, nose and mouth with purified adenovirus. Each treatment group also included two additional fawns (four total) that were not inoculated but were exposed to inoculated animals (contact animals). One fawn served as a negative control. Between 4 and 16 days postinoculation, 8/10 fawns developed systemic or localized infection with lesions identical to lesions seen in animals with natural disease that died during the epizootic. Transmission was by direct contact, and the route of inoculation did not affect the incubation period or the distribution of the virus (systemic or the localized infection). Immunohistochemical analysis using polyclonal antiserum against bovine adenovirus type 5 demonstrated staining in endothelial cells of vessels in numerous tissues in animals with systemic infection and endothelial staining only in vessels subtending necrotic foci in the upper alimentary tract in animals with the localized form of the disease. All inoculated or exposed animals had staining in the tonsillar epithelium. Transmission electron microscopic examination of lung and ileum from two fawns with pulmonary edema and hemorrhagic enteropathy demonstrated endothelial necrosis and adenovirus virions in endothelial cell nuclei. Adenovirus was reisolated in black-tailed deer pulmonary artery endothelial cells using lung homogenate of the first fawn that developed systemic adenovirus infection. Serum virus neutralization test results suggest that this deer adenovirus is a new serotype.  (+info)

(6/761) Gene transfer to human pancreatic endocrine cells using viral vectors.

We have studied the factors that influence the efficiency of infection of human fetal and adult pancreatic endocrine cells with adenovirus, murine retrovirus, and lentivirus vectors all expressing the green fluorescent protein (Ad-GFP, MLV-GFP, and Lenti-GFP, respectively). Adenoviral but not retroviral vectors efficiently infected intact pancreatic islets and fetal islet-like cell clusters (ICCs) in suspension. When islets and ICCs were plated in monolayer culture, infection efficiency with all three viral vectors increased. Ad-GFP infected 90-95% of the cells, whereas infection with MLV-GFP and Lenti-GFP increased only slightly. Both exposure to hepatocyte growth factor/scatter factor (HGF/SF) and dispersion of the cells by removal from the culture dish and replating had substantial positive effects on the efficiency of infection with retroviral vectors. Studies of virus entry and cell replication revealed that cell dispersion and stimulation by HGF/SF may be acting through both mechanisms to increase the efficiency of retrovirus-mediated gene transfer. Although HGF/SF and cell dispersion increased the efficiency of infection with MLV-GFP, only rare cells with weak staining for insulin were infected, whereas approximately 25% of beta-cells were infected with Lenti-GFP. We conclude that adenovirus is the most potent vector for ex vivo overexpression of foreign genes in adult endocrine pancreatic cells and is the best vector for applications where high-level but transient expression is desired. Under the optimal conditions of cell dispersion plus HGF/SF, infection with MLV and lentiviral vectors is reasonably efficient and stable, but only lentiviral vectors efficiently infect pancreatic beta-cells.  (+info)

(7/761) Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors.

To understand the function of specific proteins in sensory hair cells, it is necessary to add or inactivate those proteins in a system where their physiological effects can be studied. Unfortunately, the usefulness of heterologous expression systems for the study of many hair cell proteins is limited by the inherent difficulty of reconstituting the hair cell's exquisite cytoarchitecture. Expression of exogenous proteins within hair cells themselves may provide an alternative approach. Because recombinant viruses were efficient vectors for gene delivery in other systems, we screened three viral vectors for their ability to express exogenous genes in hair cells of organotypic cultures from mouse auditory and vestibular organs. We observed no expression of the genes for beta-galactosidase or green fluorescent protein (GFP) with either herpes simplex virus or adeno-associated virus. On the other hand, we found robust expression of GFP in hair cells exposed to a recombinant, replication-deficient adenovirus that carried the gene for GFP driven by a cytomegalovirus promoter. Titers of 4 x 10(7) pfu/ml were sufficient for expression in 50% of the approximately 1,000 hair cells in the utricular epithelium; < 1% of the nonhair cells in the epithelium were GFP positive. Expression of GFP was evident as early as 12 h postinfection, was maximal at 4 days, and continued for at least 10 days. Over the first 36 h there was no evidence of toxicity. We recorded normal voltage-dependent and transduction currents from infected cells identified by GFP fluorescence. At longer times hair bundle integrity was compromised despite a cell body that appeared healthy. To assess the ability of adenovirus-mediated gene transfer to alter hair cell function we introduced the gene for the ion channel Kir2.1. We used an adenovirus vector encoding Kir2.1 fused to GFP under the control of an ecdysone promoter. Unlike the diffuse distribution within the cell body we observed with GFP, the ion channel-GFP fusion showed a pattern of fluorescence that was restricted to the cell membrane and a few extranuclear punctate regions. Patch-clamp recordings confirmed the expression of an inward rectifier with a conductance of 43 nS, over an order of magnitude larger than the endogenous inward rectifier. The zero-current potential in infected cells was shifted by -17 mV. These results demonstrate an efficient method for gene transfer into both vestibular and auditory hair cells in culture, which can be used to study the effects of gene products on hair cell function.  (+info)

(8/761) Tracheal aspirate as a substrate for polymerase chain reaction detection of viral genome in childhood pneumonia and myocarditis.

BACKGROUND: Infectious respiratory disorders are important causes of childhood morbidity and mortality. Viral causes are common and may lead to rapid deterioration, requiring mechanical ventilation; myocardial dysfunction may accompany respiratory decompensation. The etiologic viral diagnosis may be difficult with classic methods. The purpose of this study was to evaluate polymerase chain reaction (PCR) as a diagnostic method for identification of causative agents. METHODS AND RESULTS: PCR was used to amplify sequences of viruses known to cause childhood viral pneumonia and myocarditis. Oligonucleotide primers were designed to amplify specific sequences of DNA virus (adenovirus, cytomegalovirus, herpes simplex virus, and Epstein-Barr virus) and RNA virus (enterovirus, respiratory syncytial virus, influenza A, and influenza B) genomes. Tracheal aspirate samples were obtained from 32 intubated patients and nucleic acid extracted before PCR. PCR results were compared with results of culture, serology, and antigen detection methods when available. In cases of myocarditis (n=7), endomyocardial biopsy samples were analyzed by PCR and compared with tracheal aspirate studies. PCR amplification of viral genome occurred in 18 of 32 samples (56%), with 3 samples PCR positive for 2 viral genomes. Amplified viral sequences included RSV (n=3), enterovirus (n=5), cytomegalovirus (n=4), adenovirus (n=3), herpes simplex virus (n=2), Epstein-Barr virus (n=1), influenza A (n=2), and influenza B (n=1). All 7 cases of myocarditis amplified the same viral genome from heart as found by tracheal aspirate. CONCLUSIONS: PCR is a rapid and sensitive diagnostic tool in cases of viral pneumonia with or without myocarditis, and tracheal aspirate appears to be excellent for analysis.  (+info)

*  DNA virus
Family Rudiviridae Unassigned families Family Adenoviridae-includes viruses which cause human adenovirus infection Family ... The families Adenoviridae and Tectiviridae appear to be related structurally. Baculoviruses evolved from the nudiviruses 310 ... Phylogenetic analysis of these genes places the adenoviruses (Adenoviridae), bacteriophages (Caudovirales) and the plant and ... Some have circular genomes (Baculoviridae, Papovaviridae and Polydnaviridae) while others have linear genomes (Adenoviridae, ...
*  Bovine adenovirus
Infection usually results in disease of the gastrointestinal or respiratory tract. Infection may also cause ocular or ... Bovine Adenovirus, also known as BAdV, is a member of the Adenoviridae family that causes disease in cattle. There are 10 ... However, infection may not always result in disease as the virus can be isolated in healthy cattle. Once infected, the cattle ... Signs may worsen if a secondary infection occurs. The classical signs of a generalised disease, such as pyrexia, weight loss, ...
*  Viral envelope
Enveloped viruses can cause persistent infections. Classes of enveloped viruses that contain human pathogens: Herpesviruses ... Adenoviridae Papillomaviridae Picornaviridae Bacterial capsule Cell envelope "CHAPTER #11: VIRUSES". Retrieved 2008-11-07. "The ...
*  Mastadenovirus
usually mild respiratory, gastrointestinal and eye infections. serotypes 3, 5 and 7: lower respiratory tract infections. ... Mastadenovirus is a genus of viruses, in the family Adenoviridae. Human, mammals, and vertebrates serve as natural hosts. There ... very common human infection, estimated to be responsible for between 2% and 5% of all respiratory infections. ... serotype 14: can cause potentially fatal adenovirus infections. Canine adenovirus 1 (CAdV-1) can lead to death in puppies, or ...
*  Baltimore classification
Proper infection and production of progeny requires that the cell be in replication, as it is during replication that the ... Examples include Herpesviridae, Adenoviridae, and Papovaviridae. There is only one well-studied example in which a class 1 ...
*  Porcine adenovirus
Infection is often subclinical, and when clinical signs are seen they are mild and short-lived. Gastrointestinal signs such as ... Porcine adenovirus (aka pADV 1-5 or pADV A-C) is a member of the adenoviridae family. It causes gastrointestinal disease in ... Respiratory signs such as coughing can be seen if the infection is part of a mutlifactorial respiratory disease complex. ... Adenoviridae Bovine adenovirus Porcine Adenovirus, reviewed and published by WikiVet at ...
*  Agamid adenovirus
Even where an Agamid shows no signs of infection, many are believed to be sub-clinically infected, or carriers of the virus. ... Agamid adenovirus (Agamid AdV1) is a type of virus in the Adenoviridae family. The virus is widespread in captive populations ... It is probable that there is a relationship between dose of infection and clinical disease. Coinfections with other agents such ... Agamid Adenovirus is becoming widespread in the United States, with several breeders admitting infection and shutting down ...
*  Adenoviridae
Most infections with adenovirus result in infections of the upper respiratory tract. Adenovirus infections often show up as ... Type 1 infection can also cause respiratory and eye infections. Canine adenovirus 2 (CAdV-2) is one of the potential causes of ... Humans infected with adenoviruses display a wide range of responses, from no symptoms at all to the severe infections typical ... There are no antiviral drugs to treat adenoviral infections, so treatment is largely directed at the symptoms (such as ...
*  Sialic acid
Unsurprisingly, sialic acids also play an important role in several human viral infections. The influenza viruses have ... Many viruses such as some adenoviruses (Adenoviridae), rotaviruses (Reoviridae) and influenza viruses (Orthomyxoviridae) can ...
*  Pathogen
For example, infection of mesenteric lymph glands of mice with Yersinia can clear the way for continuing infection of these ... Pathogenic viruses are diseases mainly of the families of: Adenoviridae, Picornaviridae, Herpesviridae, Hepadnaviridae, ... Infection with many pathogens can be prevented by immunization. A small amount of pathogens are used in vaccines to make ... A class of bacteria without cell walls is mycoplasma (a cause of lung infections). A class of bacteria which must live within ...
*  Human pathogen
... or yeast infections. Most antibiotics that function on bacterial pathogens cannot be used to treat fungal infections because ... Pathogenic viruses are mainly those of the families of: Adenoviridae, Picornaviridae, Herpesviridae, Hepadnaviridae, ... Life-threatening fungal infections in humans most often occur in immunocompromised patients or vulnerable people with a ... Today, while many medical advances have been made to safeguard against infection by pathogens, through the use of vaccination, ...
*  Viral disease
Laboratory investigation may be useful in diagnosing associated bacterial infections, however. Viral infections are commonly of ... There are five double-stranded DNA families: three are non enveloped (Adenoviridae, Papillomaviridae and Polyomaviridae) and ... A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus ... [email protected] List of latent human viral infections Pathogenic bacteria Taylor, M.P.; Kobiler, O.; Enquist, L. W. (2012). " ...
*  DA2PPC vaccine
Treatment is supportive and consists of antibiotics to prevent secondary infections, anticonvulsants for seizures, and ... Animal adenoviridae explained. ...
*  Infectious canine hepatitis
... is an acute liver infection in dogs caused by canine adenovirus type-1 (CAV-1). CAV-1 also causes ... Carter, G.R.; Wise, D.J. (2006). "Adenoviridae". A Concise Review of Veterinary Virology. Retrieved 2006-06-10. Ettinger, ... CAV-2 is one of the causes of respiratory infections in dogs, but it is similar enough to CAV-1 that vaccine for one creates ...
*  Urethritis
It is usually caused by infection with bacteria. The bacterial infection is often sexually transmitted, but not in every ... Other causes include: Adenoviridae Uropathogenic Escherichia coli (UPEC) Herpes simplex Cytomegalovirus Mycoplasma genitalium ... The physician sometimes performs a digital rectal examination to inspect the prostate gland for swelling or infection.[medical ... "Sexually transmitted infections and prostate cancer risk: A systematic review and meta-analysis". Cancer Epidemiology. 38 (4): ...
*  Community-acquired pneumonia
Viral infections weaken the immune system, making the body more susceptible to bacterial infection (including bacterial ... and adenoviridae, mumps and enterovirus can also cause pneumonia. Another cause of CAP in this group is Chlamydia trachomatis, ... Infants can acquire lung infections before birth by breathing infected amniotic fluid or through a blood-borne infection which ... CAP's symptoms are the result of lung infection by microorganisms and the immune system's response to the infection. Mechanisms ...
*  Acute bronchitis
The infection may last from a few to ten days. The cough may persist for several weeks afterward with the total duration of ... In addition, bronchitis caused by Adenoviridae may cause systemic and gastrointestinal symptoms as well. However, the coughs ... Although infection is not the reason or cause of chronic bronchitis, it is seen to aid in sustaining the bronchitis. A physical ... In more than 90% of cases the cause is a viral infection. These viruses may be spread through the air when people cough or by ...
*  Adenovirus E1B protein
Adenoviridae Oncolytic adenovirus Lowe, SW; Ruley, HE (1993). "Stabilization of the p53 tumor suppressor is induced by ... White, E; Cuconati, A (2002). "Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection". Genes & ...
*  Avian adenovirus
Infections are normally subclinical, however clinical disease can occur - especially in young birds as maternal antibody levels ... Group: dsDNA Order: Unassigned Family: Adenoviridae Genus: Aviadenovirus Falcon aviadenovirus A Fowl aviadenovirus A Fowl ... Adenovirus Taxonomy 2005 Diagnosis of Adenovirus Infections in Psittacine Birds by DNA in situ Hybridization Viralzone: ... Adenovirus infection may infect other organs, causing a splenitis, inclusion body hepatitis, bronchitis, pulmonary congestion ...
*  Virus classification
Satellites depend on co-infection of a host cell with a helper virus for productive multiplication. Their nucleic acids have ... Family Adenoviridae (252 capsomeres) Family Papiloviridae (72 capsomeres) Family Paroviridae (32 capsomeres) Family ...
*  Viral replication
It then injects its DNA or RNA into the host to initiate infection. The cell membrane of the host cell invaginates the virus ... An example of a family within this classification is the Adenoviridae There is only one well-studied example in which a class 1 ... Viral replication is the formation of biological viruses during the infection process in the target host cells. Viruses must ...
*  HIV vaccine
... not against infection; HIV infection may remain latent for long periods before causing AIDS.[citation needed] Most effective ... Find an HIV testing site near you Potential HIV vaccine using adenoviridae vectors [1]. ... However, after taking into account the seven people who had HIV infections at the time of their vaccination (two in the placebo ... After three years, the vaccine group saw HIV infection rates reduced by more than 30% compared with those in the placebo group ...
*  Taxonomic list of viruses
Adenoviridae Genus: Atadenovirus Bovine atadenovirus D Duck atadenovirus A Ovine atadenovirus D Possum atadenovirus A Snake ... Viruses portal Virus Virology Virus classification List of latent human viral infections Table of clinically important viruses ...
TACE Plus Recombinant Human Adenovirus for Hepatocellular Carcinoma - Full Text View -  TACE Plus Recombinant Human Adenovirus for Hepatocellular Carcinoma - Full Text View -
DNA Virus Infections. Virus Diseases. Adenoviridae Infections. Carcinoma. Carcinoma, Hepatocellular. Neoplasms, Glandular and ... Any active clinically serious infections (, grade 2 NCI-CTCAE ver 3.0). *HIV infection or AIDS-related illness or serious acute ...
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Cytotoxic T Cells to Prevent Virus Infections - Full Text View -  Cytotoxic T Cells to Prevent Virus Infections - Full Text View -
Infection. Communicable Diseases. Adenoviridae Infections. DNA Virus Infections. Virus Diseases. To Top ... After receiving a cord blood transplant, they are at risk of infections until a new immune system to fight infections grows ... after a viral infection in the post-transplant period. In this study we are trying to prevent or treat viral infections by ... can prevent patients from getting an infection. EBV, AdV and CMV are viruses that can cause serious life-threatening infections ...
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Dacryoadenitis and Runny nose - Symptom Checker - check medical symptoms at RightDiagnosis  Dacryoadenitis and Runny nose - Symptom Checker - check medical symptoms at RightDiagnosis
5. Acute upper respiratory infection. 6. Addiction. 7. Adenoiditis. 8. Adenoviridae Infections. 9. Adenovirus infection in ...
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Black Tea | GreenMedInfo | Substance | Natural Medicine | Alternative  Black Tea | GreenMedInfo | Substance | Natural Medicine | Alternative
Diseases : Adenoviridae Infections. Pharmacological Actions : Antiviral Agents. [+] Black tea extract has the potential to be ... Honey and green/black tea intake is associated with a reduced prevalence of H. pylori infections.Mar 05, 2015. ... Theaflavin digallate has potential to be a promising natural and affordable remedy against herpes simplex viral infections.May ... Gargling with tea and its ingredients may have a preventative effect for influenza infection. Dec 31, 2015. ...
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Serological detection of adenoviruses in non-human primates maintained in a colony in Kenya.  Serological detection of adenoviruses in non-human primates maintained in a colony in Kenya.
These diseases associated with adenovirus infection affect adults and are usually more severe in infant ... Adenoviridae / isolation & purification*. Adenoviridae Infections / veterinary*, virology. Age Distribution. Animals. ... To date, limited studies have been done to determine the prevalence of adenovirus infection in non-human primates with the goal ... CONCLUSION: The results of this study indicate that adenovirus infection is prevalent among non-human primates in Kenya. These ...
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Headache -  Headache -
Adenoviridae Infections ... headache*Adenovirus infection in immunocompromised patients ... headache*Adenovirus-related Cold ... Bartonella infections ... headache*Bartonellosis ... headache*Bartonellosis due to Bartonella quintana infection ... headache* ... Campylobacter jejuni infection ... headache*Campylobacter laridis infection ... headache*Camurati Engelmann disease, type 2 ... Acanthamoeba infection ... headache*Acanthamoeba infection of the central nervous system ... headache*Acanthocheilonemiasis ...
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Digestive symptoms -  Digestive symptoms -
Adenoviridae Infections ... diarrhea, gastroenteritis, gastroenteritis, gastroenteritis, pharyngitis*Adenovirus infection in ... Acanthamoeba infection ... nausea, vomiting, vomiting*Acanthamoeba infection of the central nervous system ... nausea, vomiting ... Arcobacter butzleri infection ... diarrhea, abdominal pain, nausea, vomiting, vomiting*Arcobacter cryaerophilus infection ... ... Campylobacter laridis infection ... diarrhea, abdominal pain, nausea, vomiting, vomiting*Campylobacter sputorum infection ... ...
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Viral Infection | Viral Infection Symptoms | MedlinePlus  Viral Infection | Viral Infection Symptoms | MedlinePlus
Learn more about viral infections and their symptoms. ... Viruses cause familiar infections such as the common cold, but ... Adenoviridae Infections (National Institutes of Health) * Coxsackievirus Infections ( ... Antibiotics do not work for viral infections. There are antiviral medicines to treat some viral infections. Vaccines can help ... Viral Infections: How Do They Differ? (Mayo Foundation for Medical Education and Research) Also in Spanish ...
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Incidence of enteric adenoviruses among children in Thailand and the s by John E. Herrmann, Neil R. Blacklow et al.  "Incidence of enteric adenoviruses among children in Thailand and the s" by John E. Herrmann, Neil R. Blacklow et al.
... differences in the association of bacterial or parasitic infections with either enteric or nonenteric adenovirus infections in ... there were coinfections with rotavirus only in those with nonenteric adenovirus infection (7 of 27 children). There were no ... of those without gastroenteritis were positive for rotavirus infection. In the adenovirus-infected children with ... To determine the incidence of adenovirus infection in a tropical climate, stools were collected from children under age 7 ...
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Sore throat and Swollen thyroid gland - Symptom Checker - check medical symptoms at RightDiagnosis  Sore throat and Swollen thyroid gland - Symptom Checker - check medical symptoms at RightDiagnosis
5. Acute upper respiratory infection. 6. Adenoid disorders. 7. Adenoiditis. 8. Adenoviridae Infections. 9. Adenovirus infection ... Throat infection (13 causes) *Throat rash (10 causes) *more types...» Review causes of types of Sore throat in more specific ...
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William J Muller - Research Output
     - Northwestern Scholars  William J Muller - Research Output - Northwestern Scholars
Laboratory diagnosis of neonatal herpes simplex virus infections. Muller, W. J. & Zheng, X., May 1 2019, In : Journal of ... Treatment of perinatal viral infections to improve neurologic outcomes. Muller, W. J., Jan 1 2017, In : Pediatric Research. 81 ... Immunobiology of herpes simplex virus and cytomegalovirus infections of the fetus and newborn. Muller, W. J., Jones, C. A. & ... Clinical and in vitro evaluation of cidofovir for treatment of adenovirus infection in pediatric hematopoietic stem cell ...
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Jo-Anne H Young - Projects and Grants
     - Experts@Minnesota  Jo-Anne H Young - Projects and Grants - [email protected]
Natural History of Infection Caused by BK Virus (and oth. Young, J. H. ... A Multi-center, Retrospective Study of Serious Infections Caused by Acinetobacter baumanniicalcoaceticusComplex. Young, J. H. ... ElderlyHospitalized Patients With Influenza A Infection. Young, J. H. ... Study to Examine the Efficacy and Safety of DAS181 for theTreatment of Lower Respiratory Tract Parainfluenza Infection in ...
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Find Research Outputs
             - Research Nebraska  Find Research Outputs - Research Nebraska
A 47-year-old woman with nuclear protein in testis midline carcinoma masquerading as a sinus infection: A case report and ... Adolescent perspectives on addressing teenage pregnancy and sexually transmitted infections in the classroom and beyond. Fisher ... Viable Macrophages and Antibiotics Promote Clearance of Staphylococcus aureus Craniotomy-Associated Biofilm Infection. Aldrich ...
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             - 臺北醫學大學  尋找研究成果 - 臺北醫學大學
Multidisciplinary approach in study of the zoonotic Anisakis larval infection in the blue mackerel (Scomber australasicus) and ... Notch ligand-expressing adenovirus infection enhances the efficacy of dendritic cell-based immunotherapy for allergic asthma in ... Immunology and Infection.. 研究成果: 雜誌貢獻 › 文章 ...
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Subject: genes / Publication Year: 2018 / Subject: proteins / Text Availability: Full Text - PubAg Search Results  Subject: 'genes' / Publication Year: 2018 / Subject: proteins / Text Availability: Full Text - PubAg Search Results
gene expression; regulator genes, etc ; Adenoviridae infections; BK polyomavirus; Human adenovirus C; antigens; blood; ... Co-infection with human polyomavirus BK enhances gene expression and replication of human adenovirus ... The aim of the current study was to show that the replication of human adenovirus 5 is enhanced by co-infection with BK p .... ... Thioester‐containing proteins in the tsetse fly (Glossina) and their response to trypanosome infection ...
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臺北醫學大學 - 研究成果
     - 臺北醫學大  臺北醫學大學 - 研究成果 - 臺北醫學大
Tolerability of rifapentine-based regimens in latent tuberculosis infection treatment in the elderly. Chan, P. C., Lee, P. H., ... Notch ligand-expressing adenovirus infection enhances the efficacy of dendritic cell-based immunotherapy for allergic asthma in ... Breakthrough invasive Trichosporon asahii infection in an uremic patient with systemic calciphylaxis complicating necrotizing ... Immunology and Infection. 52, 4, p. 676-678 3 p.. 研究成果: 雜誌貢獻 › 快報 ...
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Publication Year: 2018 / Subject: signs and symptoms (animals and humans) - PubAg Search Results  Publication Year: 2018 / Subject: signs and symptoms (animals and humans) - PubAg Search Results
Adenoviridae infections; Fowl adenovirus A; case studies; chickens; epithelium; farms; feed intake; financial economics; flocks ... Fowl adenovirus infections are widely prevalent in poultry. Many of the viruses can infect chickens without resulting in overt ... 8. Adaptation and evaluation of an ELISA for Trypanosoma evansi infection (surra) in elephants and its application to a ... Adenoviridae; DNA; avirulent strains; bursa of Fabricius; chickens; cross reaction; feathers; flocks; gizzard; hatching; ...
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Nesaranews Natural Homeopathic Healing And GMO Awareness: May 2015  Nesaranews Natural Homeopathic Healing And GMO Awareness: May 2015
Adenoviridae Infections. 4. 4. Adhesions: Abdominal. 2. 1. Adhesive capsulitis. 20. 2. ... Another study showed that copper surfaces in a hospitals killed 97% of the ICU bacteria that can cause infection, which ... resulted in a 40% reduction in infection rates.. Sadhguru, an Indian yogi, mystic, philanthropist said - "If you hold water in ...
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Glomerulonephritis associated with simultaneous canine adenovirus-1 and Dirofilaria immitis infection in a dog.  - Surrey...  Glomerulonephritis associated with simultaneous canine adenovirus-1 and Dirofilaria immitis infection in a dog. - Surrey...
Adenoviridae Infections, Animals, Dirofilariasis, Dog Diseases, Dogs, Glomerulonephritis, Hepatitis, Viral, Animal, ... Glomerulonephritis associated with simultaneous canine adenovirus-1 and Dirofilaria immitis infection in a dog. ... Glomerulonephritis associated with simultaneous canine adenovirus-1 and Dirofilaria immitis infection in a dog. J Vet Med B ...
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Veterinärmedizinische Universität Wien Forschungsinformationssystem VetDoc  Veterinärmedizinische Universität Wien Forschungsinformationssystem VetDoc
Adenoviridae Infections/diagnosis Adenoviridae Infections/immunology Adenoviridae Infections/veterinary* Adenoviridae ... Infections/virology Animals Antibodies, Viral/blood Cell Line Chick Embryo Cloaca/virology Fowl adenovirus A/genetics* Fowl ...
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Search Articles | University of Toronto Libraries  Search Articles | University of Toronto Libraries
adenoviridae infections - diagnosis (1) 1 Filter by. Remove filter. adenovirus infections, human - diagnosis (1) 1 ... Antibody Formation , Respirovirus Infections - immunology , Immunity, Cellular , Pneumonia, Viral - immunology , Humans , ... Eyelid Diseases - drug therapy , Staphylococcal Infections - drug therapy , Double-Blind Method , Gentamicins - therapeutic use ... adenoviridae - isolation & purification (1) 1 Filter by. Remove filter. ...
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  • Adenoviruses (members of the family Adenoviridae) are medium-sized (90-100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA genome. (
  • There are currently 25 species in this genus, including the type species Human mastadenovirus C. Diseases associated with this genus include: very common human infection, estimated to be responsible for between 2% and 5% of all respiratory infections. (
  • in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system. (
  • CAV-2 is one of the causes of respiratory infections in dogs, but it is similar enough to CAV-1 that vaccine for one creates immunity for both. (
  • 2. To compare the incidence of treatment emergent dsDNA viral infections (other than those caused by AdV), in subjects treated with CMX001 QW versus CMX001 BIW versus placebo, initially, for the preemption of adenoviral disease. (
  • A class of bacteria which must live within other cells (obligate intracellular parasitic) is chlamydia (genus), the world leader in causing sexually transmitted infection (STI). (
  • Investigators will test to see if blood cells from donor that have been grown in a special way, can prevent patients from getting an infection. (
  • They have used T cells made in this way from the blood of donors to prevent infections in patients who are getting a bone marrow or blood stem cell transplant but this will be the first time investigators make them from cord blood. (
  • CMV can also cause serious infections in patients with weak or suppressed immune systems. (
  • Life-threatening fungal infections in humans most often occur in immunocompromised patients or vulnerable people with a weakened immune system, although fungi are common problems in the immunocompetent population as the causative agents of skin, nail, or yeast infections. (
  • Other causes include: Adenoviridae Uropathogenic Escherichia coli (UPEC) Herpes simplex Cytomegalovirus Mycoplasma genitalium Reactive arthritis Trichomonas vaginalis Ureaplasma urealyticum Methicillin-resistant Staphylococcus aureus Group B streptococcus In female patients, urethritis can be caused by pelvic inflammatory disease. (
  • A full spectrum of microorganisms is responsible for CAP in adults, and patients with certain risk factors are more susceptible to infections of certain groups of microorganisms. (
  • Some patients have an underlying problem which increases their risk of infection. (
  • Infants can acquire lung infections before birth by breathing infected amniotic fluid or through a blood-borne infection which crossed the placenta. (
  • Work with monoclonal antibodies (MAb) has shown or proven that the human body can defend itself against HIV, and certain individuals remain asymptomatic for decades after HIV infection. (
  • By comparison, 19.7% of children with gastroenteritis and 0.7% of those without gastroenteritis were positive for rotavirus infection. (
  • Pathogenicity is also distinct from the transmissibility of the virus, which quantifies the risk of infection. (
  • And, importantly, HAART does nothing to prevent the spread of HIV by people with undiagnosed infections. (
  • Preventative medications such as antiretroviral treatments have been put into use to help prevent infection, but do not work as well as a vaccine would. (
  • Even where an Agamid shows no signs of infection, many are believed to be sub-clinically infected, or carriers of the virus. (