Virus diseases caused by the ADENOVIRIDAE.
A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS) or both (ATADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases.
A genus of ADENOVIRIDAE that infects birds. The type species is FOWL ADENOVIRUS A.
A genus of ADENOVIRIDAE that comprises viruses of several species of MAMMALS and BIRDS. The type species is Ovine adenovirus D.
A collection of lymphoid nodules on the posterior wall and roof of the NASOPHARYNX.
A genus of ADENOVIRIDAE that infects MAMMALS including humans and causes a wide range of diseases. The type species is Human adenovirus C (see ADENOVIRUSES, HUMAN).
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
A catarrhal disorder of the upper respiratory tract, which may be viral or a mixed infection. It generally involves a runny nose, nasal congestion, and sneezing.
I'm sorry for any confusion, but the term "geese" is a common name for certain species of waterfowl and doesn't have a medical definition. It is not related to medical terminology or healthcare.
Inflammation of the lung parenchyma that is caused by a viral infection.
Infection of the lung often accompanied by inflammation.
Inflammation of the lung parenchyma that is caused by bacterial infections.
Infections with viruses of the family PARAMYXOVIRIDAE. This includes MORBILLIVIRUS INFECTIONS; RESPIROVIRUS INFECTIONS; PNEUMOVIRUS INFECTIONS; HENIPAVIRUS INFECTIONS; AVULAVIRUS INFECTIONS; and RUBULAVIRUS INFECTIONS.
A species of RESPIROVIRUS also called hemadsorption virus 2 (HA2), which causes laryngotracheitis in humans, especially children.
An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.
A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 1 and neuraminidase 1. The H1N1 subtype was responsible for the Spanish flu pandemic of 1918.

Adenoviral gene transfer into the normal and injured spinal cord: enhanced transgene stability by combined administration of temperature-sensitive virus and transient immune blockade. (1/9136)

This study characterized gene transfer into both normal and injured adult rat dorsal spinal cord using first (E1-/E3-) or second (E1-/E2A125/E3-, temperature-sensitive; ts) generation of replication-defective adenoviral (Ad) vectors. A novel immunosuppressive regimen aimed at blocking CD4/CD45 lymphocytic receptors was tested for improving transgene persistence. In addition, the effect of gene transfer on nociception was also evaluated. Seven days after treatment, numerous LacZ-positive cells were observed after transfection with either viral vector. By 21 days after transfection, beta-galactosidase staining was reduced and suggestive of ongoing cytopathology in both Ad-treated groups, despite the fact that the immunogenicity of LacZ/Adts appeared less when compared with that elicited by the LacZ/Ad vector. In contrast, immunosuppressed animals showed a significant (P < or = 0.05) increase in the number of LacZ-positive cells not displaying cytopathology. In these animals, a concomitant reduction in numbers of macrophages/microglia and CD4 and CD8 lymphocytes was observed. Only animals that received LacZ/Adts and immunosuppression showed transgene expression after 60 days. Similar results were observed in animals in which the L4-L5 dorsal roots were lesioned before transfection. Gene transfer into the dorsal spinal cord did not affect nociception, independent of the adenovirus vector. These results indicate that immune blockade of the CD4/CD45 lymphocytic receptors enhanced transgene stability in adult animals with normal or injured spinal cords and that persistent transgene expression in the spinal cord does not interfere with normal neural function.  (+info)

Definition of a major p53 binding site on Ad2E1B58K protein and a possible nuclear localization signal on the Ad12E1B54K protein. (2/9136)

Previous studies have established that adenovirus 2/5 early region 1B (Ad E1B) 58K protein binds p53 strongly and co-localizes with it to cytoplasmic dense bodies whilst the homologous Ad12E1B54K protein binds only weakly and co-localizes primarily to the nucleus in Ad12E1 transformed cells. We have used these properties of the E1B proteins from different viral serotypes to map the p53 binding site on the Ad2/5 protein. A set of chimaeric genes was constructed containing different proportions of the Ad12 and Ad2E1B DNA. These, together with Ad12E1A and E1B19K DNA, were transfected into baby rat kidney cells and transformed lines isolated. From an examination of the properties of these Ad12/Ad2E1B fusion proteins in co-immunoprecipitation and subcellular localization experiments it has been concluded that the p53 binding site on Ad2E1B58K protein lies between amino acids 216 and 235 and that the homologous region on Ad12E1B54K protein also binds p53. In addition, a unique nuclear localization signal is located on Ad12E1B54K between residues 228 and 239. We suggest that primary structure differences in these regions of the Ad2 and Ad12E1B proteins are responsible for the different subcellular localizations in AdE1 transformants.  (+info)

Inducible genetic suppression of neuronal excitability. (3/9136)

Graded, reversible suppression of neuronal excitability represents a logical goal of therapy for epilepsy and intractable pain. To achieve such suppression, we have developed the means to transfer "electrical silencing" genes into neurons with sensitive control of transgene expression. An ecdysone-inducible promoter drives the expression of inwardly rectifying potassium channels in polycistronic adenoviral vectors. Infection of superior cervical ganglion neurons did not affect normal electrical activity but suppressed excitability after the induction of gene expression. These experiments demonstrate the feasibility of controlled ion channel expression after somatic gene transfer into neurons and serve as the prototype for a novel generalizable approach to modulate excitability.  (+info)

Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor. (4/9136)

We have shown previously that human apolipoprotein (apo)C1 transgenic mice exhibit hyperlipidaemia, due primarily to an impaired clearance of very-low-density lipoprotein (VLDL) particles from the circulation. In the absence of at least the low-density-lipoprotein receptor (LDLR), it was shown that APOC1 overexpression in transgenic mice inhibited the hepatic uptake of VLDL via the LDLR-related protein. In the present study, we have now examined the effect of apoC1 on the binding of lipoproteins to both the VLDL receptor (VLDLR) and the LDLR. The binding specificity of the VLDLR and LDLR for apoC1-enriched lipoprotein particles was examined in vivo through adenovirus-mediated gene transfer of the VLDLR and the LDLR [giving rise to adenovirus-containing (Ad)-VLDLR and Ad-LDLR respectively] in APOC1 transgenic mice, LDLR-deficient (LDLR-/-) mice and wild-type mice. Remarkably, Ad-VLDLR treatment did not reduce hyperlipidaemia in transgenic mice overexpressing human APOC1, irrespective of both the level of transgenic expression and the presence of the LDLR, whereas Ad-VLDLR treatment did reverse hyperlipidaemia in LDLR-/- and wild-type mice. On the other hand, Ad-LDLR treatment strongly decreased plasma lipid levels in these APOC1 transgenic mice. These results suggest that apoC1 inhibits the clearance of lipoprotein particles via the VLDLR, but not via the LDLR. This hypothesis is corroborated by in vitro binding studies. Chinese hamster ovary (CHO) cells expressing the VLDLR (CHO-VLDLR) or LDLR (CHO-LDLR) bound less APOC1 transgenic VLDL than wild-type VLDL. Intriguingly, however, enrichment with apoE enhanced dose-dependently the binding of wild-type VLDL to CHO-VLDLR cells (up to 5-fold), whereas apoE did not enhance the binding of APOC1 transgenic VLDL to these cells. In contrast, for binding to CHO-LDLR cells, both wild-type and APOC1 transgenic VLDL were stimulated upon enrichment with apoE. From these studies, we conclude that apoC1 specifically inhibits the apoE-mediated binding of triacylglycerol-rich lipoprotein particles to the VLDLR, whereas apoC1-enriched lipoproteins can still bind to the LDLR. The variability in specificity of these lipoprotein receptors for apoC1-containing lipoprotein particles provides further evidence for a regulatory role of apoC1 in the delivery of lipoprotein constituents to different tissues on which these receptors are located.  (+info)

Adenovirus mediated p53 tumour suppressor gene therapy for human gastric cancer cells in vitro and in vivo. (5/9136)

BACKGROUND/AIMS: Gastric cancer is one of the most prevalent forms of cancer in East Asia. Point mutation of the p53 gene has been reported in more than 60% of cases of gastric cancer and can lead to genetic instability and uncontrolled cell proliferation. The purpose of this investigation was to evaluate the potential of p53 gene therapy for gastric cancer. METHODS: The responses of human gastric cancer cell lines, MKN1, MKN7, MKN28, MKN45, and TMK-1, to recombinant adenoviruses encoding wild type p53 (AdCAp53) were analysed in vitro. The efficacy of the AdCAp53 treatment for MKN1 and MKN45 subcutaneous tumours in nude mice was assessed in vivo. RESULTS: p53-specific growth inhibition was observed in vitro in two of four gastric cancer cell lines with mutated p53, but not in the wild type p53 cell line. The mechanism of the killing of gastric cancer cells by AdCAp53 was found, by flow cytometric analysis and detection of DNA fragmentation, to be apoptosis. In vivo studies showed that the growth of subcutaneous tumours of p53 mutant MKN1 cells was significantly inhibited by direct injection of AdCAp53, but no significant growth inhibition was detected in the growth of p53 wild type MKN45 tumours. CONCLUSIONS: Adenovirus mediated reintroduction of wild type p53 is a potential clinical utility in gene therapy for gastric cancers.  (+info)

Viral gene delivery selectively restores feeding and prevents lethality of dopamine-deficient mice. (6/9136)

Dopamine-deficient mice (DA-/- ), lacking tyrosine hydroxylase (TH) in dopaminergic neurons, become hypoactive and aphagic and die by 4 weeks of age. They are rescued by daily treatment with L-3,4-dihydroxyphenylalanine (L-DOPA); each dose restores dopamine (DA) and feeding for less than 24 hr. Recombinant adeno-associated viruses expressing human TH or GTP cyclohydrolase 1 (GTPCH1) were injected into the striatum of DA-/- mice. Bilateral coinjection of both viruses restored feeding behavior for several months. However, locomotor activity and coordination were partially improved. A virus expressing only TH was less effective, and one expressing GTPCH1 alone was ineffective. TH immunoreactivity and DA were detected in the ventral striatum and adjacent posterior regions of rescued mice, suggesting that these regions mediate a critical DA-dependent aspect of feeding behavior.  (+info)

Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. (7/9136)

Diabetes is a major risk factor for coronary and peripheral artery diseases. Although diabetic patients often present with advanced forms of these diseases, it is not known whether the compensatory mechanisms to vascular ischemia are affected in this condition. Accordingly, we sought to determine whether diabetes could: 1) impair the development of new collateral vessel formation in response to tissue ischemia and 2) inhibit cytokine-induced therapeutic neovascularization. Hindlimb ischemia was created by femoral artery ligation in nonobese diabetic mice (NOD mice, n = 20) and in control C57 mice (n = 20). Hindlimb perfusion was evaluated by serial laser Doppler studies after the surgery. In NOD mice, measurement of the Doppler flow ratio between the ischemic and the normal limb indicated that restoration of perfusion in the ischemic hindlimb was significantly impaired. At day 14 after surgery, Doppler flow ratio in the NOD mice was 0.49+/-0.04 versus 0.73+/-0.06 for the C57 mice (P< or =0.005). This impairment in blood flow recovery persisted throughout the duration of the study with Doppler flow ratio values at day 35 of 0.50+/-0.05 versus 0.90+/-0.07 in the NOD and C57 mice, respectively (P< or =0.001). CD31 immunostaining confirmed the laser Doppler data by showing a significant reduction in capillary density in the NOD mice at 35 days after surgery (302+/-4 capillaries/mm2 versus 782+/-78 in C57 mice (P< or =0.005). The reduction in neovascularization in the NOD mice was the result of a lower level of vascular endothelial growth factor (VEGF) in the ischemic tissues, as assessed by Northern blot, Western blot and immunohistochemistry. The central role of VEGF was confirmed by showing that normal levels of neovascularization (compared with C57) could be achieved in NOD mice that had been supplemented for this growth factor via intramuscular injection of an adenoviral vector encoding for VEGF. We conclude that 1) diabetes impairs endogenous neovascularization of ischemic tissues; 2) the impairment in new blood vessel formation results from reduced expression of VEGF; and 3) cytokine supplementation achieved by intramuscular adeno-VEGF gene transfer restores neovascularization in a mouse model of diabetes.  (+info)

Adenoviral gene transfer of the human V2 vasopressin receptor improves contractile force of rat cardiomyocytes. (8/9136)

BACKGROUND: In congestive heart failure, high systemic levels of the hormone arginine vasopressin (AVP) result in vasoconstriction and reduced cardiac contractility. These effects are mediated by the V1 vasopressin receptor (V1R) coupled to phospholipase C beta-isoforms. The V2 vasopressin receptor (V2R), which promotes activation of the Gs/adenylyl cyclase system, is physiologically expressed in the kidney but not in the myocardium. Expression of a recombinant V2R (rV2R) in the myocardium could result in a positive inotropic effect via the endogenous high concentrations of AVP in heart failure. METHODS AND RESULTS: A recombinant adenovirus encoding the human V2R (Ad-V2R) was tested for its ability to modulate the cardiac Gs/adenylyl cyclase system and to potentiate contractile force in rat ventricular cardiomyocytes and in H9c2 cardiomyoblasts. Ad-V2R infection resulted in a virus concentration-dependent expression of the transgene and led to a marked increase in cAMP formation in rV2R-expressing cardiomyocytes after exposure to AVP. Single-cell shortening measurements showed a significant agonist-induced contraction amplitude enhancement, which was blocked by the V2R antagonist, SR 121463A. Pretreatment of Ad-V2R-infected cardiomyocytes with AVP led to desensitization of the rV2R after short-term agonist exposure but did not lead to further loss of receptor function or density after long-term agonist incubation, thus demonstrating resistance of the rV2R to downregulation. CONCLUSIONS: Adenoviral gene transfer of the V2R in cardiomyocytes can modulate the endogenous adenylyl cyclase-signal transduction cascade and can potentiate contraction amplitude in cardiomyocytes. Heterologous expression of cAMP-forming receptors in the myocardium could lead to novel strategies in congestive heart failure by bypassing the desensitized beta-adrenergic receptor signaling.  (+info)

Adenoviridae infections refer to diseases caused by members of the Adenoviridae family of viruses, which are non-enveloped, double-stranded DNA viruses. These viruses can infect a wide range of hosts, including humans, animals, and birds. In humans, adenovirus infections can cause a variety of symptoms, depending on the specific type of virus and the age and immune status of the infected individual.

Common manifestations of adenovirus infections in humans include:

1. Respiratory illness: Adenoviruses are a common cause of respiratory tract infections, such as bronchitis, pneumonia, and croup. They can also cause conjunctivitis (pink eye) and pharyngoconjunctival fever.
2. Gastrointestinal illness: Some types of adenoviruses can cause diarrhea, vomiting, and abdominal pain, particularly in children and immunocompromised individuals.
3. Genitourinary illness: Adenoviruses have been associated with urinary tract infections, hemorrhagic cystitis, and nephritis.
4. Eye infections: Epidemic keratoconjunctivitis is a severe form of conjunctivitis caused by certain adenovirus types.
5. Central nervous system infections: Adenoviruses have been linked to meningitis, encephalitis, and other neurological disorders, although these are rare.

Transmission of adenoviruses typically occurs through respiratory droplets, contaminated surfaces, or contaminated water. Preventive measures include good hygiene practices, such as handwashing and avoiding close contact with infected individuals. There is no specific treatment for adenovirus infections, but supportive care can help alleviate symptoms. In severe cases or in immunocompromised patients, antiviral therapy may be considered.

Adenoviridae is a family of viruses that includes many species that can cause various types of illnesses in humans and animals. These viruses are non-enveloped, meaning they do not have a lipid membrane, and have an icosahedral symmetry with a diameter of approximately 70-90 nanometers.

The genome of Adenoviridae is composed of double-stranded DNA, which contains linear chromosomes ranging from 26 to 45 kilobases in length. The family is divided into five genera: Mastadenovirus, Aviadenovirus, Atadenovirus, Siadenovirus, and Ichtadenovirus.

Human adenoviruses are classified under the genus Mastadenovirus and can cause a wide range of illnesses, including respiratory infections, conjunctivitis, gastroenteritis, and upper respiratory tract infections. Some serotypes have also been associated with more severe diseases such as hemorrhagic cystitis, hepatitis, and meningoencephalitis.

Adenoviruses are highly contagious and can be transmitted through respiratory droplets, fecal-oral route, or by contact with contaminated surfaces. They can also be spread through contaminated water sources. Infections caused by adenoviruses are usually self-limiting, but severe cases may require hospitalization and supportive care.

An Aviadenovirus is a type of virus that belongs to the family *Adenoviridae* and the genus *Aviadenovirus*. These viruses primarily infect avian species, such as birds, and can cause a variety of diseases. The genome of an Aviadenovirus is double-stranded DNA. Some species of Aviadenoviruses have been known to cause respiratory and reproductive problems in poultry, leading to significant economic losses in the poultry industry. It's important to note that Aviadenoviruses are not known to infect or cause disease in humans.

Atadenovirus is a genus of viruses in the family *Parvoviridae*, which infect a wide range of animals including reptiles, birds, and mammals. These viruses are non-enveloped, meaning they do not have a lipid membrane, and have a single-stranded DNA genome. Atadenoviruses can cause various diseases in their hosts, depending on the specific species of the virus and the animal it infects. Some atadenoviruses have been associated with gastrointestinal illnesses, respiratory infections, and liver disease in animals. However, more research is needed to fully understand the impact of atadenovirus infections in various animal populations.

Adenoids are a pair of masses of lymphoid tissue located in the nasopharynx, which is the upper part of the throat behind the nose. They are part of the immune system and help to protect against infection. Adenoids are largest in children and tend to shrink in size as people get older. In some cases, adenoids can become enlarged or infected, leading to problems such as breathing difficulties, ear infections, and sleep disorders. Treatment for enlarged or infected adenoids may include antibiotics, medications to reduce swelling, or surgical removal of the adenoids (adenoidectomy).

A mastadenovirus is a type of virus that belongs to the family Adenoviridae and the genus Mastadenovirus. These viruses are known to infect mammals, including humans, and can cause a variety of diseases such as respiratory infections, conjunctivitis, and gastroenteritis.

Human mastadenoviruses are typically associated with mild illnesses, although some strains can cause more severe disease, particularly in individuals with weakened immune systems. The virus is usually transmitted through respiratory droplets or contact with contaminated surfaces.

Mastadenoviruses are non-enveloped viruses, which means they do not have a lipid membrane surrounding their protein capsid. They contain a double-stranded DNA genome that encodes for several proteins involved in the virus's replication and assembly. The virus replicates in the nucleus of infected cells and can cause cell lysis or transformation, leading to various clinical manifestations.

Overall, mastadenoviruses are a significant cause of human and animal diseases, and understanding their biology and epidemiology is essential for developing effective prevention and treatment strategies.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

The common cold is a viral infectious disease of the upper respiratory tract. It primarily affects the nose, throat, sinuses, and upper airways. The main symptoms include sore throat, runny or stuffy nose, sneezing, cough, and fatigue. The common cold is often caused by rhinoviruses and can also be caused by other viruses like coronaviruses, coxsackieviruses, and adenoviruses. It is usually spread through respiratory droplets when an infected person coughs, sneezes, or talks. The common cold is self-limiting and typically resolves within 7-10 days, although some symptoms may last up to three weeks. There is no specific treatment for the common cold, and management focuses on relieving symptoms with over-the-counter medications, rest, and hydration. Preventive measures include frequent hand washing, avoiding close contact with sick individuals, and not touching the face with unwashed hands.

I'm sorry for any confusion, but "geese" is not a medical term. It refers to various waterbirds constituting the family Anatidae and the genus Branta, characterized by a long neck, wide wings, and a honking call. They are not related to human health or medicine. If you have any medical concerns or questions, I'd be happy to help you with those!

Viral pneumonia is a type of pneumonia caused by viral infection. It primarily affects the upper and lower respiratory tract, leading to inflammation of the alveoli (air sacs) in the lungs. This results in symptoms such as cough, difficulty breathing, fever, fatigue, and chest pain. Common viruses that can cause pneumonia include influenza virus, respiratory syncytial virus (RSV), and adenovirus. Viral pneumonia is often milder than bacterial pneumonia but can still be serious, especially in young children, older adults, and people with weakened immune systems. Treatment typically involves supportive care, such as rest, hydration, and fever reduction, while the body fights off the virus. In some cases, antiviral medications may be used to help manage symptoms and prevent complications.

Pneumonia is an infection or inflammation of the alveoli (tiny air sacs) in one or both lungs. It's often caused by bacteria, viruses, or fungi. Accumulated pus and fluid in these air sacs make it difficult to breathe, which can lead to coughing, chest pain, fever, and difficulty breathing. The severity of symptoms can vary from mild to life-threatening, depending on the underlying cause, the patient's overall health, and age. Pneumonia is typically diagnosed through a combination of physical examination, medical history, and diagnostic tests such as chest X-rays or blood tests. Treatment usually involves antibiotics for bacterial pneumonia, antivirals for viral pneumonia, and supportive care like oxygen therapy, hydration, and rest.

Bacterial pneumonia is a type of lung infection that's caused by bacteria. It can affect people of any age, but it's more common in older adults, young children, and people with certain health conditions or weakened immune systems. The symptoms of bacterial pneumonia can vary, but they often include cough, chest pain, fever, chills, and difficulty breathing.

The most common type of bacteria that causes pneumonia is Streptococcus pneumoniae (pneumococcus). Other types of bacteria that can cause pneumonia include Haemophilus influenzae, Staphylococcus aureus, and Mycoplasma pneumoniae.

Bacterial pneumonia is usually treated with antibiotics, which are medications that kill bacteria. The specific type of antibiotic used will depend on the type of bacteria causing the infection. It's important to take all of the prescribed medication as directed, even if you start feeling better, to ensure that the infection is completely cleared and to prevent the development of antibiotic resistance.

In severe cases of bacterial pneumonia, hospitalization may be necessary for close monitoring and treatment with intravenous antibiotics and other supportive care.

Paramyxoviridae is a family of viruses that includes several important pathogens causing respiratory infections in humans and animals. According to the medical perspective, Paramyxoviridae infections refer to the diseases caused by these viruses.

Some notable human paramyxovirus infections include:

1. Respiratory Syncytial Virus (RSV) Infection: RSV is a common cause of respiratory tract infections, particularly in young children and older adults. It can lead to bronchiolitis and pneumonia, especially in infants and patients with compromised immune systems.
2. Measles (Rubeola): Measles is a highly contagious viral disease characterized by fever, cough, coryza (runny nose), conjunctivitis, and a maculopapular rash. It can lead to severe complications such as pneumonia, encephalitis, and even death, particularly in malnourished children and individuals with weakened immune systems.
3. Parainfluenza Virus Infection: Parainfluenza viruses are responsible for upper and lower respiratory tract infections, including croup, bronchitis, and pneumonia. They mainly affect young children but can also infect adults, causing mild to severe illnesses.
4. Mumps: Mumps is a contagious viral infection that primarily affects the salivary glands, causing painful swelling. It can lead to complications such as meningitis, encephalitis, deafness, and orchitis (inflammation of the testicles) in rare cases.
5. Human Metapneumovirus (HMPV) Infection: HMPV is a respiratory virus that can cause upper and lower respiratory tract infections, similar to RSV and parainfluenza viruses. It mainly affects young children and older adults, leading to bronchitis, pneumonia, and exacerbations of chronic lung diseases.

Prevention strategies for Paramyxoviridae infections include vaccination programs, practicing good personal hygiene, and implementing infection control measures in healthcare settings.

Parainfluenza Virus 1, Human (HPIV-1) is a type of respiratory virus that belongs to the family Paramyxoviridae and genus Respirovirus. It is one of the four serotypes of human parainfluenza viruses (HPIVs), which are important causes of acute respiratory infections in children, immunocompromised individuals, and the elderly.

HPIV-1 primarily infects the upper respiratory tract, causing symptoms such as cough, runny nose, sore throat, and fever. However, it can also cause lower respiratory tract infections, including bronchitis, bronchiolitis, and pneumonia, particularly in young children and infants.

HPIV-1 is transmitted through respiratory droplets or direct contact with infected individuals. The incubation period for HPIV-1 infection ranges from 2 to 7 days, after which symptoms can last for up to 10 days. There is no specific antiviral treatment available for HPIV-1 infections, and management typically involves supportive care such as hydration, fever reduction, and respiratory support if necessary.

Prevention measures include good hand hygiene, avoiding close contact with infected individuals, and practicing cough etiquette. Vaccines are not currently available for HPIV-1 infections, but research is ongoing to develop effective vaccines against these viruses.

Influenza, also known as the flu, is a highly contagious viral infection that attacks the respiratory system of humans. It is caused by influenza viruses A, B, or C and is characterized by the sudden onset of fever, chills, headache, muscle pain, sore throat, cough, runny nose, and fatigue. Influenza can lead to complications such as pneumonia, bronchitis, and ear infections, and can be particularly dangerous for young children, older adults, pregnant women, and people with weakened immune systems or chronic medical conditions. The virus is spread through respiratory droplets produced when an infected person coughs, sneezes, or talks, and can also survive on surfaces for a period of time. Influenza viruses are constantly changing, which makes it necessary to get vaccinated annually to protect against the most recent and prevalent strains.

'Influenza A Virus, H1N1 Subtype' is a specific subtype of the influenza A virus that causes flu in humans and animals. It contains certain proteins called hemagglutinin (H) and neuraminidase (N) on its surface, with this subtype specifically having H1 and N1 antigens. The H1N1 strain is well-known for causing the 2009 swine flu pandemic, which was a global outbreak of flu that resulted in significant morbidity and mortality. This subtype can also cause seasonal flu, although the severity and symptoms may vary. It is important to note that influenza viruses are constantly changing, and new strains or subtypes can emerge over time, requiring regular updates to vaccines to protect against them.

Adenoviruses (members of the family Adenoviridae) are medium-sized (90-100 nm), nonenveloped (without an outer lipid bilayer) ... Wikimedia Commons has media related to Adenoviridae. Portals: Medicine Viruses (Articles with short description, Short ... Harrach B, Benkő M (2021). "Adenoviruses (Adenoviridae)". Encyclopedia of Virology. Vol. 2. Elsevier. ISBN 9780128145166. ...
Carter, G.R.; Wise, D.J. (2006). "Adenoviridae". A Concise Review of Veterinary Virology. Retrieved 2006-06-10. Ettinger, ...
Viral nonstructural proteins, Adenoviridae). ...
Her research is in the field of human Adenoviridae. During her career at Cold Spring Harbor Laboratory she has edited more than ...
... is a genus of viruses, in the family Adenoviridae. Vertebrates serve as natural hosts. There are 10 species in ...
... is a genus of viruses in the family Adenoviridae. Humans and other mammals serve as natural hosts. There are 51 ...
... is a genus of viruses, in the family Adenoviridae. Fish serve as natural hosts. There is only one species in ...
... is a genus of viruses, in the family Adenoviridae. Vertebrates serve as natural hosts. There are eight species in ...
An example of a family within this classification is the Adenoviridae. There is only one well-studied example in which a class ...
ChAdOx1 is a weakened version of chimpanzee adenoviridae (the common cold virus). Specifically, Rollier and co-workers added ...
DNA-based viral vectors include Adenoviridae, adeno-associated virus and herpes simplex virus. Several of the methods used to ...
... , formerly Bat adenovirus TJM, is a species of the genus Mastadenovirus of the family Adenoviridae. It is a ... Adenovirus genome Davison, Andrew (19 June 2013). "Change all species names in the family Adenoviridae to incorporate a genus ... family Adenoviridae" (PDF). International Committee on Taxonomy of Viruses (ICTV). Retrieved 12 February 2019. In 2010, Li Y. ... Adenoviridae". International Committee on Taxonomy of Viruses (ICTV). 2011. Retrieved 12 February 2019. List of other related ...
2018 disasters in the United States, 2018 disease outbreaks, Adenoviridae, Disease outbreaks in the United States). ...
... (aka pADV 1-5 or pADV A-C) is a virus in the family Adenoviridae. It causes mild gastrointestinal diseases ... Adenoviridae, All stub articles, Veterinary medicine stubs). ...
Five of the human DNA viral families have multiple kinetic classes: Poxviridae, Herpesviridae, Adenoviridae, Papillomaviridae, ...
... , also known as BAdV, is a member of the Adenoviridae family that causes disease in cattle. There are 10 ...
... and adenoviridae, mumps and enterovirus can also cause pneumonia. Another cause of neonatal CAP is Chlamydia trachomatis, which ...
... (Agamid AdV1), also called Bearded dragon adenovirus 1, is a type of virus in the Adenoviridae family. The ...
Adenoviridae, Genomics, Animal virology). ...
... is related to bacterial virus families Tectiviridae and Corticoviridae and many eukaryotic virus families such as Adenoviridae ...
Adenoviridae, Papillomaviridae and Polyomaviridae) and two are enveloped (Herpesviridae and Poxviridae). All of the non- ...
... belongs to the Adenoviridae family, and along with human adenovirus 40, is a member of species human ...
Adenoviridae, Bird diseases, Falcons). ...
This use of the term penton appears in the article on Adenoviridae in the description of the capsid of this family of viruses.[ ...
Pathogenic viruses are mainly those of the families of: Adenoviridae, Picornaviridae, Herpesviridae, Hepadnaviridae, ...
Examples of MR in animal viruses are described in the articles Herpes simplex virus, Influenza A virus, Adenoviridae, Simian ...
Many viruses such as the Ad26 serotype of adenoviruses (Adenoviridae), rotaviruses (Reoviridae) and influenza viruses ( ...
Adenoviridae, Experimental cancer treatments, Orphan drugs, Virotherapy, Experimental drugs, All stub articles, Antineoplastic ...
Adenoviridae, Chinese COVID-19 vaccines, Products introduced in 2020, Viral vector vaccines). ...
Adenoviruses (members of the family Adenoviridae) are medium-sized (90-100 nm), nonenveloped (without an outer lipid bilayer) ... Wikimedia Commons has media related to Adenoviridae. Portals: Medicine Viruses (Articles with short description, Short ... Harrach B, Benkő M (2021). "Adenoviruses (Adenoviridae)". Encyclopedia of Virology. Vol. 2. Elsevier. ISBN 9780128145166. ...
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Varidnaviria / Bamfordvirae / Preplasmiviricota / Tectiliviricetes / Rowavirales / Adenoviridae / Mastadenovirus / Canine ... Varidnaviria / Bamfordvirae / Preplasmiviricota / Tectiliviricetes / Rowavirales / Adenoviridae / Mastadenovirus / Human ... Varidnaviria / Bamfordvirae / Preplasmiviricota / Tectiliviricetes / Rowavirales / Adenoviridae / Mastadenovirus / Human ... Varidnaviria / Bamfordvirae / Preplasmiviricota / Tectiliviricetes / Rowavirales / Adenoviridae / Mastadenovirus / Bovine ...
Varidnaviria / Bamfordvirae / Preplasmiviricota / Tectiliviricetes / Rowavirales / Adenoviridae / Mastadenovirus / Canine ... Varidnaviria / Bamfordvirae / Preplasmiviricota / Tectiliviricetes / Rowavirales / Adenoviridae / Mastadenovirus / Human ... Varidnaviria / Bamfordvirae / Preplasmiviricota / Tectiliviricetes / Rowavirales / Adenoviridae / Mastadenovirus / Human ... Varidnaviria / Bamfordvirae / Preplasmiviricota / Tectiliviricetes / Rowavirales / Adenoviridae / Mastadenovirus / Bovine ...
"Adenoviridae Infections" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Adenoviridae Infections" by people in this website by year, ... Below are the most recent publications written about "Adenoviridae Infections" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Adenoviridae Infections". ...
The Adenoviridae U exon protein family has 0 members , canSARS ...
Adenoviridae / genetics* * Animals * Cardiomyopathies / genetics * Cardiomyopathies / metabolism * Cardiomyopathies / therapy* ...
Adenoviridae: the viruses and their replication. In: Knipe DM, Howley PM, editors. Fields virology, 5th ed. Philadelphia: ...
Adenoviridae (adenoviruses). * Coronaviridae (coronaviruses) - Middle East respiratory syndrome coronavirus (MERS-CoV), severe ...
Adenoviridae / genetics* * Animals * Bradykinin / pharmacology * Calcium * Cardiomyopathies / therapy * Coronary Circulation / ...
Adenoviridae ( adenoviruses) * Coronaviridae (coronaviruses) - SARS, MERS, 2019 novel coronavirus (2019-nCoV) [14] ...
Adenoviridae genomes.jpg 482 × 180; 20 KB. * Alphasatellite genome.png 266 × 230; 13 KB. ...
Familia: Adenoviridae Genera: Atadenovirus - Aviadenovirus - Ichtadenovirus - Mastadenovirus - Siadenovirus. Familia: ...
ICTV Virus Taxonomy Profile: Adenoviridae 2022 Journal of General Virology, Microbiology Society 2022, Vol. 103, (3) ...
Categories: Adenoviridae Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 10 ...
Adenoviridae. MeSH term: ... that overexpression of the E2F1 complementary DNA can activate DNA synthesis in cells that would ...
Adenoviridae, Adenoviridae Infections, Bacterial Adhesion, Capsid, Capsid Proteins, Cells, Cultured, Cytarabine, Epithelium, ... Adenoviridae; Adenoviridae Infections; Bacterial Adhesion; Capsid; Capsid Proteins; Cells, Cultured; Cytarabine; Epithelium; ...
Adenoviridae. Mastadenovirus. T40337. Human adenovirus A (Human mastadenovirus A). H00371. T40100. Human adenovirus B (Human ...
ONeill, K. M., Campbell, D. C., Edgar, K. S., Gill, E. K., Moez, A., McLoughlin, K. J., ONeill, C. L., Dellett, M., Hargey, C. J., Abudalo, R. A., OHare, M., Doyle, P., Toh, T., Khoo, J., Wong, J., McCrudden, C. M., Meloni, M., Brunssen, C., Morawietz, H., Yoder, M. C., & 6 othersMcDonald, D. M., Watson, C. J., Stitt, A. W., Margariti, A., Medina, R. J. & Grieve, D. J., 01 Feb 2020, In: Cardiovascular Research. 116, 2, p. 393-405 13 p.. Research output: Contribution to journal › Article › peer-review ...
Human Advs are nonenveloped double-stranded DNA viruses and belong to the Adenoviridae family [7, 8]. Human Advs are divided ...
Adenoviridae, and Partitiviridae, as well as different unclassified viruses. We further characterized three near full-length ... Adenoviridae, and Partitiviridae, as well as different unclassified viruses. We further characterized three near full-length ...
The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, and host nucleic acid composition can each have a profound effect on signal distribution. Exploratory analysis of fluorescent signal distribution in clinical samples has revealed deviations from normality, suggesting that distribution-free approaches should be applied. Positive predictive value and false positive rates were examined to assess the utility of three well-established nonparametric methods for the analysis of viral array hybridization data: (1) Mann-Whitney U, (2) the Spearman correlation coefficient and (3) the chi-square test. Of the three tests, the chi-square proved most useful. The acceptance of microarray use for routine clinical diagnostics will require that the technology be accompanied by simple yet reliable analytic methods. We report that our implementation of the chi-square test yielded a combination of low false
Adenoviridae, Picornaviridae, Herpesviridae, Hepadnaviridae, Flaviviridae, Retroviridae, Orthomyxoviridae, Paramyxoviridae, ...
Adenoviridae encompasses more than 300 different vertebrate-infecting types, including seven human AdV (HAdV) species (A to G) ...
Adenoviridae (MeSH) * Antigens, Viral (MeSH) * Ataxia Telangiectasia (MeSH) * Bloom Syndrome (MeSH) * DNA Repair (MeSH) ...
Veterinary microbiology and microbial diseases Second Edition P.J. Quinn ...
ADENOVIRIDAE FAMILY September 7, 2023. HEPADNAVIRIDAE FAMILY September 7, 2023. POLYOMAVIRIDAE FAMILY July 19, 2023. ...
Sparano, J. A., Gray, R. J., Makower, D. F., Pritchard, K. I., Albain, K. S., Hayes, D. F., Geyer, C. E., Dees, E. C., Perez, E. A., Olson, J. A., Zujewski, J. A., Lively, T., Badve, S. S., Saphner, T. J., Wagner, L. I., Whelan, T. J., Ellis, M. J., Paik, S., Wood, W. C., Ravdin, P., & 11 othersKeane, M. M., Gomez Moreno, H. L., Reddy, P. S., Goggins, T. F., Mayer, I. A., Brufsky, A. M., Toppmeyer, D. L., Kaklamani, V. G., Atkins, J. N., Berenberg, J. L. & Sledge, G. W., Nov 19 2015, In: New England Journal of Medicine. 373, 21, p. 2005-2014 10 p.. Research output: Contribution to journal › Article › peer-review ...
  • We are talking about Adenovirus of the family Adenoviridae. (com.bd)
  • Adenovirus belongs to the wider Adenoviridae family. (com.bd)
  • Adenoviruses (members of the family Adenoviridae) are medium-sized (90-100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. (wikipedia.org)
  • Adenoviridae Infections" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • This graph shows the total number of publications written about "Adenoviridae Infections" by people in this website by year, and whether "Adenoviridae Infections" was a major or minor topic of these publications. (ucdenver.edu)
  • Below are the most recent publications written about "Adenoviridae Infections" by people in Profiles. (ucdenver.edu)
  • Human Advs are nonenveloped double-stranded DNA viruses and belong to the Adenoviridae family [ 7 , 8 ]. (hindawi.com)
  • Vaccines used to prevent infection by any virus from the family ADENOVIRIDAE. (bvsalud.org)
  • Epidemic keratoconjunctivitis (EKC) is a severe disease of the eye, caused by members of the Adenoviridae (Ad) family, with symptoms such as keratitis, conjunctivitis, pain, edema, and reduced vision that may last for months or years. (lu.se)
  • Vacunas utilizadas para prevenir infecciones de cualquier virus de la familia ADENOVIRIDAE. (bvsalud.org)
  • Virus diseases caused by the ADENOVIRIDAE. (ucdenver.edu)
  • Detta steg är nödvändigt för att virus ska kunna föröka sig i en infekterad cell och sprida sig vidare till intilliggande celler och vidare till andra människor. (umu.se)
  • Flaviviridae, Adenoviridae, Alphaherpesvirinae Rhabdoviridae). (nih.gov)
  • Virus diseases caused by the ADENOVIRIDAE . (nih.gov)