A benign epithelial tumor with a glandular organization.
A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)
An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)
Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
A benign neoplasm of the ADRENAL CORTEX. It is characterized by a well-defined nodular lesion, usually less than 2.5 cm. Most adrenocortical adenomas are nonfunctional. The functional ones are yellow and contain LIPIDS. Depending on the cell type or cortical zone involved, they may produce ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE.
A benign epithelial tumor of the LIVER.
A benign tumor of the anterior pituitary in which the cells do not stain with acidic or basic dyes.
A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH HORMONE leads to ACROMEGALY.
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.
A pituitary adenoma which secretes ADRENOCORTICOTROPIN, leading to CUSHING DISEASE.
A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)
Endoscopic examination, therapy or surgery of the luminal surface of the colon.
Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)
A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA.
A small tumor of the anterior lobe of the pituitary gland whose cells stain with basic dyes. It may give rise to excessive secretion of ACTH, resulting in CUSHING SYNDROME. (Dorland, 27th ed)
Tumors or cancers of the ADRENAL CORTEX.
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.
A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
Tumors or cancer of the SALIVARY GLANDS.
Tumors or cancer of the COLON.
Tumors or cancer of the INTESTINES.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Tumors or cancer of the ADRENAL GLANDS.
A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.
Tumors or cancer of the PAROTID GLAND.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA.
An irregular unpaired bone situated at the SKULL BASE and wedged between the frontal, temporal, and occipital bones (FRONTAL BONE; TEMPORAL BONE; OCCIPITAL BONE). Sphenoid bone consists of a median body and three pairs of processes resembling a bat with spread wings. The body is hollowed out in its inferior to form two large cavities (SPHENOID SINUS).
Tumors or cancer of the DUODENUM.
An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).
A small, unpaired gland situated in the SELLA TURCICA. It is connected to the HYPOTHALAMUS by a short stalk which is called the INFUNDIBULUM.
A malignant epithelial tumor with a glandular organization.
A condition of abnormally elevated output of PARATHYROID HORMONE due to parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. It is characterized by the combination of HYPERCALCEMIA, phosphaturia, elevated renal 1,25-DIHYDROXYVITAMIN D3 synthesis, and increased BONE RESORPTION.
Tumors or cancer of the THYROID GLAND.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
A bony prominence situated on the upper surface of the body of the sphenoid bone. It houses the PITUITARY GLAND.
Endoscopic examination, therapy or surgery of the sigmoid flexure.
A mass of histologically normal tissue present in an abnormal location.
Tumors or cancer of the RECTUM.
The sudden loss of blood supply to the PITUITARY GLAND, leading to tissue NECROSIS and loss of function (PANHYPOPITUITARISM). The most common cause is hemorrhage or INFARCTION of a PITUITARY ADENOMA. It can also result from acute hemorrhage into SELLA TURCICA due to HEAD TRAUMA; INTRACRANIAL HYPERTENSION; or other acute effects of central nervous system hemorrhage. Clinical signs include severe HEADACHE; HYPOTENSION; bilateral visual disturbances; UNCONSCIOUSNESS; and COMA.
A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.
The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
Hormones secreted by the PITUITARY GLAND including those from the anterior lobe (adenohypophysis), the posterior lobe (neurohypophysis), and the ill-defined intermediate lobe. Structurally, they include small peptides, proteins, and glycoproteins. They are under the regulation of neural signals (NEUROTRANSMITTERS) or neuroendocrine signals (HYPOTHALAMIC HORMONES) from the hypothalamus as well as feedback from their targets such as ADRENAL CORTEX HORMONES; ANDROGENS; ESTROGENS.
A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.
Excision of one or more of the parathyroid glands.
Antineoplastic agent that is also used as a veterinary anesthetic. It has also been used as an intermediate in organic synthesis. Urethane is suspected to be a carcinogen.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
A benign tumor of the intrahepatic bile ducts.
A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.
The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON.

Salivary gland tumors in Jordan: a retrospective study of 221 patients. (1/197)

AIM: To evaluate the types and clinical outcome of salivary gland tumors in Jordan. METHODS: Hospital records of 221 patients (85 women and 136 men) with salivary gland tumors, diagnosed from January 1988 to December 1997 were reviewed. The patients were analyzed according to sex, age, histopathological type and site of the tumor. Survival curves for patients with malignant tumors were constructed using Kaplan-Meier's method. RESULTS: Of the total 221 salivary gland tumors, 155 (70.2%) were parotid tumors, 42 (19%) minor salivary gland tumors, 23 (10.4%) submandibular gland tumors, and a single (0.4%) sublingual gland tumor. Most of the tumors (151, or 68.4%) were classified as benign and 70 (31.6%) were malignant. Men to women ratio was 1.6:1, and the age of the patients ranged from 2 to 81 years. The overall 5 and 10 year-survival rates for the 70 malignant tumors were 67% and 53%, respectively, for all tumor stages. Mucoepidermoid carcinoma had the best, and squamous cell carcinoma the worst 10-year survival rate. Patients treated with surgery and subsequent radiation therapy had better survival rates than those treated with surgery or radiation therapy alone. CONCLUSION: The principal site for salivary gland tumors in Jordan population was the parotid, and the pleo- morphic adenoma the most common pathological finding. Tumor characteristics and survival data for the Jordanian population are comparable to those from western countries.  (+info)

Clinically benign parotid tumours: local dissection as an alternative to superficial parotidectomy in selected cases. (2/197)

In a personal series of 162 tumours, 101 were pleomorphic adenomas 28 of which were removed by elective local extra capsular dissection and 73 by a conventional nerve dissection. There were no recurrences in either group after a mean follow-up 10.3 years, range 3-21 years for local dissection and 8.3 years, range 3-22 years for nerve dissection. Frey's syndrome did not occur after local dissection but was present in 25% of patients after a nerve dissection. Of the 162 parotid lumps, 17 proved to be a carcinoma but only one was deemed suitable for a local removal, a low grade muco epidermoid carcinoma of the accessory lobe and no recurrence has occurred after 8 years. In benign disease, local dissection gives similar results to conventional nerve dissection with less morbidity and confirms that tumour recurrence cannot be ascribed to any properties of the tumour but lies in the hands of the surgeon and depends on the care with which the tumour is removed.  (+info)

PLAG1, the main translocation target in pleomorphic adenoma of the salivary glands, is a positive regulator of IGF-II. (3/197)

PLAG1, a novel developmentally regulated C2H2 zinc finger gene, is consistently rearranged and overexpressed in pleomorphic adenomas of the salivary glands with 8q12 translocations. In this report, we show that PLAG1 is a nuclear protein that binds DNA in a specific manner. The consensus PLAG1 binding site is a bipartite element containing a core sequence, GRGGC, and a G-cluster, RGGK, separated by seven random nucleotides. DNA binding is mediated mainly via three of the seven zinc fingers, with fingers 6 and 7 interacting with the core and finger 3 with the G-cluster. In transient transactivation assays, PLAG1 specifically activates transcription from its consensus DNA binding site, indicating that PLAG1 is a genuine transcription factor. Potential PLAG1 binding sites were found in the promoter 3 of the human insulin-like growth factor II (IGF-II) gene. We show that PLAG1 binds IGF-II promoter 3 and stimulates its activity. Moreover, IGF-II transcripts derived from the P3 promoter are highly expressed in salivary gland adenomas overexpressing PLAG1. In contrast, they are not detectable in adenomas without abnormal PLAG1 expression nor in normal salivary gland tissue. This indicates a perfect correlation between PLAG1 and IGF-II expression. All of these results strongly suggest that IGF-II is one of the PLAG1 target genes, providing us with the first clue for understanding the role of PLAG1 in salivary gland tumor development.  (+info)

Cartilage-specific matrix protein chondromodulin-I is associated with chondroid formation in salivary pleomorphic adenomas: immunohistochemical analysis. (4/197)

Chondromodulin-I (ChM-I) is a novel cartilage-specific matrix protein. In the growth plates of the long bones, ChM-I was shown to be expressed in mature to upper hypertrophic chondrocytes, and to be deposited in the cartilage matrix. As ChM-I strongly inhibits angiogenesis, cartilage is avascular. Also, ChM-I has bifunctional activity against chondrocyte proliferation. On the other hand, pleomorphic adenomas of the salivary glands frequently have chondroid elements. To elucidate the relationship between chondroid formation and hypovascularity in salivary pleomorphic adenomas, we immunohistochemically examined the expression and localization of ChM-I in 35 cases of this tumor. ChM-I was immunolocalized to the lacunae in the chondroid elements of pleomorphic adenomas (100%). Type II collagen and aggrecan were immunolocalized throughout the matrix around lacuna cells of the chondroid element (100%, 91.7%), and ChM-I was infrequently immunolocalized to the spindle-shaped myoepithelial cells in the myxoid element (37.5%). Fibroblast growth factor-2 was strongly immunolocalized to the lacuna cells in the chondroid element (100%), among the neoplastic myoepithelial cells in the myxoid elements (96.9%), and on the basement membranes around the solid nests of neoplastic myoepithelial cells (71.4%). Although CD34 is a marker of endothelial cells, CD34 was expressed in the endothelial cells in only a few areas around the epithelial elements and in the fibrous element of pleomorphic adenomas. No signals for CD34 were observed in chondroid elements in pleomorphic adenomas (P < 0.001), but a few signals were seen in the myxoid elements (P < 0.05). These findings suggested that lacuna cells and neoplastic myoepithelial cells expressed ChM-I, and that this molecule may play an important role in hypovascularity and chondroid differentiation in pleomorphic adenoma. In conclusion, pleomorphic adenoma expressed ChM-I, which is involved in hypovascularity and chondroid formation in this type of tumor.  (+info)

Pulmonary epithelial-myoepithelial tumor of unproven malignant potential: report of a case and review of the literature. (5/197)

Epithelial-myoepithelial tumors of the lung are rare neoplasms whose biological behavior and clinical course still remain to be defined. A case of epithelial-myoepithelial tumor of the lung arising from bronchial mucosa-submucosa and occurring as a polypoid lesion of the upper left bronchus in a 47-year-old man is reported. The tumor did not infiltrate the cartilaginous wall of the bronchus and showed a biphasic histological appearance with a double layering of epithelial and myoepithelial cells. Myoepithelial spindle cells with eosinophilic cytoplasm were also observed. Mitotic figures were very rare and necrosis absent. Immunohistochemical study for epithelial and muscular markers confirmed the presence of a double-cell component in the tumor, namely epithelial and myoepithelial. The patient is alive and well, with no evidence of recurrent or metastatic disease 6 months after surgery. On the basis of the present case and the six previously reported cases, we suggest using the noncommittal term pulmonary epithelial-myoepithelial tumor of unproven malignant potential (PEMTUMP) for this type of neoplasm. In addition, we first introduce p63 as a novel marker for highlighting the myoepithelial cells of the respiratory tract and speculate on the role of these cells in the development of this unusual tumor.  (+info)

High-dose-rate endobronchial brachytherapy in endobronchial metastatic malignant chondroid syringoma. (6/197)

A 65-year-old man with malignant chondroid syringoma (MCS) was found to have pulmonary metastases in the form of multiple pulmonary nodules 4 years after wide excision and adjuvant radiotherapy of a primary abdominal wall tumor. Atelectasis of the lingula due to obstructive endobronchial metastasis, resistant to combination chemotherapy, led us to perform high-dose rate (HDR) endobronchial brachytherapy for the first time in this rare tumor with a favorable response. This case emphasizes the role of HDR brachytherapy as a palliative procedure in endobronchial tumors not responding to other treatment modalities, even those considered to be radioresistant.  (+info)

Translocation, deletion/amplification, and expression of HMGIC and MDM2 in a carcinoma ex pleomorphic adenoma. (7/197)

Carcinoma ex pleomorphic adenoma (CexPA) is a carcinoma developing within a pre-existing benign pleomorphic adenoma (PA). Here we describe the identification and characterization of a series of genetic events leading to translocation, deletion/amplification, and overexpression of the HMGIC and MDM2 genes in a CexPA at an early stage of development. The tumor had a pseudodiploid stemline karyotype with a del(5)(q22-23q32-33) and a t(10;12)(p15;q14-15). In addition, there were several sidelines with double minute chromosomes (dmin) or homogeneously staining regions (hsr). Fluorescence in situ hybridization (FISH) mapping revealed that the 12q14-15 breakpoint was located centromeric to HMGIC and that the entire gene was juxtaposed to the der(10) chromosome. Detailed analysis of cells with dmin and hsr revealed that HMGIC and MDM2 were deleted from the der(10) and that the dmin and hsr were strongly positive for both genes. Southern blot analysis confirmed that both HMGIC and MDM2 were amplified and that no gross rearrangements of the genes had occurred. Immunostaining revealed that the HMGIC protein was highly overexpressed particularly in the large polymorphic cells within the carcinomatous part of the tumor. These findings suggest that amplification and overexpression of HMGIC and possibly MDM2 might be important genetic events that may contribute to malignant transformation of benign PA.  (+info)

Intraosseous pleomorphic adenoma: case report and review of the literature. (8/197)

Pleomorphic adenoma is the most common neoplasm of the salivary glands, affecting mainly the parotid gland. The preferential intraoral site of this tumor is the palate. A case of a 31-year-old woman with an intraosseous pleomorphic adenoma located in the maxilla (left paramedian region), showing an approximate evolution of one year is reported. The present intraosseous case represents a rare location, with the tumor probably originating from glandular epithelial remnants captured during embryogenesis. In a review of the literature of 142 cases of intragnathic localization (24% in the maxilla) are identified. A slight predominance of women was observed (56%), with 55% of the patients being affected during the 5th to 7th decade of life. The tumors were malignant in 94% of the cases, with special predominance of mucoepidermoid carcinoma (65%). Intraosseous pleomorphic adenomas are rare, with the present patient being the 6th case reported in the literature and the second found in the maxilla. Mean age of the 5 previously reported cases was 58.8 years.  (+info)

Aims: To assess lymphatic vascular density (LVD) and lymph vessel endothelial proliferation in a series of carcinoma ex pleomorphic adenoma (CXPA) that represents the tumour in the different carcinogenesis phases and tumour progression.. Methods: In 8 cases of early CXPA (intracapsular and minimally invasive tumours), 8 of advanced CXPA (widely invasive tumours) and 10 of pleomorphic adenoma (PA) without malignant transformation, lymphatic vessels and proliferating cells were detected using the antibodies D2-40 and Ki-67 respectively.. Results: Comparing early tumours with advanced ones, LVD was not significantly different at the tumour margin. In contrast, regarding intratumoural lymphatics, PA without malignant transformation and early CXPA contained rare, if any, lymph vessels, whereas in widely invasive carcinomas they were more numerous. However, neither intratumoural nor peritumoural LVD were increased in comparison to adjacent normal salivary gland tissue. In no case did dual ...
TY - JOUR. T1 - Concurrent cytogenetic, interphase fluorescence in situ hybridization and DNA flow cytometric analyses of a carcinoma ex-pleomorphic adenoma of parotid gland. AU - El-Naggar, Adel K.. AU - Lovell, Mercedes. AU - Callender, David L.. AU - Ordonez, Nelson G.. AU - Killary, Ann M.. PY - 1998/12/1. Y1 - 1998/12/1. N2 - We report the cytogenetic, fluorescence in situ hybridization (FISH), and DNA ploidy analyses of a high grade carcinoma ex-pleomorphic adenoma of the submandibular gland. Our overall combined analyses showed a marked DNA aneuploidy and numerical abnormalities involving all chromosomes. Cytogenetic analysis revealed a near tetraploid modal chromosomal number with tetraploid loss of chromosomes Y, 1, 6, 9, 11, 14, 15, 17, and 19-21 and hypertetraploid gain of chromosomes 7, 8, and 22. The structural abnormalities included der(1;14)(q10;q10),del(6)(q15q34),+del(6)(q15q34),+der(8)t(1;8)(q12;q12.2),de r(9;19)(q10;q10),add(14)(p11.2),i(20)(q10),der(21)t(8;21)(q11.2;q22.3), ...
TY - JOUR. T1 - Salivary gland-type mixed tumor (pleomorphic adenoma) of the lung. AU - Carretta, Angelo. AU - Libretti, Lidia. AU - Taccagni, Gianluca. AU - Zannini, Piero. PY - 2004/12. Y1 - 2004/12. N2 - Primary pleomorphic adenomas of the respiratory tract are rare tumors. They usually originate from the bronchial glands, but may also be unrelated to the bronchial tract and be localized in the pulmonary parenchyma. These salivary-gland type neoplasms have peculiar histological and clinical features: they usually behave as low-grade malignant neoplasms, but may also have more aggressive features. The diagnostic and therapeutic approach in a patient with a pulmonary pleomorphic adenoma is described.. AB - Primary pleomorphic adenomas of the respiratory tract are rare tumors. They usually originate from the bronchial glands, but may also be unrelated to the bronchial tract and be localized in the pulmonary parenchyma. These salivary-gland type neoplasms have peculiar histological and clinical ...
TY - JOUR. T1 - Pleomorphic adenoma of nasal septum. T2 - A rare case. AU - Shetty, Shama. AU - Nayak, Dipak Ranjan. AU - Jaiprakash, Padmapriya. PY - 2018/1/1. Y1 - 2018/1/1. N2 - The most common benign tumour of the major salivary glands is the pleomorphic adenoma. They are seen rarely in the minor salivary glands, usually in hard palate, soft palate and nasopharynx. Pleomorphic adenomas in nasal cavity are unusual and may be misdiagnosed because they have predominant myoepithelial cellularity and fewer myxoid stromata compared with those elsewhere. We present a case of 38-year-old male with a 2-year history of left nasal obstruction and epistaxis since 6 months. Diagnostic nasal endoscopic examination showed a soft lobulated mass in left nasal cavity attached to anterior part of the septum. Radiological examination demonstrated soft tissue mass filling left nasal cavity with an eroded septum. The biopsy from the mass was suggestive of pleomorphic adenoma and was resected endoscopically. ...
Pleomorphic adenoma is the most common salivary gland tumor on the head and neck region [1]. Metastasizing pleomorphic adenoma is a rarely detected form of clinic antity [2,3]. According to the World…
MRI and PET images demonstrate a right parotid pleomorphic adenoma. Pleomorphic adenomas are the most common salivary gland tumours. This case was donated to Radiopaedia.org by Radswiki.net
Fifty-two cases of pleomorphic adenoma of minor salivary gland origin and seventy-two cases of pleomorphic adenoma of major salivary gland origin were examined for the presence of hyaline cells (plasmacytoid cells). Hyaline cells were found in 38 percent of the minor salivary gland cases and 21 perc …
Salivary gland tumors most commonly occur in the parotid gland, accounting nearly 85% of all salivary gland tumors. But, 25% of parotid tumors are malignant (cancerous).. Pleomorphic adenoma is the most common type of benign salivary gland tumor. It is typically a slow growing tumor and occur most often in the parotid gland. It is also known as mixed tumor which describes its pleomorphic appearance as opposed to its dual origin from epithelial and myoepithelial elements.. The tumor is usually solitary and presents as a slow growing, painless and firm singular nodal mass. It is usually mobile unless found in the palate and can cause atrophy of the mandibular ramus when located in the parotid gland.. ...
This study was undertaken to evaluate and concentrate on the recurrent pleomorphic adenomas (PAs) of the parapharyngeal space. The records of 9 patients treated for recurrent PAs occupying parapharyngeal space were retrospectively reviewed. The study population comprised 6 women and 3 men with a mean age of 51 (range, 35-79 years). Before the first revision surgery, imaging studies and clinical examinations showed 1 solitary mass in 4 patients, 2 solitary masses in 3 patients, and 3 or more masses in 2 patients. After first revision surgery, 4 patients had rerecurrences with multinodular disease. Two of 4 patients underwent radiation therapy (RT), and the other 2 patients underwent second revision surgery, among whom 1 patient underwent third revision surgery, and the other one was also submitted to RT. Overall, 12 reoperations were performed, and at the end of all operations, 4 patients had rerecurrences and residual disease. In conclusion, we recommend RT to patients with multinodular disease, ...
Bruno Galletti, Francesco Freni, Francesco Gazia, Viviana Nicastro, Pietro Abita, Federico Sireci , Francesco Galletti. Parapharyngeal space lesions account for only 0.5% of head and neck tumours. A 63-year-old male presented primary pleomorphic adenomas arising de novo from minor salivary glands in the parapharyngeal space. We describe the clinical features, pathology, radiological findings and treatment of this lesion. The goal when presented with such a tumour is a correct diagnosis and the in toto excision of the tumor to avoid any recurrence.. Sireci_02.pdf. ...
Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous glandular cells along with myoepithelial components, having a malignant potentiality. It is the most common type of salivary gland tumor and the most common tumor of the parotid gland. It derives its name from the architectural Pleomorphism (variable appearance) seen by light microscopy. It is also known as Mixed tumor, salivary gland type, which describes its pleomorphic appearance as opposed to its dual origin from epithelial and myoepithelial elements. The tumor is usually solitary and presents as a slow growing, painless, firm single nodular mass. Isolated nodules are generally outgrowths of the main nodule rather than a multinodular presentation. It is usually mobile unless found in the palate and can cause atrophy of the mandibular ramus when located in the parotid gland. When found in the parotid tail, it may present as an eversion of the ear lobe. Though it is ...
Synchronous pleomorphic adenomas of the major salivary glands: a case report.: The presentation of multiple distinct tumors in major salivary glands is rare. Al
Purpose: We sought to identify genomic alterations (GAs) in salivary gland adenocarcinomas, not otherwise specified (NOS), salivary duct carcinomas (SDC), carcinoma ex pleomorphic adenoma (ca ex PA), and salivary carcinoma, NOS. Experimental design: DNA was extracted from 149 tumors. Comprehensive genomic profiling (CGP) was performed on hybridization-captured adaptor ligation-based libraries of 182 or 315 cancer-related genes plus introns from 14 or 28 genes frequently rearranged for cancer and evaluated for all classes of GAs. Results: 590 GAs were found in 157 unique genes (mean 3.9/tumor). GAs in the PI3K/AKT/mTOR pathway were more common in SDC (53.6%) than other histologies (p=0.019) Cyclin dependent kinase GAs varied amongst all histotypes: adenocarcinoma, NOS (34.6%); SDC (12.2%); ca ex PA (16.7%); carcinoma, NOS (31.2%) (p=0.043). RAS GAs were observed: adenocarcinoma, NOS (17.3%); SDC (26.8%); ca ex PA (4.2%); and carcinoma, NOS (9.4%) (p=0.054). ERBB2 GAs, including amplifications and ...
Salama AR, Sakellariou T, The Cervicofacial Advancement Flap, Oral and Maxillofacial Surgery Clinics of North America, 2014. Nadershah M, Alshadwi A, Salama A An unusual case of carcinoma ex pleomorphic adenoma of the parotid metastasizing to the mandible: case report and review of the literature. J Oral Maxillofac Surg. 2013 Feb;71(2):437-42.. McClure SA, Movahed R, Salama A, Ord RA Maxillofacial metastases: a retrospective review of one institutions 15-year experience. Oral Maxillofac Surg. 2013 Jan;71(1):178-88.. Sönmez TT, Prescher A, Salama A, Kanatas A, Zor F, Mitchell D, Zaker Shahrak A, Karaaltin MV, Knobe M, Külahci Y, Altuntas SH, Ghassemi A, Hölzle F.Comparative clinicoanatomical study of ilium and fibula as two commonly used bony donor sites for maxillofacial reconstruction.Br J Oral Maxillofac Surg. 2013 Aug 27.. Zhang T, Lubek JE, Salama A, Dyalram D, Liu X, Ord RA. Treatment of cT1N0M0 Tongue Cancer: Outcome and Prognostic Parameters. J Oral Maxillofac Surg. 2013 Sep 14. ...
METHODS: This cross-sectional study comparatively evaluated 21 cases of pleomorphic adenomas and 21 sections of regular oral mucosa from the files of an oral pathology department. The tissue sections were subjected to immunohistochemical study with a monoclonal antibody specific to CD31 protein to assess vascular density and were also stained with Sirius red to evaluate the levels of collagen. The numbers of positively-stained cells were enumerated in specific fields through morphometric study, with subsequent statistical analysis ...
title: Sinonasal pleomorphic adenoma: A single institution case series combined with a comprehensive review of literatures, doi: 10.1016/j.anl.2018.08.003, category: Article
The proto-oncogene, pleomorphic adenoma gene-like 2 (PLAGL2), is implicated in a variety of cancers including acute myeloid leukemia (AML), malignant glioma, colon cancer, and lung adenocarcinoma. There is additional evidence that PLAGL2 can function
TY - JOUR. T1 - Pleomorphic adenoma with extensive adipose content. AU - Jin, Y. T.. AU - Lian, J. D.. AU - Yan, J. J.. AU - Hwang, T. Z.. AU - Tsai, S. T.. PY - 1996/1/1. Y1 - 1996/1/1. UR - http://www.scopus.com/inward/record.url?scp=0030058826&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0030058826&partnerID=8YFLogxK. U2 - 10.1046/j.1365-2559.1996.t01-2-258289.x. DO - 10.1046/j.1365-2559.1996.t01-2-258289.x. M3 - Article. C2 - 8838128. AN - SCOPUS:0030058826. VL - 28. SP - 87. EP - 89. JO - Histopathology. JF - Histopathology. SN - 0309-0167. IS - 1. ER - ...
Question - Hi, I have an pleomorphic adenoma which has stayed the same - 6F. Find the answer to this and other Medical questions on JustAnswer
Sudhir Kumar Vujhini1, Kandukuri Mahesh Kumar2, Konduru Omkareshwar3, Sridhar Reddy4, Ganesh5. 1Associate Professor, 2Assistant Professor, 3Associate Professor, Department of Pathology, Malla Reddy Institute of Medical Sciences, Hyderabad. 4MDS PG, MNR Dental College, Sanga Reddy, Medak. 5Assistant Professor, Malla Reddy Institue Of Dental Sciences, Suraram, Hyderabad.. Abstract: Pleomorphic adenoma also called benign mixed tumor, is the most common salivary gland tumor. Most of these tumors occur in major salivary glands; Parotid gland happens to be the commonly involved one (about 90 %) and about 10 % of these occur in the minor salivary glands. The most common sites for pleomorphic adenoma of minor salivary glands are the palate, followed by the lips, the cheeks, floor of the mouth, tongue, tonsil, pharynx, the retromolar area and the nasal cavity. FNAC of intraoral swellings is rarely advised. Here, we are reporting a rare case of pleomorphic adenoma arising from the palate diagnosed on FNA ...
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Non-contrast studies -- Sagittal SE T1-weighted MR image reveals a well-circumscribed hypointense mass lesion compared with surrounding parotid tissue, within the superficial lobe.
Non-contrast studies -- Coronal fat-suppressed FSE T2-weighted MR image reveals a well-circumscribed hyperintense mass lesion compared with surrounding parotid tissue, within the superficial lobe, ...
SS noted some prominence of her right eye with mild discomfort over several months. Examination found 2 mm of proptosis on the right side and mild inferior displacement of the globe. A-scan...
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The surgical risks involved in the removal of the tumor vary with the tumor itself. A smaller, more confined tumor will be easier to remove and therefore be less likely to cause damage to the facial nerve located nearby. A tumor that extends to a wider area may carry heavier risk. According to Georgetown University Hospital, surgeons are extremely careful in working near the facial nerve and most patients heal normally and do not experience any abnormal function. ...
An Unusual Variant of a Common Palatal Salivary Gland Tumor: Case Report of a Pleomorphic Adenoma with Significant Lipomatous Metaplasia ...
Patients, Carcinoma, Saliva, Syndrome, Tissue, Adenoma, Pleomorphic Adenoma, Association, Cancer, Carcinomas, Cell, Head, Human, Lymph, Lymph Node, Metastases, Neck, Risk, Squamous Cell Carcinoma, Tongue
A 68-year-old man was referred to our oculoplastics clinic by his primary ophthalmologist with a three month history of an expanding mass in his left superotemporal orbit. He had been followed yearly with CT scans since a recurrent left lacrimal gland lesion was removed 26 years ago. The initial lesion was resected 13 years prior to that, when the patient was 29 years old. The pathology reports from both surgeries described a pleomorphic adenoma of the lacrimal gland with no malignant criteria. Neither report indicated whether the tumor had been completely resected. The last CT scan was performed almost a year before symptoms started and was read as stable with no tumor recurrence. His only current complaint was of slight episodic pain in the affected area. He denied any diplopia, vision loss, headache or other systemic symptoms. He was also treated for hypertension, hypothyroidism and dyslipidemia ...
TY - JOUR. T1 - Intrasellar salivary gland-like pleomorphic adenoma. T2 - Case report. AU - Takahashi, Satoshi. AU - Mikami, Shuji. AU - Akiyama, Takekazu. AU - Kawase, Takeshi. PY - 2011/2/1. Y1 - 2011/2/1. N2 - BACKGROUND AND IMPORTANCE: We present a rare case of a patient with intrasellar salivary gland-like pleomorphic adenoma and review the 2 previously reported cases of the clinical entity to identify their common clinical features. CLINICAL PRESENTATION: A 56-year-old Asian man visited our hospital with a chief complaint of visual disturbance caused by brain tumor that filled up the sella turcica with suprasellar extension. The patient underwent craniotomy via a left pterional approach, and the subdural, intracranial portion of the tumor was totally removed, with every artery and nerve preserved. Pathological diagnosis of the tumor was intrasellar salivary gland-like pleomorphic adenoma. Three years after the operation, the patient remains free from tumor recurrence. CONCLUSION: Tumors in ...
Discussion: Myoepithelial carcinomas (or malignant myoepitheliomas) are rare malignant salivary gland neoplasms in which the tumor cells show myoepithelial differentiation. The entity was first described by Stromeyer et al. in 1975. The tumor was included in the WHO classification of salivary gland neoplasms as a distinct clinicopathologic entity in 1991. About 60% to 70% of myoepithelial carcinomas develop in a benign mixed tumor (carcinoma ex pleomorphic adenoma), and the remainder arise de novo. Histologically, malignant myoepitheliomas are composed of one or several cell types: spindle, plasmacytoid, epithelioid, and clear cells. Frequently, one of the cell types predominates. The neoplastic cells grow either as multiple nodules or as large solid sheets separated by variable amounts of intervening hyaline or myxoid stroma. By far, the multinodular growth pattern is more prevalent. The cytologic features generally reflect the histology. The cytologic smear can show spindle, epithelioid or ...
OBJECTIVE: The aim of this study was to report the clinicopathological features of 18 epithelial tumors of the lacrimal gland treated in a single institution. STUDY DESIGN AND SETTING: Clinical data and treatment were recorded and histological features reviewed. RESULTS: Twelve tumors (66.7%) were adenoid cystic carcinoma (ACC), 5 (27.8%) pleomorphic adenoma (PA), and 1 (5.5%) carcinoma ex pleomorphic adenoma. All patients with ACC presented with advanced clinical stage, and most were treated by wide surgical resection followed by adjuvant radiotherapy. No recurrence was observed in 4 cases of ACC; however, 7 patients died from persistence of disease or by local and/or distant recurrence. All PA patients were successfully treated by surgical resection. CONCLUSIONS: Epithelial lacrimal gland tumors are mainly PA and ACC, and malignancies are more common than benign tumors. Although ACC presented typically with advanced clinical stage, 33% of the patients survived without tumor recurrence or ...
TY - JOUR. T1 - Is c-kit (CD117) immunolocalization in cell block preparations useful in the differentiation of adenoid cystic carcinoma from pleomorphic adenoma?. AU - Chandan, Vishal S.. AU - Wilbur, David. AU - Faquin, William C.. AU - Khurana, Kamal K.. PY - 2004/8/25. Y1 - 2004/8/25. N2 - The authors examined the role of c-kit antigen expression in cell block material obtained by fine-needle aspiration in differentiating between adenoid cystic carcinoma and pleomorphic adenoma. It was found that c-kit expression was not restricted to adenoid cystic carcinomas; instead, c-kit was expressed in pleomorphic adenomas as well. Thus, c-kit was not useful in distinguishing between these two types of lesions.. AB - The authors examined the role of c-kit antigen expression in cell block material obtained by fine-needle aspiration in differentiating between adenoid cystic carcinoma and pleomorphic adenoma. It was found that c-kit expression was not restricted to adenoid cystic carcinomas; instead, ...
Chordomas are rare tumors that are usually located in the sacrococcygeal and sphenooccipital region. Their cytologic diagnosis is rather straightforward when sampled by fine-needle aspiration (FNA) from these characteristic locations, especially when physalipherous cells are present. However, chordomas may pose difficult diagnostic challenges when encountered in unusual locations, such as the parapharyngeal region. We report the cytologic findings of a recurrent chordoma sampled through transoral FNA from the parapharyngeal space of a 66-year-old woman. As the prior history of chordoma was not available during the rapid onsite evaluation, the presence of bland epithelioid nonvacuolated cells and spindle cells intimately admixed with a fibrillary, intensely metachromatic material led to an initial diagnosis of pleomorphic adenoma. Review of the patients prior pathology specimen and of the Papanicolaou-stained smears and cellblock sections showing rare multivacuolated (physalipherous) cells led ...
Abstract Introduction: Polymorphous low grade adenocarcinoma (PLGA) is a rare salivary gland neoplasm with an indolent course. It occurs primarily in the minor salivary glands but can rarely occur in the major salivary glands. It usually occurs in the fifth to seventh decades of life with female preponderance. Case Report: A 16-year-old male presented with recurrent painless swelling in the right preauricular region and with a history of surgical intervention at the same site in the past. His histopathology report was suggestive of pleomorphic adenoma. The swelling recurred after one year of excision and a superficial parotidectomy was performed. The detailed histopathological examination was suggestive of Polymorphous low grade adenocarcinoma. In view of close margins, the patient was given adjuvant radiotherapy. Thirty-three months post-surgery, he is alive and disease-free. We describe a rare case of PLGA of the parotid gland in a teenager with its clinical characteristics, histopathological
E-cadherin is a calcium dependent cell adhesion molecule, important in cell to cell interactions in epithelial tissues. The present study examined E-cadherin expression in normal salivary glands, pleomorphic adenoma, Warthins tumor, mucoepidermoid carcinoma, acinic cell carcinoma, adenoid cystic carcinoma and adenocarcinoma of salivary glands in paraffin sections using a monoclonal antibody (5H9). This study is firstly reported E-cadherin expression in the salivary gland and tumors.,BR,In normal submandibular and parotid gland, E-cadherin staining was confined to the cell membrane of acinar and ductal cells. In excretory ducts, high columnar cells showed the strongest reaction at the basal aspect and ductal basal cells were weakly positive or negative, the basement membrane zone lacked staining. No E-cadherin reaction was observed in modified myoepithelial cells and plasmacytoid cells. In pleomorphic adenoma and mucoepidermoid carcinoma, E-cadherin was positive at the lateral cell membrane or ...
Canalicular adenoma is a type of benign salivary gland tumor that occurs most often in minor salivary glands. In addition to pleomorphic adenoma, the two are the most common tumors of the upper lip. In 95% of cases, canalicular adenoma occurs on the upper lip. The next most common location is the buccal mucosa (inner cheek). Other sites of the mouth, including the parotid gland, are rare for this disease. Canalicular adenoma is most likely to occur in older adults around 70 years of age. There is a predilection for gender with most cases being in females. Canalicular adenoma is characterized as a slow growing, painless swelling, whose diameter can be up to 2 cm. It can be normal or bluish in color. The appearance of this tumor microscopically is very distinct. There are cords of columnar or cuboidal epithelium, which have basophillic nuclei. Parallel rows of cords appear to form long canals. Frequently, there are large cystic spaces. There are no stromal alterations evident. Treatment usually ...
Classically these tumors show biphasic manifestation with admixture of varying amounts of polygonal salivary gland cells and spindle shaped myoepithelial cells. The underlying stroma could be mucoid / myxoid / cartilagenous / hyaline. Even though these tumors are not encapsulated but thickening of parotid fascia around the mass gives it an encapsulated appearance (pseudocapsule).. The main cause for this tumor is juxtapositioning of PLAG gene to the gene for beta catenin. This causes activation of catenin pathway leading on to inappropriate cell division.. ...
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Pleomorphic adenoma, also known as benign mixed tumor, is the most common tumor of salivary gland origin, accounting for about 60-70% of all salivary gland tumors (Peel and Seethala, 2007; Downer, et al., 2011; Papadogeorgakis ...
On one of the first three fridays in october, the president of the college cancels classes and declares it mountain day. Surgical treatment of pleomorphic adenoma of the parotid gland: report of cases
This post is part of a wider series about all the 6 CX disciplines that represent the CXPA Framework around which the CCXP exam is structured and that we cover in the CX Masterclass. Follow Nienke Bloem and Rosaria Cirillo to be notified as soon as a new blog post is published.. Find here the complete list of the other posts in this series:. 1. CX Strategy. 2. Customer Understanding. 3. Design, Improvement and Innovation. 4. Measurement. 5. Governance. 6. Culture (will be published on the 4th of December). Extra: CXPA exam & Becoming CCXP (will be published on the 11th of December). About this series. This post was originally posted on Wow Now and is part of the CX Framework series by Rosaria Cirillo and Nienke Bloem.. The foundations for these blogposts are written by Milou van Kerkhof following the June 2017 CX Masterclass given by Nienke Bloem and Rosaria Cirillo. Milou attended this as a newcomer in Customer Experience. These blogposts have been slightly edited and reflect only the ...
The Certified Customer Experience Professional (CCXP) credential requires ongoing professional development to maintain an active certification status. As such, certificants are required to complete 20 hours of CCXP Renewal Credits (CRCs) in order to renew their certification every two years. The renewal date of the new certificate will be two years from the expiration date of the last certificate issued.. One CRC is earned for each hour (60 minutes) spent in a planned, structured professional development activity. CRCs will be accepted for the certification renewal requirement as long they are directly related to the CCXP Exam Blueprint and meet the guidelines listed below. CCXPs must earn a total of 20 CRCs in a minimum of two of the professional development activity categories (Program attendance, Speaking, College or University Courses, CXPA Contributions) for renewal. CRCs accumulate for a two-year period starting immediately after the certification is issued and cannot be carried over to ...
Learn about the causes, symptoms, diagnosis & treatment of Tumors of the Head and Neck from the Professional Version of the Merck Manuals.
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Medical information, Adenoma - secreting. Definition of Adenoma - secreting, symptoms of Adenoma - secreting, treatment of Adenoma - secreting, and prevention of Adenoma - secreting. Exams and Tests Adenoma - secreting.
Looking for information on Adenoma? Medigest has all you need to know about Adenoma - Symptoms and Signs, Causes, Treatments and definition
ဆေးပညာအချက်အလက်များကို Hello Sayarwon တွင်ရှာဖွေနိုင်ပြီး၊ Bronchial adenoma (လေပြွန်အကျိတ်ဖြစ်ခြင်း) , ၏ အဓိပ္ပါယ်ဖွင့်ဆိုချက်၊ ဖြစ်ပွားမှု အကြောင်းရင်းများနှင့် လက္ခဏာများ၊ အဖြေရှာကုသပုံများကိုလည်း ရှာဖွေနိုင်ပါသည်။
Introduction: Treatment of choice for pleomorphic adenoma of the hard palate is wide local resection of the tumor including the overlying mucosa and underlying periosteum. Most conventional methods for covering the resulting palatal wound are prosthetic devices. In this case, we examined the validity of grafting a polyglycolic acid sheet and fibrin glue over a mucosal defect of the palate with a bony surface, as a substitute for a surgical splint. Case Report: A 39-year-old male presented with a large, solid mass located on the right hard palate. Fine-needle aspiration cytology suggested pleomorphic adenoma. The patient underwent wide local resection of the lesion, and the mucosal defect was immediately covered with polyglycolic acid sheets, that were fixed with a fibrin glue spray. These sheets were tightly placed and remained in the wound, which led to complete epithelialization of the wound surface. Conclusion: Grafting the polyglycolic acid sheet with fibrin glue fixation is a useful substitute for
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether radiation therapy is more effective when given together with chemotherapy or alone after surgery in treating salivary gland tumors.. PURPOSE: This randomized phase II/III trial is studying radiation therapy with or without chemotherapy to see how well it works in treating patients with high-risk malignant salivary gland tumors that have been removed by surgery. ...
Malignant salivary gland tumours are staged using the TNM staging system: T: Tumour Tx: primary tumour cannot be assessed T0: no evidence of primary tumour T1 less than or equal to 2 cm in maximal diameter no extra-parenchymal extension T2...
Salivary Heparanase Level Is a Potential Biomarker to Diagnose and Prognose the Malignant Salivary Gland Tumor. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
The success rate of these procedures is very much dependent on the ability of the operator and the equipment used. The equipment has to have the capabilities to operate at very low power because the syringoma are not very thick and a powerful ablation could result in damage to the dermis and therefore permanent scarring.. The method used to remove the syringoma by Electrodesiccation is very simple and this involves simply ablating the lesions from the top and level it off with the rest of the surrounding skin. However since the syringoma reside inside the dermis as well, in order to minimise recurrence it is advisable to ablate them deeper inside the dermis. This is because it has been reported that most of the recurrence of syringoma is due to the fact that simply leveling off the syringoma with the surrounding skin is not sufficient to remove them completely and they will regrow soon after healing. A couple of weeks after the cosmetic procedure.. ...
Summary: A 38-year-old woman presented with a mass on her left hand that had been gradually increasing in size over a 3-year period. Hand radiography was ob...
OUTLINE: This is a multicenter study.. Patients receive gemcitabine IV over 30 minutes on days 1 and 8. Patients also receive either cisplatin IV over 1 hour on day 2 OR carboplatin IV over 30 minutes on day 1. Treatment repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity.. Patients are followed at 4 weeks, every 3 months for 1 year, and then every 6 months thereafter until relapse.. PROJECTED ACCRUAL: A total of 11- 34 patients will be accrued for this study within 1.5-3 years. ...
Ram Babu1, Sudhir Kumar Vujhini2, Prathima3, Ram Manohar Lohia4, Kandukuri Mahesh Kumar5. 1Assistant Professor of Pathology, E.S.I Model Hospital, Nacharam, Hyderabad, Andhra Pradesh.. 2Associate Professor of Pathology, MRIMS, Suraram, Hyderabad, Andhra Pradesh.. 3Assistant Professor of Pathology, Osmania Medical College, Hyderabad, Andhra Pradesh. 4Department of Radiology, E.S.I Model Hospital, Nacharam, Hyderabad, Andhra Pradesh 5Assistant Professor, Department of Pathology, MRIMS, Suraram, Hyderabad. Abstract:. Lymphadenopathy can masquerade as other pathological entities due to their proximity to many sites, thus clinical misjudgment can happen. Ours is such example where Granulomatous cervical lymphadenopathy is clinically thought of as Pleomorphic adenoma of Parotid gland. They need careful review, radiological correlation before committing for final impression.. Key words: Parotid, Pleomorphic adenoma, Lymphadenopathy, Granulomatous Cervical lymphadenitis, Fine needle aspiration ...
Examples adenoid cystic carcinoma cribriform adenocarcinoma of minor salivary glands polymorphous adenocarcinoma pleomorphic adenoma (...)
TY - JOUR. T1 - Loss of heterozygosity and microsatellite alterations in p53 and RB genes in adenoid cystic carcinoma of the salivary glands. AU - Yamamoto, Yuzo. AU - Virmani, Arvind K.. AU - Wistuba, Ignacio I.. AU - McIntire, Donald. AU - Vuitch, Frank. AU - Albores-Saavedra, Jorge. AU - Gazdar, Adi F.. PY - 1996/1/1. Y1 - 1996/1/1. N2 - Adenoid cystic carcinomas (ACC) constitute approximately 20% of malignant salivary gland tumors. Several histological types of ACC are recognized and may coexist in a single tumor. The authors divided ACC into lower grade (tubular and cribriform subtypes) and higher grade (trabecular and solid) subtypes. A preliminary analysis of 10 ACCs showed a relatively high incidence of loss of heterozygosity (LOH) at the p53 and RB genes and low or absent K-ras mutations and LOH at chromosomal loci 3p, 5q, 8p, and 9p. From 21 tumors, the authors carefully microdissected and analyzed 36 subtype foci. Three interrelated pieces of evidence indicate that the relatively poor ...
A 32 year old woman presented with a large swelling in the left parotid area. Past history revealed that the patient had undergone enucleation of a left parotid mass at 9 years of age that showed calcular atrophy with sialadenitis, and superficial parotidectomy of a recurrent mass at 15 years of age that was considered pleomorphic adenoma. A magnetic resonance imaging showed an 11.8 x 6 cm mass in the left parotid area extending into the infratemporal fossa and the parapharyngeal space. The mass was removed by total parotidectomy. ...
Introduction Minor salivary gland neoplasms of epithelial origin are rare in children and adolescents and most are not well documented, except for a few small series and case reports. This study...
Dermatol Sinica 4: 1-6, 1986. Seven cases of chondroid syringoma of the skin collected from 1983 to 1985 are reported. The patients ranged from 26 to 58 years of age and 4 of them were male. They presented as asymptomatic solitary dermal or subcutaneous nodule. The sites of predilection were the nose (4 cases) and the chin (2 cases); one unusual case occurred on the foot. The tumors were well circumscribed and composed of epithelial cells forming solid nests or glandular structures in a chondroid or myxoid stroma. Squamous metaplasia was occasionally observed. Except one case with 3 recurrences, the others did not recur. A complete surgical excision is usually adequate. ...
Salivary Gland Tumor Removal clinics in Romania at the best price. Find doctors, specialized in Ear, Nose and Throat (ENT) and compare prices, costs and reviews.
Syringoma: A benign tumor of the sweat glands which is usually multiple and results from malformation of sweat ducts. It is uncommon and more common in females than in males. It is most likely to appear at adolescence, and further lesions may develop during adult life. It does not appear to be hereditary. (Rook et al., Textbook of Dermatology, 4th ed, pp2407-8)
Syringoma on the penis can be quite distressing and worrisome for most individuals. People often fear the lesion for being sexually transmitted such as condyloma accuminata.
We present a case of cutaneous leiomyomas (CL) arising in a pleomorphic adenoma (PA) of the parotid gland. PA and CL are benign tumors arising from the parotid gland and the erector pilli muscle, respectively. They both have a benign clinical course and in most cases leiomyomas are multiple in nature. PAs of the parotid are the most frequent benign tumors of the major salivary glands. To our knowledge this is the first case of PA with CL.
We show that TRH mRNA is expressed in human fetal and adult pancreata, and that TRHR mRNA is expressed in fetal human pancreas but not in adult human pancreas. Comparative evaluation between two immunoenzymatic techniques (FAST and cialis reviews by men Phadezym) and the Phadebas RAST in food allergy. Implications for community interventions and directions for future research are discussed.. PBX1 expression correlated with histologic neuroblastoma cialis pills subtypes, with highest expression in benign ganglioneuromas and lowest in high-risk neuroblastomas. Insulin temperature and stability under simulated transit conditions.. We attempted a meta-analysis of telemedicine research studies of the costs associated with telemedicine. The purpose of this study is to evaluate the usefulness of dual-time-point 18F-FDG cialis patent expiration date extended PET/CT for discriminating between benign and malignant salivary gland tumors. The study included 18 eyes of 16 patients who underwent cataract ...
|b||i|Background: |/i||/b|Salivary gland tumors (SGTs) are known for their specific heterogeneity and ambiguous outcome for the affected patients. The |i|LKB1 |/i|a
In a sense, though I tend to do all right with them, I truly hate the whole multiple choice approach to medicine. My diagnostic capability is not based on whether I can recognize a tyrosine crystal in a single poorly 2D image from a pleomorphic adenoma slide. What is my triage method? What tests do I run on a scant specimen? If I have a malignancy of unknown origin in an elderly womans pleural fluid, I dont need to have the second leading cause of malignant pleural effusions memorized and then try to figure out whether the questions as written ten years ago or ten months ago and whether a few things switched places on the charts. I need a basic, streamlined workup that is most likely to lead me to the correct diagnosis for the least money and waste of specimen. I need to know when to ask for help, when to ask for flow cytometry, and when to get a cell block and what stains to order on the cell block, and when to stop throwing money and time down the drain and call the clinician to ask for ...
In a sense, though I tend to do all right with them, I truly hate the whole multiple choice approach to medicine. My diagnostic capability is not based on whether I can recognize a tyrosine crystal in a single poorly 2D image from a pleomorphic adenoma slide. What is my triage method? What tests do I run on a scant specimen? If I have a malignancy of unknown origin in an elderly womans pleural fluid, I dont need to have the second leading cause of malignant pleural effusions memorized and then try to figure out whether the questions as written ten years ago or ten months ago and whether a few things switched places on the charts. I need a basic, streamlined workup that is most likely to lead me to the correct diagnosis for the least money and waste of specimen. I need to know when to ask for help, when to ask for flow cytometry, and when to get a cell block and what stains to order on the cell block, and when to stop throwing money and time down the drain and call the clinician to ask for ...
This lesion is described as a soft tissue enlargement. Reactive soft tissue enlargements can be excluded from differential diagnosis because the lesion has been present for several years and is progressively enlarging. Also, the lesion is not painful, except for occasional soreness associated with the denture.. Within the category of tumors, malignant tumors can be excluded because the lesion is very slowly growing and essentially asymptomatic. Soft tissue cysts are eliminated because they are fluid filled and have “hydraulic†properties, meaning that they are compressible and expand in all directions uniformly. Cysts do not have a surface with a depression or fissure.. From the category of benign tumors, epithelial lesions and salivary gland tumors can be excluded. Epithelial lesions can be excluded because these have a white, rough surface. Salivary gland tumors can be excluded because the lesion appears to be arising from the alveolar ridge mucosa. Salivary gland tumors may arise ...
Most salivary gland tumors are benign and occur in parotid gland. The most common sign of a salivary gland tumor is a painless mass.
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If you are suffering from itchy vulva that is unresponsive to several oral and topical medication, you may have vulvar syringomas.
RODERIC (Repositori dObjectes Digitals per a lEnsenyament la Recerca i la Cultura) es el repositorio institucional de la Universitat de València. Se concibe como una ventanilla única para el acceso y la difusión de la producción digital de la Universitat. RODERIC responde al compromiso de la Universitat con el movimiento de acceso abierto al conocimiento adquirido con su adhesión a la Declaración de Berlín (30 Septiembre de 2008).
Oral tumors - skin tumors - salivary gland tumors - craniofacial tumors: in communion with the teachings of oral pathology, ENT, ophthalmology; study of precancerous lesions, etiology and pathogenesis of tumors, their biology and clinical behavior, diagnostic and classification framework, therapy principles with particular reference to the two aspects of surgery: demolition and reconstruction. Basic principles of oncological and radiant treatment ...
Adenoid cystic carcinoma (ACC) is a relatively rare form of cancer that most commonly develops in the salivary glands or other regions of the head and neck.
Zdravljenje adenoma prostate z repom. Kljub očitnemu napredku pri zdravljenju adenoma prostate, tradicionalne medicine, so metode, uporabljene za zdravljenje te bolezni pred stoletjem, še vedno pomembne. Takšno zdravljenje adenoma prostate z ljudskimi zdravili je zelo učinkovito, zato bo rezultat opazen hitro. Sončnična semena. Priporočljivo je, da jedo suho (vendar ne ocvrto) bučno seme. Pred uporabo je treba izdelek očistiti iz trde lupine, zelena folija pa mora ostati. Vzemite to sredstvo priporočljivo za gramov na dan za mesec. ljudsko zdravljenje. Ali se adenoma zdravi brez prizadevanj pacienta in kakšne so možne posledice, na recepciji zdravnik vsakemu posamezniku pojasni posamezno. Sprememba načina. Bolniki z adenoma prostate so večinoma starejši od 50 let. Pogosteje so moški s prekomerno težo, ki se ne želijo omejiti v hrani, preživeti čas na televiziji. Pri ljudskih metodah je bilo zdravljenje s čebelasto poddomenom adenoma prostate pridobljeno z obsežnim obsegom. ...
Če se ne sprejmejo terapevtski ukrepi, se pri bolnikih z adenomi prostate lahko razvije kronična ledvična odpoved. Pri adenoma prostate se včasih razvije akutno zadrževanje urinov. Pacient ne more urinirati, ko je mehur je poln, kljub intenzivni želji. Za odpravo zadrževanja sečnice se pri moških kateterizira mehur, včasih pa je nujna operacija ali prebadanje mehurja.. Še en zaplet pri adenoma prostate je hematurija. Pri številnih bolnikih je opaziti mikroekemurozo, vendar se pojavijo tudi pogoste intenzivne krvavitve iz tkiva adenoma (v primeru poškodb zaradi manipulacije) ali krčne žile na območju vratu mehurja. S tvorjenjem strdkov je mogoče razviti tamponado mehurja, v katerem je nujna kirurgija potrebna. Pogosto vzrok krvavitve v adenoma prostate postane diagnostična ali terapevtska kateterizacija.. Kamni mehurja pri adenoma prostate lahko nastanejo zaradi stoječega urin ali migrirajo iz ledvic in sečil. Pri cistolitiaziji se klinična slika adenoma prostate dopolnjuje s ...
Pri moškem v 72 letih je prišlo do adenoma prostate. Obrnil se je k zdravniku, ko je bila bolezen že v zanemarjeni obliki, brez katetra pa ni bilo mogoče izprazniti mehurja. Takoj je ponudil operacijo za odstranitev adenoma, se je strinjal, odšel v bolnišnico, a ko sem videl post-kirurške bolnike, prestrašeni, izkazalo, da je z operacijo in je bil zaključen domov s katetrom. Po nasvetu urologu začel zdravljenje adenoma folk pravna sredstva: prvi dan posta mora jesti 0,5 skodelice orehov, v drugem - pol skodelice sončničnih semen, tretji dan od povprečja žarnice. Nadaljevati to zdravljenje prostate za tri mesece.. Moški je to zdravilo uporabljal in adenoma je izginila, a ker je imel nezdrav način življenja, se je nekaj let kasneje ponovno pojavil. Potem se je odločil, da bi adenoma zdravil z magnetom. Kupil je biokorrektorja iz podjetja Nevoton, vendar je bil učinek zdravljenja majhen. Potem je po mnenju zdravnika moški večkrat vzel magnet - od zvočnika radia. Poleg adenomom ...
Treatments & Remedies for Prostate Adenoma Prostate adenoma Adenoma epithelial tumor, usually benign, of similar structure to a gland. Tumor whose main characteristic is to have spaces lined with epithelium.
ADENOMA HIPOFISARIO PDF - En el presente trabajo se analiza el significado de la actividad proliferativa mediante inmunotinción con Ki en una serie de adenomas hipofisarios. Check
This page was last edited 02:09, 24 October 2017 by mahshid mir. Based on work by Jyostna Chouturi, Aarti Narayan and Prashanth Saddala and wikidoc user WikiBot ...
Pleomorphic adenoma • Pleurodont • Plica fimbriata • Polk E. Akers • Polymorphous low-grade adenocarcinoma • Polynoxylin • ... Canalicular adenoma • Canine tooth • Cantilever mechanics • Carbon dioxide laser • Caries vaccine • Carnassial • Case School of ...
Summary: Associated Cancers: colorectal and ovarian cancer; pilomatrixoma; medulloblastoma; pleomorphic adenomas; malignant ... pleomorphic adenomas, and malignant mesothelioma. While less is known about the exact mechanism of α-catenin, its presence in ... "The influence of 5-aminosalicylic acid on the progression of colorectal adenomas via the β-catenin signaling pathway". ...
Pleomorphic adenoma. References[edit]. *^ Witt, Robert L., ed. (2005). "Chapter 9 "Benign tumors, cysts, and tumor-like ... Though much less likely to occur than pleomorphic adenoma, Warthin's tumor is the second most common benign parotid tumor. ...
It is important that other tumors such as pleomorphic adenoma, basal cell adenoma, adenoid cystic carcinoma, and teratoma be ... "congenital pleomorphic adenoma"). A clinicopathologic, immunohistochemical and ultrastructural study of nine cases". Am J Surg ... It has previously been referred to as congenital basal cell adenoma, embryoma, or basaloid adenocarcinoma. It is an extremely ... Seifert, G.; Donath, K. (1997). "The congenital basal cell adenoma of salivary glands. Contribution to the differential ...
Contrary to pleomorphic adenoma, it is non recurrent. Pleomorphic adenoma Witt, Robert L., ed. (2005). "Chapter 9 "Benign ... Warthin's tumor is the second most common benign parotid tumor after pleomorphic adenoma, but its prevalence is steadily ...
PRKN Adenomas, multiple colorectal; 608456; MUTYH Adenomas, salivary gland pleomorphic; 181030; PLAG1 Adenomatous polyposis ... TCF4 Pituitary adenoma, ACTH-secreting; 219090; AIP Pituitary adenoma, growth hormone-secreting; 102200; AIP Pituitary adenoma ... EIF2B4 Leydig cell adenoma, somatic, with precocious puberty; 176410; LHCGR Leydig cell hypoplasia with hypergonadotropic ... SCN4A Parathyroid adenoma with cystic changes; 145001; HRPT2 Parathyroid carcinoma; 608266; HRPT2 Parietal foramina 1; 168500; ...
2008). "Tenascin and fibronectin expression in carcinoma ex pleomorphic adenoma". Appl. Immunohistochem. Mol. Morphol. 16 (1): ...
8, 17 and vimentin in pleomorphic adenoma of the salivary glands]". Arkh. Patol. 51 (10): 28-35. PMID 2482017. Eichbaum QG, ...
Lacrimal Gland Histology Pleomorphic adenoma of Krause's gland v t e. ...
They are morphologically identical to pleomorphic adenoma and have a female predilection. They range from developing deep ... The histopathology findings revealed: "small groups as well as scattered pleomorphic epithelial cells having hyperchromatic ... "the tumour had an expansive growing pattern and a few pleomorphic, atypical cells, and a rare mitotic activity."(Tural ...
The benign tumors include ceruminous adenoma, ceruminous pleomorphic adenoma, and ceruminous syringocystadenoma papilliferum. ...
1998). "Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas". Oncogene. 16 (7): 865 ...
The most common form of benign parotid neoplasms are pleomorphic adenomas and Warthin's tumor. The most common form of ...
Microscopically, its histology can be confused with an adenoid cystic carcinoma and a pleomorphic adenoma. Polymorphous low- ...
"PLAG1 gene alterations in salivary gland pleomorphic adenoma and carcinoma ex-pleomorphic adenoma: a combined study using ... Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is ... Voz ML, Agten NS, Van de Ven WJ, Kas K (2000). "PLAG1, the main translocation target in pleomorphic adenoma of the salivary ... in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter". Oncogene. 16 (11 ...
... and expression of HMGIC and MDM2 in a carcinoma ex pleomorphic adenoma". Am. J. Pathol. 160 (2): 433-40. doi:10.1016/S0002-9440 ... The same mutations that lead to pituitary adenomas in mice can be found in similar cancers in humans. Its presence is ... Fedele M, Pierantoni GM, Visone R, Fusco A (September 2006). "Critical role of the HMGA2 gene in pituitary adenomas". Cell ... "Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas". Oncogene. 21 (20): 3190-8. doi: ...
Other suggestions included ameloblastoma or a benign salivary mixed tumor (also known as a pleomorphic adenoma). In the 1980s, ...
Pleomorphic adenoma is seen to be a common benign neoplasm of the salivary gland and has an overall incidence of 54-68%. The ... The most common of these include pleomorphic adenoma (70% of tumors, of which 60% occur in females) and Warthin tumor (i.e. ... With various benign lesions, most commonly the pleomorphic adenoma, there is a risk of developing malignancy over time. As a ... The most common salivary gland neoplasms in children are hemangiomas, lymphatic malformations, and pleomorphic adenomas. ...
The promoter contains binding sites for Ikaros2, Nuclear Factor Y, and at least three binding sites for Pleomorphic adenoma ...
Tumors arising from other tissues may also produce a cartilage-like matrix, the best-known being pleomorphic adenoma of the ...
They included pleomorphic adenoma, myoepithelioma, myxoid neurofibroma, neurothekeoma (nerve sheath myxoma), chondroid ...
... an example of this is the pleomorphic adenoma of the salivary glands. Johnson AE (April 20, 2018). "Low - Grade Cartilage ...
2007). "Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 ... 2005). "Pleiomorphic adenoma gene-like-2, a zinc finger protein, transactivates the surfactant protein-C promoter". Am. J. ... "Entrez Gene: PLAGL2 pleiomorphic adenoma gene-like 2". Zheng H, Ying H, Wiedemeyer R, Yan H, Quayle SN, Ivanova EV, Paik JH, ...
... as well as pleomorphic adenoma. Metaplasia Dysplasia Barrett esophagus - a columnar cell metaplasia of squamous epithelium ...
Pleomorphic Adenoma Gene (PLAG) C2H2 Zinc Finger Transcription Factors 2 (ZF02) Vertebrate SMAD Family of Transcription Factors ...
... adenoma, liver cell MeSH C04.557.470.035.140 - adenoma, oxyphilic MeSH C04.557.470.035.155 - adenoma, pleomorphic MeSH C04.557. ... adenoma, bile duct MeSH C04.557.470.035.095 - adenoma, chromophobe MeSH C04.557.470.035.100 - adenoma, islet cell MeSH C04.557. ... adenoma MeSH C04.557.470.035.012 - acth-secreting pituitary adenoma MeSH C04.557.470.035.025 - adenoma, acidophil MeSH C04.557. ... adenoma, acidophil MeSH C04.557.465.625.650.075 - adenoma, basophil MeSH C04.557.465.625.650.095 - adenoma, chromophobe MeSH ...
Benign epithelial tumors Pleomorphic adenoma Warthin's tumor Myoepithelioma Basal cell adenoma Oncocytoma Canalicular adenoma ... Carcinoma ex pleomorphic adenoma Mammary analogue secretory carcinoma Carcinosarcoma Metastasizing pleomorphic adenoma Squamous ... Salivary gland tumours also known as mucous gland adenomas or neoplasms are tumours that form in the tissues of salivary glands ... "Mucous Gland Adenoma: The Spectrum of Growth Patterns and the Diagnostic Challenges". Advances in Anatomic Pathology. 27 (6): ...
... pleomorphic adenoma gene, zinc finger transcription factors, and an E2F-myc activator/cell cycle regulator. Many of them had ...
Myxoid leiomyosarcoma Myxoid liposarcoma Lipoblastoma Myxofibrosarcoma Myxoid cortical adenoma Pleomorphic adenoma ...
"Parapharyngeal Pleomorphic Adenoma" at the 3rd International Congress on Salivary Gland Diseases" in Geneva, Switzerland. He's ...
Pleomorphic anaplastic neuroblastoma, Pleomorphic xanthoastrocytoma, Primary central nervous system lymphoma, Sphenoid wing ... Pituitary adenomas ("pituitary tumours") are sometimes incorrectly referred to as a brain tumours.[68][69] This is perhaps ... Most pituitary adenomas can be removed surgically, often using a minimally invasive approach through the nasal cavity and skull ... base (trans-nasal, trans-sphenoidal approach). Large pituitary adenomas require a craniotomy (opening of the skull) for their ...
垂體腺瘤(英语:Pituitary adenoma):泌乳素瘤(英语:Prolactinoma) ... 多形性黃瘤細胞瘤(英语:Pleomorphic
Pleomorphic adenoma. *Mixed Müllerian tumor. *Mesoblastic nephroma. *Wilms' tumor. *Malignant rhabdoid tumour ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Pleomorphic carcinoma contains spindle cell and/or giant cell components, plus at least a 10% component of cells characteristic ... Adenomas/. adenocarcinomas. (8140-8429). Gastrointestinal. *tract: Linitis plastica. *Familial adenomatous polyposis. *pancreas ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
K. H. Kim: Pleomorphic adenoma of the trachea. In: Otolaryngology - Head and Neck Surgery. 123/2000, S. 147-148. ...
... tumor cells are pleomorphic/atypical, but resembling normal keratinocytes from prickle layer (large, polygonal, with abundant ... Adenoma sebaceum. *Metastatic carcinoma. *Giant-cell tumor of the tendon sheath. *Glomus tumor ... Poorly differentiated squamous carcinomas contain more pleomorphic cells and no keratinization.[32] ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Adenomyoma · Pleomorphic adenoma · Mixed Müllerian tumor · Mesoblastic nephroma · Wilms' tumor · Rhabdoid tumour · Clear-cell ... Chondroid lipoma · Intradermal spindle cell lipoma · Pleomorphic lipoma · Benign lipoblastomatosis · Spindle cell lipoma · ...
benign epithelial tumors (Pleomorphic adenoma, Warthin's tumor). ungrouped: Oncocytoma. Tongue. Leukoplakia · Rhabdomyoma ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Pleomorphic adenoma. *Mixed Müllerian tumor. *Mesoblastic nephroma. *Wilms' tumor. *Malignant rhabdoid tumour ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
多形性腺瘤(英语:Pleomorphic adenoma). *苗勒管混合瘤 ... 恶性纤维组织细胞瘤(英语:
Pituitary adenoma: Prolactinoma. *ACTH-secreting pituitary adenoma. *GH-secreting pituitary adenoma. *Craniopharyngioma ... Pleomorphic xanthoastrocytoma. *Subependymal giant cell astrocytoma. *Fibrillary astrocytoma. *Anaplastic astrocytoma. * ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Sebaceous adenoma. *Malignant: Acinic cell carcinoma. *Adenocarcinoma. *Adenoid cystic carcinoma. *Carcinoma ex pleomorphic ...
Plasmacytoma Plasmacytosis Pleomorphic T-cell lymphoma (non-mycosis fungoides CD30− pleomorphic small/medium-sized cutaneous T- ... Paget's disease of the breast Papillary eccrine adenoma (tubular apocrine adenoma) Papillary hidradenoma (hidradenoma ... Pleomorphic fibroma Pleomorphic lipoma Plexiform fibrohistiocytic tumor Porokeratotic eccrine ostial and dermal duct nevus ... Adenoma sebaceum Adult type of generalized eruption of cutaneous mastocytosis African cutaneous Kaposi sarcoma African ...
Though it is classified as a benign tumor, pleomorphic adenomas have the capacity to grow to large proportions and may undergo ... Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous ... Leonetti JP, Marzo SJ, Petruzzelli GJ, Herr B (September 2005). "Recurrent pleomorphic adenoma of the parotid gland". ... "Histopathology of pleomorphic adenoma in the parotid gland: a prospective unselected series of 100 cases". Laryngoscope. 111 ( ...
Salivary gland Pleomorphic adenoma Di Palma, S. (Jul 2013). "Carcinoma ex pleomorphic adenoma, with particular emphasis on ... Carcinoma ex pleomorphic adenoma (ca ex PA) is a type of cancer typically found in the parotid gland. It arises from the benign ... Carcinoma ex pleomorphic adenoma is diagnosed by examining it under the microscope with consideration of the individual history ... In approximately 75% of cases ca ex PAs arise in a pleomorphic adenoma that is apparent when the tumour is excised. In the ...
Metastasizing pleomorphic adenoma is 1 of these; the other 2 are carcinoma ex pleomorphic adenoma and true malignant mixed ... There are 3 main patterns of malignant change that occur in pleomorphic adenoma. ... Pathology of metastasizing pleomorphic adenoma. The image shows metastasizing pleomorphic adenoma of the skin on the lower ... Metastasising pleomorphic salivary adenoma: a rare case report of a massive untreated minor salivary gland pleomorphic adenoma ...
Metastasizing pleomorphic adenoma is a rarely detected form of clinic antity [2,3]. According to the World… ... Pleomorphic adenoma is the most common salivary gland tumor on the head and neck region [1]. ... Pleomorphic adenoma is the most common salivary gland tumor on the head and neck region [1]. Metastasizing pleomorphic adenoma ... of the metastazing pleomorphic adenoma is related with previous pleomorphic adenoma. ...
Fifty-two cases of pleomorphic adenoma of minor salivary gland origin and seventy-two cases of pleomorphic adenoma of major ... Fifty-two cases of pleomorphic adenoma of minor salivary gland origin and seventy-two cases of pleomorphic adenoma of major ... "Hyaline cells" in pleomorphic adenoma of salivary gland origin Oral Surg Oral Med Oral Pathol. 1981 Nov;52(5):506-12. doi: ...
A rare case of a benign pleomorphic adenoma is reported, arising in a parotid lymph node in a 52-year-old woman. Serial ... Takeda, Y., Suzuki, A. Benign pleomorphic adenoma arising in a parotid lymph node. Virchows Arch. A Path. Anat. and Histol. 396 ... Benign pleomorphic adenoma arising in a parotid lymph node. *Y. Takeda1. & ... A rare case of a benign pleomorphic adenoma is reported, arising in a parotid lymph node in a 52-year-old woman. Serial ...
The facial nerve provides motor innervation to the muscles of facial expression, scalp, stapedius, stylohyoideus and posterior belly of the digastric. It is sensory from the anterior 2/3 of the tongue (taste), external auditory meatus, soft palate and adjacent pharynx. It carries parasympathetic fibers which are secretomotor to the submaxillary, sublingual, lacrymal, nasal and palatine glands. It enters the substance of the parotid at the posterior border of the gland and immediately divides into a temporofacial and cervicofacial branch. Each branch subdivides into numerous nerves exiting the anterior borders of the gland to spread over the face. The marginal mandibular branch is variable, sometimes coming off the main trunk before the bifurcation. Notes ...
The facial nerve emerges at the inferior border of the pons (see brain anatomy), travels through the facial canal in the petrous portion of the temporal bone and emerges from the stylomastoid foramen. The foramen can be located by following the groove between the tympanic portion of the temporal bone and the mastoid process. The nerve is at 6:00 in relation to the ear canal. Notes ...
... pleomorphic adenoma or PA); it accounts for approximately 3-4% of all salivary gland n ... Carcinoma ex pleomorphic adenoma (CXPA) is a malignant epithelial neoplasm arising in a benign mixed tumor (i.e., ... Carcinoma ex pleomorphic adenoma (CXPA) is a malignant epithelial neoplasm arising in a benign mixed tumor (i.e., pleomorphic ... Carcinoma ex-pleomorphic adenoma of the nasal cavity: a report of two cases. J Laryngol Otol. 1995;109:677-9.PubMedCrossRef ...
A pleomorphic adenoma is a benign neoplasm that forms in the salivary gland. Although they start out benign they do have the ... While pleomorphic adenoma can occur at any age, they are most commonly diagnosed between the ages of 43 - 46. Pleomorphic ... A pleomorphic adenoma is a benign neoplasm that forms in the salivary gland. Although they start out benign they do have the ... Treatment of pleomorphic adenoma depends on the size, location and stage of the tumor. Also, if it is benign or malignant tumor ...
We report a rare case of pleomorphic adenoma arising from the lateral nasal wall. PATIENT AND METHOD: A 23year old woman ... AIM/BACKGROUND: We report a rare case of pleomorphic adenoma arising from the lateral nasal wall. PATIENT AND METHOD: A 23year ... The diagnosis, clinical behaviour and treatment of pleomorphic adenoma of the lateral nasal wall are discussed from a review of ... which are histological characteristics of pleomorphic adenoma. CONCLUSIONS: Her post-operative clinic visits were uneventful, ...
Pleomorphic adenoma. Image. Description. Pleomorphic adenoma (mixed tumor): A well circumscribed firm soft tissue enlargement ... Pleomorphic adenoma (mixed tumor): A Waters sinus radiograph of the previous patient. Note that the lesion has invaded the left ... Pleomorphic adenoma (mixed tumor): A firm well circumscribed soft tissue enlargement fills up the palatal vault. The lesion has ... Pleomorphic adenoma (mixed tumor): A microscopic image showing ducts lined by cuboidal cells, islands of epithelium, and loose ...
Pleomorphic Adenoma of the Parotid: Extracapsular Dissection Compared with Superficial Parotidectomy-A 10-Year Retrospective ... The authors carried out a retrospective cohort study of 198 patients with pleomorphic adenomas of the parotid gland. ... Extracapsular dissection may be considered the treatment of choice for pleomorphic adenomas located in the superficial portion ... rates and effectiveness of extracapsular dissection compared with superficial parotidectomy for pleomorphic adenomas of the ...
Conclusion: Metastatizing pleomorphic adenoma is a rare pathologic situation but, in case of swelling or lump appearance in ... Metastasizing pleomorphic adenomas has rarely been reported. No histologic or molecular parameters exist at the present time ... A 54-year-old woman had a superficial left parotidectomy with facial nerve preservation for pleomorphic adenoma. She developed ... patients with pleomorphic adenoma history, it should be taken in mind. ...
Keywords: pleomorphic adenoma, oral surgery, salivary gland diseases. Abstract. OBJECTIVE: The Pleomorphic Adenoma is the most ... Pleomorphic Adenoma versus Basal Cell Adenoma: An immunohistochemical analysis with b-catenin. Brazilian Dental Science 2014. ... the surgical technique choice for the pleomorphic adenoma may vary. The adenoma keeps developing if it is not completely ... Surgical resection of pleomorphic adenoma * Ricardo Eugenio Varela Ayres de Melo Coordinator of the Specialization Course in ...
A review of the FNA cytologic features of this case of chordoma and of 17 consecutive cases of pleomorphic adenoma found that ... Parapharyngeal chordoma: A diagnostic challenge and potential mimic of pleomorphic adenoma on fine-needle aspiration cytology. ... A review of the literature found no previous instances in which chordomas mimicked pleomorphic adenoma on FNA. However, since ... intensely metachromatic material led to an initial diagnosis of pleomorphic adenoma. Review of the patients prior pathology ...
Treatment for Pleomorphic Adenoma. by Lee Morgan; Updated September 30, 2017 Related Articles. *Exercise Tips for Developing ... A pleomorphic adenoma is a benign tumor in the salivary glands that appears as a firm and painless mass. In rare cases these ... The most common and effective treatment for pleomorphic adenoma is a complete surgical excision of the tumor itself, according ... The WJSO reports that studies have shown a 6 to 7 percent recurrence rate for patients with benign pleomorphic adenoma. ...
Pleomorphic Adenoma Treatment in Los Angeles CA. Dr. Larian is a renowned pleomorphic adenoma treatment surgeon in Los Angeles ...
Pleomorphic adenoma of the parotid gland.. Non-contrast studies -- Sagittal SE T1-weighted MR image reveals a well- ...
Tavarez on pleomorphic adenoma hard palate: You clearly have a thyroid problem, and this needs to be discussed in context of ... Pleomorphic (Definition) We use the term pleomorphic often in pathology; it literally means "many shapes". Pleomorphic cells in ... I ve pleomorphic adenoma in parotid gland.dr performed fnac..does fnac spread tumor cells..scared.size is 1.5cm.entire gland ... Spread not likely: Pleomorphic adenoma is benign and there is minimal risk of spread with a fine needle aspirate. Removal is ...
Pleomorphic adenomas are the most common salivary gland tumours. This case was donated to Radiopaedia.org by Radswiki.net ... MRI and PET images demonstrate a right parotid pleomorphic adenoma. ... MRI and PET images demonstrate a right parotid pleomorphic adenoma. Pleomorphic adenomas are the most common salivary gland ...
Pleomorphic adenoma of the parotid gland.. Non-contrast studies -- Coronal fat-suppressed FSE T2-weighted MR image reveals a ...
Harrie R.P., Kendall C.J. (2014) Case Study 43 Pleomorphic Adenoma of Lacrimal Gland. In: Clinical Ophthalmic Echography. ...
Schwannoma-like pleomorphic adenoma is a rare variant of the common benign salivary neoplasm, pleomorphic adenoma. This ... Schwannoma-like pleomorphic adenoma is a rare variant of the common benign salivary neoplasm, pleomorphic adenoma. This ... Schwannoma-Like Pleomorphic Adenoma: Two Cases and a Review of the Literature. *Stephen H. Roth. ORCID: orcid.org/0000-0001- ... Roth, S.H., Faquin, W.C., Gimenez, C. et al. Schwannoma-Like Pleomorphic Adenoma: Two Cases and a Review of the Literature. ...
Synopsis pleomorphic adenoma with extensive squamous metaplasia +/- keratin cyst formations squamous metaplasia, sometimes with ... Home , F. Pathology by regions , Head and neck , Head , Mouth - Oral cavity , Salivary glands , pleomorphic adenoma with ... pleomorphic adenoma with extensive squamous metaplasia +/- keratin cyst formations. * squamous metaplasia, sometimes with the ... Pleomorphic adenoma with extensive squamous metaplasia and keratin cyst formations in minor salivary gland: a case report. 2011 ...
Aims To investigate the clinical and imaging features of primary and recurrent lacrimal gland pleomorphic adenoma (LGPA), as ... Lacrimal gland pleomorphic adenoma and malignant epithelial tumours: clinical and imaging differences ... Lacrimal gland pleomorphic adenoma and malignant epithelial tumours: clinical and imaging differences ...
Adenocarcinoma, Lacrimal gland, Pleomorphic adenoma Persistent URL dx.doi.org/10.1111/j.1442-9071.2005.01123.x, hdl.handle.net/ ... A case of an in situ adenocarcinoma of the lacrimal gland that developed in a recurring pleomorphic adenoma is presented. Six ... Mensink, H.W, Mooy, C.M, & Paridaens, A.D.A. (2005). In situ adenocarcinoma ex pleomorphic adenoma of the lacrimal gland. ... After local excision of the in situ adenocarcinoma ex pleomorphic adenoma, the tumour has been in control for over 6 years. ...
... pleomorphic adenoma gene-like 2 (PLAGL2), is implicated in a variety of cancers including acute myeloid leukemia (AML), ... Pleomorphic adenoma gene-like 2 regulates expression of the p53 family member, p73, and induces cell cycle block and apoptosis ... The proto-oncogene, pleomorphic adenoma gene-like 2 (PLAGL2), is implicated in a variety of cancers including acute myeloid ...
A 76-year-old man with a carcinoma ex pleomorphic adenoma (case 2). A, Axial T2-weighted image (fast spin-echo: TR/TE, 4102/90 ... Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: Radiologic-Pathologic Correlation with MR Imaging Including Diffusion- ... Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: Radiologic-Pathologic Correlation with MR Imaging Including Diffusion- ... Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: Radiologic-Pathologic Correlation with MR Imaging Including Diffusion- ...
Tyrosine crystals in a parotid pleomorphic adenoma in a Vietnamese boat person. ... Tyrosine crystals in a parotid pleomorphic adenoma in a Vietnamese boat person. ...
  • It is also known as "Mixed tumor, salivary gland type", which refers to its dual origin from epithelial and myoepithelial elements as opposed to its pleomorphic appearance. (wikipedia.org)
  • Though it is classified as a benign tumor, pleomorphic adenomas have the capacity to grow to large proportions and may undergo malignant transformation, to form carcinoma ex-pleomorphic adenoma, a risk that increases with time (9.5% chance to convert into malignancy in 15 years). (wikipedia.org)
  • metastasizing pleomorphic adenoma (MPA), carcinoma ex pleomorphic adenoma , and true malignant mixed tumor (carcinosarcoma) . (medscape.com)
  • Metastasizing pleomorphic adenoma (the term currently preferred by the World Health Organization [WHO]) is also known as metastasizing benign pleomorphic adenoma, metastasizing benign mixed tumor, and metastasizing mixed tumor. (medscape.com)
  • It is worthwhile to note that the 2015 WHO classification of head and neck tumors considers metatsasizing pleomorphic adenoma as a malignant tumor of epithelial origin. (medscape.com)
  • Wermuth et al suggested that pulmonary metastasis of pleomorphic adenoma could arise from aspiration of tumor cells shed from salivary glands into the pharynx. (medscape.com)
  • Pleomorphic adenoma is the most common salivary gland tumor on the head and neck region [ 1 ]. (medium.com)
  • Pleomorphic adenoma is the most common type of salivary glad tumor and they are generally slow growing. (knowcancer.com)
  • Treatment of pleomorphic adenoma depends on the size, location and stage of the tumor. (knowcancer.com)
  • Pleomorphic adenoma (mixed tumor): A well circumscribed firm soft tissue enlargement of the posterior lateral hard palate. (uiowa.edu)
  • Pleomorphic adenoma (mixed tumor): A microscopic image showing ducts lined by cuboidal cells, islands of epithelium, and loose connective tissue staining basophilic (myoid). (uiowa.edu)
  • Pleomorphic adenoma (mixed tumor): High power microscopic image showing ducts lined by cuboidal epithelial cells. (uiowa.edu)
  • Pleomorphic adenoma (mixed tumor): A firm well circumscribed soft tissue enlargement fills up the palatal vault. (uiowa.edu)
  • Pleomorphic adenoma (mixed tumor): A Waters sinus radiograph of the previous patient. (uiowa.edu)
  • Pleomorphic adenoma constitutes the most common benign parotid gland tumor. (scirp.org)
  • CONCLUSION: The present study concludes that pleomorphic adenoma is a benign tumor with diverse characteristics and surgical technique choice depends on the lesion depth, as well as its extension and relation with the facial nerve. (pucrs.br)
  • A pleomorphic adenoma is a benign tumor in the salivary glands that appears as a firm and painless mass. (azcentral.com)
  • The most common and effective treatment for pleomorphic adenoma is a complete surgical excision of the tumor itself, according to the World Journal of Surgical Oncology (WJSO). (azcentral.com)
  • His board-certified team at the Center for Advanced Parotid & Facial Nerve Surgery provides effective parotid tumor removal, pleomorphic adenoma and parotitis treatment. (alivedirectory.com)
  • Pleomorphic cells in a tumor may tell of the genetic instability that's central to cancer, but the benign pleomorphic adenoma of the salivary glands merely has many different tissue types. (healthtap.com)
  • I have a small tumor behind ear.biopsy result came as benign salivary gland tumor,basal cell adenoma.surgery needed?is it urgent?can bcme cancerous? (healthtap.com)
  • A diagnosis of probable benign mixed cell tumor of the lacrimal gland was made, and an en bloc excision later confirmed this. (springer.com)
  • Pleomorphic adenoma, also called mixed tumor, is the most common benign tumor of the salivary glands that mostly occurs in the parotid or submandibular glands, but may also occur in the minor salivary glands that are distributed throughout the oral cavity. (scopemed.org)
  • Based on these findings, it was concluded that p53 and PCNA can favor the proliferative activity of pleomorphic adenomas, whereas bcl-2 probably doesonot effectively particípate in the pathogenesis of this tumor. (conicyt.cl)
  • Histopathological examination revealed well-demarcated tumor tissues showing typical histologic features of pleomorphic adenoma. (biomedcentral.com)
  • Carcinoma ex pleomorphic adenoma (CXPA), described as a rare malignant epithelial tumor arising from a pre-existing pleomorphic adenoma (PA), accounts for approximately 12% of all salivary gland malignancies and 6.2% of all PAs [ 1 ]. (biomedcentral.com)
  • Pathological diagnosis of the tumor was intrasellar salivary gland-like pleomorphic adenoma. (elsevier.com)
  • Pleomorphic Adenoma, also known as mixed tumor of the salivary gland , is related to salivary gland adenoma, pleomorphic and pleomorphic adenoma carcinoma . (malacards.org)
  • Pleomorphic adenoma (PA) is the most commonly found neoplasm amongst tumors of the major and minor salivary glands, originally called a mixed benign tumor in 1866 3-5 . (bvsalud.org)
  • Pleomorphic adenoma (also known as benign mixed tumor) is the most common tumor of the major salivary glands, and the most common benign tumor of the parotid glands (~75% of all benign salivary gland tumors). (blogspot.com)
  • Pleomorphic Adenomais a very common type of non-cancerous tumor also known as benign neoplasm. (naturalayurvedictreatment.com)
  • It is a Benign Mixed tumor (BMT's) type of salivary gland because of its pleomorphic appearance, characterized by neoplastic proliferation and having a malignant potentiality. (naturalayurvedictreatment.com)
  • Although it benign tumor Pleomorphic Adenoma but have the capacity to grow in large proportions and become malignant. (naturalayurvedictreatment.com)
  • The epidemiology of Pleomorphic Adenoma occurs in both men and women, but this tumor is usually occurs in adults between the age group of forty five and sixty. (naturalayurvedictreatment.com)
  • Tumor resection was accomplished through degloving and tumor histopathology analysis diagnosed pleomorphic adenoma. (arquivosdeorl.org.br)
  • Pathological anatomy exam showed an expressive development with poligonal cells of eosinophils cytoplasm and round and oval nuclei disposed in acinus and trabeculae, over a myxoid matrix and diagnosed as pleomorphic adenoma (mixed benign tumor). (arquivosdeorl.org.br)
  • Thus, in pleomorphic adenoma, Wnt is involved in tumor cell differentiation of peripheral columnar cells forming solid nests and small peripheral columnar cells forming duct-like structures. (elsevier.com)
  • Therefore, Wnt signaling through β-catenin pathway may be involved in the 'mixed' differentiation characteristic of pleomorphic adenoma although another pathway may also be possibly working in other parts of the tumor tissue. (elsevier.com)
  • The cytologic presentation of pleomporhic adenoma can mimic other carcinomas however, such as colloid carcinoma or possibly phyllodes tumor . (breast-cancer.ca)
  • Conclusion: Pleomorphic adenoma is a rare benign tumor of the sinonasal tract. (elsevier.com)
  • Although the most common tumor with bilateral synchronous or metachronous development is the Warthin tumor, pleomorphic adenomas have been diagnosed simultaneously as well. (mysciencework.com)
  • Pleomorphic adenoma is the commonest benign tumor involving the salivary glands. (wikidot.com)
  • The most common benign tumor is pleomorophic adenoma, and the most common malignant tumor is the mucoepidermoid carcinoma. (parotidsurgerymd.com)
  • Pleomorphic adenoma is, by far, the most common benign salivary gland tumor, accounting for as many as 80% of all such tumors. (parotidsurgerymd.com)
  • Pleomorphic adenoma is the most common tumor in these glands, even though almost half of the tumors found in the minor salivary glands are malignant. (parotidsurgerymd.com)
  • Only pleomorphic adenoma is a more common benign parotid tumor. (parotidsurgerymd.com)
  • Treatment of pleomorphic adenoma by modern treatment depends upon the size, stage and type of the salivary gland tumor. (drvikram.com)
  • Pleomorphic adenoma, the most common salivary gland tumor, is also known as benign mixed tumors (BMT's), because of its dual origin from epithelial and myoepithelial elements.It is the commonest of all salivary gland tumors constituting up to two-thirds of all salivary gland tumors. (henryford.com)
  • Demirag F, Topcu S, Kurul C, Memis L, Altinok T. Malignant pleomorphic adenoma (malignant mixed tumor) of the trachea: a case report and review of the literature. (iranpath.org)
  • Mucoepidermoid metaplasia in pleomorphic adenoma is very unusual and entails the need of a careful analysis of this tumor and its distinction from its malignant counterparts. (manipal.edu)
  • The terms "malignant mixed tumor" and "carcinoma arising in pleomorphic adenoma" have been used interchangeably. (jpatholtm.org)
  • The term carcinoma arising in pleomorphic adenoma refers to an epithelial malignancy in which remnants of benign pleomorphic adenoma (mixed tumor) matrix can be identified. (jpatholtm.org)
  • Background/purpose: Pleomorphic adenoma (PA) is the most common salivary gland tumor and the palate is the most common intraoral site for PA. (elsevier.com)
  • Though much less likely to occur than pleomorphic adenoma , Warthin's tumor is the second most common benign parotid tumor. (wikipedia.org)
  • Pleomorphic adenoma (PA) is a benign tumor of the salivary glands that has components of both epithelial and mesenchymal origin. (ijop.net)
  • Carcinoma ex pleomorphic adenoma (ca ex PA) is a type of cancer typically found in the parotid gland. (wikipedia.org)
  • Carcinoma ex pleomorphic adenoma is diagnosed by examining it under the microscope with consideration of the individual history. (wikipedia.org)
  • Some investigators hypothesize that there is an intermediate link in the transformation of pleomorphic adenoma into carcinoma ex pleomorphic adenoma. (medscape.com)
  • Gnepp DR, Brandwein-Gensler M, El-Naggar AK, Nagao T. Carcinoma ex pleomorphic adenoma. (springer.com)
  • Freeman SR, Sloan P, de Carpentier J. Carcinoma ex-pleomorphic adenoma of the nasal septum with adenoid cystic and squamous carcinomatous differentiation. (springer.com)
  • Carcinoma ex-pleomorphic adenoma of the nasal cavity: a report of two cases. (springer.com)
  • Ellis GL, Auclair PL. Carcinoma ex pleomorphic adenoma. (springer.com)
  • Carcinoma ex pleomorphic adenoma: pathologic analysis of 73 cases. (springer.com)
  • Carcinoma ex pleomorphic adenoma: a clinicopathologic review. (springer.com)
  • In rare cases these tumors can sometimes become malignant (carcinoma ex pleomorphic adenoma) and will grow rapidly, cause pain and could become life-threatening. (azcentral.com)
  • A 76-year-old man with a carcinoma ex pleomorphic adenoma (case 2). (ajnr.org)
  • To assess lymphatic vascular density (LVD) and lymph vessel endothelial proliferation in a series of carcinoma ex pleomorphic adenoma (CXPA) that represents the tumour in the different carcinogenesis phases and tumour progression. (bmj.com)
  • Purpose: We sought to identify genomic alterations (GAs) in salivary gland adenocarcinomas, not otherwise specified (NOS), salivary duct carcinomas (SDC), carcinoma ex pleomorphic adenoma (ca ex PA), and salivary carcinoma, NOS. (aacrjournals.org)
  • There is 1 clinical trial for salivary gland carcinoma ex pleomorphic adenoma, of which 1 is open and 0 are completed or closed. (mycancergenome.org)
  • Of the trial that contains salivary gland carcinoma ex pleomorphic adenoma as an inclusion criterion, 1 is phase 2 (1 open). (mycancergenome.org)
  • ERBB2 and HER2 are the most frequent gene inclusion criteria for salivary gland carcinoma ex pleomorphic adenoma clinical trials [ 3 ]. (mycancergenome.org)
  • Nanoparticle-based paclitaxel suspension and trastuzumab are the most common interventions in salivary gland carcinoma ex pleomorphic adenoma clinical trials. (mycancergenome.org)
  • article{Stodulski2007CarcinomaEP, title={[Carcinoma ex pleomorphic adenoma of major salivary glands--a clinicopathologic review]. (semanticscholar.org)
  • Biomarker analysis in carcinoma ex pleomorphic adenoma at an early phase of carcinomatous transformation. (semanticscholar.org)
  • Carcinoma ex benign pleomorphic adenoma of the parotid gland. (semanticscholar.org)
  • Carcinoma ex pleomorphic adenoma (CXPA): immunoprofile of the cells involved in carcinomatous progression. (semanticscholar.org)
  • Squamous cell carcinoma (SCC) as the malignant component of carcinoma ex pleomorphic adenoma (CXPA) occurring in upper lip is rare. (biomedcentral.com)
  • Kato H, Kanematsu M, Mizuta K, Ito Y, Hirose Y . Carcinoma ex pleomorphic adenoma of the parotid gland: radiologic-pathologic correlation with MR imaging including diffusion-weighted imaging. (blogspot.com)
  • Doctors remove this tumour because there is a very small risk that it can develop into a rare cancerous tumour called carcinoma ex-pleomorphic adenocarcinoma. (cancer.ca)
  • It may recur after excision or transform to a malignant neoplasm (carcinoma ex pleomorphic adenoma). (curofy.com)
  • Carcinoma ex pleomorphic adenoma (CXPA) is a carcinoma arising from a primary or recurrent benign pleomorphic adenoma. (plexusmd.com)
  • Surgery followed by radiotherapy should be considered as the standard care for a patient with carcinoma ex pleomorphic adenoma. (plexusmd.com)
  • Carcinoma ex pleomorphic adenoma (CXPA) is a rare salivary gland malignancy most often reported within the parotid gland. (pocketdentistry.com)
  • http://www.cxpacancer.com Thankfully, we have connected with a few wonderful people who've been impacted by carcinoma ex pleomorphic adenoma. (richardwhayes.com)
  • Akan H, Yildiz L, Unal R. Carcinoma ex pleomorphic adenoma of the minor salivary gland with pulmonary metastasis. (iranpath.org)
  • Objectives: It is hypothesized that carcinoma-ex-pleomorphic adenoma (Ca-ex-PA) is malignant from the beginning or is a malignant transformation of a recurrent or a long-standing pleomorphic adenoma (PA). (edu.au)
  • I was given 2-3 months to live before succumbing to the disease of carcinoma ex pleomorphic adenoma (a very rare head and neck cancer). (richardwhayes.com)
  • My cancer journey with Stage IVc Carcinoma Ex Pleomorphic Adenoma began on March 10, 2010. (richardwhayes.com)
  • Thankfully, I've connected with dozens of amazing people who've been impacted by carcinoma ex pleomorphic adenoma and related cancers. (richardwhayes.com)
  • Aims: To investigate the presence and distribution of the protein maspin in carcinoma ex pleomorphic adenoma (CXPA). (unicamp.br)
  • Intranasal mixed tumors (pleomorphic adenomas): a clinicopathologic study of 40 cases. (springer.com)
  • Matsuyama A, Hisaoka M, Hasimoto H. PLAG1 expression in mesenchymal tumors: an immunohistochemical study with special emphasis on the pathogenetical distinction between soft tissue myoepithelioma and pleomorphic adenoma of the salivary gland. (springer.com)
  • Merino MJ, LiVolsi VA. Pleomorphic adenomas of the parotid gland resembling mesenchymal tumors. (springer.com)
  • Pleomorphic adenomas originating from the minor salivary glands are rare in the para-pharyngeal space, although they are the most common benign tumors in this area followed by paragangliomas and the most common benign salivary gland tumors .In this paper we are reviewing a case of parapharyngeal pleo-morphic adenoma which was diagnosed transnasaly by endoscopic technique. (alliedacademies.org)
  • CONCLUSION: Tumors in all 3 reported cases of intrasellar salivary gland-like pleomorphic adenoma, including the present case, showed suprasellar extension and compressed optic chiasm that resulted in visual disturbance of the patients. (elsevier.com)
  • Differential diagnosis of intrasellar salivary gland-like pleomorphic adenomas should be considered in patients with calcified intrasellar tumors with suprasellar extension. (elsevier.com)
  • The change of name to "pleomorphic" adenoma was first suggested as recently as 1948, as this term describes the embryological basis for these tumors, which originate in the epithelial and connective tissue 3 . (bvsalud.org)
  • Pleomorphic Adenomas account for 60% to 80% of all tumors of the parotid gland. (naturalayurvedictreatment.com)
  • In this gland, 80% of the tumors is benign, and pleomorphic adenoma prevails, with an incidence ranging from 60.6 a 76.2% (2,8). (arquivosdeorl.org.br)
  • The fact that pleomorphic adenomas are classified as benign tumors should not overshadow the wide range of biological behaviors associated with these tumors. (plexusmd.com)
  • Pleomorphic adenomas are tumors mostly originating from salivary glands. (ac.ir)
  • Pleomorphic breast adenomas are so-named because they share similar morphological characteristics to the ' true ' pleomorphic adenomas, which are the most common benign tumors of the salivary glands, the parotid gland in particular. (breast-cancer.ca)
  • Although pleomorphic adenomas are benign parotid tumors, it has the potential to turn malignant. (parotidsurgerymd.com)
  • Primary pleomorphic adenomas of the respiratory tract are rare tumors. (elsevier.com)
  • Pleomorphic adenoma is the most common type of all benign and malignant salivary gland tumors, involving more frequently the parotid gland. (unicamp.br)
  • In a 2003 review by Nouraei et al, 42 cases of metastasizing pleomorphic adenoma were reported in the English-language literature between 1953 and 2005. (medscape.com)
  • It should be noted, however, that the exact number of cases of metastasizing pleomorphic adenoma has been a matter of controversy among reviewing authors. (medscape.com)
  • Tarjan G. Schwannoma including epithelial elements mimicking pleomorphic adenoma of the submandibular gland on fine-needle cytology: the first case report. (springer.com)
  • Aims To investigate the clinical and imaging features of primary and recurrent lacrimal gland pleomorphic adenoma (LGPA), as well as lacrimal gland malignant epithelial tumours (LGMET). (bmj.com)
  • Carcinosarcoma of the parotid gland with epithelial-myoepithelial carcinoma and pleomorphic sarcoma components. (semanticscholar.org)
  • Pleomorphic adenomas (PA) are the most common benign tumours of the lacrimal gland, which exhibit pleomorphism of epithelial components. (scitechnol.com)
  • Pleomorphic adenomas show a diverse histology , and may contain epithelial, myoepithelial and mesenchymal-type cells . (breast-cancer.ca)
  • In 8 cases of early CXPA (intracapsular and minimally invasive tumours), 8 of advanced CXPA (widely invasive tumours) and 10 of pleomorphic adenoma (PA) without malignant transformation, lymphatic vessels and proliferating cells were detected using the antibodies D2-40 and Ki-67 respectively. (bmj.com)
  • Preoperatively, a diagnosis of pleomorphic adenoma of the parotid gland metastasizing to the cervical lymph node was made, but postoperatively it was reported as CXPA adenoma of the parotid gland. (plexusmd.com)
  • Pleomorphic adenomas are the most common benign neoplasms of the parotid gland . (bvsalud.org)
  • Pleomorphic adenomas are the most common salivary gland tumours . (radiopaedia.org)
  • Pleomorphic adenomas (PA) are common benign tumours of the lacrimal gland . (scitechnol.com)
  • Of tumours arising within the minor salivary glands, pleomorphic adenoma is considered to be the most common benign variant. (pocketdentistry.com)
  • Pleomorphic adenoma is the most common salivary gland tumour and represents 60% to 70% of parotid tumours as well as 40% to 60% of the submandibular gland and minor salivary glands tumours [ 1 , 2 ]. (clinmedjournals.org)
  • Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous glandular cells along with myoepithelial components, having a malignant potentiality. (wikipedia.org)
  • A pleomorphic adenoma is a benign neoplasm that forms in the salivary gland. (knowcancer.com)
  • OBJECTIVE: The Pleomorphic Adenoma is the most common among benign neoplasm derived from salivary glands and it might suggest malignancy when there is some sort of fast growth, pain, facial nerve involvement and cervical adenopathy. (pucrs.br)
  • Schwannoma-like pleomorphic adenoma is a rare variant of the common benign salivary neoplasm, pleomorphic adenoma. (springer.com)
  • BACKGROUND Pleomorphic adenoma (PA) is the most common neoplasm of the major salivary glands. (semanticscholar.org)
  • 74 Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation. (malacards.org)
  • Pleomorphic adenoma is the most common neoplasm in major and minor salivary glands. (bvsalud.org)
  • Pleomorphic adenoma is the benign neoplasm more commonly found in great salivary glands, mainly in parotid. (arquivosdeorl.org.br)
  • Pleomorphic adenoma is the benign neoplasm more commonly found in greater salivary glands, mainly in parotid in 80% of the cases, and only 8% in lower salivary glands (1-4). (arquivosdeorl.org.br)
  • A ' pleomorphic ' adenoma is a very rare sub-type of breast adenoma , which is a proliferative neoplasm in some combination of glandular, fibrous, and fat tissues. (breast-cancer.ca)
  • Unfortunately pleomorphic adenoma has a fairly high rate of recurrence. (knowcancer.com)
  • The WJSO reports that studies have shown a 6 to 7 percent recurrence rate for patients with benign pleomorphic adenoma. (azcentral.com)
  • Objective: This study aimed to reveal diagnosis, management, and treatment outcome characteristics of sinonasal pleomorphic adenoma and to identify predictors for disease recurrence. (elsevier.com)
  • It is not yet understood why this happens, or which pleomorphic adenoma cells are prone to malignant transformation. (breast-cancer.ca)
  • Pleomorphic adenoma in the breast is a very rare and benign lesion with extremely rare cases of malignant transformation. (breast-cancer.ca)
  • METHODS: This cross-sectional study comparatively evaluated 21 cases of pleomorphic adenomas and 21 sections of regular oral mucosa from the files of an oral pathology department. (minervamedica.it)
  • The aim of this study is to report a case of an unusual minor salivary gland pleomorphic adenoma in the hard palate, describing the most important aspects of this pathology. (bvsalud.org)
  • It arises from the benign tumour pleomorphic adenoma. (wikipedia.org)
  • In approximately 75% of cases ca ex PAs arise in a pleomorphic adenoma that is apparent when the tumour is excised. (wikipedia.org)
  • After local excision of the in situ adenocarcinoma ex pleomorphic adenoma, the tumour has been in control for over 6 years. (eur.nl)
  • Pleomorphic adenoma may also be called a benign mixed tumour. (cancer.ca)
  • Pleomorphic adenomas: Post-operative radiotherapy is unnecessary following primary incomplete excision: A retrospective review. (pucrs.br)
  • Total surgical excision is the preferred treatment for pleomorphic adenomas. (alliedacademies.org)
  • AIM/BACKGROUND: We report a rare case of pleomorphic adenoma arising from the lateral nasal wall. (biomedsearch.com)
  • We report a rare case of pleomorphic adenoma that originated from the mucosal lining, just above the glottic area at the level of the laryngeal ventricle in a 55-year-old female patient. (ac.ir)
  • A rare case of pleomorphic adenoma with mucoepidermoid metaplasia in a middle aged female is reported here. (manipal.edu)
  • Bone remodelling on imaging may suggest a benign lacrimal gland pleomorphic adenoma (LGPA) rather than a malignant process. (springermedizin.de)
  • Orbital pleomorphic adenomas normally present as painless enlarging lesions. (scitechnol.com)
  • Small, low-grade lesions can be mistaken for pleomorphic adenomas. (blogspot.com)
  • The architectural patterns and cell formations in these lesions are highly varied, or ' pleomorphic ' so to speak. (breast-cancer.ca)
  • However, there is some history of malignant degeneration of pleomorphic adenomas occuring in other areas of the body, and for this reason even benign pleomorphic lesions are thought to contain a slightly higher risk for breast cancer development. (breast-cancer.ca)
  • Pleomorphic adenoma, anterior hard palate, salivary gland. (ijop.net)
  • We report the case of a 42-year old man who came with a complaint of a swelling in the anterior region of the hard palate and later diagnosed as pleomorphic adenoma based on histopathological examination. (ijop.net)
  • [ 12 ] Watson et al reported a fatal case of metastasizing pleomorphic salivary adenoma, in which a 61 year-old woman had a massive untreated minor salivary gland pleopmorphic adenoma (in the palatal vault) and concurrent ipsilateral cervical node metastases. (medscape.com)
  • A rare case of a benign pleomorphic adenoma is reported, arising in a parotid lymph node in a 52-year-old woman. (springer.com)
  • Pleomorphic Adenoma of the Lateral Nasal Wall-A case report. (biomedsearch.com)
  • Metastatizing pleomorphic adenoma is a rare pathologic situation but, in case of swelling or lump appearance in patients with pleomorphic adenoma history, it should be taken in mind. (scirp.org)
  • G. Mannelli, L. Rucci and O. Gallo, "Unusual Metastases from a Pleomorphic Adenoma of the Parotid Gland: A Case and Literature's Review," International Journal of Otolaryngology and Head & Neck Surgery , Vol. 2 No. 6, 2013, pp. 232-235. (scirp.org)
  • Pleomorphic Adenoma of the Tongue Base: Case Report and Review. (pucrs.br)
  • A review of the FNA cytologic features of this case of chordoma and of 17 consecutive cases of pleomorphic adenoma found that the presence of a more abundant, focally vacuolated cytoplasm favors chordoma over pleomorphic adenoma. (wiley.com)
  • Harrie R.P., Kendall C.J. (2014) Case Study 43 Pleomorphic Adenoma of Lacrimal Gland. (springer.com)
  • Lombardi M, Socciarelli F, Finin G, Leonardi A, Bartolazzi A. Schwannoma-like pleomorphic adenoma: a case report with review of the literature. (springer.com)
  • Pleomorphic adenoma with extensive squamous metaplasia and keratin cyst formations in minor salivary gland: a case report. (humpath.com)
  • A case of an in situ adenocarcinoma of the lacrimal gland that developed in a recurring pleomorphic adenoma is presented. (eur.nl)
  • The authors report a case of malignant pleomorphic adenocarcinoma, which was misdiagnosed clinico-radiologically as a benign LGPA. (springermedizin.de)
  • We hereby present a case report of pleomorphic adenoma with necrotic foci in the orbit of a 44-year-old lady and a review of current literature for focal necrosis in orbital pleomorphic adenoma. (scitechnol.com)
  • 4 ] described a case of painful eyelid swelling resembling dacryoadenitis that was biopsied to be pleomorphic adenoma with areas of necrosis. (scitechnol.com)
  • One case of a spontaneous infarction of a parotid pleomorphic adenoma in a 46-year-old lady is here described in which the cytopathologic findings, which were related to ischemic infarction, preceded fine-needle cytology sampling and mimicked malignancy. (ovid.com)
  • BACKGROUND AND IMPORTANCE: We present a rare case of a patient with intrasellar salivary gland-like pleomorphic adenoma and review the 2 previously reported cases of the clinical entity to identify their common clinical features. (elsevier.com)
  • To report a case of a giant pleomorphic adenoma that caused facial deformity and requested an access through degloving for its resection. (arquivosdeorl.org.br)
  • The target of this study is to report a case of nasal pleomorphic adenoma causing facial deformity in a 16-year-old female patient, due to the uncommon clinical condition observed which needed surgical resection through degloving because of size. (arquivosdeorl.org.br)
  • 2. Berenholz L, Kessler A, Segal S. Massive pleomorphic adenoma of the maxillary sinus: A case report. (ac.ir)
  • Palatal pleomorphic adenoma in a child with osteoid formation: report of case. (ac.ir)
  • 6. Mochinaga N, Yatsugi T, Tomokawa S. Pleomorphic adenoma of the breast: report of a case. (ac.ir)
  • 7. Dubey SP, Banerjee S, Ghosh LM, Roy S. Benign pleomorphic adenoma of the larynx: report of a case and review and analysis of 20 additional cases in the literature. (ac.ir)
  • 8. Sawatsubashi M, Tada K, Tokunaga O. Pleomorphic adenoma of the larynx: a case and review of the literature in Japan. (ac.ir)
  • 13. Ito A, Sone M, Kitamura Y, Fakuta S, Nakashima T, Yanagita N. A case of pleomorphic adenoma of the epiglottis.Bilateral vocal cord paralysis after YAG laser surgery.AnurisNasusLarymx 1997;24(3):303-7. (ac.ir)
  • Pleomorphic Adenoma of the Larynx: A Case Report', Iranian Journal of Otorhinolaryngology , 28(1), pp. 73-77. (ac.ir)
  • Synchronous pleomorphic adenomas of the major salivary glands: a case report. (mysciencework.com)
  • We report the case of a female patient who was diagnosed with pleomorphic adenomas in the right parotid and submandibular glands, concomitant with sialolithiasis affecting the submandibular gland. (mysciencework.com)
  • Gupta D, Agrawal S, Trivedi N, Tewari A. Pleomorphic adenoma of breast - a case report and distinction with metaplastic carcinoma. (sljol.info)
  • Manola M, Moscillo L, De Luca E, Lalinga AV, Possidente L (2019) Intraosseous Pleomorphic Adenoma of the Maxilla: A Case Report and Literature Review. (clinmedjournals.org)
  • The Authors describe a rare case of intraosseous pleomorphic adenoma occurring in the maxilla along with a complete review of literature. (clinmedjournals.org)
  • We present an extremely rare case of intraosseous pleomorphic adenoma occurring in the maxilla. (clinmedjournals.org)
  • We present a case of a giant pleomorphic adenoma in a 78-year-old man with a history of more than 30 years of a growing lesion in the parotid gland. (unicamp.br)
  • 1. Bill E, Becelli R, Iannetti G. A primary pleomorphic adenoma of the parapharyngeal space. (ac.ir)
  • Pleomorphic Adenomas of the Parapharyngeal Space - Descarga este documento en PDF. (duhnnae.com)
  • Occurrence of the pleomorphic adenoma in the parapharyngeal space is a rarity. (duhnnae.com)
  • Here, three giant pleomorphic adenomas of different sizes occupying the parapharyngeal space in three patients are reported. (duhnnae.com)
  • This study was undertaken to evaluate and concentrate on the recurrent pleomorphic adenomas (PAs) of the parapharyngeal space. (marmara.edu.tr)
  • Kapila K, Mathur S, Verma K. Schwannomas: a pitfall in the diagnosis of pleomorphic adenomas on fine-needle aspiration cytology. (springer.com)
  • The nodule was subjected to Fine Needle Aspiration Cytology (FNAC) and was found to be pleomorphic adenoma of minor salivary gland origin in upper lip. (scopemed.org)
  • Fine needle aspiration cytology from the mass was reported as pleomorphic adenoma. (wikidot.com)
  • the features were suggestive of pleomorphic adenoma (PA) (Figure 2 and Figure 3). (clinmedjournals.org)
  • The biopsy from the mass was suggestive of pleomorphic adenoma and was resected endoscopically. (elsevier.com)
  • The classical microscopic description was applied in 1874, observing a variety of cell types as the main characteristic of pleomorphic adenoma, not just between the different samples examined but also in different parts of the same sample 6 . (bvsalud.org)
  • Pleomorphic adenoma of the major salivary glands: diagnostic utility of FNAB and MRI. (blogspot.com)
  • Takeda Y, Shimono M. Pleomorphic adenoma with nuclear palisading of modified myoepithelial cells: histopathologic and immunohistochemical study. (springer.com)
  • B: 300 μm field of view (polymorphous mixture of spindle cells in a myxoid background showing a pleomorphic matrix with myoepithelial cells surrounding ductules and merging into stroma). (scitechnol.com)
  • A pleomorphic adenoma with myoepithelial differentiation is one in which there is a layer of myoepithelial cells present. (breast-cancer.ca)
  • Pleomorphic adenomas which are not ' differentiated ' by a layer of myoepithelial cells are thought to be of a higher risk for malignancy, though some of these sub-categories of breast cancer have only recently been recognized. (breast-cancer.ca)
  • Salivary gland Pleomorphic adenoma Di Palma, S. (Jul 2013). (wikipedia.org)
  • Polymorphous Low Grade Adenocarcinoma has a Consistent p63+/p40− Immunophenotype that Helps Distinguish it from Adenoid Cystic Carcinoma and Cellular Pleomorphic Adenoma. (ac.ir)
  • By definition, metastasizing pleomorphic adenoma is characterized by the presence of one or more foci of metastatic, histologically benign pleomorphic adenoma. (medscape.com)
  • In the reported cases, the distribution of metastasizing pleomorphic adenoma among males and females was almost statistically equal. (medscape.com)
  • The etiology of metastasizing pleomorphic adenoma is not clearly understood, but a number of theories have been put forward. (medscape.com)
  • Metastasizing pleomorphic adenoma is a rarely detected form of clinic antity [ 2 , 3 ]. (medium.com)
  • Metastasizing pleomorphic adenoma: a report of three casws. (ac.ir)
  • Typically, pleomorphic adenoma of major or minor salivary gland origin is present at the time of diagnosis, or the patient has a history of such adenoma, which may be recurrent. (medscape.com)
  • Fifty-two cases of pleomorphic adenoma of minor salivary gland origin and seventy-two cases of pleomorphic adenoma of major salivary gland origin were examined for the presence of hyaline cells (plasmacytoid cells). (nih.gov)
  • An unusual pleomorphic adenoma. (pucrs.br)
  • The presence of necrosis in a pleomorphic adenoma is highly unusual. (scitechnol.com)
  • Pleomorphic adenomas in nasal cavity are unusual and may be misdiagnosed because they have predominant myoepithelial cellularity and fewer myxoid stromata compared with those elsewhere. (elsevier.com)
  • Methods: This study comprised a retrospective review of data from seven patients with sinonasal pleomorphic adenoma who were treated by the authors at a tertiary medical center between January 2005 and May 2017. (elsevier.com)
  • As the prior history of chordoma was not available during the rapid onsite evaluation, the presence of bland epithelioid nonvacuolated cells and spindle cells intimately admixed with a fibrillary, intensely metachromatic material led to an initial diagnosis of pleomorphic adenoma. (wiley.com)
  • The authors carried out a retrospective cohort study of 198 patients with pleomorphic adenomas of the parotid gland. (hindawi.com)
  • This yielded histology of pleomorphic adenoma with cellular myoepithelial areas containing focal necrosis. (scitechnol.com)
  • MRI and PET images demonstrate a right parotid pleomorphic adenoma . (radiopaedia.org)
  • Giant pleomorphic adenoma of parotid gland. (bvsalud.org)
  • There are only few cases of giant pleomorphic adenomas reported in the literature . (bvsalud.org)
  • Purpose: To evaluate the role of radiation therapy in the management of recurrent pleomorphic adenoma of the parotid gland. (elsevier.com)
  • Methods and Materials: Between 1960 and 2004, 34 patients were treated with postoperative radiation therapy for recurrent pleomorphic adenoma of the parotid gland to a median dose of 5000 cGy (range, 4,500-6,000 cGy). (elsevier.com)
  • Conclusion: The use of postoperative radiation therapy leads to excellent long-term local control for the treatment of recurrent pleomorphic adenoma with acceptable late toxicity. (elsevier.com)
  • The proto-oncogene, pleomorphic adenoma gene-like 2 (PLAGL2), is implicated in a variety of cancers including acute myeloid leukemia (AML), malignant glioma, colon cancer, and lung adenocarcinoma. (biomedsearch.com)
  • Three diagnoses were of pleomorphic adenocarcinoma. (springermedizin.de)
  • Although pleomorphic adenomas most commonly occur in the parotid gland, it may also be encountered in the submandibular, lingual, and minor salivary glands. (parotidsurgerymd.com)
  • Depending on the lesion situs, size, depth, and volume, the surgical technique choice for the pleomorphic adenoma may vary. (pucrs.br)
  • The surgical management of an extensive pleomorphic adenoma arising within the deep lobe of the parotid gland is presented. (sahmriresearch.org)
  • Anderson, PJ & McLean, NR 1999, ' Management of a large pleomorphic adenoma of the parotid gland ', European Journal of Surgical Oncology , vol. 25, no. 3, pp. 330-331. (sahmriresearch.org)
  • Conclusion: Although rare, pleomorphic adenoma should be considered as a differential diagnosis for the swellings in the upper lip. (ac.ir)
  • There was associated expansion of the cavity with displacement of the nasal septum and thinning of the medial wall of the right maxillary antrum adjacent to it.The microscopic finding showed a lobular duct-like structure within a loose chondromyxoid stroma,which are histological characteristics of pleomorphic adenoma. (biomedsearch.com)
  • However there are certain histological characteristics in pleomorphic adenomas, which may raise suspicion of atypia and prompt further investigation. (scitechnol.com)
  • The diagnosis, clinical behaviour and treatment of pleomorphic adenoma of the lateral nasal wall are discussed from a review of the literature. (biomedsearch.com)
  • Methods: This study was performed on the basis of the clinical features of 10 well-documented reported cases of the upper lip pleomorphic adenomas from 1990 to 2012 which have been indexed in the PubMed. (ac.ir)