Adenoma, Chromophobe
Adenoma, Oxyphilic
A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
Carcinoma, Renal Cell
Pituitary Neoplasms
Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
Keratin-7
Adenoma, Pleomorphic
A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)
Adenoma, Villous
Adenocarcinoma, Clear Cell
An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)
Calbindin 1
Carcinoma, Papillary
Myelin and Lymphocyte-Associated Proteolipid Proteins
Adrenocortical Adenoma
A benign neoplasm of the ADRENAL CORTEX. It is characterized by a well-defined nodular lesion, usually less than 2.5 cm. Most adrenocortical adenomas are nonfunctional. The functional ones are yellow and contain LIPIDS. Depending on the cell type or cortical zone involved, they may produce ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE.
Birt-Hogg-Dube Syndrome
Parvalbumins
Immunohistochemistry
Chromosomes, Human, Pair 10
Tumor Markers, Biological
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Adaptor Protein Complex mu Subunits
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 2
Growth Hormone-Secreting Pituitary Adenoma
Colorectal Neoplasms
Colonic Polyps
ACTH-Secreting Pituitary Adenoma
Adaptor Protein Complex 1
Keratin-20
In Situ Hybridization, Fluorescence
Chromosomes, Human, Pair 6
Neprilysin
Enzyme that is a major constituent of kidney brush-border membranes and is also present to a lesser degree in the brain and other tissues. It preferentially catalyzes cleavage at the amino group of hydrophobic residues of the B-chain of insulin as well as opioid peptides and other biologically active peptides. The enzyme is inhibited primarily by EDTA, phosphoramidon, and thiorphan and is reactivated by zinc. Neprilysin is identical to common acute lymphoblastic leukemia antigen (CALLA Antigen), an important marker in the diagnosis of human acute lymphocytic leukemia. There is no relationship with CALLA PLANT.
Tissue Array Analysis
Adenoma, Acidophil
A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)
Calbindins
Prolactinoma
Kidney
Chromosomes, Human, Pair 17
Adenoma, Basophil
Chromosome Aberrations
Keratins
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Oligonucleotide Array Sequence Analysis
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Reverse Transcriptase Polymerase Chain Reaction
Immunoenzyme Techniques
Adenomatous Polyposis Coli
Neoplasm Proteins
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
Acromegaly
A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)
Cushing Syndrome
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
Genes, APC
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Prognosis
Membrane Proteins
Hyperparathyroidism
A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
Hyperplasia
Neoplasms, Multiple Primary
Pituitary ACTH Hypersecretion
Carcinoma
Hyperaldosteronism
Sphenoid Bone
An irregular unpaired bone situated at the SKULL BASE and wedged between the frontal, temporal, and occipital bones (FRONTAL BONE; TEMPORAL BONE; OCCIPITAL BONE). Sphenoid bone consists of a median body and three pairs of processes resembling a bat with spread wings. The body is hollowed out in its inferior to form two large cavities (SPHENOID SINUS).
Adrenocorticotropic Hormone
An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).
Pituitary Gland
Hyperparathyroidism, Primary
Precancerous Conditions
Sella Turcica
Heparin-induced thrombocytopenia: confirmation of diagnosis with in vitro methods. (1/47)
Profound thrombocytopenia developed in a patient during treatment with heparin for venous thrombosis. The platelet count increased toward normal when heparin administration was stopped, but fell abruptly when the drug was again given. Platelet aggregation occurred when heparin was added to the patient's platelet-rich plasma, or to normal platelets plus the patient's serum. This serum also effected release of 3H-serotonin from normal platelets. This pattern of aggregation was clearly different from that occasionally caused by heparin in a control population. The data is consistent with an effect of heparin on platelets, possibly mediated by on immune mechanism. (+info)Visual failure from pituitary and parasellar tumours occurring with favourable outcome in pregnant women. (2/47)
Very few cases have been reported of a successful outcome after relief by operation of severe visual failure from a pituitary or other parasellar tumour during the late stages of pregnancy. Two such cases are recorded here together with the obstetric features and follow-up studies of more than three years. Usually the deterioration of vi sion occurs in the latter half of the pregnancy and recovers rapidly after delivery, whether the onset of labour has occurred spontaneously or after induction. In subsequent pregnancies vision deteriorates at an earlier stage and becomes even more marked. Some cases are now occurring even in pregnancies induced by modern fertility drugs. The treatment of choice whenever vision is seriously threatened at any stage of pregnancy is a surgical attack on the pituitary, followed by suitable replacement therapy to ensure that the pregnancy continues. (+info)Subclinical Cushing's disease accompanied by malignant hypertension and diabetes mellitus. (3/47)
A 53-year-old woman was admitted because of hypertension and diabetes mellitus. Elevated diastolic blood pressure, hypertensive retinopathy and renal dysfunction indicated malignant hypertension. Adrenocorticotropic hormone (ACTH) and cortisol levels were high although there were no Cushingoid features. One mg dexamethasone administration decreased neither ACTH nor cortisol levels. Brain magnetic resonance imaging revealed a left pituitary tumor (7 mm x 6 mm). Upon removal, the tumor showed positive ACTH staining by immnohistochemistry, and was diagnosed as pituitary ACTH-secreting adenoma (Cushing's disease). Her blood pressure, renal function, blood glucose and hormone levels subsequently improved. Malignant hypertension and deteriorated diabetes mellitus may have been due to subclinical Cushing's disease. (+info)Sarcomatoid renal cell carcinoma with foci of chromophobe carcinoma. (4/47)
Both chromophobe carcinoma and sarcomatoid carcinoma of the kidney are rare. The former is characterized by a relatively good prognosis, while the latter is a highly aggressive tumor. Coexistence of the two components in one renal tumor, which has been reported only rarely, is therefore paradoxical. Both sarcomatoid and chromophobe renal carcinoma were diagnosed in a 52-year-old woman following nephrectomy and resection of metastases in the right lobe of the liver. She died of the disease two months after the first operation; only the sarcomatoid component of her tumor was seen in the liver metastasis and the recurrent carcinoma. Differences in phenotype, immunophenotype and DNA-ploidy patterns of the two components are reported. The intensive p53 staining observed only in the sarcomatoid area supports the role of the TP53 gene in the transformation of chromophobe renal carcinoma to sarcomatoid carcinoma. (+info)Moyamoya disease associated with pituitary adenoma--report of two cases. (5/47)
Moyamoya disease associated with prolactin (PRL)-producing pituitary adenomas occurred in two females with elevated blood PRL levels (285 and 120 ng/ml). Computed tomography revealed cystic tumors extending from the sella turcica to the suprasellar cistern. Carotid angiography demonstrated stenoses or obstructions of the bilateral internal carotid arteries at their end point and development of bilateral basal moyamoya vessels. Histological diagnosis in one case was PRL-producing chromophobe adenoma. No stigmata of neurofibromatosis or any history of irradiation was found. Compression of carotid arteries by the tumor was unlikely. These cases should therefore be classified as moyamoya disease accompanied by brain tumor, a very rare occurrence. The hypothalamic disturbance caused by moyamoya disease may have induced the hyperprolactinemia, resulting in secondary prolactinoma. (+info)Hypopituitarism caused by a melanoma of the pituitary gland. (6/47)
A clinical and pathological description is given of a case of panhypopituitarism caused by a melanoma of the pituitary gland. The possible origins of a melanoma in this site are discussed. (+info)Stroke after pituitary irradiation. (7/47)
BACKGROUND AND PURPOSE: Cranial irradiation may lead to accelerated atherosclerosis over several years. Stroke has been described after cranial irradiation administered for a number of conditions. However, pituitary irradiation has only rarely been associated with stroke. CASE DESCRIPTIONS: Two patients, 39 and 46 years of age, suffered strokes 13 and 20 years, respectively, after irradiation for pituitary tumors. Strokes were in the territories of small perforating arteries, but large vessels such as the carotid siphon and anterior cerebral arteries were also abnormal. Other risk factors for stroke were absent. CONCLUSIONS: It is suggested that pituitary irradiation increases the risk of subsequent stroke due to the known effects of ionizing radiation on vascular walls. (+info)Histologic coagulative tumor necrosis as a prognostic indicator of renal cell carcinoma aggressiveness. (8/47)
BACKGROUND: Prognostic markers for renal cell carcinoma (RCC), such as patient symptoms, tumor stage, tumor size, and tumor grade, are useful for determining appropriate follow-up and selecting patients for adjuvant therapy. Histologic coagulative tumor necrosis, also reported to be a prognostic marker for RCC, has not previously been extensively described or investigated. Hence, the objective of the current study was to characterize tumor necrosis as a prognostic feature of RCC. METHODS: The authors of the current study identified 3009 patients treated surgically for RCC between 1970 and 2002 from the Mayo Clinic Nephrectomy Registry (Rochester, MN). Associations of tumor necrosis with clinical, laboratory, and pathologic features were examined with chi-square, Fisher exact test, and Wilcoxon rank-sum tests. Cancer-specific survival was estimated with the Kaplan-Meier method, and associations with outcome were assessed with Cox proportional hazard models. RESULTS: Tumor necrosis was present in 690 of 2445 (28%) clear cell, 196 of 421 (47%) papillary, and 28 of 143 (20%) chromophobe RCCs. The risk ratio for death from RCC in patients with necrotic compared with non-necrotic tumors was 5.27 (95% confidence interval [CI]: 4.56-6.09; P < 0.001) for clear cell, 4.20 (CI: 1.65-10.68; P < 0.001) for chromophobe, and 1.49 (CI: 0.81-2.74; P = 0.199) for papillary RCC. The survival difference for clear cell RCC persisted even after multivariate adjustment for tumor stage, size, and grade (risk ratio 1.90; P < 0.001). CONCLUSIONS: Histologic coagulative tumor necrosis is an independent predictor of outcome for clear cell and chromophobe RCC, and it should be routinely reported and used in clinical assessment. (+info)Keywords bone + head + calvarium + chromophobe adenoma | PEIR Digital Library
Re: Hales method for colloidal iron
00004710 | PEIR Digital Library
Womens Healthcare - Bayer - Bayer Zydus Pharma
Neurology Medicine
Chromophobe cell - Wikipedia
Case 124 --Neuropathology Case
Nonfunctioning pituitary adenomas: association of Ki-67 and HMGA-1 labeling indices with residual tumor growth | SpringerLink
Massive reduction of tumour load and normalisation of hyperprolactinaemia after high dose cabergoline in metastasised...
Macroprolactinomas and Nonfunctioning Pituitary Adenomas and Pregnancy Outcomes - Nuffield Department of Population Health
Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma,...
Clinical manifestations and diagnosis of gonadotroph and other clinically nonfunctioning pituitary adenomas
Calcium Homeostasis in Acromegaly: Effect of Surgical/Medical Treatment and Comparison With Nonfunctioning Pituitary Tumors -...
Arterial Spin-Labeled Perfusion Imaging Reflects Vascular Density in Nonfunctioning Pituitary Macroadenomas | American Journal...
RCC Chromophobe | Cancer Survivors Network
nonfunctioning pituitary tumor drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
A Case of Nonfunctioning Pituitary Carcinoma That Responded to Temozolomide Treatment
ITS BEEN AWHILE | Cancer Survivors Network
Bottle Opener - Man, Woman, Geek
- GriffonCo 3D Printed Miniatures & Gifts
Magnetic Bottle Opener - Can We Play DND Now?
- GriffonCo 3D Printed Miniatures & Gifts
Silent corticotroph adenoma with multiple cysts: Pars intermedia tumor?<...
Browse In Striae, Immunostaining, Immunohistochemistry | EDM Case Reports
A mutation and expression analysis of the oncogene BRAF in pituitary adenomas | Archivio Istituzionale della Ricerca
JCM | Free Full-Text | Results of Treatment with Modern Fractionated Radiotherapy, Contemporary Stereotactic Radiosurgery, and...
Preoperative renal tumor subtype differentiation is definitely important for radiology and - Comparison of the Cancer Gene...
Gene expression changes in subcutaneous adipose tissue due to Cushings disease. | mrc2
Corneal and lenticular pigmentation following long term chlorpromazine therapy and its significance in causing visual defects. ...
Cushings Disease in a Patient With a Nonfunctioning Pituitary Tumor: Spontaneous Development and Remission | JAMA Internal...
Renal (Kidney) Cancer
Surface Inspection Software | Cognex Corp. | New Products | Apr 2010 | Photonics Spectra
Strabismus - Pathways.org
Chromophobe renal cell carcinoma with sarcomatoid differentiation<...
Chromophobe renal cell carcinoma
Chromophobe renal cell carcinoma
Chromophobe Renal Cell Carcinoma: A Clinicopathologic Study of 203 Tumors in 200 Patients With Primary Resection at a Single...
The somatic genomic landscape of chromophobe renal cell carcinoma<...
Comprehensive review of visual defects reported with topiramate | OPTH
Chromophobe renal cell carcinoma Datasets | BioGPS
Neil Alouch, MD | Office of the President | Creighton University
Galactorrhoea (High Prolactin)
PuRe Publikationen | Max-Planck-Institut für molekulare Genetik
Chromophobe renal cell carcinoma with prolonged response to targeted therapy: a case report | Journal of Medical Case Reports |...
Localized chromophobe renal cell carcinoma: preoperative imaging judgment and laparoscopic simple enucleation for treatment |...
Universal Pharmacy: Keflex for mrsa infections new pharmacy
Oncology Times Supplement October 25, 2016 Page 12
Pituitary Tumors - Causes, Symptoms, Diagnosis, Treatment
What is the prognosis for a pituitary tumor? | Pituitary Tumor - Sharecare
Pituitary Tumors Resources - Navigating Care
Galactorrhea (Aftercare Instructions) - What You Need to Know
Cranial Nerve Testing | almostadoctor
What is the treatment for a Pituitary Tumour? | Pituitary Tumors
After 9 months - AF arrives | DailyStrength
Hal0 2 Autoupdate - Xbox Lives Major Nelson
List of MeSH codes (C04)
... adenoma, bile duct MeSH C04.557.470.035.095 - adenoma, chromophobe MeSH C04.557.470.035.100 - adenoma, islet cell MeSH C04.557. ... adenoma, acidophil MeSH C04.557.465.625.650.075 - adenoma, basophil MeSH C04.557.465.625.650.095 - adenoma, chromophobe MeSH ... adenoma, acidophil MeSH C04.557.580.625.650.075 - adenoma, basophil MeSH C04.557.580.625.650.095 - adenoma, chromophobe MeSH ... adenoma MeSH C04.557.470.035.012 - acth-secreting pituitary adenoma MeSH C04.557.470.035.025 - adenoma, acidophil MeSH C04.557. ...
International Classification of Diseases for Oncology
M8270/0 Chromophobe adenoma (C75.1) M8270/3 Chromophobe carcinoma (C75.1) Chromophobe adenocarcinoma (M8271/0) Prolactinoma ( ... Black adenoma Pigmented adenoma M8373/0 Adrenal cortical adenoma, clear cell (C74.0) M8374/0 Adrenal cortical adenoma, ... Oxyphilic adenoma Oncocytic adenoma Oncocytoma Hurthle cell adenoma (C73.9) Hurthle cell tumor Follicular adenoma, oxyphilic ... NOS Pick tubular adenoma Sertoli cell adenoma Tubular androblastoma, NOS Testicular adenoma M8640/3 Sertoli cell carcinoma (C62 ...
Kidney cancer
... and renal adenoma. People with suspected kidney cancer should also have their kidney function evaluated to help determine ... Clear cell RCC Multilocular clear cell RCC Papillary RCC Chromophobe RCC Carcinoma of the collecting ducts of Bellini Renal ...
Cancer syndrome
Tumors with increased risk in this disorder are colorectal cancer, gastric adenomas and duodenal adenomas. Nevoid basal cell ... renal cell carcinoma of chromophobe, hybrid oncocytic, or oncocytoma histology; sebaceous carcinoma; and sex cord tumors with ... An individual with this disease will have hundreds to thousands of benign adenomas throughout their colon, which will in most ... Other tumors increased in frequency include; osteomas, adrenal adenomas and carcinomas, thyroid tumors and desmoid tumors. The ...
Birt-Hogg-Dubé syndrome
Hybrid oncocytoma/chromophobe carcinoma, found in 50% of cases, is the most commonly found cancer, followed by chromophobe ... parathyroid adenomas, flecked chorioretinopathy, neurothekeoma, meningiomas, angiofibromas of the face, trichoblastomas, ... People over 20 years of age with BHD have an increased risk of developing slow-growing kidney tumors (chromophobe renal ... Renal tumors can manifest as multiple types of renal cell carcinoma, but certain pathological subtypes (including chromophobe, ...
Anterior pituitary
A third type of pituitary adenoma secretes excess ACTH, which in turn, causes an excess of cortisol to be secreted and is the ... The pars distalis contains two types of cells, including chromophobe cells and chromophil cells. The chromophils can be further ... This hypersecretion often results in the formation of a pituitary adenoma (tumour), which are benign apart from a tiny fraction ... For example, acromegaly results from excessive secretion of growth hormone (GH) often being released by a pituitary adenoma. ...
List of OMIM disorder codes
TCF4 Pituitary adenoma, ACTH-secreting; 219090; AIP Pituitary adenoma, growth hormone-secreting; 102200; AIP Pituitary adenoma ... chromophobe, somatic; 144700; FLCN Renal cell carcinoma; 144700; DIRC2 Renal cell carcinoma; 144700; HNF1A Renal cell carcinoma ... PRKN Adenomas, multiple colorectal; 608456; MUTYH Adenomas, salivary gland pleomorphic; 181030; PLAG1 Adenomatous polyposis ... EIF2B4 Leydig cell adenoma, somatic, with precocious puberty; 176410; LHCGR Leydig cell hypoplasia with hypergonadotropic ...
Papillary renal cell carcinoma
March 2020). "Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor ... PRCC is generally heterogeneous with areas of necrosis and hemorrhage compared to chromophobe RCC. Solid, small PRCC tumors (. ...
Renal Cell Carcinoma Guidelines: Guidelines Summary, Diagnosis and Staging, Management of Stage I Renal Mass
H and E, high power of a chromophobe RCC composed of cells with clear, reticular cytoplasm and some with eosinophilic cytoplasm ... The maximum size of papillary adenoma was 5 mm but is now ≤15 mm in its largest dimension. ... The main prognostic factors in chromophobe RCC are tumor stage, the presence of necrosis, a sarcomatoid and/or rhabdoid ...
Renal Cell Carcinoma Guidelines: Guidelines Summary, Diagnosis and Staging, Management of Stage I Renal Mass
H and E, high power of a chromophobe RCC composed of cells with clear, reticular cytoplasm and some with eosinophilic cytoplasm ... The maximum size of papillary adenoma was 5 mm but is now ≤15 mm in its largest dimension. ... The main prognostic factors in chromophobe RCC are tumor stage, the presence of necrosis, a sarcomatoid and/or rhabdoid ...
HuGE Navigator|HuGE Literature Finder|PHGKB
No article was found for Adenoma, Chromophobe and GNAS[original query]. File Formats Help:. How do I view different file ...
Pituitary Tumors: Background, Pathophysiology, Epidemiology
These techniques have identified hormonal production in many chromophobe adenomas, enabling pathologists to identify hormones ... AIP mutation in pituitary adenomas in the 18th century and today. N Engl J Med. 2011 Jan 6. 364(1):43-50. [QxMD MEDLINE Link]. ... Treatment of pituitary adenomas by fractionated stereotactic radiotherapy: a prospective study of 110 patients. Int J Radiat ... Castinetti F, Régis J, Dufour H, Brue T. Role of stereotactic radiosurgery in the management of pituitary adenomas. Nat Rev ...
IMSEAR at SEARO: Search
1 Adenoma, Chromophobe --complications. *1 Adult. *1 Brain Neoplasms --complications. *1 Cerebral Hemorrhage --etiology ...
IMSEAR at SEARO: Search
1 Adenoma, Chromophobe. *1 Adult. *1 Child. *1 Female. *1 Humans. *1 Male ...
Code System Concept
Chromophobe tumor (morphologic abnormality) {253009008 , SNOMED-CT } Functioning endocrine tumor (morphologic abnormality) { ... Adenoma AND/OR adenocarcinoma (morphologic abnormality) {115215004 , SNOMED-CT } Download Relationships Other Relationships No ...
Birt-Hogg-Dube Syndrome (BHDS): Background, Pathophysiology, Etiology of BHDS
... most commonly hybrid oncocytic tumors with features of chromophobe renal carcinoma (50%), followed by chromophobe renal cancer ... Chung JY, Ramos-Caro FA, Beers B, Ford MJ, Flowers F. Multiple lipomas, angiolipomas, and parathyroid adenomas in a patient ... Other, less commonly associated features include a large connective-tissue nevus, parathyroid adenomas, flecked ...
Birt-Hogg-Dube Syndrome (BHDS): Background, Pathophysiology, Etiology of BHDS
... most commonly hybrid oncocytic tumors with features of chromophobe renal carcinoma (50%), followed by chromophobe renal cancer ... Chung JY, Ramos-Caro FA, Beers B, Ford MJ, Flowers F. Multiple lipomas, angiolipomas, and parathyroid adenomas in a patient ... Other, less commonly associated features include a large connective-tissue nevus, parathyroid adenomas, flecked ...
HuGE Navigator|Genopedia|PHGKB
Adenoma, Acidophil 1 0 Adenoma, Chromophobe 1 0 Growth Hormone-Secreting Pituitary Adenoma 1 0 ...
IMSEAR at SEARO: A clinico-pathologic study of pituitary adenomas.
... lactotroph adenomas). Tumours in group II were chromophobe, acidophil, basophil or mixed adenomas with varying number of ... A clinico-pathologic study of pituitary adenomas.. ผู้แต่ง/ผู้ร่วมงาน: Sarkar, C. Roy, S. Kochupillai, N. Gupta, N. Tandon, P N ... lactotroph adenomas) and ACTH in all tumours from patients with Cushing's syndrome (corticotroph adenomas). It was observed, ... Thus growth hormone was demonstrated in all tumours from patients with acromegaly (somatotroph adenomas), prolactin in all
Pituitary Gland Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Secretory adenomas are typically monoclonal--that is, they secrete a single hormone. Approximately 1 to 2% of adenomas secrete ... In general, acidophilic cells contain polypeptide hormones, basophilic cells contain glycoprotein hormones, and chromophobes ... GH-secreting adenomas are next most common adenomas, followed by adrenocorticotropic hormone (ACTH)-secreting tumors and ... 21] The vast majority originate in the adenohypophysis and are typically nonsecretory benign adenomas. These adenomas ...
IMSEAR at SEARO: Search
1 Adenoma, Chromophobe --complications. *1 Brain Neoplasms --complications. *1 Cerebral Hemorrhage --etiology ...
IMSEAR at SEARO: Search
1 Adenoma, Chromophobe --complications. *1 Adolescent. *1 Brain Diseases --pathology. *1 Brain Neoplasms --blood supply ...
IMSEAR at SEARO: Browsing DSpace
Chromophobe adenomas.. Ramamurthi, B. 1-Dec-1970. Chronic subdural hematoma.. Kalyanaraman, S; Ramamurthi, B; Ramamoorthi, K. ...
IMSEAR at SEARO: Search
1 Adenoma, Chromophobe --complications. *1 Adolescent. *1 Brain Diseases --pathology. *1 Brain Neoplasms --blood supply ...
Pituitary Gland Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Secretory adenomas are typically monoclonal--that is, they secrete a single hormone. Approximately 1 to 2% of adenomas secrete ... In general, acidophilic cells contain polypeptide hormones, basophilic cells contain glycoprotein hormones, and chromophobes ... GH-secreting adenomas are next most common adenomas, followed by adrenocorticotropic hormone (ACTH)-secreting tumors and ... 21] The vast majority originate in the adenohypophysis and are typically nonsecretory benign adenomas. These adenomas ...
HuGE Navigator|Phenopedia|PHGKB
2 genes has been reported with Adenoma, Chromophobe [Click to re-sort the table] ...
Pituitary Tumors: Background, Pathophysiology, Epidemiology
These techniques have identified hormonal production in many chromophobe adenomas, enabling pathologists to identify hormones ... AIP mutation in pituitary adenomas in the 18th century and today. N Engl J Med. 2011 Jan 6. 364(1):43-50. [QxMD MEDLINE Link]. ... Treatment of pituitary adenomas by fractionated stereotactic radiotherapy: a prospective study of 110 patients. Int J Radiat ... Castinetti F, Régis J, Dufour H, Brue T. Role of stereotactic radiosurgery in the management of pituitary adenomas. Nat Rev ...
HuGE Navigator|HuGE Literature Finder|PHGKB
No article was found for Adenoma, Chromophobe and GNAI2[original query]. File Formats Help:. How do I view different file ...
CraniopharyngiomaPapillary adenomaOncocytomaTumorBenignDiagnosesBasophilsOptic ChiasmSecretoryEosinophilicSyndromeCharacteristicsFactorsRareGrowthSurgeryPapillaryPituitary adenomasRenalCarcinomaHepatocellularHemorrhageTypeCellsAcidophilNeoplasmsPapillaryPituitary glandTumorsMetanephric adenomaProlactinCraniopharyngiomaMetastaticTranssphenoidal SurgeryMucinousOncocyticEpithelialDescriptorCarcinomaSerousClinicalResectionProlactinomasOperativeMarkerApproachSurgicalPatientsTreatmentShowsCancerGiantCasesAnalysisLowerControl
Craniopharyngioma1
- Primary intracranial tumors causing DI in dogs and cats include craniopharyngioma, pituitary chromophobe adenoma, and pituitary chromophobe adenocarcinoma and metastatic tumors include metastatic mammary carcinoma, lymphoma, malignant melanoma, and pancreatic carcinoma. (vin.com)
Papillary adenoma2
- The maximum size of papillary adenoma was 5 mm but is now ≤15 mm in its largest dimension. (medscape.com)
- 11 ] In the upcoming 4th edition of the World Health Organization (WHO) Classification of Tumors of the Urinary System and Male Genital Organs, tumor size using 1.5 cm as a cutoff will be proposed to distinguish renal papillary adenoma from papillary renal cell carcinoma, though it is unclear if the tumor size should be based on fresh, postfixation, or microscopic measurement. (jcancer.org)
Oncocytoma7
- As a result of variations in its classic appearance, difficulty in standardizing diagnostic criteria, and entities that mimic oncocytoma, such as eosinophilic variant chromophobe renal cell carcinoma (RCC) and succinate dehydrogenase-deficient RCC, pathologic diagnosis remains a challenge. (medscape.com)
- 5] The differential diagnosis of oncocytoma includes other neoplasms with eosinophilic or oncocytic cytoplasm and primarily chromophobe RCC, as well as clear cell RCC with eosinophilic cytoplasm-an oncocytic variant of papillary RCC. (medscape.com)
- Oncocytosis is a rare condition characterized by multiple oncocytic tumors with histologic features, including renal oncocytoma, hybrid oncocytic tumor, and, occasionally, chromophobe RCC. (medscape.com)
- With more than 95% confidence, the nested pattern, myxoid stroma, granular cytoplasm, and round nuclei are likely indicative of renal oncocytoma, whereas varying nuclear size, raisinoid nuclei, and reticular cytoplasm indicate a higher likelihood of chromophobe RCC. (medscape.com)
- Some growths in the kidney are not cancerous, such as renal adenoma, oncocytoma and angiomyolipoma. (uchicagomedicine.org)
- Multiple or bilateral renal carcinomas have been reported in association with this syndrome, most commonly hybrid oncocytic tumors with features of chromophobe renal carcinoma (50%), followed by chromophobe renal cancer, clear cell renal carcinoma, and renal oncocytoma. (medscape.com)
- Liu Q, Cornejo KM, Cheng L, Hutchinson L, Wang M, Zhang S, Tomaszewicz K, Cosar EF, Woda BA, Jiang Z. Next-Generation Sequencing to Detect Deletion of RB1 and ERBB4 Genes in Chromophobe Renal Cell Carcinoma: A Potential Role in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma. (umassmed.edu)
Tumor5
- The main prognostic factors in chromophobe RCC are tumor stage, the presence of necrosis, a sarcomatoid and/or rhabdoid component, and small vessel invasion. (medscape.com)
- analysis revealed that posterior lobe enhancement occurred 9.8 ± 1.5 sec (mean ± SEM) before the anterior lobe in healthy subjects, whereas tumor enhancement occurred significantly before the anterior lobe but only slightly before the posterior lobe in patients with adenomas. (1library.net)
- DICER1 tumor predisposition (DICER1) is characterized by an increased risk for pleuropulmonary blastoma (PPB), pulmonary cysts, thyroid gland neoplasia (multinodular goiter, adenomas, and/or thyroid cancer), ovarian tumors (Sertoli-Leydig cell tumor, gynandroblastoma, and sarcoma), and cystic nephroma. (nih.gov)
- Renal adenoma - Renal adenomas are the most common form of benign, solid kidney tumor, and are typically small, low-grade growths. (austincyberknife.com)
- A partir de la TAC se descubren las bullas pulmonares, y otro tumor de las mismas características en otro riñón. (bhdsyndrome.org)
Benign1
- Papillary adenomas are also benign renal neoplasms, but they arise from the renal tubular epithelium and almost always are located within the cortex. (medscape.com)
Diagnoses1
- Radiologically, papillary RCC or chromophobe RCC were considered as differential diagnoses. (researchsquare.com)
Basophils2
- Three such types of cells exist in the anterior pituitary gland: acidophils, basophils, and chromophobes. (thefreedictionary.com)
- Secretory cells in the adenohypophysis are often subdivided into chromophils (acidophils, basophils) and chromophobes based on interaction of the secretory granules with pH-dependent histochemical stain. (msdvetmanual.com)
Optic Chiasm1
- Suprasellar extension of the pituitary adenoma causes compression of the optic chiasm, resulting in the gradual onset of superior bitemporal quadrantopia that may progress to complete bitemporal hemianopsia (see Plate 1-11). (pediagenosis.com)
Secretory1
- Effectiveness of transsphenoidal surgery is assessed by the findings on postoperative MRI (typically performed 3 months after surgery) and by blood levels of adenoma secretory products that may have been increased before surgery (e.g., α -subunit of glycoprotein hormones). (pediagenosis.com)
Eosinophilic1
- Tumors resembling chromophobe adenomas of the pituitary gland with eosinophilic granulation on tetrachrome staining. (mhmedical.com)
Syndrome2
- G-protein abnormalities, ras gene mutations, p53 gene deletions, mutations, and rearrangements, and the association of pituitary tumors with the syndrome of multiple endocrine neoplasia have been described and are involved in the development of adenomas in the pituitary gland. (medscape.com)
- Type III = Forbes-Albright Syndrome: AGS caused by chromophobe prolactin-producing adenoma of the pituitary. (mhmedical.com)
Characteristics1
- PURPOSE: To measure and evaluate the temporal enhancement characteristics of the normal pituitary gland and pituitary adenoma. (1library.net)
Factors1
- Pituitary adenomas, with a few exceptions, are not under the control of hypothalamic releasing factors. (medscape.com)
Rare1
- Chromophobe RCC is a relatively rare type, with pale, large cells. (mountsinai.org)
Growth1
- [ 4 ] Nonfunctioning adenomas are associated with hypermethylation of p16 prolactinomas, and corticotropin-secreting tumors express galectin-3 (Gal-3), a gene involved in cell growth and apoptosis. (medscape.com)
Surgery1
- Recurrence of the pituitary adenoma after transsphenoidal surgery can be treated with stereotactic Gamma knife radiotherapy. (pediagenosis.com)
Papillary2
- This study contained 152 cases, including 48 follicular nodular disease (FND), 29 follicular adenoma (FA), 57 papillary thyroid carcinoma (PTC), 12 follicular thyroid carcinoma (FTC), 3 medullary thyroid carcinoma (MTC), 2 poorly differentiated thyroid carcinoma (PDTC) and 1 undifferentiated thyroid carcinoma (UDTC). (ijpmonline.org)
- TROP-2 can be considered a useful marker for distinguishing PTC fv cases from follicular nodular disease and follicular adenoma cases because of its high sensitivity in the identification of papillary carcinomas of the thyroid. (ijpmonline.org)
Pituitary adenomas1
- PMID 15871511 -- "Stereotactic radiosurgery for pituitary adenomas: an intermediate review of its safety, efficacy, and role in the neurosurgical treatment armamentarium. (wikibooks.org)
Renal1
- Chromophobe renal cell carcinoma with retrograde venous invasion and gain of chromosome 21: potential harbingers of aggressive clinical behavior. (henryford.com)
Carcinoma2
- Conventional) Clear cell carcinoma showing typical low-grade areas with nests, acini and cords of clear cells intermixed with a delicate network of capillary vessels (a HE, 100x).Chromophobe carcinoma typically shows sheets of cells separated by incomplete septations. (fasttrackmerealestate.com)
- Thyroid findings include adenomas, goiters and the most important to surveil for, follicular carcinoma. (nextstepsinderm.com)
Hepatocellular1
- hepatocellular adenoma a large, fleshy, hypervascular tumor of the liver occurring chiefly in women of childbearing age and associated with oral contraceptive use. (thefreedictionary.com)
Hemorrhage2
- It defines a clinical syndrome and not simply the occurrence of hemorrhage into an adenoma, which is a common and frequently subclinical process. (medlink.com)
- Some cases present with coagulation necrosis of a pituitary adenoma without massive hemorrhage. (medlink.com)
Type2
- many null-cell adenomas are of this type. (thefreedictionary.com)
- The most common histologic type of RCC in BHD is the chromophobe, followed by oncocytomas and mixed variants. (nextstepsinderm.com)
Cells1
- some contain hormone-secreting cells ( endocrine-active adenomas ) but some are not secretory ( endocrine-inactive adenomas ) . (thefreedictionary.com)
Acidophil3
- Adenoma, Acidophil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
- A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (ouhsc.edu)
- Below are the most recent publications written about "Adenoma, Acidophil" by people in Profiles. (ouhsc.edu)
Neoplasms1
- such as papillary, clear cell RCC, nephrogenic adenoma, and urothelial neoplasms 1 sept Hirsch). (aserfavite.es)
Papillary1
- A -mm papillary adenoma fig. And whether conventional randomized studies are justied for some this may contribute to its ultimate state and future offending, mitoses can occur at rest or straining. (tetratherapeutics.com)
Pituitary gland1
- G-protein abnormalities, ras gene mutations, p53 gene deletions, mutations, and rearrangements, and the association of pituitary tumors with the syndrome of multiple endocrine neoplasia have been described and are involved in the development of adenomas in the pituitary gland. (medscape.com)
Tumors5
- Forty-two patients (81%) had a prolactinoma, with the remaining patients having the following tumors: nonfunctioning pituitary adenoma (6 patients), growth hormone-secreting adenoma (2 patients), mammosomatotroph cell adenoma (1 patient), and ACTH-secreting adenoma (1 patient). (medscape.com)
- Stomach tumors, rare in F344 rats (10/2960, 0.3%), were found in the dosed male rats: one adenocarcinoma and a sarcoma in a high-dose male and in the low-dose group a squamous cell papilloma, fibrosarcoma, adenoma, and mucinous adenocarcinoma. (nih.gov)
- Villwock et al noted that pituitary tumors constitute 10-15% of all diagnosed intracranial tumors, 90% of which are adenomas. (medscape.com)
- 4] Nonfunctioning adenomas are associated with hypermethylation of p16 prolactinomas, and corticotropin-secreting tumors express galectin-3 (Gal-3), a gene involved in cell growth and apoptosis. (medscape.com)
- Multiple or bilateral renal carcinomas have been reported in association with this syndrome, most commonly hybrid oncocytic tumors with features of chromophobe renal carcinoma (50%), followed by chromophobe renal cancer, clear cell renal carcinoma, and renal oncocytoma. (medscape.com)
Metanephric adenoma1
- A mutation in the PAX8 gene could prevent or disrupt normal development This entity should not be confused with the similar-sounding metanephric adenoma PAX8 has been shown to interact with NK2 homeobox 1. (aserfavite.es)
Prolactin1
- In another patient with a chromophobe adenoma of the hypophysis, it reduced the excessively elevated prolactin levels. (nih.gov)
Craniopharyngioma1
- It can be used as a diagnostic aid in such conditions as panhypopituitarism, pituitary dwarfism, chromophobe adenoma, postsurgical craniopharyngioma, hypophysectomy, pituitary trauma, acromegaly, gigantism and problems of growth and stature. (nih.gov)
Metastatic2
- 13. Metastatic chromophobe renal cell carcinoma to the brain . (nih.gov)
- The results showed very convincing immuno-boostering effects of female sterilization includes % other diseases such as chromophobe rcc metastatic thyroid carcinoma: History of the residuals against the predictor variable with n degrees of freedom, p. (tetratherapeutics.com)
Transsphenoidal Surgery2
- Fahlbusch, R. and Buchfelder, M. (1988) Transsphenoidal Surgery of Parasellar Pituitary Adenomas. (scirp.org)
- Numerous technological adjuncts are used during transsphenoidal surgery for non-functioning pituitary adenomas (NFPAs), including endoscopy, neuronavigation, intraoperative magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) diversion, and dural closure techniques. (cns.org)
Mucinous1
- MR quantitative 3D shape analysis helps to distinguish mucinous cystic neoplasm from serous oligocystic adenoma. (lifexsoft.org)
Oncocytic1
- FSH can be used to distinguish: adenomas of FSH-producing cells, giant cell adenomas, null cell adenomas and oncocytic cells that normally express focally FSH and/or LH as well as any growth of gonadotropic origin. (anacrom.com)
Epithelial1
- 12. Epithelial and organ-related marker expression in pituitary adenomas. (nih.gov)
Descriptor1
- Adenoma, Chromophobe" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
Carcinoma2
- Chromophobe renal cell carci- noma, adenocarcinoma, and verrucous pseudohyperplastic carcinoma: Although the work along. (norfolkspca.com)
- Carcinoma en cuirasse. (thefreelibrary.com)
Serous1
- Serous tubal intraepithelial PAX2: A reliable marker for nephrogenic adenoma 1 feb Pan-cytokeratin and PAX8 were diffusely positive. (aserfavite.es)
Clinical1
- We aimed to review the literature with regard to CSF leakage associated with nonsurgical treatment of pituitary adenomas in order to further understand the clinical and pathological situations in which this entity typically arises. (medscape.com)
Resection4
- We report a 59 year male with a Knosp grade 4, Hardys C giant pituitary adenoma in which two-stage near total surgical resection via an expanded endoscopic transphenoidal approach and subsequent bifrontal craniotomy was achieved. (scirp.org)
- Typically, resection rates of less than 50% have been reported following surgery on giant pituitary adenomas. (scirp.org)
- This case serves to illustrate that even in the presence of significant suprasellar and parasellar extension, radical resection of giant pituitary adenomas can be achieved. (scirp.org)
- Level III: Transsphenoidal microsurgery or endoscopic resection is recommended for symptomatic relief of nonfunctioning pituitary adenoma patients. (cns.org)
Prolactinomas1
- Conclusions Nonsurgical development of CSF rhinorrhea may occur in the setting of pituitary adenomas, especially following favorable response of invasive prolactinomas to initiation of dopamine agonist therapy. (medscape.com)
Operative2
Marker2
- We suggest that PAX8 is an additional marker for identifying nephrogenic adenoma. (aserfavite.es)
- both may be derived from proliferating renal tubular cells in the urinary tract f renal transcription factor PAX2 as a diagnostic marker for nephrogenic adenoma. (aserfavite.es)
Approach1
- 2008) The Endonasal Microscopic Approach for Pituitary Adenomas and Other Parasellartumors: A 10-Year Experience. (scirp.org)
Surgical1
- 2007) Surgical Treatment of Giant Pituitary Adenomas: Strategies and Results in a Series of 95 Consecutive Patients. (scirp.org)
Patients1
- Results Fifty-two patients with spontaneous or medically induced CSF leaks in the setting of a pituitary adenoma were identified from 29 articles published from 1980 through 2011. (medscape.com)
Treatment2
- [ 22 , 29 ] There have also been several reports of development of CSF rhinorrhea following the initiation of medical treatment for pituitary adenomas. (medscape.com)
- Thus, the incidence of alveolar/bronchiolar adenomas among males is not considered to be related to treatment with C.I. Disperse Yellow 3. (nih.gov)
Shows1
- This graph shows the total number of publications written about "Adenoma, Chromophobe" by people in this website by year, and whether "Adenoma, Chromophobe" was a major or minor topic of these publications. (rush.edu)
Cancer1
- His top areas of expertise are Pancreatic Cancer, Pancreatic Adenoma, Familial Pancreatic Cancer, and Cholangiocarcinoma. (medifind.com)
Giant1
- Sinha, S. and Sharma, B.S. (2010) Giant Pituitary Adenomas-An Enigma Revisited. (scirp.org)
Cases1
- Methods A review of the literature was conducted to identify all cases of nonsurgical CSF leaks associated with pituitary adenomas. (medscape.com)
Analysis1
- Shrestha, R., Bao, G., Wei, W. and Wang, M. (2012) Risk Factor Analysis on the Predictors of the Transsphenoidal Pituitary Surgery on Marco-Adenomas: A Multivariate Logistic Regression Analysis. (scirp.org)
Lower1
- 0.05) lower incidence of hepatocellular adenomas was detected among low-dose (7/50, 1/49, 7/49) male mice. (nih.gov)
Control1
- Pituitary adenomas, with a few exceptions, are not under the control of hypothalamic releasing factors. (medscape.com)