Basophils
Basophil Degranulation Test
Adenoma, Pleomorphic
A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)
Histamine Release
The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.
Adenoma, Villous
Pituitary Neoplasms
Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
Adrenocortical Adenoma
A benign neoplasm of the ADRENAL CORTEX. It is characterized by a well-defined nodular lesion, usually less than 2.5 cm. Most adrenocortical adenomas are nonfunctional. The functional ones are yellow and contain LIPIDS. Depending on the cell type or cortical zone involved, they may produce ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE.
Immunoglobulin E
Adenoma, Chromophobe
Receptors, IgE
Growth Hormone-Secreting Pituitary Adenoma
Colorectal Neoplasms
Antigens, CD63
Colonic Polyps
ACTH-Secreting Pituitary Adenoma
Adenoma, Basophil
Adenoma, Acidophil
A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)
Hypersensitivity
Prolactinoma
Mast Cells
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
Interleukin-3
Antibodies, Anti-Idiotypic
Anaphylaxis
Eosinophils
Adenomatous Polyposis Coli
Allergens
Leukotriene C4
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Histamine
Interleukin-4
Nippostrongylus
Desensitization, Immunologic
Acromegaly
A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)
Cell Degranulation
Cushing Syndrome
A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
Filarioidea
Genes, APC
Anti-Allergic Agents
Hyperparathyroidism
A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
Betula
Skin Tests
Hyperplasia
Immunohistochemistry
Th2 Cells
Neoplasms, Multiple Primary
Urticaria
Hypersensitivity, Immediate
Pituitary ACTH Hypersecretion
Complement C5a
The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION.
Carcinoma
Receptors, CCR3
Hyperaldosteronism
Sphenoid Bone
An irregular unpaired bone situated at the SKULL BASE and wedged between the frontal, temporal, and occipital bones (FRONTAL BONE; TEMPORAL BONE; OCCIPITAL BONE). Sphenoid bone consists of a median body and three pairs of processes resembling a bat with spread wings. The body is hollowed out in its inferior to form two large cavities (SPHENOID SINUS).
N-Formylmethionine Leucyl-Phenylalanine
Interleukin-13
An R201H activating mutation of the GNAS1 (Gsalpha) gene in a corticotroph pituitary adenoma. (1/9)
In the pituitary gland, activating mutations of the GNAS1 (Gsalpha) gene at Gln227 have been identified in adrenocorticotrophin secreting, growth hormone secreting, and prolactin secreting adenomas. To date, mutations at the codon encoding R201, typically underlying the McCune-Albright syndrome and isolated fibrous dysplasia of bone, have been demonstrated only in growth hormone secreting pituitary adenomas. In this study, a polymerase chain reaction amplified target sequence in exon 8 of the GNAS1 gene was sequenced, identifying the first R201 mutation seen in an isolated basophilic adenoma which generated Cushing's disease in a child. This case adds Cushing's disease to the range of human diseases caused by R201 mutations of the GNAS1 gene. (+info)A 2-year dose-response study of lesion sequences during hepatocellular carcinogenesis in the male B6C3F(1) mouse given the drinking water chemical dichloroacetic acid. (2/9)
Dichloroacetic acid (DCA) is carcinogenic to the B6C3F(1) mouse and the F344 rat. Given the carcinogenic potential of DCA in rodent liver and the known concentrations of this compound in drinking water, reliable biologically based models to reduce the uncertainty of risk assessment for human exposure to DCA are needed. Development of such models requires identification and quantification of premalignant hepatic lesions, identification of the doses at which these lesions occur, and determination of the likelihood that these lesions will progress to cancer. In this study we determined the dose response of histopathologic changes occurring in the livers of mice exposed to DCA (0.05-3.5 g/L) for 26-100 weeks. Lesions were classified as foci of cellular alteration smaller than one liver lobule (altered hepatic foci; AHF), foci of cellular alteration larger than one liver lobule (large foci of cellular alteration; LFCA), adenomas (ADs), or carcinomas (CAs). Histopathologic analysis of 598 premalignant lesions revealed that (a)) each lesion class had a predominant phenotype; (b)) AHF, LFCA, and AD demonstrated neoplastic progression with time; and (c)) independent of DCA dose and length of exposure effects, some toxic/adaptive changes in non-involved liver were related to this neoplastic progression. A lesion sequence for carcinogenesis in male B6C3F(1) mouse liver has been proposed that will enable development of a biologically based mathematical model for DCA. Because all classes of premalignant lesions and CAs were found at both lower and higher doses, these data are consistent with the conclusion that nongenotoxic mechanisms, such as negative selection, are relevant to DCA carcinogenesis at lower doses where DCA genotoxicity has not been observed. (+info)Analysis of pituitary hormones and chromogranin A mRNAs in null cell adenomas, oncocytomas, and gonadotroph adenomas by in situ hybridization. (3/9)
To study the relationship between null cell adenomas, oncocytomas and gonadotroph adenomas, we analyzed 32 surgically removed formalin-fixed paraffin-embedded pituitary tumors for the expression of pituitary hormone messenger RNAs (mRNAs) by in situ hybridization (ISH). Most tumors were also analyzed for chromogranin A mRNA. To identify the cell type constituting the tumors and to assess hormone content, all tumors were investigated by histology, transmission electron microscopy and immunohistochemistry. Most null cell adenomas (6/11) and gonadotroph adenomas (9/10) expressed the mRNAs for alpha-subunit of glycoprotein hormones whereas only 2/11 oncocytomas expressed alpha-subunit mRNA. FSH beta and/or LH beta mRNA were present in most null cell and gonadotroph adenomas but only in a few oncocytomas. Prolactin (PRL) mRNA was detected in two null cell tumors and in one gonadotroph adenoma, whereas GH and POMC mRNA were present in one null cell adenoma. Chromogranin A mRNA, which codes for the major secretory granule protein, was present in 25/26 tumors including all tumors that were negative for pituitary hormone mRNAs, indicating adequate preservation of specific mRNA transcripts in the paraffin-embedded sections of tumor cells. These results indicate that null cell adenomas and gonadotroph adenomas are closely related neoplasms and that oncocytomas may represent a functionally defective form of null cell adenoma characterized by mitochondrial abundance, which has retained the capacity to synthesize the major secretory granule protein chromogranin A. Although the cytogenesis of null cell adenomas and oncocytomas is not clear, it can be suggested that these two tumor types are derived from a pluripotential precursor cell that is capable of undergoing multidirectional differentiation and synthesizing various hormones, mainly glycoproteins. (+info)Transcranial management of pituitary tumours with suprasellar extension. (4/9)
A consecutive series of 101 pituitary tumours treated in the 10 year period 1968-78 has been examined, giant lesions being excluded. There were 48 female cases and 53 male, women predominating in the ratio of three to two in the age group 40-50 years and men showing a slight predominance in the age group 50-60 years. Most cases presented with visual deterioration which in 22 cases had been present for between one and two years, and in a further 22 for an even longer period, between two and 10 years. All patients underwent subfrontal craniotomy with mainly radical excision of the tumour followed by radiotherapy. The operative mortality was 0.99%. A system of grading of visual field defect has been described and used to compare preoperatively visual loss with postoperative visual recovery. Fifty-six per cent of cases returned to normal vision over the first two years, and a further 37% showed appreciable improvement in visual fields or acuity or both. Six per cent of cases showed no improvement in visual fields, and one patient died of postoperative deep vein thrombosis and pulmonary embolism. The degree of visual improvement has been correlated with the extent of visual defect, length of visual complaint, and size of the tumour. The importance of central and peripheral visual field analysis is emphasised yet again. (+info)Gonadotroph adenomas of the human pituitary: sex-related fine-structural dichotomy. A histologic, immunocytochemical, and electron-microscopic study of 30 tumors. (5/9)
Thirty pituitary tumors, removed from 14 men and 15 women, were diagnosed as gonadotroph adenomas on the basis of their immunocytochemical and/or ultrastructural features. Serum follicle-stimulating hormone (FSH), but not luteinizing hormone (LH), was elevated in 8 men, whereas none of the women had gonadotropin levels, as measured by radioimmunoassay, inappropriately high for their age. Immunoreactive FSH (sometimes also LH) was present in 13 of 15 tumors in men but only 6 of 13 adenomas in women. By electron microscopy, gonadotroph adenomas in men had uncharacteristic features often similar to those of null-cell adenomas with poorly or moderately developed cytoplasmic organelles. In women, all tumors were well differentiated, with a highly distinctive vesicular dilatation of the Golgi complex ("honeycomb Golgi") as a diagnostic marker present in 14 of 15 adenomas. To the author's knowledge, this is the first example of sex-linked dichotomy within a tumor type expressed as the markedly different ultrastructural appearance of cytoplasmic organelles, especially the Golgi apparatus. (+info)Cytoplasmic filaments of Crooke's hyaline change belong to the cytokeratin class. An immunocytochemical and ultrastructural study. (6/9)
Crooke's hyaline change was studied by immunocytochemistry using an anti-adrenocorticotropic hormone (ACTH) antiserum and five different antisera against cytokeratins. Crooke's hyaline appears in basophil cells of the adenohypophysis in patients with hypercortisolism, presumably as a part of the negative feedback on corticotropin secretion. Previous studies have identified the hyaline material as a simple protein, apparently unrelated to ACTH, and electron microscopy has revealed a loss of secretory granules and an accumulation of 6-9-nm filaments in the cytoplasm of affected cells. In this study, the secretory granules in adenohypophysial cells exhibiting Crooke's hyaline change were labeled by anti-ACTH antibodies, while the hyaline material was positive for cytokeratin with each of the five antisera used. The results suggest that high levels of glucocorticoids may stimulate elaboration of cytokeratins in basophils while they suppress the production and release of ACTH. (+info)Silent corticotropic adenomas of the human pituitary gland: a histologic, immunocytologic, and ultrastructural study. (7/9)
Among 300 surgically removed pituitary adenomas, 17 tumors containing immunoreactive 1-39 adrenocorticotropin (ACTH) and/or 19-39 ACTH, beta-lipotropin, and alpha-endorphin but unassociated with clinical signs of Cushing's disease have been detected. These neoplasms were divided into basophilic adenomas with strong periodic acid-Schiff (PAS) and lead-hematoxylin positivity and chromophobic tumors with moderate or no PAS and lead-hematoxylin positivity. The former were densely granulated tumors with a fine structure strikingly similar to that of functioning corticotropic cell adenomas. The latter were sparsely granulated with varying ultrastructural patterns. The marked morphologic diversity suggests that these adenomas, despite their similar immunocytologic characteristics, represent more than one entity. Clinically, the most common finding was a rapidly progressing visual defect. An unusually high incidence of infarction (5 cases) and recurrence (5 cases) was noted, underlining the importance of correct morphologic diagnosis and careful follow-up. (+info)Immunohistochemical and immunoelectron-microscopic study of pituitary adenomas associated with Cushing's disease. A report of 13 cases. (8/9)
Thirteen pituitary adenomas were removed from patients with Cushing's disease by the transphenoidal route. All cases demonstrated a typical histochemical and ultrastructural pattern. Immunocytochemical study by means of the immunoperoxidase technique and light or electron microscopy demonstrated 1-24/1-39 adrenocorticotropic hormone (ACTH) in all cases, lipotropin/melanotropin (beta-LPH/beta-MSH) in 10 cases, beta-endorphin in 8 cases, and an absence of calcitonin in all cases. In addition, in 2 cases tumor tissue contained a few antiprolactin immunoreactive cells. These ACTH, beta-LPH, and beta-endorphin immunoreactivities may reflect either the peptides themselves or their precursors or intermediate products. The authors also suggest a possible intermediate-lobe-like processing of beta-LPH leading to beta-endorphin production, which may act on PRL cells. In addition, no positive arguments for the existence of a common precursor for calcitonin and ACTH could be provided from this study. (+info)D:Basophil Adenoma - wiki-pain
Diffusion Science radio: Search Results
Corticotropic hormones | definition of corticotropic hormones by Medical dictionary
History of X-rays - Sumers Radiology Blog
Sequence Similarity
- 4FBT: Dpo4 post-insertion complex with the N-(deoxyguanosin-8-yl)-1-aminopyrene lesion Sequence...
Sequence Similarity
- 1N56: Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion Sequence...
Dichloroacetic acid, 3,4-dichlorophenyl ester
Any thoughts on Dichloroacetic acid? | Phoenix Rising ME / CFS Forums
Dichloroacetic acid 3-methylbutyl ester
Harvey Cushing - Wikipedia
Abs. for infertility | DailyStrength
NMR Spectrum
hTERT promoter methylation in pituitary adenomas
EWG Tap Water Database | De Pere Water Department | Dichloroacetic acid
Genevisible - Top 10 cancers for NP 775835
Dichloroacetic acid, 4-tetradecyl ester | C16H30Cl2O2 - PubChem
XOMA Corp (XOMA.OQ) Quote | Reuters
Image: Acidophil Stem Cell Adenoma H&E
basal cell adenoma morphologic abnormality 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
pancreatic alpha d islet cell adenoma drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
familial renal oncocytoma | Semantic Scholar
Null cells legal definition of null cells
THE BODY MIND DICHOTOMY A PROBLEM OR ARTIFACT? 1 - PDF
Cushing's disease
Reprinted in Cushing H (April 1969). "The basophil adenomas of the pituitary body". Ann R Coll Surg Engl. 44 (4): 180-1. PMC ... ISBN 978-0-470-67201-3. Cushing, Harvey (1932). "The basophil adenomas of the pituitary body and their clinical manifestations ... was that the basophil adenoma Minnie might have harbored underwent partial infarction, leading to symptom regression. The other ... Pituitary adenomas are responsible for 80% of endogenous Cushing's syndrome, when excluding Cushing's syndrome from exogenously ...
1932 in science
Reprinted in Cushing, Harvey (April 1969). "The basophil adenomas of the pituitary body". Annals of the Royal College of ... ISBN 978-0-89093-547-7. Cushing, Harvey (1932). "The basophil adenomas of the pituitary body and their clinical manifestations ...
Harvey Cushing
Reprinted in Cushing, Harvey (April 1969). "The basophil adenomas of the pituitary body and their clinical manifestations ( ... ISBN 1560531649 Cushing, Harvey (1932). "The basophil adenomas of the pituitary body and their clinical manifestations ( ... "The Basophil Adenomas of the Pituitary Body and Their Clinical Manifestations: pituitary Basophilism". Cushing was also awarded ...
The Johns Hopkins Medical Journal
First description of what is now known as the Cushing reflex Cushing, Harvey (1932). "The basophil adenomas of the pituitary ...
List of MeSH codes (C04)
... adenoma, acidophil MeSH C04.557.470.035.075 - adenoma, basophil MeSH C04.557.470.035.085 - adenoma, bile duct MeSH C04.557. ... adenoma, acidophil MeSH C04.557.465.625.650.075 - adenoma, basophil MeSH C04.557.465.625.650.095 - adenoma, chromophobe MeSH ... adenoma, acidophil MeSH C04.557.580.625.650.075 - adenoma, basophil MeSH C04.557.580.625.650.095 - adenoma, chromophobe MeSH ... adenoma, liver cell MeSH C04.557.470.035.140 - adenoma, oxyphilic MeSH C04.557.470.035.155 - adenoma, pleomorphic MeSH C04.557. ...
International Classification of Diseases for Oncology
M8300/0 Basophil adenoma (C75.1) Mucoid cell adenoma M8300/3 Basophil carcinoma (C75.1) Basophil adenocarcinoma Mucoid cell ... Black adenoma Pigmented adenoma M8373/0 Adrenal cortical adenoma, clear cell (C74.0) M8374/0 Adrenal cortical adenoma, ... Oxyphilic adenoma Oncocytic adenoma Oncocytoma Hurthle cell adenoma (C73.9) Hurthle cell tumor Follicular adenoma, oxyphilic ... NOS Pick tubular adenoma Sertoli cell adenoma Tubular androblastoma, NOS Testicular adenoma M8640/3 Sertoli cell carcinoma (C62 ...
Ugonjwa wa Cushing, kamusi elezo huru
1932). "The basophil adenomas of the pituitary body and their clinical manifestations (pituitary basophilism).". Bulletin of ... Ezzat S, Asa SL, Couldwell WT, et al. (2004). "The prevalence of pituitary adenomas: a systematic review". Cancer 101 (3): 613- ... adenoma) katika tezi ya pituitari inayotoa viwango vikubwa vya ACTH, ambayo kwa upande wake huongeza kotisoli. Kwa kawaida ...
Index of oncology articles
... basophil - batimastat - BAY 12-9566 - BAY 43-9006 - BAY 56-3722 - BAY 59-8862 - BB-10901 - BBBD - BBR 2778 - BBR 3464 - BCG - ... tubulovillous adenoma - tumor - tumor antigen vaccine - tumor board review - tumor burden - tumor debulking - tumor ... villous adenoma - villus - vinblastine - vinca alkaloid - vincristine - vindesine - vinorelbine - viral vector - virotherapy - ... adenoma - adenopathy - adenosine triphosphate - adenovirus - adjunct agent - adjunctive therapy - adjuvant therapy - ...
Anterior pituitary
A third type of pituitary adenoma secretes excess ACTH, which in turn, causes an excess of cortisol to be secreted and is the ... This is due to the possible confusion with white blood cells, where one may also find basophils and acidophils. Microanatomy of ... This hypersecretion often results in the formation of a pituitary adenoma (tumour), which are benign apart from a tiny fraction ... The chromophils can be further divided into acidophils (alpha cells) and basophils (beta cells). These cells all together ...
Innate lymphoid cell
Basophils and mast cells are also present in these skin lesions, producing IL-4, and PGD2, further activating ILC2s. Psoriasis ... November 2012). "Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth". Nature. 491 ( ...
Marrow Failure Syndromes: Overview, Pathophysiology, Frequency and Mortality/Morbidity
The most common tumors are liver adenomas and hepatomas, primarily in patients who had aplastic anemia that was treated with ... and basophil lineages. The microenvironment, consisting of lymphocytes, macrophages, fibroblasts, endothelial elements, and ...
Pituitary Gland Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Secretory adenomas are typically monoclonal--that is, they secrete a single hormone. Approximately 1 to 2% of adenomas secrete ... Histochemical staining of these granules with pH-dependent dyes allows categorization of the cells into acidophils, basophils, ... GH-secreting adenomas are next most common adenomas, followed by adrenocorticotropic hormone (ACTH)-secreting tumors and ... 21] The vast majority originate in the adenohypophysis and are typically nonsecretory benign adenomas. These adenomas ...
Interpreting the CBC: What's Truly Important?
If you see any basophils, any amount of basophils, that's abnormal. This could indicate a myeloproliferative disorder or ...
Pituitary Gland Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Secretory adenomas are typically monoclonal--that is, they secrete a single hormone. Approximately 1 to 2% of adenomas secrete ... Histochemical staining of these granules with pH-dependent dyes allows categorization of the cells into acidophils, basophils, ... GH-secreting adenomas are next most common adenomas, followed by adrenocorticotropic hormone (ACTH)-secreting tumors and ... 21] The vast majority originate in the adenohypophysis and are typically nonsecretory benign adenomas. These adenomas ...
Endocrine System Anatomy: Overview, Gross Anatomy
Anterior pituitary cells were originally classified as acidophil cells, basophil cells, and chromophore cells. Researchers ... Other causes include non-functioning pituitary adenoma and dopaminergic antagonist drugs (eg, phenothiazines, haloperidol, ...
Code System Concept
Adenocarcinoma in tubulovillous adenoma (morphologic abnormality) {5658009 , SNOMED-CT } Adenocarcinoma in villous adenoma ( ... Mixed acidophil-basophil carcinoma (morphologic abnormality) {23444003 , SNOMED-CT } Mixed cell adenocarcinoma (morphologic ... Basophil carcinoma (morphologic abnormality) {47107000 , SNOMED-CT } Bile duct cystadenocarcinoma (morphologic abnormality) { ...
Marrow Failure Syndromes: Overview, Pathophysiology, Frequency and Mortality/Morbidity
The most common tumors are liver adenomas and hepatomas, primarily in patients who had aplastic anemia that was treated with ... and basophil lineages. The microenvironment, consisting of lymphocytes, macrophages, fibroblasts, endothelial elements, and ...
IMSEAR at SEARO: A clinico-pathologic study of pituitary adenomas.
... lactotroph adenomas). Tumours in group II were chromophobe, acidophil, basophil or mixed adenomas with varying number of ... lactotroph adenomas) and ACTH in all tumours from patients with Cushing's syndrome (corticotroph adenomas). It was observed, ... Thus growth hormone was demonstrated in all tumours from patients with acromegaly (somatotroph adenomas), prolactin in all ... Interestingly, not all the hormones localized by immunohistochemistry in pleurihormonal adenomas were detected in serum and/or ...
Interpreting the CBC: What's Truly Important?
If you see any basophils, any amount of basophils, that's abnormal. This could indicate a myeloproliferative disorder or ...
Code System Concept
Mixed acidophil-basophil adenoma (morphologic abnormality) {48619006 , SNOMED-CT } Mixed cell adenoma (morphologic abnormality ... Basal cell adenoma (morphologic abnormality) {27230006 , SNOMED-CT } Basophil adenoma (morphologic abnormality) {9436005 , ... Acidophil adenoma (morphologic abnormality) {21109002 , SNOMED-CT } Adenoma, no subtype (morphologic abnormality) {32048006 , ... Adrenal cortical adenoma - category (morphologic abnormality) {409703003 , SNOMED-CT } Adrenal cortical adenoma, no ...
Value Set Concept Details
Mixed acidophil-basophil adenoma (morphologic abnormality) Code System Concept Status. Published. Code System Preferred Concept ...
Interpreting the CBC: What's Truly Important?
If you see any basophils, any amount of basophils, that's abnormal. This could indicate a myeloproliferative disorder or ...
Endocrine System Anatomy: Overview, Gross Anatomy
Anterior pituitary cells were originally classified as acidophil cells, basophil cells, and chromophore cells. Researchers ... Other causes include non-functioning pituitary adenoma and dopaminergic antagonist drugs (eg, phenothiazines, haloperidol, ...
Pituitary Gland Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Secretory adenomas are typically monoclonal--that is, they secrete a single hormone. Approximately 1 to 2% of adenomas secrete ... Histochemical staining of these granules with pH-dependent dyes allows categorization of the cells into acidophils, basophils, ... GH-secreting adenomas are next most common adenomas, followed by adrenocorticotropic hormone (ACTH)-secreting tumors and ... 21] The vast majority originate in the adenohypophysis and are typically nonsecretory benign adenomas. These adenomas ...
Pituitary Gland Anatomy: Overview, Gross Anatomy, Microscopic Anatomy
Secretory adenomas are typically monoclonal--that is, they secrete a single hormone. Approximately 1 to 2% of adenomas secrete ... Histochemical staining of these granules with pH-dependent dyes allows categorization of the cells into acidophils, basophils, ... GH-secreting adenomas are next most common adenomas, followed by adrenocorticotropic hormone (ACTH)-secreting tumors and ... 21] The vast majority originate in the adenohypophysis and are typically nonsecretory benign adenomas. These adenomas ...
Endocrine System Anatomy: Overview, Gross Anatomy
Anterior pituitary cells were originally classified as acidophil cells, basophil cells, and chromophore cells. Researchers ... Other causes include non-functioning pituitary adenoma and dopaminergic antagonist drugs (eg, phenothiazines, haloperidol, ...