Adenoma: A benign epithelial tumor with a glandular organization.Adenoma, Acidophil: A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)Acidithiobacillus: A genus of gram-negative rod-shaped bacteria in the class GAMMAPROTEOBACTERIA. They are obligately acidophilic and aerobic, using reduced SULFUR COMPOUNDS to support AUTOTROPHIC GROWTH.Thermoplasmales: An order of aerobic, thermophilic archaea, in the kingdom EURYARCHAEOTA, characterized by the absence of a cell wall. Two genera have been described: THERMOPLASMA and Picrophilus.Microalgae: A non-taxonomic term for unicellular microscopic algae which are found in both freshwater and marine environments. Some authors consider DIATOMS; CYANOBACTERIA; HAPTOPHYTA; and DINOFLAGELLATES as part of microalgae, even though they are not algae.Sulfides: Chemical groups containing the covalent sulfur bonds -S-. The sulfur atom can be bound to inorganic or organic moieties.Thiobacillus: A genus of gram-negative, rod-shaped bacteria that derives energy from the oxidation of one or more reduced sulfur compounds. Many former species have been reclassified to other classes of PROTEOBACTERIA.Adenoma, Pleomorphic: A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)Adenoma, Villous: An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)MiningHydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.Adrenocortical Adenoma: A benign neoplasm of the ADRENAL CORTEX. It is characterized by a well-defined nodular lesion, usually less than 2.5 cm. Most adrenocortical adenomas are nonfunctional. The functional ones are yellow and contain LIPIDS. Depending on the cell type or cortical zone involved, they may produce ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE.Adenoma, Liver Cell: A benign epithelial tumor of the LIVER.RNA, Ribosomal, 16S: Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.Adenoma, Chromophobe: A benign tumor of the anterior pituitary in which the cells do not stain with acidic or basic dyes.Iron: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Growth Hormone-Secreting Pituitary Adenoma: A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH HORMONE leads to ACROMEGALY.Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Colonic Polyps: Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.ACTH-Secreting Pituitary Adenoma: A pituitary adenoma which secretes ADRENOCORTICOTROPIN, leading to CUSHING DISEASE.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Colonoscopy: Endoscopic examination, therapy or surgery of the luminal surface of the colon.Adenomatous Polyps: Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)Prolactinoma: A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA.Adenoma, Basophil: A small tumor of the anterior lobe of the pituitary gland whose cells stain with basic dyes. It may give rise to excessive secretion of ACTH, resulting in CUSHING SYNDROME. (Dorland, 27th ed)Adrenal Cortex Neoplasms: Tumors or cancers of the ADRENAL CORTEX.Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.Acromegaly: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.Genes, APC: Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.Hyperparathyroidism: A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.Salivary Gland Neoplasms: Tumors or cancer of the SALIVARY GLANDS.Colonic Neoplasms: Tumors or cancer of the COLON.Intestinal Neoplasms: Tumors or cancer of the INTESTINES.Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Adrenal Gland Neoplasms: Tumors or cancer of the ADRENAL GLANDS.Pituitary ACTH Hypersecretion: A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.Parotid Neoplasms: Tumors or cancer of the PAROTID GLAND.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Hyperaldosteronism: A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA.Sphenoid Bone: An irregular unpaired bone situated at the SKULL BASE and wedged between the frontal, temporal, and occipital bones (FRONTAL BONE; TEMPORAL BONE; OCCIPITAL BONE). Sphenoid bone consists of a median body and three pairs of processes resembling a bat with spread wings. The body is hollowed out in its inferior to form two large cavities (SPHENOID SINUS).Duodenal Neoplasms: Tumors or cancer of the DUODENUM.Adrenocorticotropic Hormone: An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).Pituitary Gland: A small, unpaired gland situated in the SELLA TURCICA. It is connected to the HYPOTHALAMUS by a short stalk which is called the INFUNDIBULUM.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Hyperparathyroidism, Primary: A condition of abnormally elevated output of PARATHYROID HORMONE due to parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. It is characterized by the combination of HYPERCALCEMIA, phosphaturia, elevated renal 1,25-DIHYDROXYVITAMIN D3 synthesis, and increased BONE RESORPTION.Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.Precancerous Conditions: Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)Sella Turcica: A bony prominence situated on the upper surface of the body of the sphenoid bone. It houses the PITUITARY GLAND.Sigmoidoscopy: Endoscopic examination, therapy or surgery of the sigmoid flexure.Choristoma: A mass of histologically normal tissue present in an abnormal location.Rectal Neoplasms: Tumors or cancer of the RECTUM.Pituitary Apoplexy: The sudden loss of blood supply to the PITUITARY GLAND, leading to tissue NECROSIS and loss of function (PANHYPOPITUITARISM). The most common cause is hemorrhage or INFARCTION of a PITUITARY ADENOMA. It can also result from acute hemorrhage into SELLA TURCICA due to HEAD TRAUMA; INTRACRANIAL HYPERTENSION; or other acute effects of central nervous system hemorrhage. Clinical signs include severe HEADACHE; HYPOTENSION; bilateral visual disturbances; UNCONSCIOUSNESS; and COMA.Human Growth Hormone: A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.Colon: The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.Pituitary Hormones: Hormones secreted by the PITUITARY GLAND including those from the anterior lobe (adenohypophysis), the posterior lobe (neurohypophysis), and the ill-defined intermediate lobe. Structurally, they include small peptides, proteins, and glycoproteins. They are under the regulation of neural signals (NEUROTRANSMITTERS) or neuroendocrine signals (HYPOTHALAMIC HORMONES) from the hypothalamus as well as feedback from their targets such as ADRENAL CORTEX HORMONES; ANDROGENS; ESTROGENS.Adenomatous Polyposis Coli Protein: A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.Parathyroidectomy: Excision of one or more of the parathyroid glands.Urethane: Antineoplastic agent that is also used as a veterinary anesthetic. It has also been used as an intermediate in organic synthesis. Urethane is suspected to be a carcinogen.Intestinal Mucosa: Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.Adenoma, Bile Duct: A benign tumor of the intrahepatic bile ducts.Prolactin: A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.Colon, Descending: The segment of LARGE INTESTINE between TRANSVERSE COLON and the SIGMOID COLON.
A 2-year dose-response study of lesion sequences during hepatocellular carcinogenesis in the male B6C3F(1) mouse given the drinking water chemical dichloroacetic acid. (1/18)
Dichloroacetic acid (DCA) is carcinogenic to the B6C3F(1) mouse and the F344 rat. Given the carcinogenic potential of DCA in rodent liver and the known concentrations of this compound in drinking water, reliable biologically based models to reduce the uncertainty of risk assessment for human exposure to DCA are needed. Development of such models requires identification and quantification of premalignant hepatic lesions, identification of the doses at which these lesions occur, and determination of the likelihood that these lesions will progress to cancer. In this study we determined the dose response of histopathologic changes occurring in the livers of mice exposed to DCA (0.05-3.5 g/L) for 26-100 weeks. Lesions were classified as foci of cellular alteration smaller than one liver lobule (altered hepatic foci; AHF), foci of cellular alteration larger than one liver lobule (large foci of cellular alteration; LFCA), adenomas (ADs), or carcinomas (CAs). Histopathologic analysis of 598 premalignant lesions revealed that (a)) each lesion class had a predominant phenotype; (b)) AHF, LFCA, and AD demonstrated neoplastic progression with time; and (c)) independent of DCA dose and length of exposure effects, some toxic/adaptive changes in non-involved liver were related to this neoplastic progression. A lesion sequence for carcinogenesis in male B6C3F(1) mouse liver has been proposed that will enable development of a biologically based mathematical model for DCA. Because all classes of premalignant lesions and CAs were found at both lower and higher doses, these data are consistent with the conclusion that nongenotoxic mechanisms, such as negative selection, are relevant to DCA carcinogenesis at lower doses where DCA genotoxicity has not been observed. (+info)Effect of long-term treatment with somatostatin analogue (SMS 201-995) on pituitary tumor shrinkage in acromegaly--report of two cases. (2/18)
The effect of long-term somatostatin analogue (SMS 201-995) treatment in two acromegalic patients is reported. Continuous tumor shrinkage was observed even after 129 and 139 weeks of treatment with 600 micrograms of SMS 201-995 daily. A huge and firm adenoma underwent shrinkage during treatment with SMS 201-995. No serious side effect appeared during 160 weeks of treatment. SMS 201-995 has a longterm tumor shrinkage effect and improves endocrinopathies. (+info)Ectopic growth hormone-releasing adenoma in the cavernous sinus--case report. (3/18)
A 55-year-old woman presented a rare ectopic pituitary adenoma in the right cavernous sinus manifesting as acromegaly. The tumor was removed via transsphenoidal approach. Intraoperative observation showed the adenoma was located entirely within the right cavernous sinus, and separated from the normal pituitary gland by the medial wall of the cavernous sinus. There was no communication between the tumor and the pituitary. Histological examination showed a growth hormone-releasing adenoma. Including our case, only eight of 86 reported ectopic adenomas have occurred in the cavernous sinus. Such ectopic presentation may be responsible for failed transsphenoidal surgery for endocrinologically active tumors. (+info)Characterization of human pituitary adenomas in cell cultures by light and electron microscopic morphology and immunolabeling. (4/18)
The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens. The 319 viable monolayer cultures were analyzed in detail by light microscopy and immunocytochemistry within two weeks of cultivation. Some cultures were further characterized by scanning, transmission and immunogold electron microscopy. The viability and detailed in vitro morphology of adenoma cells were found to be characteristic for the various types of pituitary tumors. The sparsely granulated growth hormone, the corticotroph and the acidophil stem cell adenomas provided the highest ratio of viable cultures. Occasionally, prolonged maintenance of cells resulted in long-term cultures. Furthermore, a variety of particular distributions of different hormone-containing granules were found in several cases. Both light microscopic and ultrastructural analyses proved that the primary cultures of adenoma cells retain their physiological features during in vitro cultivations. Our in vitro findings correlated with the routine histopathological examination. These results prove that monolayer cultures of pituitary adenoma cells can contribute to the correct diagnosis and are valid model systems for various oncological and neuroendocrinological studies. (+info)Familial pituitary adenoma--report of four cases from two unrelated families. (5/18)
The authors report four cases of familial pituitary adenomas from two unrelated families. No clinical or biochemical evidence of multiple endocrine neoplasia, type I (MEN-I) was demonstrated. Detailed study of the family trees disclosed no other family members affected by MEN-I. Familial occurrence of pituitary adenomas unassociated with MEN-I is rare. (+info)Pituitary acidophil macroadenoma in a pygmy goat (Capra hircus hircus). (6/18)
This report describes a pituitary acidophil macroadenoma in a goat. Antemortem clinical findings included hypothermia and rumen stasis. Clinicopathologic findings included refractory hypoglycemia, low total thyroxin and insulin concentrations, elevated bile acid concentration, and hyposthenuria. In addition to the pituitary macroadenoma, bilateral atrophy of the zona reticularis of the adrenal glands was observed histologically. (+info)A new look at pituitary adenomas: structure elucidating function. (7/18)
Cases of seven different types of surgically resected pituitary adenoma are described. Included are tumours secreting prolactin or growth hormone or both, and nonfunctioning tumours--undifferentiated and oncocytic tumours, and one tumour with cells of the adrenocorticotropin-melanocyte-stimulating hormone type. The final interpretation of a case of pituitary adenoma should include an assessment of thorough morphologic studies, using not only routine staining and light microscopy but also immunostaining and electron microscopy, to complement the biochemical, radiologic and clinical evaluation. (+info)Transcranial management of pituitary tumours with suprasellar extension. (8/18)
A consecutive series of 101 pituitary tumours treated in the 10 year period 1968-78 has been examined, giant lesions being excluded. There were 48 female cases and 53 male, women predominating in the ratio of three to two in the age group 40-50 years and men showing a slight predominance in the age group 50-60 years. Most cases presented with visual deterioration which in 22 cases had been present for between one and two years, and in a further 22 for an even longer period, between two and 10 years. All patients underwent subfrontal craniotomy with mainly radical excision of the tumour followed by radiotherapy. The operative mortality was 0.99%. A system of grading of visual field defect has been described and used to compare preoperatively visual loss with postoperative visual recovery. Fifty-six per cent of cases returned to normal vision over the first two years, and a further 37% showed appreciable improvement in visual fields or acuity or both. Six per cent of cases showed no improvement in visual fields, and one patient died of postoperative deep vein thrombosis and pulmonary embolism. The degree of visual improvement has been correlated with the extent of visual defect, length of visual complaint, and size of the tumour. The importance of central and peripheral visual field analysis is emphasised yet again. (+info)... adenoma, acidophil MeSH C04.557.470.035.075 --- adenoma, basophil MeSH C04.557.470.035.085 --- adenoma, bile duct MeSH C04.557. ... adenoma, acidophil MeSH C04.557.465.625.650.075 --- adenoma, basophil MeSH C04.557.465.625.650.095 --- adenoma, chromophobe ... adenoma, acidophil MeSH C04.557.580.625.650.075 --- adenoma, basophil MeSH C04.557.580.625.650.095 --- adenoma, chromophobe ... adenoma, liver cell MeSH C04.557.470.035.140 --- adenoma, oxyphilic MeSH C04.557.470.035.155 --- adenoma, pleomorphic MeSH ...
M8280/0 Acidophil adenoma (C75.1) Eosinophil adenoma M8280/3 Acidophil carcinoma (C75.1) Acidophil adenocarcinoma Eosinophil ... Black adenoma Pigmented adenoma M8373/0 Adrenal cortical adenoma, clear cell (C74.0) M8374/0 Adrenal cortical adenoma, ... Oxyphilic adenoma Oncocytic adenoma Oncocytoma Hurthle cell adenoma(C73.9) Hurthle cell tumor Follicular adenoma, oxyphilic ... NOS Pick tubular adenoma Sertoli cell adenoma Tubular androblastoma, NOS Testicular adenoma M8640/3 Sertoli cell carcinoma (C62 ...
A lactotropic cell (also known as prolactin cell, epsilon acidophil, lactotrope, lactotroph, mammatroph, mammotroph) is a cell ... a prolactin-secreting pituitary adenoma. Hypothalamic-pituitary-prolactin axis "Lactotroph" at Dorland's Medical Dictionary. ...
Reprinted in Cushing H (April 1969). "The basophil adenomas of the pituitary body". Ann R Coll Surg Engl. 44 (4): 180-1. PMC ... Given this conviction, and his knowledge of the three anterior pituitary cell types, Cushing hypothesized that if acidophil ... Pituitary adenomas are responsible for 80% of endogenous Cushing's syndrome, when excluding Cushing's syndrome from exogenously ... The first-line treatment of Cushing's disease is surgical resection of ACTH-secreting pituitary adenoma; this surgery involves ...
A lactotropic cell (also known as prolactin cell, epsilon acidophil, lactotrope, lactotroph, mammatroph, mammotroph) is a cell ... a prolactin-secreting pituitary adenoma. ...
A third type of pituitary adenoma secretes excess ACTH, which in turn, causes an excess of cortisol to be secreted and is the ... Nota bene: The term "Basophil" and "Acidophil" is used by some books, whereas others prefer to not use these terms. This is due ... This hypersecretion often results in the formation of a pituitary adenoma (tumour), which are benign apart from a tiny fraction ... Tropic hormones Pituitary adenoma Triple bolus test Posterior pituitary Hypopituitarism Hypothalamic-pituitary-somatic axis ...
Pituitary adenomas are responsible for 80% of endogenous Cushing's syndrome,[3] when excluding Cushing's syndrome from ... Given this conviction, and his knowledge of the three anterior pituitary cell types, Cushing hypothesized that if acidophil ... The first-line treatment of Cushing's disease is surgical resection of ACTH-secreting pituitary adenoma; this surgery involves ... Ding D, Starke RM, Sheehan JP (May 2014). "Treatment paradigms for pituitary adenomas: defining the roles of radiosurgery and ...
March 2002). "Characterization of serotonin(4) receptors in adrenocortical aldosterone-producing adenomas: in vivo and in vitro ... "G-protein-coupled receptors in aldosterone-producing adenomas: a potential cause of hyperaldosteronism". J. Endocrinol. 195 (1 ... Acidophil cell *Somatotropic cell. *Prolactin cell. *Somatomammotrophic cell. *Basophil cell *Corticotropic cell ...
The most common neoplasm affecting the thyroid gland is a benign adenoma, usually presenting as a painless mass in the neck.[64 ... and thyroid adenomas. Malignant nodules, which only occur in about 5% of nodules, include follicular, papillary, medullary ... or from pituitary adenomas which may cause an overproduction of thyroid stimulating hormone.[45] Hyperthyroidism often causes a ... a solitary thyroid adenoma, or inflammation. Other causes include drug-induced excess of iodine, particularly from amiodarone, ...
Pituitary adenomas, noncancerous tumors that occur in the pituitary gland.. All of the functions of the pituitary gland can be ... Acidophil cell *Somatotropic cell. *Prolactin cell. *Somatomammotrophic cell. *Basophil cell *Corticotropic cell ...
... s are tumors that occur in the pituitary gland. Pituitary adenomas are generally divided into three categories dependent upon their biological functioning: benign adenoma, invasive adenoma, and carcinomas. Most adenomas are benign, approximately 35% are invasive and just 0.1% to 0.2 are carcinomas. Pituitary adenomas represent from 10% to 25% of all intracranial neoplasms and the estimated prevalence rate in the general population is approximately 17%. Non-invasive and non-secreting pituitary adenomas are considered to be benign in the literal as well as the clinical sense; however a recent meta-analysis (Fernández-Balsells, et al. 2011) of available research has shown there are to date scant studies - of poor quality - to either support or refute this assumption. Adenomas which exceed 10 millimetres (0.39 in) in size are defined as macroadenomas, with those smaller than ...
A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism; there are very few reports of parathyroid adenomas that were not associated with hyperparathyroidism. A human being usually has four parathyroid glands located on the back surface of the thyroid in the neck. The parathyroids secrete parathyroid hormone (PTH), which increases the concentration of calcium in the blood by inducing the bones to release calcium into the blood and the kidneys to reabsorb it from the urine into the blood. When a parathyroid adenoma causes hyperparathyroidism, more parathyroid hormone is secreted, causing the calcium concentration of the blood to rise, resulting in hypercalcemia. The first signs of a parathyroid adenoma and the resulting primary hyperparathyroidism can include bone fractures and urinary calculi such as kidney stones. Oftentimes parathyroid adenoma is not diagnosed until found ...
... is a type of benign salivary gland tumor that occurs most often in minor salivary glands. In addition to pleomorphic adenoma, the two are the most common tumors of the upper lip. In 95% of cases, canalicular adenoma occurs on the upper lip. The next most common location is the buccal mucosa (inner cheek). Other sites of the mouth, including the parotid gland, are rare for this disease. Canalicular adenoma is most likely to occur in older adults around 70 years of age. There is a predilection for gender with most cases being in females. Canalicular adenoma is characterized as a slow growing, painless swelling, whose diameter can be up to 2 cm. It can be normal or bluish in color. The appearance of this tumor microscopically is very distinct. There are cords of columnar or cuboidal epithelium, which have basophillic nuclei. Parallel rows of cords appear to form long canals. Frequently, there are large cystic spaces. There are no stromal ...
Hepatic adenoma is usually detected by imaging, typically an ultrasound or CT, as a hyperenhancing liver nodule. Given that several liver tumors appear similarly on these imaging modalities, a multi-phase contrast-enhanced imaging study such as CT or MRI may be used to provide more information.[3][4] The significance of making a specific diagnosis is that, unlike other benign liver tumors such as hemangioma and focal nodular hyperplasia, hepatic adenomas have a small but meaningful risk of progressing into a malignancy.[3] Although imaging provides supportive information, a definitive diagnosis of hepatic adenoma requires biopsy of the tissue. ...
... (NIFTP) is an indolent thyroid tumor that was previously classified as an encapsulated follicular variant of papillary thyroid carcinoma, necessitating a new classification as it was recognized that encapsulated tumors without invasion have an indolent behavior, and may be over-treated if classified as a type of cancer. Definition of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP): A noninvasive neoplasm that arises from the thyroid follicular cells (cells that normally make thyroid hormone), showing a predominantly follicular growth pattern and with nuclear features of papillary thyroid carcinoma. There are several specific inclusion and exclusion criteria (see below). When these are met, this tumor has an extremely low malignant potential. Abbreviations: NIFTP: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features EFVPTC: Encapsulated follicular variant of ...
... is an increased parathyroid hormone (PTH) levels in the blood. This occurs either from the parathyroid glands inappropriately making too much PTH (primary hyperparathyroidism) or other events triggering increased production by the parathyroid glands (secondary hyperparathyroidism). Most people with primary disease have no symptoms at the time of diagnosis. In those with symptoms the most common is kidney stones with other potential symptoms including weakness, depression, bone pains, confusion, and increased urination. Both types increase the risk of weak bones. Primary hyperparathyroidism in 80% of cases is due to a single benign tumor known as a parathyroid adenoma with most of the rest of the cases due to a multiple benign tumors. Rarely it may be due to parathyroid cancer. Secondary hyperparathyroidism typically occurs due to vitamin D deficiency, chronic kidney disease, or other causes of low blood calcium. Diagnosis of primary disease is by finding a high blood calcium ...
... is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous glandular cells along with myoepithelial components, having a malignant potentiality. It is the most common type of salivary gland tumor and the most common tumor of the parotid gland. It derives its name from the architectural Pleomorphism (variable appearance) seen by light microscopy. It is also known as "Mixed tumor, salivary gland type", which describes its pleomorphic appearance as opposed to its dual origin from epithelial and myoepithelial elements. The tumor is usually solitary and presents as a slow growing, painless, firm single nodular mass. Isolated nodules are generally outgrowths of the main nodule rather than a multinodular presentation. It is usually mobile unless found in the palate and can cause atrophy of the mandibular ramus when located in the parotid gland. When found in the parotid tail, it may present as an eversion of the ear lobe. Though it is ...
A lactotropic cell (also known as prolactin cell, epsilon acidophil, lactotrope, lactotroph, mammatroph, mammotroph) is a cell in the anterior pituitary which produces prolactin in response to hormonal signals including dopamine which is inhibitory and thyrotropin-releasing hormone which is stimulatory. Other regulators include oxytocin, estrogen and progesterone. Prolactin is involved in the maturation of mammary glands and their secretion of milk in association with oxytocin, estrogen, progesterone, glucocorticoids, and others. Prolactin has numerous other effects in both sexes. Prolactin cells are acidophilic by hematoxylin & eosin stains and comprise about 20% of all cells in the anterior pituitary gland. If these cells undergo neoplastic transformation, they will give rise to a prolactinoma, a prolactin-secreting pituitary adenoma. ...
Deleted in Colorectal Carcinoma, also known as DCC, is a protein which in humans is encoded by the DCC gene. DCC has long been implicated in colorectal cancer. While the official, full name of this gene is Deleted in Colorectal Carcinoma, it is almost universally called Deleted in Colorectal Cancer. The protein product of DCC is a single transmembrane receptor also known as DCC, and it has the same interchangeable name. Since it was first discovered in a colorectal cancer study in 1990, DCC has been the focus of a significant amount of research. DCC held a controversial place as a tumour suppressor gene for many years, and is well known as an axon guidance receptor that responds to netrin-1. More recently DCC has been characterized as a dependence receptor, and many hypotheses have been put forward that have revived interest in DCC's candidacy as a tumour suppressor gene, as it may be a ligand-dependent suppressor that is frequently epigenetically silenced. Early studies of colorectal tumours ...
Lebih dari 80 persen kanker usus besar berasal dari terjadinya polip (adenomatous polyps) yang membuat kanker usus besar sangat cocok untuk ditapis. Diagnosis melalui penapisan terjadi 2-3 tahun sebelum diagnosis ditegakkan karena timbulnya gejala-gejala.[3] Penapisan dapat mengurangi kematian akibat kanker usus besar hingga 60%.[17] Tiga jenis penapisan yang sekarang ini sering dilakukan adalah tes darah samar (fecal occult blood), flexible sigmoidoscopy, dan kolonoskopi.[3] Sigmoidoscopy tidak dapat mendeteksi sisi kanan atas dari usus besar, padahal 42% dari malignansi biasanya ditemukan di sini.[18] Kolonoskopi virtual melalui CT scan yang tidak invasif tampaknya bagus sebagai acuan deteksi kanker dan adenoma, tetapi mahal, ada radiasi, dan tidak dapat mengambil pertumbuhan tak normal yang ditemukan seperti halnya kolonoskopi biasa.[3] Yang paling baru saat ini adalah tes pada kotoran BAB dengan M2-PK Test dengan tingkat akurasi di atas 80%. Tes dapat berbentuk tes ELISA ...
Orqanellər (lat. organella, q.yun. organon - alət, orqan) hüceyrə daxilində bir sıra funksiyaları yetirən quruluşlar. Orqanellər adətən lipid membran vasitəsilə bir-birindən və sitoplazmadan ayrılaraq, hüceyrə daxilində fəaliyyət vahidi əmələ gətirirlər. Orqanel termini bu quruluşların hüceyrədəki rolunun orqanların bədəndəki roluna oxşadığına işarə edir, hərfi mənada "orqancıq" mənasına gəlir. Orqanellər hüceyrədə dayaq, hərəki və yığılan, həssas, yaxud reseptor, hücum və mühafizə, həzm, ekskresiya, sekresiya və s. kimi fəaliyyətlər göstərə bilirlər. Orqanellərə əsasən eukariot hüceyrələrdə rastlansa da, prokariot hüceyrələrdə də funksional olaraq xüsusiləşmiş mikrobölmələr olur[1]. ...
In the anterior pituitary, the term "acidophil" is used to describe two different types of cells: somatotrophs, which generate somatotropin (also known as growth hormone; a protein hormone). mammotrophs, which generate prolactin (a protein hormone). When using standard staining techniques, they cannot be distinguished from each other (though they can be distinguished from basophils and chromophobes), and are therefore identified simply as "acidophils". Acidophile (histology) Basophilic Oxyphil cell Histology image:14002loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732 ...
এক্সট্রিমোফাইল আর্কিয়াগুলো চারটি প্রধান শারীরবৃত্তীয় গ্রুপের সদস্য। এগুলো হচ্ছেঃ halophile, (যেগুলো লবণাক্ত পরিবেশে বাস করে)thermophile, (যেগুলো উচ্চ তাপমাত্রায় বাস করে) alkaliphile(এ সমস্ত আরকিয়া ক্ষারীয় পরিবেশে বাস করে) এবং acidophile(এই আর কি এগুলো এসিডিক পরিবেশে বাস করে)[৬] যদি এই গ্রুপগুলোর বৈশিষ্ট্য সুস্পষ্ট নয়, তবুও আর্কিয়ার শ্রেণীবিন্যাসে এরা গুরুত্বপূর্ণ সূচনা বিন্দু। Halobacterium নামক ...
Acidophil Adenoma. A benign Tumor, usually found in the anterior lobe of the Pituitary Gland, whose Cells stain with acid Dyes ... A specific type of acidophil Adenoma may give rise to nonpuerperal Galactorrhea. (Dorland, 27th ed) ...
Acidophil Stem Cell Adenoma H&E. uploaded on: Sep 13, 2008. by: gliageek. ...
Growth hormone-producing adenoma definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and ... Also called acidophil adenoma, eosinophil adenoma.. The American Heritage® Stedmans Medical Dictionary. Copyright © 2002, 2001 ... growth hormone-producing adenoma in Medicine Expand. growth hormone-producing adenoma n. A tumor that may secrete both growth ...
Acidophil stem cell pituitary adenoma: a case report and literature review.. We present the case of 33-year-old woman with a ... which behaves more aggressively and has a lower surgical cure rate compared to the pure GH-secreting adenoma. The patient had ... an extremely rare subtype of mixed growth hormone/prolactin adenoma, ... developed clinical symptoms and biochemistry consistent with the diagnosis of acromegaly due to acidophilic stem cell adenoma, ...
What is Adenoma of the adrenal gland? Meaning of Adenoma of the adrenal gland medical term. What does Adenoma of the adrenal ... Looking for online definition of Adenoma of the adrenal gland in the Medical Dictionary? Adenoma of the adrenal gland ... Called also pituitary tumor (acidophil), adrenal gland tumor, apocrine tumor, ceruminous gland tumor, eccrine tumor. ... nonsecreting adenoma (nonsecretory adenoma) endocrine-inactive adenoma.. null-cell adenoma a pituitary adenoma whose cells give ...
... nipple adenoma explanation free. What is nipple adenoma? Meaning of nipple adenoma medical term. What does nipple adenoma mean? ... Looking for online definition of nipple adenoma in the Medical Dictionary? ... Called also pituitary tumor (acidophil), adrenal gland tumor, apocrine tumor, ceruminous gland tumor, eccrine tumor. ... nonsecreting adenoma (nonsecretory adenoma) endocrine-inactive adenoma.. null-cell adenoma a pituitary adenoma whose cells give ...
Surgical options include "tranfenoidal adenectomy or hypophysectomy of the acidophil adenoma. Drugs used to reduce growth ... somatotropic cell adenoma of the pituitary somatotropic cell adenoma of mixed cell somatotropic cell adenoma of stem cell ... External radiotherapy is an option in treating acidophil adenomas (www.thedoctorslounge.net/clinlounge/diseases/endocrinology/ ... It can be "caused by eosinophilia or chromophobe adenoma and its usual course is insidious (www.medfamily.org/diagnosis/P/ ...
... pleomorphic adenoma (16), adenolymphomas (15), basal cell adenomas (2), multiple nodular acidophil adenoma (1), myoepithelioma ... pleomorphic adenoma (23), Warthin tumour (5), monomorphic adenoma (2), neurofibroma (1), cyst (1), basal cell adenoma (1) ... In a small sample study of 20 patients with only pleomorphic adenomas included in the benign group, 50% (6/12) of the adenomas ... including oncocytic adenomas, lipomas, lipomatosis, basal cell adenoma, non-sebaceous lymphadenoma, branchiogenic cyst, and ...
Acidophil stem cell adenoma. - Crooke cell adenoma. - Lactotroph adenoma when occurring in men. ... Certain subtypes of pituitary adenoma have been shown to be more clinically aggressive in that they tend to be more invasive, ... Which subtypes of pituitary adenoma must you be aware of as tending to be more clinically agressive? ... The following adenoma subtypes are recognized as having a more aggressive clinical behavior:. ...
Acidophil stem cell adenoma of the human pituitary: Atlas of tumor pathology. Arch Pathol Lab Med,pp. Artigo anterior Artigo ... J Clin Craneofarihgioma ; Pituitary adenomas with invasion of the cavernous sinus space: Introduction In agreement to the new ... New diagnostic strategy for atypical pituitary adenomas: Pediatr Neursurg, 26pp.. Odontogenic calcificant cystic tumor: A ...
This malignancy, but not appropriate except for allergic asthma include a high in the acidophil cells of cimetidine. Urinary ... Steroids modify every three classes, phosphate and a single functional ade- noma. Following recep- tor family has been ...
8280/0 Acidophil adenoma. Synonyms. Eosinophil adenoma. *About ICD-O **. *Using ICD-O-3 online ...
... adenoma, acidophil MeSH C04.557.470.035.075 --- adenoma, basophil MeSH C04.557.470.035.085 --- adenoma, bile duct MeSH C04.557. ... adenoma, acidophil MeSH C04.557.465.625.650.075 --- adenoma, basophil MeSH C04.557.465.625.650.095 --- adenoma, chromophobe ... adenoma, acidophil MeSH C04.557.580.625.650.075 --- adenoma, basophil MeSH C04.557.580.625.650.095 --- adenoma, chromophobe ... adenoma, liver cell MeSH C04.557.470.035.140 --- adenoma, oxyphilic MeSH C04.557.470.035.155 --- adenoma, pleomorphic MeSH ...
M8280/0 Acidophil adenoma (C75.1) Eosinophil adenoma M8280/3 Acidophil carcinoma (C75.1) Acidophil adenocarcinoma Eosinophil ... Black adenoma Pigmented adenoma M8373/0 Adrenal cortical adenoma, clear cell (C74.0) M8374/0 Adrenal cortical adenoma, ... Oxyphilic adenoma Oncocytic adenoma Oncocytoma Hurthle cell adenoma(C73.9) Hurthle cell tumor Follicular adenoma, oxyphilic ... NOS Pick tubular adenoma Sertoli cell adenoma Tubular androblastoma, NOS Testicular adenoma M8640/3 Sertoli cell carcinoma (C62 ...
acidophil adenoma 10.0. IGF1 SST 29. pituitary infarct 10.0. IGF1 SST 30. paraganglioma 10.0. ... is related to pituitary adenoma 1, multiple types and pituitary adenoma. An important gene associated with Hormone Producing ...
Central Nervous System Organ Benign Neoplasm is related to central nervous system germinoma and acidophil adenoma. An important ...
Acidophil adenoma (morphologic abnormality). Code System Preferred Concept Name. Acidophil adenoma (morphologic abnormality). ...
Adenoma, Acidophil. 8. + + +. 18. Hypothyroidism. 8. + + +. 19. Empty Sella Syndrome. 7. + + +. 20. Galactorrhea. 7. + + +. ...
Acidophil adenoma. Acidophil adenoma [M8280/0]. ICD-9-CM, Volume 1&2. Morphology of Neoplasms ICD-9-CM. Details. ... Acinar cell adenoma. Acinar cell adenoma [M8550/0]. ICD-9-CM, Volume 1&2. Morphology of Neoplasms ICD-9-CM. Details. ... Acidophil carcinoma. Acidophil carcinoma [M8280/3]. ICD-9-CM, Volume 1&2. Morphology of Neoplasms ICD-9-CM. Details. ...
Growth Hormone-Secreting Pituitary Adenoma: A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH ... and SA or mammosomatotroph adenoma (MSA) in 46 [22.4%], acidophil stem cell adenoma in 6 [2.9%], and other diagnoses in 6 [2.9 ... Adenoma, Somatotroph; Adenomas, Somatotroph; GH Secreting Pituitary Adenoma; GH-Secreting Pituitary Adenomas; Pituitary Adenoma ... prolactin cell adenomas, melanocorticotroph adenomas and thyrotroph adenomas. ". 01/01/2010 - "Double pituitary adenomas are ...
If a thyroid adenoma secretes thyroid hormones, is it classed as TSH-dependent or TSH-independent? ... Acidophils:. - Somatotrophs -> GH (50%). - Mammotrophs -> PRL (20%). Basophils:. - Corticotrophs -> ACTH (20%). - Thyrotrophs ... Pituitary adenoma -> Cushings Disease. - Ectopic ACTH -> Small Cell LC. Bilateral adrenal enlargement ... True or false; if a pituitary adenoma is functional, hormones can be secreted at a subclinical level? ...
Acidophil stem cell pituitary adenoma: a case report and literature review. Rathi, Manjusha (2019-12) ... In this article, we describe a very rare case of pituitary acidophilic stem cell adenoma, accompanied by a literature review. ...
Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ... The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing ... ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, ...
Szabolcs, I., Weber, M., Kovacs, Z., Irsy, G., Góth, M., Halász, T. & Szilágyi, G., dec. 1 1982, In : Acta medica Academiae Scientiarum Hungaricae. 39, 1-2, p. 11-17 7 p.. Research output: Article ...
AcromegalyProlactinomaBasophilPituitary NeoplasmsBenign neoplasmTumorBasophilsSecretionCarcinomaSecretoryStem cellGigantismNull-cell adenomasIslet CellAtypicalChromophobe adenomaEosinophilic adenomaProlactin cellPlurihormonalAdrenalHormoneSecreteStainAdenocarcinomaNonsecretoryMammosomatotrophGeneMutationsAlveolarGalactorrheaHormonesAdenohypophysisInvasiveCyst
- Acidophil tumor- which produce gigantism and acromegaly. (healthncure.net)
- Common causes of acromegaly include pituitary adenoma and acidophil stem cell adenomas. (wikidoc.org)
- Less common causes of acromegaly include GHRH secreting tumors as hypothalamic tumors , small cell lung cancer , adrenal adenoma , and pheochromocytoma . (wikidoc.org)
- A secretory pituitary adenoma is responsible for acromegaly by excess secretion of the growth hormone and the insulin like growth factor-1 (IGF-1). (wikidoc.org)
- Acromegaly is caused by a mutation in the guanine nucleotide stimulatory protein gene which is responsible for pituitary adenomas . (wikidoc.org)
- Acromegaly results from a growth hormone secreting pituitary adenoma which, as described previously, consists of cells that stain either as acidophils, chromophobes or both. (shahzadshams.com)
- see prolactinoma , corticotroph adenoma , gonadotroph adenoma , growth hormone-secreting adenoma , and thyrotroph adenoma . (thefreedictionary.com)
- lactotrope adenoma ( lactotroph adenoma ) prolactinoma . (thefreedictionary.com)
- If these cells undergo neoplastic transformation, they will give rise to a prolactinoma , a prolactin-secreting pituitary adenoma . (wikipedia.org)
- prolactinoma or pituitary adenomas. (lookformedical.com)
- Basophil adenoma-Cushing's disease. (healthncure.net)
- According to the colors after HE staining, the cells could be divided into chromophobe cells , acidophil cells and basophil cells. (thefreedictionary.com)
- The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. (wakehealth.edu)
- Central Nervous System Organ Benign Neoplasm is related to central nervous system germinoma and acidophil adenoma . (malacards.org)
- Usually B-cell lymphomas Pituitary Pituitary Adenoma: benign neoplasm in anterior lobe of the pituitary Present with either mass effects (including on the rest of the pituitary) and excess hormone secretion At any age or sex, but most common in men aged 20 50 Classified on the basis of hormones they secrete by immunocytochemistry. (newyorkrightsfair.com)
- hepatocellular adenoma a large, fleshy, hypervascular tumor of the liver occurring chiefly in women of childbearing age and associated with oral contraceptive use. (thefreedictionary.com)
- Pituitary adenomas with invasion of the cavernous sinus space: Introduction In agreement to the new classification of the World Health Organization WHOthe Odontogenic Calcificant Cystic Tumor constitutes a benign cystic neoplasia that presents an epithelium similar to an Ameloblastoma, with ghosts cells craenofaringioma may display calcifications in it 1. (loosediamonds.pro)
- Acidophil stem cell adenoma of the human pituitary: Atlas of tumor pathology. (loosediamonds.pro)
- E tumor nagy acidophil vagy un. (vitalitas.hu)
- Poor correlation between acidophils, basophils and chromophobes and the hormones secreted Carcinomas are rare. (newyorkrightsfair.com)
- There are 2 different type of chromophils (of the pars anterior), the acidophils & basophils. (proprofs.com)
- Acidophils are comprised of somatotrophs and mammotrophs whereas basophils are comprised of gonadotrophs, thryotrophs and corticotrophs (Fletcher). (surgpath4u.com)
- Many of the chromophobes may have been acidophils and basophils that have degranulated and have released their hormones. (statpearls.com)
- There is evidence that hypothalamic hormones can regulate hormone secretion by pituitary adenomas. (semanticscholar.org)
- These mutations result in constitutive activation of adenylyl cyclase, which may play a role in both cell division in and excessive GH secretion by these adenomas. (internalmedicine.blog)
- M-8201/3 Cribriform carcinoma, NOS M-8202/0 Microcystic adenoma (C25. (wolfbane.com)
- some contain hormone-secreting cells ( endocrine-active adenomas ) but some are not secretory ( endocrine-inactive adenomas ) . (thefreedictionary.com)
- Pituitary adenomas are divided into secretory and nonsecretory adenomas. (surgpath4u.com)
- Functioning (secretory) adenomas are less likely to cause compressive symptoms, but produce hormones and lead to endocrine symptoms. (surgpath4u.com)
- Secretory adenomas can be further subclassified into the hormone that it produces. (surgpath4u.com)
- Acidophil stem cell pituitary adenoma: a case report and literature review. (knowledgearc.net)
- In this article, we describe a very rare case of pituitary acidophilic stem cell adenoma, accompanied by a literature review. (knowledgearc.net)
- Mammosomatotroph adenoma of the pituitary associated with gigantism and hyperprolactinemia. (semanticscholar.org)
- many null-cell adenomas are of this type. (thefreedictionary.com)
- FSH can be used to distinguish: adenomas of FSH-producing cells, giant cell adenomas, null cell adenomas and oncocytic cells that normally express focally FSH and/or LH as well as any growth of gonadotropic origin. (anacrom.com)
- Adenoma, Islet Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
- This graph shows the total number of publications written about "Adenoma, Islet Cell" by people in this website by year, and whether "Adenoma, Islet Cell" was a major or minor topic of these publications. (rush.edu)
- Below are the most recent publications written about "Adenoma, Islet Cell" by people in Profiles. (rush.edu)
- M-8146/0 Monomorphic adenoma M-8147/0 Basal cell adenoma M-8147/3 Basal cell adenocarcinoma M-8148/2 Glandular intraepithelial neoplasia, grade III M-8149/0 Canalicular adenoma M-8150/0 Islet cell adenoma (C25. (wolfbane.com)
- New diagnostic strategy for atypical pituitary adenomas: Pediatr Neursurg, 26pp. (loosediamonds.pro)
- M8140/0) Adenoma, NOS M8140/1 Atypical adenoma Bronchial adenoma, NOS (C34. (wikipedia.org)
- M-814:M-838) Adenomas and adenocarcinomas M-8140/0 Adenoma, NOS M-8140/1 Atypical adenoma M-8140/2 Adenocarcinoma in situ, NOS M-8140/3 Adenocarcinoma, NOS M-8140/6 Adenocarcinoma, metastatic, NOS M-8141/3 Scirrhous adenocarcinoma M-8142/3 Linitis plastica (C16. (wolfbane.com)
- Pituitary failure due to cyst, post partum pituitary necrosis (Sheehan's syndrome), chromophobe adenoma, Simmond's disease etc. (healthncure.net)
- eosinophilic adenoma growth hormone-secreting adenoma . (thefreedictionary.com)
- Histology of the pituitary lesion showed a typical eosinophilic adenoma which only secreted GH when tested with specific immunostain. (nel.edu)
- A lactotropic cell (also known as prolactin cell, epsilon acidophil, lactotrope, lactotroph, mammatroph, mammotroph) is a cell in the anterior pituitary which produces prolactin in response to hormonal signals including dopamine which is inhibitory and thyrotropin-releasing hormone which is stimulatory. (wikipedia.org)
- plurihormonal adenoma an endocrine-active adenoma that secretes more than one kind of hormone. (thefreedictionary.com)
- This is most often as a result of a pituitary adenoma (specifically pituitary basophilism) or due to excess production of hypothalamus CRH ( corticotropin releasing hormone ) (tertiary hypercortisolism/hypercorticism) that stimulates the synthesis of cortisol by the adrenal glands. (wikipedia.org)
- ACTH-secreting adenoma ( adrenocorticotrophic hormone-secreting adenoma ) corticotroph adenoma . (thefreedictionary.com)
- Called also ACTH-secreting or adrenocorticotropic hormone-secreting adenoma and corticotropinoma . (thefreedictionary.com)
- Hormone Producing Pituitary Cancer, also known as growth hormone-producing pituitary gland neoplasm , is related to pituitary adenoma 1, multiple types and pituitary adenoma . (malacards.org)
- A pituitary gland adenoma composed of acidophilic cells that produce both growth hormone and prolactin. (semanticscholar.org)
- Mammosomatotroph adenoma cells secrete both growth hormone and prolactin. (semanticscholar.org)
- Pituitary adenomas are positive for neuroendocrine markers (e.g. synaptophysin, neuron-specific enolase (NSE)), low molecular weight keratins as well as markers specific to the hormone being produced (e.g. (surgpath4u.com)
- What does the acidophils secrete? (proprofs.com)
- Acidophils: The cytoplasm of these cells stain red or orange. (statpearls.com)
- M-8210/0 Adenomatous polyp, NOS M-8210/2 Adenocarcinoma in situ in adenomatous polyp M-8210/3 Adenocarcinoma in adenomatous polyp M-8211/0 Tubular adenoma, NOS M-8211/3 Tubular adenocarcinoma M-8212/0 Flat adenoma M-8213/0 Serrated adenoma (C18. (wolfbane.com)
- M-8401/0 Apocrine adenoma M-8401/3 Apocrine adenocarcinoma M-8402/0 Nodular hidradenoma (C44. (wolfbane.com)
- nonsecreting adenoma ( nonsecretory adenoma ) endocrine-inactive adenoma . (thefreedictionary.com)
- Small nonsecretory adenomas can slowly enlarge and cause local compression symptoms (i.e. visual defects) or compromise normal pituitary gland function (i.e. hypopituitarism). (surgpath4u.com)
- The pathophysiology of mammosomatotroph adenomas remains unclear. (semanticscholar.org)
- Non-functioning pituitary adenomas infrequently harbor G-protein gene mutations. (cdc.gov)
- GNASI mutations are seen in 40% of GH-secreting adenomas. (surgpath4u.com)
- To search for mutations of GNAS1 and GNAI2 in a continuous series of non-functioning pituitary adenoma (NFPA) patients neurosurgically treated. (cdc.gov)
- M-8251/0 Alveolar adenoma (C34. (wolfbane.com)
- A specific type of acidophil Adenoma may give rise to nonpuerperal Galactorrhea . (online-medical-dictionary.org)
- The role of hypothalamic hormones in the pathogenesis of pituitary adenomas. (semanticscholar.org)
- This mutation is not seen in adenomas making other hormones since their actions do not depend on a c-AMP pathway (Kumar). (surgpath4u.com)
- Acidophils usually contain polypeptide hormones. (statpearls.com)
- 2. An acidophil of the adenohypophysis. (tabers.com)
- Larger adenomas are more likely to be invasive. (surgpath4u.com)
- A clear progression from pituitary adenomas to invasive adenomas to pituitary carcinomas has not been demonstrated. (surgpath4u.com)
- A nyaki UH szerepe a c lz son, az echoszeg ny ter let biopsi j n, a cyst k vizsg lat n t lmen en, a betegs g k vet s ben is fontos. (vitalitas.hu)