Parathyroid Neoplasms: Tumors or cancer of the PARATHYROID GLANDS.Parathyroid Glands: Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.Hyperparathyroidism: A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.Adenoma: A benign epithelial tumor with a glandular organization.Parathyroid Hormone: A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.Hyperparathyroidism, Primary: A condition of abnormally elevated output of PARATHYROID HORMONE due to parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. It is characterized by the combination of HYPERCALCEMIA, phosphaturia, elevated renal 1,25-DIHYDROXYVITAMIN D3 synthesis, and increased BONE RESORPTION.Parathyroidectomy: Excision of one or more of the parathyroid glands.Hypercalcemia: Abnormally high level of calcium in the blood.Parathyroid Diseases: Pathological processes of the PARATHYROID GLANDS. They usually manifest as hypersecretion or hyposecretion of PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body.Urinary Calculi: Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.Prolactinoma: A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA.Pituitary Gland: A small, unpaired gland situated in the SELLA TURCICA. It is connected to the HYPOTHALAMUS by a short stalk which is called the INFUNDIBULUM.Growth Hormone-Secreting Pituitary Adenoma: A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH HORMONE leads to ACROMEGALY.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)ACTH-Secreting Pituitary Adenoma: A pituitary adenoma which secretes ADRENOCORTICOTROPIN, leading to CUSHING DISEASE.Adenoma, Chromophobe: A benign tumor of the anterior pituitary in which the cells do not stain with acidic or basic dyes.Pituitary Gland, Anterior: The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the ADENOHYPOPHYSEAL HORMONES that regulate vital functions such as GROWTH; METABOLISM; and REPRODUCTION.Acromegaly: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)Electronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Food Dispensers, Automatic: Mechanical food dispensing machines.Editorial Policies: The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.Authorship: The profession of writing. Also the identity of the writer as the creator of a literary production.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Postal Service: The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Legislation, Food: Laws and regulations concerned with industrial processing and marketing of foods.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Job Application: Process of applying for employment. It includes written application for employment or personal appearance.Peer Review: An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.Peer Review, Research: The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.Ampulla of Vater: A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.Manuscripts as Topic: Compositions written by hand, as one written before the invention or adoption of printing. A manuscript may also refer to a handwritten copy of an ancient author. A manuscript may be handwritten or typewritten as distinguished from a printed copy, especially the copy of a writer's work from which printed copies are made. (Webster, 3d ed)Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Equipment Reuse: Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.Thorax: The upper part of the trunk between the NECK and the ABDOMEN. It contains the chief organs of the circulatory and respiratory systems. (From Stedman, 25th ed)Parental Consent: Informed consent given by a parent on behalf of a minor or otherwise incompetent child.Intellectual Property: Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)Access to Information: Individual's rights to obtain and use information collected or generated by others.Minors: A person who has not attained the age at which full civil rights are accorded.Urology: A surgical specialty concerned with the study, diagnosis, and treatment of diseases of the urinary tract in both sexes, and the genital tract in the male. Common urological problems include urinary obstruction, URINARY INCONTINENCE, infections, and UROGENITAL NEOPLASMS.Cystadenoma: A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. In some instances, considerable portions of the neoplasm, or even the entire mass, may be cystic. (Stedman, 25th ed)Prostatism: Lower urinary tract symptom, such as slow urinary stream, associated with PROSTATIC HYPERPLASIA in older men.Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.Reference Books, Medical: Books in the field of medicine intended primarily for consultation.Lower Urinary Tract Symptoms: Symptoms of disorders of the lower urinary tract including frequency, NOCTURIA; urgency, incomplete voiding, and URINARY INCONTINENCE. They are often associated with OVERACTIVE BLADDER; URINARY INCOMPETENCE; and INTERSTITIAL CYSTITIS. Lower urinary tract symptoms in males were traditionally called PROSTATISM.Urination Disorders: Abnormalities in the process of URINE voiding, including bladder control, frequency of URINATION, as well as the volume and composition of URINE.5-alpha Reductase Inhibitors: Drugs that inhibit 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE. They are commonly used to reduce the production of DIHYDROTESTOSTERONE.Urologic Diseases: Pathological processes of the URINARY TRACT in both males and females.Adenoma, Liver Cell: A benign epithelial tumor of the LIVER.Ancillary Services, Hospital: Those support services other than room, board, and medical and nursing services that are provided to hospital patients in the course of care. They include such services as laboratory, radiology, pharmacy, and physical therapy services.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.Hawks: Common name for many members of the FALCONIFORMES order, family Accipitridae, generally smaller than EAGLES, and containing short, rounded wings and a long tail.Pierre Robin Syndrome: Congenital malformation characterized by MICROGNATHIA or RETROGNATHIA; GLOSSOPTOSIS and CLEFT PALATE. The mandibular abnormalities often result in difficulties in sucking and swallowing. The syndrome may be isolated or associated with other syndromes (e.g., ANDERSEN SYNDROME; CAMPOMELIC DYSPLASIA). Developmental mis-expression of SOX9 TRANSCRIPTION FACTOR gene on chromosome 17q and its surrounding region is associated with the syndrome.Nodal Signaling Ligands: Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE.VirginiaWilliams Syndrome: A disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, including the ELASTIN gene. Clinical manifestations include SUPRAVALVULAR AORTIC STENOSIS; MENTAL RETARDATION; elfin facies; impaired visuospatial constructive abilities; and transient HYPERCALCEMIA in infancy. The condition affects both sexes, with onset at birth or in early infancy.Vanilla: A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).Azores: A group of nine islands and several islets belonging to Portugal in the north Atlantic Ocean off the coast of Portugal. The islands are named after the acores, the Portuguese for goshawks, living there in abundance. (Webster's New Geographical Dictionary, 1988, p102 & Room, Brewer's Dictionary of Names, 1992, p42)Pinnipedia: The suborder of aquatic CARNIVORA comprising the WALRUSES; FUR SEALS; SEA LIONS; and EARLESS SEALS. They have fusiform bodies with very short tails and are found on all sea coasts. The offspring are born on land.History, 20th Century: Time period from 1901 through 2000 of the common era.BooksAppointments and Schedules: The different methods of scheduling patient visits, appointment systems, individual or group appointments, waiting times, waiting lists for hospitals, walk-in clinics, etc.Endocrinology: A subspecialty of internal medicine concerned with the metabolism, physiology, and disorders of the ENDOCRINE SYSTEM.Adenoma, Pleomorphic: A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)Parotid Neoplasms: Tumors or cancer of the PAROTID GLAND.Salivary Gland Neoplasms: Tumors or cancer of the SALIVARY GLANDS.Vagus Nerve Diseases: Diseases of the tenth cranial nerve, including brain stem lesions involving its nuclei (solitary, ambiguus, and dorsal motor), nerve fascicles, and intracranial and extracranial course. Clinical manifestations may include dysphagia, vocal cord weakness, and alterations of parasympathetic tone in the thorax and abdomen.Adenolymphoma: A benign tumor characterized histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid.Submandibular Gland: One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)Salivary Glands: Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).Salivary Glands, Minor: Accessory salivary glands located in the lip, cheek, tongue, floor of mouth, palate and intramaxillary.Palatal Neoplasms: Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA.Liver Neoplasms: Tumors or cancer of the LIVER.Adenoma, Basophil: A small tumor of the anterior lobe of the pituitary gland whose cells stain with basic dyes. It may give rise to excessive secretion of ACTH, resulting in CUSHING SYNDROME. (Dorland, 27th ed)Adenoma, Oxyphilic: A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
(1/4752) Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway.

Overexpression of cell surface glycoproteins of the CD44 family is an early event in the colorectal adenoma-carcinoma sequence. This suggests a link with disruption of APC tumor suppressor protein-mediated regulation of beta-catenin/Tcf-4 signaling, which is crucial in initiating tumorigenesis. To explore this hypothesis, we analyzed CD44 expression in the intestinal mucosa of mice and humans with genetic defects in either APC or Tcf-4, leading to constitutive activation or blockade of the beta-catenin/Tcf-4 pathway, respectively. We show that CD44 expression in the non-neoplastic intestinal mucosa of Apc mutant mice is confined to the crypt epithelium but that CD44 is strongly overexpressed in adenomas as well as in invasive carcinomas. This overexpression includes the standard part of the CD44 (CD44s) as well as variant exons (CD44v). Interestingly, deregulated CD44 expression is already present in aberrant crypt foci with dysplasia (ACFs), the earliest detectable lesions of colorectal neoplasia. Like ACFs of Apc-mutant mice, ACFs of familial adenomatous polyposis (FAP) patients also overexpress CD44. In sharp contrast, Tcf-4 mutant mice show a complete absence of CD44 in the epithelium of the small intestine. This loss of CD44 concurs with loss of stem cell characteristics, shared with adenoma cells. Our results indicate that CD44 expression is part of a genetic program controlled by the beta-catenin/Tcf-4 signaling pathway and suggest a role for CD44 in the generation and turnover of epithelial cells.  (+info)

(2/4752) MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis.

Our studies on interactions of a folate-metabolizing gene polymorphism and dietary intake in colorectal tumorigenesis demonstrate the potential importance of studying interactions between genotype and environmental exposure in relation to cancer risk. We observed an inverse association of a polymorphism (667C --> T, ala --> val) in the methylenetetrahydrofolate reductase (MTHFR) gene with colorectal cancer but not with colorectal adenomas. The inverse association of methionine and adverse association of alcohol with colorectal cancer were stronger among val/val individuals. These interactions were not present in studies of colorectal adenomas. Our studies illustrate that studying gene-environment interactions in relation to cancer can be of importance in clarifying cancer etiology as well as pointing to preventive dietary modifications.  (+info)

(3/4752) Expression of relaxin-like factor is down-regulated in human testicular Leydig cell neoplasia.

In addition to their role in steroidogenesis in the male, testicular Leydig cells constitutively express large amounts of the peptide relaxin-like factor (RLF), also known as Ley-IL. The Leydig cell-derived RLF belongs to the insulin-like superfamily, which also includes relaxin, insulin and the insulin-like growth factors, and within the testis is a specific marker of Leydig cells. Little information is available either on the regulation of gene expression or on the function of this Leydig cell-derived peptide. In the present study we have investigated the expression pattern of human RLF in patients with rare Leydig cell hyperplasia and adenoma. The expression of both mRNA and protein appear to be decreased in hyperplastic Leydig cells, whereas in the Leydig cell adenomas studied, large central areas of the adenoma were devoid of RLF mRNA and protein. Only Leydig cells located at the periphery of the adenoma displayed expression of RLF, with full agreement between in-situ hybridization and immunohistochemistry. It thus appears that the expression of the RLF gene and its products are down-regulated in Leydig cell hyperplasia and adenoma, consistent with a concomitant dedifferentiation of these cells.  (+info)

(4/4752) Effect of retinoids on AOM-induced colon cancer in rats: modulation of cell proliferation, apoptosis and aberrant crypt foci.

We have previously reported that the retinoids, 4-(hydroxyphenyl)retinamide (4-HPR) and 9-cis-retinoic acid (RA) prevented azoxymethane (AOM)-induced colon tumors and along with 2-(carboxyphenyl)retinamide (2-CPR) prevented aberrant crypt foci (ACF). In this study, we evaluated the effect of 2-CPR on AOM-induced colon tumors and the effect of the three retinoids on apoptosis and cell proliferation. Male F344 rats were administrated 15 mg/kg AOM at weeks 7 and 8 of age. 2-CPR (315 mg/kg) was administered in the diet starting either 1 week before or at week 12 after the first dose of AOM. The rats continued to receive the 2-CPR until killed at week 46. Unlike the demonstrated prevention of colon cancer by the other two retinoids, both dosing schedules of 2-CPR resulted in an approximate doubling of the yield of colon tumors. In adenomas, 2-CPR, 4-HPR and 9-cis-RA were equally effective in reducing mitotic activity, while only 4-HPR and 9-cis-RA but not 2-CPR enhanced apoptosis. When administered for only the 6 days prior to killing 4-HPR but not 2-CPR decreased the Mitotic Index and increased the Apoptotic Index in adenomas. In non-involved crypts, chronic exposure to 4-HPR and 9-cis-RA in contrast to 2-CPR reduced the Mitotic Index and enhanced the Apoptotic Index. In concurrence with our previous study, both 2-CPR and 4-HPR were very potent in preventing ACF when administered in the diet starting 1 week before the first dose of AOM and continuing for the 5 weeks of the study. Hence, unlike the other two retinoids, 2-CPR, although very potent in preventing ACF, enhanced rather than prevented AOM-induced colon cancer. Furthermore, our results suggest that the effect of 2-CPR on tumor yield is different from 4-HPR and 9-cis-RA because, unlike them, it does not enhance apoptosis.  (+info)

(5/4752) Reduced lung tumorigenesis in human methylguanine DNA--methyltransferase transgenic mice achieved by expression of transgene within the target cell.

Human methylguanine-DNA methyltransferase (MGMT) transgenic mice expressing high levels of O6-alkylguanine-DNA alkyltransferase (AGT) in lung were crossbred to A/J mice that are susceptible to pulmonary adenoma to study the impact of O6-methylguanine (O6mG)-DNA adduct repair on NNK-induced lung tumorigenesis. Expression of the chimeric human MGMT transgene in lung was identified by northern and western blot analysis, immunohistochemistry assay and enzymatic assay. AGT activity was 17.6 +/- 3.2 versus 1.2 +/- 0.4 fmol/microg DNA in lung of MGMT transgenic mice compared with non-transgenic mice. Immunohistochemical staining with anti-human AGT antibody showed that human AGT was expressed throughout the lung. However, some epithelial cells of bronchi and alveoli did not stain for human AGT, suggesting that the human MGMT transgene expression was heterogeneous. After 100 mg/kg NNK i.p. injection in MGMT transgenic mice, lung AGT activity remained much higher and levels of lung O6mG-DNA adducts in MGMT transgenic mice were lower than those of non-transgenic mice. In the tumorigenesis study, mice received 100 mg/kg NNK at 6 weeks of age and were killed 44 weeks later. Ten of 17 MGMT transgenic mice compared with 16 of 17 non-transgenic mice had lung tumors, P < 0.05. MGMT transgenic mice had lower multiplicity and smaller sized lung tumors than non-transgenic mice. Moreover, a reduction in the frequency of K-ras mutations in lung tumors was found in MGMT transgenic mice (6.7 versus 50% in non-transgenic mice). These results indicate that high levels of AGT expressed in mouse lung reduce lung tissue susceptibility to NNK-induced tumorigenesis due to increased repair capacity for O6mG, subsequently, decreased mutational activation of K-ras oncogene. Heterogeneity in the level of AGT expressed in different lung cell populations or other forms of carcinogenic DNA damage caused by NNK may explain the residual incidence of lung tumors in MGMT transgenic mice.  (+info)

(6/4752) Possible carcinogenic effects of X-rays in a transgenerational study with CBA mice.

A lifetime experiment using 4279 CBA/J mice was carried out to investigate whether the pre-conceptual exposure of sperm cells to X-ray radiation or urethane would result in an increased cancer risk in the untreated progeny, and/or increased susceptibility to cancer following exposure to a promoting agent. The study consisted of four main groups, namely a control group (saline), a urethane group (1 mg/g body wt) and two X-ray radiation groups (1 Gy, 2 Gy). At 1, 3 and 9 weeks after treatment, the males of these four parental groups were mated with untreated virgin females. The offspring of each parental group was divided into two subgroups: one received s.c. urethane (0.1 mg/g body wt once) as a promoter, the other saline, at the age of 6 weeks. All animals were evaluated for the occurrence of tumours. K-ras oncogene and p53 tumour suppressor gene mutations were investigated in frozen lung tumour samples. The female offspring of male parents exposed to X-rays 1 week before their mating showed a trend towards a higher tumour incidence of the haematopoietic system than the F1 controls. In addition, a higher percentage of bronchioloalveolar adenocarcinomas in male offspring born to irradiated paternals mated 1 week after X-ray treatment points to a plausible increased sensitivity of post-meiotic germ cell stages towards transgenerational carcinogenic effects. On the other hand, no increased tumour incidence and malignancy were observed in the offspring born to irradiated paternals mated 3 and 9 weeks after X-ray treatment. Paternal urethane treatment 1, 3 and 9 weeks prior to conception did not result in significantly altered incidence or malignancy of tumours of the lung, liver and haematopoietic tissue in the offspring. K-ras mutations increased during tumour progression from bronchioloalveolar hyperplasia to adenoma. Codon 61 K-ras mutations were more frequent in lung tumours of urethane-promoted progeny from irradiated parents than from control parents. P53 mutations were absent from these lung alterations.  (+info)

(7/4752) Epithelial thyroid tumors in cows.

From 1964 to 1973, 370 tumors were collected from cows of unknown age. Ten (2.7%) of these were primary thyroid tumors. Three were malignant. The benign tumors were solitary encapsulated adenomas in the parenchyma with more or less defined trabeculae, tubular, and microfollicular pattern. One of the malignant tumors was a cystic papillary adenocarcinoma, and two were small cell carcinomas consisting of small, sometimes binuclear, pleomorphic cells.  (+info)

(8/4752) The elevated serum alkaline phosphatase--the chase that led to two endocrinopathies and one possible unifying diagnosis.

A 39-year-old Chinese man with hypertension being evaluated for elevated serum alkaline phosphatase (SAP) levels was found to have an incidental right adrenal mass. The radiological features were characteristic of a large adrenal myelolipoma. This mass was resected and the diagnosis confirmed pathologically. His blood pressure normalised after removal of the myelolipoma, suggesting that the frequently observed association between myelolipomas and hypertension may not be entirely coincidental. Persistent elevation of the SAP levels and the discovery of hypercalcaemia after surgery led to further investigations which confirmed primary hyperparathyroidism due to a parathyroid adenoma. The patient's serum biochemistry normalised after removal of the adenoma. The association of adrenal myelolipoma with primary hyperparathyroidism has been reported in the literature only once previously. Although unconfirmed by genetic studies this association may possibly represent an unusual variation of the multiple endocrine neoplasia type 1 syndrome.  (+info)

*  Parathyroid adenoma
A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism; there are very few ... Oftentimes parathyroid adenoma is not diagnosed until found on standard blood-tests that reveal high calcium content in the ... Parathyroid adenoma can be associated with overexpression of the cyclin D1 gene. Hyperparathyroidism is confirmed by blood ... sometimes parathyroid adenomas can be ablated by ethanol injection, guided by ultrasound. Endocrine system Parathyroid disease ...
*  Pituitary adenoma
... benign adenoma, invasive adenoma, and carcinomas. Most adenomas are benign, approximately 35% are invasive and just 0.1% to 0.2 ... Pituitary adenomas are tumors that occur in the pituitary gland. Pituitary adenomas are generally divided into three categories ... Various types of headaches are common in patients with pituitary adenomas. The adenoma may be the prime causative factor behind ... Pituitary adenomas are classified as endocrine tumors (not brain tumors). Pituitary adenomas are classified based upon ...
*  Hyperparathyroidism
"Parathyroid Adenoma". Archived from the original on 2011-07-16. Carrol, Mary F.; David S. Schade (1 May 2003). "A Practical ... Primary hyperparathyroidism in 80% of cases is due to a single benign tumor known as a parathyroid adenoma with most of the ... Parathyroid adenomas are very rarely detectable on clinical examination. Surgical removal of a parathyroid tumor eliminates the ... There is oversecretion of PTH due to a parathyroid adenoma, parathyroid hyperplasia or, rarely, a parathyroid carcinoma. This ...
*  Adenoma
An adenoma (from Greek αδένας, adeno-, "gland" + -ώμα, -oma, "tumor") (/ˌædɪˈnoʊmə/; plural adenomas or adenomata /ˌædɪˈnoʊmɪtə ... Hepatic adenomas are a rare benign tumour of the liver, which may present with hepatomegaly or other symptoms. Breast adenomas ... Bronchial adenomas are adenomas in the bronchi. They may cause carcinoid syndrome, a type of paraneoplastic syndrome. A ... A physician's response to detecting an adenoma in a patient will vary according to the type and location of the adenoma among ...
*  Nipple adenoma
There are reported cases of cancers arising within nipple adenomas, and following excision of nipple adenomas, but these are ... Nipple adenomas most commonly occur in 30- to 40-year-old women, but can also occur in men. They can also occur at any age, ... Nipple adenomas may be felt as a lump under the nipple or areola. They may come to attention because of nipple pain, ulceration ... A nipple adenoma is a rare benign tumour of the breast. The condition may also be known as : Florid papillomatosis of the ...
*  Nephrogenic adenoma
... , also mesonephric adenoma and nephrogenic metaplasia, is a benign growth typically found in the urinary ... This entity should not be confused with the similar-sounding metanephric adenoma. Nephrogenic adenomas are diagnosed under the ... Metanephric adenoma Low mag. High mag. Mazal, PR.; Schaufler, R.; Altenhuber-Müller, R.; Haitel, A.; Watschinger, B.; Kratzik, ... Peeker R Aldenborg F Fall M: Nephrogenic adenoma: A study with special reference to clinical presentation. BR J UROL 1997;80(4 ...
*  Hepatocellular adenoma
Micrograph of hepatic adenoma. H&E stain Micrograph of hepatic adenoma. Reticulin stain Hepatic adenomas are related to ... Hepatocellular adenoma (also known as hepatic adenoma or hepadenoma) is a rare, benign liver tumor. It most commonly occurs in ... Since hepatic adenomas can be large (8-15 cm), patients may notice a palpable mass. However, hepatic adenomas are usually ... Patients with adenomas should avoid oral contraceptives or hormonal replacement therapy. Pregnancy could cause the adenoma to ...
*  Adenoma sebaceum
... may at times be associated with tuberous sclerosis. Gradually the papules become more prominent with time and ... Adenoma sebaceum is a misnamed cutaneous disorder consisting of angiofibromas that begin in childhood (generally present ... ISBN 0-7216-2921-0. "DermIS - Adenoma Sebaceum (information on the diagnosis)". www.dermis.net. Retrieved 2016-01-01. ...
*  Pleomorphic adenoma
Warthin's tumor - monomorphic adenoma Carcinoma Sialadenitis Cohen EG, Patel SG, Lin O, et al. (Jun 2004). "Fine-needle ... Pleomrphic adenoma at GP Notebook, U.K Harvard CT and MR UK Parotid tumor support forum. ... Though it is classified as a benign tumor, pleomorphic adenomas have the capacity to grow to large proportions and may undergo ... Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous ...
*  Ceruminous adenoma
A ceruminous adenoma (also known as adenoma of the ceruminous gland and ceruminoma) is a benign glandular neoplasm which arises ... Other tumors which need to be excluded include a neuroendocrine adenoma of the middle ear (middle ear adenoma), paraganglioma, ... Ceruminous adenoma Ceruminous pleomorphic adenoma Ceruminous syringocystadenoma papilliferum All of the tumors are ... Ceruminous adenoma are rare tumors, accounting for less than 1% of all external ear tumors. The patients will present with a ...
*  Adrenocortical adenoma
A adrenocortical adenoma (or adrenal cortical adenoma, or sometimes simply adrenal adenoma) is a benign tumor of the adrenal ... Nevertheless, these apparently non-functioning adenomas are most often encountered in elder obese people. There is some debate ... Very occasionally, a true adrenal cortical adenoma is associated with the clinical manifestations of Conn's syndrome, and can ... adrenal tumor "Definition: adrenocortical adenoma from Online Medical Dictionary". ...
*  Thyroid adenoma
A thyroid adenoma is a benign tumor of the thyroid gland. Almost all thyroid adenomas are follicular adenomas. Follicular ... Hyalinizing trabecular adenoma Papillary adenomas are very rare. A thyroid adenoma is distinguished from a multinodular goiter ... A thyroid adenoma may be clinically silent ("cold" or "warm" adenoma), or it may be a functional tumor, producing excessive ... and may be referred to as a toxic thyroid adenoma. Thyroid follicular adenoma ranges in diameter from 3 cm on an average, but ...
*  Sebaceous adenoma
A sebaceous adenoma, a type of adenoma, a cutaneous condition characterized by a slow-growing tumor usually presenting as a ... Sebaceous adenomas, in isolation, are not significant; however, they may be associated with Muir-Torre syndrome, a genetic ... It is also linked to hereditary nonpolyposis colorectal cancer (Lynch Syndrome). It is not the same as "adenoma sebaceum" by F ... At this time, they were incorrectly termed adenoma sebaceum. We now know that the sebaceous glands are only passively involved ...
*  Tubulovillous adenoma
TVAs are considered to have a higher risk of malignant transformation than tubular adenomas. Villous adenoma Colorectal polyp ... Tubulovillous adenoma, TVA, is a type of polyp that grows in the colon and other places in the gastrointestinal tract and ... Tubulovillous adenoma entry in the public domain NCI Dictionary of Cancer Terms This article incorporates public domain ...
*  Villous adenoma
Colorectal cancer Sessile serrated adenoma Tubulovillous adenoma Villous adenoma entry in the public domain NCI Dictionary of ... These adenomas may become malignant (cancerous). Villous adenomas have been demonstrated to contain malignant portions in about ... Villous adenoma is a type of polyp that grows in the colon and other places in the gastrointestinal tract and sometimes in ... Being an adenoma, the mass is covered in columnar epithelial cells. ...
*  Metanephric adenoma
... mimics - allenpress.com. Metanephric adenoma - micrographs - webpathology.com.. ... suggesting that MA is not related to renal cell carcinoma and papillary adenoma. As metanephric adenomas are considered benign ... Metanephric adenoma (MA)is a rare, benign tumour of the kidney, that can have a microscopic appearance similar to a ... Metanephric adenoma is diagnosed histologically. The tumours can be located at upper pole, lower pole and mid-hilar region of ...
*  Canalicular adenoma
In addition to pleomorphic adenoma, the two are the most common tumors of the upper lip. In 95% of cases, canalicular adenoma ... Canalicular adenoma is most likely to occur in older adults around 70 years of age. There is a predilection for gender with ... Canalicular adenoma is characterized as a slow growing, painless swelling, whose diameter can be up to 2 cm. It can be normal ... Canalicular adenoma is a type of benign salivary gland tumor that occurs most often in minor salivary glands. ...
*  Colorectal adenoma
... tubular adenoma tubulovillous adenoma villous adenoma sessile serrated adenoma (SSA) Hardcastle, J. D.; Armitage, N. C. (1984 ... The colorectal adenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal ...
*  Papillary eccrine adenoma
... (also known as "tubular apocrine adenoma")[citation needed] is a cutaneous condition characterized by ... Blasini W, Hu S, Gugic D, Vincek V (2007). "Papillary eccrine adenoma in association with cutaneous horn". Am J Clin Dermatol. ... ISBN 0-7216-2921-0. Laxmisha C, Thappa DM, Jayanthi S (2004). "Papillary eccrine adenoma". Indian J Dermatol Venereol Leprol. ... Jackson EM, Cook J (December 2002). "Mohs micrographic surgery of a papillary eccrine adenoma". Dermatol Surg. 28 (12): 1168-72 ...
*  Basal cell adenoma
... is a rare, low-grade benign salivary gland neoplasm. The most common involved site is the parotid gland, ... González-García, R; Nam-Cha, SH; Muñoz-Guerra, MF; Gamallo-Amat, C (1 March 2006). "Basal cell adenoma of the parotid gland. ...
*  Sessile serrated adenoma
Unlike traditional colonic adenomas (e.g. tubular adenoma, villous adenoma), they do not (typically) have nuclear changes ( ... The surveillance interval is dependent on (1) the number of adenomas, (2) the size of the adenomas, and (3) the presence of ... Intestinal adenomas - halflytely.com. Pathology of Serrated Colon Adenomas - Medscape. ... In gastroenterology, a sessile serrated adenoma (abbreviated SSA), also known as sessile serrated polyp (abbreviated SSP), is a ...
*  Hürthle cell adenoma
... is a rare benign tumor, typically seen in women between the ages of 70 and 80 years old. This adenoma is ... This adenoma is extremely rare; when it occurs, it usually occurs in women. Often the adenoma is harmless but is removed after ... There are three main treatments for Hürthle cell adenomas. Once the adenoma is detected most often the nodules removed to ... "Appearance of Hürthle cell carcinoma soon after surgical extirpation of Hürthle cell adenoma and follicular adenoma of the ...
*  Hyalinizing trabecular adenoma
... (or Hyalinizing trabecular adenoma) is a subtype of thyroid adenoma. Ünlütürk, U; Karaveli, G; ...
*  Carcinoma ex pleomorphic adenoma
Salivary gland Pleomorphic adenoma Di Palma, S. (Jul 2013). "Carcinoma ex pleomorphic adenoma, with particular emphasis on ... Carcinoma ex pleomorphic adenoma, abbreviated ca ex PA, is a type of cancer typically found in the parotid gland. It arises ... Carcinoma ex pleomorphic adenoma is diagnosed by examining it under the microscope with consideration of the individual history ... In approximately 75% of cases ca ex PAs arise in a pleomorphic adenoma that is apparent when the tumour is excised. In the ...
*  Neuroendocrine adenoma middle ear
Neuroendocrine adenoma of the middle ear has gone by several different names, including middle ear adenoma, carcinoid tumor, ... Neuroendocrine adenoma of the middle ear (NAME) is a tumor which arises from a specific anatomic site: middle ear. NAME is a ... amphicrine adenoma, adenocarcinoid, and adenomatoid tumor of middle ear. The various names have created some confusion about ...
Parathyroid adenoma - Wikipedia  Parathyroid adenoma - Wikipedia
A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism; there are very few ... Oftentimes parathyroid adenoma is not diagnosed until found on standard blood-tests that reveal high calcium content in the ... Parathyroid adenoma can be associated with overexpression of the cyclin D1 gene. Hyperparathyroidism is confirmed by blood ... sometimes parathyroid adenomas can be ablated by ethanol injection, guided by ultrasound. Endocrine system Parathyroid disease ...
more infohttps://en.wikipedia.org/wiki/Parathyroid_adenoma
Growth Hormone-Secreting Pituitary Adenoma
     Summary Report | CureHunter  Growth Hormone-Secreting Pituitary Adenoma Summary Report | CureHunter
Growth Hormone-Secreting Pituitary Adenoma: A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH ... Adenoma, Somatotroph; Adenomas, Somatotroph; GH Secreting Pituitary Adenoma; GH-Secreting Pituitary Adenomas; Pituitary Adenoma ... prolactin cell adenomas, melanocorticotroph adenomas and thyrotroph adenomas. ". 01/01/2010 - "Double pituitary adenomas are ... Somatotroph Adenomas; Pituitary Adenoma, GH-Secreting; Pituitary Growth Hormone-Secreting Adenoma; Somatotroph Adenoma ...
more infohttp://www.curehunter.com/public/keywordSummaryD049912-Growth-Hormone-Secreting-Pituitary-Adenoma.do
A mutation and expression analysis of the oncogene BRAF in pituitary adenomas | Archivio Istituzionale della Ricerca  A mutation and expression analysis of the oncogene BRAF in pituitary adenomas | Archivio Istituzionale della Ricerca
We speculated that this same gene may be either mutated at this site, or overexpressed, in pituitary adenomas. DESIGN AND ... B-Raf mRNA was overexpressed in pituitary adenomas compared to normal pituitary, and this was entirely due to overexpression in ... In addition, we investigated B-Raf mRNA expression in normal pituitary (n = 5) and nonfunctioning pituitary adenomas (NFPA) (n ... A mutation and expression analysis of the oncogene BRAF in pituitary adenomas. ...
more infohttps://air.unimi.it/handle/2434/40076
Overgrowth: Missing a Tumor Acromegaly without Imaging Evidence of Pituitary Adenoma and No Ectopic Source: A Case Report |...  "Overgrowth: Missing a Tumor" Acromegaly without Imaging Evidence of Pituitary Adenoma and No Ectopic Source: A Case Report |...
The pituitary adenomas that cause growth hormone excess are usually large and are easily identified on routine MRI imaging of ... Acromegaly without Imaging Evidence of Pituitary Adenoma and No Ectopic Source: A Case Report Nicodemus Ong* and Rosa Allyn Sy ... We report a case of acromegaly with no evidence of a pituitary adenoma and no evidence of an ectopic source after imaging ... 2] Khandelwal D, Khadgawat R, Mukund A, Suri A. Acromegaly with no pituitary adenoma and no evidence of ectopic source. Indian ...
more infohttp://www.asean-endocrinejournal.org/index.php/JAFES/article/view/419/855
Adrenocorticotropin-producing pituitary carcinoma with expression of c-erbB-2 and high PCNA index: A comparative study with...  Adrenocorticotropin-producing pituitary carcinoma with expression of c-erbB-2 and high PCNA index: A comparative study with...
C-erbB-2 staining was present in the cytoplasm of a variable number of cells in 40% of the invasive adenomas (n = 103), while ... A comparative study with pituitary adenomas and normal pituitary tissues. Autor Nose-Alberti, V Mesquita, MIS Martin, L. C. ... When compared to other cases of Cushing's disease (n = 52), other pituitary adenomas (n = 292), and normal pituitary tissues (n ... was also found compared to other ACTH-secreting adenomas (invasive, 3.4 +/- 1.9% vs 1.7 +/- 1.5% in noninvasive) and other ...
more infohttp://repositorio.unifesp.br/handle/11600/25871
GH-secreting pituitary macroadenoma (acromegaly) associated with progressive dental malocclusion and refractory CPAP treatment ...  GH-secreting pituitary macroadenoma (acromegaly) associated with progressive dental malocclusion and refractory CPAP treatment ...
... corticotroph adenomas, which produce adrenocorticotropic hormone ACTH); and gonadotroph adenomas, which produce gonadotropin [1 ... lactotroph adenomas, which produce prolactin; thyrotroph adenomas, which produce thyroid-stimulating hormone (TSH); ... Kovacs K, Horvath E, Vidal S. Classification of pituitary adenomas. J Neurooncol. 2001;54:121-7.View ArticlePubMedGoogle ... Pituitary adenomas are benign neoplasms arising from cells of the anterior pituitary gland and constitute 10-15% of ...
more infohttps://head-face-med.biomedcentral.com/articles/10.1186/s13005-017-0140-6
ASUHAN KEPERAWATAN: Prolactinoma - Causes, Symptoms & Treatments  ASUHAN KEPERAWATAN: Prolactinoma - Causes, Symptoms & Treatments
This tumor is also called by the name of adenoma. Due to this tumor, prolactin hormone is manufactured in large quantities ...
more infohttp://anakkomik.blogspot.com/2010/06/prolactinoma-causes-symptoms-treatments.html
Parathyroid Disease and Surgery (Parathyroidectomy)  Parathyroid Disease and Surgery (Parathyroidectomy)
While adenomas are typically benign, they can be cancerous. Parathyroid adenomas produce the parathyroid hormone without ... Primary hyperparathyroidism is usually the result of tumors called adenomas in the parathyroid gland. ... In approximately 80% of hyperparathyroidism cases, adenomas affect only one of the parathyroid glands. ...
more infohttp://entkidsadults.com/head-and-neck-disorders-and-treatment/parathyroid-disease-and-surgery-parathyroidectomy/
Adenoma - Wikipedia  Adenoma - Wikipedia
An adenoma (from Greek αδένας, adeno-, "gland" + -ώμα, -oma, "tumor") (/ˌædɪˈnoʊmə/; plural adenomas or adenomata /ˌædɪˈnoʊmɪtə ... Hepatic adenomas are a rare benign tumour of the liver, which may present with hepatomegaly or other symptoms. Breast adenomas ... Bronchial adenomas are adenomas in the bronchi. They may cause carcinoid syndrome, a type of paraneoplastic syndrome. A ... A physician's response to detecting an adenoma in a patient will vary according to the type and location of the adenoma among ...
more infohttps://en.wikipedia.org/wiki/Adenoma
Hepatocellular adenoma - Wikipedia  Hepatocellular adenoma - Wikipedia
Hepatocellular adenoma (also known as hepatic adenoma or hepadenoma) is a rare, benign liver tumor. It most commonly occurs in ... The histologic diagnosis of hepatic adenomas can be aided by reticulin staining. In hepatic adenomas, the reticulin scaffold is ... Pregnancy could cause the adenoma to grow faster, so patients with hepatic adenomas should avoid pregnancy.[10] ... "Hepatocellular Adenoma: eMedicine Gastroenterology".. *^ a b c Anthony S. Fauci; Eugene Braunwald; Dennis L. Kasper; Stephen L ...
more infohttps://en.wikipedia.org/wiki/Hepatocellular_adenoma
Pituitary Adenoma | SpringerLink  Pituitary Adenoma | SpringerLink
Diagnosis and treatment of pituitary adenomas: a review. JAMA. 2017;317(5):516-24.CrossRefPubMedGoogle Scholar ... Prevalence of pituitary adenomas. Clin Endocrinol. 2010;72(3):377-82.CrossRefGoogle Scholar ... Okamoto Y, Okamoto F, Hiraoka T, Yamada S, Oshika T. Vision-related quality of life in patients with pituitary adenoma. Am J ... The incidence rate of pituitary adenomas in western Sweden for the period 2001-2011. Eur J Endocrinol. 2014;171(4):519-26. ...
more infohttps://link.springer.com/chapter/10.1007%2F978-981-10-7668-8_41
Bronchial Adenoma | The BMJ  Bronchial Adenoma | The BMJ
Bronchial Adenoma. Br Med J 1954; 1 doi: https://doi.org/10.1136/bmj.1.4875.1362 (Published 12 June 1954) Cite this as: Br Med ...
more infohttp://www.bmj.com/content/1/4875/1362
Pituitary Adenoma - Neurology - MedHelp  Pituitary Adenoma - Neurology - MedHelp
... was found to have Pituitary Adenoma( on CT and MRI), of size .8 x 1 cm, located within the confines of sella Turcica. It is ... Pituitary Adenoma Arifa10 Three weeks ago, my daughter, aged 17 years, was found to have Pituitary Adenoma( on CT and MRI), of ... Pituitary Adenoma. Three weeks ago, my daughter, aged 17 years, was found to have Pituitary Adenoma( on CT and MRI), of size .8 ... For adenoma we are given 2 options to choose from, either to go for surgery( Trans- sphenoidal or through skull) or ...
more infohttps://www.medhelp.org/posts/Neurology/Pituitary-Adenoma/show/351402
adenomas - Wiktionary  adenomas - Wiktionary
Retrieved from "https://en.wiktionary.org/w/index.php?title=adenomas&oldid=45977831" ...
more infohttps://en.wiktionary.org/wiki/adenomas
Hepatocellular adenoma definition | Drugs.com  Hepatocellular adenoma definition | Drugs.com
Definition of hepatocellular adenoma. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and ... Synonym(s): hepatic adenoma. Further information. Always consult your healthcare provider to ensure the information displayed ...
more infohttps://www.drugs.com/dict/hepatocellular-adenoma.html
Hepatocellular Adenoma: Background, Pathophysiology, Epidemiology  Hepatocellular Adenoma: Background, Pathophysiology, Epidemiology
... are also known as hepatic adenomas or liver cell adenomas. They are rare, benign tumors of presumable epithelial origin and ... Hepatocellular adenomas (HCAs) are also known as hepatic adenomas or liver cell adenomas. They are rare, benign tumors of ... encoded search term (Hepatocellular Adenoma) and Hepatocellular Adenoma What to Read Next on Medscape. Related Conditions and ... In addition to a multiplicity of adenomas, hepatic adenomas associated with GSD tend to occur more commonly in men than women ( ...
more infohttps://emedicine.medscape.com/article/170205-overview
Periampullary adenoma causing pancreatitis. | The BMJ  Periampullary adenoma causing pancreatitis. | The BMJ
Periampullary adenoma causing pancreatitis. Br Med J (Clin Res Ed) 1981; 283 :527 ... Periampullary adenoma causing pancreatitis.. Br Med J (Clin Res Ed) 1981; 283 doi: https://doi.org/10.1136/bmj.283.6290.527 ( ...
more infohttp://www.bmj.com/content/283/6290/527.1/peer-review
Pituitary Adenoma Treatment | Moffitt  Pituitary Adenoma Treatment | Moffitt
Moffitt Cancer Center reviews the approaches for treating functioning and nonfunctioning pituitary adenomas. To learn more, ... Nonfunctioning adenomas are often asymptomatic, but may require treatment if they grow large enough to press against a nearby ... Functioning adenomas, on the other hand, produce excessive amounts of hormones that can create imbalances and disrupt various ... Treatment for a pituitary adenoma, or a benign tumor that develops in the pituitary gland, will vary based on the tumor's size ...
more infohttps://moffitt.org/cancers/pituitary-adenoma/treatment/
adenoma | Gut  adenoma | Gut
PTU-038 Predictors of adenoma detection at colonoscopy after bowel scope surveillance K Siau, AC Yew, S Shetty, S Ishaq, S ... Risk stratification of individuals with low-risk colorectal adenomas using clinical characteristics: a pooled analysis Samir ... Modifiable lifestyle factors associated with risk of sessile serrated polyps, conventional adenomas and hyperplastic polyps ... PTH-039 Prevalence of sessile serrated adenomas/polyps in distal colon during screening colonoscopy/flexible sigmoidoscopy: a ...
more infohttps://gut.bmj.com/keyword/adenoma
Bronchial Adenoma | Thorax  Bronchial Adenoma | Thorax
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center's RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
more infohttp://thorax.bmj.com/content/17/1/61
  • Some adenomas grow from epithelial tissue in nonglandular areas but express glandular tissue structure (as can happen in familial polyposis coli). (wikipedia.org)
  • Nonfunctioning adenomas are often asymptomatic, but may require treatment if they grow large enough to press against a nearby nerve or the brain. (moffitt.org)
  • The patient underwent endoscopic transsphenoidal surgery 2 weeks later, and the pathological report indicated gonadotroph adenoma. (springer.com)
  • Visual outcomes after endoscopic endonasal pituitary adenoma resection: a systematic review and meta-analysis. (springer.com)
  • Toxic multinodular goiter (TMNG) encompasses a spectrum of pathologies ranging from a single hyperfunctioning nodule within an enlarged thyroid gland, which has additional normal or nonfunctioning nodules, to multiple hyperfunctiong nodules.Toxic adenoma is more common in women, and can occur at any age, being more frequent between the ages of 30 and 60 years, while TMNG tends to occur at older age. (springer.com)
  • When treatment is necessary, surgery may be recommended to remove a large adenoma (macroadenoma). (moffitt.org)
  • Oftentimes parathyroid adenoma is not diagnosed until found on standard blood-tests that reveal high calcium content in the blood, it can appear in urine tests as well. (wikipedia.org)
  • On 4D-CT parathyroid adenomas typically demonstrate intense enhancement on arterial phase, washout of contrast on delayed phase, and low attenuation on non-contrast imaging. (wikidoc.org)
  • Pituitary adenoma, craniopharyngioma, and Rathke cleft cyst involving both intrasellar and suprasellar regions: differentiation using MRI. (springer.com)