Adenolymphoma: A benign tumor characterized histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid.Parotid Neoplasms: Tumors or cancer of the PAROTID GLAND.Adenoma, Pleomorphic: A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)Salivary Gland Neoplasms: Tumors or cancer of the SALIVARY GLANDS.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Parotid DiseasesCarcinoma, Mucoepidermoid: A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)T-Lymphocytes, Regulatory: CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells.Forkhead Transcription Factors: A subclass of winged helix DNA-binding proteins that share homology with their founding member fork head protein, Drosophila.Disclosure: Revealing of information, by oral or written communication.Truth Disclosure: Truthful revelation of information, specifically when the information disclosed is likely to be psychologically painful ("bad news") to the recipient (e.g., revelation to a patient or a patient's family of the patient's DIAGNOSIS or PROGNOSIS) or embarrassing to the teller (e.g., revelation of medical errors).Interleukin-2 Receptor alpha Subunit: A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN to form a high affinity receptor for INTERLEUKIN-2.CD4-Positive T-Lymphocytes: A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.T-Lymphocyte Subsets: A classification of T-lymphocytes, especially into helper/inducer, suppressor/effector, and cytotoxic subsets, based on structurally or functionally different populations of cells.Branchioma: A tumor derived from branchial epithelium or branchial rests. (Dorland, 27th ed)Neck: The part of a human or animal body connecting the HEAD to the rest of the body.Thyroiditis, Subacute: Spontaneously remitting inflammatory condition of the THYROID GLAND, characterized by FEVER; MUSCLE WEAKNESS; SORE THROAT; severe thyroid PAIN; and an enlarged damaged gland containing GIANT CELLS. The disease frequently follows a viral infection.Biological Science Disciplines: All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.Audiovisual Aids: Auditory and visual instructional materials.Computer-Assisted Instruction: A self-learning technique, usually online, involving interaction of the student with programmed instructional materials.Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)Hepatitis, Infectious Canine: A contagious disease caused by canine adenovirus (ADENOVIRUSES, CANINE) infecting the LIVER, the EYE, the KIDNEY, and other organs in dogs, other canids, and bears. Symptoms include FEVER; EDEMA; VOMITING; and DIARRHEA.Dog Diseases: Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.Thoracica: A superorder of marine CRUSTACEA, free swimming in the larval state, but permanently fixed as adults. There are some 800 described species, grouped in several genera, and comprising of two major orders of barnacles: stalked (Pedunculata) and sessile (Sessilia).Molting: Periodic casting off FEATHERS; HAIR; or cuticle. Molting is a process of sloughing or desquamation, especially the shedding of an outer covering and the development of a new one. This phenomenon permits growth in ARTHROPODS, skin renewal in AMPHIBIANS and REPTILES, and the shedding of winter coats in BIRDS and MAMMALS.Water Movements: The flow of water in enviromental bodies of water such as rivers, oceans, water supplies, aquariums, etc. It includes currents, tides, and waves.GermanyDogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)RNA, Double-Stranded: RNA consisting of two strands as opposed to the more prevalent single-stranded RNA. Most of the double-stranded segments are formed from transcription of DNA by intramolecular base-pairing of inverted complementary sequences separated by a single-stranded loop. Some double-stranded segments of RNA are normal in all organisms.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Nucleic Acid Conformation: The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.RNA: A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.RNA, Viral: Ribonucleic acid that makes up the genetic material of viruses.RNA, Small Interfering: Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Hyalin: A clear, homogenous, structureless, eosinophilic substance occurring in pathological degeneration of tissues.Adenoma: A benign epithelial tumor with a glandular organization.Sweat Gland NeoplasmsAdenoma, Liver Cell: A benign epithelial tumor of the LIVER.Epithelial Cells: Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.Carcinoma, Basal Cell: A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)Neoplasms, Basal Cell: Neoplasms composed of cells from the deepest layer of the epidermis. The concept does not refer to neoplasms located in the stratum basale.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Cat Diseases: Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.Skin Neoplasms: Tumors or cancer of the SKIN.Mucopolysaccharidosis III: Mucopolysaccharidosis characterized by heparitin sulfate in the urine, progressive mental retardation, mild dwarfism, and other skeletal disorders. There are four clinically indistinguishable but biochemically distinct forms, each due to a deficiency of a different enzyme.Caenorhabditis elegans: A species of nematode that is widely used in biological, biochemical, and genetic studies.Caenorhabditis elegans Proteins: Proteins from the nematode species CAENORHABDITIS ELEGANS. The proteins from this species are the subject of scientific interest in the area of multicellular organism MORPHOGENESIS.Caenorhabditis: A genus of small free-living nematodes. Two species, CAENORHABDITIS ELEGANS and C. briggsae are much used in studies of genetics, development, aging, muscle chemistry, and neuroanatomy.Genes, Helminth: The functional hereditary units of HELMINTHS.Helminth Proteins: Proteins found in any species of helminth.Vulva: The external genitalia of the female. It includes the CLITORIS, the labia, the vestibule, and its glands.Vacuoles: Any spaces or cavities within a cell. They may function in digestion, storage, secretion, or excretion.

Bone morphogenetic protein-6 is a marker of serous acinar cell differentiation in normal and neoplastic human salivary gland. (1/66)

Bone morphogenetic protein (BMP-6, also known as vegetal-pale-gene-related and decaplentaplegic-vegetal-related) is a member of the transforming growth factor-beta superfamily of multifunctional signaling molecules. BMP-6 appears to play various biological roles in developing tissues, including regulation of epithelial differentiation. To study the possible involvement of BMP-6 in normal and neoplastic human salivary glands, we compared its mRNA and protein expression in 4 fetal and 15 adult salivary glands and in 22 benign and 32 malignant salivary gland tumors. In situ hybridization and Northern blot analysis indicated that BMP-6 transcripts are expressed at low levels in acinar cells of adult submandibular glands but not in ductal or stromal cells. BMP-6 was immunolocated specifically in serous acini of parotid and submandibular glands. None was found in primitive fetal acini or any other types of cell in adult salivary glands, including mucous acini and epithelial cells of intercalated, striated, and excretory ducts. All 16 cases of acinic cell carcinoma consistently exhibited cytoplasmic BMP-6 staining in the acinar tumor cells. Other cell types in these tumors, including intercalated duct-like cells, clear, vacuolated cells, and nonspecific glandular cells, exhibited no cytoplasmic BMP-6 staining. Other benign and malignant salivary gland tumors lacked BMP-6 immunoreactivity, except in areas of squamous differentiation. The results indicate that in salivary glands, BMP-6 expression is uniquely associated with acinar cell differentiation and suggest that BMP-6 may play a role in salivary gland function. More importantly, our experience of differential diagnostic problems related to salivary gland tumors suggests that the demonstration of consistent and specific BMP-6 immunoreactivity in acinic cell carcinoma is likely to be of clinical value.  (+info)

Warthin-like tumor of the thyroid a case report. (2/66)

A case of Warthin-like tumor of the thyroid (WaLTT) with cervical lymph node metastasis is presented. The problems of the FNA diagnosis of this type of tumor is discussed as well as the histogenesis, nature and behaviour of this peculiar tumor.  (+info)

Follicle center lymphoma and Warthin tumor involving the same anatomic site. Report of two cases and review of the literature. (3/66)

We report 2 cases of follicle center non-Hodgkin lymphoma (NHL) and Warthin tumor involving the same site. Case 1 is a 68-year-old woman with Warthin tumor and grade 1 follicular NHL involving a periparotid lymph node. She had localized NHL and was treated with radiation therapy; dissemination developed 54 months later. Case 2 is a 55-year-old man with a 17-year history of a parotid mass with gradual enlargement during the last 5 years. Surgical excision revealed Warthin tumor and grade 1 follicular NHL involving the right parotid gland and surrounding lymph nodes. Immunohistochemical studies supported the diagnosis of NHL in both cases; the neoplasms were positive for CD20 and BCL-2 and negative for CD3. Polymerase chain reaction analysis done on paraffinembedded tissue of case 1 revealed monoclonal immunoglobulin heavy chain gene rearrangement and bcl-2/JH fusion DNA sequences diagnostic of the t(14;18)(q32;q21). The small size of the Warthin tumor in case 1, clearly arising in lymph node, supports the hypothesis that Warthin tumor arises from heterotopic salivary gland ducts within lymph nodes. The localized NHL in both patients suggests that the NHL initially arose in the lymph node involved by Warthin tumor, and, thus, the Warthin tumor may have provided a source of long-term antigenic stimulation from which a monoclonal B-cell population subsequently arose.  (+info)

Mucoepidermoid carcinoma involving Warthin tumor. A report of five cases and review of the literature. (4/66)

We describe 5 cases of mucoepidermoid carcinoma (MEC) involving Warthin tumor (WT) of the parotid gland. The WT size ranged from 1.7 to 6.0 cm. The MECs were much smaller, 0.3 to 1.7 cm. In 3 cases, the WT completely surrounded the MEC, and in 2 cases neither WT nor MEC surrounded the other. Each MEC was low grade, 3 grade I and 2 grade II. One MEC had evidence of vascular invasion. All patients underwent partial or subtotal parotidectomy with negative resection margins. Clinical follow-up (range, 8-52 months) for 3 patients showed no evidence of recurrence. The pathogenetic relationship between WT and MEC in these cases is uncertain. In 4 cases, foci of squamous or mucous metaplasia were found in the WT component, associated with mild cytologic atypia in 3 tumors. However, a direct transition from WT to MEC was not identified. In 1 case, MEC was present 45 months before WT, suggesting that the recurrent MEC involved WT coincidentally. The small size and low grade of the MEC and the negative resection margins most likely explain the good outcome for the 3 patients with clinical follow-up data available.  (+info)

Guanylin and functional coupling proteins in the human salivary glands and gland tumors : expression, cellular localization, and target membrane domains. (5/66)

Cystic fibrosis transmembrane conductance regulator (CFTR)-mediated secretion of an electrolyte-rich fluid is a major but incompletely understood function of the salivary glands. We provide molecular evidence that guanylin, a bioactive intestinal peptide involved in the CFTR-regulated secretion of electrolyte/water in the gut epithelium, is highly expressed in the human parotid and submandibular glands and in respective clinically most relevant tumors. Moreover, in the same organs we identified expression of the major components of the guanylin signaling pathway, ie, guanylin-receptor guanylate cyclase-C, cGKII, and CFTR, as well as of the epithelial Cl(-)/HCO(3)(-) anion exchanger type 2 (AE2). At the cellular level, guanylin is localized to epithelial cells of the ductal system that, based on its presence in the saliva, is obviously released into the salivary gland ducts. The guanylin-receptor guanylate cyclase-C, cGKII, CFTR, and AE2 are all confined exclusively to the apical membrane of the same duct cells. These findings implicate guanylin as intrinsic regulator of electrolyte secretion in the salivary glands. We assume that duct epithelial cells synthesize and release guanylin into the saliva to regulate electrolyte secretion in the ductal system by an intraductal luminocrine signaling pathway. Moreover, the high expression of guanylin in pleomorphic adenoma and Warthin tumors (cystadenolymphoma), the most common neoplasms of salivary glands, predicts guanylin as a significant marker in tumor pathology.  (+info)

Lymphadenoma arising in the parotid gland: a case report. (6/66)

We report a case of lymphadenoma arising in the parotid gland. A 53-year-old female patient presented with a mass in the parotid gland. Grossly, it was a well-demarcated solid mass measuring 3 cm in diameter. Microscopic examination revealed many cysts or duct-like structures in the background of the prominent lymphoid stroma, confirming a diagnosis of lymphadenoma. This particular case was thought to have arisen from an intraparotid lymph node. Lymphadenoma is a rare benign neoplasm of the salivary gland with partial resemblance to other salivary gland tumors, such as Warthin's tumor, cystadenoma, sebaceous lymphadenoma or mucoepidermoid carcinoma. Therefore proper recognition of this rare entity is warranted to avoid confusion in the diagnosis.  (+info)

Poorly differentiated carcinoma arising from adenolymphoma of the parotid gland. (7/66)

BACKGROUND: There is only one previous case report of a poorly differentiated carcinoma arising from an adenolymphoma of the parotid gland (Warthin's tumour). The absence of clinical symptoms, and the aspecificity of the radiological pattern make the diagnosis very difficult. CASE PRESENTATION: We here report the case of a 73-year-old man with Warthin's tumour who was brought to our attention because of a swelling in the parotid region. CONCLUSIONS: In this case with an atypical clinical presentation, the intra-operative examination of a frozen section of the parotid mass allowed us to diagnose the malignant tumour correctly and consequently undertake its radical excision.  (+info)

Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases. (8/66)

Salivary gland tumors constitute a highly heterogeneous histopathologic group. There are few epidemiological studies of large series of benign and malignant salivary gland tumors in Brazil. MATERIAL AND METHODS: Hospital records of 124 patients with salivary gland tumors diagnosed from January 1993 to December 1999 were reviewed. The patients were analyzed according to gender, age, size, location, and histopathology of the tumor. RESULTS AND CONCLUSIONS: Patients with benign and malignant tumors presented with a mean age of 47.7 and 48.8 years, respectively. The frequency of benign tumors was 80% (n = 99) and malignant tumors 20% (n = 25). Tumors were localized in the parotid gland 71% (n = 88), in the submandibular gland 24% (n = 30), and in the minor salivary glands 5% (n = 6). The most common benign tumors were pleomorphic adenoma in 84% (n = 84) and Warthin's tumor in 13% (n = 13). Among malignant tumors, mucoepidermoid carcinoma was the most common in 52% (n = 13), adenoid cystic carcinoma occurred in 20% (n = 5), and carcinoma ex pleomorphic adenoma was detected in 12% (n = 3).  (+info)

Sebaceous lymphadenoma is a benign tumour of the salivary gland. Sebaceous lymphadenoma is a tissue diagnosis, e.g. salivary gland biopsy. It may be confused with a number of benign and malignant neoplasms, including Warthin tumour, mucoepidermoid carcinoma and sebaceous lymphadenocarcinoma. The treatment is simple excision and exclusion of a malignant neoplasm. Lymph node Lymphoma Salivary gland neoplasm Mishra, A.; Tripathi, K.; Mohanty, L.; Nayak, M. "Sebaceous lymphadenoma of the parotid gland". Indian J Pathol Microbiol. 54 (1): 131-2. doi:10.4103/0377-4929.77364. PMID 21393895. While, B.; Whiteside, OJ.; Desai, V.; Gurr, P. (Aug 2010). "Sebaceous lymphadenoma: a case report and review of the literature". Ear Nose Throat J. 89 (8): E22-3. PMID 20737364 ...
Warthins tumor primarily affects older individuals (age 60-70 years). There is a slight male predilection according to recent studies. The tumor is slow growing, painless, and usually appears in the tail of the parotid gland near the angle of the mandible. In 5-14% of cases, Warthins tumor is bilateral, but the two masses usually are at different times. Warthins tumor is highly unlikely to become malignant. ...
Tian Z, Li L, Wang L, Hu Y, Li J. Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population. Int J Oral Maxillofac Surg 2010;39: 235-42. Chapnik JS. The controversy of Warthins tumor. Laryngoscope 1983; 93: 695-716. Naujoks C, Sproll C, Singh DD, Heikaus S, Depprich R, Kübler NR et al. Bilateral multifocal Warthins tumors in upper neck lymph nodes. Report of a case and brief review of the literature. Head Face Med. 2012; 3: 8-11. Maiorano E, Lo Muzio L, Favia G, Piattelli A. Warthins tumour: a study of 78 cases with emphasis on bilaterality, multifocality and association with other malignancies. Oral Oncol. 2002; 38: 35-40. Teymoortash A, Krasnewicz Y, Werner JA. Clinical features of cystadenolymphoma (Warthins tumor) of the parotid gland: a retrospective comparative study of 96 cases. Oral Oncol 2006; 42: 569-73. Singer MI, Applebaum EL, Loy KD. Heterotopic salivary tissue in the neck. Laryngoscope 1979; 89: ...
Ultrasound images demonstrate a well demarcated, hypoechoic mass or a solid mass with multiple anechoic internal areas. On CT, Warthin tumors are homogeneous, enhancing soft tissue densities that contain no calcification. If calcifications are present in a benign appearing parotid mass, the diagnosis of pleomorphic adenoma should be favored. Warthin tumors are traditionally located in the posterior aspect of the tail of the parotid gland but the tumors have been known to arise from periparotid lymph nodes. Cyst formation is common and the larger the tumor the greater the chance for cystic change. On MR imaging, the tumors have low T1 and high T2 signal (similar to pleomorphic adenomas). Warthin tumors are rich in mitochondrium and therefore will accumulate Tc-99m pertechnetate on salivary scintigraphy. Unfortunately, oncocytomas and the extremely rare oncocytic carcinoma both accumulate pertechnetate as well. Imaging findings that suggest a malignant parotid mass include; irregular margins, ...
To our knowledge, few reports on the imaging of oncocytic neoplasms of the salivary glands have been published, owing to the rarity of the condition. Sakai et al1 reported an oncocytoma in the deep lobe of the parotid gland that was well-defined and solid on CT. It demonstrated decreased signal intensity on both T1- and T2-weighted MR images, attributed to the high cellularity and low free water content. According to the authors, Warthin tumor, which is a common benign parotid gland tumor in patients older than 60 years, can be differentiated from oncocytoma by its MR imaging appearance. Warthin tumors conversely demonstrate decreased signal intensity on T1-weighted images and increased signal intensity on T2-weighted images.1 Both Warthin tumors and oncocytomas show intense uptake of the nuclide on technetium-Tc99m pertechnetate radionuclide scans of the salivary glands.2. The histomorphologic findings of oncocytes include an enlarged polygonal shape with granular intensely acidophilic ...
Luminita Daguci(1), Cristiana Simionescu(2), C. Daguci(1), Marilena Bataiosu(3), L. P. Dragomir(1) (1) Restorative Dentistry Department , UMF Craiova (2) Pathology Department, UMF Craiova (3) Odontology Department, UMF Craiova Abstract The study includes 16 cases of Warthin s tumor in a period of 4 years (2004-2008). The tumors were diagnosed at patients of VII decade, most of them smoker. The studies of Warthin s tumor macroscopic morphological parameters
K Song, JD Cotelingam, M Lowery-Nordberg, W Sun: Characterization of the lymphoid stroma in Warthins tumor of salivary gland by immunohistochemistry, heavy chain gene and BCL-2 gene rearrangement. Am J Transl Res 2009;1:211-216. ...
Paraneoplastic syndromes.. Pathology and tumours of the naso-pharyngeal region: general features; specifically: naso-pharyngeal carcinoma.. Larynx: general features; specifically: nodules and polyps of the vocal cords; solitary papilloma and papillomatosis; Laryngeal carcinoma and precursor lesions.. Diseases of the Thymus. Developmental disorders.. Thymic hyperplasia.. Thymomas.. (A, AB, B1, B2, B3, C).. Thymic carcinoid.. Salivary gland pathology. Pleomorphic adenoma, Warthin tumor; acinic cell carcinoma; mucoepidermoid carcinoma; adenoid-cystic carcinoma; benign and malignant lympho-epithelial lesions. Cysts of the head and neck region.. Diseases of the Gastro-Intestinal system. Esophageal diseases. Pathology and pathogenesis of: esophagitis, Barretts esophagus, squamous carcinoma and adenocarcinoma of the esophagus. Non neoplastic gastric diseases. Pathology and pathogenesis of: gastritis (acute and chronic) and gastric ulcer (peptic and acute). Ménétrieres disease.. Tumor and tumorlike ...
Clinical Findings: Small clonal B-cells populations (SCBP) also known as monoclonal B-cell lymphocytosis was found as part of the workup for an idiopathic thrombocytopenia and lead ultimately to the diagnosis of parotid primary follicular lymphoma coexisting with Warthin tumor involving the bone marrow in a small extent and oncocytic papilloma located in the maxillary sinus ...
TY - JOUR. T1 - A study on seventy-eight cases of parotid tumor. AU - Suzuki, Takahiro. AU - Ikushima, Hiroyuki. AU - Kakuta, Risako. AU - Noguchi, Naoya. AU - Ogura, Masaki. AU - Ogawa, Takenori. AU - Katori, Yukio. AU - Shoji, Fumi. AU - Ohta, Nobuo. PY - 2017. Y1 - 2017. N2 - We reviewed 78 cases of parotid gland tumors treated at our hospital over the past 2 years and 5 months. Benign tumors were observed in 65 patients (36 males and 29 females), and malignant tumors were observed in 13 patients (4 males and 9 females). The average patient age was 50 years old for the cases with benign tumors and 65 years old for the cases with malignant tumors. The most common benign tumor was pleomorphic adenoma, followed by Warthins tumor. The most common malignant tumor was mucoepidermoid carcinoma. The sensitivity/specificity/accuracy of preoperative fine-needle aspiration cytology (FNA) were 27.3%, 96.8%, and 86.5%, respectively, while those of MRI were 84.6%, 86.2%, and 85.9% when an unsharp margin ...
Author of 150 articles dealing with mustard gas poisoning (with A.S. Warthin), neoplasms, TB, lead and alcoholic blastophthoria, the hemolymph nodes, hematology, biological aspects of the aging process, developmental disturbances, forensic medicine, causal factors in lung cancer (a text), and the history of medicine. ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
TY - JOUR. T1 - Oncocytic variant of mucoepidermoid carcinoma of submandibular gland. T2 - An unusual clinical and morphological entity. AU - Krishnanand, Geetha. AU - Kaur, Manpreet. AU - Rao, Ravikala V.. AU - Monappa, Vidya. PY - 2007/7/1. Y1 - 2007/7/1. N2 - In this case report we describe a rare tumor - Oncocytic variant of Mucoepidermoid carcinoma of the submandibular salivary gland with a review of the literature. Oncocytic metaplasia in salivary glands is a benign change that is associated with increasing age and also seen in a few salivary gland neoplasms, which include oncocytoma, Warthins tumor, and the rare, oncocytic carcinoma. Oncocytic differentiation in mucoepidermoid carcinoma (MEC) is uncommon. Only twelve well-documented cases of oncocytic MEC have been reported previously all of which occurred in the parotid gland. To the best of our knowledge this is the first case of oncocytic mucoepidermoid carcinoma involving the submandibular salivary gland. The recognition of this ...
Cell phone use has been linked to tumors once again - this time by an Israeli study that found that frequent cell phone users were more likely to develop parotid gland tumors than the population as a whole. The Israeli study is just the latest research to find a connection between cell phone use and a serious <"http://www.yourlawyer.com/practice_areas/diseases">disease. The cell phone tumor study, which is being published today in the "American Journal of Epidemiology", is sure to catch the attention of anyone who spends a great deal of time glued to their cell phone.. The parotid gland is the largest of the salivary glands. The Israeli study looked at 402 adults with benign parotid gland tumors and 58 others who had malignant tumors of the parotid gland diagnosed in Israel from 2001-2003. According to the researchers, people who spent more than 22 hours a month on their cell phones where 50-percent more likely to develop cancer of the parotid gland than those who used the phones less often. The ...
Parotid tumors are an abnormal growth of cells formed in the parotid glands causing partial or permanent paralysis of the facial nerves.
Synonyms for adenomatoid in Free Thesaurus. Antonyms for adenomatoid. 7 words related to adenoma: benign tumor, benign tumour, nonmalignant neoplasm, nonmalignant tumor, nonmalignant tumour, fibroadenoma, lymphadenoma. What are synonyms for adenomatoid?
Adenoid cystic carcinoma: Tends to infiltrate perineural spaces and causes pain. (This well have to remember, unless you submit us a mnemonic! =D ) ...
Extracapsular dissection can be an effective and low-risk method for removing benign, supercial parotid tumors that are less than 4 cm. ...
TY - JOUR. T1 - Widespread cutaneous metastases from acinic cell carcinoma 20 years after primary presentation. AU - Varsegi, Mary F.. AU - Ravis, Scott M.. AU - Hattab, Eyas M.. AU - Henley, John D.. AU - Billings, Steven D.. PY - 2008/6. Y1 - 2008/6. N2 - Acinic cell carcinoma is a rare, low-grade malignant salivary gland neoplasm. Approximately, 20% of patients experience local recurrence and 10% distant metastasis, often many years after initial presentation. We present a case of widespread cutaneous metastasis from acinic cell carcinoma arising in a 59-year-old woman with a history of acinic cell carcinoma of the parotid gland 20 years prior to her cutaneous disease. To our knowledge, is the first report of widespread cutaneous metastasis from acinic cell carcinoma.. AB - Acinic cell carcinoma is a rare, low-grade malignant salivary gland neoplasm. Approximately, 20% of patients experience local recurrence and 10% distant metastasis, often many years after initial presentation. We present a ...
E-cadherin is a calcium dependent cell adhesion molecule, important in cell to cell interactions in epithelial tissues. The present study examined E-cadherin expression in normal salivary glands, pleomorphic adenoma, Warthins tumor, mucoepidermoid carcinoma, acinic cell carcinoma, adenoid cystic carcinoma and adenocarcinoma of salivary glands in paraffin sections using a monoclonal antibody (5H9). This study is firstly reported E-cadherin expression in the salivary gland and tumors.,BR,In normal submandibular and parotid gland, E-cadherin staining was confined to the cell membrane of acinar and ductal cells. In excretory ducts, high columnar cells showed the strongest reaction at the basal aspect and ductal basal cells were weakly positive or negative, the basement membrane zone lacked staining. No E-cadherin reaction was observed in modified myoepithelial cells and plasmacytoid cells. In pleomorphic adenoma and mucoepidermoid carcinoma, E-cadherin was positive at the lateral cell membrane or ...
1 Medicine student at Otorhinolaringoiatric department at San Pier Damiano Hospital, Faenza (Ravenna), Italy. 2 Head of Otorhinolaringoiatric dept. at San Pier Damiano Hospital, via Portisano 1, 48018 Faenza (Ravenna), Italy. ABSTRACT. Inflammatory pseudotumor of the parotid gland is a benign clinical finding of unknown origin, rarely reporter in literature, with only about twelve cases reported. Clinique and radiograph profiles are similar, and often confuse, with the ones of malign tumors, and only histological investigation can discriminate it. In our report, we describe a case of inflammatory pseudotumor of parotid gland in a 53 years old man, HIV and HCV positive, who accessed to our department for surgical excision of a right parotid mass. Ultrasound, CT scan and preoperatory examination showed a nodularity with regular edge propending for Warthin tumor diagnosis. Histologic examination of surgical excision concluded for a proliferative fibrous lesion with inflammatory components and ...
NOTOC__ {{Acinic cell carcinoma}} {{CMG}}; {{AE}} {{RG}} == Overview == There are no established measures for the [[primary prevention]] of [[acinic cell carcinoma]]. == Primary Prevention == There are no established measures for the [[primary prevention]] of [[acinic cell carcinoma]]. ==References== {{Reflist,2}} {{WH}} {{WS ...
TY - JOUR. T1 - Histopathologic, immunophenotypic and cytogenetic features of pulmonary mucoepidermoid carcinoma. AU - Roden, Anja. AU - García, Joaquín J.. AU - Wehrs, Rebecca N.. AU - Colby, Thomas V.. AU - Khoor, Andras. AU - Leslie, Kevin O.. AU - Chen, Longwen. PY - 2014/1/1. Y1 - 2014/1/1. N2 - Pulmonary mucoepidermoid carcinoma is an uncommon but distinctive manifestation of mucoepidermoid carcinoma. Pulmonary mucoepidermoid carcinoma occurs in adults and children and can cause diagnostic problems, especially in small biopsies. Few studies have characterized the histologic and immunophenotypic features of pulmonary mucoepidermoid carcinoma. t(11;19)(q21;p13) is considered disease-defining for mucoepidermoid carcinoma; its significance in pulmonary mucoepidermoid carcinoma warrants further study. Forty three pulmonary mucoepidermoid carcinomas were re-reviewed and graded according to the Brandwein grading system for mucoepidermoid carcinoma. Four cases were excluded because of a split ...
Discussion: Parotid gland neoplasms are quite rare in the pediatric population but when such a lesion is encountered, a higher percentage (40-50%) will be malignant when compared to the adult population (25-35%); therefore, parotid neoplasms in children must be approached with suspicion (1). The mean age at which malignant parotid gland neoplasms occur in the pediatric population is 13.2 years (2). Acinic cell carcinoma (ACC) accounts for an appreciable number of pediatric parotid malignancies; in fact, it is the second most common malignant parotid tumor in this population followed by mucoepidermoid carcinoma (3). Nasse first described the lesion in a 1892 publication in which four cases of parotid adenomas were described (4). Due to the similarity of the tumor cells to normal salivary tissue, the lesions were initially regarded as benign. The benignity of the lesion was questioned in 1953 when Buxton et al. reported three cases of ACC with verified distant metastases (5). Therefore, the lesion ...
Salivary gland tumors most commonly occur in the parotid gland, accounting nearly 85% of all salivary gland tumors. But, 25% of parotid tumors are malignant (cancerous).. Pleomorphic adenoma is the most common type of benign salivary gland tumor. It is typically a slow growing tumor and occur most often in the parotid gland. It is also known as mixed tumor which describes its pleomorphic appearance as opposed to its dual origin from epithelial and myoepithelial elements.. The tumor is usually solitary and presents as a slow growing, painless and firm singular nodal mass. It is usually mobile unless found in the palate and can cause atrophy of the mandibular ramus when located in the parotid gland.. ...
So-called acinic cell carcinoma of the breast arises from microgladular adenosis and is not a distinct entity.. Mod Pathol. 2017 Oct;30(10):1504. Authors: Rosen PP. PMID: 28972583 [PubMed - in process]. ...
Free Online Library: Sarcoidosis presenting as a solitary parotid mass: an uncommon but real diagnostic challenge.(LETTERS TO THE EDITOR, Letter to the editor) by Ear, Nose and Throat Journal; Health, general Autoantibodies
Mucoepidermoid carcinoma is one of the most common malignancies of the salivary glands. Central mucoepidermoid carcinomas are extremely rare in the jaws, representing abo..
The parotid is a gland near the ear. It helps produce and control the release of saliva. If a tumor forms in the parotid gland, it can press on the facial nerve, causing discomfort and pain. Part or all of the face may be weak or paralyzed. To treat a parotid tumor, part or all of the gland is removed. This surgery is called parotidectomy. This sheet explains the surgery and what to expect.
Cavitary mucoepidermoid carcinoma of lung with metastases in skeletal muscles as presenting features: a case report and review of the literature.: Mucoepidermoi
Symptoms of Mucoepidermoid including 8 medical symptoms and signs of Mucoepidermoid, alternative diagnoses, misdiagnosis, and correct diagnosis for Mucoepidermoid signs or Mucoepidermoid symptoms.
Question - Hi, I have an pleomorphic adenoma which has stayed the same - 6F. Find the answer to this and other Medical questions on JustAnswer
TY - JOUR. T1 - Pleomorphic adenoma with extensive adipose content. AU - Jin, Y. T.. AU - Lian, J. D.. AU - Yan, J. J.. AU - Hwang, T. Z.. AU - Tsai, S. T.. PY - 1996/1/1. Y1 - 1996/1/1. UR - http://www.scopus.com/inward/record.url?scp=0030058826&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0030058826&partnerID=8YFLogxK. U2 - 10.1046/j.1365-2559.1996.t01-2-258289.x. DO - 10.1046/j.1365-2559.1996.t01-2-258289.x. M3 - Article. C2 - 8838128. AN - SCOPUS:0030058826. VL - 28. SP - 87. EP - 89. JO - Histopathology. JF - Histopathology. SN - 0309-0167. IS - 1. ER - ...
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Parotid Gland Acinic Cell Carcinoma (Acinic Cell Carcinoma of Parotid): Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis.
Definition of auricular nerve, great in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is auricular nerve, great? Meaning of auricular nerve, great as a legal term. What does auricular nerve, great mean in law?
Looking for the list of best Parotidectomy Hospitals in Mathura within your budget. Contact Us at Vaidam for the right guidance and list of Parotidectomy Hospitals in
A 75-year-old man presented with a left ear lobule melanoma and was found, on examination, to have a concurrent right parotid mass and bilateral cervical lymphadenopathy. A CT scan of the neck confirmed a 2-cm right superficial parotid mass containing both solid and cystic components without any pathognomonic characteristics, as well as bilateral cervical lymphadenopathy with multiple 2- to 3-cm lymph nodes. FNA biopsy of the parotid mass was consistent with carcinoma, whereas FNA samples from the cervical lymph nodes were non-diagnostic.. ...
C.C. Mirestean, Roxana Irina Iancu, C. Buzea, D.T. Iancu. Abstract. Cystic adenoid carcinoma is a rare tumor accounting for less than 1% of all malignant tumors of the head and neck. The presence of another synchronous cancer in the head and neck region is so much a rare case. We present the case of a patient diagnosed with locally advanced neoplasm of the right parotid gland with invasion in the mandible for which surgical treatment was performed. During the post-surgical hospitalization, the patient presented respiratory dysfunction caused by a bulky tumor of the thyroid gland, for which the pathology proved a micro papillary carcinoma. Evidence of a resection margin in contact with tumor of the parotid gland tumor made it necessary a multidisciplinary approach including adjuvant radiotherapy. The patient was also consulted in a nuclear medicine department for metabolic radiation therapy for thyroid cancer. Radiation therapy is part of the adjuvant treatment of head and neck cancers, the risk ...
Pleomorphic adenoma is the most common salivary gland tumor on the head and neck region [1]. Metastasizing pleomorphic adenoma is a rarely detected form of clinic antity [2,3]. According to the World…
Introduction The exact incidence of Helicobacter pylori (HP) in childhood is unknown. There is a causal link between HP and development of peptic ulcers, gastric adenocarcinoma and lymphoma. However there is little evidence and guidance on the clinical management of HP in children. The North American Society for Paediatric Gastroenterology and Nutrition report there is no compelling evidence to treat children colonised with HP without histological evidence of gastritis. This reflects the current pathophysiological understanding of cancer development, where inflammation secondary to infection is believed to be the driver of dysplasia and cancer. In our tertiary referral centre current practice stains all paediatric gastric biopsies with Haematoxylin and Eosin stain (H+E) as well as Warthin Starry (WS) stain, specifically for HP-like organisms. The aim of this study was to investigate the incidence of HP infection in children undergoing endoscopy. We also examined the routine use of special ...
Diagnosis of low- or intermediate-grade tumors is associated with significantly better overall survival and disease-free survival in patients with mucoepidermoid carcinoma (MEC) of the salivary glands, while advanced disease stage and perineural invasion are the most significant indicators of poor prognosis.
Learn more about Parotidectomy at Memorial Hospital DefinitionReasons for ProcedurePossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
Dr.Meenesh Juvekar. M.S (ENT), D.N.B, D.O.R.L, M.N.A.M.S (Ear-Nose-Throat & Head Neck surgeon) Call 91+022-25271150 for appointment
Adenolipoma refers to a variant of a lipoma with entrapped eccrine or, rarely, apocrine units. We present 5 cases of cutaneous adenolipoma to demonstrate the spectrum of changes in the lipomatous and epithelial components. The cases include 3 lesions
The proto-oncogene, pleomorphic adenoma gene-like 2 (PLAGL2), is implicated in a variety of cancers including acute myeloid leukemia (AML), malignant glioma, colon cancer, and lung adenocarcinoma. There is additional evidence that PLAGL2 can function
An Unusual Variant of a Common Palatal Salivary Gland Tumor: Case Report of a Pleomorphic Adenoma with Significant Lipomatous Metaplasia ...
This page was last edited 02:43, 27 November 2017 by mahshid mir. Based on work by Jyostna Chouturi, Aditya Govindavarjhulla and Varun Kumar ...
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Cleanup crews in northern China were scrambling Thursday to absorb 60 tons of toxic coal tar accidentally dumped into a river before it reaches a reservoir serving 10 million people, state media said.
Adenolymphoma of the parotid gland, or papillary cystadenoma lymphomatosum, is better known as "Warthin's tumor"; he described ...
Other serious sequelae include sialolithiasis of the submandibular gland and adenolymphoma of the parotid gland. The ...
Warthin tumour, monomorphic adenoma, adenolymphoma. This Warthin's tumor presented as a parotid mass in a middle-aged male, who ...
... adenolymphoma) more in males than in females. Their importance is in relation to their anatomical position and tendency to grow ...
... adenolymphoma MeSH C04.557.435.090 --- adenoma, pleomorphic MeSH C04.557.435.110 --- adenomyoma MeSH C04.557.435.135 --- ...
... carcinoma Mixed adenocarcinoma and squamous cell carcinoma Mixed adenocarcionma and epidermoid carcinoma M8561/0 Adenolymphoma ...
Warthin tumour, monomorphic adenoma, adenolymphoma. This Warthins tumor presented as a parotid mass in a middle-aged male, who ...
Warthin tumor (papillary cystadenoma lymphomatosum or adenolymphoma). See the list below:. * Second most common benign parotid ...
Warthin tumour (adenolymphoma, cystadenolymphoma). Three groups reflecting the changes in the karyotype of WT were ... Mark J, Dahlenfors R, Stenman G, Nordquist A. A human adenolymphoma showing the chromosomal aberrations del (7)(p12p14-15) and ...
Adenolymphoma.- 6.4. Other benign masses of the parotid gland.- 6.5. Malignant tumors.- References.- 4. Magnetic resonance ... Adenolymphoma.- 4.5. Malignant tumors.- 4.6. Miscellaneous lesions.- 5. MRI in parotid disease.- 6. Conclusions.- References.- ...
Pleomorphic adenoma and adenolymphoma in ultrasonography.. Zajkowski P, Jakubowski W, Białek EJ, Wysocki M, Osmólski A, Serafin ...
Adenolymphoma of the parotid gland, or papillary cystadenoma lymphomatosum, is better known as "Warthins tumor"; he described ...
Other serious sequelae include sialolithiasis of the submandibular gland and adenolymphoma of the parotid gland. The ...
Warthins tumor adenolymphoma.. Wilms tumor a rapidly developing malignant mixed tumor of the kidneys, made up of embryonal ...
... adenolymphoma; carcinosarcoma, chordoma, craniopharyngioma, dysgerminoma, hamartoma; mesenchymoma; mesonephroma, myosarcoma, ...
Adenolymphoma (Warthins tumour)? *Check the other side to look slick as 10 bilateral ...
Azzopardi JG, Tsün HL (1964) The genesis of adenolymphoma. J Pathol Bacteriol 88: 213-218PubMedCrossRefGoogle Scholar ... Caselitz J, Salfelder G, Seifert G (1984) Adenolymphoma: an immunohistochemical study with monoclonal antibodies against ...
Adenolymphomas: usually needed. Meningitis, myocarditis, pericarditis, pleurisy. Optic chiasm compression, eg to 4 weeks in ...
The well-circumscribed adenolymphomas of the parotid should be first considered when the male patient over 50 years old has ... To evaluate the MDCT findings of parotid adenolymphomas and to emphasize the diagnostrc value of MDCT.Methods:To analysis MDCT ... Of the 15 parotid adenolymphomas cases,12 were over fifty years old,11 were male,and 8 unilateral tumors presented.9 cases were ... performances of 15 parotid adenolymphomas patients confirmed by operational pathology retrospectively.Results: ...
... adenolymphomas (15), basal cell adenomas (2), multiple nodular acidophil adenoma (1), myoepithelioma (1) ...
... adenolymphoma, carcinosarcoma, chordoma, cranio-pharyngioma, dysgerminoma, hamartoma, mesenchymoma, mesonephroma, myosarcoma, ...
... adenolymphoma, carcinosarcoma, chordoma, craniopharyngioma, dysgerminoma, hamartoma, mesenchymoma, mesonephroma, myosarcoma, ...
Mark J, Dahlenfors R, Stenman G, Nordquist A. A human adenolymphoma showing the chromosomal aberrations del(7)(p12p14-15) and t ...
... while in fifth there was a suspicion of adenolymphoma5.Neurilemmomas in parotid region are too rare to be suspected if FNAC ...
... adenolymphoma, schwannoma, hemangioma etc. With these varieties of differentials, patients with SFTs are initially subjected ...
MeSH-minor] Adenolymphoma / diagnosis. Adenolymphoma / metabolism. Adenolymphoma / pathology. Adenoma, Pleomorphic / diagnosis ... MeSH-minor] Adenolymphoma / chemistry. Adenolymphoma / pathology. Adenoma / chemistry. Adenoma / pathology. Adenoma, ... MeSH-major] Adenolymphoma / diagnosis. Adenoma / diagnosis. Carcinoma / diagnosis. Lymphoma / diagnosis. Parotid Gland / ... MeSH-minor] Adenolymphoma / surgery. Adenoma / surgery. Adenoma, Pleomorphic / surgery. Adolescent. Adult. Aged. Humans. Middle ...
Adenolymphoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / pathology. Child. Child, ...
Monoclonal antibodies to epithelial sialomucins recognize epitopes at different cellular sites in adenolymphomas of the parotid ...
Adenolymphoma (morphologic abnormality). Code System Preferred Concept Name. Adenolymphoma (morphologic abnormality). Concept ...
Ekhtiari, H., Tavakoli, H., Addolorato, G., Baeken, C., Bonci, A., Campanella, S., Castelo-Branco, L., Challet-Bouju, G., Clark, V. P., Claus, E., Dannon, P. N., Del Felice, A., den Uyl, T., Diana, M., di Giannantonio, M., Fedota, J. R., Fitzgerald, P., Gallimberti, L., Grall-Bronnec, M., Herremans, S. C. & 56 others, Herrmann, M. J., Jamil, A., Khedr, E., Kouimtsidis, C., Kozak, K., Krupitsky, E., Lamm, C., Lechner, W. V., Madeo, G., Malmir, N., Martinotti, G., McDonald, W. M., Montemitro, C., Nakamura-Palacios, E. M., Nasehi, M., Noël, X., Nosratabadi, M., Paulus, M., Pettorruso, M., Pradhan, B., Praharaj, S. K., Rafferty, H., Sahlem, G., Salmeron, B. J., Sauvaget, A., Schluter, R. S., Sergiou, C., Shahbabaie, A., Sheffer, C., Spagnolo, P. A., Steele, V. R., Yuan, T. F., van Dongen, J. D. M., Van Waes, V., Venkatasubramanian, G., Verdejo-García, A., Verveer, I., Welsh, J. W., Wesley, M. J., Witkiewitz, K., Yavari, F., Zarrindast, M. R., Zawertailo, L., Zhang, X., Cha, Y. H., George, T. P., ...
As in most studies of black populations there were no adenolymphomas. Age distribution was bimodal with a benign peak in the ...
  • Caselitz J, Salfelder G, Seifert G (1984) Adenolymphoma: an immunohistochemical study with monoclonal antibodies against lymphocyte antigens. (springer.com)
  • Warthin's tumor, also known as papillary cystadenoma lymphomatosum or adenolymphoma , is the second most common benign tumor of the salivary glands . (omicsonline.org)