Adenocarcinoma mucinous. Medical search

A malignant epithelial tumor with a glandular organization.

An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)

Tumors or cancer of the LUNG.

Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Tumors or cancer of the ESOPHAGUS.

An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)

A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.

Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.

A carcinoma thought to be derived from epithelium of terminal bronchioles, in which the neoplastic tissue extends along the alveolar walls and grows in small masses within the alveoli. Involvement may be uniformly diffuse and massive, or nodular, or lobular. The neoplastic cells are cuboidal or columnar and form papillary structures. Mucin may be demonstrated in some of the cells and in the material in the alveoli, which also includes denuded cells. Metastases in regional lymph nodes, and in even more distant sites, are known to occur, but are infrequent. (From Stedman, 25th ed)

Tumors or cancer of the STOMACH.

That part of the STOMACH close to the opening from ESOPHAGUS into the stomach (cardiac orifice), the ESOPHAGOGASTRIC JUNCTION. The cardia is so named because of its closeness to the HEART. Cardia is characterized by the lack of acid-forming cells (GASTRIC PARIETAL CELLS).

Histochemical localization of immunoreactive substances using labeled antibodies as reagents.

Tumors or cancer of the COLON.

Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.

The area covering the terminal portion of ESOPHAGUS and the beginning of STOMACH at the cardiac orifice.

Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.

A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.

A type II keratin found associated with KERATIN-19 in ductal epithelia and gastrointestinal epithelia.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.

A cell line derived from cultured tumor cells.

A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)

Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.

Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.

Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)

Tumors or cancer of the INTESTINES.

Tumors or cancer of the PROSTATE.

Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.

Tumors or cancer of the DUODENUM.

A poorly differentiated adenocarcinoma in which the nucleus is pressed to one side by a cytoplasmic droplet of mucus. It usually arises in the gastrointestinal system.

An adenocarcinoma characterized by the presence of cells resembling the glandular cells of the ENDOMETRIUM. It is a common histological type of ovarian CARCINOMA and ENDOMETRIAL CARCINOMA. There is a high frequency of co-occurrence of this form of adenocarcinoma in both tissues.

Tumors or cancer of the CECUM.

Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.

Ability of neoplasms to infiltrate and actively destroy surrounding tissue.

An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)

A condition in which there is a change of one adult cell type to another similar adult cell type.

Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.

Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Tumors or cancer of the RECTUM.

A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.

Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.

Tumor or cancer of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.

A type I keratin expressed predominately in gastrointestinal epithelia, MERKEL CELLS, and the TASTE BUDS of the oral mucosa.

The simultaneous analysis of multiple samples of TISSUES or CELLS from BIOPSY or in vitro culture that have been arranged in an array format on slides or microchips.

Tumors or cancer in the ILEUM region of the small intestine (INTESTINE, SMALL).

A benign epithelial tumor with a glandular organization.

The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.

DNA present in neoplastic tissue.

Tumors or cancer in the JEJUNUM region of the small intestine (INTESTINE, SMALL).

The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.

The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.

Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.

A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.

A mixed adenocarcinoma and squamous cell or epidermoid carcinoma.

A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.

A malignant tumor arising from secreting cells of a racemose gland, particularly the salivary glands. Racemose (Latin racemosus, full of clusters) refers, as does acinar (Latin acinus, grape), to small saclike dilatations in various glands. Acinar cell carcinomas are usually well differentiated and account for about 13% of the cancers arising in the parotid gland. Lymph node metastasis occurs in about 16% of cases. Local recurrences and distant metastases many years after treatment are common. This tumor appears in all age groups and is most common in women. (Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1240; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575)

Experimental transplantation of neoplasms in laboratory animals for research purposes.

The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.

The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.

A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Excision of the whole (total gastrectomy) or part (subtotal gastrectomy, partial gastrectomy, gastric resection) of the stomach. (Dorland, 28th ed)

Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Tumors or cancer of the PARANASAL SINUSES.

Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.

A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.

Substances that inhibit or prevent the proliferation of NEOPLASMS.

A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)

A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.

Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.

Surgical removal of the pancreas. (Dorland, 28th ed)

Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.

Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.

Tumors or cancer of the UTERINE CERVIX.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

High molecular weight mucoproteins that protect the surface of EPITHELIAL CELLS by providing a barrier to particulate matter and microorganisms. Membrane-anchored mucins may have additional roles concerned with protein interactions at the cell surface.

Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.

Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.

Tumors or cancer of the APPENDIX.

Ducts that collect PANCREATIC JUICE from the PANCREAS and supply it to the DUODENUM.

All of the processes involved in increasing CELL NUMBER including CELL DIVISION.

The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.

Tumors or cancer of the gallbladder.

Tumors or cancer of the SIGMOID COLON.

Excision of part (partial) or all (total) of the esophagus. (Dorland, 28th ed)

Benign proliferation of the ENDOMETRIUM in the UTERUS. Endometrial hyperplasia is classified by its cytology and glandular tissue. There are simple, complex (adenomatous without atypia), and atypical hyperplasia representing also the ascending risk of becoming malignant.

A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.

Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.

Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.

A tumor of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic. (From Dorland, 27th ed)

Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.

A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.

In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.

Sialylated Lewis blood group carbohydrate antigen found in many adenocarcinomas of the digestive tract, especially pancreatic tumors.

Tumors or cancer of the UTERUS.

Tumors or cancer of the MAMMARY GLAND in animals (MAMMARY GLANDS, ANIMAL).

A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.

Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones.

One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.

An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)

The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.

Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.

An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)

An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)

The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.

Elements of limited time intervals, contributing to particular results or situations.

A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.

Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.

A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.

Tomography using x-ray transmission and a computer algorithm to reconstruct the image.

Transplantation between animals of different species.

The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.

A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.

Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

RNA present in neoplastic tissue.

A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)

Antimetabolites that are useful in cancer chemotherapy.

Endoscopic examination, therapy or surgery of the esophagus.

The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.

A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)

An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.

An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.

Removal and examination of tissue obtained through a transdermal needle inserted into the specific region, organ, or tissue being analyzed.

Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.

A pair of anal glands or sacs, located on either side of the ANUS, that produce and store a dark, foul-smelling fluid in carnivorous animals such as MEPHITIDAE and DOGS. The expelled fluid is used as a defensive repellent (in skunks) or a material to mark territory (in dogs).

A malignant cystic or semicystic neoplasm. It often occurs in the ovary and usually bilaterally. The external surface is usually covered with papillary excrescences. Microscopically, the papillary patterns are predominantly epithelial overgrowths with differentiated and undifferentiated papillary serous cystadenocarcinoma cells. Psammoma bodies may be present. The tumor generally adheres to surrounding structures and produces ascites. (From Hughes, Obstetric-Gynecologic Terminology, 1972, p185)

The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.

Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.

Antibodies produced by a single clone of cells.

Metastases in which the tissue of origin is unknown.

Inhaling and exhaling the smoke of burning TOBACCO.

A CELL CYCLE and tumor growth marker which can be readily detected using IMMUNOCYTOCHEMISTRY methods. Ki-67 is a nuclear antigen present only in the nuclei of cycling cells.

An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.

Biochemical identification of mutational changes in a nucleotide sequence.

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.

Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.

Human colonic ADENOCARCINOMA cells that are able to express differentiation features characteristic of mature intestinal cells such as the GOBLET CELLS.

Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.

A transmembrane mucin that is found in a broad variety of epithelial tissue. Mucin-4 may play a role in regulating cellular adhesion and in cell surface signaling from the ERBB-2 RECEPTOR PROTEIN-TYROSINE KINASE. Mucin-4 is a heterodimer of alpha and beta chains. The alpha and beta chains result from the proteolytic cleavage of a precursor protein.

A type of IN SITU HYBRIDIZATION in which target sequences are stained with fluorescent dye so their location and size can be determined using fluorescence microscopy. This staining is sufficiently distinct that the hybridization signal can be seen both in metaphase spreads and in interphase nuclei.

Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.

In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.

Excision of the uterus.

A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the production of an RNA transcript of the entire repeating sequence of ribosomal RNA followed by the reverse transcription of the molecule to produce an additional copy of the original DNA sequence. Laboratory techniques have been introduced for inducing disproportional replication by unequal crossing over, uptake of DNA from lysed cells, or generation of extrachromosomal sequences from rolling circle replication.

A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.

Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

An embryonic structure originating from the ALLANTOIS. It is a canal connecting the fetal URINARY BLADDER and the UMBILICUS. It is normally converted into a fibrous cord postnatally. When the canal fails to be filled and remains open (patent urachus), urine leaks through the umbilicus.

A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

Tumors or cancer of the LIVER.

Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.

Neoplasms composed of more than one type of neoplastic tissue.

A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)

Tumors or cancer of the NOSE.

Methods which attempt to express in replicable terms the level of CELL DIFFERENTIATION in neoplasms as increasing ANAPLASIA correlates with the aggressiveness of the neoplasm.

Tumors or cancer of the SALIVARY GLANDS.

The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.

The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.

A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)

Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.

Tumors or cancer of the BILE DUCTS.

A BETARETROVIRUS that causes pulmonary adenomatosis in sheep (PULMONARY ADENOMATOSIS, OVINE).

Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.

Tumors or cancer of the DIGESTIVE SYSTEM.

Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.

Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.

The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.

A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties.

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.

Tumor suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53.

A malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. (Stedman, 25th ed)

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.

A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated RECEPTOR-REGULATED SMAD PROTEINS. The complex then translocates to the CELL NUCLEUS and regulates GENETIC TRANSCRIPTION of target GENES.

Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.

Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.

Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.

Tumors or cancer of the VAGINA.

Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.

A contagious, neoplastic, pulmonary disease of sheep characterized by hyperplasia and hypertrophy of pneumocytes and epithelial cells of the lung. It is caused by JAAGSIEKTE SHEEP RETROVIRUS.

Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.

Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.

Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.

One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.

Retrograde flow of duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the STOMACH.

Increased expression of the RIalpha subunit of the cAMP-dependent protein kinase A is associated with advanced stage ovarian cancer. (1/804)

The primary element in the cAMP signal transduction pathway is the cAMP-dependent protein kinase (PKA). Expression of the RIalpha subunit of type I PKA is elevated in a variety of human tumours and cancer cell lines. The purpose of this study was to assess the prognostic importance of RIalpha expression in patients with ovarian cancer. We have evaluated the expression of RIalpha in a panel of human ovarian tumours (n = 40) and five human ovarian cancer cell lines using quantitative reverse transcription polymerase chain reaction (RT-PCR) and Western blot analysis. The human ovarian cell lines OAW42 and OTN14 express high endogenous levels of RIalpha mRNA and protein (at significantly higher mRNA levels than high tissue expressors, P < 0.05). The ovarian cell line A2780 expresses low endogenous levels of RIalpha mRNA and protein (also at higher mRNA levels than low tissue expressors, P < 0.05). Quantitative RT-PCR revealed no significant difference in RIalpha mRNA expression between different ovarian histological subtypes in this study. No associations were found between RIalpha mRNA expression and differentiation state. RIalpha mRNA expression was significantly associated with tumour stage (P = 0.0036), and this remained significant in univariate analysis (P = 0.0002). A trend emerged between RIalpha mRNA expression levels and overall survival in univariate analysis (P = 0.051), however, by multivariate analysis, stage remained the major determinant of overall survival (P = 0.0001). This study indicates that in ovarian epithelial tumours high RIalpha mRNA expression is associated with advanced stage disease. RIalpha expression may be of predictive value in ovarian cancer and may be associated with dysfunctional signalling pathways in this cancer type. (+info)

Combined inhibin and CA125 assays in the detection of ovarian cancer. (2/804)

BACKGROUND: The reproductive hormone inhibin has been used as a diagnostic marker of ovarian mucinous and granulosa cell cancers. The aims of this study were to develop a new inhibin immunofluorometric assay (alphaC IFMA) to replace an inhibin RIA as a diagnostic marker of these ovarian cancers and to assess whether the alphaC IFMA in combination with CA125, which detects serous cancers, leads to an improved biochemical diagnosis of all ovarian cancers. METHODS: Serum inhibin concentrations were determined in healthy postmenopausal women (n = 165) and women with ovarian cancers (n = 154), using an inhibin RIA and an alphaC IFMA, which detects inhibin forms containing the alphaC subunit as well as the free alphaC subunit. RESULTS: The alphaC IFMA gave a similar or better discrimination of mucinous (90% vs 71%) and granulosa cell (100% vs 100%) cancers compared with the inhibin RIA. Combination of CA125 and alphaC IFMA values by canonical variate analysis or by multiROC analysis showed that the percentage of all ovarian cancers detected was significantly increased compared with either CA125 or alphaC IFMA alone. CONCLUSIONS: The alphaC IFMA shows a similar or better specificity compared with the RIA, but with increased sensitivity. In combination with CA125, the alphaC IFMA provides an effective dual test for the detection of the majority (90%) of ovarian cancers. (+info)

Clinicopathologic characteristics of mucinous gastric adenocarcinoma. (3/804)

There has been considerable controversy over the prognosis of mucinous gastric adenocarcinoma (MGC). In this study we analyzed the clinicopathologic differences between MGC and non-mucinous gastric carcinoma (NMGC). In addition, the relationship between mucin content and other clinicopathologic variables, including prognosis in MGC, was also investigated. We reviewed 2118 patients with pathologically-confirmed gastric cancer who underwent gastrectomy at the Department of Surgery, Yonsei University College of Medicine, during the period between Jan. 1987 and Dec. 1993. Among them, 130 patients had gastric carcinoma with extracellular mucin (MGC) and 1988 patients had gastric carcinoma without extracellular mucin (NMGC). We placed the MGC patients into two groups according to mucin content: mucin content involving over 50% of the tumor (dominant type, n = 94) and mucin content involving less than 50% of the tumor area (partial type, n = 36). The results were as follows: MGC was more common in males than NMGC. The size of the tumor in MGC (mean 5.3 cm) was larger than that of NMGC (mean 4.4 cm). The patients with MGC had a higher incidence of Borrmann type IV (MGC: 16.1%, NMGC: 9.9%), more frequent serosal invasion (MGC: 75.4%, NMGC: 48.6%), lymph-node metastasis (MGC: 75.4%, NMGC: 50.7%), and peritoneal metastasis (MGC: 10.0%, NMGC: 3.5%) than patients with NMGC. The patients with MGC were more advanced in stage at the time of diagnosis and had a worse overall 10-year survival rate (44.9%) than patients with NMGC (54.7%). However, the 10-year survival rate according to the stage of MGC was similar to that of NMGC. There were no significant differences between the mucin content and other pathologic variables, including prognosis, i.e. similar biologic behavior between dominant type MGC and partial type MGC. In conclusion, we suggest that MGC was more frequently diagnosed in advanced stage than NMGC with a poorer prognosis and that it is reasonable to consider the carcinoma with mucin content involving more than 30% of the tumor area as MGC. (+info)

Tumor characteristics and clinical outcome of tubular and mucinous breast carcinomas. (4/804)

PURPOSE: To comprehensively characterize the clinical and biologic features of tubular and mucinous carcinomas in a large cohort of patients and to relate this to clinical outcome and management. PATIENTS AND METHODS: The clinical and biologic features of 444 patients with tubular and 1,221 patients with mucinous carcinomas were compared with those of 43,587 patients with infiltrating ductal carcinoma, not otherwise specified (NOS). Disease-free survival (DFS) and overall survival (OS) for patients with tubular and mucinous carcinomas were compared with those of patients with NOS carcinomas and with age-matched sets from the general population. RESULTS: Tubular and mucinous carcinomas were more likely to occur in older patients, be smaller in size (tubular only), have substantially less nodal involvement, be estrogen receptor- and progesterone receptor-positive, have a lower S-phase fraction, be diploid, and be c-erbB-2- and epidermal growth factor receptor-negative compared with NOS carcinomas. Axillary node involvement was a poor prognostic feature in mucinous but not tubular carcinomas. Mucinous carcinomas < or = 1 cm had a < or = 5% incidence of node involvement. The 5-year DFS and OS were 94% and 88% for tubular, 90% and 80% for mucinous, and 80% and 77% for NOS carcinoma, respectively (P < .001 for differences among all three types for both DFS and OS). The 5-year OS of females from the general population age-matched to the patients with tubular and mucinous carcinomas was 89% and 82%, respectively, which is not different from the OS of patients with tubular or mucinous carcinomas. CONCLUSION: The biologic phenotype of tubular and mucinous carcinomas is quite favorable. Consistent with this observation, the survival of patients with tubular and mucinous carcinomas is similar to that of the general population. Systemic adjuvant therapy and node dissection may be avoided in many patients with these special types of carcinoma. (+info)

Overexpression of H-Ryk in mouse fibroblasts confers transforming ability in vitro and in vivo: correlation with up-regulation in epithelial ovarian cancer. (5/804)

Abnormalities in the function of receptor tyrosine kinases (RTKs) have been demonstrated to be important in the pathogenesis of cancer. H-Ryk, a new member of the RTK family, is an unusual RTK in that it is catalytically inactive because of amino acid substitutions of conserved residues in the catalytic domain. We show by immunohistochemistry that it is expressed in the epithelium, stroma, and blood vessels of normal tissues. Evaluation of a panel of 33 primary ovarian tumors (2 benign, 8 borderline, and 23 malignant) was performed. H-Ryk was overexpressed in borderline and malignant ovarian tumors. In serous and clear cell subtypes, there was increased expression in the epithelium, stroma, and blood vessels. Consistent with this observation, overexpression of H-Ryk in the mouse fibroblast cell line NIH3T3 induces anchorage-independent growth and tumorigenicity in nude mice. This implies that overexpression of the receptor can be transforming and may therefore be significant in the pathogenesis of ovarian cancer. (+info)

Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast. (6/804)

The generation of vascular stroma is essential for solid tumor growth and involves stimulatory and inhibiting factors as well as stromal components that regulate functions such as cellular adhesion, migration, and gene expression. In an effort to obtain a more integrated understanding of vascular stroma formation in breast carcinoma, we examined expression of the angiogenic factor vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF); the VPF/VEGF receptors flt-1 and KDR; thrombospondin-1, which has been reported to inhibit angiogenesis; and the stromal components collagen type I, total fibronectin, ED-A+ fibronectin, versican, and decorin by mRNA in situ hybridization on frozen sections of 113 blocks of breast tissue from 68 patients including 28 sections of breast tissue without malignancy, 18 with in situ carcinomas, 56 with invasive carcinomas, and 8 with metastatic carcinomas. A characteristic expression profile emerged that was remarkably similar in invasive carcinoma, carcinoma in situ, and metastatic carcinoma, with the following characteristics: strong tumor cell expression of VPF/VEGF; strong endothelial cell expression of VPF/VEGF receptors; strong expression of thrombospondin-1 by stromal cells and occasionally by tumor cells; and strong stromal cell expression of collagen type I, total fibronectin, ED-A+ fibronectin, versican, and decorin. The formation of vascular stroma preceded invasion, raising the possibility that tumor cells invade not into normal breast stroma but rather into a richly vascular stroma that they have induced. Similarly, tumor cells at sites of metastasis appear to induce the vascular stroma in which they grow. We conclude that a distinct pattern of mRNA expression characterizes the generation of vascular stroma in breast cancer and that the formation of vascular stroma may play a role not only in growth of the primary tumor but also in invasion and metastasis. (+info)

Paradoxical correlations of cyclin-dependent kinase inhibitors p21waf1/cip1 and p27kip1 in metastatic colorectal carcinoma. (7/804)

The cyclin-dependent kinase inhibitors (CDIs) p27kip1 and p21waf1/cip1 are key cell cycle-negative regulatory enzymes. The objective of this study was to correlate expression of p27kip1 and p21waf1/cip1 with survival, chemotherapy responsiveness, and expression of the proliferation marker Ki-67 in patients with advanced colorectal cancer. Immunohistochemistry was performed with antibodies to p27kip1, p21waf1/cip1, and Ki-67 on samples from 66 patients with metastatic colorectal carcinoma. Interpretation was performed by visual inspection and automated image analysis. Patients who obtained a response to chemotherapy had greater p21waf1/cip1 tumor staining with a mean of 10.0 positive cells/high-powered field, compared with 4.5 positive cells/high-powered field for nonresponders (P = 0.03). A positive Spearman correlation was seen between Ki-67 and p27kip1 (r = 0.48; P = 0.0001), as well as between Ki-67 and p21waf1/cip1 (r = 0.48; P = 0.0001). A trend toward shorter survival was seen in patients with positive specimens (median survival of 10 months for patients with both p27kip1- and p21waf1/cip1-positive specimens, compared with 22 months for patients with neither p27kip1- nor p21waf1/cip1-positive specimens). In contrast to that previously reported in normal colonic mucosa or early-stage colorectal cancer, we observed positive correlations of Ki-67 with both p27kip1 and p21waf1/cip1, a trend toward greater CDI staining indicating worse prognosis, and greater p21waf1/cip1 staining in tumors that were chemosensitive. These findings suggest that in the metastatic setting, CDIs may show altered function, compared with their role in the normal cell cycle. (+info)

Carcinoma of the axillary breast. (8/804)

Axillary breast is one of the varieties of polymastia which is characterized by the presence of more than 2 breasts. It may cause symptoms during pregnancy, lactation, or in the premenopausal period. Unless there are obvious symptoms of lactation or the assistance of further imaging studies such as mammography and breast ultrasound, the diagnosis is often confused with subcutaneous lipoma. The incidence of axillary breast cancer is low but it should be investigated and treated properly in view of another breast cancer in the embryonic milk-line. In this paper we reviewed 4 cases of axillary breast cancer and documented some articles regarding aberrant breast and carcinoma arising from it. It is suggested that subcutaneous nodules of uncertain origin around the periphery of the breast should be viewed with suspicion and treated properly. (+info)

Mucinous adenocarcinoma [18] Squamous papilloma yes vaginal micropapillomatosis [16][17][18] Endometrioid adenocarcinoma no [18 ...

https://en.wikipedia.org/wiki/List_of_vaginal_tumors

Mucinous adenocarcinoma of the appendix tip *. Cross section of the appendix with Enterobius with H&E stain ...

https://en.wikipedia.org/wiki/Vermiform_appendix

Mucinous carcinomas must be differentiated from cervical adenocarcinoma. Mixed carcinomas are those that have both Type I and ... Some endometrioid adenocarcinomas have foci of mucinous carcinoma. The genetic mutations most commonly associated with ... Mucinous endometrial carcinomas are most often stage I and grade I, giving them a good prognosis. They typically have well- ... An MRI can be of some use in determining if the cancer has spread to the cervix or if it is an endocervical adenocarcinoma. MRI ...

https://en.wikipedia.org/wiki/Endometrial_cancer

mucinous adenocarcinoma, ICD-O 8480/3). *rak o słabej kohezji (rak o małej spoistości) i gruczolakorak z komórek sygnetowatych ... adenocarcinoma, ICD-O 8140/3) *brodawkowaty rak gruczołowy (ang. papillary adenocarcinoma, ICD-O 8260/3) ... hepatoid adenocarcinoma, ICD-O 8576/3). *gruczolakorako-rakowiak (ang. mixed adeno-neuroendocrine carcinoma, mixed ... Papillary adenocarcinoma of the stomach. „Gastric Cancer". 3 (1), s. 33-38, Aug 2000. PMID: 11984707. ...

https://pl.wikipedia.org/wiki/Rak_żołądka_człowieka

Mucinous adenocarcinoma of the urachus synchronic with colorectal adenocarcinoma. Value of immunohistochemistry in the ...

https://en.wikipedia.org/wiki/Keratin_7

Papillary mucinous tumor of low malignant potential M8480/0 Mucinous adenoma M8480/3 Mucinous adenocarcinoma Mucinous carcinoma ... M9015/3 Mucinous adenocarcinofibroma Malignant mucinous adenofibroma Mucinous cystadenocarcinofibroma Malignant mucinous ... Basophil adenocarcinoma Mucoid cell adenocarcinoma M8310/0 Clear cell adenoma M8310/3 Clear cell adenocarcinoma, NOS Clear cell ... M8140/2 Adenocarcinoma in situ, NOS (M8140/3) Adenocarcinoma, NOS M8140/6 Adenocarcinoma, metastatic, NOS M8141/3 Scirrhous ...

https://en.wikipedia.org/wiki/International_Classification_of_Diseases_for_Oncology

Aggressive digital papillary adenocarcinoma Mucinous carcinoma Skin lesion James, William D.; Berger, Timothy G.; et al. (2006 ...

https://en.wikipedia.org/wiki/Primary_cutaneous_adenoid_cystic_carcinoma

... several mucinous tumors (mucinous adenocarcinoma, mucinous cystadenoma, and mucinous cystadenocarcinoma), as well as other ... Low-grade mucinous adenocarcinoma is used by the American Joint Committee on Cancer and World Health Organization and is nearly ... The term mucinous adenocarcinoma is used in different contexts depending on the reference material used by the pathologist for ... For low-grade mucinous adenocarcinoma, disease may be designated as "benign" because tumors do not invade deeply into tissue ...

https://en.wikipedia.org/wiki/Pseudomyxoma_peritonei

... usually is an adenocarcinoma (about 90%) mostly with mucinous/colloidal histology. Other rare types include ... These findings can be precursor lesions of a primary bladder adenocarcinoma. No history of a different primary adenocarcinoma ... "Urachal Adenocarcinoma". AUAnet.org. Humphrey, Peter A.; Moch, Holger; Cubilla, Antonio L.; Ulbright, Thomas M.; Reuter, Victor ... In addition, other diagnostic systems also for urachal carcinomas that are not adenocarcinomas have been proposed. ...

https://en.wikipedia.org/wiki/Urachal_cancer

... in colonic mucinous adenocarcinoma". Glycobiology. 12 (6): 379-88. doi:10.1093/glycob/12.6.379. PMID 12107080. Akama TO, Misra ...

https://en.wikipedia.org/wiki/CHST5

This results in mucinous lung adenocarcinoma, a source of poor clinical outcomes for patients. However others have found that ... TTF1 is more than merely a clinical marker of lung adenocarcinoma. It plays an active role in sustaining lung cancer cells in ... In the thyroid, follicular and parafollicular cells are also positive for TTF-1. For lung cancers, adenocarcinomas are usually ... July 2007). "Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1". Cancer Research. 67 ...

https://en.wikipedia.org/wiki/NK2_homeobox_1

Gastric-type mucinous adenocarcinoma of the cervix is a rare type of cancer with aggressive behavior. This type of malignancy ... "A rare case of gastric-type mucinous endocervical adenocarcinoma in a 59-year-old woman". Menopausal Review. 19 (3): 147-150. ... the incidence of adenocarcinoma of the cervix has been increasing in recent decades. Endocervical adenocarcinoma represents 20- ... About 90% of cervical cancer cases are squamous cell carcinomas, 10% are adenocarcinoma, and a small number are other types. ...

https://en.wikipedia.org/wiki/Cervical_cancer

"CD133 expression pattern distinguishes intraductal papillary mucinous neoplasms from ductal adenocarcinomas of the pancreas" ( ...

https://en.wikipedia.org/wiki/CD133

NBTE may also occur in patients with cancers, particularly mucinous adenocarcinoma where Trousseau syndrome can be encountered ...

https://en.wikipedia.org/wiki/Endocarditis

... expression in human colonic non-mucinous adenocarcinoma". Jpn. J. Cancer Res. 93 (5): 507-15. doi:10.1111/j.1349-7006.2002. ...

https://en.wikipedia.org/wiki/GAL3ST2

... interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas". J ... Some adenocarcinomas secrete mucin that can interact with selectin found on platelets, thereby causing small clots to form. ... as well as adenocarcinomas of the pancreas and lung, are associated with hypercoagulability (the tendency to form blood clots) ...

https://en.wikipedia.org/wiki/Trousseau_sign_of_malignancy

She was one of the first to establish a cell line (MAC-21) from a human mucinous adenocarcinoma. Despite extensive work on this ... Cailleau, R (1960). "The Establishment of a Cell Strain (Mac-21) from a Mucoid Adenocarcinoma of the Human Lung". Cancer Res. ... MDA-MB-468 cell line was established from a pleural effusion of a 51 year old black woman with metastatic breast adenocarcinoma ... cell line that was established from a pleural effusion of a 51-year-old Caucasian female with metastatic mammary adenocarcinoma ...

https://en.wikipedia.org/wiki/Relda_Marie_Cailleau

... a form of mucinous adenocarcinoma that may be confused with microglandular hyperplasia of the cervix". Int J Gynecol Pathol. 16 ... These features however are not characteristic exclusively to MGH, often being present in adenocarcinoma-affected tissue as well ... Zaloudek C, Hayashi GM, Ryan IP, Powell CB, Miller TR (1997). "Microglandular adenocarcinoma of the endometrium: ... of Morphologic and Immunohistochemical Features of Cervical Microglandular Hyperplasia with Low-grade Mucinous Adenocarcinoma ...

https://en.wikipedia.org/wiki/Microglandular_hyperplasia

Adenosal cells can be distinguished as mucinous, tuboendometrial, and embryonic. Its mucinous cells resemble the normal ... Herbst, Arthur L.; Scully, Robert E. (1970). "Adenocarcinoma of the vagina in adolescence.A report of 7 cases including 6 clear ... Newbold, R. R.; McLachlan, J. A. (May 1982). "Vaginal adenosis and adenocarcinoma in mice exposed prenatally or neonatally to ... It is sometimes considered a precancerous lesion, given clear-cell adenocarcinoma patients present these lesions in close ...

https://en.wikipedia.org/wiki/Vaginal_adenosis

This occurs in mucinous adenocarcinoma, in which cells are poorly differentiated. If the mucus remains inside the tumor cell, ... "Moderately differentiated adenocarcinoma (colon)". pathologyatlas.ro. Archived from the original on January 26, 2016.. ... Cancer-Invasive adenocarcinoma (the most common type of colorectal cancer). The cancerous cells are seen in the center and at ... Adenocarcinoma is a malignant epithelial tumor, originating from superficial glandular epithelial cells lining the colon and ...

https://en.m.wikipedia.org/wiki/Colon_cancer

... non-mucinous bronchioloalveolar carcinoma,[29] and adenocarcinoma with mixed subtypes.[28] ... Stahel RA (July 2007). "Adenocarcinoma, a molecular perspective". Annals of Oncology. 18 (Suppl 9): ix147-9. doi:10.1093/annonc ... that EGFR-TKI's are particularly active in papillary and non-mucinous bronchioloalveolar carcinoma variants of adenocarcinoma.[ ... Motoi N, Szoke J, Riely GJ, Seshan VE, Kris MG, Rusch VW, Gerald WL, Travis WD (June 2008). "Lung adenocarcinoma: modification ...

https://en.wikipedia.org/wiki/Targeted_therapy_of_lung_cancer

Other common forms are mucinous adenocarcinoma's, adenocarcinoma-not otherwise specified (NOS), and signet ring cell ... Advanced cases for 5 year survival range from 12-28%. Mucinous cystadenoma is an obsolete term for appendiceal mucinous ... adenocarcinoma listed from highest to lowest incidence. A carcinoid is a neuroendocrine tumor (NET) of the intestines. ...

https://en.wikipedia.org/wiki/Appendix_cancer

Mucinous tumors include mucinous adenocarcinoma and mucinous cystadenocarcinoma. Mucinous adenocarcinomas make up 5-10% of ... Advanced mucinous adenocarcinomas have a poor prognosis, generally worse than serous tumors, and are often resistant to ... Low-grade serous adenocarcinomas resemble Fallopian tube epithelium, whereas high-grade serous adenocarcinomas show anaplasia ... Clear-cell adenocarcinomas are histopathologically similar to other clear cell carcinomas, with clear cells and hobnail cells. ...

https://en.wikipedia.org/wiki/Ovarian_cancer

The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ... Chiosea SI, Sherer CK, Jelic T, Dacic S (December 2011). "KRAS mutant allele-specific imbalance in lung adenocarcinoma". Modern ... "KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib". PLOS Medicine. 2 (1): e17. doi: ... "Mutant allele-specific imbalance modulates prognostic impact of KRAS mutations in colorectal adenocarcinoma and is associated ...

https://en.wikipedia.org/wiki/KRAS

... see mucinous adenocarcinoma with clinical condition Pseudomyxoma peritonei). Clear stromal invasion is used to differentiate ... As primary ovarian mucinous tumors are usually unilateral (in one ovary), the presentation of bilateral mucinous tumors ... of primary mucinous tumors are bilateral. May form very large cystic masses, with recorded weights exceeding 25 kg Mucinous ... Mucinous tumors: Closely resemble their serous counterparts but unlikely to be bilateral Somewhat less common, accounting for ...

https://en.wikipedia.org/wiki/Surface_epithelial-stromal_tumor

... mucinous carcinoma, adenoid cystic carcinoma, and ductal papillary adenocarcinoma. Benign tumors include poroma, hidradenoma, ...

https://en.wikipedia.org/wiki/Eccrine_carcinoma

Fifty percent of stage I mucinous ovarian carcinomas are associated with elevated TATI, and nearly 100% of stage IV tumors show ... Eighty-five to 95% of pancreatic adenocarcinomas are associated with increased TATI (but elevation in pancreatitis limits the ... The peptide tumor-associated trypsin inhibitor (TATI) has been used as a marker of mucinous ovarian carcinoma, urothelial ... Sixty percent of gastric adenocarcinomas show elevated TATI, in particular tumors of diffusely infiltrative/signet ring type. ...

https://en.wikipedia.org/wiki/Trypsin_inhibitor

... "miR-592 and miR-552 can distinguish between primary lung adenocarcinoma and colorectal cancer metastases in the lung". ... MicroRNA expression pattern in intraductal papillary mucinous neoplasm]". The Korean Journal of Gastroenterology = Taehan ...

https://en.wikipedia.org/wiki/Mir-552_microRNA_precursor_family

The cause of his death was determined in 2006 to have been colorectal cancer (mucinous adenocarcinoma type with mutation in the ...

https://en.wikipedia.org/wiki/Ferdinand_I_of_Naples

... particularly mucinous adenocarcinoma[2] where Trousseau syndrome can be encountered. Typically NBTE does not cause many ...

https://en.m.wikipedia.org/wiki/Endocarditis

Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ...

https://en.wikipedia.org/wiki/Gastrointestinal_carcinoid_tumor

Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ... Lung adenocarcinoma[edit]. Main article: Adenocarcinoma of the lung. Adenocarcinoma of the lung is currently the most common ... Historically, adenocarcinoma was more often seen peripherally in the lungs than small cell lung cancer and squamous cell lung ... The most common types of NSCLC are squamous cell carcinoma, large cell carcinoma, and adenocarcinoma, but there are several ...

https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma

In obstetrics and gynecology contexts, it is a form of adenomyosis that forms a mass or growth around the tissue of the inner uterus. Most cases of adenomyosis are non-symptomatic. However, it may present with dysmenorrhea and pelvic pain. In the case of juvenile cystic adenomyoma, laparoscopic enucleation results in a statistically and clinically significant reduction in dysmenorrhea, ease in any chronic pelvic pain, and low risk of recurrence.[2] ...

https://en.wikipedia.org/wiki/Adenomyoma

Lung adenocarcinoma (never-smokers) 1.7 10,200 Cause of mutations[edit]. The likely major underlying cause of mutations in ... Mucinous. *Signet ring cell carcinoma *Krukenberg tumor. *Mucinous cystadenoma / Mucinous cystadenocarcinoma *Pseudomyxoma ... Adenocarcinoma. (adeno = gland) Refers to a carcinoma featuring microscopic glandular-related tissue cytology, tissue ... Refers to a mixed tumor containing both adenocarcinoma and squamous cell carcinoma, wherein each of these cell types comprise ...

https://en.wikipedia.org/wiki/Carcinomas

... there is an increased risk of adenocarcinoma. ... Intraductal papillary mucinous neoplasm. *Mucinous cystic ...

https://en.wikipedia.org/wiki/Juvenile_polyposis_syndrome

Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ... increasing particle deposition in small airways where adenocarcinoma tends to arise.[161] The incidence of lung adenocarcinoma ... Although most cases of adenocarcinoma are associated with smoking, adenocarcinoma is also the most common form of lung cancer ... Mutations in the K-ras proto-oncogene are responsible for 10-30% of lung adenocarcinomas.[56][57] About 4% of non-small-cell ...

https://en.wikipedia.org/wiki/Lung_cancer

Adenocarcinoma in situ of the lung）（AIS），或微侵犯型肺腺癌（英语：Minimally invasive adenocarcinoma of the lung）（MIA），以及鱗屑樣為主型肺腺癌（lepidic- ... 肺腺癌（黏液性囊腺癌（英语：Mucinous cystadenocarcinoma of the lung）） ... Pulmonary adenocarcinoma: a renewed entity in 2011. Respirology. January 2012, 17 (1): 50-65. PMID 22040022. doi:10.1111/j.1440 ... Charloux A, Quoix E, Wolkove N, Small D, Pauli G, Kreisman H. The increasing incidence

https://zh.wikipedia.org/wiki/肺癌

Nagata J, Kijima H, Hasumi K, Suzuki T, Shirai T, Mine T (June 2003). "Adenocarcinoma and multiple adenomas of the large ...

https://en.wikipedia.org/wiki/Cronkhite–Canada_syndrome

Mucinous. *Signet ring cell carcinoma *Krukenberg tumor. *Mucinous cystadenoma / Mucinous cystadenocarcinoma *Pseudomyxoma ... adenocarcinomas. (8140-8429). Gastrointestinal. *tract: Linitis plastica. *Familial adenomatous polyposis. *pancreas * ...

https://en.wikipedia.org/wiki/Somatostatinoma

Adenocarcinoma. *Aggressive digital papillary adenocarcinoma. *Extramammary Paget's disease. Ungrouped. *Merkel cell carcinoma ... Mucinous carcinoma. *Primary cutaneous adenoid cystic carcinoma. *Verrucous carcinoma. *Malignant mixed tumor ...

https://en.wikipedia.org/wiki/Cutaneous_horn

粘液性囊腺瘤 / Mucinous cystadenocarcinoma（英语：Mucinous cystadenocarcinoma） *Pseudomyxoma peritonei（英语：Pseudomyxoma peritonei） ... adenocarcinoma（英语：adenocarcinoma）. (8140-8429). Gastrointestinal. *tract: 革囊胃. *Familial adenomatous polyposis（英语：Familial ... 印戒细胞癌（Signet ring cell carcinoma，SRCC），又称黏液细胞癌（mucinous cell carcinoma，MCC）是上皮组织的恶性肿瘤

https://zh.wikipedia.org/wiki/印戒细胞癌

Risk factors for pancreatic adenocarcinoma include:[2][6][11][35] *Age, sex, and ethnicity; the risk of developing pancreatic ... Pancreatic mucinous cystic neoplasms are a broad group of pancreas tumors that have varying malignant potential. They are being ... Typically, pancreatic adenocarcinoma first spreads to nearby lymph nodes, and later to the liver or to the peritoneal cavity, ... Four genes have each been found to be mutated in the majority of adenocarcinomas: KRAS (in 95% of cases), CDKN2A (also in 95 ...

https://en.wikipedia.org/wiki/Pancreatic_cancer

... or mucinous ovarian cancer.[60] Hormonal therapy in ovarian cancer survivors after surgical removal of the ovaries is generally ... decreased risk of cervical squamos cell cancer in post menopausal women treated with HRT and a weak increase in adenocarcinoma ...

https://en.m.wikipedia.org/wiki/Hormone_replacement_therapy

Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ...

https://en.wikipedia.org/wiki/Typical_pulmonary_carcinoid_tumour

... or botryoid sarcoma[1] or botryoid rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma, that can be observed in the walls of hollow, mucosa lined structures such as the nasopharynx, common bile duct, urinary bladder of infants and young children or the vagina in females, typically younger than age 8. The name comes from the gross appearance of "grape bunches" (botryoid in Greek). ...

https://en.wikipedia.org/wiki/Sarcoma_botryoides

... adenocarcinoma）發源於胰臟製造消化酶的部位[6]；該部位也可能發生其他幾種通稱為非腺癌（non-adenocarcinomas）的癌症[6]。另外1－2%的病例為來自神經內分泌細胞的神經內分泌腫瘤[6]，這類癌症的侵襲性通常沒有胰臟腺癌強[ ... 最後一種則是主要發生在女性的胰黏液

https://zh.wikipedia.org/zh-tw/胰臟癌

Leow CC, Polakis P, Gao WQ (Nov 2005). "A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma". Annals of the ... Park ET, Oh HK, Gum JR, Crawley SC, Kakar S, Engel J, Leow CC, Gao WQ, Kim YS (Sep 2006). "HATH1 expression in mucinous cancers ...

https://ar.wikipedia.org/wiki/ATOH1

Aggressive digital papillary adenocarcinoma. *Apocrine gland carcinoma. *Ceruminoma. *Cutaneous myoepithelioma. *Cylindroma. * ...

https://en.m.wikipedia.org/wiki/Sweat_gland

... s are tumours that arise from granulosa cells. They are esterogen secreting tumors and present as large, complex, ovarian masses. These tumours are part of the sex cord-gonadal stromal tumour or non-epithelial group of tumours. Although granulosa cells normally occur only in the ovary, granulosa cell tumours occur in both ovaries and testicles (see Ovarian cancer and Testicular cancer). These tumours should be considered malignant and treated in the same way as other malignant tumours of ovary. The ovarian disease has two forms, juvenile and adult, both characterized by indolent growth,[1] and therefore has high recovery rates.[2][3] The staging system for these tumours is the same as for epithelial tumours and most present as stage I.[4] The peak age at which they occur is 50-55 years, but they may occur at any age. Juvenile granulosa cell tumour is a similar but distinct rare tumour. It too occurs in both the ovary and testis. In the testis it is extremely rare, and has ...

https://en.wikipedia.org/wiki/Granulosa_cell_tumour

Histologically, sewòm adenocarcinomas gen psammoma kò yo. Ba-klas sewòm adenocarcinomas sanble ak Fallopian rive jouk nan vant ... Fimen tabak se ki asosye avèk yon pi gwo risk nan mucinous kansè nan ovè; apre sispann fimen, risk la evantyèlman retounen nan ... Krukenberg timè gen non sou chak pyè ring selil yo ak mucinous selil yo. kansè nan Andometryo ak lymphomas kapab tou ... epilelyom, lè nou konsidere ke-wo klas sewòm adenocarcinomas montre anaplasia ak nikleyè atypia. ...

https://ht.wikipedia.org/wiki/Kansè_nan_ovè_a

... mucinous adenocarcinoma (MAC) of appendix, mesothelioma, low-grade sarcoma. Ovarian Cancer[edit]. Among patients with stage III ...

https://en.wikipedia.org/wiki/Intraperitoneal_hyperthermic_chemoperfusion

Adenocarcinoma (Mucinous cystadenocarcinoma). *Large-cell lung carcinoma. *Rhabdoid carcinoma. *Sarcomatoid carcinoma. * ... generally representing adenocarcinomas) generally doubles in volume over 3 to 5 years.[7] One volume doubling equals ...

https://en.wikipedia.org/wiki/Lung_nodule

Mucinous cystadenocarcinoma Brenner tumor Granulosa cell tumor Krukenberg tumor Society and culture[edit]. Cryopreservation[ ...

https://en.wikipedia.org/wiki/Ovary

exocrine pancreas: Adenocarcinoma. *Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal ...

https://en.wikipedia.org/wiki/Digestive_system_neoplasm

... Akiko Matsuzaki,1,2 Masanao Saio,1,2 Noritake Kosuge,1,2 Hajime ... Primary villoglandular mucinous adenocarcinoma of the vulva is rare tumor. We report a case of 68-year-old woman who developed ...

https://www.hindawi.com/journals/cripa/2017/1765460/abs/

Gastric biopsy : Mucinous adenocarcinoma grade2/3. Peritoneal biopsy: Metastatic mucinous adenocarcinoma. Gastric cancer, ... Mucinous adenocarcinomas of the stomach and colon can demonstrate a sand-like calcific pattern. Larger more discrete focal ... and defines mucinous gastric carcinoma as "an adenocarcinoma in which a substantial amount of extracellular mucin (more than 50 ... Diagnosed as esophageal adenocarcinoma outside for evaluation.. A CT scan of chest with IV contrast and CT of the abdomen and ...

https://www.diagnosticimaging.com/view/mucinous-adenocarcinoma-stomach

... Kazuo Inui, Junji ... In 6 of the 141 patients observed for intraductal papillary mucinous neoplasm (4.2%), pancreatic ductal adenocarcinoma ... while type IV suggested intraductal papillary mucinous adenocarcinoma (IPMC). We recommended surgical treatment for patients ... a Japanese multiinstitutional study of intraductal papillary mucinous tumor and mucinous cystic tumor," Pancreas, vol. 28, no. ...

https://www.hindawi.com/journals/isrn/2011/940378/

External Validation of the Simplified Preoperative Assessment for Low-Grade Mucinous Adenocarcinoma of the Appendix.. Milovanov ... Comment on: External Validation of the Simplified Preoperative Assessment for Low-Grade Mucinous Adenocarcinoma of the Appendix ... in low-grade mucinous adenocarcinoma (LGMA) of the appendix, based on preoperative CT scans. This study independently evaluates ...

https://www.ncbi.nlm.nih.gov/pubmed/28315061

Primary pulmonary mucinous adenocarcinoma (PPMA) is an uncommon subtype of lung adenocarcinoma. The present study attempted to ... The majority of mucinous adenocarcinomas expressed thyroid transcription factor 1, Napsin A, Villin and Cam5.2 proteins. KRAS ... Diagnosis, clinicopathological characteristics and prognosis of pulmonary mucinous adenocarcinoma. *Authors: *Fei Sun ... of patients and were more prevalent in the lower lung lobe and in patients with invasive mucinous adenocarcinoma. A total of 2 ...

https://www.spandidos-publications.com/ol/15/1/489/abstract

The authors present the case of a 68-year-old male with mucinous adenocarcinoma of the ileal neobladder. The adenocarcinoma ... Mucinous Adenocarcinoma of the Ileal Neobladder 20 Years After Cystectomy: The First Reported Case .utlogo1 { display: none ! ... He developed mucinous adenocarcinoma with villous adenoma in the ileal pouch 20 years later. This appears to be the first ... However, the present authors did not find any previous report of mucinous adenocarcinoma arising in an ileal pouch after ...

https://www.urotoday.com/volume-2-2009/vol-2-issue-6/33120-mucinous-adenocarcinoma-of-the-ileal-neobladder-20-years-after-cystectomy-the-first-reported-case-2226036.html

There is no association between undergoing chemotherapy and OS in this cohort of patients with stage IV low-grade mucinous ... appendiceal adenocarcinoma. Development of national treatment guidelines is urgently needed for more consistency in the ... Systemic chemotherapy and survival in patients with metastatic low-grade appendiceal mucinous adenocarcinoma J Surg Oncol. 2019 ... between undergoing chemotherapy and OS in this cohort of patients with stage IV low-grade mucinous appendiceal adenocarcinoma. ...

https://pubmed.ncbi.nlm.nih.gov/31236958/

... discusses findings from an Italian multicenter cohort of patients with invasive mucinous adenocarcinoma, a rare histotype of ... Trombetta on Recurrent NRG1 Rearrangements in Invasive Mucinous Adenocarcinoma. April 6, 2019 ... discusses findings from an Italian multicenter cohort of patients with invasive mucinous adenocarcinoma, a rare histotype of ... discusses findings from an Italian multicenter cohort of patients with invasive mucinous adenocarcinoma (IMA), a rare histotype ...

https://www.onclive.com/view/dr-trombetta-on-recurrent-nrg1-rearrangements-in-invasive-mucinous-adenocarcinoma

Impact of Mucinous Histology on the Prognosis of Stage I-III Adenocarcinomas of the Appendix: a Population-Based, Propensity ... In an unadjusted analysis, the 5-year OS and CSS in patients with a mucinous adenocarcinoma (MC) was 76.8 % (95 % confidence ... Whereas the poor prognosis of signet ring cell adenocarcinomas of the appendix is well known, the significance of mucinous ... Appendix cancer; Mucinous adenocarcinoma; Propensity score; SEER; Surveillance, Epidemiology, and End Results Program ...

https://www.ncbi.nlm.nih.gov/pubmed/27120448

Trousseau syndrome often occurs with mucinous adenocarcinomas, which secrete abnormally glycosylated mucins and mucin fragments ... interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas. ... interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas. ...

https://www.jci.org/articles/view/18882/figure/1

There are 2 clinical trials for endometrial mucinous adenocarcinoma, of which 2 are open and 0 are completed or closed. Of the ... ER and PR are the most frequent gene inclusion criteria for endometrial mucinous adenocarcinoma clinical trials [3]. ... Abemaciclib, atezolizumab, and bevacizumab are the most common interventions in endometrial mucinous adenocarcinoma clinical ... endometrial mucinous adenocarcinoma as an inclusion criterion, 2 are phase 2 (2 open). ...

https://www.mycancergenome.org/content/disease/endometrial-mucinous-adenocarcinoma/

For the mucinous carcinomas involving the remainder of the colon, please refer to the article on mucino... ... Mucinous adenocarcinomas of the appendix are on the malignant end of the spectrum of the mucinous neoplasms that affect the ... Mucinous adenocarcinomas of the appendix are on the malignant end of the spectrum of the mucinous neoplasms that affect the ... An adenocarcinoma is defined as mucinous when extracellular mucin corresponds to more than 50% of the lesion. The signet ring ...

https://radiopaedia.org/articles/mucinous-adenocarcinoma-of-the-appendix-1

... consisting of both villous adenoma and mucinous adenocarcinoma of the urachus. The tumor was incidentally discovered during ... Mucinous adenocarcinoma of the urinary bladderJournal of UrologyYear: 19551196871. 3. Herr HW. Urachal carcinoma: the case for ... A Giant Mucinous Adenocarcinoma Arising within a Villous Adenoma of the Urachus: Case Report and Review of the Literature ... Mucinous papillary adenocarcinoma of the bladder arising within villous adenoma of urachal remnants. An Immunohistochemical and ...

http://www.biomedsearch.com/nih/Giant-Mucinous-Adenocarcinoma-Arising-within/20182635.html

Inicio Cirugía Española (English Edition) Obstructive Jaundice Caused by a Mucinous Adenocarcinoma of the Appendix in a Pa... ... The intraoperative sample identified the mass as a mucinous adenocarcinoma, and we therefore decided to carry out total ... Obstructive Jaundice Caused by a Mucinous Adenocarcinoma of the Appendix in a Patient With Intestinal Malrotation ... One type is appendiceal mucocele, which leads to dilatation of the appendiceal lumen caused by mucinous material in its ...

https://www.elsevier.es/en-revista-cirugia-espanola-english-edition--436-articulo-obstructive-jaundice-caused-by-mucinous-S2173507714000647

Complete Response of Advanced Invasive Mucinous Adenocarcinoma of the Lung with Gemcitabine and PemetrexedComplete Response of ... Advanced Invasive Mucinous Adenocarcinoma of the Lung with Gemcitabine and PemetrexedAN00120815. ...

http://jairo.nii.ac.jp/0028/00018763/en

... colonic type adenocarcinoma, mucinous adenocarcinoma, signet ring type adenocarcinoma and others. In a group of 1095 patients ... Primary Mucinous Adenocarcinoma of the Vermiform Appendix with High Grade Microsatellite Instability Moritz Komm1 , Michaela ... 5. Kabbani W, Houlihan PS, Luthra R, Hamilton SR, Rashid A. Mucinous and nonmucinous appendiceal adenocarcinomas: different ... Komm M, Kronawitter-Fesl M, Kremer M, Lutz L, Holinski-Feder E, Kopp R. Primary Mucinous Adenocarcinoma of the Vermiform ...

https://jcancer.org/v02p0302.htm

Mucinous adenocarcinoma (MC) is a special histology subtype of colorectal adenocarcinoma. The survival of MC is controversial ... Prognostic significance and molecular features of colorectal mucinous adenocarcinomas: A strobe-compliant study. Wang, Mo-Jin ... MC was more frequently localized in the right colon compared with nonmucinous adenocarcinoma (NMC) in both SEER (57.7% vs 37.2 ...

http://oru.diva-portal.org/smash/record.jsf?pid=diva2:909019

We present 47 cases (1991 to 2006) of mucinous carcinomas treated by radical prostatectomy. Mean patient age at diagnosis was ... Mucinous adenocarcinoma of the prostate is one of the least common variants of prostate cancer. The prognosis of this variant ... Prognosis of Mucinous Adenocarcinoma of the Prostate Treated by Radical Prostatectomy: A Study of 47 Cases ... Mucinous adenocarcinoma of the prostate is one of the least common variants of prostate cancer. The prognosis of this variant ...

https://insights.ovid.com/crossref?an=00000478-200803000-00016

Coexistence of appendix mucinous cystadenoma, tubulovillous adenoma of the colon and adenocarcinoma of the colon. Albayrak Y. 1 ...

https://www.minervamedica.it/en/journals/minerva-chirurgica/article.php?cod=R06Y2012N03A0284

Perianal Paget disease secondary to pagetoid spread of mucinous adenocarcinoma of the anal canal Volume 28, issue 2, March- ... Perianal Paget disease secondary to pagetoid spread of mucinous adenocarcinoma of the anal canal ...

http://www.jle.com/en/revues/ejd/e-docs/perianal_paget_disease_secondary_to_pagetoid_spread_of_mucinous_adenocarcinoma_of_the_anal_canal_311312/article.phtml

... premalignant precursors of pancreatic adenocarcinomas. by Logan Thomison , Apr 25, 2016 , 0 comments ... Intraductal papillary mucinous neoplasms (IPMNs) are premalignant pancreatic cysts of which a subset has the potential to ... Immunobiology and immunosurveillance in patients with intraductal papillary mucinous neoplasms (IPMNs), ...

https://www.physiciansweekly.com/immunobiology-and-immunosurveillance-in-patients-with-intraductal-papillary-mucinous-neoplasms-ipmns-premalignant-precursors-of-pancreatic-adenocarcinomas/

Human-Stomach poor differentiated mucinous adenocarcinoma, partly signet-ring cell carcinoma tissue section slide (paraffin ... Home » Tissue Slides » Human-Stomach poor differentiated mucinous adenocarcinoma, partly signet-ring cell carcinoma tissue ... S0461 Human-Stomach poor differentiated mucinous adenocarcinoma, partly signet-ring cell carcinoma tissue section slide ( ... Properties for Human-Stomach poor differentiated mucinous adenocarcinoma, partly signet-ring cell carcinoma tissue section ...

https://www.acris-antibodies.com/tissue-slides/human-stomach-poor-differentiated-mucinous-adenocarcinoma-partly-signet-ring-cell-carcinoma-tissue-section-slide-paraffin-embedded-s0461.htm

Mucinous colorectal adenocarcinoma: clinical pathology and treatment options. Overview of attention for article published in ...

https://www.altmetric.com/details/71975875

... "mucinous adenocarcinoma", and "perianal mucinous adenocarcinoma". Among 50 journal articles, we chose 33 studies describing the ... in which seven of them showed the origin of mucinous anal adenocarcinoma from chronic peri-anal fistula. The existence of a ... and association between mucinous anal adenocarcinoma and chronic peri-anal fistula. After quality assessment, eight case ... A peri-anal adenocarcinoma is an abnormal growth of cells in the anal rectal area. Establishing the relationship between the ...

https://www.cureus.com/articles/34837-an-association-of-mucinous-adenocarcinoma-with-chronic-peri-anal-fistula-a-brief-review-of-pathophysiology-of-rare-tumor

Vitamin A contents of rat intestinal epithelium and jejunal mucinous adenocarcinoma. , Journal of the National Cancer Institute ... Vitamin A contents of rat intestinal epithelium and jejunal mucinous adenocarcinoma. P R Sundaresan L M De Luca 6/1/1977 ... Vitamin A contents of rat intestinal epithelium and jejunal mucinous adenocarcinoma. J Natl Cancer Inst. 1977;58(6):1643-5. ... The concentration of vitamin A per cell in the adenocarcinoma tissue was about 20 times less than that in intestinal epithelium ...

https://www.docphin.com/research/article-detail/16042175/PubMedID-194041/Vitamin-A-contents-of-rat-intestinal-epithelium-and-jejunal-mucinous-adenocarcinoma

Adenocarcinoma mucinous, T, N, M = T3, N0, M0, Grade: G2, Stage: IIA, Lymph Node Metastases: no, Distant Metastasis: no, Tumour ... Adenocarcinoma mucinous, T, N, M = T3, N0, M0, Grade: G2, Stage: IIA, Lymph Node Metastases: no, Distant Metastasis: no, Tumour ...

https://www.talk-bio.com/product-page/adenocarcinoma-mucinous-42

Adenocarcinoma mucinous, T, N, M = T3c, Nx, M1b, Grade: G2, Stage: IVB, Lymph Node Metastases: no, Distant Metastasis: yes, ... Adenocarcinoma mucinous, T, N, M = T3c, Nx, M1b, Grade: G2, Stage: IVB, Lymph Node Metastases: no, Distant Metastasis: yes, ...

https://www.talk-bio.com/product-page/adenocarcinoma-mucinous-4

Mucinous" by people in this website by year, and whether "Adenocarcinoma, Mucinous" was a major or minor topic of these ... "Adenocarcinoma, Mucinous" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Adenocarcinoma, Mucinous" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Adenocarcinoma, Mucinous". ...

https://profiles.wakehealth.edu/display/92336

Bladder metastases of appendiceal mucinous adenocarcinoma: A case presentation. Gianluigi Taverna, Matteo Corinti, Piergiuseppe ... Bladder metastases of appendiceal mucinous adenocarcinoma : A case presentation. / Taverna, Gianluigi; Corinti, Matteo; Colombo ... Fingerprint Dive into the research topics of Bladder metastases of appendiceal mucinous adenocarcinoma: A case presentation. ... Bladder metastases of appendiceal mucinous adenocarcinoma : A case presentation. In: BMC Cancer. 2010 ; Vol. 10. ...

https://moh-it.pure.elsevier.com/en/publications/bladder-metastases-of-appendiceal-mucinous-adenocarcinoma-a-case-

The patients were stratified into three groups according to their histological type: mucinous carcinoma (MC), signet ring cell ... We report the clinicopathological features and prognosis of patients with mucinous histology who underwent radical-intent ... The clinicopathological characteristics and outcomes of mucinous gastric adenocarcinoma (GC) remain unclear. ... Clinicopathological characteristics and outcomes in stage I-III mucinous gastric adenocarcinoma: a retrospective study at a ...

https://wjso.biomedcentral.com/articles/10.1186/s12957-016-0886-5

The World Health Organization classifies gastric carcinoma into four types-(a) papillary, (b) tubular, (c) mucinous, and (d) signet ring cell - and defines mucinous gastric carcinoma as "an adenocarcinoma in which a substantial amount of extracellular mucin (more than 50 percent of the tumor) is retained within the tumor. (diagnosticimaging.com)
MD Anderson Cancer Center developed a computed tomography (CT)-based preoperative assessment tool simplified preoperative assessment for appendix tumor (SPAAT) for predicting incomplete cytoreduction (IC) in low-grade mucinous adenocarcinoma (LGMA) of the appendix, based on preoperative CT scans. (nih.gov)
We present an exceptional case of a giant urachal tumor, consisting of both villous adenoma and mucinous adenocarcinoma of the urachus. (biomedsearch.com)
Histological investigation of the appendectomy specimen showed a mucinous adenocarcinoma and the patient was treated by secondary right hemicolectomy giving the final histopathological classification of an UICC IIIC tumor. (jcancer.org)
The mucinous lakes constitute more than 50% of the tumor mass which is a criterion for the mucinous type of the appendiceal carcinoma. (jcancer.org)
All together, taking into account both the mucinous and nonmucinous tumor, 20/47 cases (42.5%) had EEPE and 6/47 (12.7%) had positive margins. (ovid.com)
Therefore, we suggest that PAUF may be a practical biomarker for histopathological categorization and a prognostic marker for patients with an ovarian mucinous tumor. (elsevier.com)
The goal of our study was to provide comprehensive data on the worldwide human papillomavirus (HPV) genotype distribution in patients with invasive cervical adenocarcinoma in correlation with histologic tumor subtypes, geographical location, patients' age, and duration of sample storage. (nature.com)
HPV testing and vaccination will not provide full coverage for a very small subset of classical adenocarcinomas and most of the rare tumor variants such as clear cell, serous, endometrioid, and minimal deviation. (nature.com)
Mucinous colorectal adenocarcinoma is a distinct subtype of colorectal cancer (CRC) characterized by the presence of abundant extracellular mucin which accounts for at least 50% of the tumor volume. (biomedcentral.com)
The most common histologic subtype of CRC is adenocarcinoma, of which mucinous adenocarcinoma is a distinct subtype and is characterized by abundant mucinous components that comprise of at least 50% of the tumor volume [ 2 ]. (biomedcentral.com)
Colorectal Mucinous Cancers Are a Distinct Genetic Subtype (http://www.medscape.com/viewarticle/559247) Jul 3, 2007 The characteristics of colorectal mucinous carcinoma have not yet been fully clarified, due to the relatively low incidence of this type of tumor. (herbalous.com)
Colon tumor - Mucinous (colloid) carcinoma of colon (http://www.pathologyoutlines.com/topic/colontumorco lloid.html) May 25, 2012 Colon tumor. (herbalous.com)
Just found out Tues my dad has stage IV colon cancer w/ liver met.Mucinous Adenocarcinoma is the type he has.Went Thurs to get port.Starts Chemo next week.He was having abdominal pain and vomiting.Surgeon went in for exploratory surgery to remove obstruction.Found large tumor on colon, removed and reconnected also found small tumor on liver removed.I just dont know whats next or what to expect. (cancer.org)
Microscopically, the tumor consisted primarily of an endometrioid adenocarcinoma of usual type which focally showed endocervical-type mucinous differentiation (Figure 1 A). Endocervical-type mucinous differentiation is characterized by tall columnar mucin filled cells with basally located nuclei. (biomedcentral.com)
Two adjacent microscopic foci also showed readily visible intestinal-type mucinous differentiation with basally located hyperchromatic nuclei and goblet cells (Figure 1 B). There was involvement of superficial adenomyosis by tumor, but no true myometrial invasion. (biomedcentral.com)
50% of the relatively rare intraductal papillary mucinous tumor (IPMT), which arises in the main pancreatic ducts. (elsevier.com)
After excluding the possibility of an extra-gynecologic tract primary through extensive clinical investigations and post-surgical follow-up, we concluded that this tumor most likely represented a mucinous adenocarcinoma of tubal origin. (hofstra.edu)
Intraductal papillary mucinous tumor (IPMT) was diagnosed under the characteristic imaging findings. (isciii.es)
The permanent pathological picture showed mucinous adenocarcinoma characterized by dysplastic tumor nests with nuclear pleomorphism, increased nucleus-to-cytoplasm (N/C) ratio, and hyperchromatism ( Fig. 1B ). (isciii.es)
Mucinous cystadenoma is a benign cystic tumor lined by a mucinous epithelium. (wikipedia.org)
Even though mucinous cystadenoma are common ovarian tumor, what makes PRMC so rare is their retroperitoneal location. (wikipedia.org)

Asymptomatic patients with intraductal papillary mucinous neoplasms (IPMN) of the pancreas are common in Japan, as these tumors are detected by widely conducted ultrasonographic mass surveys. (hindawi.com)
Urachal adenocarcinoma is extremely uncommon and accounts for 0.11%?0.34% of all bladder tumors. (biomedsearch.com)
Pancreatic adenocarcinoma up-regulated factor (PAUF) expression is elevated in both ovarian tumors and pancreatic adenocarcinoma. (elsevier.com)
In this study, we examined various clinicopathologic features of 24 patients with mucinous cystadenoma (MCA), 36 with mucinous borderline tumors (MBTs), and 46 with mucinous adenocarcinomas (MACs) according to PAUF expression status assessed using immunohistochemistry. (elsevier.com)
Three HPV genotypes, HPV 16, 18, and 45, dominated in all adenocarcinomas and together accounted for 94.1% of HPV-positive tumors. (nature.com)
Mucinous CRC has some distinct genomic aberrations when compared with non-mucinous adenocarcinoma, many of which are driven by the increased frequency of MSI-H tumors. (cdc.gov)
In this report, we present the case of a patient affected by appendiceal cystadenoma, a colorectal adenocarcinoma, and a concomitant bladder carcinoma, as well as the results of the molecular study of the most relevant mutational pathways involved in these tumors. (uniss.it)
Welcome to Digital Library Tata Memorial Hospital catalog › Details for: Value of delayed PET imaging in mucinous adenocarcinoma rectum: should this be employed while evaluating mucinous tumors with FDG-PET? (tmc.gov.in)
Value of delayed PET imaging in mucinous adenocarcinoma rectum: should this be employed while evaluating mucinous tumors with FDG-PET? (tmc.gov.in)
Mucinous adenocarcinoma of the fallopian tube is exceptionally rare and the detailed clinicopathologic features of these tumors have not yet been reported in English literature. (hofstra.edu)
Mucinous cystadenomas may be found in the: Ovary-ovarian mucinous cystadenoma Pancreas-pancreatic mucinous cystadenoma Peritoneum-peritoneal mucinous cystadenoma Liver-mucinous cystadenoma of the liver Vermiform appendix-appendiceal mucinous cystadenoma (see cystadenoma) Mucinous cystadenomas make up 15-20% of all ovarian tumors. (wikipedia.org)
Benign mucinous cystadenomas compose 80% of mucinous ovarian tumors and 20-25% of benign ovarian tumors overall. (wikipedia.org)
On an average, mucinous accounts for 40%-50% of cystic tumors, and serous cytadenoma accounts for 30% of it. (wikipedia.org)

abstract = "Background: Appendiceal adenocarcinoma is rare with a frequency of 0.08% of all surgically removed appendices. (elsevier.com)
abstract = "Mucinous differentiation of endocervical type has been well documented in endometrial carcinoma. (elsevier.com)
Authors: Tian X, Gao S, Liu Y, Xuan Y, Wu R, Zhang Z Abstract Adenocarcinoma is one of the most common pathological types of human lung cancer and has the highest incidence and mortality rates worldwide. (medworm.com)

External Validation of the Simplified Preoperative Assessment for Low-Grade Mucinous Adenocarcinoma of the Appendix. (nih.gov)
Impact of Mucinous Histology on the Prognosis of Stage I-III Adenocarcinomas of the Appendix: a Population-Based, Propensity Score-Matched Analysis. (nih.gov)
Whereas the poor prognosis of signet ring cell adenocarcinomas of the appendix is well known, the significance of mucinous histology remains unclear. (nih.gov)
Patients with stage I-III adenocarcinoma of the appendix who underwent surgery between 2004 and 2012 were identified in the Surveillance, Epidemiology, and End Results database. (nih.gov)
Overall, 980 patients with appendix cancer were included, of which 449 (45.8 %) had a mucinous histology. (nih.gov)
Mucinous adenocarcinomas of the appendix are on the malignant end of the spectrum of the mucinous neoplasms that affect the caecal appendix . (radiopaedia.org)
Considerable controversy still exists on mucinous neoplasms of the appendix pathologic classification and nomenclature 1 . (radiopaedia.org)
Mucinous neoplasms of the appendix: a current comprehensive clinicopathologic and imaging review. (radiopaedia.org)
Komm M, Kronawitter-Fesl M, Kremer M, Lutz L, Holinski-Feder E, Kopp R. Primary Mucinous Adenocarcinoma of the Vermiform Appendix with High Grade Microsatellite Instability. (jcancer.org)
Primary adenocarcinoma of the vermiform appendix is a rare entity and is frequently discovered by the pathologist following appendectomy for suspected appendicitis. (jcancer.org)
We present a 42-year-old male with primary mucinous adenocarcinoma of the appendix initially presenting symptoms of acute appendicitis. (jcancer.org)
Neoplasms of the appendix are found in 1% of all appendectomy specimen with a frequency of appendiceal adenocarcinoma in 0,1% of the specimen investigated. (jcancer.org)
The histopathological examination of the specimen surprisingly revealed a pT4a (local infiltration of the visceral peritoneum) mucinous adenocarcinoma of the appendix (figure 1 ) with positive resection margins (R1 resection). (jcancer.org)
Few cases of appendiceal carcinoma infiltrating the bladder wall for spatial contiguity have been documented.Case Presentation: A case is reported of a 45-years old woman with mucinous cystadenocarcinoma of the appendix with bladder metastasis. (elsevier.com)
The subsequent pathological examination revealed a mucinous cystadenocarcinoma of the appendix with metastatic cells colonising the anterior bladder wall and several colic lymph nodes.Conclusions: The rarity of the appendiceal carcinoma invading the urinary bladder and its usual involvement of nearest organs and the posterior bladder wall, led us to describe this case which demonstrates the ability of the appendiceal cancer to metastasize different regions of urinary bladder. (elsevier.com)
mucinous adenocarcinoma ( colon /appendix) - need help to understand (http://www.cancerforums.net/threads/16345-mucinous- adenocarcinoma-(colon-appendix)-need-help-to-unders tand) Hi There, I'm trying desperately to find information about mucinous adenocarcinoma that I can easily digest. (herbalous.com)
The next most common type of cancer of the appendix is an adenocarcinoma. (rarediseases.org)
Diseases associated with PAN3 include Appendix Adenocarcinoma . (genecards.org)

We retrospectively investigated the incidence of pancreatic ductal adenocarcinoma among patients with intraductal papillary mucinous neoplasms of the pancreas. (hindawi.com)
Serial observation of patients with intraductal papillary mucinous neoplasms by contrast-enhanced computed tomography or magnetic resonance cholangiopancreatography therefore is critical, whether or not surgical treatment initially was performed. (hindawi.com)
According to a panel of specialist review in 2016, a new nomenclature and classification for the appendiceal mucinous neoplasms based on their histologic type and biologic behaviour has been proposed and since then the term mucinous adenocarcinoma should be reserved for the mucinous tumours that have an infiltrative invasion beyond the muscularis mucosa 1,2 . (radiopaedia.org)
Staging and management of these are different from those of colorectal carcinoma , please refer to the appendiceal mucinous neoplasms TNM staging for further details. (radiopaedia.org)
Immunobiology and immunosurveillance in patients with intraductal papillary mucinous neoplasms (IPMNs), premalignant precursors of pancreatic adenocarcinomas. (physiciansweekly.com)
Intraductal papillary mucinous neoplasms (IPMNs) are premalignant pancreatic cysts of which a subset has the potential to progress to cancer. (physiciansweekly.com)
Mucinous adenocarcinoma of the renal pelvis may be classified as among the rarest neoplasms of the genitourinary tract. (isciii.es)

Kamata T, Yoshida A, Shiraishi K, Furuta K, Kosuge T, Watanabe S, Asamura H and Tsuta K: Mucinous micropapillary pattern in lung adenocarcinomas: A unique histology with genetic correlates. (spandidos-publications.com)
The aim of this population-based study was to evaluate if mucinous histology is an independent prognostic factor in appendiceal adenocarcinomas. (nih.gov)
The present population-based, propensity score matched analysis shows that mucinous histology does not affect survival in stage I-III appendiceal adenocarcinoma patients. (nih.gov)
Mucinous adenocarcinoma (MC) is a special histology subtype of colorectal adenocarcinoma. (diva-portal.org)
We report the clinicopathological features and prognosis of patients with mucinous histology who underwent radical-intent gastrectomy. (biomedcentral.com)
The guidelines established by the National Comprehensive Cancer Network do not describe mucinous histology as a clinical factor that should influence the therapeutic algorithm. (biomedcentral.com)
A multivariate analysis for overall survival revealed a mucinous histology to be an independent prognostic factor. (biomedcentral.com)
In StageIII, local recurrence in rectal cases and peritoneal dissemination were more frequently observed in patients with a mucinous histology. (biomedcentral.com)
In rectal StageIII disease with mucinous histology, additional therapy to control local recurrence followed by surgical resection may be a strategical alternative. (biomedcentral.com)
Compared with non-MAC, MAC patients had more T2 patients and more MSI phenotypes in stage I CRC at presentation, but the mucinous histology is not a significant predictor of recurrence and prognosis in stage I CRC. (researchsquare.com)
However, considering their impaired response to current chemotherapies, treatments specialized for patients with mucinous colorectal adenocarcinoma histology are urgently needed. (biomedcentral.com)
The presence of a carcinoma of mucinous histology occurring synchronously in the perianal region and the colon is exceptionally rare. (duhnnae.com)
Histology showed an adenocarcinoma with a clear resection margins. (duhnnae.com)

The prognostic value of the mucinous adenocarcinoma histotype on the early stages especially for stage I colorectal cancer (CRC) is still unclear. (researchsquare.com)
Multivariate analysis was performed to determine whether mucinous histotype itself was an independent prognostic impact in stage I patients. (researchsquare.com)
Prognostic Impact of Cell Division Cycle Associated 2 Expression on Pancreatic Ductal Adenocarcinoma [J]. Chinese Medical Sciences Journal, 2016, 31(3): 149-154. (cams.cn)
However, the factors involved in the development of the mucinous colorectal adenocarcinoma and their prognostic implications are not yet well understood. (biomedcentral.com)
TOX3 is a favorable prognostic indicator and potential immunomodulatory factor in lung adenocarcinoma. (medworm.com)

KRAS mutations were observed in 62% of patients and were more prevalent in the lower lung lobe and in patients with invasive mucinous adenocarcinoma. (spandidos-publications.com)
Pathologic evaluation revealed a muscle-invasive, well-differentiated mucinous adenocarcinoma with a villous adenoma on the neobladder ( Figure 1 ). (urotoday.com)
Domenico Trombetta, PhD, researcher, laboratory of oncology, Fondazione IRCCS Casa Sollievo della Sofferenza, discusses findings from an Italian multicenter cohort of patients with invasive mucinous adenocarcinoma, a rare histotype of lung adenocarcinoma. (onclive.com)
Domenico Trombetta, PhD, researcher, laboratory of oncology, Fondazione IRCCS Casa Sollievo della Sofferenza, discusses findings from an Italian multicenter cohort of patients with invasive mucinous adenocarcinoma (IMA), a rare histotype of lung adenocarcinoma. (onclive.com)
NRG1 fusions were recently reported as a new molecular feature of Invasive Mucinous Adenocarcinoma (IMA) of the lung. (oncotarget.com)
It may represent the mucinous counterpart of invasive micropapillary carcinoma. (nih.gov)
The objective of this study was to clarify the long-term outcome after surgical resection in patients with noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma. (fujita-hu.ac.jp)
We performed a retrospective review of the clinicopathological features and outcome in patients who underwent pancreatic resection for noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma between November 1982 and December 1997 at Chiba University Hospital. (fujita-hu.ac.jp)
The mean age of patients with either noninvasive (n = 16) or minimally invasive (n = 5) adenocarcinoma was 61 years. (fujita-hu.ac.jp)
Of the patients with minimally invasive adenocarcinoma, 4 had abdominal pain. (fujita-hu.ac.jp)
2 patients with minimally invasive adenocarcinoma and 1 with noninvasive adenocarcinoma. (fujita-hu.ac.jp)
Noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma had a favorable prognosis after surgical treatment. (fujita-hu.ac.jp)
Background: Survival after resection for invasive intraductal papillary mucinous neoplasm (inv-IPMN) is superior to pancreatic ductal adenocarcinoma (PDAC). (elsevier.com)
carcinomas in situ (5/14), IPMTs (2/5) and invasive adenocarcinomas (2/5) than in flat hyperplasia (0/6) or papillary hyperplasia (2/18). (elsevier.com)
A rare case of invasive mucinous adenocarcinoma of fallopian tube fimb" by S. X. Liang, T. C. Brandler et al. (hofstra.edu)

Trousseau syndrome often occurs with mucinous adenocarcinomas, which secrete abnormally glycosylated mucins and mucin fragments into the bloodstream. (jci.org)
A primary, usually low grade adenocarcinoma of the endometrium in which the majority of the malignant epithelial cells contain abundant intracytoplasmic mucin. (mycancergenome.org)
An adenocarcinoma is defined as mucinous when extracellular mucin corresponds to more than 50% of the lesion. (radiopaedia.org)
An adenocarcinoma producing mucin in significant amounts. (wakehealth.edu)
Cystoscopy and biopsy revealed an adenocarcinoma of the anterior bladder and stoma with extensive associated mucin production and a background of acute and chronic inflammation. (biomedcentral.com)
Mucinous and non-mucinous CRC were compared with regard to microsatellite status, overall mutation rate, the most frequently mutated genes, mutations in genes coding for mismatch repair (MMR) proteins and genes coding for mucin glycoproteins. (cdc.gov)
Mucinous adenocarcinoma was more likely to have mutations in genes coding for MMR proteins and mucin glycoproteins. (cdc.gov)
Based on its molecular context, mucinous colorectal adenocarcinoma is associated with the overexpression of mucin 2 (MUC2) and mucin 5AC (MUC5AC) proteins. (biomedcentral.com)
CT Differentiation of Mucinous and Nonmucinous Colorectal (http://www.ajronline.org/doi/full/10.2214/AJR.06.04 76) Mucinous colorectal carcinoma is a histologic subtype of adenocarcinoma characterized by abundant extracellular mucin production [1, 2]. (herbalous.com)
Adenocarcinoma , Mucinous Signet Ring Type - SurgPath4U (http://www.surgpath4u.com/caseviewer.php%3Fcase_no% 3D295) A pale glistening right sided mass suggests the high content of mucin . (herbalous.com)
Colorectal mucinous adenocarcinoma (MAC) and serrated adenocarcinoma (SAC) share many characteristics, including right-side colon location, frequent mucin production, and various molecular features. (ncku.edu.tw)

Histologic examination of the surgical specimens showed features of pure mucinous carcinoma with diffuse micropapillary architecture. (nih.gov)
The micropapillary variant of mammary mucinous carcinoma demonstrates characteristic cytologic and histologic features that warrant special attention. (nih.gov)
Tumoral lesions were divided to classic (68%) and atypic (32%) forms of OPA based on growth pattern and progression and two other forms of mucinous (56%) and non-mucinous (44%) of OPA based on histologic characterization of neoplastic secretory cells were descripted. (ac.ir)
In the gallbladder, mucinous adenocarcinoma is a rare histologic phenotype, and adenocarcinomas involving Rokitansky-Aschoff (RA) sinuses are uncommon, which were indeed found in a case reported here. (springeropen.com)
Mucinous adenocarcinoma of the gallbladder is a rare histologic phenotype, and adenocarcinomas involving Rokitansky-Aschoff sinuses (RA sinuses) are uncommon. (springeropen.com)
We evaluated epidemiologic trends and survival for bladder cancer histologic subtypes in California patients by comparing urothelial carcinoma of the bladder (UCB) and non-urothelial subtypes including squamous cell carcinoma (SCC), adenocarcinoma (ADC), and small-cell carcinoma (SmCC). (urotoday.com)

2 of 26 patients (7.7%) subsequently developed pancreatic ductal adenocarcinoma in the remnant pancreas, at 41 months and 137 months after surgery. (hindawi.com)
1 ] reported an important relationship between IPMN and ductal adenocarcinoma of the pancreas: IPMN is a strong risk factor for pancreatic cancer. (hindawi.com)
Ultrasonographic Characteristics of Intraductal Papillary Mucinous Neoplasm of the Pancreas [J]. Chinese Medical Sciences Journal, 2010, 25(3): 151-155. (cams.cn)
Intracystic papillary neoplasm (ICPN) of the gallbladder is a preinvasive neoplastic lesion and considered to share similar characteristics with intraductal papillary mucinous neoplasm (IPMN) and intraductal tubulopapillary neoplasm of the pancreas and intraductal papillary neoplasm of the extrahepatic bile duct. (springeropen.com)
Experimentally ductal adenocarcinomas of the pancreas can be induced in the hamster model by a brief treatment with N-nitroso (2-hydroxypropyl) (2-oxopropyl)amine (HPOP), while IPMTs can be induced by a combined treatment with HPOP and erotic acid (OA) in an initiational promotion schedule. (elsevier.com)
Pancreatic Mucinous Cystadenoma or Mucinous Cystadenoma of the pancreas (MCN) are a type of mucinous cystic neoplasm of the pancreas. (wikipedia.org)
Mucinous cystadenomas are in the dital pancreas in about 80% of the cases and distal pancreatectomy is needed for resection. (wikipedia.org)

Pure Mucinous Carcinoma of the Breast: a Clinicopathologic Analysis with 56 Patients [J]. Chinese Medical Sciences Journal, 2010, 25(2): 115-118. (cams.cn)
Mucinous carcinoma of the breast: Gross pathology (upper left) of mucinous carcinoma shows gelatinous areas. (wikipedia.org)

Frozen section and final pathology diagnosis revealed moderately differentiated adenocarcinoma arising in the left fimbria. (hofstra.edu)

For the mucinous carcinomas involving the remainder of the colon , please refer to the article on mucinous carcinoma of the colon . (radiopaedia.org)
We present 47 cases (1991 to 2006) of mucinous carcinomas treated by radical prostatectomy. (ovid.com)
The same study revealed that in contrast to squamous cell carcinomas in which HPV was detected in 87% of cases, only 62% of adenocarcinomas were found to be HPV positive. (nature.com)
Mucinous versus Nonmucinous Rectal Carcinomas: Differentiation (http://radiology.rsna.org/content/213/1/79.long) Mucinous rectal carcinoma is a histopathologic subtype of rectal adenocarcinoma that is No bowel preparation was given prior to the MR examination. (herbalous.com)
Previous attempts at subclassifying pure mucinous carcinomas of the breast based on architectural patterns and other associated features are on record. (nih.gov)
Over 40 percent of all mucinous carcinomas are colorectal. (wikipedia.org)

Mucinous adenocarcinoma of the colon and rectum: A genomic analysis. (cdc.gov)
Data from The Cancer Genome Atlas-colon adenocarcinoma and rectum adenocarcinoma projects were utilized. (cdc.gov)
Printable - Colorectal Mucinous Adenocarcinoma - Surgical (http://surgpathcriteria.stanford.edu/gitumors/color ectal-mucinous-adenocarcinoma/printable.html) Mucinous Adenocarcinoma of the Colon and Rectum. (herbalous.com)
Cancer Research UK : CancerHelp UK (http://www.cancerresearchuk.org/cancer-help/type/bo wel-cancer/about/types-of-bowel-cancer) There are one or two rare types of adenocarcinoma of the colon and rectum. (herbalous.com)
Incidence and survival of mucinous adenocarcinoma of the (http://www.ncbi.nlm.nih.gov/pubmed/14719155) Age standardized incidence rate was used to describe the incident pattern of mucinous adenocarcinoma of colon and rectum during a period of time. (herbalous.com)

Intestinal metaplasia of the urachal epithelium is the most frequent mechanism accounting for the majority of adenocarcinomas of the urachus. (biomedsearch.com)
Vitamin A contents of rat intestinal epithelium and jejunal mucinous adenocarcinoma. (docphin.com)
Concentrations of retinol and tetinyl esters were assayed in rat intestinal mucosa and in chemically induced transplanted mucinous adenocarcinoma of the jejunum. (docphin.com)
The concentration of vitamin A per cell in the adenocarcinoma tissue was about 20 times less than that in intestinal epithelium. (docphin.com)
However, we describe an unusual case of adenocarcinoma of the endometrium showing diffuse histological, immunohistochemical, and ultrastructural evidence of intestinal differentiation. (elsevier.com)
A case of intestinal mucinous adenocarcinoma with metastasis to gonadal tissue is reported. (bjvp.org.br)
Microscopically, intestinal lesion consisted of an adenocarcinoma (mucinous type), with infiltration of muscular layers and mesenteric adipose tissue. (bjvp.org.br)
Immunohistochemistry was positive for CDX2 and pancytokeratin, and negative for vimentin, supporting the diagnosis of intestinal mucinous adenocarcinoma with metastases to epididymis, testis and tunica albuginea. (bjvp.org.br)
We describe a case of simultaneous endocervical and intestinal-type mucinous differentiation with goblet cells arising in a FIGO grade 1 endometrioid adenocarcinoma. (biomedcentral.com)
Endometrioid adenocarcinoma with endocervical (A) and intestinal type (B) mucinous differentiation. (biomedcentral.com)
Classic endometrioid adenocarcinoma is seen in the left side of panel B adjacent to the intestinal-type metaplasia. (biomedcentral.com)
The pathological diagnosis was ICPN, intestinal type, with an associated mucinous adenocarcinoma arising in RA sinus. (springeropen.com)
Adenocarcinoma, intestinal type. (rexhealth.com)

In this paper we report a patient with pulmonary solid mass and thyroid nodule, initially diagnosed as metastatic thyroid carcinoma in whom postoperative resective surgery confirmed primary pulmonary mucinous adenocarcinoma with synchronous metastasis to thyroid. (erdogan.edu.tr)
Patients with mucinous adenocarcinoma had larger primary lesions, higher preoperative CEA levels, a deeper depth of invasion, higher rates of nodal and distant metastasis, and more metastatic sites. (biomedcentral.com)

Mucinous adenocarcinomas of the stomach and colon can demonstrate a sand-like calcific pattern. (diagnosticimaging.com)
Moreover, mucinous colorectal adenocarcinoma is more frequently located in the proximal colon and diagnosed at an advanced stage. (biomedcentral.com)
Chemotherapy for Mucinous Adenocarcinoma of the Colon - OncoLink (http://www.oncolink.org/experts/article1.cfm%3Fc%3D 40%26id%3D1380) Mucinous adenocarcinoma is a term that describes the way this colon cancer looks under a microscope. (herbalous.com)
Mucinous (colloid) carcinoma of colon . (herbalous.com)
The primary adenocarcinoma of urinary bladder creates a diagnostic dilemma, as it is difficult to differentiate metastatic adenocarcinoma of the colon and prostate. (sciepub.com)
We report a case of mucinous adenocarcinoma in the ascending colon . (bvsalud.org)

In this case report, we present radiographic findings of a case of mucinous adenocarcinoma of the bladder and suprapubic (SP) tract in a quadriplegic patient. (biomedcentral.com)

Our goal is to examine the association between use of systemic chemotherapy and survival in patients with metastatic low-grade mucinous appendiceal adenocarcinoma. (nih.gov)
They have a much more aggressiveness and show unusual metastatic patterns compared to usual type endocervical adenocarcinoma . (bvsalud.org)
[ 2 ] The metastatic carcinoma is the most common type of adenocarcinoma of urinary bladder. (sciepub.com)
A novel treatment approach prolonging survival in an uncommon metastatic primary bladder adenocarcinoma. (urotoday.com)

Differences in somatic mutation rate and CNV in genes associated with resistance to 5-FU, oxaliplatin, and irinotecan may partly account for the pattern of resistance observed in mucinous colorectal cancers. (cdc.gov)
[ 1 ] Adenocarcinomas account for less than 2% of all bladder cancers. (sciepub.com)
In order to investigate the role of K-ras in progression of IPMTs as compared with adenocarcinomas we have examined the presence of K-ras mutations in the above two types of experimentally induced pancreatic cancers, as well as in associated and preneoplastic lesions. (elsevier.com)
Pancreatic adenocarcinoma is the cancer arising from pancreatic ducts and the most common type of pancreatic cancers. (isciii.es)
The majority of gastric cancers are adenocarcinomas that begin in the innermost mucosal layer of the organ. (healthcentral.com)

Primary pulmonary mucinous adenocarcinoma (PPMA) is an uncommon subtype of lung adenocarcinoma. (spandidos-publications.com)
Qu Y, Che N, Zhao D, Zhang C, Su D, Zhou L, Zhang L, Wang C, Zhang H and Wei L: The clinicopathological significance of ALK rearrangements and KRAS and EGFR mutations in primary pulmonary mucinous adenocarcinoma. (spandidos-publications.com)
Primary adenocarcinoma of the bladder arises from the urachal remnants or from the bladder urothelium. (biomedsearch.com)
Since the patient fulfills the revised Bethesda criteria analysis of immunoreactivity of DNA mismatch repair proteins was performed showing loss of MLH1 and MSH2 expression associated with high microsatellite instability (MSI-H), not yet reported for primary mucinous appendiceal carcinoma. (jcancer.org)
Primary pulmonary mucinous adenocarcinom. (erdogan.edu.tr)
To the best of our knowledge, we report the first case with primary pulmonary mucinous adenocarcinoma at the age of 15. (erdogan.edu.tr)
144 patients with mucinous and 2673 with non-mucinous adenocarcinomas who underwent primary resection in two major centers in Yokohama, Japan were retrospectively evaluated for clinicopathological features and treatment factors. (biomedcentral.com)
Primary mucinous adenocarcinomas are uncommon, and their pathogenesis remains unclear. (elsevier.com)
We selected 45 mucinous adenocarcinoma cases from among 2474 surgically resected primary lung adenocarcinomas. (elsevier.com)
Primary Mucinous Adenocarcinoma of the Thymus: A Case Report and Literature Review[J].Chinese Medical Sciences Journal, 2017, 32(3): 201-203. (cams.cn)
Abdul-Ghafar J, Yong SJ, Kwon W, Park IH, Jung SH.Primary thymic mucinous adenocarcinoma: a case report. (cams.cn)
The primary mucinous adenocarcinoma of the bladder is an extremely rare urologic entity, which is less than 2% of all urinary bladder tumours and often presents in advanced stage. (sciepub.com)
A 68-year old gentleman was diagnosed with a primary mucinous adenocarcinoma of the bladder from biopsy of anterior abdominal wall ulcer. (sciepub.com)
Primary mucinous adenocarcinoma is a rare urological entity. (sciepub.com)
Primary bladder adenocarcinoma (PBA) is an epithelial malignancy with pure glandular differentiation, without evidence of typical urothelial (transitional cell) carcinoma. (urotoday.com)
Our aim is to provide updated information on primary and secondary bladder adenocarcinomas, with focus on pathologic features, differential diagnosis, and clinical relevance. (urotoday.com)
Cases of primary retroperitoneal mucinous cystadenoma (PRMC) are extremely rare. (wikipedia.org)

Mucinous adenocarcinoma is a pharmacogenomically distinct subtype of colorectal cancer. (cdc.gov)
Mucinous adenocarcinoma is a distinct subtype of colorectal cancer (CRC) with a worse prognosis when compared with non-mucinous adenocarcinoma. (cdc.gov)

In the subgroup analysis stratified by stage, Patients diagnosed as StageIII and IV disease had a worse survival in mucinous adenocarcinoma than non-mucinous, while survival did not differ significantly in patients diagnosed as Stage0-II disease. (biomedcentral.com)
Our study indentified that mucinous adenocarcinoma was associated with a worse survival compared with non-mucinous in patients with StageIII and IV disease. (biomedcentral.com)
Therefore, differential diagnosis of GAC from the usual type of endocervical adenocarcinoma is very important because they are related to a significant risk of recurrence and decreased 5-year disease -specific survival . (bvsalud.org)
Conflicting results are found in the literatures regarding the prognosis and overall survival (OS) of mucinous colorectal adenocarcinoma patients. (biomedcentral.com)

Human-Stomach poor differentiated mucinous adenocarcinoma, partly signet-ring cell carcinoma tissue section slide (paraffin embedded). (acris-antibodies.com)
The patients were stratified into three groups according to their histological type: mucinous carcinoma (MC), signet ring cell carcinoma (SRCC), and poorly differentiated carcinoma (PDC). (biomedcentral.com)
According to the Japanese classification for histological typing for GC, mucinous carcinoma (MC) or signet ring cell carcinoma (SRCC) is defined as the undifferentiated type [ 4 ]. (biomedcentral.com)
Diseases associated with KRT7 include Pseudomyxoma Peritonei and Signet Ring Cell Adenocarcinoma . (genecards.org)

The treatment of pancreatic adenocarcinoma includes surgical resection, chemotherapy, or radiotherapy depending on the clinical staging. (isciii.es)

The clinicopathological characteristics and outcomes of mucinous gastric adenocarcinoma (GC) remain unclear. (biomedcentral.com)
We recently reported the clinicopathologic characteristics of surgically resected mucinous adenocarcinoma, including the frequent involvement of the left and lower lung and absence of central fibrosis. (elsevier.com)
The current study clearly demonstrated that mucinous adenocarcinomas with KRAS mutations have clinicopathologic characteristics different from those of mucinous adenocarcinoma without such mutations. (elsevier.com)
This study determined the clinicopathologic characteristics and long-term outcome of stage I colorectal mucinous adenocarcinomas (MAC). (researchsquare.com)

Type III suggested intraductal papillary mucinous adenoma (IPMA), while type IV suggested intraductal papillary mucinous adenocarcinoma (IPMC). (hindawi.com)

Furthermore, mucinous (so-called colloid) adenocarcinoma, an unusual variant of pulmonary adenocarcinoma, is extremely rare in the first decade of life. (erdogan.edu.tr)

Endocervical-type mucinous differentiation in endometrioid adenocarcinoma is not uncommon. (biomedcentral.com)
Adenocarcinoma is an uncommon malignancy in the urinary bladder which may arise primarily in the bladder as well as secondarily from a number of other organs. (urotoday.com)

Five patients with pure mucinous carcinoma with diffuse micropapillary architecture were noted. (nih.gov)
Among the five patients with pure mammary mucinous carcinoma (micropapillary variant), three patients underwent preoperative fine-needle aspiration biopsies and had specimens available for review. (nih.gov)
Histologically, the mass was consisted of subserosal cysts lined by atypical columnar mucinous epithelium with micropapillary growth and nuclear stratification. (springeropen.com)
What does it mean if the following terms are used to describe the adenocarcinoma: papillary, micropapillary, acinar, mucinous, or solid? (cancer.org)

Tsuda, H. / Gross features of lobular endocervical glandular hyperplasia in comparison with minimal-deviation adenocarcinoma and stage Ib endocervical-type mucinous adenocarcinoma of the uterine cervix . (elsevier.com)

In an unadjusted analysis, the 5-year OS and CSS in patients with a mucinous adenocarcinoma (MC) was 76.8 % (95 % confidence interval (95 %CI): 72.1-81.7 %) and 81.0 % (95 %CI: 76.6-85.6 %), respectively, compared with 70.0 % (95 %CI: 65.1-75.3 %) and 76.2 % (95 %CI: 71.5-81.2 %) in patients with non-mucinous adenocarcinoma (NMC) (P = 0.082 and P = 0.368). (nih.gov)
We reviewed 62 patients with MGC and 104 patients with non-mucinous gastric carcinoma (NMGC), pathologically confirmed between 2003 and 2015. (oncotarget.com)

In this study we analyzed the clinicopathologic differences between MGC and non-mucinous gastric carcinoma (NMGC). (elsevier.com)
Mucinous gastric carcinoma (MGC) is a rare histological subtype of gastric cancer. (oncotarget.com)

In this study, we described the clinicopathological features of mucinous adenocarcinoma in Japan, to identify optimal therapeutic strategies. (biomedcentral.com)
The clinicopathological features of colorectal mucinous (http://www.wjso.com/content/10/1/109) Jun 15, 2012 However, previous studies show conflicting results regarding the prognosis of colorectal mucinous adenocarcinoma . (herbalous.com)

There are 2 clinical trials for endometrial mucinous adenocarcinoma, of which 2 are open and 0 are completed or closed. (mycancergenome.org)
ER and PR are the most frequent gene inclusion criteria for endometrial mucinous adenocarcinoma clinical trials [ 3 ]. (mycancergenome.org)
Abemaciclib, atezolizumab, and bevacizumab are the most common interventions in endometrial mucinous adenocarcinoma clinical trials. (mycancergenome.org)
Among 50 journal articles, we chose 33 studies describing the clinical sign and symptoms, pathophysiology, etiology, and association between mucinous anal adenocarcinoma and chronic peri-anal fistula. (cureus.com)
The aim of this review is to update the non-specialist clinician on the cause, clinical presentation, and current management of so called curable and incurable pancreatic adenocarcinomas. (bmj.com)
Appendiceal adenocarcinoma (AA) is an orphan disease with unique clinical attributes but often treated as colorectal cancer (CRC). (nature.com)
Appendiceal adenocarcinoma (AA) is an orphan malignancy (estimated 1 new case per 100,000 person per year) with unique clinical attributes that are distinct from colorectal cancer (CRC) (see Data Supplement Table S1 ). (nature.com)
Resistance to paclitaxel (PTX), the standard chemotherapy agent for treatment of lung adenocarcinoma, is a major clinical obstacle. (medworm.com)

Identification of Atypic and Classic, Mucinous and Nonmucinous Forms of Ovine Pulmonary Adenocarcinoma (OPA) and TTF1 Marker Expression', Iranian Journal of Veterinary Medicine , 11(3), pp. 279-287. (ac.ir)
BACKGROUND: Ovine pulmonary adenocarcinoma (OPA) is a worldwide contagious bronchioalveolar carcinoma caused by infection of a beta retrovirus in sheep and less in goat. (ac.ir)

Casali C, Rossi G, Marchioni A, Sartori G, Maselli F, Longo L, Tallarico E and Morandi U: A single institution-based retrospective study of surgically treated bronchioloalveolar adenocarcinoma of the lung: Clinicopathologic analysis, molecular features and possible pitfalls in routine practice. (spandidos-publications.com)
In this review, we discuss the molecular background and histopathology of mucinous colorectal adenocarcinoma, and provide an update on its prognosis and therapeutics from recent literatures. (biomedcentral.com)
Molecular assessments have revealed significant differences between mucinous and non-mucinous colorectal adenocarcinoma, suggesting a different mechanism of oncogenesis. (biomedcentral.com)
In this review, we aimed at discussing the molecular background and histopathology of mucinous colorectal adenocarcinoma, and to evaluate the effects of different treatments provided to these patients at different stages. (biomedcentral.com)

In addition, the non-tumorous fimbria epithelium showed a spectrum of mucinous alterations with variable nuclear atypia: cytologically bland areas that were reminiscent of mucinous metaplasia were positive for p53 and showed minimal proliferation as assessed by Ki-67, and cytologically atypical stratified mucinous epithelium that was positive for p53 and Ki-67. (hofstra.edu)
Immunohistochemical stains showed that the cells were positive for CK7 and CK20, monoclonal antibodies for labeling epithelium of gastrointestinal tract, especially adenocarcinoma. (isciii.es)

There has been considerable controversy over the prognosis of mucinous gastric adenocarcinoma (MGC). (elsevier.com)
The prognosis of mucinous colorectal adenocarcinoma as to non-mucinous colorectal adenocarcinoma is debatable. (biomedcentral.com)
Further, there is a persisting debate in regard to the prognosis of mucinous colorectal adenocarcinoma as compared to its non-mucinous counterpart. (biomedcentral.com)

Endometrial biopsy revealed a well differentiated endometrioid adenocarcinoma, FIGO grade 1, arising in a background of complex atypical hyperplasia. (biomedcentral.com)
This distinction between squamous cell carcinoma and adenocarcinoma may be especially difficult in small biopsy specimens. (cancer.org)

Gastric type mucinous endocervical adenocarcinomas of the uterine cervix (GAC) are a newly classified mucinous subtype with morphologically in 2014, WHO . (bvsalud.org)

However, the signaling pathways and driver genes in smoking-associated lung adenocarcinoma remain unknown. (medworm.com)

Anatomy17

Organisms4

Diseases78

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment48

Psychiatry and Psychology1

Phenomena and Processes19

Disciplines and Occupations2

Information Science5

Health Care15

Increased expression of the RIalpha subunit of the cAMP-dependent protein kinase A is associated with advanced stage ovarian cancer. (1/804)

Combined inhibin and CA125 assays in the detection of ovarian cancer. (2/804)

Clinicopathologic characteristics of mucinous gastric adenocarcinoma. (3/804)

Tumor characteristics and clinical outcome of tubular and mucinous breast carcinomas. (4/804)

Overexpression of H-Ryk in mouse fibroblasts confers transforming ability in vitro and in vivo: correlation with up-regulation in epithelial ovarian cancer. (5/804)

Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast. (6/804)

Paradoxical correlations of cyclin-dependent kinase inhibitors p21waf1/cip1 and p27kip1 in metastatic colorectal carcinoma. (7/804)

Carcinoma of the axillary breast. (8/804)

Adenocarcinoma

Adenocarcinoma, Mucinous

Lung Neoplasms

Pancreatic Neoplasms

Esophageal Neoplasms

Adenocarcinoma, Papillary

Barrett Esophagus

Carcinoma, Pancreatic Ductal

Adenocarcinoma, Bronchiolo-Alveolar

Stomach Neoplasms

Cardia

Immunohistochemistry

Colonic Neoplasms

Tumor Markers, Biological

Esophagogastric Junction

Neoplasm Staging

Prognosis

Keratin-7

Gene Expression Regulation, Neoplastic

Cell Line, Tumor

Carcinoma, Squamous Cell

Endometrial Neoplasms

Neoplasms, Multiple Primary

Precancerous Conditions

Intestinal Neoplasms

Prostatic Neoplasms

Tumor Cells, Cultured

Duodenal Neoplasms

Carcinoma, Signet Ring Cell

Carcinoma, Endometrioid

Cecal Neoplasms

Mammary Neoplasms, Experimental

Neoplasm Invasiveness

Adenocarcinoma, Clear Cell

Metaplasia

Immunoenzyme Techniques

Colorectal Neoplasms

Rectal Neoplasms

Ampulla of Vater

Genes, ras

Common Bile Duct Neoplasms

Keratin-20

Tissue Array Analysis

Ileal Neoplasms

Adenoma

Pancreaticoduodenectomy

DNA, Neoplasm

Jejunal Neoplasms

Survival Rate

Neoplasm Metastasis

Lymphatic Metastasis

Neoplasm Proteins

Carcinoma, Non-Small-Cell Lung

Carcinoma, Adenosquamous

Carcinoembryonic Antigen

Carcinoma, Acinar Cell

Neoplasm Transplantation

Esophagus

Disease Progression

Survival Analysis

Retrospective Studies

Gastrectomy

Mice, Nude

RNA, Messenger

Paranasal Sinus Neoplasms

Mutation

Carcinoma in Situ

Receptor, Epidermal Growth Factor

Antineoplastic Agents

Kaplan-Meier Estimate

Reverse Transcriptase Polymerase Chain Reaction

Biopsy

Pancreatectomy

Fatal Outcome

Antigens, Neoplasm

Uterine Cervical Neoplasms

Treatment Outcome

Mucins

Gastrointestinal Neoplasms

Tumor Suppressor Protein p53