AnatomyOrganismsChemicals and DrugsPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation Science
Adenine Nucleotide Translocator 1Mitochondrial ADP, ATP TranslocasesAdenine Nucleotide Translocator 2AtractylosideBongkrekic AcidAdenine NucleotidesAdenine Nucleotide Translocator 3Oxidative PhosphorylationMitochondriaMitochondria, LiverNucleotidyltransferasesIntracellular MembranesAdenosine DiphosphateAdenosine TriphosphateVoltage-Dependent Anion ChannelsMitochondrial Membrane Transport ProteinsMitochondrial SwellingMitochondria, HeartAdenineOxygen ConsumptionCyclophilinsMembrane Potential, MitochondrialUncoupling AgentsCell RespirationPermeabilityAryl Hydrocarbon Receptor Nuclear TranslocatorProto-Oncogene Proteins c-bcl-2Mitochondrial ProteinsNucleotidesMolecular Sequence DataApoptosisMembrane PotentialsKineticsDNA, MitochondrialAdenosine MonophosphateMyocardiumReceptors, GABAReceptors, Aryl HydrocarbonEnergy MetabolismPurine NucleotidesAmino Acid SequenceGuanine NucleotidesAdenosineBase SequenceHypoxanthinesAntsBiologyCreatine KinaseAdenylate KinaseNational SocialismPetunia
Adenine Nucleotide Translocator 1
A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM) and skeletal muscle (MUSCLE, SKELETAL).
Mitochondrial ADP, ATP Translocases
A class of nucleotide translocases found abundantly in mitochondria that function as integral components of the inner mitochondrial membrane. They facilitate the exchange of ADP and ATP between the cytosol and the mitochondria, thereby linking the subcellular compartments of ATP production to those of ATP utilization.
Adenine Nucleotide Translocator 2
A subtype of mitochondrial ADP, ATP translocase found primarily in FIBROBLASTS.
Atractyloside
A glycoside of a kaurene type diterpene that is found in some plants including Atractylis gummifera (ATRACTYLIS); COFFEE; XANTHIUM, and CALLILEPIS. Toxicity is due to inhibition of ADENINE NUCLEOTIDE TRANSLOCASE.
Bongkrekic Acid
An antibiotic produced by Pseudomonas cocovenenans. It is an inhibitor of MITOCHONDRIAL ADP, ATP TRANSLOCASES. Specifically, it blocks adenine nucleotide efflux from mitochondria by enhancing membrane binding.
Adenine Nucleotides
Adenine Nucleotide Translocator 3
A subtype of mitochondrial ADP, ATP translocase found primarily in the LIVER.
Oxidative Phosphorylation
Electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds.
Mitochondria
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
Mitochondria, Liver
Mitochondria in hepatocytes. As in all mitochondria, there are an outer membrane and an inner membrane, together creating two separate mitochondrial compartments: the internal matrix space and a much narrower intermembrane space. In the liver mitochondrion, an estimated 67% of the total mitochondrial proteins is located in the matrix. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p343-4)
Nucleotidyltransferases
A class of enzymes that transfers nucleotidyl residues. EC 2.7.7.
Intracellular Membranes
Thin structures that encapsulate subcellular structures or ORGANELLES in EUKARYOTIC CELLS. They include a variety of membranes associated with the CELL NUCLEUS; the MITOCHONDRIA; the GOLGI APPARATUS; the ENDOPLASMIC RETICULUM; LYSOSOMES; PLASTIDS; and VACUOLES.
Adenosine Diphosphate
Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Adenosine Triphosphate
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Voltage-Dependent Anion Channels
A family of voltage-gated eukaryotic porins that form aqueous channels. They play an essential role in mitochondrial CELL MEMBRANE PERMEABILITY, are often regulated by BCL-2 PROTO-ONCOGENE PROTEINS, and have been implicated in APOPTOSIS.
Mitochondrial Membrane Transport Proteins
Proteins involved in the transport of specific substances across the membranes of the MITOCHONDRIA.
Mitochondrial Swelling
An increase in MITOCHONDRIAL VOLUME due to an influx of fluid; it occurs in hypotonic solutions due to osmotic pressure and in isotonic solutions as a result of altered permeability of the membranes of respiring mitochondria.
Mitochondria, Heart
The mitochondria of the myocardium.
Adenine
A purine base and a fundamental unit of ADENINE NUCLEOTIDES.
Oxygen Consumption
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
Cyclophilins
A family of peptidyl-prolyl cis-trans isomerases that bind to CYCLOSPORINS and regulate the IMMUNE SYSTEM. EC 5.2.1.-
Membrane Potential, Mitochondrial
The voltage difference, normally maintained at approximately -180mV, across the INNER MITOCHONDRIAL MEMBRANE, by a net movement of positive charge across the membrane. It is a major component of the PROTON MOTIVE FORCE in MITOCHONDRIA used to drive the synthesis of ATP.
Uncoupling Agents
Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes.
Cell Respiration
The metabolic process of all living cells (animal and plant) in which oxygen is used to provide a source of energy for the cell.
Permeability
Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.
Aryl Hydrocarbon Receptor Nuclear Translocator
Aryl hydrocarbon receptor nuclear translocator is a basic HELIX-LOOP-HELIX MOTIF containing protein that forms a complex with DIOXIN RECEPTOR. The complex binds xenobiotic regulatory elements and activates transcription of a variety of genes including UDP GLUCURONOSYLTRANSFERASE. AhR nuclear translocator is also a subunit of HYPOXIA-INDUCIBLE FACTOR 1.
Proto-Oncogene Proteins c-bcl-2
Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.
Mitochondrial Proteins
Proteins encoded by the mitochondrial genome or proteins encoded by the nuclear genome that are imported to and resident in the MITOCHONDRIA.
Nucleotides
The monomeric units from which DNA or RNA polymers are constructed. They consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Apoptosis
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Membrane Potentials
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
Kinetics
The rate dynamics in chemical or physical systems.
DNA, Mitochondrial
Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins.
Adenosine Monophosphate
Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
Myocardium
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
Receptors, GABA
Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
Receptors, Aryl Hydrocarbon
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
Energy Metabolism
The chemical reactions involved in the production and utilization of various forms of energy in cells.
Purine Nucleotides
Purines attached to a RIBOSE and a phosphate that can polymerize to form DNA and RNA.
Amino Acid Sequence
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Guanine Nucleotides
Adenosine
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
Base Sequence
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Hypoxanthines
Purine bases related to hypoxanthine, an intermediate product of uric acid synthesis and a breakdown product of adenine catabolism.
Ants
Insects of the family Formicidae, very common and widespread, probably the most successful of all the insect groups. All ants are social insects, and most colonies contain three castes, queens, males, and workers. Their habits are often very elaborate and a great many studies have been made of ant behavior. Ants produce a number of secretions that function in offense, defense, and communication. (From Borror, et al., An Introduction to the Study of Insects, 4th ed, p676)
Biology
One of the BIOLOGICAL SCIENCE DISCIPLINES concerned with the origin, structure, development, growth, function, genetics, and reproduction of animals, plants, and microorganisms.
Creatine Kinase
A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Adenylate Kinase
An enzyme that catalyzes the phosphorylation of AMP to ADP in the presence of ATP or inorganic triphosphate. EC 2.7.4.3.
National Socialism
The doctrines and policies of the Nazis or the National Social German Workers party, which ruled Germany under Adolf Hitler from 1933-1945. These doctrines and policies included racist nationalism, expansionism, and state control of the economy. (from Columbia Encyclopedia, 6th ed. and American Heritage College Dictionary, 3d ed.)
Petunia
A plant genus of the family SOLANACEAE. Members contain steroidal glycosides.

Induction of an unregulated channel by mutations in adenine nucleotide translocase suggests an explanation for human ophthalmoplegia. (1/69)

Adenine nucleotide translocase (Ant) is primarily involved in ATP/ADP exchange across the mitochondrial inner membrane. Recently, the A114P missense mutation in the human Ant1 protein was found to be associated with autosomal dominant progressive external ophthalmoplegia (adPEO). Ant1(A114P) was proposed to cause an imbalance of the mitochondrial deoxynucleotide pool that subsequently affects the accuracy of mtDNA replication, thereby leading to accumulation of mutant mtDNA. In the present study, it has been shown that the A128P mutation of the Saccharomyces cerevisiae Aac2 protein, equivalent to A114P in human Ant1p, does not always affect respiratory growth. However, expression of aac2(A128P) results in depolarization, structural swelling and disintegration of mitochondria, and ultimately an arrest of cell growth in a dominant-negative manner. The aac2(A128P) mutation likely induces an unregulated channel allowing free passage of solutes across the inner membrane. These data raise the possibility that the formation of an unregulated channel, rather than a defect in ATP/ADP exchange, is a direct pathogenic factor in human adPEO. The accumulation of mtDNA mutations might be a consequence of mitochondrial dysfunction.  (+info)

Skeletal muscle mitochondrial free-fatty-acid content and membrane potential sensitivity in different thyroid states: involvement of uncoupling protein-3 and adenine nucleotide translocase. (2/69)

The effect of triiodothyronine (T3) on mitochondrial efficiency could be related to an increase in the concentrations of some proteins, such as uncoupling proteins (UCPs). Free fatty acids (FFA) seem to be a cofactor essential for the uncoupling activity of UCP3. In this paper, we report that the hypothyroidism-hyperthyroidism transition is accompanied by increases: (i) in the endogenous levels of mitochondrial FFA and (ii) in the sensitivity to FFA shown by the mitochondrial respiration rate and membrane potential, which correlated with the level of UCP3 protein. The level of the mRNA for adenine-nucleotide translocase-1 (ANT) was not affected by the thyroid state, while the ANT contribution to FFA-induced changes in mitochondrial uncoupling was low in the hypothyroid and euthyroid states but became more relevant in the hyperthyroid state at the highest concentration of FFA.  (+info)

Hypothermia preserves myocardial function and mitochondrial protein gene expression during hypoxia. (3/69)

Hypothermia before and/or during no-flow ischemia promotes cardiac functional recovery and maintains mRNA expression for stress proteins and mitochondrial membrane proteins (MMP) during reperfusion. Adaptation and protection may occur through cold-induced change in anaerobic metabolism. Accordingly, the principal objective of this study was to test the hypothesis that hypothermia preserves myocardial function during hypoxia and reoxygenation. Hypoxic conditions in these experiments were created by reducing O2 concentration in perfusate, thereby maintaining or elevating coronary flow (CF). Isolated Langendorff-perfused rabbit hearts were subjected to perfusate (Po2 = 38 mmHg) with glucose (11.5 mM) and perfusion pressure (90 mmHg). The control (C) group was at 37 degrees C for 30 min before and 45 min during hypoxia, whereas the hypothermia (H) group was at 29.5 degrees C for 30 min before and 45 min during hypoxia. Reoxygenation occurred at 37 degrees C for 45 min for both groups. CF increased during hypoxia. The H group markedly improved functional recovery during reoxygenation, including left ventricular developed pressure (DP), the product of DP and heart rate, dP/dtmax, and O2 consumption (MVo2) (P < 0.05 vs. control). MVo2 decreased during hypothermia. Lactate and CO2 gradients across the coronary bed were the same in C and H groups during hypoxia, implying similar anaerobic metabolic rates. Hypothermia preserved MMP betaF1-ATPase mRNA levels but did not alter adenine nucleotide translocator-1 or heat shock protein-70 mRNA levels. In conclusion, hypothermia preserves cardiac function after hypoxia in the hypoxic high-CF model. Thus hypothermic protection does not occur exclusively through cold-induced alterations in anaerobic metabolism.  (+info)

Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5-HT2B receptor signaling. (4/69)

Identification of factors regulating cardiomyocyte survival and growth is important to understand the pathogenesis of congenital heart diseases. Little is known about the molecular mechanism of cardiac functions triggered by serotonin. The link between signaling circuitry of external stimuli and the mitochondrial apoptotic machinery is of wide interest in cardiac diseases. Using cultured cardiomyocytes and 5-hydroxytryptamine (5-HT)2B-receptor knockout mice as an animal model of dilated cardiomyopathy, for the first time we show that serotonin via the Gq-coupled 5-HT2B-receptor protect cardiomyocytes against serum deprivation-induced apoptosis as manifested by DNA fragmentation, nuclear chromatin condensation, and TUNEL labeling. Serotonin prevents cytochrome c release and caspase-9 and -3 activation after serum deprivation via cross-talks between phosphatidylinositol-3 kinase/Akt and extracellular signal-regulated kinase (ERK) 1/2 signaling pathways. Serotonin binding to 5-HT2B-receptor activates ERK kinases to inhibit Bax expression induced by serum deprivation. Serotonin via phosphatidylinositol-3 kinase/Akt can activate NF-kappaB that is required for the regulation of the mitochondrial adenine nucleotide translocator (ANT-1). Parallel to these observations, ultrastructural analysis in the 5-HT2B-receptor knockout mice heart revealed pronounced mitochondrial defects in addition to altered mitochondrial enzyme activities (cytochrome oxidase and succinate dehydrogenase) and ANT-1 and Bax expressions. These findings identify 5-HT as a novel survival factor targeting mitochondria in cardiomyocytes.  (+info)

A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells. (5/69)

Mitochondria are the powerhouse of the cell and their disruption leads to cell death. We have used a peptide trivalent arsenical, 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO), to inactivate the adenine nucleotide translocator (ANT) that exchanges matrix ATP for cytosolic ADP across the inner mitochondrial membrane and is the key component of the mitochondrial permeability transition pore (MPTP). GSAO triggered Ca(2+)-dependent MPTP opening by crosslinking Cys(160) and Cys(257) of ANT. GSAO treatment caused a concentration-dependent increase in superoxide levels, ATP depletion, mitochondrial depolarization, and apoptosis in proliferating, but not growth-quiescent, endothelial cells. Endothelial cell proliferation drives new blood vessel formation, or angiogenesis. GSAO inhibited angiogenesis in the chick chorioallantoic membrane and in solid tumors in mice. Consequently, GSAO inhibited tumor growth in mice with no apparent toxicity at efficacious doses.  (+info)

Increased adenine nucleotide translocator 1 in reactive astrocytes facilitates glutamate transport. (6/69)

A hallmark of central nervous system (CNS) pathology is reactive astrocyte production of the chronic glial scar that is inhibitory to neuronal regeneration. The reactive astrocyte response is complex; these cells also produce neurotrophic factors and are responsible for removal of extracellular glutamate, the excitatory neurotransmitter that rises to neurotoxic levels in injury and disease. To identify genes expressed by reactive astrocytes, we employed an in vivo model of the glial scar and differential display PCR and found an increase in the level of Ant1, a mitochondrial ATP/ADP exchanger that facilitates the flux of ATP out of the mitochondria. Ant1 expression in reactive astrocytes is regulated by transforming growth factor-beta1, a pluripotent CNS injury-induced cytokine. The significance of increased Ant1 is evident from the observation that glutamate uptake is significantly decreased in astrocytes from Ant1 null mutant mice while a specific Ant inhibitor reduces glutamate uptake in wild-type astrocytes. Thus, the astrocytic response to CNS injury includes an apparent increase in energy mobilization capacity by Ant1 that contributes to neuroprotective, energy-dependent glutamate uptake.  (+info)

Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity. (7/69)

Mitochondrial permeability transition (MPT) has been proposed to play a key role in cell death. Downstream MPT events include the release of apoptogenic factors that sets in motion the mitochondrial apoptosome leading to caspase activation. The current work examined the regulation of MPT by membrane fluidity modulated upon cholesterol enrichment. Mitochondria enriched in cholesterol displayed increased microviscosity resulting in impaired MPT induced by atractyloside, a c-conformation stabilizing ligand of the adenine nucleotide translocator (ANT). This effect was dependent on the dose of cholesterol loaded and reversed upon the fluidization of mitochondria by the fatty acid derivative A2C. Mitoplasts derived from cholesterol-enriched mitochondria responded to atractyloside in a similar fashion as intact mitochondria, indicating that a significant amount of cholesterol is still found in the inner membrane. The effects of cholesterol on MPT induced by atractyloside were mirrored by the release of intermembrane proteins, cytochrome c, Smac/Diablo, and apoptosis inducing factor. However, cholesterol loading did not affect the uptake rate of adenine nucleotide hence dissociating the function of ANT as a MPT-mediated protein from its adenine nucleotide exchange function. Thus, these findings indicate that the ability of atractyloside to induce MPT via ANT requires an appropriate membrane fluidity range.  (+info)

Protein components of mitochondrial DNA nucleoids in higher eukaryotes. (8/69)

Mitochondrial DNA (mtDNA) is not packaged in nucleosomal particles, but has been reported to associate with the mitochondrial inner membrane. Gentle lysis of Xenopus oocyte mitochondria with nonionic detergent liberates a nucleoprotein complex containing mtDNA associated with a previously characterized DNA binding partner, mitochondrial transcription factor A (mtTFA), as well as a series of inner membrane proteins identified by sequencing. More extensive detergent treatment stripped most of these proteins from the DNA, leaving a limited number of proteins in a nucleoid core. Sequencing of the major proteins retained in association with mtDNA revealed the expected mtDNA binding proteins, mtTFA and mitochondrial single-stranded DNA binding protein (mtSSB), as well as four proteins not previously reported to associate with mtDNA. These include adenine nucleotide translocator 1, the lipoyl-containing E2 subunits of pyruvate dehydrogenase and branched chain alpha-ketoacid dehydrogenase and prohibitin 2. The association of several of these proteins with mtTFA-containing mtDNA nucleoids was confirmed by immunoprecipitation.  (+info)

Adenine nucleotide translocator synonyms, Adenine nucleotide translocator antonyms - FreeThesaurus.comAdenine nucleotide translocator synonyms, Adenine nucleotide translocator antonyms - FreeThesaurus.com
Synonyms for Adenine nucleotide translocator in Free Thesaurus. Antonyms for Adenine nucleotide translocator. 1 synonym for adenine: A. What are synonyms for Adenine nucleotide translocator?
https://www.freethesaurus.com/Adenine+nucleotide+translocator
Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2...Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2...
In brown-fat mitochondria, fatty acids induce thermogenic uncoupling through activation of UCP1 (uncoupling protein 1). However, even in brown-fat mitochondria from UCP1−/− mice, fatty-acid-induced uncoupling exists. In the present investigation, we used the inhibitor CAtr (carboxyatractyloside) to examine the involvement of the ANT (adenine nucleotide translocator) in the mediation of this UCP1-independent fatty-acid-induced uncoupling in brown-fat mitochondria. We found that the contribution of ANT to fatty-acid-induced uncoupling in UCP1−/− brown-fat mitochondria was minimal (whereas it was responsible for nearly half the fatty-acid-induced uncoupling in liver mitochondria). As compared with liver mitochondria, brown-fat mitochondria exhibit a relatively high (UCP1-independent) basal respiration (proton leak). Unexpectedly, a large fraction of this high basal respiration was sensitive to CAtr, whereas in liver mitochondria, basal respiration was CAtr-insensitive. Total ANT protein ...
https://portlandpress.com/biochemj/article-abstract/399/3/405/41792/Carboxyatractyloside-effects-on-brown-fat
Slc25a13 (untagged) - Mouse solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 ...Slc25a13 (untagged) - Mouse solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 ...
Slc25a13 (untagged) - Mouse solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 (Slc25a13), nuclear gene encoding mitochondrial protein, transcript variant 1, (10ug), 10 µg.
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Slc25a4 (untagged) - Mouse solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (cDNA...Slc25a4 (untagged) - Mouse solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (cDNA...
Slc25a4 (untagged) - Mouse solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (cDNA clone, (10ug), 10 µg.
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Selleck Chemicals Blog-Icaritin activates JNK-dependent mPTP necrosis pathway in colorectal cancer cellsSelleck Chemicals Blog-Icaritin activates JNK-dependent mPTP necrosis pathway in colorectal cancer cells
The colorectal cancer (CRC) is one leading contributor of cancer-related mortality worldwide. The search for effective anti-CRC agents is valuable. In the current study, we showed that icaritin (ICT), an active natural ingredient from the Chinese plant Epimedium, potently inhibited proliferation and survival of established (HT-29, HCT-116, DLD-1, and SW-620) and primary (patient-derived) CRC cells. Significantly, ICT mainly induced necrosis, but not apoptosis, in CRC cells. The necrosis inhibitor necrostatin-1 attenuated ICT-mediated cytotoxicity in CRC cells. We showed that ICT treatment in CRC cells induced mitochondrial permeability transition pore (mPTP) opening, which was evidenced by mitochondrial membrane potential (MMP) decrease and mitochondrial adenine nucleotide translocator-1 (ANT-1)-cyclophilin-D (CyPD) association. On the other hand, mPTP blockers, including sanglifehrin A, cyclosporin A, and bongkrekic acid, as well as siRNA-mediated knockdown of mPTP component (CyPD or ANT-1), ...
https://www.selleckchem.com/blog/Icaritin-activates-JNK-dependent-mPTP-necrosis-pathway-in-colorecta-cancer-cells.html?pathway=logical_ER_stress_UPR
Anti-Adenine Nucleotide Translocator 2 antibody (ab118125)Anti-Adenine Nucleotide Translocator 2 antibody (ab118125)
Rabbit polyclonal Adenine Nucleotide Translocator 2 antibody validated for WB, IP and tested in Human. With 2 independent reviews. Immunogen corresponding to…
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Abstract 1295: Mitochondrial Uncoupling in db/db Mouse Hearts is Mediated by the Adenine Nucleotide Translocator (ANT) |...Abstract 1295: Mitochondrial Uncoupling in db/db Mouse Hearts is Mediated by the Adenine Nucleotide Translocator (ANT) |...
Diabetes increases myocardial FA oxidation and MVO2, but underlying mechanisms are partially understood. We used perfused hearts, permeabilized fibers (fibers) and isolated mitochondria from diabetic db/db mice to assess mitochondrial (MITO) uncoupling and to elucidate underlying molecular mechanisms. MITO uncoupling and reduced cardiac efficiency (CE) was absent in hearts perfused with glucose alone. However, in db/db hearts perfused with 1.0 mM Palmitate and 11mM glucose, RPP was reduced by 31% p, 0.02, MVO2 was increased by 45% p, 0.03, and CE reduced by 51% p,0.004. In fibers, state 3 respirations with palmitoyl carnitine were similar (16.4±1.3 and 16.7±1.5 nmol/min/mg), but ATP production rates were reduced by 36% in db/db fibers so that ATP/O ratios were 1.5±0.2 in db/db vs. 2.5±0.1 in controls (p,0.005), indicating FA-induced mitochondrial uncoupling. H2O2 production was also increased by 2.6 fold (p,0.001) in isolated db/db MITO exposed to the complex 1 substrate pyruvate. To ...
http://circ.ahajournals.org/content/114/Suppl_18/II_244.5
Mitochondriales TRNG-GenMitochondriales TRNG-Gen
Graham BH et al. (1997) A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator.. [^] ...
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anti-SLC25A31 antibody | GeneTexanti-SLC25A31 antibody | GeneTex
SLC25A31 antibody (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31) for ELISA, WB. Anti-SLC25A31 pAb (GTX87816) is tested in Human, Mouse samples. 100% Ab-Assurance.
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Biology Resources | Grinnell CollegeBiology Resources | Grinnell College
Planning Your Courses Sample Schedules Biology 1st year Fall - Bio 150 or Chm 129; Math 131 (123) 1st year Spring - Bio 150 or Chm 129; **Math 133 (124) 2nd year Fall - Bio 251; Chm 221++ 2nd year Spring - Bio 252; **Chm 222 or **Math 209 3rd and 4th years - 5 electives* (can include summer research or classes). A maximum of four credits of advanced work in a related field may be applied toward the major. The following courses are on the approved list: ANT-221 or ANT-325; BCM-262; PSY-336.
https://www.grinnell.edu/academics/areas/biology/resources?qt-search_block=2
Adenine nucleotide translocator 1 | definition of adenine nucleotide translocator 1 by Medical dictionaryAdenine nucleotide translocator 1 | definition of adenine nucleotide translocator 1 by Medical dictionary
Looking for online definition of adenine nucleotide translocator 1 in the Medical Dictionary? adenine nucleotide translocator 1 explanation free. What is adenine nucleotide translocator 1? Meaning of adenine nucleotide translocator 1 medical term. What does adenine nucleotide translocator 1 mean?
http://medical-dictionary.thefreedictionary.com/adenine+nucleotide+translocator+1
Adenine Nucleotide Translocator 1 Summary Report | CureHunterAdenine Nucleotide Translocator 1 Summary Report | CureHunter
Adenine Nucleotide Translocator 1: A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM) and skeletal muscle (MUSCLE, SKELETAL).
http://www.curehunter.com/public/keywordSummaryD033741-Adenine-Nucleotide-Translocator-1.do
Short-hairpin RNA-induced suppression of adenine nucleotide translocase-2 in breast cancer cells restores their susceptibility...Short-hairpin RNA-induced suppression of adenine nucleotide translocase-2 in breast cancer cells restores their susceptibility...
The four known human ANT isoforms (ANT1, ANT2, ANT3, and ANT4) exhibit tissue-, cell-type-, and developmental stage-specific expression patterns [18]. ANT1 is strongly expressed in terminally differentiated cells; ANT2 is overexpressed in tissues that have high proliferative ability and in several cancer cell lines [16, 21]; and ANT3 is ubiquitously expressed in all tissues. Whereas ANT1 and ANT3 exert pro-apoptotic effects when overexpressed, ANT2, instead, has an anti-apoptotic function [20, 28]. We previously observed that ANT2 is overexpressed in the breast cancer cell lines MCF7 and MDA-MB-231 but is absent from the non-neoplastic mammary epithelial cell line MCF10A [16]. Moreover, vector-based RNAi knockdown of ANT2 expression in MCF7 and MDA-MB-231 cells resulted in cell cycle arrest and apoptotic cell death; these events were accompanied by cellular energy (ATP) depletion, mitochondrial membrane depolarization, Bax induction, and Bcl-xL down-regulation [16]. TNF-α and TNF receptor I ...
https://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-9-262
Anti-SLC47A1 / MATE1 Antibody | #ANT-131 | Alomone LabsAnti-SLC47A1 / MATE1 Antibody | #ANT-131 | Alomone Labs
Anti-SLC47A1 Antibody from Alomone Labs is a highly specific rabbit polyclonal Ab directed against an epitope of the mouse MATE-1. Applications: WB. Free samples available. Control antigen included. Lyophilized. Global shipping at room temperature. Your top supplier for Multidrug and toxin extrusion protein research!
https://www.alomone.com/p/anti-mate1/ANT-131
291 F.3d 1 | LexRoll.com291 F.3d 1 | LexRoll.com
19. EPA argues that its bifurcated approach to determining appropriate BART controls is permissible because § 169A(g)(2) is unclear about how a state must analyze anticipated visibility improvement. See Chevron U.S.A., Inc. v. Natural Res. Def. Council, 467 U.S. 837, 842-43, 104 S.Ct. 2778, 2781-82, 81 L.Ed.2d 694 (1984). We cannot agree. The Haze Rules splitting of the statutory factors is consistent with neither the text nor the structure of the statute. See 42 U.S.C. § 7491(g)(2). All five § 169A(g)(2) factors inform the states inquiries into what BART controls are appropriate for particular sources. Although no weights were assigned, the factors were meant to be considered together by the states. The language of § 169A(g)(2) can be read in no other way. To treat one of the five statutory factors in such a dramatically different fashion distorts the judgment Congress directed the states to make for each BART-eligible source. This is most apparent with respect to the states duty to take ...
http://circuitcourts.lexroll.com/2016/08/10/291-f-3d-1/
Thermogenin - WikipediaThermogenin - Wikipedia
Thermogenin (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1) is an uncoupling protein found in the mitochondria of brown adipose tissue (BAT). It is used to generate heat by non-shivering thermogenesis, and makes a quantitatively important contribution to countering heat loss in neonates which would otherwise occur due to their high surface area-volume ratio. UCPs are transmembrane proteins that decrease the proton gradient generated in oxidative phosphorylation. They do this by increasing the permeability of the inner mitochondrial membrane, allowing protons that have been pumped into the intermembrane space to return to the mitochondrial matrix. UCP1-mediated heat generation in brown fat uncouples the respiratory chain, allowing for fast substrate oxidation with a low rate of ATP production. UCP1 is related to other mitochondrial metabolite transporters such as the adenine nucleotide translocator, a proton channel in the mitochondrial inner membrane ...
https://en.wikipedia.org/wiki/Thermogenin
Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cellsTargeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells
The HIV-1 encoded apoptogenic protein Vpr induces mitochondrial membrane permeabilization (MMP) via interactions with the voltage-dependent anion channel (VDAC) and the adenine nucleotide translocator (ANT). We have designed a peptide, TEAM-VP, composed of two functional domains, one a tumor blood v …
https://pubmed.ncbi.nlm.nih.gov/16888644/
AINTEGUMENTA and AINTEGUMENTA-LIKE6 Act Redundantly to Regulate Arabidopsis Floral Growth and Patterning | Plant PhysiologyAINTEGUMENTA and AINTEGUMENTA-LIKE6 Act Redundantly to Regulate Arabidopsis Floral Growth and Patterning | Plant Physiology
Figure 3. The expression patterns of AP3 and AG are altered in ant-4 ail6-2 flowers. A, RNA gel blot of AP3 mRNA in Ler, ant-4, ail6-2, and ant-4 ail6-2 inflorescences. Ethidium bromide staining of ribosomal RNA is shown below the gel blot. B, AP3 expression in stage 3 Ler flower. C and D, AP3 is expressed in fewer cells of stage 3 ant-4 ail6-2 flowers. E, AP3 expression in stage 10 Ler flower. F, AP3 mRNA was detected at the base of some floral organs in this ant-4 ail6-2 flower. G, RNA gel blot of AG mRNA in Ler, ant-4, ail6-2, and ant-4 ail6-2 inflorescences. Ethidium bromide staining of ribosomal RNA is shown below the gel blot. H, AG expression in stage 3 Ler flower. Arrows point to the outer boundary of AG expression. I and J, AG expression in stage 3 (I) and stage 4 (J) ant-4 ail6-2 flowers. Arrows point to the outer boundary of AG expression. AG mRNA is not detected in the very central cells of the floral meristem. K, AG expression in stage 7 Ler flower. L, AG expression is detected in ...
http://www.plantphysiol.org/content/150/4/1916/tab-figures-data
Modeling of ATP-ADP steady-state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria -...Modeling of ATP-ADP steady-state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria -...
A computational model for the ATP-ADP steady-state exchange rate mediated by adenine nucleotide translocase (ANT) versus mitochondrial membrane potential dependence in isolated rat liver mitochondria is presented. The model represents the system of three ordinary differential equations, and the basic components included are ANT,...
http://scipeople.ru/publication/67177/
The biology of mitochondrial uncoupling proteinsThe biology of mitochondrial uncoupling proteins
Uncoupling proteins (UCPs) are mitochondrial transporters present in the inner membrane of mitochondria. They are found in all mammals and in plants. They belong to the family of anion mitochondrial carriers including adenine nucleotide transporters. The term uncoupling protein was originally used …
https://pubmed.ncbi.nlm.nih.gov/14749278/
ANT1 - Peroxisomal adenine nucleotide transporter 1 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast) -...ANT1 - Peroxisomal adenine nucleotide transporter 1 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast) -...
Adenine nucleotide transporter involved in the uniport of ATP and adenine nucleotide hetero-exchange transport between the cytosol and the peroxisomal lumen. This transport is accompanied by a proton transport from the peroxisomal lumen to the cytosol. Transport of ATP into the peroxisome is required for beta-oxidation of medium-chain fatty acids. Required for growth on medium-chain fatty acids, pH gradient formation in peroxisomes and for normal peroxisome proliferation.
http://www.uniprot.org/uniprot/Q06497
Acute Knockdown of Uncoupling Protein-2 Increases Uncoupling via the Adenine Nucleotide Transporter and Decreases Oxidative...Acute Knockdown of Uncoupling Protein-2 Increases Uncoupling via the Adenine Nucleotide Transporter and Decreases Oxidative...
Increased O(2) metabolism resulting in chronic hypoxia is common in models of endstage renal disease. Mitochondrial uncoupling increases O(2) consumption but the ensuing reduction in mitochondrial membrane potential may limit excessive oxidative stress. The present study addressed the hypothesis that mitochondrial uncoupling regulates mitochondria function and oxidative stress in the diabetic kidney. Isolated mitochondria from kidney cortex of control and streptozotocin-induced diabetic rats were studied before and after siRNA knockdown of uncoupling protein-2 (UCP-2). Diabetes resulted in increased UCP-2 protein expression and UCP-2-mediated uncoupling, but normal mitochondria membrane potential. This uncoupling was inhibited by GDP, which also increased the membrane potential. siRNA reduced UCP-2 protein expression in controls and diabetics (-30-50%), but paradoxically further increased uncoupling and markedly reduced the membrane potential. This siRNA mediated uncoupling was unaffected by GDP ...
http://www.diva-portal.org/smash/record.jsf?pid=diva2:540966
We have beforehand claimed that glutamate and the adenine nucleotide translocase inhibitor, carboxyatractyloside, ameliorate...We have beforehand claimed that glutamate and the adenine nucleotide translocase inhibitor, carboxyatractyloside, ameliorate...
OXPHOS - Adenine Nucleotide Assays and IssuesOXPHOS - Adenine Nucleotide Assays and Issues
OXPHOS - this site is dedicated to mitochondria research. Theoretical and practical aspects, reagents, protocols, tools, funding agencies, databases, conferences, etc.
http://oxphos.net/index.php?option=com_content&task=view&id=93&Itemid=1
Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD...Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD...
Background: Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder associated with the partial deletion of integral numbers of 3.3 kb D4Z4 DNA repeats within the subtelomere of chromosome 4q. A number of candidate FSHD genes, adenine nucleotide translocator 1 gene (ANT1), FSHD-related gene 1 (FRG1), FRG2 and DUX4c, upstream of the D4Z4 array (FSHD locus), and double homeobox chromosome 4 (DUX4) within the repeat itself, are upregulated in some patients, thus suggesting an underlying perturbation of the chromatin structure. Furthermore, a mouse model overexpressing FRG1 has been generated, displaying skeletal muscle defects. Results: In the context of myogenic differentiation, we compared the chromatin structure and tridimensional interaction of the D4Z4 array and FRG1 gene promoter, and FRG1 expression, in control and FSHD cells. The FRG1 gene was prematurely expressed during FSHD myoblast differentiation, thus suggesting that the number of D4Z4 repeats in ...
https://epub.ub.uni-muenchen.de/23590/
Starvation-Survival Patterns of Sixteen Freshly Isolated Open-Ocean Bacteria | Applied and Environmental MicrobiologyStarvation-Survival Patterns of Sixteen Freshly Isolated Open-Ocean Bacteria | Applied and Environmental Microbiology
Sixteen marine isolates from a NORPAX cruise, which were transferred once on medium after initial isolation, survived nutrient deprivation for at least 8 months (longest period test). All but one isolate remained cellularly intact, although their sizes and shapes changed greatly, and all became smaller, decreasing in size from 40 to 79%. Three starvation-survival patterns were demonstrated, namely (i) an initial increase in viable cells followed by a decrease until a constant number was reached, (ii) an increase in viable cells until a constant number was reached, and (iii) a decrease in viable cells until a constant number was reached. One isolate from each starvation-survival pattern was starved for 8 months and then was tested in comparison with 4-month-starved Ant-300 for [14C]glutamic acid uptake, respiration, and incorporation. The response to glutamic acid was rapid and linear in each case. The data indicate that the starvation-survival of Ant-300 is not an anomalous situation and that ...
https://aem.asm.org/content/45/3/1109?ijkey=ea4b42a4b7d0e92dff518a5e90e3409184fca8db&keytype2=tf_ipsecsha
Adenine - Drugs.comAdenine - Drugs.com
Adenine is a medicine available in a number of countries worldwide. A list of US medications equivalent to Adenine is available on the Drugs.com website.
https://www.drugs.com/international/adenine.html
Nitroalkenes confer acute cardioprotection via adenine nucleotide translocase<...Nitroalkenes confer acute cardioprotection via adenine nucleotide translocase<...
TY - JOUR. T1 - Nitroalkenes confer acute cardioprotection via adenine nucleotide translocase. AU - Nadtochiy, Sergiy M.. AU - Zhu, Qiuyu. AU - Urciuoli, William. AU - Rafikov, Ruslan. AU - Black, Stephen M.. AU - Brookes, Paul S.. N1 - Copyright: Copyright 2012 Elsevier B.V., All rights reserved.. PY - 2012/1/27. Y1 - 2012/1/27. N2 - Electrophilic nitrated lipids (nitroalkenes) are emerging as an important class of protective cardiovascular signaling molecules. Although species such as nitro-linoleate (LNO 2) and nitro-oleate can confer acute protection against cardiac ischemic injury, their mechanism of action is unclear. Mild uncoupling of mitochondria is known to be cardioprotective, and adenine nucleotide translocase 1 (ANT1) is a key mediator of mitochondrial uncoupling. ANT1 also contains redox-sensitive cysteines that may be targets for modification by nitroalkenes. Therefore, in this study we tested the hypothesis that nitroalkenes directly modify ANT1 and that nitroalkene-mediated ...
https://augusta.pure.elsevier.com/en/publications/nitroalkenes-confer-acute-cardioprotection-via-adenine-nucleotide
Vesicular nucleotide transporter (VNUT): appearance of an actress on the stage of purinergic signaling<...Vesicular nucleotide transporter (VNUT): appearance of an actress on the stage of purinergic signaling<...
TY - JOUR. T1 - Vesicular nucleotide transporter (VNUT). T2 - appearance of an actress on the stage of purinergic signaling. AU - Moriyama, Yoshinori. AU - Hiasa, Miki. AU - Sakamoto, Shohei. AU - Omote, Hiroshi. AU - Nomura, Masatoshi. PY - 2017/9/1. Y1 - 2017/9/1. N2 - Vesicular storage of ATP is one of the processes initiating purinergic chemical transmission. Although an active transport mechanism was postulated to be involved in the processes, a transporter(s) responsible for the vesicular storage of ATP remained unidentified for some time. In 2008, SLC17A9, the last identified member of the solute carrier 17 type I inorganic phosphate transporter family, was found to encode the vesicular nucleotide transporter (VNUT) that is responsible for the vesicular storage of ATP. VNUT transports various nucleotides in a membrane potential-dependent fashion and is expressed in the various ATP-secreting cells. Mice with knockout of the VNUT gene lose vesicular storage and release of ATP from neurons ...
https://kyushu-u.pure.elsevier.com/en/publications/vesicular-nucleotide-transporter-vnut-appearance-of-an-actress-on
Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2...Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2...
AIMS: In this study we investigated whether attenuation of endoplasmic reticulum stress (ER stress) could protect HepG2 cells from free fatty acid (FFA)-induced apoptosis. MAIN METHODS: Human liver cell line HepG2 cells were exposed to Sodium Palmitate (Pa) or Sodium Oleate (Ol). Apoptosis and ER stress of HepG2 cells were analyzed with flow cytometry, real-time RT-PCR and Western Blotting. An expression plasmid encoding for the ER chaperone immunoglobulin heavy chain-binding protein (Bip) was transfected into HepG2 cells to attenuate ER stress. Small interfering RNA siCHOP was used to knockdown the expression of C/EBP Homologous Protein (CHOP) in HepG2. KEY FINDINGS: Pa led to cytotoxicity and apoptosis in HepG2 cells in a dose-dependent pattern and also induced ER stress indicated by increased phosphorylation of eIF2alpha, upregulation of IRE1alpha and CHOP. Bip expression levels were slightly down regulated after Pa treatment. The unsaturated fatty acid, Ol, induced neither apoptosis nor ER stress in
https://www.garvan.org.au/research/publications/10884
Multiple Deletions in Logistic Regression Models | Korea ScienceMultiple Deletions in Logistic Regression Models | Korea Science
Multiple Deletions in Logistic Regression Models - Conditional deletions;logistic regression models;masking effects;multiple deletions;outliers;swamping effects;
http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=GCGHC8_2009_v16n2_309
Ad5-CMV-Ant2 | Seven Hills BioreagentsAd5-CMV-Ant2 | Seven Hills Bioreagents
Vector ConstructionMouse cDNA for the adenine nucleotide translocase 2 (inner mitochondrial membrane transporter). It was cloned into the multiple cloning site of pAC-CMV-pLpA. The resulting plasmid was cotransfected into HEK293 cells with plasmid pJM17 which contains the Ad5 genome. Homologous recombination between the two plasmids resulted in the replacement of the Ad5 early region 1 with the mouse cDNA for Ant2, generating a replication deficient recombinant virus. ...
https://www.sevenhillsbioreagents.com/products/ad5-cmv-ant2
Hepatic Adenine Nucleotides and DNA Synthesis during the Regenerative and Atrophic Process of the Liver Lobes after Selective...Hepatic Adenine Nucleotides and DNA Synthesis during the Regenerative and Atrophic Process of the Liver Lobes after Selective...
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http://www.ndsl.kr/ndsl/search/detail/article/articleSearchResultDetail.do?cn=NART00001059
Fatty-acid-induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is...Fatty-acid-induced activation of NADPH oxidase in plasma membranes of human neutrophils depends on neutrophil cytosol and is...
Both cis and trans unsaturated fatty acids and sodium dodecyl sulfate activated NADPH oxidase in plasma membranes of human neutrophils in the presence of neutrophil cytosol. In contrast, 5,8,11,14-icosatetraynoic acid, saturated fatty acids, esters, peroxides and 4 beta-phorbol 12-myristate 13-acetate, a potent activator of protein kinase C, were inactive. 5,8,11,14-icosatetraynoic acid inhibited superoxide formation elicited by fatty acids. Guanosine 5[gamma-thio]triphosphate (GTP[gamma S]), a potent activator of guanine-nucleotide-binding proteins (N-proteins) enhanced superoxide formation elicited by fatty acids up to fourfold, supporting our previous suggestion that NADPH oxidase is regulated by an N-protein [Seifert, R. et al. (1986) FEBS Lett. 205, 161-165]. Cytosols from various tissues, soybean lipoxygenase and protein kinase C, purified from chicken stomach, did not substitute neutrophil cytosol. The activity of neutrophil cytosol was destroyed by heating at 95 degrees C. Superoxide ...
https://epub.uni-regensburg.de/23273/
Oxidative Phosphorylation Diseases | The Online Metabolic and Molecular Bases of Inherited Disease | OMMBID | McGraw-Hill...Oxidative Phosphorylation Diseases | The Online Metabolic and Molecular Bases of Inherited Disease | OMMBID | McGraw-Hill...
Oxidative phosphorylation (OXPHOS) is composed of five intramitochondrial enzyme complexes (complexes I to V) that are responsible for producing the majority of the ATP required for normal cellular function. Assembly and maintenance of OXPHOS requires the coordinate regulation of nuclear DNA and mitochondrial DNA (mtDNA) genes. The mtDNA encodes 12 OXPHOS subunits, 22 tRNAs, and 2 rRNAs, which provide the core elements for OXPHOS function and mitochondrial protein synthesis. The nuclear DNA is responsible for synthesizing approximately 70 OXPHOS subunits, transporting them to the mitochondria via chaperone proteins, ensuring their passage across the mitochondrial inner membrane, and coordinating their proper processing and assembly. OXPHOS is regulated by a wide variety of factors and processes that include hormone levels, oxygen supply, ion gradients, membrane transporters such as the adenine nucleotide translocase that supplies ADP for conversion to ATP, transcription factors that alter the ...
http://ommbid.mhmedical.com/content.aspx?bookid=971§ionid=62634554
Author: Suyama, Masaki / Subject: adenosine triphosphate - PubAg Search ResultsAuthor: Suyama, Masaki / Subject: adenosine triphosphate - PubAg Search Results
Bongkrekic acid (BKA) is a strong inhibitor of adenine nucleotide translocase (ANT), inducing inhibition of adenosine triphosphate synthesis. We designed and synthesized simplified benzene-ring-containing BKA analogs. The key reaction is the one-pot double Sonogashira reaction, which forms the main skeleton. The analogs were efficiently synthesized in 8-10 longest linear sequence steps. This synth ...
https://pubag.nal.usda.gov/?f%5Bsubject_term%5D%5B%5D=adenosine+triphosphate&q=%22Suyama%2C+Masaki%22&search_field=author
The effect of calcium on the translocation of adenine nucleotides in rat liver mitochondria. - Semantic ScholarThe effect of calcium on the translocation of adenine nucleotides in rat liver mitochondria. - Semantic Scholar
Semantic Scholar extracted view of The effect of calcium on the translocation of adenine nucleotides in rat liver mitochondria. by Armando Gómez-Puyou et al.
https://www.semanticscholar.org/paper/The-effect-of-calcium-on-the-translocation-of-aden-G%C3%B3mez-Puyou-G%C3%B3mez-Puyou/e29c56ebdeab09f6f095d1349f1988c39dcca0ce
TWINKLE TWINKLE PATRICK STAR Lyrics - SPONGEBOB SQUAREPANTS | eLyrics.netTWINKLE TWINKLE PATRICK STAR Lyrics - SPONGEBOB SQUAREPANTS | eLyrics.net
Spongebob Squarepants Twinkle Twinkle Patrick Star lyrics & video : Twinkle Twinkle Patrick Star And I made myself a sandwich My mommy named it Fred It tastes like beans and ba...
https://www.elyrics.net/read/s/spongebob-squarepants-lyrics/twinkle-twinkle-patrick-star-lyrics.html
Associated Effluxes of Calcium and Adenine Nucleotides from Mitochondria: Mediation by Thyroxine and other Agents, and...Associated Effluxes of Calcium and Adenine Nucleotides from Mitochondria: Mediation by Thyroxine and other Agents, and...
Thank you for your interest in spreading the word about Biochemical Society Transactions.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
http://www.biochemsoctrans.org/content/7/1/215
Its Me !!: Twinkle Totz Set Tupperware bayiIts Me !!: Twinkle Totz Set Tupperware bayi
nota :: selalu kalah kalau dalam membeli barangan bayi. Ni pun tengah menunggu 2 parcel lagi barangan bayi. Will show show later ...
http://fizyanz.blogspot.com/2013/04/twinkle-totz-set-tupperware-bayi.html
Glycerophosphoglycerophosphoglycerols (Cardiolipins) - Glycerophospholipids | Sigma-AldrichGlycerophosphoglycerophosphoglycerols (Cardiolipins) - Glycerophospholipids | Sigma-Aldrich
Cardiolipin is found predominantly in the membranes of mitochondria and bacteria. It is a unique diphosphatidylglycerol containing four acyl groups. In animal tissues 80% of the acyl groups are composed of linoleic acid (18:2(n-6)).The identification of Barth′s syndrome, a disease associated with abnormalities in the fatty acid composition of cardiolipin causing cardiomyopathy and neutropenia, has displayed the importance of cardiolipin in mitochondrial functionality. Cardiolipin effects mitochondrial bioenergetics by providing essential structural and functional support to proteins localized within the mitochondria. Specifically, interaction of cardiolipin with cytochrome oxidase and adenine nucleotide translocase is required in order for both of these mitochondrial enzymes to maintain activity.Cardiolipin has been shown to perform a role in a number of other specific biological activities, including oxidative phosphorylation, apoptosis, cholesterol translocation and gene
https://www.sigmaaldrich.com/life-science/biochemicals/biochemical-products.html?TablePage=15845151
Adenine nucleotides in snail muscles as one of biomarkers of fluoride toxicity - Journal of Environmental Monitoring (RSC...Adenine nucleotides in snail muscles as one of biomarkers of fluoride toxicity - Journal of Environmental Monitoring (RSC...
The aim of this work was to determine the extent of bioaccumulation of fluorides in tissues of Helix aspersa maxima. The toxicity of fluorides administered orally on the energy balance of the snails foot was investigated based on measurements of concentrations of adenine nucleotides and their metabolism deg
http://pubs.rsc.org/en/Content/ArticleLanding/EM/2005/B415833B
High-energy phosphates and related adenine nucleotides. | Open-iHigh-energy phosphates and related adenine nucleotides. | Open-i
High-energy phosphates and related adenine nucleotides.Metabolites were measured by HPLC in Control, SHF and DHF hearts. A-C. Chromatograms of extracts from ven
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4366225_pone.0118974.g003&req=4
HIV-1 p24 Antibody | Anti HIV1 p24 Monoclonal | ProSpecHIV-1 p24 Antibody | Anti HIV1 p24 Monoclonal | ProSpec
Mouse Monoclonal antibodies against HIV-1 full length recombinant p24. Captures the p24 antigen. May be paired with mAbs catalog numbers ant-748.
https://www.prospecbio.com/hiv1_p24_antibody
Twinkle Twinkle Little Star - interactive songs | Apps | 148AppsTwinkle Twinkle Little Star - interactive songs | Apps | 148Apps
~~ 9 educational activities & games inside + a full interactive Twinkle Twinkle song ~~ ~~ More than 2,000,000 downloads, Selected New and Noteworthy by...
http://www.148apps.com/app/439929489/
A man ninety years old was asked to what he attributed his longevity. I reckon, he said, with a twinkle in his eye, it because...A man ninety years old was asked to what he attributed his longevity. I reckon, he said, with a twinkle in his eye, it because...
A man ninety years old was asked to what he attributed his longevity. I reckon, he said, with a twinkle in his eye, it because most nights I went to bed and slept when I should have sat up and worried. - Garson Kanin quotes from BrainyQuote.com
https://www.brainyquote.com/quotes/garson_kanin_119545
Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation | Biochemical...Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation | Biochemical...
Adenine nucleotides (AdNs) play important roles in immunity and inflammation. Extracellular AdNs, such as adenosine triphosphate (ATP) or nicotinamide adenine dinucleotide (NAD) and their metabolites, act as paracrine messengers by fine-tuning both pro- and anti-inflammatory processes. Moreover, intracellular AdNs derived from ATP or NAD play important roles in many cells of the immune system, including T lymphocytes, macrophages, neutrophils and others. These intracellular AdNs are signaling molecules that transduce incoming signals into meaningful cellular responses, e.g. activation of immune responses against pathogens. ...
https://portlandpress.com/biochemsoctrans/article-abstract/47/1/329/134/Adenine-nucleotides-as-paracrine-mediators-and?redirectedFrom=fulltext
Battlecode 2014 SoftwareBattlecode 2014 Software
Update to Eclipse 3.5 or higher if you have not done so already. After you have installed the software, open Eclipse and choose File -, New -, Project... and choose Java Project from Existing Ant Buildfile. Navigate to the build.xml in your install folder and use this one. Name your project, or leave it as the default and click Link to build file in the filesystem and click Finish. Alternatively, you can use Java Project from Existing Source and then in the import screen click the (+) next to teams. When it finishes, Eclipse will add the teams folder as a source folder and add the included jar files to your build path. (If you installed Ant, youll see a lots of files beginning with ant- on your build path. You can safely remove them from your build path, but dont delete them!) You can begin developing a player. When youre ready to run a match, right click the build.xml file in your project root directory and choose Run As -, Ant Build. You can re-run the match software ...
http://s3.amazonaws.com/battlecode-releases-2014/docs/software.html
Rose Twinkle #3Rose Twinkle #3
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Bcl-2-associated X proteinBcl-2-associated X protein
"Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis". Science. 281 (5385): 2027-31. ... In addition, it can become activated by binding BCL-2, as well as non-BCL-2 proteins such as p53 and Bif-1. Conversely, BAX can ... Weng C, Li Y, Xu D, Shi Y, Tang H (March 2005). "Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related ... 307 (1): 70-5. doi:10.1016/S0003-2697(02)00028-3. PMID 12137781. Gillissen B, Essmann F, Graupner V, Stärck L, Radetzki S, ...
https://en.wikipedia.org/wiki/Bcl-2-associated_X_protein
BCL2L13BCL2L13
Kim JY, So KJ, Lee S, Park JH (Sep 2012). "Bcl-rambo induces apoptosis via interaction with the adenine nucleotide translocator ... Bcl-rambo mediates apoptosis by associating with adenine nucleotide translocator (ANT), a component of the mitochondrial ... 34 (1): 18-23. doi:10.1016/j.leukres.2009.07.023. PMID 20109966. Jensen SA, Calvert AE, Volpert G, Kouri FM, Hurley LA, Luciano ... 534 (1-3): 61-8. doi:10.1016/S0014-5793(02)03778-X. PMID 12527362. S2CID 7018829. Human BCL2L13 genome location and BCL2L13 ...
https://en.wikipedia.org/wiki/BCL2L13
Sengers syndromeSengers syndrome
AGK gene encodes the mitochondrial acylglycerol kinase which plays a role in the assembly of adenine nucleotide translocator. ... The SLC25A4 gene encodes the heart and muscle specific isoform 1 of the mitochondrial adenine nucleotide translocator. The ...
https://en.wikipedia.org/wiki/Sengers_syndrome
CYC1CYC1
"Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR ... Nishikimi M, Ohta S, Suzuki H, Tanaka T, Kikkawa F, Tanaka M, Kagawa Y, Ozawa T (April 1988). "Nucleotide sequence of a cDNA ... 200 (1-2): 149-56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. Valnot I, Kassis J, Chretien D, de Lonlay P, Parfait B, ... 19 (2): 400-1. doi:10.1006/geno.1994.1084. PMID 8188279. Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S ( ...
https://en.wikipedia.org/wiki/CYC1
List of MeSH codes (D12.776)List of MeSH codes (D12.776)
... adenine nucleotide translocator 2 MeSH D12.776.575.750.500.300 - adenine nucleotide translocator 3 MeSH D12.776.580.210.175.325 ... adenine nucleotide translocator 1 MeSH D12.776.575.750.500.200 - ... neuregulin-1 See List of MeSH codes (D12.776.476). MeSH D12.776 ... cofilin 1 MeSH D12.776.220.525.212.750 - cofilin 2 MeSH D12.776.220.525.212.875 - destrin MeSH D12.776.220.525.246.500 - actin- ... hiv-1 reverse transcriptase MeSH D12.776.964.970.880.325 - gene products, env MeSH D12.776.964.970.880.325.330 - hiv envelope ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776)
ANT1 (disambiguation)ANT1 (disambiguation)
... adenine nucleotide translocator 1) is the most abundant protein in the inner mitochondrial membrane. It is an enzyme that in ...
https://en.wikipedia.org/wiki/ANT1_(disambiguation)
List of MeSH codes (D12.776.157)List of MeSH codes (D12.776.157)
... adenine nucleotide translocator 2 MeSH D12.776.157.530.625.875.500.300 - adenine nucleotide translocator 3 MeSH D12.776.157.530 ... adenine nucleotide translocator 1 MeSH D12.776.157.530.625.875.500.200 - ... nucleotide transport proteins MeSH D12.776.157.530.625.875.500 - mitochondrial adp, atp translocases MeSH D12.776.157.530. ... aryl hydrocarbon receptor nuclear translocator MeSH D12.776.157.530.750.200 - cellular apoptosis susceptibility protein MeSH ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.157)
Y linkageY linkage
... adenine nucleotide translocator-3 on the Y), AZF2 (azoospermia factor 2), BPY2 (basic protein on the Y chromosome), AZF1 ( ... family 1, member A1), RBM2 (RNA binding motif protein 2), and UTY (ubiquitously transcribed TPR gene on Y chromosome). USP9Y ... azoospermia factor 1), DAZ (Spermatogenes is deleted in azoospermia), RBM1 (RNA binding motif protein, Y chromosome, ...
https://en.wikipedia.org/wiki/Y_linkage
List of MeSH codes (D12.776.543)List of MeSH codes (D12.776.543)
... adenine nucleotide translocator 2 MeSH D12.776.543.585.450.162.235.300 - adenine nucleotide translocator 3 MeSH D12.776.543.585 ... adenine nucleotide translocator 2 MeSH D12.776.543.585.625.875.500.300 - adenine nucleotide translocator 3 MeSH D12.776.543.585 ... adenine nucleotide translocator 1 MeSH D12.776.543.585.450.162.235.200 - ... adenine nucleotide translocator 1 MeSH D12.776.543.585.625.875.500.200 - ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.543)
Adenine nucleotide translocatorAdenine nucleotide translocator
Adenine+Nucleotide+Translocator+2 at the US National Library of Medicine Medical Subject Headings (MeSH) Adenine+Nucleotide+ ... Adenine nucleotide translocator (ANT), also known as the ADP/ATP translocase (ANT), ADP/ATP carrier protein (AAC) or ... Adenine+Nucleotide+Translocator+1 at the US National Library of Medicine Medical Subject Headings (MeSH) ... Pressman BC (June 1958). "Intramitochondrial nucleotides. I. Some factors affecting net interconversions of adenine nucleotides ...
https://en.wikipedia.org/wiki/Adenine_nucleotide_translocator
ARHGAP11BARHGAP11B
... where it binds to the adenine nucleotide translocator. It does not affect the adenine nucleotide exchange activity of the ... translocator, but it does lead to delayed opening of the mitochondrial permeability transition pore, thus allowing for greater ... In contrast to full-length ARHGAP11A and ARHGAP11A 1-250, ARHGAP11B, like ARHGAP11A1-220, did not exhibit RhoGAP activity in a ...
https://en.wikipedia.org/wiki/ARHGAP11B
ApoptosomeApoptosome
... the inner membrane protein adenine nucleotide translocator (AdNT) and the matrix protein cyclophilin D (CyD) (12). This pore ... It has also been shown that the nucleotide dATP as third component binds to apaf-1, however its exact role is still debated. ... A short linker and nucleotide binding a/b domains (NBD) that contain conserved Walker boxes A (p-loop 155-161) and B (239-243) ... a central nucleotide-binding and oligomerization region (NB-ARC/NOD, 128-586) and a C-terminal WD40 region (613-1248) making up ...
https://en.wikipedia.org/wiki/Apoptosome
MT-TTMT-TT
... myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator". ... MT-TT is a small 66 nucleotide RNA (human mitochondrial map position 15888-15953) that transfers the amino acid threonine to a ... 225 (1): 180-5. doi:10.1006/bbrc.1996.1150. PMID 8769114. This article incorporates text from the United States National ...
https://en.wikipedia.org/wiki/MT-TT
ThermogeninThermogenin
UCP1 is very similar to the ATP/ADP Carrier protein, or Adenine Nucleotide Translocator (ANT). The proposed alternating access ... UCP1 is related to other mitochondrial metabolite transporters such as the adenine nucleotide translocator, a proton channel in ... UCP1 is activated in the brown fat cell by fatty acids and inhibited by nucleotides. Fatty acids are released by the following ... overriding the inhibition caused by purine nucleotides (GDP and ADP). During the termination of thermogenesis, thermogenin is ...
https://en.wikipedia.org/wiki/Thermogenin
TXN2TXN2
... thiols in the mitochondrial permeability transition pore component adenine nucleotide translocator (ANT). Overexpression of ... "Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer". Cancer Research. ... 465 (1): 119-26. doi:10.1016/j.abb.2007.05.001. PMID 17548047. Oestergaard MZ, Tyrer J, Cebrian A, Shah M, Dunning AM, Ponder ... Zhou J, Damdimopoulos AE, Spyrou G, Brüne B (Mar 2007). "Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on ...
https://en.wikipedia.org/wiki/TXN2
Ant (disambiguation)Ant (disambiguation)
Actor-network theory, an approach to social theory and research Adenine nucleotide translocator Anacamptis (abbreviation Ant), ... ISO 3166-1 alpha-3 country code) River Ant, a river in Norfolk, England Ant (name), English language nickname abbreviated from ...
https://en.wikipedia.org/wiki/Ant_(disambiguation)
Substrate-level phosphorylationSubstrate-level phosphorylation
... but also to prevent mitochondria from straining glycolytic ATP reserves by maintaining the adenine nucleotide translocator in ' ... "Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level ... "Expression of two succinyl-CoA synthetases with different nucleotide specificities in mammalian tissues". The Journal of ... 1,3-bisphosphoglycerate is then dephosphorylated via phosphoglycerate kinase, producing 3-phosphoglycerate and ATP through a ...
https://en.wikipedia.org/wiki/Substrate-level_phosphorylation
MitochondrionMitochondrion
ROS increases uncoupling proteins (UCPs) and potentiate proton leakage through the adenine nucleotide translocator (ANT), the ... Nachman MW, Crowell SL (September 2000). "Estimate of the mutation rate per nucleotide in humans". Genetics. 156 (1): 297-304. ... Tumor cells require ample ATP to synthesize bioactive compounds such as lipids, proteins, and nucleotides for rapid ... The VDAC is the primary transporter of nucleotides, ions and metabolites between the cytosol and the intermembrane space. It is ...
https://en.wikipedia.org/wiki/Mitochondrion
Membrane transport proteinMembrane transport protein
Adenine nucleotide translocator (ANT) 2.B: Nonribosomally synthesized porters, such as: The Nigericin family The Ionomycin ... such as rhodopsin The group translocators provide a special mechanism for the phosphorylation of sugars as they are transported ... ISBN 1-4292-1962-9. p. 119. Cooper, Geoffrey (2009). The Cell: A Molecular Approach. Washington, DC: ASM Press. p. 62. ISBN ... ISBN 1-4292-1962-9. p. 119. Ashley, Ruth. Hann, Gary. Han, Seong S. Cell Biology. New Age International Publishers. ISBN ...
https://en.wikipedia.org/wiki/Membrane_transport_protein
Category:Protein pages needing a pictureCategory:Protein pages needing a picture
Adenine nucleotide translocator. *Adenosine deaminase. *Adenosylmethionine decarboxylase. *Adenylosuccinate synthase. *AdoMet ...
https://en.wikipedia.org/wiki/Category:Protein_pages_needing_a_picture
Jerzy Duszyński (biochemist)Jerzy Duszyński (biochemist)
1982). "Quantification of the role of the adenine nucleotide translocator in the control of mitochondrial respiration in ... The first quantification of the controlling weight of adenine nucleotide transport in cellular bioenergetics. Quantification of ... 1 year, including in Grenoble). The course of his scientific career has been closely linked to the Nencki Institute of ...
https://en.wikipedia.org/wiki/Jerzy_Duszyński_(biochemist)
Mitochondrial carrierMitochondrial carrier
SLC25A25 adenine nucleotide - SLC25A4, SLC25A5, SLC25A6, SLC25A31 dicarboxylate - SLC25A10 oxoglutarate - SLC25A11 glutamate - ... "Site-directed mutagenesis of the yeast mitochondrial ADP/ATP translocator. Six arginines and one lysine are essential". Journal ... Mitochondrial carriers transport amino acids, keto acids, nucleotides, inorganic ions and co-factors through the mitochondrial ... nucleotides, amino acids, keto acids and cofactors across the membrane. Such proteins include: ADP/ATP carrier protein (ADP-ATP ...
https://en.wikipedia.org/wiki/Mitochondrial_carrier
Mitochondrial permeability transition poreMitochondrial permeability transition pore
Further hypothesis by Halestrap's group convincingly suggested the MPT was formed by the inner membrane Adenine Nucleotide ... "The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore". Nature. 427 (6973): 461-465. doi ... "The nature of the calcium ion efflux induced in rat liver mitochondria by the oxidation of endogenous nicotinamide nucleotides ... "Regulation of the Inner Membrane Mitochondrial Permeability Transition by the Outer Membrane Translocator Protein (Peripheral ...
https://en.wikipedia.org/wiki/Mitochondrial_permeability_transition_pore
Substrate-level phosphorylationSubstrate-level phosphorylation
... but also to prevent mitochondria from straining glycolytic ATP reserves by maintaining the adenine nucleotide translocator in ' ... "Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level ... "Expression of two succinyl-CoA synthetases with different nucleotide specificities in mammalian tissues". The Journal of ... 1,3-bisphosphoglycerate is then dephosphorylated via phosphoglycerate kinase, producing 3-phosphoglycerate and ATP through a ...
https://en.m.wikipedia.org/wiki/Substrate-level_phosphorylation
Adenine Nucleotide Translocator 1 Summary Report | CureHunterAdenine Nucleotide Translocator 1 Summary Report | CureHunter
Adenine Nucleotide Translocator 1: A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM ... Adenine Nucleotide Carrier Protein; Adenine Nucleotide Translocator, Muscle Isoform; SLC25A4 Protein; Solute Carrier Family 25( ... Nucleotide Transport Proteins*ATP Translocases Mitochondrial ADP: 95*Adenine Nucleotide Translocator 1: 14 ... Nucleotide Transport Proteins*ATP Translocases Mitochondrial ADP: 95*Adenine Nucleotide Translocator 1: 14 ...
http://www.curehunter.com/public/keywordSummaryD033741-Adenine-Nucleotide-Translocator-1.do
Adenine nucleotide translocator 1 | definition of adenine nucleotide translocator 1 by Medical dictionaryAdenine nucleotide translocator 1 | definition of adenine nucleotide translocator 1 by Medical dictionary
What is adenine nucleotide translocator 1? Meaning of adenine nucleotide translocator 1 medical term. What does adenine ... Looking for online definition of adenine nucleotide translocator 1 in the Medical Dictionary? adenine nucleotide translocator 1 ... redirected from adenine nucleotide translocator 1) SLC25A4. A gene on chromosome 4q35 that encodes a mitochondrial solute ... adenine nucleotide translocator 2. *Adenine Nucleotide Translocator Isoform Transcription Pattern. *Adenine Nucleotide ...
https://medical-dictionary.thefreedictionary.com/adenine+nucleotide+translocator+1
TGF-β1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors |...TGF-β1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors |...
The adenine nucleotide translocator 1 (Ant1) is an inner mitochondrial membrane protein involved with energy mobilization ... The adenine nucleotide translocator 1 (Ant1) is an inner mitochondrial membrane protein involved with energy mobilization ... Buck CR, Jurynec MJ, Gupta DK, Law AK, Bilger J, Wallace DC, McKeon RJ: Increased adenine nucleotide translocator 1 in reactive ... Luciakova K, Hodny Z, Barath P, Nelson BD: In vivo mapping of the human adenine nucleotide translocator-2 (ANT2) promoter ...
https://bmcneurosci.biomedcentral.com/articles/10.1186/1471-2202-5-1
Adenine nucleotide translocator - definition of Adenine nucleotide translocator by The Free DictionaryAdenine nucleotide translocator - definition of Adenine nucleotide translocator by The Free Dictionary
Adenine nucleotide translocator synonyms, Adenine nucleotide translocator pronunciation, Adenine nucleotide translocator ... English dictionary definition of Adenine nucleotide translocator. n. Abbr. A A purine base, C5H5N5, that is the constituent ... Related to Adenine nucleotide translocator: adenine nucleotide translocator 2. ad·e·nine. (ăd′n-ēn′, -ĭn). n. Abbr. A. A purine ... Adenine nucleotide translocator - definition of Adenine nucleotide translocator by The Free Dictionary https://www. ...
http://www.thefreedictionary.com/Adenine+nucleotide+translocator
Adenine nucleotide translocator - WikipediaAdenine nucleotide translocator - Wikipedia
Adenine+Nucleotide+Translocator+2 at the US National Library of Medicine Medical Subject Headings (MeSH) Adenine+Nucleotide+ ... Adenine nucleotide translocator (ANT), also known as the ADP/ATP translocase (ANT), ADP/ATP carrier protein (AAC) or ... Adenine+Nucleotide+Translocator+1 at the US National Library of Medicine Medical Subject Headings (MeSH) ... Pressman BC (June 1958). "Intramitochondrial nucleotides. I. Some factors affecting net interconversions of adenine nucleotides ...
https://en.wikipedia.org/wiki/Adenine_nucleotide_translocator
JCI - Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease...JCI - Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease...
Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease ... Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease ... of mitochondrial integrity and that in vitro PIs act to prevent pore function of the adenine nucleotide translocator (ANT) ... Published July 1, 2005 Citation Information: J Clin Invest. 2005;115(7):1828-1838. https://doi.org/10.1172/JCI22954. View: Text ...
https://jci.org/articles/view/22954/pdf
Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2...Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2...
Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 ... adenine nucleotide translocator) in the mediation of this UCP1-independent fatty-acid-induced uncoupling in brown-fat ... Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 ... Uncoupling protein 1 inhibition by purine nucleotides is under the control of the endogenous ubiquinone redox state Biochem J ( ...
https://portlandpress.com/biochemj/article-abstract/399/3/405/41792/Carboxyatractyloside-effects-on-brown-fat
Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab192410) | AbcamAnti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab192410) | Abcam
Rabbit polyclonal Adenine Nucleotide Translocator 2/ANT 2 antibody. Validated in WB and tested in Rat, Human. Immunogen ... Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody. See all Adenine Nucleotide Translocator 2/ANT 2 primary antibodies. ... Rabbit Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab192410) WB Protein - Recombinant Human Adenine Nucleotide ... All lanes : Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab192410). Lane 1 : A549 whole cell lysate. Lane 2 : PC12 ...
https://www.abcam.com/adenine-nucleotide-translocator-2ant-2-antibody-ab192410.html
Table of Contents - August 04, 2000, 289 (5480) | ScienceTable of Contents - August 04, 2000, 289 (5480) | Science
Role of Adenine Nucleotide Translocator 1 in mtDNA Maintenance. By Jyrki Kaukonen, Jukka K. Juselius, Valeria Tiranti, Aija ...
http://science.sciencemag.org/content/289/5480
Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab221956) | AbcamAnti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab221956) | Abcam
Rabbit polyclonal Adenine Nucleotide Translocator 2/ANT 2 antibody. Validated in WB, IHC and tested in Human. Independently ... reviewed in 1 review(s). Immunogen corresponding to recombinant fragment. ... Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody. See all Adenine Nucleotide Translocator 2/ANT 2 primary antibodies. ... All lanes : Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab221956) at 1/100 dilution. Lane 1 : RT-4 cell lysate. Lane ...
https://www.abcam.com/adenine-nucleotide-translocator-2ant-2-antibody-ab221956.html
Expression of Adenine Nucleotide Translocator Correlates with the IL-4-induced lymphocyte survival: Role of PI3K and MAPKExpression of Adenine Nucleotide Translocator Correlates with the IL-4-induced lymphocyte survival: Role of PI3K and MAPK
... Ji- ... Ji-Young Jang and Choong-Eun Lee, "Expression of Adenine Nucleotide Translocator Correlates with the IL-4-induced lymphocyte ... Volume 1, Pages 100-100. http://dx.doi.org/10.1100/tsw.2001.193. Short Report ...
https://www.hindawi.com/journals/tswj/2001/841234/cta/
A novel missense adenine nucleotide translocator-1 gene mutation in a greek adPEO family<...A novel missense adenine nucleotide translocator-1 gene mutation in a greek adPEO family<...
A novel missense adenine nucleotide translocator-1 gene mutation in a greek adPEO family. Neurology. 2001 Dec 26;57(12):2295- ... A novel missense adenine nucleotide translocator-1 gene mutation in a greek adPEO family. / Napoli, L.; Bordoni, A.; Zeviani, M ... Fingerprint Dive into the research topics of A novel missense adenine nucleotide translocator-1 gene mutation in a greek adPEO ... A novel missense adenine nucleotide translocator-1 gene mutation in a greek adPEO family. ...
https://moh-it.pure.elsevier.com/en/publications/a-novel-missense-adenine-nucleotide-translocator-1-gene-mutation-
ADP/ATP translocase 3 (P12236) | InterPro | EMBL-EBIADP/ATP translocase 3 (P12236) | InterPro | EMBL-EBI
Adenine nucleotide translocator 1 (IPR002113). Homologous superfamilies. * Homologous superfamily. 1 50 100 150 200 250 298 ...
http://www.ebi.ac.uk/interpro/protein/P12236
SLC25A4 gene: MedlinePlus GeneticsSLC25A4 gene: MedlinePlus Genetics
The SLC25A4 gene provides the instructions for making a protein called adenine nucleotide translocase type 1 (ANT1). Learn ... Severity of cardiomyopathy associated with adenine nucleotide translocator-1 deficiency correlates with mtDNA haplogroup. Proc ... Complete loss-of-function of the heart/muscle-specific adenine nucleotide translocator is associated with mitochondrial ... The adenine nucleotide translocase type 1 (ANT1): a new factor in mitochondrial disease. IUBMB Life. 2005 Sep;57(9):607-14. ...
https://medlineplus.gov/genetics/gene/slc25a4/
Remarkable infidelity of polymerase gammaA associated with mutations in POLG1 exonuclease domainRemarkable infidelity of polymerase gammaA associated with mutations in POLG1 exonuclease domain
Adenine Nucleotide Translocator 1 / genetics * DNA Helicases * DNA Mutational Analysis * DNA Polymerase gamma ... R Del Bo 1 , A Bordoni, M Sciacco, A Di Fonzo, S Galbiati, M Crimi, N Bresolin, G P Comi ... 1 Centro Dino Ferrari, Dipartimento di Scienze Neurologiche, Università degli Studi di Milano, I.R.C.C.S. Ospedale Maggiore ...
https://pubmed.ncbi.nlm.nih.gov/14557557/
Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice. - Science...Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice. - Science...
Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice.. Am J ... and adenine nucleotide translocator 1 (ANT1), have been identified as autoantigens in cardiac autoimmunity. Herein, we ...
https://www.scienceexchange.com/publications/12628
Phosphotransfer networks and cellular energetics | Journal of Experimental BiologyPhosphotransfer networks and cellular energetics | Journal of Experimental Biology
... intracristal space would inhibit export of ATP from the mitochondrial matrix by locking the adenine nucleotide translocator ( ... Following the discovery of adenine nucleotides, and their role in cellular energetics as a key link between spatially separated ... However, energy transfer by diffusional exchange of adenine nucleotides is kinetically and thermodynamically inefficient since ... was among the first to notice the analogy between the energy-carrying adenine nucleotide system and the electrical circuit. ...
https://jeb.biologists.org/content/206/12/2039
Similar articles for PubMed (Select 11756613) - PubMed - NCBISimilar articles for PubMed (Select 11756613) - PubMed - NCBI
Role of adenine nucleotide translocator 1 in mtDNA maintenance.. Kaukonen J, Juselius JK, Tiranti V, Kyttälä A, Zeviani M, Comi ... A novel missense adenine nucleotide translocator-1 gene mutation in a Greek adPEO family. ... Adeno-associated virus-mediated gene transfer of the heart/muscle adenine nucleotide translocator (ANT) in mouse. ... A novel D104G mutation in the adenine nucleotide translocator 1 gene in autosomal dominant progressive external ophthalmoplegia ...
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IUCr) T-to-R switch of muscle fructose-1,6-bis-phosphatase involves fundamental changes of secondary and quaternary structureIUCr) T-to-R switch of muscle fructose-1,6-bis-phosphatase involves fundamental changes of secondary and quaternary structure
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SLC25A5 - ADP/ATP translocase 2 - Homo sapiens (Human) - SLC25A5 gene & proteinSLC25A5 - ADP/ATP translocase 2 - Homo sapiens (Human) - SLC25A5 gene & protein
"The human fibroblast adenine nucleotide translocator gene. Molecular cloning and sequence.". Ku D.-H., Kagan J., Chen S.-T., ... "The human fibroblast adenine nucleotide translocator gene. Molecular cloning and sequence.". Ku D.-H., Kagan J., Chen S.-T., ... "The human fibroblast adenine nucleotide translocator gene. Molecular cloning and sequence.". Ku D.-H., Kagan J., Chen S.-T., ... adenine nucleotide transport Source: UniProtKBInferred from mutant phenotypei*. "Capsaicin binds to prohibitin 2 and displaces ...
https://www.uniprot.org/uniprot/P05141
Distinct Effects of Saturated and Monounsaturated Fatty Acids on β-Cell Turnover and Function | DiabetesDistinct Effects of Saturated and Monounsaturated Fatty Acids on β-Cell Turnover and Function | Diabetes
ANT, adenine nucleotide translocator; BSA, bovine serum albumin; PBS, phosphate-buffered saline; TUNEL, terminal ... Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281: 2027 -2031, 1998. ... the adenine nucleotide translocator (ANT) (15). ANT catalyses the exchange of ADP and ATP across the inner mitochondrial ... palmitic acid but not palmitoleic acid decreased the expression of the mitochondrial adenine nucleotide translocator and ...
http://diabetes.diabetesjournals.org/content/50/1/69.long
Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome | Clinical ScienceMolecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome | Clinical Science
Abbreviations: ANT, adenine nucleotide translocator; BMI, body mass index; MPTP, mitochondrial permeability transition pore; ... PGC-1α, PPARγ co-activator 1α; ROS, reactive oxygen species; SERCA2a, sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2a; SOD, ...
http://www.clinsci.org/content/114/3/195
Adenine Nucleotide Translocase 1 Antibody (NBP1-59594): Novus BiologicalsAdenine Nucleotide Translocase 1 Antibody (NBP1-59594): Novus Biologicals
Rabbit Polyclonal Anti-Adenine Nucleotide Translocase 1 Antibody. Validated: WB, ICC/IF, IHC, IHC-P. Tested Reactivity: Human, ... Synthetic peptides corresponding to SLC25A4 (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator ... Check out the latest blog posts on Adenine Nucleotide Translocase 1.. New Players in the Mitophagy Game. By Christina Towers, ... FAQs for Adenine Nucleotide Translocase 1 Antibody (NBP1-59594) (0). There are no specific FAQs related to this product. Read ...
https://www.novusbio.com/products/adenine-nucleotide-translocase-1-antibody_nbp1-59594
KEGG BRITE: KEGG Orthology (KO) - Oryza sativa japonica (Japanese rice) (RAPDB)KEGG BRITE: KEGG Orthology (KO) - Oryza sativa japonica (Japanese rice) (RAPDB)
Os11t0432400-01 Os11g0432400; Similar to 2-oxoglutarate/malate translocator. Os09t0465400-00 Os09g0465400; Adenine nucleotide ... Os03t0292200-01 Os03g0292200; Adenine nucleotide translocator 1 domain containing protein. Os09t0454600-00 Os09g0454600; ... Os05t0357200-01 Os05g0357200; Adenine nucleotide translocator 1 domain containing protein. Os03t0734700-01 Os03g0734700; ... Os08t0386800-01 Os08g0386800; Adenine nucleotide translocator 1 domain containing protein. Os09t0444700-01 Os09g0444700; ...
https://www.genome.jp/kegg-bin/get_htext?dosa00001+Os09t0286400-01
SLC25A6P1 Gene - GeneCards | SLC25A6P1 PseudogeneSLC25A6P1 Gene - GeneCards | SLC25A6P1 Pseudogene
Solute Carrier Family 25 Member 6 Pseudogene 1, including: function, proteins, disorders, pathways, orthologs, and expression. ... Adenine Nucleotide Translocator), Member 6 Pseudogene 3 * Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide ... Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide Translocator), Member 6, Pseudogene 1 2 3 ... The GeneCards human gene database index: 1 2 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=SLC25A6P1
Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma | JEMGankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma | JEM
adenine nucleotide translocator. ARE. antioxidant-response element. GCLC. glutamate-cysteine ligase, catalytic subunit. GCLM. ... adenine nucleotide translocator (ANT; the key indicator of nitrative stress); catalase (CAT); glutamate-cysteine ligase, ... Further evidence supporting the protective role of Nrf2 comes from studies of mice or humans harboring a single-nucleotide ... HO-1. heme oxygenase 1. NAC. N-acetyl cysteine. NQO1. NAD(P)H:quinone oxidoreductase l. ROS. reactive oxygen species. SOD. ...
http://jem.rupress.org/content/213/5/859
Measurement of the energy-generating capacity of human muscle mitochondria: diagnostic procedure and application to human...Measurement of the energy-generating capacity of human muscle mitochondria: diagnostic procedure and application to human...
Deficiency of the adenine nucleotide translocator in muscle of a patient with myopathy and lactic acidosis: a new mitochondrial ... The adenine nucleotide translocator (ANT) transports ATP out of the mitochondrion. Deficiencies have been found in all OXPHOS ... adenine nucleotide translocator; mtDNA, mitochondrial DNA; CCCP, carbonyl cyanide 3-chlorophenyl hydrazone; CS, citrate ... 1-[sup.14]C]Sodium pyruvate (0.4-1.1 GBq/mmol) and L-[1,4(2,3)-[sup.14]C]malate ([U-[sup.14]C]malate; 1.5-2.3 GBq/mmol) were ...
https://www.thefreelibrary.com/Measurement+of+the+energy-generating+capacity+of+human+muscle+...-a0209353130
ANT Antibody ANT Antibody
Supplied as 1 mL purified antibody (5 mg/ml) in PBS with 0.09% sodium azide; pH 7.2. ... mitochondrial adenine nucleotide translocator; Slc25a4; solute carrier family 25 (mitochondrial adenine nucleotide translocator ... Protein Aliases: Adenine nucleotide translocator 1; Adenosine translocase; ADP ATP carrier protein 1; ADP ATP translocase; ADP, ... Synthetic peptide, conjugated to KLH, corresponding to residues C G(1) D Q A L S F L K D F(11) of rat Adenosine Nucleotide ...
https://www.thermofisher.com/antibody/product/Adenosine-Nucleotide-Translocator-1-Antibody-Polyclonal/PA1-85116
Oxidative Phosphorylation System: Nuclear Genes and Genetic DiseaseOxidative Phosphorylation System: Nuclear Genes and Genetic Disease
2000) Role of adenine nucleotide translocator 1 in mtDNA maintenance. Science 289 (5480): 782-785. ... Electrons (e−) from carbon oxidations are transferred via NADH (nicotinamide adenine dinucleotide) into OXPHOS complex I, which ... Brain 135 (Pt 1): 12-22.. Ostergaard E, Christensen E, Kristensen E, et al. (2007) Deficiency of the alpha subunit of succinate ... 2008) The Q‐cycle reviewed: how well does a monomeric mechanism of the bc(1) complex account for the function of a dimeric ...
http://www.els.net/WileyCDA/ElsArticle/refId-a0006029.html
TCDB » SEARCHTCDB » SEARCH
... adenine nucleotide translocator 1 (ANT1); adPEO, Sengers syndrome (SLC25A4). Valine 181 is critical for the nucleotide exchange ... Adenine nucleotide transporter, ANT, or ATP:ADP carrier AAC1 (one of three paralogues). Transports heme and heme precursor ... Adenine nucleotide (ATP, ADP) carrier, ANT1; BRITTLE-1. Present in both mitochondria and plastids (Haferkamp and Schmitz-Esser ... The Endoplasmic Reticular Adenine Nucleotide Transporter, ER-ANT1 (probable ATP:ADP exchanger; Leroch et al., 2008) ...
https://tcdb.org/search/result.php?tc=2.A.29.32
ANT1TranslocaseProteinAnti-Adenine Nucleotide TSkeletal muscleMitochondriaSLC25A4AAC1IsoformAntibodyGenesMPTPVDACAdenosineProteinsSolute CarrieMechanistic target of rapamycinMolecularApoptosisNicotinamideTransporterPoreANT2CardiacOxidative phosphorylationPurine basePyruvateExpressionInner mitochonPeptidesPhosphorylationFSHDAbstractPrimary antibodiesInhibitRedoxMetabolismCarrier2001CellularNADH
ANT111
  • The adenine nucleotide translocator 1 (Ant1) is an inner mitochondrial membrane protein involved with energy mobilization during oxidative phosphorylation. (biomedcentral.com)
  • The ANT1 gene encodes the adenine nucleotide translocator-1 (ANT1). (elsevier.com)
  • The SLC25A4 gene provides the instructions for making a protein called adenine nucleotide translocase type 1 (ANT1). (medlineplus.gov)
  • In support of this notion, intracellular cardiac antigens, like cardiac myosin heavy chain-α, cardiac troponin-I, and adenine nucleotide translocator 1 (ANT1), have been identified as autoantigens in cardiac autoimmunity. (scienceexchange.com)
  • The adenine nucleotide translocase type 1 (ANT1): a new factor in mitochondrial disease. (nih.gov)
  • Misfolding of mutant adenine nucleotide translocase in yeast supports a novel mechanism of Ant1-induced muscle diseases. (nih.gov)
  • and ophthalmoplegia with multiple mtDNA deletions, caused by adenine nucleotide translocator-1 (ANT1) mutations. (nih.gov)
  • The article presents the results of image acquisitions obtained from 15 patients, 10 healthy and 5 with the ANT1 (Adenine Nucleotide Translocator-1) mutation, which affects cardiac cycles. (eurekalert.org)
  • Moreover, an overexpression of both sarco/endoplasmic Ca(2+)-ATPase (SERCA1) and adenine nucleotide translocator (ANT1), both factors related to cellular energetic efficiency, was observed. (lu.se)
  • The predominant isoform is the heart-muscle-brain ANT-isoform gene 1 (Ant1) while the other is the systemic Ant2 gene. (escholarship.org)
  • A number of candidate FSHD genes, adenine nucleotide translocator 1 gene (ANT1), FSHD-related gene 1 (FRG1), FRG2 and DUX4c, upstream of the D4Z4 array (FSHD locus), and double homeobox chromosome 4 (DUX4) within the repeat itself, are upregulated in some patients, thus suggesting an underlying perturbation of the chromatin structure. (uni-muenchen.de)
Translocase10
  • Adenine nucleotide translocator (ANT), also known as the ADP/ATP translocase (ANT), ADP/ATP carrier protein (AAC) or mitochondrial ADP/ATP carrier, exchanges free ATP with free ADP across the inner mitochondrial membrane. (wikipedia.org)
  • ADP/ATP translocase 1 is the major AAC in human cells and the archetypal protein of this family. (wikipedia.org)
  • ATP and ADP are the only natural nucleotides recognized by the translocase. (wikipedia.org)
  • Western Blot: Adenine Nucleotide Translocase 1 Antibody [NBP1-59594] - RPMI 8226 cell lysate, concentration 0.2-1 ug/ml. (novusbio.com)
  • Thus, pore opening in the inner mitochondrial membrane results from the binding of Ca 2+ to the adenine nucleotide translocase. (tcdb.org)
  • Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria. (uzh.ch)
  • PubMed ID 15063741) used bongkrekic acid to inhibit mitochondrial adenine nucleotide translocase 3 (ANT3)-mediated apoptosis in cultured cells. (scbt.com)
  • Transgenic overexpression of adenine nucleotide translocase 1 protects ischemic hearts against oxidative stress. (genscript.com)
  • To involvement the conformation of the adenine nucleotide translocase in opening the Tl(+)-induced permeability transition pore in Ca(2+)-loaded rat liver mitochondria. (genscript.com)
  • Adenine nucleotide translocase 1 overexpression protects cardiomyocytes against hypoxia via increased ERK1/2 and AKT activation. (genscript.com)
Protein14
  • The researchers speculate that because the heart cells also produce ANT2, another form of the adenine nucleotide translocator protein, enough ATP gets out to prevent enlargement of the mitochondria. (thefreedictionary.com)
  • In brown-fat mitochondria, fatty acids induce thermogenic uncoupling through activation of UCP1 (uncoupling protein 1). (portlandpress.com)
  • ab192410 detects endogenous levels of Adenine Nucleotide Translocator 2/ANT 2 protein. (abcam.com)
  • Similar to Multidrug resistance protein 1 homolog. (genome.jp)
  • Multidrug resistance associated protein 1. (genome.jp)
  • Human SLC25A4 full-length ORF ( NP_001142.2, 1 a.a. - 298 a.a.) recombinant protein with GST-tag at N-terminal. (abnova.com)
  • Serum myocardial autoantibodies against beta1-adrenoceptor, alpha-myosin heavy chain, M2-muscarinic receptor and adenine-nucleotide translocator were tested, and inflammatory cytokines and high sensitivity C-reaction protein were measured and lymphocyte subclass was assayed by flow cytometry. (springer.com)
  • Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2. (nih.gov)
  • Viral protein R (Vpr), an apoptogenic accessory protein encoded by HIV-1, induces mitochondrial membrane permeabilization (MMP) via a specific interaction with the permeability transition pore complex, which comprises the voltage-dependent anion channel (VDAC) in the outer membrane (OM) and the adenine nucleotide translocator (ANT) in the inner membrane. (nih.gov)
  • By using yeast two-hybrid screening, we also identified a new HIV-1 PR interaction partner, breast carcinoma-associated protein 3 (BCA3). (biomedcentral.com)
  • In summary, our results describe the involvement of HIV-1 PR in apoptosis, which is caused either by a direct effect of HIV-1 PR on mitochondrial membrane integrity or by its interaction with cellular protein BCA3. (biomedcentral.com)
  • Analyzing the expression of some factors related to proteolytic and thermogenic processes, we observed in tumor-bearing animals an increased expression of genes involved in proteolysis such as ubiquitin ligases Muscle Ring Finger 1 (MuRF-1) and Muscle Atrophy F-box protein (MAFBx). (lu.se)
  • There was also significant reduction of activity of citrate synthase and respiratory chain complexes (RCCs) I, II and IV, decreased quantity of oligomycin-sensitivity conferring protein (OSCP) and the E2 subunit of pyruvate dehydrogenase (PDHE2), and differential expression of optic atrophy 1 protein (OPA1) and dynamin-related protein 1 (DRP1) in the skeletal muscle of TgHD minipigs. (biologists.org)
  • HIV-1 viral protein R (Vpr) is a major pro-apoptotic gene product. (pasteur.fr)
Anti-Adenine Nucleotide T2
  • On 0, 1, 2, 3, 4, 6 weeks post injection, frequencies of splenic Tfh cells were determined by flow cytometric analysis, productions of IL-21 and anti-adenine nucleotide translocator(ANT) autoantibody were detected by enzyme-linked immunosorbent assay. (biomedcentral.com)
  • Anti-β1-adrenergic receptor autoantibodies, anti-adenine nucleotide translocator(ANT) autoantibodies and anti-cardiac myosin autoantibodies were common seen in VMC and DCM patients, suggesting the existence of abnormal humoral autoimmune responses in VMC. (biomedcentral.com)
Skeletal muscle2
  • Skeletal muscle, by virtue of its mass and high rate of insulin-stimulated glucose transport, represents an important tissue in the development of insulin resistance ( 1 ). (diabetesjournals.org)
  • 2,4 Studies from our group have shown that increased tissue expression of angiotensin II via stimulation of the angiotensin II type 1 receptor (AT 1 R) can cause mitochondrial morphological and functional abnormalities in skeletal muscle, and liver ( Figure 1 ) as well as cardiovascular tissue ( Figure 2 ). (ahajournals.org)
Mitochondria16
  • Transport is fully reversible, and its directionality is governed by the concentrations of its substrates (ADP and ATP inside and outside mitochondria), the chelators of the adenine nucleotides, and the mitochondrial membrane potential. (wikipedia.org)
  • In the present investigation, we used the inhibitor CAtr (carboxyatractyloside) to examine the involvement of the ANT (adenine nucleotide translocator) in the mediation of this UCP1-independent fatty-acid-induced uncoupling in brown-fat mitochondria. (portlandpress.com)
  • Additionally, palmitic acid but not palmitoleic acid decreased the expression of the mitochondrial adenine nucleotide translocator and induced release of cytochrome c from the mitochondria into the cytosol. (diabetesjournals.org)
  • We investigated the mechanism of HA14-1-induced apoptosis and found that HA14-1 induces translocation of Bax from cytosols to the mitochondria. (aacrjournals.org)
  • To eliminate the effect of cytosolic Bax, we incubated cell-free mitochondria with HA14-1 to study its effect on cytochrome c release. (aacrjournals.org)
  • HA14-1 was ineffective in causing cytochrome c release from the purified mitochondria. (aacrjournals.org)
  • However, the combination of HA14-1 and PK11195, an antagonist of peripheral benzodiazepine receptor of the mitochondria, enhanced the cytochrome c release by HA14-1. (aacrjournals.org)
  • When Bcl-2 is inhibited by HA14-1, Bax translocated to the mitochondria. (aacrjournals.org)
  • The main components of this pore are adenine nucleotide translocator and cyclophilin D in the inner membrane of the mitochondria, and voltage-dependent anion channel and peripheral benzodiazepine receptor in the outer mitochondrial membrane. (aacrjournals.org)
  • Phosphoproteome analysis of isoflurane-protected heart mitochondria: phosphorylation of adenine nucleotide translocator-1 on Tyr194 regulates mitochondrial function. (uzh.ch)
  • Purified mitochondria were treated with 1 μM Vpr52-96 subjected to cytofluorometric determination of the percentage of mitochondria having a low ΔΨm using the ΔΨm-sensitive fluorochrome JC-1. (nih.gov)
  • This conclusion is based on in vivo observations of the direct localization of HIV-1 PR in mitochondria, a key player in triggering apoptosis. (biomedcentral.com)
  • The roles of mitochondria in the generation of energy, 1 the production of reactive oxygen species (ROS), 2 the regulation of calcium homeostasis, 3 and the orchestration of apoptosis 4 are all widely recognized. (ahajournals.org)
  • The AGK gene encodes the mitochondrial acylglycerol kinase which plays a role in the assembly of adenine nucleotide translocator (ANT), an essential component of the oxidative phosphorylation in mitochondria. (orpha.net)
  • 1) Bid and tBid have a high-affinity binding domain for a mitochondria specific phospholipid, cardiolipin (CL). (cdc.gov)
  • 4,12) Cyt c is an important contributor to redox reactions in the intermembrane space of mitochondria where it functions as (1) an electron shuttle between respiratory complexes III and IV and (2) a scavenger of superoxide anion radicals. (cdc.gov)
SLC25A42
  • adenine nucleotide translocator), member 4) The peptide sequence was selected from the N terminal of SLC25A4. (novusbio.com)
  • The SLC25A4 gene encodes the heart and muscle specific isoform 1 of the mitochondrial ANT. (orpha.net)
AAC11
  • Adenine nucleotide transporter, ANT, or ATP:ADP carrier AAC1 (one of three paralogues). (tcdb.org)
Isoform2
  • Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction. (escholarship.org)
  • The mouse fetal and adult hearts express two adenine nucleotide translocator (ANT) isoform genes. (escholarship.org)
Antibody1
  • Auto-antibody against adenine nucleotide translocator in dilated cardiomyopathy and myocarditis. (nii.ac.jp)
Genes1
  • Less commonly, mutations that change single nucleotides in genes found in mtDNA, such as the MT-TL1 gene, cause progressive external ophthalmoplegia. (medlineplus.gov)
MPTP1
  • Lack of UCP2 increased the sensitivity of dopamine neurons to 1-methyl-4-phenyl-1,2,5,6 tetrahydropyridine (MPTP), whereas UCP2 overexpression decreased MPTP-induced nigral dopamine cell loss. (jneurosci.org)
VDAC2
  • This PTP complex includes PBR, VDAC, adenine nucleotide translocator, and cyclophilin D ( 9 ). (aacrjournals.org)
  • In addition, in vitro data demonstrated that HIV-1 PR mediates cleavage of mitochondrial proteins Tom22, VDAC and ANT, leading to release of AIF and Hsp60 proteins. (biomedcentral.com)
Adenosine2
  • Synthetic peptide, conjugated to KLH, corresponding to residues C G(1) D Q A L S F L K D F(11) of rat Adenosine Nucleotide Translocator 1. (thermofisher.com)
  • In the earliest study on this subject, the MPT was shown to be induced by high concentrations of mitochondrial Ca 2+ ([Ca 2+ ] m ) and to be inhibited by Mg 2+ and adenosine diphosphate (ADP) ( 1 ). (frontiersin.org)
Proteins8
  • The human mitochondrion contains at least 100 different proteins directly involved in the mitochondrial energy-generating system (MEGS) [3] (1). (thefreelibrary.com)
  • Inactivation of uncoupler proteins (Ucp) 1-3 revealed that mitochondrial Delta Psi regulated ROS production. (nih.gov)
  • In addition, it can become activated by binding BCL-2, as well as non-BCL-2 proteins such as p53 and Bif-1. (wikipedia.org)
  • To determine if uncoupling proteins (UCP2 or UCP3), or ANT activity contributed to MITO uncoupling in db/db hearts, 500μM GDP and 5μM atractyloside (ATR) were sequentially added to fibers at state 4 respiration conditions (1μg/mL oligomycin). (ahajournals.org)
  • Adenine nucleotide translocators (ANTs) are mitochondrial carrier proteins that exchange ATP and ADP between the cytoplasm and the mitochondrial matrix. (ptglab.com)
  • Their genome is organized in eight RNA segments, encoding up to 13 proteins [ 1 , 2 , 3 ]. (mdpi.com)
  • Roles for herpes simplex virus type 1 UL34 and US3 proteins in disrupting the nuclear lamina during herpes simplex virus type 1 egress. (microbiologyresearch.org)
  • Herpes simplex virus type 1 tegument proteins VP1/2 and UL37 are associated with intranuclear capsids. (microbiologyresearch.org)
Solute Carrie1
  • SLC25A6P1 (Solute Carrier Family 25 Member 6 Pseudogene 1) is a Pseudogene, and is affiliated with the lncRNA class. (genecards.org)
Mechanistic target of rapamycin1
  • The mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) is a master regulator of cell growth and metabolism. (readbyqxmd.com)
Molecular3
  • HA14-1 is a small molecular compound that was identified based on the structure of Bcl-2. (aacrjournals.org)
  • Molecular Ecology:1-35. (uzh.ch)
  • Methods in Molecular Biology, 780(Part 1):57-66. (uzh.ch)
Apoptosis11
  • Further, we demonstrate that both in vitro and in vivo, PIs block apoptosis through the preservation of mitochondrial integrity and that in vitro PIs act to prevent pore function of the adenine nucleotide translocator (ANT) subunit of the mitochondrial permeability transition pore complex. (jci.org)
  • Cells deficient in Bax were much more resistant to HA14-1-induced apoptosis, suggesting that Bax is required for this process. (aacrjournals.org)
  • The combination of PK11195 and HA14-1 could therefore serve as a potentially useful approach to enhance apoptosis in cancer. (aacrjournals.org)
  • The Bcl-2 family apoptotic regulators are the key players in the regulation of apoptosis ( 1 , 2 ). (aacrjournals.org)
  • Preliminary studies demonstrated that HA14-1 strongly induced apoptosis in NIH3T3, HL60, and lung cancer H1299 cell lines with an IC 50 in the range of 10-20 μ m ( 5 ). (aacrjournals.org)
  • We investigated the mechanism of HA14-1-induced apoptosis. (aacrjournals.org)
  • HIV-1 protease (PR) has been suggested as a possible factor, but a direct link between HIV-1 PR enzymatic activity and apoptosis has not been established. (biomedcentral.com)
  • Extracellular ADP prevents neuronal apoptosis via activation of cell antioxidant enzymes and protection of mitochondrial ANT-1. (genscript.com)
  • The hallmark of HIV-1 pathogenesis is the progressive CD4(+) T cell depletion and high propensity of CD4(+) T cells to apoptosis. (pasteur.fr)
  • Experiments combining pull-down, cell penetration and apoptosis analyses in distinct human cells indicate that the PP2A(1) binding sequence from Vpr(77-92) is a new cell penetrating apoptotic sequence. (pasteur.fr)
  • We also found that the I84P mutation or the IIQ/VTR(83-85) and T89A substitutions in the Vpr(77-92) sequence prevent PP2A(1) binding, cell penetration and apoptosis. (pasteur.fr)
Nicotinamide11
  • Electrons (e − ) from carbon oxidations are transferred via NADH (nicotinamide adenine dinucleotide) into OXPHOS complex I, which is embedded in the lipid bilayer of the mitochondrial inner membrane (IMM), then transported to coenzyme Q (Q). Some electrons from organic‐acid oxidations are transferred, via other flavin‐containing enzyme complexes directly to CoQ. (els.net)
  • Prononciation de nicotinamide adenine dinucleotide phosphate à 1 prononciation audio, 2 synonymes, 1 sens, 7 traductions, et de plus pour nicotinamide adenine dinucleotide phosphate. (losangelesorienteering.org)
  • Comment dire nicotinamide adenine dinucleotide phosphate Anglais? (losangelesorienteering.org)
  • Pronunciation of nicotinamide adenine dinucleotide. (losangelesorienteering.org)
  • Health Details: Pronunciation of nicotinamide adenine dinucleotide with 2 audio pronunciations, 7 synonyms, 10 translations and more for nicotinamide adenine dinucleotide. (losangelesorienteering.org)
  • Hogyan kell mondani nicotinamide adenine dinucleotide Angol? (losangelesorienteering.org)
  • How do you pronounce nicotinamide adenine dinucleotide in English? (losangelesorienteering.org)
  • Pronunciation of Nicotinamide adenine with 1 audio pronunciation and more for Nicotinamide adenine. (losangelesorienteering.org)
  • C57BL/6J mice (Mus musculus) have a mutant allele of nicotinamide nucleotide transhydrogenase (Nnt) that can act as a modifier. (escholarship.org)
  • Loss of NNT decreases the concentration of reduced nicotinamide adenine dinucleotide phosphate within the mitochondrial matrix. (escholarship.org)
  • Nicotinamide adenine dinucleotide phosphate is a cofactor for glutathione reductase, which regenerates reduced glutathione, an important antioxidant. (escholarship.org)
Transporter1
  • Mitochondrial CK in the mitochondrial outer compartment, for example, is tightly coupled to ATP export via adenine nucleotide transporter or carrier (ANT) and thus ATP-synthesis and respiratory chain activity, releasing PCr into the cytosol. (springer.com)
Pore1
  • Bongkrekic acid is a mitochondrial permeability transition pore blocker that acts as an inhibitory ligand of the mitochondrial adenine nucleotide translocator. (scbt.com)
ANT21
  • Using a knockin X-linked Ant2 allele in which exons 3 and 4 are flanked by loxP sites combined in males with a protamine 1 promoter driven Cre recombinase we created females heterozygous for a null Ant2 allele. (escholarship.org)
Cardiac1
  • 1-3 Both hyperthyroidism and hypothyroidism produce changes in cardiac contractility, myocardial oxygen consumption, cardiac output, blood pressure, and systemic vascular resistance (SVR). (ahajournals.org)
Oxidative phosphorylation2
  • Because oxidative phosphorylation was not disturbed in fibroblasts and lymphocytes, we conclude that this patient suffers from a muscle-specific deficiency of his mitochondrial adenine nucleotide translocator, a defect unknown so far. (nature.com)
  • The mitochondrial oxidative phosphorylation (OXPHOS) system consists of four electron transport chain (ETC) complexes (CI-CIV) and the F o F 1 -ATP synthase (CV), which sustain ATP generation via chemiosmotic coupling. (chemweb.com)
Purine base1
  • Adenine definition is - a purine base C5H5N5 that codes hereditary information in the genetic code in DNA and RNA. (losangelesorienteering.org)
Pyruvate3
  • Complete oxidation of 1 mole of pyruvate delivers 15 moles of ATP. (thefreelibrary.com)
  • 0.001) in isolated db/db MITO exposed to the complex 1 substrate pyruvate. (ahajournals.org)
  • It plays a very important role in the assembly and maintenance of functionally active respiratory complexes (I, III and IV and F0/F1-ATPase) in the mitochondrial membrane and in normal operation of other mitochondrial multicomponent machines such as adenine nucleotide translocator, as well as tricarboxylate, pyruvate and phosphate carriers. (cdc.gov)
Expression5
  • Ji-Young Jang and Choong-Eun Lee, "Expression of Adenine Nucleotide Translocator Correlates with the IL-4-induced lymphocyte survival: Role of PI3K and MAPK," TheScientificWorldJOURNAL , vol. 1, pp. 100-100, 2001. (hindawi.com)
  • Distinguishing features of Tfh cells include CXC chemokine receptor 5 (CXCR5) expression, inducible co-stimulator (ICOS), programmed death 1(PD-1), and the secretion of interleukin (IL)-21(IL-21). (biomedcentral.com)
  • Here, we show that expression of active HIV-1 PR induces death in HeLa and HEK-293 cells via the mitochondrial apoptotic pathway. (biomedcentral.com)
  • Laminin .ALPHA.1, .ALPHA.2, .ALPHA.4 and .BETA.1 Chain mRNA Expression in Mouse Embryonic, Neonatal, and Adult Hearts. (nii.ac.jp)
  • Expression of Type XVII Collagen .ALPHA.1 Chain mRNA in the Mouse Heart. (nii.ac.jp)
Inner mitochon1
  • The mitochondrial permeability transition (MPT) refers to an alteration in the permeability of the inner mitochondrial membrane (IMM), which was characterized for the first time in 1979 ( 1 ). (frontiersin.org)
Peptides2
  • Mapping of antigenic determinants of the adenine- nucleotide translocator and coxsackie B3 virus with synthetic peptides: use for the diagnosis of viral heart disease. (springer.com)
  • We show that both peptides inhibit the formation of PAI 1/uPA and PAI-1/tPA complexes via two different mechanisms. (ac.be)
Phosphorylation2
  • Although the exact manner by which mitochondrial ROS causes insulin resistance has not been delineated, it has been suggested that activation of the NF-κB/IκB/IKKβ pathway results in serine phosphorylation of the insulin receptor substrate 1 (IRS1), attenuating insulin signaling at a proximal step ( 12 , 13 ). (diabetesjournals.org)
  • In cancer cells, the interaction with CAFs supported glycogenolysis under normoxic conditions and induced phosphorylation and activation of phosphoglucomutase 1, an enzyme involved in glycogen metabolism. (readbyqxmd.com)
FSHD4
  • the shortened Eco RI fragment in FSHD is 1-10 units. (medscape.com)
  • Those without FSHD have approximately 11-100 D4Z4 units, whereas patients with FSHD have 1-10 D4Z4 units. (medscape.com)
  • At least 1 copy of D4Z4 is required to develop FSHD. (medscape.com)
  • Misexpression of FRG1 (FSHD region gene 1) may lead to the development of FSHD. (medscape.com)
Abstract1
Primary antibodies1
  • Primary Antibodies are guaranteed for 1 year from date of receipt. (novusbio.com)
Inhibit1
  • A pan-caspase inhibitor failed to inhibit the apoptotic effect of HA14-1, indicating that this is through a caspase-independent pathway. (aacrjournals.org)
Redox1
  • In biochemistry, flavin adenine dinucleotide is a redox cofactor, more specifically a prosthetic group, involved in several important reactions in metabolism. (losangelesorienteering.org)
Metabolism3
  • Fructose-1,6-bisphosphatase (FBPase) catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and is a key enzyme of gluconeogenesis and glyconeogenesis and, more generally, of the control of energy metabolism and glucose homeostasis. (iucr.org)
  • The excitatory potency of the acidic amino acids glutamate and aspartate in various regions of the central nervous system (CNS) has been recognized since the 1960 s. 1,2 Nevertheless, the earlier findings that these amino acids are ( 1 ) constituents of intermediary metabolism and are ( 2 ) located in the brain ubiquitously in high concentrations rendered them unlikely candidates as neurotransmitters. (springer.com)
  • Tetraphenylphosphonium was shown to be a useful chemical indicator of the mitochondrial membrane potential (ΔΨm) in 1969 ( 1 ) and has been used for in vitro studies of myocardial metabolism ( 2-7 ) and tumor imaging in which differences between normal and malignant cell ΔΨm are exploited to facilitate tumor identification ( 8 ). (onlinejacc.org)
Carrier1
  • 2-oxodicarboxylate carrier 1 (ODC1) transports C5-C7 oxodicarboxylic acid (2-oxoadipate, 2-oxoglularate, adipate, glutarate, 2-oxopimelate, oxaloacetate, citrate and malate) (functions by a strict antiport mechanism (Palmieri et al. (tcdb.org)
20011
  • Spring 2001;106(1):71-93. (nih.gov)
Cellular2
  • Following the discovery of adenine nucleotides, and their role in cellular energetics as a key link between spatially separated energy transducing processes, the energy transfer concept through the 'adenylate wire' was proposed ( Lipmann,1941 ). (biologists.org)
  • Herpes simplex virus type 1 (HSV-1) capsids assemble in the nucleus but acquire their teguments from various cellular compartments. (microbiologyresearch.org)
NADH1
  • A) Respirometry performed after addition of NADH and Vpr52-96 (1 μM). (nih.gov)
Table of Contents - August 04, 2000, 289 (5480) | Science
Table of Contents - August 04, 2000, 289 (5480) | Science (science.sciencemag.org)
Adenine nucleotide translocator - definition of Adenine nucleotide translocator by The Free Dictionary
Adenine nucleotide translocator - definition of Adenine nucleotide translocator by The Free Dictionary (thefreedictionary.com)
SLC25A4 gene: MedlinePlus Genetics
SLC25A4 gene: MedlinePlus Genetics (medlineplus.gov)
Phosphotransfer networks and cellular energetics | Journal of Experimental Biology
Phosphotransfer networks and cellular energetics | Journal of Experimental Biology (jeb.biologists.org)
Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab221956) | Abcam
Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab221956) | Abcam (abcam.com)
Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab192410) | Abcam
Anti-Adenine Nucleotide Translocator 2/ANT 2 antibody (ab192410) | Abcam (abcam.com)
Adenine Nucleotide Translocase 1 Antibody (NBP1-59594): Novus Biologicals
Adenine Nucleotide Translocase 1 Antibody (NBP1-59594): Novus Biologicals (novusbio.com)
Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma | JEM
Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma | JEM (jem.rupress.org)
Oxidative Phosphorylation System: Nuclear Genes and Genetic Disease
Oxidative Phosphorylation System: Nuclear Genes and Genetic Disease (els.net)
Porins in prokaryotes and eukaryotes: common themes and variations | Biochemical Journal
Porins in prokaryotes and eukaryotes: common themes and variations | Biochemical Journal (biochemj.org)
JCI - Volume 115, Issue 7
JCI - Volume 115, Issue 7 (jci.org)
SLC25A4 (Human) Recombinant Protein (P01) - (H00000291-P01) - Products - Abnova
SLC25A4 (Human) Recombinant Protein (P01) - (H00000291-P01) - Products - Abnova (abnova.com)
Facioscapulohumeral Dystrophy: Background, Pathophysiology, Epidemiology
Facioscapulohumeral Dystrophy: Background, Pathophysiology, Epidemiology (emedicine.medscape.com)
Browse our SLC25A6 ELISA Kits
Browse our SLC25A6 ELISA Kits (antibodies-online.com)
Progressive external ophthalmoplegia: MedlinePlus Genetics
Progressive external ophthalmoplegia: MedlinePlus Genetics (medlineplus.gov)
New analytical screening tools for the detection of cardiovascular disease | EurekAlert! Science News
New analytical screening tools for the detection of cardiovascular disease | EurekAlert! Science News (eurekalert.org)
Slc25a13 (untagged) - Mouse solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 ...
Slc25a13 (untagged) - Mouse solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 ... (acris-antibodies.com)
Mechanisms of Heart Failure | Springer for Research & Development
Mechanisms of Heart Failure | Springer for Research & Development (rd.springer.com)
Browse by Communities & Collections - Zurich Open Repository and Archive
Browse by Communities & Collections - Zurich Open Repository and Archive (zora.uzh.ch)
The creatine kinase system and pleiotropic effects of creatine | SpringerLink
The creatine kinase system and pleiotropic effects of creatine | SpringerLink (link.springer.com)
Throat infection, neck and chest pain and cardiac response: A persistent infection-related clinical syndrome | SpringerLink
Throat infection, neck and chest pain and cardiac response: A persistent infection-related clinical syndrome | SpringerLink (link.springer.com)
Development of a porcine skeletal muscle cDNA microarray: analysis of differential transcript expression in phenotypically...
Development of a porcine skeletal muscle cDNA microarray: analysis of differential transcript expression in phenotypically... (bmcgenomics.biomedcentral.com)
Increased frequency of follicular helper T cells in mice viral myocarditis is relevant with anti-ANT antoantibody | Virology...
Increased frequency of follicular helper T cells in mice viral myocarditis is relevant with anti-ANT antoantibody | Virology... (virologyj.biomedcentral.com)
Bongkrekic acid | CAS 11076-19-0 | SCBT - Santa Cruz Biotechnology
Bongkrekic acid | CAS 11076-19-0 | SCBT - Santa Cruz Biotechnology (scbt.com)
Community Academic Profiles - Faculty & Researchers - Stanford Medicine
Community Academic Profiles - Faculty & Researchers - Stanford Medicine (med.stanford.edu)
TGF-β1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors |...
TGF-β1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors |... (bmcneurosci.biomedcentral.com)
Plus it
Plus it (cancerres.aacrjournals.org)
Plus it
Plus it (jneurosci.org)
Sengers syndrome | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program
Sengers syndrome | Genetic and Rare Diseases Information Center (GARD) - an NCATS Program (rarediseases.info.nih.gov)
Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction.
Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction. (escholarship.org)
Combining Experimental and Predicted Datasets for Determination of the Subcellular Location of Proteins in Arabidopsis | Plant...
Combining Experimental and Predicted Datasets for Determination of the Subcellular Location of Proteins in Arabidopsis | Plant... (plantphysiol.org)