Adaptation, Physiological
Adaptation, Ocular
Adaptation, Biological
Models, Biological
Dark Adaptation
Biological Evolution
Biological Products
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Biological Assay
A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc.
Biological Therapy
Adaptation, Psychological
Figural Aftereffect
Amino Acid Sequence
Gene Expression Profiling
Evolution, Molecular
Photic Stimulation
Algorithms
Computer Simulation
Biological Warfare
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Mutation
Computational Biology
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
Signal Transduction
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Selection, Genetic
Biological Processes
Base Sequence
Species Specificity
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
Dental Marginal Adaptation
Phenotype
Oligonucleotide Array Sequence Analysis
Sequence Analysis, DNA
Models, Genetic
Environment
Models, Molecular
Structure-Activity Relationship
Pest Control, Biological
Software
Stress, Physiological
Ecosystem
Reproducibility of Results
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Proteins
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Temperature
Gene Expression Regulation
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Protein Binding
Cluster Analysis
A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.
Molecular Structure
Biological Clocks
Escherichia coli
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Systems Biology
Metabolic Networks and Pathways
Gene Regulatory Networks
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Cells, Cultured
Altitude
Contrast Sensitivity
Sequence Alignment
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
Visual Perception
Analysis of Variance
Models, Theoretical
Models, Neurological
Psychomotor Performance
Biomechanical Phenomena
Muscle, Skeletal
Photoreceptor Cells
Specialized cells that detect and transduce light. They are classified into two types based on their light reception structure, the ciliary photoreceptors and the rhabdomeric photoreceptors with MICROVILLI. Ciliary photoreceptor cells use OPSINS that activate a PHOSPHODIESTERASE phosphodiesterase cascade. Rhabdomeric photoreceptor cells use opsins that activate a PHOSPHOLIPASE C cascade.
Tumor Markers, Biological
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Biological Transport
Protein Structure, Tertiary
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Climate Change
Any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.
Movement
The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.
Psychophysics
Genetic Fitness
Gene Expression
Perceptual Distortion
Binding Sites
Neurons
Vision, Ocular
Fermentation
Transcription Factors
Oxygen
Gene Expression Regulation, Bacterial
Biology
Mass Spectrometry
Chromatography, High Pressure Liquid
Transcription, Genetic
Learning
Transcriptome
Neoplasms
Protein Conformation
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
DNA
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Dose-Response Relationship, Drug
Peptides
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Reverse Transcriptase Polymerase Chain Reaction
Hydrogen-Ion Concentration
Models, Statistical
Cattle
Sequence Homology, Amino Acid
Action Potentials
Saccharomyces cerevisiae
Pattern Recognition, Visual
Energy Metabolism
Magnetic Resonance Spectroscopy
Rats, Sprague-Dawley
Saccades
Genome
Oxidation-Reduction
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Relative Biological Effectiveness
Cloning, Molecular
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Plants
Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.
Genotype
User-Computer Interface
Rotation
Ecology
The branch of science concerned with the interrelationship of organisms and their ENVIRONMENT, especially as manifested by natural cycles and rhythms, community development and structure, interactions between different kinds of organisms, geographic distributions, and population alterations. (Webster's, 3d ed)
Geography
Water
Carbon
Cell Membrane
Cell Division
Genetics, Population
Retina
The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.
Phosphorylation
Virulence
Aging
Stress, Mechanical
Face
Fungi
A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.
Lenses
Feedback
Databases, Factual
Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.
Membrane Proteins
Blotting, Western
Short Bowel Syndrome
Circadian Rhythm
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Climate
Internet
Chemotaxis
Immunohistochemistry
Biological Control Agents
Calcium
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Amino Acids
Cell Survival
Disease Models, Animal
Lighting
DNA Primers
Fishes
Homeostasis
Molecular Sequence Annotation
Color Perception
Mental processing of chromatic signals (COLOR VISION) from the eye by the VISUAL CORTEX where they are converted into symbolic representations. Color perception involves numerous neurons, and is influenced not only by the distribution of wavelengths from the viewed object, but also by its background color and brightness contrast at its boundary.
Retinal Rod Photoreceptor Cells
Photosensitive afferent neurons located in the peripheral retina, with their density increases radially away from the FOVEA CENTRALIS. Being much more sensitive to light than the RETINAL CONE CELLS, the rod cells are responsible for twilight vision (at scotopic intensities) as well as peripheral vision, but provide no color discrimination.
Physical Conditioning, Animal
Bayes Theorem
A theorem in probability theory named for Thomas Bayes (1702-1761). In epidemiology, it is used to obtain the probability of disease in a group of people with some characteristic on the basis of the overall rate of that disease and of the likelihood of that characteristic in healthy and diseased individuals. The most familiar application is in clinical decision analysis where it is used for estimating the probability of a particular diagnosis given the appearance of some symptoms or test result.
Apoptosis
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Information Storage and Retrieval
Host-Pathogen Interactions
Biological Science Disciplines
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.
Pregnancy
Feedback, Sensory
Mechanotransduction, Cellular
Multigene Family
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Ligands
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
Models, Chemical
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Rabbits
Nitrogen
Computer Graphics
Feedback, Physiological
Mammals
Channeling of carbamoyl phosphate to the pyrimidine and arginine biosynthetic pathways in the deep sea hyperthermophilic archaeon Pyrococcus abyssi. (1/2155)
The kinetics of the coupled reactions between carbamoyl-phosphate synthetase (CPSase) and both aspartate transcarbamoylase (ATCase) and ornithine transcarbamoylase (OTCase) from the deep sea hyperthermophilic archaeon Pyrococcus abyssi demonstrate the existence of carbamoyl phosphate channeling in both the pyrimidine and arginine biosynthetic pathways. Isotopic dilution experiments and coupled reaction kinetics analyzed within the context of the formalism proposed by Ovadi et al. (Ovadi, J., Tompa, P., Vertessy, B., Orosz, F., Keleti, T., and Welch, G. R. (1989) Biochem. J. 257, 187-190) are consistent with a partial channeling of the intermediate at 37 degrees C, but channeling efficiency increases dramatically at elevated temperatures. There is no preferential partitioning of carbamoyl phosphate between the arginine and pyrimidine biosynthetic pathways. Gel filtration chromatography at high and low temperature and in the presence and absence of substrates did not reveal stable complexes between P. abyssi CPSase and either ATCase or OTCase. Thus, channeling must occur during the dynamic association of coupled enzymes pairs. The interaction of CPSase-ATCase was further demonstrated by the unexpectedly weak inhibition of the coupled reaction by the bisubstrate analog, N-(phosphonacetyl)-L-aspartate (PALA). The anomalous effect of PALA suggests that, in the coupled reaction, the effective concentration of carbamoyl phosphate in the vicinity of the ATCase active site is 96-fold higher than the concentration in the bulk phase. Channeling probably plays an essential role in protecting this very unstable intermediate of metabolic pathways performing at extreme temperatures. (+info)The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex. (2/2155)
When mammalian cells are subjected to calcium depletion stress or protein glycosylation block, the transcription of a family of glucose-regulated protein (GRP) genes encoding endoplasmic reticulum (ER) chaperones is induced to high levels. The consensus mammalian ER stress response element (ERSE) conserved among grp promoters consists of a tripartite structure CCAAT(N9)CCACG, with N being a strikingly GC-rich region of 9 bp. The ERSE, in duplicate copies, can confer full stress inducibility to a heterologous promoter in a sequence-specific but orientation-independent manner. In addition to CBF/NF-Y and YY1 binding to the CCAAT and CCACG motifs, respectively, we further discovered that an ER stress-inducible complex (ERSF) from HeLa nuclear extract binds specifically to the ERSE. Strikingly, the interaction of the ERSF with the ERSE requires a conserved GGC motif within the 9 bp region. Since mutation of the GGC triplet sequence also results in loss of stress inducibility, specific sequence within the 9 bp region is an integral part of the tripartite structure. Finally, correlation of factor binding with stress inducibility reveals that ERSF binding to the ERSE alone is not sufficient; full stress inducibility requires integrity of the CCAAT, GGC and CCACG sequence motifs, as well as precise spacing among these sites. (+info)Shared usage of the chemokine receptor CXCR4 by primary and laboratory-adapted strains of feline immunodeficiency virus. (3/2155)
Strains of the feline immunodeficiency virus (FIV) presently under investigation exhibit distinct patterns of in vitro tropism. In particular, the adaptation of FIV for propagation in Crandell feline kidney (CrFK) cells results in the selection of strains capable of forming syncytia with cell lines of diverse species origin. The infection of CrFK cells by CrFK-adapted strains appears to require the chemokine receptor CXCR4 and is inhibited by its natural ligand, stromal cell-derived factor 1alpha (SDF-1alpha). Here we found that inhibitors of CXCR4-mediated infection by human immunodeficiency virus type I (HIV-1), such as the bicyclam AMD3100 and short peptides derived from the amino-terminal region of SDF-1alpha, also blocked infection of CrFK by FIV. Nevertheless, we observed differences in the ranking order of the peptides as inhibitors of FIV and HIV-1 and showed that such differences are related to the species origin of CXCR4 and not that of the viral envelope. These results suggest that, although the envelope glycoproteins of FIV and HIV-1 are substantially divergent, FIV and HIV-1 interact with CXCR4 in a highly similar manner. We have also addressed the role of CXCR4 in the life cycle of primary isolates of FIV. Various CXCR4 ligands inhibited infection of feline peripheral blood mononuclear cells (PBMC) by primary FIV isolates in a concentration-dependent manner. These ligands also blocked the viral transduction of feline PBMC by pseudotyped viral particles when infection was mediated by the envelope glycoprotein of a primary FIV isolate but not by the G protein of vesicular stomatitis virus, indicating that they act at an envelope-mediated step and presumably at viral entry. These findings strongly suggest that primary and CrFK-adapted strains of FIV, despite disparate in vitro tropisms, share usage of CXCR4. (+info)Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1. (4/2155)
The relative replicative fitness of human immunodeficiency virus type 1 (HIV-1) mutants selected by different protease inhibitors (PIs) in vivo was determined. Each mutant was compared to wild type (WT), NL4-3, in the absence of drugs by several methods, including clonal genotyping of cultures infected with two competing viral variants, kinetics of viral antigen production, and viral infectivity/virion particle ratios. A nelfinavir-selected protease D30N substitution substantially decreased replicative capacity relative to WT, while a saquinavir-selected L90M substitution moderately decreased fitness. The D30N mutant virus was also outcompeted by the L90M mutant in the absence of drugs. A major natural polymorphism of the HIV-1 protease, L63P, compensated well for the impairment of fitness caused by L90M but only slightly improved the fitness of D30N. Multiply substituted indinavir-selected mutants M46I/L63P/V82T/I84V and L10R/M46I/L63P/V82T/I84V were just as fit as WT. These results indicate that the mutations which are usually initially selected by nelfinavir and saquinavir, D30N and L90M, respectively, impair fitness. However, additional mutations may improve the replicative capacity of these and other drug-resistant mutants. Hypotheses based on the greater fitness impairment of the nelfinavir-selected D30N mutant are suggested to explain observations that prolonged responses to delayed salvage regimens, including alternate PIs, may be relatively common after nelfinavir failure. (+info)Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells. (5/2155)
The natural life cycle of alphaviruses, a group of plus-strand RNA viruses, involves transmission to vertebrate hosts via mosquitoes. Chronic infections are established in mosquitoes (and usually in mosquito cell cultures), but infection of susceptible vertebrate cells typically results in rapid shutoff of host mRNA translation and cell death. Using engineered Sindbis virus RNA replicons expressing puromycin acetyltransferase as a dominant selectable marker, we identified mutations allowing persistent, noncytopathic replication in BHK-21 cells. Two of these adaptive mutations involved single-amino-acid substitutions in the C-terminal portion of nsP2, the viral helicase-protease. At one of these loci, nsP2 position 726, numerous substitution mutations were created and characterized in the context of RNA replicons and infectious virus. Our results suggest a direct correlation between the level of viral RNA replication and cytopathogenicity. This work also provides a series of alphavirus replicons for noncytopathic gene expression studies (E. V. Agapov, I. Frolov, B. D. Lindenbach, B. M. Pragai, S. Schlesinger, and C. M. Rice, Proc. Natl. Acad. Sci. USA 95:12989-12994, 1998) and a general strategy for selecting RNA viral mutants adapted to different cellular environments. (+info)Genetic and fitness changes accompanying adaptation of an arbovirus to vertebrate and invertebrate cells. (6/2155)
The alternating host cycle and persistent vector infection may constrain the evolution of arboviruses. To test this hypothesis, eastern equine encephalitis virus was passaged in BHK or mosquito cells, as well as in alternating (both) host cell passages. High and low multiplicities were used to examine the effect of defective interfering particles. Clonal BHK and persistent mosquito cell infections were also evaluated. Fitness was measured with one-step growth curves and competition assays, and mutations were evaluated by nucleotide sequencing and RNA fingerprinting. All passages and assays were done at 32 degrees C to eliminate temperature as a selection factor. Viruses passaged in either cell type alone exhibited fitness declines in the bypassed cells, while high-multiplicity and clonal passages caused fitness declines in both types of cells. Bypassed cell fitness losses were mosquito and vertebrate specific and were not restricted to individual cell lines. Fitness increases occurred in the cell line used for single-host-adaptation passages and in both cells for alternately passaged viruses. Surprisingly, single-host-cell passage increased fitness in that cell type no more than alternating passages. However, single-host-cell adaptation resulted in more mutations than alternating cell passages. Mosquito cell adaptation invariably resulted in replacement of the stop codon in nsP3 with arginine or cysteine. In one case, BHK cell adaptation resulted in a 238-nucleotide deletion in the 3' untranslated region. Many nonsynonymous substitutions were shared among more than one BHK or mosquito cell passage series, suggesting positive Darwinian selection. Our results suggest that alternating host transmission cycles constrain the evolutionary rates of arboviruses but not their fitness for either host alone. (+info)The steady-state internal redox state (NADH/NAD) reflects the external redox state and is correlated with catabolic adaptation in Escherichia coli. (7/2155)
Escherichia coli MC4100 was grown in anaerobic glucose-limited chemostat cultures, either in the presence of an electron acceptor (fumarate, nitrate, or oxygen) or fully fermentatively. The steady-state NADH/NAD ratio depended on the nature of the electron acceptor. Anaerobically, the ratio was highest, and it decreased progressively with increasing midpoint potential of the electron acceptor. Similarly, decreasing the dissolved oxygen tension resulted in an increased NADH/NAD ratio. As pyruvate catabolism is a major switch point between fermentative and respiratory behavior, the fluxes through the different pyruvate-consuming enzymes were calculated. Although pyruvate formate lyase (PFL) is inactivated by oxygen, it was inferred that the in vivo activity of the enzyme occurred at low dissolved oxygen tensions (DOT +info)cis-Acting elements responsible for low-temperature-inducible expression of the gene coding for the thermolabile isocitrate dehydrogenase isozyme of a psychrophilic bacterium, Vibrio sp. strain ABE-1. (8/2155)
Transcriptional control of the low-temperature-inducible icdII gene, encoding the thermolabile isocitrate dehydrogenase of a psychrophilic bacterium, Vibrio sp. strain ABE-1, was found to be mediated in part by a transcriptional silencer locating at nucleotide positions -560 to -526 upstream from the transcription start site of icdII. Deletion of the silencer resulted in a 20-fold-increased level of expression of the gene at low temperature (15 degrees C) but not at high temperature (37 degrees C). In addition, a CCAAT sequence located 2 bases upstream of the -35 region was found to be essential for the low-temperature-inducible expression of the gene. By deletion of this sequence, low-temperature-dependent expression of the gene was completely abolished. The ability of the icdII promoter to control the expression of other genes was confirmed by using a fusion gene containing the icdII promoter region and the promoterless icdI open reading frame, which encodes the non-cold-inducible isocitrate dehydrogenase isozyme of Vibrio sp. strain ABE-1. Escherichia coli transformants harboring icdII acquired an ability to grow rapidly at low temperature. (+info)On the Accessibility of Adaptive Phenotypes of a Bacterial Metabolic Network
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Genetic architecture
Deng, Lian; Xu, Shuhua (15 June 2017). "Adaptation of human skin color in various populations". Hereditas. 155 (1): 1. doi: ... Therefore, genetic architecture can help us to answer biological questions about speciation, the evolution of sex and ... Stadler, Peter F.; Stadler, Bärbel M. R. (2015-04-14). "Genotype-Phenotype Maps". Biological Theory. 1 (3): 268-279. CiteSeerX ... Lewontin, R. C. (1978-09-01). "Adaptation". Scientific American. 239 (3): 212-218, 220, 222 passim. Bibcode:1978SciAm.239c.212L ...
Clark Spencer Larsen
3, Prehistoric human biological adaptation". Anthropological papers of the AMNH. 57 (3). (Articles with short description, ... Catherines Island: 3. Prehistoric Human Biological Adaptation. Anthropological Papers of the American Museum of Natural History ... Clark Spencer Larsen and George R. Milner (editors) (1994) In the Wake of Contact: Biological Responses to Conquest. Wiley-Liss ... Clark Spencer Larsen (born 1952) is an American biological anthropologist, author, and educator. His work focuses on ...
Epidermis (zoology)
Biological structure and function. Vol. 3. CUP Archive. pp. 15-17. ISBN 0-521-20048-2. Retrieved 21 Mar 2010. v t e (Articles ... ISBN 0-03-025982-7. Spearman, R.I.C (1973). "Function Adaptation in the Invertebrate Integument". The integument: a textbook of ...
Cynthia Beall
American Institute of Biological Sciences. Retrieved 20 June 2013. Beall CM, Laskowski D, Erzurum SC (2012). "Nitric oxide in ... Cynthia Beall is the leading scientist in the study of high-altitude adaptation in humans, particularly in places where there ... Her groundbreaking works among the Andean, Tibetan and East African highlanders are the basis of our knowledge on adaptation to ... Retrieved 20 June 2013.[permanent dead link] Beall CM (2007). "Two routes to functional adaptation: Tibetan and Andean high- ...
Psychrophile
Series B Biological Sciences. 326 (1237, Life at Low Temperatures): 595-611. Bibcode:1990RSPTB.326..595R. doi:10.1098/rstb. ... Russell NJ, Harrisson P, Johnston IA, Jaenicke R, Zuber M, Franks F, Wynn-Williams D (1990). "Cold Adaptation of Microorganisms ... Chattopadhyay, M. K.; Jagannadham, M. V. (2003). "A branched chain fatty acid promotes cold adaptation in bacteria". Journal of ... Chattopadhyay, M. K. (2006). "Mechanism of bacterial adaptation to low temperature". Journal of Biosciences. 31 (1): 157-165. ...
Extended female sexuality
Spuhler suggests that extended female sexuality has evolved as a by-product of an adaptation in females that increases the ... Gangestad, S. W.; Thornhill, R. (2008). "Human oestrus". Proceedings of the Royal Society of London B: Biological Sciences. 275 ... However, no empirical evidence has established the link between hormones and endurance walking as an adaptation and extended ... Muller, J. K.; Eggert, A. K. (1989). "Paternity assurance by helpful males: Adaptations to sperm competition in burying beetles ...
Signalling theory
Irons, W. (1996). J. P. Hurd (ed.). Morality as an Evolved Adaptation. Investigating the Biological Foundations of Morality. ... Honest biological signals do not need to be perfectly informative, reducing uncertainty to zero; all they need to be useful is ... Biological signals, like warning calls or resplendent tail feathers, are honest if they reliably convey useful information to ... Grafen, A. (1990). "Biological signals as handicaps". Journal of Theoretical Biology. 144 (4): 517-546. Bibcode:1990JThBi.144.. ...
Arctic vegetation
"Tundra - Plants - Adaptations". ThinkQuest.org. Archived from the original on May 1, 2007. McKnight, Tom L; Hess, Darrel (2000 ... Billings, WD; Mooney, HA (1968). "The ecology of Arctic and Alpine plants". Biological Reviews. 43 (4): 481-529. doi:10.1111/j. ... Arctic plants have a number of adaptations to the compressed growing season and low temperatures: They initiate growth rapidly ... Bliss, L.C. (1960). "Adaptations of arctic and alpine plants to environmental conditions". Symposium Life Under Extreme ...
Coscinasterias tenuispina
Crozier, W. J. (1920). "Notes on some problems of adaptation, 2. On the temporal relations of asexual propagation and gametic ... Biological Bulletin. 39 (2): 116-29. doi:10.2307/1536620. JSTOR 1536620. Alves, L. S. S.; A. Pereira & C. Ventura (2001). " ...
Animal echolocation
Hahn WL (1908). "Some habits and sensory adaptations of cave-inhabiting bats". Biological Bulletin. 15 (3): 135-198, especially ... Jones G, Holderied MW (April 2007). "Bat echolocation calls: adaptation and convergent evolution". Proceedings. Biological ... Adaptations in the protein Tmc1 are related to the evolution of high-frequency hearing and molecular evolution of Tmc1 and Pjvk ... Furthermore, these moth adaptations provide selective pressure for bats to improve their insect-hunting systems and this cycle ...
Action potential
1969). Biological Engineering. Inter-University Electronics Series. Vol. 9. New York: McGraw-Hill. ISBN 978-0-07-055734-5. LCCN ... Schmidt-Nielsen K (1997). Animal Physiology: Adaptation and Environment (5th ed.). Cambridge: Cambridge University Press. ISBN ... Series B, Biological Sciences. 222 (1227): 147-53. Bibcode:1984RSPSB.222..147K. doi:10.1098/rspb.1984.0055. PMID 6148754. S2CID ... Kepler TB, Abbott LF, Marder E (1992). "Reduction of conductance-based neuron models". Biological Cybernetics. 66 (5): 381-7. ...
1985 in paleontology
Series B, Biological Sciences. 309 (1139): 395-460. doi:10.1098/rstb.1985.0092. Jurcsak, T. and E. Kessler. 1985. La paleofaune ... Evolution et Adaptation 11: pp. 137-147. Federico L. Agnolin and David Varricchio (2012). "Systematic reinterpretation of Piksi ... Proceedings of the Biological Society of Washington. 98 (4): 851-855. Archived from the original (PDF) on 2015-06-16. Retrieved ... Proceedings of the Biological Society of Washington. 98 (3): 544-553. Archived from the original (PDF) on 2014-09-03. Retrieved ...
Asexual reproduction in starfish
doi:10.1016/0022-0981(86)90240-6. Crozier, W. J. (1920). "Notes on some problems of adaptation, 2. On the temporal relations of ... Fisher, W. K. (1925). "Asexual Reproduction in the Starfish, Sclerasterias" (PDF). Biological Bulletin. 48 (3): 171-175. doi: ... Biological Bulletin. 39 (2): 116-29. doi:10.2307/1536620. JSTOR 1536620. Alves, L. S. S.; A. Pereira & C. Ventura (2001). " ...
Evolutionary psychology of language
Chater, N.; Florencia, R.; Christiansen, M. H. (2009). "Restrictions on biological adaptation in language evolution". PNAS. 106 ... "Language has evolved as an adaptation" as being misleading. He argues instead that from a biological viewpoint the evolutionary ... those who believe in language as an adaptation, those who believe it is a by-product of another adaptation, and those who ... On the issue of whether language is best seen as having evolved as an adaptation or as a by product, evolutionary biologist W. ...
Mood disorder
A number of authors have also suggested that mood disorders are an evolutionary adaptation (see also evolutionary psychiatry). ... Progress in Neuro-Psychopharmacology and Biological Psychiatry. 30 (5): 815-826. doi:10.1016/j.pnpbp.2006.01.007. PMID 16647176 ... Nesse R (2000). "Is Depression an Adaptation?" (PDF). Arch. Gen. Psychiatry. 57 (1): 14-20. CiteSeerX 10.1.1.318.2659. doi: ...
Cognitive specialization
2008) argue that the "profound continuity" Charles Darwin noted between human and non-human animals in the biological domain is ... Pinker, S (2003). "Language as an adaptation to the cognitive niche". Studies in the Evolution of Language. 3: 16-37. doi: ... Linguist Noam Chomsky proposed a biological component of language, which he termed Universal Grammar. According to Chomsky, an ... Sugiyama, L. S.; Tooby, J.; Cosmides, L. (2002). "Cross-cultural evidence of cognitive adaptations for social exchange among ...
Eukaryote hybrid genome
Series B, Biological Sciences. 363 (1506): 3047-54. doi:10.1098/rstb.2008.0065. PMC 2607310. PMID 18579480. Fontaine MC, Pease ... In the plant Arabidopsis arenosa some of the alleles conferring adaptation to drought and phytotoxic levels of metal have been ... Biological Sciences. 284 (1856): 20170335. doi:10.1098/rspb.2017.0335. PMC 5474069. PMID 28592669. Pritchard JK, Stephens M, ... Biological Sciences. 283 (1838): 20161493. doi:10.1098/rspb.2016.1493. PMC 5031664. PMID 27629037. David WM, Mitchell DL, ...
Andean goose
Storz, Jay; Hideaki Moriyama (June 2008). "Mechanisms of Hemoglobin Adaptation to High Altitude Hypoxia". High Altitude ... Biological Chemistry Hoppe-Seyler. 368 (12): 1559-1569. doi:10.1515/bchm3.1987.368.2.1559. PMID 3442599. ...
Visual masking
Series B, Biological Sciences. 134 (875): 283-302. Bibcode:1947RSPSB.134..283C. doi:10.1098/rspb.1947.0015. PMID 20292379. ... Crawford BH (March 1947). "Visual adaptation in relation to brief conditioning stimuli". Proceedings of the Royal Society of ...
Gregory Bateson
Urbana, IL: Biological Computer Laboratory, University of Illinois. pp. 97-98, 98-101, 299, 419-420. Bateson, G. (1974). " ... Bateson, G. (1991). "The Moral and Aesthetic Structure of Human Adaptation". In Donaldson, R.E. (ed.). A Sacred Unity: Further ... Bateson, G. (1972). "Effects of Conscious Purpose on Human Adaptation". Steps to an Ecology of Mind: Collected Essays in ... Bateson, G.; von Foerster, Heinz (1974). Conditioning, Adaptation, Learning Model, and Double Bind. Cybernetics of Cybernetics ...
Saccharomyces paradoxus
Leducq, J-B; Charron, G; Samani, P (2014). "Local climatic adaptation in a widespread microorganism". Proceedings of the Royal ... Society B: Biological Sciences. 281 (1777): 20132472. doi:10.1098/rspb.2013.2472. PMC 3896012. PMID 24403328. Liti, G; Carter, ... Accordingly, its biogeography is mostly marked by natural processes like limited migration, glacial refugia and adaptation to ...
Function (biology)
Selected effect theories of biological functions hold that the function of a biological trait is the function that the trait ... Function can be defined in a variety of ways, including as adaptation, as contributing to evolutionary fitness, in animal ... It is not always clear which behavior has contributed to the selection of a trait, as biological traits can have functions, ... From the point of view of natural selection, biological functions exist to contribute to fitness, increasing the chance that an ...
Prehistory of nakedness and clothing
Thus the loss of fur was also a factor in further adaptations, both physical and behavioral, that differentiated humans from ... Giles, James (20 March 2015) [2010]. "Naked love: The evolution of human hairlessness". Biological Theory. 5 (4): 326-336. doi: ... The aquatic ape hypothesis (that hair loss was due to adaptation to an aquatic environment) has been generally discredited by ... Jablonski, N.G.; Chaplin, G. (2010). "Human skin pigmentation as an adaptation to UV radiation". Proceedings of the National ...
Biodiversity loss
... species and biological traits at an alarming rate. This observation led to the question of how such loss of biological ... Otto, Sarah P. (November 21, 2018). "Adaptation, speciation and extinction in the Anthropocene". Proceedings of the Royal ... Management of biological invasion can also be costly. In Australia, the expense to monitor, control, manage, and research ... However, in most cases, the economic returns are far less than the cost caused by biological invasion. Not only have invasive ...
Neanderthal
Stringer, C. (1984). "Human evolution and biological adaptation in the Pleistocene". In Foley, R. (ed.). Hominid evolution and ... Series B, Biological Sciences. 370 (1663): 1-11. doi:10.1098/rstb.2014.0062. PMC 4305163. PMID 25602066. Orban, Guy A; Caruana ... Researchers often explain these features as adaptations to conserve heat in a cold climate, but they may also have been ... Body proportions are usually cited as being "hyperarctic" as adaptations to the cold, because they are similar to those of ...
Dark skin
"Skin Color Adaptation". Human Biological Adaptability: Skin Color as an Adaptation. Palomar. Archived from the original on 18 ... Skin pigmentation is an evolutionary adaptation to various UVR levels around the world. As a consequence there are many health ... but may in fact be a later evolutionary adaptation to tropical rainforest regions. Due to mass migration and increased mobility ... "The distinct morphological phenotypes of Southeast Asian aborigines are shaped by novel mechanisms for adaptation to tropical ...
Mongoloid
Joseph K. So (1980). "Human Biological Adaptation to Arctic and Subarctic Zones". Annual Review of Anthropology. 9: 63-82. doi: ... With the availability of new data due to the development of modern genetics, the concept of races in a biological sense has ... The term is derived from a now-disproven theory of biological race. In the past, other terms such as "Mongolian race", "yellow ... With the rise of modern genetics, the concept of distinct human races in a biological sense has become obsolete. In 2019, the ...
Richard Lewontin
Lewontin criticized traditional neo-Darwinian approaches to adaptation. In his article "Adaptation" in the Italian Enciclopedia ... Lewontin briefly argued for the historical nature of biological causality in "Is Nature Probable or Capricious?". In "Organism ... "Adaptation," Scientific American, vol. 239, (1978) 212-228. Gould, S. J.; Lewontin, R. C. (1979). "The Spandrels of San Marco ... 16 (1, Logic in Biological Investigation): 25-27. doi:10.2307/1293548. JSTOR 1293548. Lewontin, R. C. (1970). "The Units of ...
Light skin
"Skin Color Adaptation". Human Biological Adaptability: Skin Color as an Adaptation. Palomar. Archived from the original on 18 ... "Human Biological Adaptability: Skin Color as an Adaptation". www2.palomar.edu. Post; Daniels Jr, F; Binford Jr, R. T.; et al. ( ... Skin pigmentation is an evolutionary adaptation to the various UV radiation levels around the world. There are health ... This observation indicates that the frequencies may have increased due to continued adaptation to a low light conditions." ...
Insect winter ecology
Biological Reviews 78:181195 Layne JR, Edgar CL and Medwith RE (1999) Cold hardiness of the woolly bear caterpillar ( ... W., Hochachka, Pater (2016). Biochemical adaptation. Princeton University Press. ISBN 978-0691640556. OCLC 938370255. The ... 1995) Biological ice nucleation and its applications. St. Paul, MN: The American Phytopathological Society. Sinclair, Brent ( ... Human Reproduction 15:26-46 Lee RE and Costanzo JP (1998) Biological ice nucleation and ice distribution in cold-hardy ...
Glycolysis
"The Journal of Biological Chemistry. 292 (34): 14250-14257. doi:10.1074/jbc.M117.795294. PMC 5572926. PMID 28634232.. ... This is vital for both homeostatsis in a static environment, and metabolic adaptation to a changing environment or need.[22] ... "The Journal of Biological Chemistry. 280 (4): e3. doi:10.1016/S0021-9258(20)76366-0. PMID 15665335.. ... "The Journal of Biological Chemistry. 249 (24): 7737-7741. doi:10.1016/S0021-9258(19)42029-2. PMID 4372217.. ...
Archaeopteris
Other modern adaptations[edit]. Aside from its woody trunk, Archaeopteris possessed other modern adaptations to light ... Biological Reviews of the Cambridge Philosophical Society. 69 (3): 345-417. doi:10.1111/j.1469-185x.1994.tb01276.x. S2CID ...
Weed control
Biological methods[edit]. A biological weed control regiment can consist of biological control agents, bioherbicides, use of ... Yet another approach is the Harrington Seed Destructor, which is an adaptation of a coal pulverizing cage mill that uses steel ... Several studies provided evidence for the role of invertebrates to the biological control of weeds[13][14] ... Weed control plans typically consist of many methods which are divided into biological, chemical, cultural, and physical/ ...
Triassic-Jurassic extinction event
"Biological Reviews of the Cambridge Philosophical Society. 91 (1): 106-147. doi:10.1111/brv.12161. ISSN 1469-185X. PMID ... Edwin H. Colbert drew parallels between the system of extinction and adaptation between the Triassic-Jurassic and Cretaceous- ... Within his 1958 study recognizing biological turnover between the Triassic and Jurassic, Edwin H. Colbert's 1958 proposal was ... indicating a biological turnover where modern groups of fish started to supplant earlier groups.[5] Conodonts, which were ...
Polymorphism (biology)
It was selected but this doesn't mean it is an adaptation. The reason is that, although it was selected, there was no selection ... Polymorphism is strongly tied to the adaptation of a species to its environment, which may vary in colour, food supply, and ... Polymorphism is common in nature; it is related to biodiversity, genetic variation, and adaptation. Polymorphism usually ...
Culture
Michael Tomasello (1999). "The Human Adaptation for Culture". Annual Review of Anthropology. 28: 509-29. doi:10.1146/annurev. ... biological anthropology, linguistic anthropology, cultural anthropology, and in the United States and Canada, archaeology.[35][ ... and that the basis of culture is found in evolved biological dispositions. ...
Adaptive immune system
"The Journal of Biological Chemistry. 282 (21): 15319-23. doi:10.1074/jbc.R700009200. PMID 17395581.. ... "adaptation" to environmental changes.[citation needed] ... differing in biological properties; each has evolved to handle ... Biological Sciences. 281 (1785): 20140454. doi:10.1098/rspb.2014.0454. PMC 4024302. PMID 24789904.. ...
Hagfish
"Proceedings of the Royal Society B: Biological Sciences. 278 (1721): 3096-101. doi:10.1098/rspb.2010.2784. PMC 3158932. PMID ... It is assumed this is an adaptation to survive predator attacks.[7] The Atlantic hagfish, representative of the subfamily ... The following hagfish and lamprey phylogeny is an adaptation based on the 2006 work by Shigeru Kuratani and Shigehiro Kuraku:[ ... which may be an adaptation to a scavenging lifestyle, allowing them to maximize sporadic opportunities for feeding. From an ...
Neoplasm
Cellular adaptation. Atrophy. Hypertrophy. Hyperplasia. Dysplasia. Metaplasia Squamous. Glandular. Cell death. Necrosis ... List of biological development disorders. *Epidemiology of cancer. *Pleomorphism. References[edit]. .mw-parser-output .reflist{ ...
Fatty acid
... play an important role in biological processes, and in the construction of biological structures (such as cell membranes). ... Raynard RS, Cossins AR (May 1991). "Homeoviscous adaptation and thermal compensation of sodium pump of trout erythrocytes". The ...
মানুষ - উইকিপিডিয়া
Peccei, Jocelyn Scott (২০০১)। "Menopause: Adaptation or epiphenomenon?"। Evolutionary Anthropology। 10 (2): 43-57। ডিওআই: ... Robin, Ashley (1991). Biological Perspectives on Human Pigmentation. Cambridge: Cambridge University Press. ... "Climate change, species-area curves and the extinction crisis"। Philosophical Transactions of the Royal Society B: Biological ... "Human Biological Adaptability; Overview"। Palomar College। ৬ মার্চ ২০১৩ তারিখে মূল থেকে আর্কাইভ করা। সংগ্রহের তারিখ ৬ ...
Muscogee
Biological fathers are important within the family system but must come from another clan than the mother. But, within the clan ... rejecting accommodation with white settlers and adaptation of European-American culture. Although Hawkins personally was never ...
Biological basis of love
It is a suite of adaptations and by-products that arose sometime during the recent evolutionary history of humans.[8] ... The theory of a biological basis of love has been explored by such biological sciences as evolutionary psychology, evolutionary ... Bode and Kushnick undertook a comprehensive review of romantic love from a biological perspective in 2021.[8] They considered ... Based on the content of that review, they proposed a biological definition of romantic love: .mw-parser-output .templatequote{ ...
Novel
... were concerned with technological and biological developments. Industrialization, Darwin's theory of evolution and Marx's ... as well as by adaptation of popular literary classics by the film and television industries. ...
Calmodulin
"The Journal of Biological Chemistry. 271 (2): 761-7. doi:10.1074/jbc.271.2.761. PMID 8557684. S2CID 9746955.. ... Calmodulins play an essential role in plant development and adaptation to environmental stimuli. ... "The Journal of Biological Chemistry. 266 (13): 8050-4. doi:10.1016/S0021-9258(18)92938-8. PMID 1902469.. ... "The Journal of Biological Chemistry. 269 (13): 9912-20. doi:10.1016/S0021-9258(17)36969-7. PMID 8144585.. ...
Small population size
Biological Conservation. 142: 1025-1031. *^ de Villemereuil, Pierre (2019). "Little Adaptive Potential in a Threatened ... Genetic adaptation to fragmented habitat: Over time species evolve to become adapted to their environment. This can lead to ... Fragmented populations also see genetic adaptation. For example, habitat fragmentation has resulted in a shift toward increased ...
Fight-or-flight response
This response is recognised as the first stage of the general adaptation syndrome that regulates stress responses among ... Biological determinism. *Connectionism. *Environmental determinism. *Nature versus nurture. *Psychological nativism. *Social ...
Virgin New Adventures
Adaptations[edit]. Paul Cornell's 1995 novel, Human Nature, as noted above, formed the basis of a two-part episode of the ... a ruthless Iranian soldier accidentally causes a deadly biological agent to be released in the Earth's atmosphere, killing ... In October 2012 a special adaptation of Benny's debut story, Love and War was published with Sylvester McCoy as the Seventh ... Due to the success of what was planned to be a one-off release, Big Finish continued the line with an adaptation of The Highest ...
Algorithm
Tsypkin (1971). Adaptation and learning in automatic systems. Academic Press. p. 54. ISBN 978-0-08-095582-7. .. ... However, algorithms are also implemented by other means, such as in a biological neural network (for example, the human brain ...
Snake
"Snake eyes: New insights into visual adaptations". ScienceDaily. 16 August 2016.. *^ Simões, Bruno F.; et al. (October 2016). " ... Australian Biological Resources Studies, Canberra. *^ Arnold EN (1984). "Evolutionary aspects of tail shedding in lizards and ... Biological Sciences. 271 Suppl 4 (suppl_4): S226-9. doi:10.1098/rsbl.2003.0151. PMC 1810015. PMID 15252991.. ... Jensen B, Moorman AF, Wang T (May 2014). "Structure and function of the hearts of lizards and snakes". Biological Reviews of ...
Leaf
Evolutionary adaptationEdit. Poinsettia bracts are leaves which have evolved red pigmentation in order to attract insects and ... "Proceedings of the Royal Society B: Biological Sciences. 276 (1654): 121-127. doi:10.1098/rspb.2008.0858. PMC 2614250. PMID ... Some species have cryptic adaptations by which they use leaves in avoiding predators. For example, the caterpillars of some ... The shape and structure of leaves vary considerably from species to species of plant, depending largely on their adaptation to ...
ജീവപരിണാമം - വിക്കിപീഡിയ
The growth of biological thought. Harvard. p483: "Adaptation... could no longer be considered a static condition, a product of ... Series B, Biological Sciences. 355 (1403): 1553-1562. doi:10.1098/rstb.2000.0716. PMC 1692896. PMID 11127900.. CS1 maint: ref= ... "Philosophical Transactions of the Royal Society B: Biological Sciences. 361 (1465): 163-171. doi:10.1098/rstb.2005.1712. ISSN ... "Philosophical Transactions of the Royal Society B: Biological Sciences. 353 (1366): 307-314. doi:10.1098/rstb.1998.0211. ISSN ...
Camel
"Proceedings of the Royal Society B: Biological Sciences. 266 (1420): 649-56. doi:10.1098/rspb.1999.0685. PMC 1689826. PMID ... Ecological and behavioral adaptations. Camels do not directly store water in their humps; they are reservoirs of fatty tissue. ... "Camel Adaptations". Wildlife Conservation Society. Archived from the original (Flash) on 26 June 2012. Retrieved 29 November ... Fayed, R. H. "Adaptation of the Camel to Desert environment." Proceedings of the ESARF 11th Annual Conference. Available at:, ...
Climate change in Australia
a b National Climate Change Adaptation Programme Retrieved 2008-07-31 *^ "Climate Adaptation Flagship (Overview)". 1 August ... Biological Conservation, 72, 39-354. *^ Beaumont, L.J., and Hughes, L. (2002) Potential changes in the distributions of ... National Climate Change Adaptation Research Facility Retrieved 2011-07-06 *^ "Climate Change Impacts and Adaptation - Local ... National Climate Change Adaptation Research Facility[edit]. The National Climate Change Adaptation Research Facility (NCCARF) ...
Vine
"Proceedings of the Royal Society B: Biological Sciences. 271 (1552): 2011-2015. doi:10.1098/rspb.2004.2827. JSTOR 4142967. PMC ... It is also an adaptation to life in areas where small patches of fertile soil are adjacent to exposed areas with more sunlight ... "Proceedings of the Royal Society B: Biological Sciences. 282 (1814): 20151379. doi:10.1098/rspb.2015.1379. PMC 4571702. PMID ...
অভিযোজন - উইকিপিডিয়া
Biological organisation. জীবমণ্ডল , বাস্তুতন্ত্র , Biocoenosis , জনসংখ্যা , জীব, Biological system , অঙ্গ , কলা (জীববিজ্ঞান) , ... জীববিজ্ঞানে, অভিযোজন (ইংরেজি:Adaptation) হল কোন জীবের জীবদ্দশায় ভূমিকা রাখা একটি উপস্থিত কর্মসম্পাদনকারী বৈশিষ্ট্য, যা ...
Robert Wise
Wise's adaptation of Michael Crichton's science-fiction thriller, The Andromeda Strain (1971), an anti-biological warfare film ... in an adaptation of Shirley Jackson's novel The Haunting of Hill House.[60] Wise's big-budget adaptation of Richard Rodgers and ... Between Curse and Snatcher, Wise directed Mademoiselle Fifi (1944), an adaptation of two Guy de Maupassant short stories that ... sound and scoring of music for an adaptation.[64] ...
Participatory monitoring
"Biological Conservation. 154: 61-71. doi:10.1016/j.biocon.2011.11.018.. *^ Danielsen, F.; Adrian, T.; Brofeldt, S.; Noordwijk, ... Weathering Uncertainty - Traditional knowledge for climate change assessment and adaptation. United Nations University. ... "Biological Conservation. 169: 258-267. doi:10.1016/j.biocon.2013.11.017.. *^ Sodhi, N.S. and Ehrlich, P.R. (Eds.). 2010. ... 2014). "The eBird enterprise: An integrated approach to development and application of citizen science". Biological ...
Muscogee
Biological fathers are important within the family system but must come from another clan than the mother. But, within the clan ... rejecting accommodation with white settlers and adaptation of European-American culture. Although Hawkins personally was never ...
Moll Flanders
Film, TV, or theatrical adaptations[edit]. *A 1965 film adaptation titled The Amorous Adventures of Moll Flanders starred Kim ... After three children (one dies), Moll learns that her mother-in-law is actually her biological mother, which makes her husband ... A later American adaptation, Moll Flanders (1996), starred Robin Wright Penn as Moll Flanders and Morgan Freeman as Hibble, ... A second British television adaptation, broadcast by ITV in 1996, titled The Fortunes and Misfortunes of Moll Flanders, with ...
Browsing Department of Biological and Medical Psychology by Subject "adaptation"
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WHO HQ Library catalog
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important...
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important ... Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important ... Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important ... Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important ...
Adaptations of Australian animals to cane toads - Wikipedia
Biological Journal of the Linnean Society. 99 (4): 738-759. doi:10.1111/j.1095-8312.2010.01395.x. www.canetoadsinoz.com Cane ... Evolutionary selective adaptations are most likely to occur in native species having lived sympatrically with cane toads over ... One way in which Australian animals have adjusted to the presence of the cane toad is through learned behavioural adaptations. ... Furthermore, the presence of cane toads has induced genetically based behavioural adaptations in this snake species. ...
Biological basis of brain's ability for rapid adaptation revealed
... from detecting an object moving in your direction to finding out what the object is through a phenomenon called adaptation. ... Biological basis of brains ability for rapid adaptation revealed. By ANI Tuesday, November 23, 2010 LONDON - When you detect ... Now, a new study details the biological basis of this ability for rapid adaptation: neurons located at the beginning of the ... The researchers found that the effect of adaptation on the synchrony of neurons in the thalamus was the key element in the ...
By B2A author - Biological Adaptation and Ageing
Cads and dads | The Economist
Promiscuity and fidelity seem to be specific biological adaptations. Their manifestations in men and women are not as different ... Promiscuity and fidelity seem to be specific biological adaptations. Their manifestations in men and women are not as different ... RECEIVED wisdom and biological theory both have it that males are (or, at least, would like to be) more promiscuous than ... As with many biological phenomena-height, for example-propensity for promiscuity in either sex might be expected to be normally ...
Adaptation of a Culturally Relevant Nutrition and Physical Activity Program for Low-Income, Mexican-Origin Parents With Young...
Adiposity, biological markers of disease, and insulin resistance in Mexican American adolescents, 2004-2005. Prev Chronic Dis ... Cultural adaptation of a nutrition education curriculum for Latino families to promote acceptance. J Nutr Educ Behav 2011;43(4 ... Adaptation of a Culturally Relevant Nutrition and Physical Activity Program for Low-Income, Mexican-Origin Parents With Young ... Adaptation of a Culturally Relevant Nutrition and Physical Activity Program for Low-Income, Mexican-Origin Parents With Young ...
PDF] The Problem of Biological Individuality | Semantic Scholar
The aim of this article is to show that there is a real problem of biological individuality, and an urgent need to arbitrate ... but there remains a great deal of controversy about the exact status and definition of a biological individual. Recently some ... There is a real problem of biological individuality, and an urgent need to arbitrate among the current plethora of solutions to ... The major historical developments in theory of organismal adaptation are reviewed, clarifying what adaptation is and what it is ...
Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis
... Nat Genet. 2015 Jan;47(1):57 ... Adaptation, Biological / genetics* * Adolescent * Adult * Bacterial Proteins / genetics * Carrier State / microbiology* * Child ... This list of genes suggests a role in host adaptation for remodeling of regulatory networks and central metabolism, acquisition ... The characterization of genes involved in host adaptation may help in predicting bacterial evolution in patients with cystic ...
School of Biological and Marine Sciences Seminar Series 2020/2021 - University of Plymouth
School of Biological and Marine Sciences Seminar Series 2020/2021 - Archive of events ... Climate change, adaptation and evolution in marine and terrestrial environments. Professor James Crabbe, Wolfson College, ... School of Biological and Marine Sciences Seminar Series 2017/2018 * School of Biological and Marine Sciences Seminar Series ... School of Biological and Marine Sciences Seminar Series 2019/2020 * School of Biological and Marine Sciences Seminar Series ...
Climate Change Adaptation Planning - Brown and Caldwell
Bartter Syndrome: Practice Essentials, Pathophysiology, Etiology
MS-LS4 Biological Evolution: Unity and Diversity | Next Generation Science Standards
LS4.C: Adaptation. *Adaptation by natural selection acting over generations is one important process by which species change ... LS4.C: Adaptation. *Adaptation by natural selection acting over generations is one important process by which species change ... LS4.C: Adaptation. *Adaptation by natural selection acting over generations is one important process by which species change ...
Worm Tolerates Temperature Gradient of 140 Deg F - Biological Strategy - AskNature
Adaptations to environmental extremes by multicellular organisms. International Journal of Astrobiology , 09/07/2007 , Mohammed ... Biological Strategy The Beetles That Scatter "All the Light". White scarab beetles ... Biological Strategy How a Camels Fur Coat Keeps It Cool. Dromedary camel ... Each month, well bring you a selection of compelling updates to this ever-growing library of biological strategies and ...
Projects - School of Biological and Behavioural Sciences
BIONATURE 2014 Call for Papers
Ecological adaptation; Fragmentation and scale effect; Biological invasions and climate change; International conventions on ... Arctic and Antarctic bio-pulse (Resource exploitation and large-scale eco- perturbations; Under-ice ecosystems; Adaptation and ... Bioenergy is renewable energy derived from biological sources, to be used for heat, electricity, or vehicle fuel. Biofuel ... Biological pollution (invasion); Pollution prevention, control and engineering); Natural and man-made disasters ...
Molecular adaptations of rod opsins in deep-sea fish - Fingerprint - the UWA Profiles and Research Repository
Bartter Syndrome Medication: Potassium Supplements, Diuretics, Potassium-Sparing, ACE Inhibitors, NSAIDs
NIOSHTIC-2 Search Results - Full View
Age-factors; Biological-factors; Injuries; Muscle-function; Muscle-physiology; Muscle-stress; Muscular-disorders; ... Skeletal muscle injury versus adaptation with aging: novel insights on perplexing paradigms. ... current evidence supports a model of muscle adaptation and/or maladaptation, distinct from overt injury, in which myofiber ... muscle adaptation; myofiber degeneration; myofiber regeneration; inflammation ...
Management of chemical and biological risks in agri-food chain
Paper presents diverse modes of governance of chemical and biological risks in agri-food sector, assesses their efficiency, ... high adaptation and compliance costs; unequal norms, implementing capability, policies and private strategies; public failures ... "Management of chemical and biological risks in agri-food chain," MPRA Paper 30905, University Library of Munich, Germany. ... Paper presents diverse modes of governance of chemical and biological risks in agri-food sector, assesses their efficiency, ...
Faculty - Biological Sciences | Binghamton University
Novel alleles gained during the Beringian isolation period | Scientific Reports
Choin, J. et al. Genomic insights into population history and biological adaptation in Oceania. Nature 592, 583-589. https:// ... Jablonski, N. G. & Chaplin, G. Human skin pigmentation as an adaptation to UV radiation. Proc. Natl. Acad. Sci. 107, 8962-8968 ... Finally, to characterize biological systems and pathways affected by selected GSPs, we compiled a list of genes with Beringian ... Amongst the biological pathways impacted by non-synonymous GSPs, the categories with the greatest number of genes include ...
Genetics and Genomics of Soybean | Ebook | Ellibs Ebookstore
Bioenergetics
Dengue Emergence and Adaptation to Peridomestic Mosquitoes - Volume 10, Number 10-October 2004 - Emerging Infectious Diseases...
Moncayo is an assistant professor in the Department of Biological Sciences at Ohio Northern University in Ada, Ohio. He is a ... Our study examined the extent of endemic DENV adaptation to peridomestic vectors. If this adaptation is species-specific, then ... Dengue Emergence and Adaptation to Peridomestic Mosquitoes. Emerging Infectious Diseases. 2004;10(10):1790-1796. doi:10.3201/ ... Phylogenetic studies suggest that the DENV E protein may be important in the adaptation to urban vectors (11). In particular, ...
Find a PhD Supervisor | School of Biological Sciences | Queen's University Belfast
Natural selection, adaptation, extinctions, adaptive radiation, climate, macroecology, reptiles, amphibians Dr Daniel Pincheira ... School of Biological Sciences. Queens University Belfast. School of Biological Sciences. 19 Chlorine Gardens. Belfast BT9 5DL ... Development of biological and chemical approaches for the removal and/or recovery of high-value compounds from waste eg. ... The aim is to build a coherent theory of what life essentially is and use this to better inform biological science `from ...
SciencesOrganismsEvolutionPhysiologicalDiversityMicrobial2022SpeciesEcologicalPopulationsSpecific adaptationsEcology2021RegulationSalk InstituImpacts of climate changeGeneticHumansEnvironmentsPsychiatryProcessesInteractionsGenomeEcosystemsBehaviouralGenesFunctionalBiodiversityResearchPrinciplesLocal adaptationBiologyVulnerabilityConservationSurviveAgri-foodMarine BiologicalRegimesLaboratoryEnvironmentMechanismStudyAbstractInterventionsAffectBrain'sFreshwaterNeuronsMaladaptationTransboundaryBehaviorBasic biologicalHumanLimitsTheorySurvival
Sciences15
- It is claimed that a debate on biological individuality that seeks to account for diverse practices in the biological sciences should be broadened to include and give prominence to questions about uniqueness and temporality. (semanticscholar.org)
- Applications are invited from candidates with, or expecting to be awarded, at least an upper-second class bachelors degree (or equivalent qualification) in biological sciences (or similar). (qmul.ac.uk)
- A general equation for the role of additive, dominance, and epistatic components of fitness in determining the rate of change in population fitness is given and claims that this law should hold the same position among the biological sciences as the second law of thermodynamics in physical sciences. (semanticscholar.org)
- Dr Frances Sussmilch is an ARC DECRA Fellow in Biological Sciences at the School of Natural Sciences. (edu.au)
- Go beyond the classroom walls and enter into active laboratory and field research in biological and environmental sciences. (mbl.edu)
- Immerse your students in active and ongoing research conducted by MBL research scientists that tackles the major questions in basic biological sciences. (mbl.edu)
- Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 63 (Supple). (pitt.edu)
- Philosophical Transactions of the Royal Society B: Biological Sciences 2019, 374 (1770), 20180110. (ncl.ac.uk)
- Publishing their findings in the journal Proceedings Of The Royal Society B: Biological Sciences, the researchers found that by the end of the heat stress exposure, all of the least-tolerant corals were dead, while the most-tolerant remained alive. (eurekalert.org)
- Proceedings Of The Royal Society B: Biological Sciences , 289 (1981). (eurekalert.org)
- A membership society whose goal is to advance and to diffuse knowledge of organic evolution and other broad biological principles so as to enhance the conceptual unification of the biological sciences. (amnat.org)
- The theory of a biological basis of love has been explored by such biological sciences as evolutionary psychology , evolutionary biology , anthropology and neuroscience . (wikipedia.org)
- Liberal Arts Biology covers fundamental principles of biological sciences at a level for non-science majors. (luc.edu)
- To allow you to explore your various options, here's a list of some of currently available PhD opportunities across the School of Biological Sciences. (reading.ac.uk)
- Saudi journal of biological sciences 2020 6 0. (cdc.gov)
Organisms10
- Organisms or biological individuals? (semanticscholar.org)
- In the ocean, an organism's weight is supported by the water, and some organisms have additional adaptations that help them remain buoyant such as swim bladders in fish. (hawaii.edu)
- A diverse instructional faculty will offer participants the opportunity to study a wide range of Antarctic organisms (bacteria, algae, invertebrates, fish), using different levels of biological analysis (spanning molecular biology, physiological ecology, species diversity, and evolution). (scar.org)
- Clarification Statement: Emphasis is on using data to provide evidence for how specific biotic and abiotic differences in ecosystems (such as ranges of seasonal temperature, long-term climate change, acidity, light, geographic barriers, or evolution of other organisms) contribute to a change in gene frequency over time, leading to adaptation of populations. (nextgenscience.org)
- Natural selection leads to adaptation, that is, to a population dominated by organisms that are anatomically, behaviorally, and physiologically well suited to survive and reproduce in a specific environment. (nextgenscience.org)
- These will essentially further enforce the material taught during the lectures i.e. range of diversity within and between animal groups, their defining characteristics, and the functional perspective of adaptations - asking the question 'how do the adaptations we see in the organisms in front of us fit to life styles of the animals concerned? (exeter.ac.uk)
- Understanding of how organisms can survive in a variety of environments is the study of small-scale adaptation to local conditions. (uvm.edu)
- Emphasize that organisms have adaptations that affect how well they survive in a specific environment. (teacherspayteachers.com)
- Over millions of years of evolution, organisms on earth have developed and perfected complex adaptations that allow them to survive and eventually thrive under specific environmental conditions. (uctv.tv)
- Newly married couples, for example, experience a period of adjustment analogous to the way biological organisms in an ecosystem adjust to the introduction of a new species. (byu.edu)
Evolution16
- The characterization of genes involved in host adaptation may help in predicting bacterial evolution in patients with cystic fibrosis and in the design of future intervention strategies. (nih.gov)
- How a lower‐level, bottom‐up evolutionary framework can be used to understand biological complexity involved in the origin of cellular life, early eukaryotic evolution, sexual life cycles and multicellular development is demonstrated. (semanticscholar.org)
- This biological adaptation is also a mechanism of rapid evolution, Pierce says. (phys.org)
- In recent years, evolutionary theorists have come to recognize that the reductionist, individualist, gene-centered approach to evolution cannot sufficiently account for the emergence of complex biological systems over time. (uchicago.edu)
- Adaptation and evolution of biological materials. (mpg.de)
- To understand that it's just a biological adaptation of evolution and that's it. (englishclub.com)
- It's an adaptation, a product of natural selection in the evolution of the human species. (edge.org)
- The module complements other biological modules in Stage 1, Ecology and Conservation, Evolution, Physiology and Marine Biology, and provides a foundation for Stage 2 modules at the Penryn campus. (exeter.ac.uk)
- Define how ecophysiological processes structure microbial communities, influence their adaptation and evolution, and affect their detection on other planets. (nasa.gov)
- Designed to introduce students to general biological principles, with a focus on ecology and evolution. (gettysburg.edu)
- A biological anthropologist and paleobiologist, she studies the evolution of adaptations to the environment in Old World primates including humans. (edge.org)
- Her research on the evolution of human adaptations to the environment centers on the evolution of human skin and skin pigmentation, and includes an active field project examining the relationship between skin pigmentation and vitamin D production. (edge.org)
- A recent paper in the journal Evolution by ISU theoretical biologist Stephen Proulx has generated interest in the biological community. (iastate.edu)
- These mutations are the evolution strategies of the virus for host adaptation, and they might impede the efficacy of the current therapeutics and the accuracy of the diagnostic tests. (news-medical.net)
- Students will be able to demonstrate an understanding of human genetics, patterns of human heredity, the mechanisms of biological evolution, nature/nurture debate, primate taxonomy and behavior, and early human fossil evidence and interpretation. (luc.edu)
- And the claim that complex adaptations can evolve independently multiple times (i.e., convergent evolution) collapses on close examination due to the implausibility of their appearing through undirected processes even once. (evolutionnews.org)
Physiological6
- It is suggested that the combination of an evolutionary and a physiological perspective will enable biologists and philosophers to supply an account of biological individuality that will be both more comprehensive and more in accordance with scientific practices. (semanticscholar.org)
- Biological and physiological role of PPARγ in the body has been established. (kiev.ua)
- Besides these molecular (such as oxidative stress tolerance), physiological/anatomical (such as chemical protection, horns and antlers) or lifestyle (such as arboreality) adaptations that reduce mortality risk, the organization of activity time budgets should be particularly important in shaping the variety of life histories observed in the wild. (frontiersin.org)
- Here, we develop and apply a new generic modelling approach (AdaptR) that incorporates adaptive capacity through physiological limits, phenotypic plasticity, evolutionary adaptation and dispersal into a species distribution modelling framework. (monash.edu)
- Demonstrate a conceptual understanding of the adaptation and diversity of microbial life on Earth and their physiological role in key biological processes. (bangor.ac.uk)
- physiological Behaioral adaptations. (edu.sa)
Diversity15
- Millet practices what she proses, too-she works at the Center for Biological Diversity . (yesmagazine.org)
- Local adaptation plays an important role in shaping diversity in species with low gene flow. (uni-hamburg.de)
- Under the Post 2020 Global Biodiversity Framework, the Convention of Biological Diversity is planning to expand by at least 30% the protection of areas of land and sea of global relevance for biodiversity and its contribution to people. (edu.au)
- Investigate the role of adaptations in this theory and the diversity of species it can produce. (nsw.gov.au)
- Discover this theory's role in creating the incredible biological diversity present in our environment. (nsw.gov.au)
- Today they offer insight into adaptation to climate change, and they share techniques that support nutritional and biological diversity. (slowfood.com)
- While methane is emitted through rice cultivation, the traditional genetic diversity of rice plants is preserved here at the same time, which can form the basis for future land use adaptations. (ufz.de)
- First term field trips to a range of habitats will allow you to study some of this diversity yourself, focusing on animal function and adaptations to different environments. (exeter.ac.uk)
- Field trips will provide you with the opportunity to further develop your understanding of animal diversity by focusing on animal function and adaptations to differing environments and ecosystems. (exeter.ac.uk)
- In practical classes you will be exposed to animal diversity concentrating on function and adaptation to environments and ecosystems. (exeter.ac.uk)
- This paper demonstrates the power of biophysical modeling of population diversity for better understanding genome-environment interactions in biological phenomenon. (scirp.org)
- We assert that the stability of whole genome adaptation is reflected in the frequencies of maintained diversity in these common variants (SNPs) for a population in its environment. (scirp.org)
- Although more data on the effectiveness of climate change adaptation for species conservation are required, the diversity of examples reviewed suggests that climate change adaptation can successfully reduce negative impacts of, or enhance positive responses to, climate change. (bto.org)
- Myosin motor domains perform an extraordinary diversity of biological functions despite sharing a common mechanochemical cycle. (elifesciences.org)
- Prior to becoming an academic, he served as Assistant Secretary of State for Public Affairs for the State of Wisconsin and worked in the non-governmental sector for twenty years, including as Executive Director of the Pacific Center for International Studies, a think-tank that focused on implementation of international wildlife treaty regimes, including the Convention on Biological Diversity and International Convention for the Regulation of Whaling. (middlebury.edu)
Microbial3
- 1989. Microbial adaptation to degradation of hydrocarbons in polluted and unpolluted groundwater. (cdc.gov)
- Adaptation of a microbial community to demand-oriented biological methanation. (mpg.de)
- Our long-term goals emphasize the utilization of mass spectrometry-based proteomics to fundamentally understand differential microbial adaptation and survival strategies and to integrate a novel systems biology platform for investigation of diverse biological systems, defining functional mechanisms of cellular regulation and pathogenesis. (uoguelph.ca)
20221
- 2022). Within-population variability in coral heat tolerance indicates climate adaptation potential . (eurekalert.org)
Species15
- Biological species have been treated traditionally as spatiotemporally unrestricted classes. (semanticscholar.org)
- This is causing impacts on species in all biomes, across many phyla, and all levels of biological complexity. (plymouth.ac.uk)
- Adaptation by natural selection acting over generations is one important process by which species change over time in response to changes in environmental conditions. (nextgenscience.org)
- The adaptation of members of the Caldicellulosiruptor genus to higher sugar concentrations established that the ability to develop improved strains via ALE is species dependent, with C. owensensis adapted to grow on 80 g/L, whereas C. kristjanssonii could only be adapted to 30 g/L glucose. (biomedcentral.com)
- To solve it, researchers at McGill University and the University of British Columbia synthesized more than 125 studies testing local adaptation in over 100 species. (amnat.org)
- The authors say more direct tests of what drives local adaptation, especially studies of positive interactions and tropical species, are needed before we know the real scope of local adaptation to interactions. (amnat.org)
- A daptation to local conditions can increase species' geographic distributions and rates of diversification, but which components of the environment commonly drive local adaptation-particularly the importance of biotic interactions-is unclear. (amnat.org)
- Adaptation is a biological process where ALL species adapt to changing environments in order to survive. (janethull.com)
- A research team led by biologists at Tufts University has found two genes that may allow some insect species to survive climate change by adjusting their biological annual clocks, while others succumb. (nsf.gov)
- Topics include adaptation, nutrient cycling and energy flow, population growth and species interactions, Mendelian and population genetics, speciation, and the history of life. (gettysburg.edu)
- By focusing on a single species, I have been able to integrate biological processes across the scales from the molecular to the community. (uvm.edu)
- In this first quantitative global assessment of biodiversity conservation interventions for climate change adaptation, we identified 77 peer-reviewed studies, including 443 cases describing the response of individual species' populations or assemblages to particular interventions, whilst also accounting for responses to climate change or particular climatic variables. (bto.org)
- The impacts of climate change are seen across all elements of the natural world, from the timing of biological events to species' interactions, distributions and population sizes. (bto.org)
- Conservation interventions can reduce these impacts by supporting climate change adaptation - interventions to reduce species' exposure or vulnerability to climate change, or enhance the species' capacity to adapt to climatic changes. (bto.org)
- This course explores the study of the biological history of the human species, from its emergence through the establishment of food-producing societies. (luc.edu)
Ecological2
- She applied theoretical perspectives of social change and futures thinking approaches, to understand how ecological change is perceived and anticipated, influencing adaptation options in Australia, Colombia, and South Africa. (edu.au)
- I could be talking about non-fiction pieces I've written - about storms, trees, adaptation and vast ecological systems. (griffithreview.com)
Populations6
- We compared genetic patterns between two groups of populations that had experienced distinct hatchery rearing environments to identify specific outlier locations in the genome that may be related to hatchery adaptation. (purdue.edu)
- However, significant changes in B. pertussis populations have been observed after the introduction of vaccinations, suggesting a role for pathogen adaptation in the persistence and resurgence of pertussis. (cambridge.org)
- Furthermore, current evidence supports a model of muscle adaptation and/or maladaptation, distinct from overt injury, in which myofiber degeneration and inflammation do not contribute as significantly as once reported even in aged populations. (cdc.gov)
- Evolutionary adaptation relies on recombination and spontaneous mutagenesis to constantly introduce variation into populations, upon which natural selection can act. (elifesciences.org)
- The workshop focused on research needed for characterizing exposures to nanomaterials among workers, other populations, and environments by measuring and modeling exposure levels, and by monitoring indicators of biological responses through the product life of a nanomaterial. (cdc.gov)
- They should provide new insights, at different geographic scales (in the major European oceans, seas and inland waters) and different climate change scenarios, on how climate-induced changes may affect important biological processes (including, reproductive success, population dynamics, migration patterns, interactions between fish populations, etc. (europa.eu)
Specific adaptations1
- Low mortality rate is often associated with slow life history, and so far, has mainly been assessed through examinations of specific adaptations and lifestyles that limit mortality risk. (frontiersin.org)
Ecology2
- Students will be able to demonstrate an understanding of basic biological principles (heredity, physiology, evolutionary mechanisms, adaptation, ecology) in the context of their application to the human condition, as well as the role of cultural behavior in defining the distinctiveness of that condition. (luc.edu)
- Our identities are part of a social ecology-a complex system of adaptation and accommodation that occurs in all living systems, including human relationships. (byu.edu)
20212
- Luckily for the Navy, the pandemic seems likely to remain an unparalleled test bed for biological threat mitigation measures until at least the end of 2021. (defensenews.com)
- Bode and Kushnick undertook a comprehensive review of romantic love from a biological perspective in 2021. (wikipedia.org)
Regulation2
Salk Institu1
- 1 Computational Neurobiology Laboratory, Salk Institute for Biological Studies, United States. (nih.gov)
Impacts of climate change1
- Having an overview of the potential impacts of climate change on the Mauritian Sugarcane Industry, its effect can be reduced by formulating the right mitigation and adaptation strategies. (ukessays.com)
Genetic4
- For both of these questions, we also wanted to know which specific genes were involved in potential genetic adaptation. (purdue.edu)
- Previous research has found that genetic adaptation to the hatchery environment, a process sometimes referred to as domestication selection, can occur in as little as one generation. (purdue.edu)
- While both structural colour and transparency have been analysed in great detail by optical physicists, we are now making headway in uncovering the genetic and cell biological basis for these phenomena. (plymouth.ac.uk)
- Adaptation in marine invasion: a genetic perspective. (marinespecies.org)
Humans2
- It is a suite of adaptations and by-products that arose sometime during the recent evolutionary history of humans. (wikipedia.org)
- The resilience of living humans as embodiments of the genome allows for the adaptation of groups to new or changing environments. (scirp.org)
Environments6
- More fundamentally these beneficial microbes may represent a novel evolutionary resource - a 'horizontal gene pool', a reservoir of adaptations that insects can draw from when they adapt to new environments. (qmul.ac.uk)
- The emphasis of the Antarctic Biology Course is on integrative biology, with laboratory- and field-based projects focused on adaptations to extreme polar environments. (scar.org)
- Nevertheless, local adaptation was neither more common nor stronger when biotic interactions were left intact, either between experimental treatments within studies (control vs. biotic interactions experimentally manipulated) or between studies that used natural vs. biotically-altered transplant environments. (amnat.org)
- Our results suggest that biotic interactions often fail to drive local adaptation even though they strongly affect fitness, perhaps because temperate biotic environments are unpredictable at the spatiotemporal scales required for local adaptation. (amnat.org)
- Adaptation is a good thing because this allows all plants and animals to keep living when their environments change. (janethull.com)
- As a living information and communications system, the genome encodes patterns in single nucleotide polymorphisms (SNPs) reflecting human adaptation that optimizes population survival in differing environments. (scirp.org)
Psychiatry2
Processes3
- Following the Turkish adaptation processes, the validity and reliability of the scale were examined with a pilot study. (hindawi.com)
- The findings can inform future-oriented practices to assess and implement processes of adaptation and address the transformational challenges to build resilient, just futures for nature and people. (edu.au)
- The central question in the learning trajectory Human Biology is what are the molecular and cellular bases of biological processes underlying human health and disease? (ru.nl)
Interactions10
- I thought for sure local adaptation to interactions was widespread and we just needed a meta-analysis to show it. (amnat.org)
- The authors found frequent local adaptation across studies and that negative interactions like being eaten or outcompeted strongly reduced performance. (amnat.org)
- Nevertheless, local adaptation was not stronger or more common when experiments left interactions intact. (amnat.org)
- So why don't interactions drive local adaptation even though they affect fitness? (amnat.org)
- When the authors analyzed tropical data separately a stronger signal of local adaptation to interactions emerged. (amnat.org)
- It doesn't explain why interactions don't drive local adaptation more often in temperate ecosystems, but it is intriguing evidence that interactions might be more evolutionarily important in the tropics," says Hargreaves. (amnat.org)
- if this is common we expect transplant experiments to detect more frequent and stronger local adaptation when biotic interactions are left intact. (amnat.org)
- Overall, local adaptation was common and biotic interactions affected fitness. (amnat.org)
- However, the effect of ameliorating negative interactions varied with latitude, suggesting that interactions may promote local adaptation more often in tropical vs. temperate ecosystems, though few tropical studies were available to test this. (amnat.org)
- In contrast, very little is known about their adaptation strategies in the mosquito vector, possibly due to the experimental challenges encountered while studying vector-parasite interactions. (biorxiv.org)
Genome3
- There is something special about relatedness caused by common ancestry, in contrast with the other mechanisms that may lead to individuals being genetically related, because it unites the interests of genes across the genome, allowing complex, multigenic adaptations to evolve. (semanticscholar.org)
- We consider adaptation to be the dynamic process of modifying expressions of the genome towards optimizing the survivability of a group that remains in a particular environment. (scirp.org)
- With the publication of the virus genome information, Sino Biological has developed several research tools to support the study of virus biology. (news-medical.net)
Ecosystems1
- This study identified 77 peer-reviewed publications describing the degree of success observed for climate change adaptation interventions in terrestrial and freshwater ecosystems. (bto.org)
Behavioural3
- One way in which Australian animals have adjusted to the presence of the cane toad is through learned behavioural adaptations. (wikipedia.org)
- Cognitive deficits in schizophrenia: A model-based functional imaging study on working memory and flexible behavioural adaptation. (mpg.de)
- The time of melatonin onset under dim light (DLMO) and the time of the minimum core body temperature (CBT) are important commonly used markers of the circadian clock 4 .Misalignment between the biological clock and behavioural rhythms not only induces sleep disturbances and daytime sleepiness, but can also result in desynchronization of internal rhythms (for example when comparing the central clock to peripheral clocks) 5 . (nature.com)
Genes2
- This list of genes suggests a role in host adaptation for remodeling of regulatory networks and central metabolism, acquisition of antibiotic resistance and loss of extracellular virulence factors. (nih.gov)
- Analysis and summary of the current concept of biological role of nuclear peroxisome proliferator-activated receptor gamma (PPARγ) in the body, that is a transcription factor, simulating the expression of target genes that regulate different chains of adipogenesis, thermogenesis, energy homeostasis, providing balance of glucose and sensitivity of cells to insulin, secretion of adipokines, anti-inflammatory, and anti-fibrotic effects. (kiev.ua)
Functional2
- In this article we fixed on generalisation of data on the structure and functional peculiarities of PPARγ, since we provided the description of biological role of PPARα and PPARβ/δ in the previous issues of this journal (Current topics of toxicology 2016, No. 2 and No. 3). (kiev.ua)
- The emphasis will be on defining the key characteristics of the main phylogenetic groups and understanding adaptations from a functional perspective. (exeter.ac.uk)
Biodiversity1
- The first quantitative global assessment of biodiversity conservation interventions for climate change adaptation has been undertaken, led by BTO researchers. (bto.org)
Research16
- Adaptation of a culturally relevant obesity prevention program involved qualitative research to tailor key obesity prevention messages, pilot testing and implementation of key messages and activities at family nights, and continual modification to incorporate culturally innovative elements. (cdc.gov)
- The newly established joint program between the Marine Biological Laboratory (MBL) and the University of Chicago (UChicago) leverages the unique partnership between two leading research institutions and combines the best of both worlds - access to a collaborative and expansive research environment that spans the scales of biological discovery at the MBL in Woods Hole, MA and the first-class resources of the University of Chicago. (mbl.edu)
- The High School Science Discovery Program puts the tools and technology of modern biological research in the hands of your students, allowing them to discover their inner scientists. (mbl.edu)
- The MBL convenes biologists from around the world to collaborate and conduct research, advancing our mission of biological discovery. (mbl.edu)
- In the research unit „Molecular Evolutionary Biology", we investigate adaptation mechanisms to abiotic and biotic factors in arthropods with state-of-the-art molecular biological, biochemical, genetical and bioinformatical methods. (uni-hamburg.de)
- The research examines the cultural, political, and historical contexts framing climate adaptation narratives in these countries and how such narratives influence the implementation of adaptation. (edu.au)
- [3] Miller described evolutionary psychology as a starting place for further research: "Cognitive neuroscience could try to localize courtship adaptations in the brain. (wikipedia.org)
- Government of Mauritius should play a central role in the development of an adaptation strategy for the sugarcane sector pertaining to policy formulation, research and development, fund disbursement, role of institutions among others. (ukessays.com)
- The objectives of NIOSH, NSET, and other partners were to review the state-of-the-science, identify critical gaps, and inform further development and adaptation of the interagency research strategy as appropriate. (cdc.gov)
- Organizing workshops to inform further development and adaptation of the inter-agency strategy as appropriate in their research categories is one of the coordinating agency roles. (cdc.gov)
- Proulx's research showed how the process of adaptation can play a role in generating organismal complexity. (iastate.edu)
- Biological research - why I study spiders. (uvm.edu)
- By watching a slideshow, reading about the rainforest, and completing some QR code research on rainforest animals and their adaptations. (teacherspayteachers.com)
- Second, even though research on climate adaptation and resilience is expanding rapidly across disciplines, adaptation is still largely treated as a local matter. (thefreelibrary.com)
- This course examines the history of the concept of the biological race, the emergence, and the role of scientific racism, as well as the current scientific research objectives and methodologies. (luc.edu)
- Cultural Adaptation of Terms Aids Study of Adverse Events Research from Italy indicates that terminology used in validated questionnaires for patient-reported outcomes should account for the social and cultural contexts of the countries involved. (medscape.com)
Principles2
- Drawing on both biological and cultural approaches, the authors first cover basic principles of cultural anthropology, environmental studies, and human biological adaptations to the environment. (rowman.com)
- In previous articles, I have described how engineering principles better explain adaptation than does evolutionary theory ( here , here , here , here ). (evolutionnews.org)
Local adaptation3
- A daption to local conditions drives biological diversification, but what drives local adaptation? (amnat.org)
- Local adaptation influences many biological levels, from phenotype to genotype, as well as. (uni-hamburg.de)
- We identify where local adaptation is likely to occur and apply sensitivity analyses to identify the critical factors of interest when parameters are uncertain. (monash.edu)
Biology3
- Synthetic Biology Artificial Life (AL) is the enterprise of understanding biology by constructing biological phenomena out of artificial components, rather than breaking natural life forms down into their component parts. (textfiles.com)
- We are interested in characterizing the mechanisms of pathogenesis, adaptation, and survival in fungal and bacterial microbes from a systems biology perspective through mass spectrometry-based quantitative proteomics. (uoguelph.ca)
- Learning Dynamics from Large Biological Data Sets: Machine Learning Meets Systems Biology. (naturalgenesis.net)
Vulnerability2
- As this Article explains, the adaptation finance gap is problematic not only for the directly impacted communities, but also for international society as a whole since climate vulnerability in one part of the world could in some cases compromise resilience in the rest of the world. (thefreelibrary.com)
- From 2010 until 2015, Mach co-directed the scientific activities of Working Group II of the Intergovernmental Panel on Climate Change, which focuses on impacts, adaptation, and vulnerability. (middlebury.edu)
Conservation1
- This seminar will discuss the narratives of adaptation shaping conservation policies in the three countries, documenting the diverse understandings of adaptation and expectations for managing protected areas under climate change. (edu.au)
Survive2
- It is assumed this is an adaptation to survive predator attacks. (wikipedia.org)
- Students will love learning about rainforest animals and plants and the adaptations they have to survive in the tropical rainforest habitat. (teacherspayteachers.com)
Agri-food2
- Paper presents diverse modes of governance of chemical and biological risks in agri-food sector, assesses their efficiency, complementarities, and challenges, and suggests recommendations for public policies improvement. (repec.org)
- Management of chemical and biological risks in agri-food chain ," MPRA Paper 30905, University Library of Munich, Germany. (repec.org)
Marine Biological1
- We welcome you to visit us and experience the Marine Biological Laboratory for yourself! (mbl.edu)
Regimes1
- Global Public Goods: The Climate-Security Nexus 1059 V. THE LAW AND GOVERNANCE OF MULTI-LEVEL CLIMATE 1062 ADAPTATION: A PROPOSED FRAMEWORK A. Treaty Regimes 1062 B. General International Law 1065 C. Enforcement 1067 D. Risks of Overreach 1069 VI. (thefreelibrary.com)
Laboratory3
- In this study, we directly measure how the fitness landscape neighborhood changes during laboratory adaptation. (elifesciences.org)
- Laboratory emphasizes the experimental nature of biological investigation. (gettysburg.edu)
- Dimitri Deheyn unveils how his laboratory is working to understand and replicate these highly refined biological properties for development of sustainable and economically valuable technologies. (uctv.tv)
Environment7
- Blending classic scholarship with exciting new developments in the discipline, Biological Psychology offers a fresh perspective on the brain's interaction with its environment. (oup.com)
- Scientists believe the evolutionary adaptation of four limbs likely began in an aquatic environment among a group called the lobe-finned fishes. (hawaii.edu)
- This is evidenced by adaptation to stimulus parameters in sensory coding, and in learning of an up-to-date model of the environment at the behavioral level. (nih.gov)
- This approach views biological adaptation as primarily occurring through internal mechanisms (the ability to actively sense the environment and adapt) rather than external influence [natural selection]. (thebereancall.org)
- The Wetland plants vary a lot with respect to their size, biological cycle and adaptations to wetland environment. (nmp-zak.org)
- Address climate change adaptation, design of habitat networks and agri-environment schemes. (reading.ac.uk)
- Adaptation of modern biomedical technology to the study of sleep in the natural environment was reported. (cdc.gov)
Mechanism3
- The biological function of a flower is to facilitate reproduction, usually by providing a mechanism for the union of sperm with eggs . (wikipedia.org)
- Biological adaptation is a powerful mechanism that makes many disorders hard to combat. (ijcai.org)
- Adaptation is a result of brilliant biological engineering rather than trial-and-error death and survival, which flips the mechanism of adaptation completely on its head. (thebereancall.org)
Study8
- Now, a new study details the biological basis of this ability for rapid adaptation: neurons located at the beginning of the brain's sensory information pathway that changes their level of simultaneous firing. (gaeatimes.com)
- The purpose of th study is adaptation of the early learning observation and rating scale-teacher's form, developed by Coleman, West, and Gillis, to Turkish and the Turkish culture and evaluation of the causality relations between the learning domains through Path analysis in the Turkish sample. (hindawi.com)
- In this study, the effectiveness of agronomic adaptation options on the rainfed rice yield gap was evaluated for the baseline period (1981-2005) and two future periods (2016-2040 and 2026-2050) for India by using bias-corrected RegCM4 output and the Decision Support System for Agrotechnology Transfer (DSSAT) model. (iwaponline.com)
- In this paper we study steering such adaptation through sequential planning. (ijcai.org)
- How a brilliant-green sea slug manages to live for months at a time "feeding" on sunlight, like a plant, is clarified in a recent study published in The Biological Bulletin . (phys.org)
- For decades, music researchers have more or less settled into two camps: those who believe their subject of study is a biological adaptation, and those who believe it's a cultural invention. (discovermagazine.com)
- Predictive studies play a crucial role in the study of biological invasions of terrestrial plants under possible climate change scenarios. (cakex.org)
- Mathematical models offer a unique tool to study such complex biological systems, and have been extensively employed in malaria epidemiology. (biorxiv.org)
Abstract1
- Analytical review of scientific publications was performed using abstract databases of scientific libraries and text database of methodological and biological publications PubMed. (kiev.ua)
Interventions1
- The effective monitoring and evaluation of adaptation interventions is required to improve this evidence-base for future decision-making. (bto.org)
Affect2
- These changes to the distribution of fitness effects can affect both the rate of adaptation and the accumulation of deleterious mutations. (elifesciences.org)
- For example, demographic characteristics may affect energy investments among biological traits such as growth, reproduction, and somatic maintenance. (frontiersin.org)
Brain's1
- Your brain's ability to rapidly switch from detecting an object moving in your direction to finding out what the object is through a phenomenon called adaptation. (gaeatimes.com)
Freshwater1
- Ensuring sufficient preparedness and quick adaptation capacity of European marine and freshwater fisheries and aquaculture sectors to potential threats and opportunities due to climate change might be decisive for the long term sustainability of the two sectors, as well as for guaranteeing to European consumers and societies an acceptable degree of self-sufficiency of seafood supplies. (europa.eu)
Neurons1
- The researchers found that the effect of adaptation on the synchrony of neurons in the thalamus was the key element in the shift between sensory input detection and discrimination. (gaeatimes.com)
Maladaptation2
- THE ADAPTATION CHALLENGE 1033 A. Optimal Adaptation vs. Maladaptation 1033 B. The Problem of Externalities and Coordination 1034 C. Multi-Level Public Goods 1037 D. Overcoming Externalities 1039 III. (thefreelibrary.com)
- Consequently, positive international externalities of optimal adaptation (and negative externalities of maladaptation) are overlooked in the literature. (thefreelibrary.com)
Transboundary1
- FINDING THE DIVIDING LINE 1052 A. Adaptation as a Pure Domestic Public Good 1052 B. Adaptation as a Transboundary or a Global Public Good 1055 1. (thefreelibrary.com)
Behavior3
- We show that the framework can be used to steer a biological entity modeled via a complex signaling pathway network that has numerous feedback loops that operate at different rates and have hard-to-understand aggregate behavior. (ijcai.org)
- This course examines the possible biological bases of modern human behavior, from a strong scientific and multi-disciplinary perspective. (luc.edu)
- Physical Constraints in Biological Collective Behavior. (naturalgenesis.net)
Basic biological1
- We suspected there might be a basic biological principle of how our brain works that contributes to this phenomenon, called emotional adaptation," Sharot said. (scientificamerican.com)
Human6
- It is concluded that as the authors have come to better understand human adaptation, its complexities have been further revealed, a development already implicit in Darwin's notion. (semanticscholar.org)
- In this work ergonomic adaptation of robotic movements during human-robot collaboration is explored in a first test case, namely, adjustment of work sureface height. (aau.dk)
- Nettle D. Selection, adaptation, inheritance and design in human culture: the view from the Price equation . (ncl.ac.uk)
- Is a sea slug a good [biological model] for a human therapy? (phys.org)
- One can suppose that all adaptations become second nature in the normal human experience. (answerbag.com)
- Well, I found this article, Pleistocene migration routes into the Americas: Human biological adaptations and environmental constraints, which hits most of the major points. (gnxp.com)
Limits2
- Identify the environmental limits for life by examining biological adaptations to extremes in environmental conditions. (nasa.gov)
- mitigation would mainly focus on stratagems required to limits further deterioration of the global climate and adaptation would address specific issues on how to reduce the severity of climate change due to past and future emission by mankind. (ukessays.com)
Theory1
- RECEIVED wisdom and biological theory both have it that males are (or, at least, would like to be) more promiscuous than females. (economist.com)
Survival1
- Plants have developed sophisticated mechanisms to sense the fluctuating availability of nutrients for their adaptation and survival under constantly changing atmospheric and soil conditions. (cell.com)